olmesartan has been researched along with angiotensin ii in 69 studies
| Studies (olmesartan) | Trials (olmesartan) | Recent Studies (post-2010) (olmesartan) | Studies (angiotensin ii) | Trials (angiotensin ii) | Recent Studies (post-2010) (angiotensin ii) |
|---|---|---|---|---|---|
| 841 | 185 | 554 | 38,152 | 1,089 | 7,413 |
| Protein | Taxonomy | olmesartan (IC50) | angiotensin ii (IC50) |
|---|---|---|---|
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.002 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.002 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0018 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0055 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.004 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 34 (49.28) | 29.6817 |
| 2010's | 31 (44.93) | 24.3611 |
| 2020's | 4 (5.80) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuda, N; Ikeda, Y; Kanmatsuse, K; Suzuki, R; Tahira, Y; Takagi, H; Teng, J | 1 |
| Inoue, T; Koike, H; Yokoyoma, T | 1 |
| Asakura, M; Asanuma, H; Funaya, H; Hori, M; Kim, J; Kitakaze, M; Node, K; Ogita, H; Sanada, S; Takashima, S | 1 |
| Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Liao, Y; Minamino, T; Nagamachi, Y; Nakatani, T; Ogawa, S; Okada, K; Ozawa, K; Takashima, S; Tomoike, H; Tsukamoto, O; Tsukamoto, Y; Yutani, C | 1 |
| Horiuchi, M; Ide, A; Iwai, M; Li, HS; Li, JM; Min, LJ; Mogi, M; Okumura, M; Suzuki, H; Suzuki, J; Tsuda, M | 1 |
| Adachi, M; Hirano, T; Ran, J | 1 |
| Averill, DB; Brosnihan, KB; Ferrario, CM; Schiffrin, EL; Smith, RD; Yokoyama, H | 1 |
| Inoue, H; Nakamura, Y; Nishijima, T; Sakurai, S; Takahashi, S | 1 |
| Abe, T; Ikeda, T; Kawai, K; Nakagomi-Hagihara, R; Nakai, D; Tokui, T; Yoshigae, Y | 1 |
| Adachi, M; Fukui, T; Hirano, T; Kageyama, H; Okada, K; Ran, J; Saito, K | 1 |
| Abe, Y; Baba, R; Fan, YY; Fujita, M; Hosomi, N; Kimura, S; Kohno, M; Miyatake, A; Nagai, Y; Nishiyama, A; Sun, GP | 1 |
| Abe, H; Arai, H; Doi, T; Fukatsu, A; Iehara, N; Kanamori, H; Kita, T; Matsubara, T; Mima, A; Nagai, K; Sumi, E; Takahashi, T | 1 |
| Fujita, K; Funahashi, T; Hibuse, T; Hiuge, A; Kihara, S; Kumada, M; Kurata, A; Kuriyama, H; Maeda, N; Nishizawa, H; Ohashi, K; Okada, T; Shimomura, I; Sonoda, M; Yasui, A | 1 |
| Danser, AH; Krop, M; van Esch, JH | 1 |
| Hashizume, K; Nakamura, J; Shigematsu, S; Takeuchi, Y; Yamauchi, K | 1 |
| Agata, J; Hyakkoku, M; Sasaki, H; Shimamoto, K; Shinshi, Y; Taniguchi, S; Ura, N; Yoshida, H | 1 |
| Ahmed, RA; Cao, WM; Imachi, H; Ishida, T; Kosaka, H; Li, J; Matsumoto, K; Murao, K; Nishiuchi, T; Unterman, TG; Wong, NC; Yu, X | 1 |
| Fujimoto, N; Matsumoto, T; Nishii, H; Nomura, M; Ozaki, Y | 1 |
| Miura, S; Saku, K | 2 |
| Le, MT; Pugsley, MK; Van Liefde, I; Vauquelin, G | 1 |
