olmesartan has been researched along with amlodipine in 103 studies
| Studies (olmesartan) | Trials (olmesartan) | Recent Studies (post-2010) (olmesartan) | Studies (amlodipine) | Trials (amlodipine) | Recent Studies (post-2010) (amlodipine) |
|---|---|---|---|---|---|
| 841 | 185 | 554 | 4,200 | 1,504 | 1,671 |
| Protein | Taxonomy | olmesartan (IC50) | amlodipine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | 1.2 | |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | 0.4 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.602 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.8 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 2.898 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 5.521 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 2.7 | |
| Potassium channel subfamily K member 2 | Bos taurus (cattle) | 0.43 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (11.65) | 29.6817 |
| 2010's | 83 (80.58) | 24.3611 |
| 2020's | 8 (7.77) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Fujii, S; Furumoto, T; Katoh, C; Morita, K; Naya, M; Tamaki, N; Tsukamoto, T; Tsutsui, H | 1 |
| Oparil, S; Pimenta, E | 1 |
| Allison, M; Bathala, MS; Haworth, S; Heyrman, R; Lee, J; Noveck, R; Rohatagi, S; Rubets, I; Salazar, DE; Shenouda, M | 1 |
| Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I; Tomono, Y | 1 |
| Pimenta, E | 1 |
| Ansari, A; Braun, N; Handrock, R; Klebs, S; Ulmer, HJ | 1 |
| Chavanu, KJ; Dubiel, R; Rosendorff, C; Xu, J | 1 |
| Futai, R; Ito, T; Kawanishi, Y; Kitaura, Y; Terasaki, F | 1 |
| Vivencio, B | 1 |
| Kawahira, K; Matsumoto, S; Miyata, R; Shimodozono, M | 1 |
| Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohira, M; Oyama, T; Saiki, A; Shirai, K; Yamaguchi, T | 1 |
| Dohi, Y; Kimura, G; Miyagawa, K; Nakazawa, A; Sato, K; Sugiura, T; Yamashita, S | 1 |
| Chrysant, SG; Heyrman, R; Karki, S; Lee, J; Melino, M | 1 |
| Corradi, L; Derosa, G; Fogari, R; Malamani, G; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Dubiel, R; Kereiakes, DJ; Maa, JF; Neutel, JM; Punzi, H; Shojaee, A; Waverczak, WF | 1 |
| Patil, KR; Rane, VP; Sangshetti, JN; Shinde, DB; Yeole, RD | 1 |
| Hoshino, A; Matsubara, H; Nakamura, T | 1 |
| Ferrario, CM; Smith, RD | 1 |
| Bramlage, P; Erdlenbruch, W; Fronk, EM; Ketelhut, R; Schmieder, RE; Stuhr, T; Wolf, WP | 1 |
| Bilo, G; Hoshide, S; Lonati, L; Ochoa, JE; Parati, G; Ramos, C | 1 |
| Bramlage, P; Erdlenbruch, W; Fronk, EM; Ketelhut, R; Schmieder, RE; Stuhr, T; Wasem, J; Wolf, WP | 1 |
| Comi-Diaz, C; Martinez-Martin, FJ; Pedrianes-Martin, P; Peiro-Martinez, I; Rodriguez-Rosas, H; Soriano-Perera, P | 1 |
| Alvarez-Martín, C; Belén Ferro-Rey, M; de Salas-Cansado, M; Roca-Cusachs, A; Sicras-Mainar, A | 1 |
| Makris, T; Stefanadis, C; Thomopoulos, C; Tsioufis, C | 1 |
| McInnes, GT | 1 |
| Kreutz, R | 1 |
| Ruilope, LM; Schaefer, A | 1 |
| Ando, K; Fujita, T; Haneda, M; Ito, S; Kashihara, N; Kishimoto, J; Nangaku, M; Node, K; Shimosawa, T | 1 |
| Graff, A; Hsueh, WA; Jones, CJ; Littlejohn, TJ; Nesbitt, SD; Neutel, JM; Qian, C; Shojaee, A; Waverczak, WF; Weir, MR | 1 |
| Maa, JF; Punzi, H; Shojaee, A; Waverczak, WF | 1 |
| Saito, Y; Takami, T | 2 |
| Narkiewicz, K | 1 |
| Ideno, S; Kobari, M; Nakada, T; Oiwa, T; Yaguchi, A | 1 |
| Axthelm, C; Kaiser, E; Meister, F; Sieder, C | 1 |
| Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn Iii, T; Melino, M; Oparil, S | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A | 1 |
| Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn, T; Melino, M; Oparil, S | 2 |
| Arakawa, K; Jinnouchi, H; Jinnouchi, T; Kim-Mitsuyama, S; Matsui, K; Ogawa, H | 2 |
| Daikuhara, H; Ishida, T; Kikuchi, F | 1 |
| Maa, JF; Neutel, J; Shojaee, A | 1 |
| Rich, MW | 1 |
| Adachi, H; Hoshizaki, H; Kasama, S; Kawaguchi, R; Koyama, K; Murakami, J; Oshima, S; Sato, C; Toyama, T; Yamashita, E | 1 |
| Ammentorp, B; Christian Rump, L; Laeis, P; Volpe, M | 1 |
| Carbone, A; Cicero, AF; D'Angelo, A; Derosa, G; Fogari, E; Maffioli, P; Querci, F | 5 |
| Paneni, F; Passerini, J; Tocci, G; Volpe, M | 1 |
| Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H | 1 |
| Buzinec, P; Ferrario, CM; Panjabi, S; Swindle, JP | 1 |
| Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T | 1 |
| de la Sierra, A; Volpe, M | 1 |
