Compounds > olmesartan
Page last updated: 2024-09-04

olmesartan and atorvastatin

olmesartan has been researched along with atorvastatin in 6 studies

Compound Research Comparison

Studies
(olmesartan)		Trials
(olmesartan)		Recent Studies (post-2010)
(olmesartan)		Studies
(atorvastatin)		Trials
(atorvastatin)		Recent Studies (post-2010) (atorvastatin)
8411855547,4202,0583,782

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)atorvastatin (IC50)
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.0064
Insulin receptor Rattus norvegicus (Norway rat)0.0002
Prostaglandin G/H synthase 2Homo sapiens (human)0.0002
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0054
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Armstrong, ZB; Boughner, DR; Carruthers, CP; Drangova, M; Rogers, KA1
Brown, I; Gallivan, C1
O'Brien, E1

Other Studies

6 other study(ies) available for olmesartan and atorvastatin

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effects of an angiotensin II type 1 receptor blocker on aortic valve sclerosis in a preclinical model.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:9

    Topics: Angiotensin Receptor Antagonists; Animals; Aortic Valve; Atorvastatin; Bicuspid Aortic Valve Disease; Disease Progression; Heart Defects, Congenital; Heart Valve Diseases; Heptanoic Acids; Imidazoles; Immunohistochemistry; Male; Pyrroles; Rabbits; Random Allocation; Sclerosis; Tetrazoles

2014
Olmesartan induced enterocolitis.
    Pathology, 2014, Volume: 46, Issue:4

    Topics: Aged; Amitriptyline; Anticholesteremic Agents; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Atenolol; Atorvastatin; Dihydropyridines; Enterocolitis; Female; Heptanoic Acids; Humans; Imidazoles; Pyrroles; Tetrazoles

2014
If I had resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome

2014