| Arakawa, S; Fujimoto, S; Haruna, Y; Hatta, H; Horike, H; Kashihara, N; Kobayashi, S; Namikoshi, T; Satoh, M; Tomita, N | 1 |
| Kang, JJ; Meer, EJ; Peti-Peterdi, J; Sipos, A; Toma, I; Vargas, SL | 1 |
| Gonzalez-Villalobos, RA; Katsurada, A; Kobori, H; Miyata, K; Navar, LG; Ohashi, N; Satou, R | 1 |
| Ferrario, CM; Igase, M; Kohara, K; Miki, T; Nagai, T | 1 |
| Hashimoto, K; Horino, T; Inoue, K; Iwasaki, Y; Kagawa, T; Matsumoto, R; Morita, T; Taguchi, T; Takao, T; Terada, Y | 1 |
| Fujigaki, Y; Fukasawa, H; Hishida, A; Huang, Y; Kitagawa, M; Misaki, T; Nakagawa, T; Nakamura, Y; Ohashi, N; Suzuki, F; Suzuki, H; Suzuki, S; Togawa, A; Yamamoto, T | 1 |
| Fukuda, Y; Iino, Y; Ishizaki, M; Katayama, Y; Kawachi, H; Masuda, Y; Mii, A; Shimizu, A | 1 |
| Felder, RA; Hashimoto, S; Jose, PA; Sanada, H; Watanabe, T; Yatabe, J; Yatabe, MS; Yoneda, M | 1 |
| Endo, S; Hosoya, T; Ito, S; Miyata, T; Mori, T; Nakamichi, T; Ogawa, S; Tokudome, G; Yoneki, Y | 1 |
| Kubota, N; Matsuyama, N; Nakajima, T; Suzuki, H; Takeyama, Y; Tsutsumi, T | 1 |
| Ikeda, H; Jin, D; Miyazaki, M; Sakonjo, H; Takai, S | 1 |
| Fan, YY; Fujisawa, Y; Hase, N; Hitomi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsuura, J; Nakano, D; Nishiyama, A; Urata, H | 1 |
| Geot, WM; Horikoshi, S; Suzuki, Y; Takahashi, H; Tanifuji, C; Tomino, Y | 1 |
| Bouley, R; Brown, D; Ingelfinger, JR; Jung, FF; Kobori, H; Lu, HA; Nunes, P; Palomino, Z; Sabolic, I; Shum, WW; Tang, SS | 1 |
| Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T | 1 |
| Iwamoto, Y; Maekawa, Y; Ohishi, M; Ohnishi, M; Rakugi, H; Shiota, A; Takeda, M; Tatara, Y; Yamamoto, K | 1 |
| Bai, Y; Dejima, T; Hirawa, N; Horiuchi, M; Ichihara, N; Ishigami, T; Kobayashi, Y; Maeda, A; Masuda, S; Matsuda, M; Minamisawa, S; Mogi, M; Shigenaga, A; Tamura, K; Tanaka, Y; Toya, Y; Umemura, S; Wakui, H; Yabana, M | 1 |
| Isosaki, M; Kyotani, Y; Nakayama, H; Tomita, S; Uno, M; Yoshizumi, M; Zhao, J | 1 |
| Hayashi, N; Iwamoto, Y; Oguro, R; Ohishi, M; Rakugi, H; Shiota, A; Takeda, M; Takeya, Y; Tatara, Y; Yamamoto, K | 1 |
| Chen, R; Eisner, C; Hu, X; Huang, Y; Kopp, JB; Leelahavanichkul, A; Mizel, D; Schnermann, J; Star, RA; Wright, EC; Yan, Q; Yuen, PS; Zhou, H | 1 |
| Aizawa, Y; Gurusamy, N; Kodama, M; Ma, M; Sukumaran, V; Suzuki, K; Thandavarayan, RA; Veeraveedu, PT; Watanabe, K; Yamaguchi, K | 1 |
| Hitomi, H; Horiuchi, M; Hosomi, N; Kobori, H; Kohno, M; Matsumoto, M; Mogi, M; Nakano, D; Nishiyama, A; Pelisch, N; Sakamoto, H; Shimada, K; Ueno, M | 1 |
| Kim, HJ; Rodríguez-Iturbe, B; Sato, T; Vaziri, ND | 1 |
| Kageji, T; Kinouchi, T; Kitazato, KT; Nagahiro, S; Satomi, J; Shimada, K; Tada, Y; Yagi, K | 1 |
| Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I | 1 |
| Conte, D; Nishiyama, A; Ortiz, RM; Viscarra, J | 1 |
| Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A | 1 |
| Aoyama, Y; Fukaya, H; Izumi, T; Kiryu, M; Kishihara, J; Masaki, Y; Niwano, H; Niwano, S | 1 |
| Fujigaki, Y; Fukasawa, H; Hishida, A; Huang, Y; Ichihara, A; Ikegaya, N; Misaki, T; Nishiyama, A; Ohashi, N; Senbonmatsu, T; Suzuki, H; Togawa, A; Yamamoto, T | 1 |
| Hamada, J; Kobara, M; Nakata, T; Noda, K; Shiraishi, T; Tanaka, T; Toba, H; Wang, J; Yoshifuji, Y | 1 |
| Goette, A; Lendeckel, U; Wolke, C | 1 |
| Ge, J; Guo, J; Jiang, G; Li, L; Wang, S; Wu, J; You, J; Zou, Y | 1 |
| Andresen, BT; Mandavia, C; Meuth, A; Nistala, R; Pulakat, L; Sinak, C; Sowers, JR; Speth, RC; Thekkumkara, T; Whaley-Connell, A | 1 |
| Hitomi, H; Ichihara, A; Kobori, H; Kohno, M; Masaki, T; Mori, H; Morimoto, S; Murase, M; Nakano, D; Nishiyama, A; Ohmori, K; Ohnishi, K; Pelisch, N | 1 |
| Bin, J; Cao, S; Chen, B; Fu, Y; Huang, Q; Huang, X; Kitakaze, M; Liao, Y; Lu, D; Xu, D; Zhang, J | 1 |
| Cheng, XW; Dai, Q; Hao, C; Murohara, T; Wu, H; Yao, H; Zhang, Z | 1 |
| Fujigaki, Y; Kato, A; Nishiyama, A; Ohashi, N; Ono, M; Sakao, Y; Tsuji, T; Yasuda, H | 1 |
| Bin, J; Cao, S; Chen, C; Huang, X; Kitakaze, M; Li, G; Li, X; Liao, Y; Shen, L; Xu, D; Xuan, W; Zhang, J | 1 |
| Hayashi, M; Horimai, C; Yamashita, M; Yoshida, T | 1 |
| Cao, FF; Jiang, ZL; Li, YF; Liu, F | 1 |
| Aoki, M; Kawahata, H; Morishita, R; Nakagami, H; Ogihara, T; Shimizu, H; Sotobayashi, D | 1 |
| Chen, DR; Gao, PJ; Ruan, CC; Yan, C; Zhang, K; Zhang, ZB | 1 |
| Arimoto, M; Hata, H; Osaka, S; Sakino, H; Sezai, A; Shiono, M; Yaoita, H | 1 |
| Chen, J; Chen, M; Gu, J; He, L; Hu, H; Jing, Y; Li, L; Mei, C; Mei, S; Qi, N; Song, S; Sun, L; Wu, M; Wüthrich, RP; Yang, M | 1 |
| Arrabito, E; Battistoni, A; Filippini, A; Madaro, L; Nicoletti, C; Parente, R; Savoia, C; Steckelings, UM; Touyz, RM; Volpe, M | 1 |
| Bodakhe, SH; Choudhary, R; Shree, J; Singh, A | 1 |
| Abo-Salem, OM; El-Sayed, EM; Ismail, RS; Mohamed, BM; Saleh, IG | 1 |
| Ge, X; Wang, SN; Wu, Y; Zhang, CQ | 1 |
1 review(s) available for olmesartan and angiotensin ii
| Article | Year |
|---|---|
Recent progress in the treatment of cardiovascular disease using olmesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Coronary Artery Disease; Coronary Stenosis; Disease Models, Animal; Humans; Hypertension; Imidazoles; Plaque, Atherosclerotic; Tetrazoles | 2014 |
3 trial(s) available for olmesartan and angiotensin ii
| Article | Year |
|---|---|
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Tetrazoles | 2010 |
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Benzimidazoles; Biphenyl Compounds; Cardiac Surgical Procedures; Compliance; Drug Substitution; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome | 2011 |
Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study).
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Blood Pressure; Cardiac Surgical Procedures; Drug Substitution; Essential Hypertension; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Oxadiazoles; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Remodeling | 2016 |
65 other study(ies) available for olmesartan and angiotensin ii
| Article | Year |
|---|---|
Inhibitory effect of a novel angiotensin II type 1 receptor antagonist RNH-6270 on growth of vascular smooth muscle cells from spontaneously hypertensive rats: different anti-proliferative effect to angiotensin-converting enzyme inhibitor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Cell Division; Cells, Cultured; Fibroblast Growth Factor 2; Imidazoles; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thiazepines; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
The effect of angiotensin II on uveoscleral outflow in rabbits.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anterior Chamber; Aqueous Humor; Ciliary Body; Dextrans; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Imidazoles; Intraocular Pressure; Male; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sclera; Tetrazoles | 2001 |
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers synergistically increase coronary blood flow in canine ischemic myocardium: role of bradykinin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Circulation; Coronary Vessels; Dogs; Drug Synergism; Imidazoles; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Angiotensin; Tetrazoles; Thiazepines; Vasodilation | 2002 |
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve Stenosis; Apoptosis; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Progression; Endoplasmic Reticulum; Gene Expression Regulation; Heart Failure; Humans; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Myocytes, Cardiac; Natriuretic Peptide, Brain; Olmesartan Medoxomil; Rats; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Stress, Physiological; Tetrazoles; Thapsigargin; Tunicamycin | 2004 |
Inhibitory effects of AT1 receptor blocker, olmesartan, and estrogen on atherosclerosis via anti-oxidative stress.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Enzyme Activation; Estradiol; Female; Imidazoles; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Ovariectomy; Oxidative Stress; Tetrazoles | 2005 |
Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Fatty Acids, Nonesterified; Imidazoles; Liver; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Triglycerides; Vasoconstrictor Agents | 2005 |
Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiomegaly; Collagen; Disease Progression; Endothelium, Vascular; Heart Rate; Hypertension; Imidazoles; Male; Mesenteric Arteries; Myocardium; Rats; Rats, Inbred SHR; Tetrazoles; Vascular Diseases; Vascular Resistance | 2005 |
Essential roles of angiotensin II in vascular endothelial growth factor expression in sleep apnea syndrome.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cells, Cultured; Female; Gene Expression Regulation; Humans; Imidazoles; Leukocytes; Male; Middle Aged; Neutrophils; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sleep Apnea Syndromes; Tetrazoles; Vascular Endothelial Growth Factor A | 2005 |
OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker.
Topics: Angiotensin II; Animals; Area Under Curve; Bile; Bile Canaliculi; Cell Line; Cell Membrane; Female; Hepatocytes; Humans; Imidazoles; Liver; Liver-Specific Organic Anion Transporter 1; Male; Mitochondrial Proteins; Oocytes; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazoles; Xenopus laevis | 2006 |
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance.
Topics: Adiponectin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Imidazoles; Injections, Subcutaneous; Insulin; Insulin Resistance; Leptin; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Adiponectin; Receptors, Cell Surface; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Collagen; Connective Tissue Growth Factor; Creatine; Hypertension; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Male; Nephrectomy; Organ Size; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Chloride; Tetrazoles; Transforming Growth Factor beta | 2006 |
Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Butadienes; Cell Line; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression; Glomerular Mesangium; Imidazoles; Male; Mesangial Cells; Nitriles; Phosphorylation; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Smad1 Protein; src-Family Kinases; Tetrazoles | 2006 |
Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation.
Topics: Adiponectin; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Female; Gene Expression Regulation; Imidazoles; Kidney Diseases; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; RNA, Messenger; Serum Amyloid A Protein; Signal Transduction; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Letter by Krop et al regarding article, "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium".
Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Buffers; Captopril; Diabetes Complications; Diabetes Mellitus, Experimental; Diffusion; Free Radical Scavengers; Imidazoles; Kallikreins; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Perfusion; Rats; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 90-kDa; Species Specificity; Tetrazoles | 2006 |
Angiotensin II regulates migration in mouse cultured mesangial cells: evidence for the presence of receptor subtype-specific regulation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cell Movement; Cell Proliferation; Cells, Cultured; Imidazoles; Immunoblotting; Mesangial Cells; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2006 |
Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Gene Expression; Imidazoles; Male; Myocardium; Nitrates; Nitrites; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Ventricular Remodeling | 2006 |
Regulation of scavenger receptor class BI gene expression by angiotensin II in vascular endothelial cells.
Topics: Androstadienes; Angiotensin II; Cells, Cultured; Chromones; Down-Regulation; Endothelium, Vascular; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Imidazoles; Morpholines; Nitric Oxide Synthase; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class B; Tetrazoles; Wortmannin | 2007 |
An angiotensin II receptor blocker increases sexual behavior in type 2 diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Exploratory Behavior; Female; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Reaction Time; Receptor, Angiotensin, Type 1; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Species Specificity; Tetrazoles; Time Factors | 2007 |
Do all angiotensin II type 1 receptor blockers have the same beneficial effects?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Humans; Imidazoles; Molecular Structure; Protein Binding; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles | 2007 |
Molecular characterisation of the interactions between olmesartan and telmisartan and the human angiotensin II AT1 receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imidazoles; Inositol Phosphates; Molecular Structure; Protein Binding; Radioligand Assay; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Time Factors; Tritium | 2007 |
Olmesartan ameliorates progressive glomerular injury in subtotal nephrectomized rats through suppression of superoxide production.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Imidazoles; Kidney Glomerulus; Male; NADPH Oxidases; Nephrectomy; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Superoxides; Tetrazoles | 2008 |
The collecting duct is the major source of prorenin in diabetes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertension, Renal; Imidazoles; Immunohistochemistry; Juxtaglomerular Apparatus; Kidney Tubules, Collecting; Microscopy, Fluorescence; Quinacrine; Rats; Rats, Wistar; Renin; Tetrazoles; Trypsin; Vasoconstrictor Agents | 2008 |
Costimulation with angiotensin II and interleukin 6 augments angiotensinogen expression in cultured human renal proximal tubular cells.
Topics: Angiotensin II; Angiotensinogen; Cells, Cultured; Humans; Imidazoles; Interleukin-6; Kidney Tubules, Proximal; NF-kappa B; RNA, Messenger; STAT3 Transcription Factor; Tetrazoles; Up-Regulation | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
Effects of angiotensin II type 1 receptor blocker on albumin-induced cell damage in human renal proximal tubular epithelial cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylglucosaminidase; Albumins; Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cells, Cultured; Deoxyguanosine; Dose-Response Relationship, Drug; Humans; Imidazoles; Kidney Tubules, Proximal; NADPH Oxidases; Oxidative Stress; Tetrazoles; Valine; Valsartan | 2009 |
Intrarenal RAS activity and urinary angiotensinogen excretion in anti-thymocyte serum nephritis rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Antilymphocyte Serum; Blood Pressure; Gene Expression; Glomerulonephritis, Membranoproliferative; Imidazoles; Kidney; Male; Proteinuria; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles | 2008 |
Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Becaplermin; Biomarkers; Blood Pressure; Cell Proliferation; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Imidazoles; Kidney Glomerulus; Male; Platelet-Derived Growth Factor; Proteinuria; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thy-1 Antigens | 2009 |
Angiotensin II type 1 receptor blocker attenuates the activation of ERK and NADPH oxidase by mechanical strain in mesangial cells in the absence of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autocrine Communication; Cells, Cultured; Chelating Agents; Cytochalasin D; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hypertension, Renal; Imidazoles; Male; Mesangial Cells; MicroRNAs; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Paracrine Communication; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stress, Mechanical; Tetrazoles; Vasoconstrictor Agents | 2009 |
Blockade of angiotensin II type-1 receptor increases salt sensitivity in Sprague-Dawley rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Circadian Rhythm; Diuretics; Imidazoles; Male; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium; Sodium, Dietary; Telemetry; Tetrazoles | 2009 |
Direct action of an angiotensin II receptor blocker on angiotensin II-induced left atrial conduction delay in spontaneously hypertensive rats.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Electric Stimulation; Heart Atria; Heart Conduction System; Hypertension; Imidazoles; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 2009 |
Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Hypertension; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; Peptidyl-Dipeptidase A; Protective Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetrazoles; Valine; Valsartan; Vascular Diseases | 2009 |
Contribution of chymase-dependent angiotensin II formation to the progression of tubulointerstitial fibrosis in obstructed kidneys in hamsters.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blood Urea Nitrogen; Butyrates; Chymases; Collagen Type I; Cricetinae; Disease Progression; Imidazoles; Kidney; Male; Mesocricetus; Nephritis, Interstitial; Organ Size; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Transforming Growth Factor beta; Ureteral Obstruction | 2009 |
Beneficial effects of combination therapy with olmesartan and azelnidipine in murine polycystic kidneys.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Blotting, Western; Calcium Channel Blockers; Dihydropyridines; Drug Synergism; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Imidazoles; Immunohistochemistry; Kidney; Mice; NADPH Oxidases; Nitric Oxide Synthase Type III; Polycystic Kidney Diseases; Tetrazoles | 2009 |
Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 1; Cell Line, Transformed; Diuresis; Dose-Response Relationship, Drug; Drug Synergism; Hypertonic Solutions; Imidazoles; Kidney; Kidney Tubules, Proximal; Loop of Henle; Losartan; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride; Tetrazoles; Time Factors | 2009 |
Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrons; Peptidyl-Dipeptidase A; Phenotype; Receptor, Angiotensin, Type 1; Tetrazoles | 2010 |
Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiac hypertrophy in chronic angiotensin II-infused mice.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Cardiomegaly; Genotype; Heart Rate; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mitogen-Activated Protein Kinase Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazoles | 2010 |
Olmesartan inhibits angiotensin II-Induced migration of vascular smooth muscle cells through Src and mitogen-activated protein kinase pathways.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atherosclerosis; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases; Tetrazoles | 2010 |
The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Tetrazoles | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Glomerulonephritis; Heart Diseases; Hydralazine; Hypertension; Imidazoles; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Kidney Diseases; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nephrectomy; Sodium Chloride, Dietary; Species Specificity; Telemetry; Tetrazoles; Time Factors; X-Ray Microtomography | 2010 |
Beneficial effects of olmesartan, an angiotensin II receptor type 1 antagonist, in rats with dilated cardiomyopathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiomyopathy, Dilated; Chemokine CCL2; Imidazoles; Interleukin-1beta; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocarditis; Myocardium; Myosins; Rats; Rats, Inbred Lew; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2010 |
Blockade of AT1 receptors protects the blood-brain barrier and improves cognition in Dahl salt-sensitive hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood-Brain Barrier; Body Weight; Capillary Permeability; Cognition; Corpus Callosum; Hippocampus; Hypertension; Imidazoles; Immunohistochemistry; Male; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Inbred Dahl; RNA, Messenger; Systole; Tetrazoles | 2011 |
Role of intrarenal angiotensin system activation, oxidative stress, inflammation, and impaired nuclear factor-erythroid-2-related factor 2 activity in the progression of focal glomerulosclerosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Progression; Glomerulosclerosis, Focal Segmental; Hypertension; Imidazoles; Kidney; Kidney Diseases; Male; NF-E2 Transcription Factor; NF-kappa B; Oxidative Stress; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Tetrazoles; Thiobarbituric Acid Reactive Substances | 2011 |
Activation of estrogen receptor-α and of angiotensin-converting enzyme 2 suppresses ischemic brain damage in oophorectomized rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Blotting, Western; Brain; Brain Ischemia; Caspase 3; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Female; Gene Expression; Imidazoles; Immunohistochemistry; Ovariectomy; Peptidyl-Dipeptidase A; Phenols; Pyrazoles; ras Proteins; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles | 2011 |
Chronic angiotensin receptor blockade suppresses intracardiac angiotensin II in angiotensin II-infused rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Heart; Imidazoles; Kidney; Male; Myocardium; Rats; Rats, Sprague-Dawley; Tetrazoles | 2011 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Eplerenone; Genes, p16; Genes, p53; Hydralazine; Hypertension; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; p21-Activated Kinases; Sirtuin 1; Sodium Chloride; Spironolactone; Tetrazoles | 2012 |
Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Blotting, Western; Connective Tissue Growth Factor; Disease Models, Animal; Dogs; Extracellular Matrix; Female; Heart Atria; Imidazoles; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazoles; Up-Regulation | 2012 |
Enhanced intrarenal receptor-mediated prorenin activation in chronic progressive anti-thymocyte serum nephritis rats on high salt intake.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antilymphocyte Serum; Blood Pressure; Hydralazine; Imidazoles; Kidney; Male; Nephritis; Prorenin Receptor; Rats; Rats, Wistar; Receptors, Cell Surface; Renin; Sodium Chloride, Dietary; T-Lymphocytes; Tetrazoles | 2012 |
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Hemodynamics; Imidazoles; Lipid Peroxidation; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Ventricular Function, Left | 2012 |
Atrial fibrillation and fibrosis: role of connective tissue growth factor.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Connective Tissue Growth Factor; Female; Heart Atria; Imidazoles; Tetrazoles | 2012 |
Olmesartan attenuates cardiac remodeling through DLL4/Notch1 pathway activation in pressure overload mice.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium-Binding Proteins; Dipeptides; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Notch1; Tetrazoles; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling | 2013 |
Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Binding Sites; Cell Line; Drug Resistance; Humans; Imidazoles; Iodine Radioisotopes; Janus Kinase 2; Kidney Tubules, Proximal; Opossums; Phylogeny; Polymorphism, Genetic; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Species Specificity; Tetrazoles; Vasoconstrictor Agents | 2013 |
Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Imidazoles; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Thiazepines | 2013 |
Olmesartan prevents cardiac rupture in mice with myocardial infarction by modulating growth differentiation factor 15 and p53.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Cells, Cultured; Fibroblasts; Growth Differentiation Factor 15; Heart Rupture; Hypoxia; Imidazoles; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Peroxidase; Tetrazoles; Tumor Suppressor Protein p53 | 2014 |
Regulation of apelin and its receptor expression in adipose tissues of obesity rats with hypertension and cultured 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apelin; Apelin Receptors; Gene Expression; Gene Expression Regulation; Hypertension; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Obesity; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Tetrazoles | 2014 |
Role of intrarenal (pro)renin receptor in ischemic acute kidney injury in rats.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Creatinine; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Ischemia; Kidney Tubules; Male; NF-kappa B; Phosphorylation; Prorenin Receptor; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Sodium Chloride; Tetrazoles; Vacuolar Proton-Translocating ATPases | 2015 |
Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulation.
Topics: Adenoviridae; Angiotensin II; Animals; Animals, Newborn; Aorta; Atrial Natriuretic Factor; Calcineurin; Calpain; Cardiomegaly; Constriction, Pathologic; Cyclosporine; Gene Expression Regulation; Genetic Vectors; Glycoproteins; Imidazoles; Mice; Muscle Proteins; Myocytes, Cardiac; Myosin Heavy Chains; Nuclear Proteins; Primary Cell Culture; Protein Transport; Rats; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Tetrazoles | 2014 |
Kruppel-like factor 4 protein regulates isoproterenol-induced cardiac hypertrophy by modulating myocardin expression and activity.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cardiomegaly; Cell Line; Gene Expression; Gene Expression Regulation; Histone Deacetylase Inhibitors; Hydroxamic Acids; Imidazoles; Isoproterenol; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; Natriuretic Peptide, C-Type; Nuclear Proteins; Protein Precursors; Tetrazoles; Trans-Activators | 2014 |
Effects of olmesartan therapy on the expression of lung adrenoceptors in rats with chronic heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Chronic Disease; Heart Failure; Imidazoles; Lung; Male; Rats; Rats, Wistar; Receptors, Adrenergic; Renin; RNA, Messenger; Tetrazoles | 2015 |
Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Cell Differentiation; Cell Enlargement; Chondrocytes; Chondrogenesis; Collagen Type X; Core Binding Factor Alpha 1 Subunit; Growth Plate; Imidazoles; Infusions, Intravenous; Matrix Metalloproteinase 13; Mice; Renin-Angiotensin System; Rib Fractures; SOX9 Transcription Factor; Tetrazoles | 2015 |
Activating transcription factor 3 SUMOylation is involved in angiotensin II-induced endothelial cell inflammation and dysfunction.
Topics: Activating Transcription Factor 3; Angiotensin II; Animals; Aorta; Endothelial Cells; Gene Expression Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Interleukin-6; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; SUMO-1 Protein; Sumoylation; Tetrazoles; Vasodilation | 2016 |
Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis.
Topics: Albuminuria; Angiotensin II; Animals; Apoptosis; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Imidazoles; Male; Mice; Mice, Inbred Strains; p38 Mitogen-Activated Protein Kinases; Podocytes; Sirtuin 1; Tetrazoles | 2016 |
Mas Receptor Activation Contributes to the Improvement of Nitric Oxide Bioavailability and Vascular Remodeling During Chronic AT1R (Angiotensin Type-1 Receptor) Blockade in Experimental Hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Hypertension; Imidazoles; Mesenteric Arteries; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Tetrazoles; Vascular Remodeling; Vasodilation | 2020 |
Role of the renin-angiotensin system in the development of cataract formation in angiotensin-II-induced experimental rats.
Topics: Angiotensin II; Animals; Cataract; Imidazoles; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles | 2021 |
Olmesartan ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats via Nrf2/HO-1 signaling pathway.
Topics: Angiotensin II; Animals; Carboxymethylcellulose Sodium; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Cytokines; Heme Oxygenase (Decyclizing); Imidazoles; Inflammation Mediators; Interleukin-6; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tetrazoles; Tumor Necrosis Factor-alpha | 2022 |
Olmesartan Improves Hepatic Sinusoidal Remodeling in Mice with Carbon Tetrachloride-Induced Liver Fibrosis.
Topics: Angiotensin II; Animals; Carbon Tetrachloride; Collagen; Imidazoles; Interleukin-10; Liver Cirrhosis; Mice; Neovascularization, Pathologic; Tetrazoles; Vascular Endothelial Growth Factor A | 2022 |