| Hou, CJ; Hsia, CH; Lai, WT; Lin, TH; Pan, JP; Tsai, CD; Tsai, JP | 1 |
| Di Renzo, G; Izzo, R; Manzi, MV; Marino, M; Rozza, F; Santoro, M; Trimarco, B; Trimarco, V | 1 |
| Iribe, G; Ito, H; Kaihara, K; Naruse, K | 1 |
| Hu, P; Jiang, J; Qi, W; Zhao, Q | 1 |
| Chrysant, SG | 1 |
| Bramlage, P; Fimmers, R; Gansz, A; Lüders, S; Nadal, J; Schmieder, RE; Schrader, J; Sturm, CD; Zemmrich, C | 2 |
| Ruilope, L; Schaefer, A | 1 |
| Andreeva, AA | 1 |
| de la Sierra, A; Kreutz, R; Laurent, S; Manolis, AJ; Volpe, M | 1 |
| Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Smolnik, R; Wolf, WP; Zemmrich, C | 1 |
| Ammentorp, B; de la Sierra, A; Laeis, P; Volpe, M | 1 |
| Bilo, G; Hoshide, S; Koch, W; Parati, G | 1 |
| O'Brien, E | 1 |
| Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H | 1 |
| Ammentorp, B; de la Sierra, A; Kreutz, R; Laeis, P | 1 |
| Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A | 1 |
| Ott, C; Raff, U; Schmieder, RE; Schneider, MP; Walker, S | 1 |
| Bramlage, P; Fronk, EM; Schmieder, RE; Smolnik, R; Sutton, G; Wolf, WP | 1 |
| Schlimpert, V | 1 |
| Ahn, Y; Bae, JH; Jung, HW; Kang, DH; Kim, CH; Kim, KI; Park, CG | 1 |
| Brazier, JE; Guest, JF; Haag, U; Marques da Silva, P; Soro, M | 1 |
| Ruilope, LM | 1 |
| Pichler, G; Redon, J | 2 |
| Abdelhameed, AS; Bakheit, AH; Darwish, HW | 1 |
| Cricelli, C; Cricelli, I; Lapi, F; Levi, M; Parretti, D; Pasqua, A; Piccinni, C | 1 |
| D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM | 1 |
| Drenjancevic, I; Mihalj, M; Rucevic, S; Tadzic, R; Vcev, A | 1 |
| Buendia, R; Zambrano, M | 1 |
| Douros, A; Kreutz, R; Scholze, J | 1 |
| Armario, P; Banegas, JR; de la Cruz, JJ; de la Sierra, A; Gorostidi, M; Oliveras, A; Ruilope, LM; Segura, J; Vinyoles, E | 1 |
| Okamura, K; Shirai, K; Takamiya, Y; Urata, H; Yano, Y | 1 |
| Chen, DR; Chen, J; Gao, PJ; Han, WQ; Jiang, H; Ruan, CC | 1 |
| Ahn, KT; Cho, BR; Kim, BJ; Kim, DK; Lee, SY; Lee, WS; Park, JI; Sung, J | 1 |
| Lauder, L; Mahfoud, F; Meyer, MR; Vollmer, AC; Wagmann, L | 1 |
| Burnier, M; Redon, J; Volpe, M | 1 |
| Abe, T; Bekki, M; Fukumoto, Y; Honda, A; Igata, S; Kurata, S; Maeda-Ogata, S; Matsui, T; Nishino, Y; Sugiyama, Y; Tahara, A; Tahara, N; Yamagishi, SI | 1 |
| Hong, JH; Hyun, D; Kim, GH; Kim, HL; Kim, W; Lim, S; Min, KW; Oh, J; Park, SD; Shin, J | 1 |
| Chen, X; Jia, S; Li, X; Liao, H; Liu, K; Liu, X; Meng, Q; Shi, R; Sun, L; Wang, S; Wang, Z; Xu, M; Ye, R; Zhang, X; Zhang, Z | 1 |
10 review(s) available for olmesartan and amlodipine
| Article | Year |
|---|---|
Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Drug Combinations; Humans; Hypertension; Imidazoles; Patient Compliance; Tablets; Tetrazoles | 2008 |
Olmesartan/Amlodipine: combination therapy for the treatment of hypertension [corrected].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Combinations; Humans; Hypertension; Imidazoles; Medication Adherence; Tetrazoles | 2009 |
Role of olmesartan in combination therapy in blood pressure control and vascular function.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Vessels; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tetrazoles | 2010 |
Efficacy and tolerability of olmesartan/amlodipine combination therapy in patients with mild-to-severe hypertension: focus on 24-h blood pressure control.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Severity of Illness Index; Tetrazoles | 2010 |
Olmesartan/amlodipine: a review of its use in the management of hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Evidence-Based Medicine; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome | 2011 |
Angiotensin II receptor blocker combinations: from guidelines to clinical practice.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Practice Guidelines as Topic; Tetrazoles | 2012 |
Triple combination therapy to improve blood pressure control: experience with olmesartan-amlodipine-hydrochlorothiazide therapy.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles | 2012 |
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2013 |
Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD.
Topics: Age Factors; Amlodipine; Cardiovascular Diseases; Diabetes Complications; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Renal Insufficiency, Chronic; Tetrazoles | 2013 |
Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Olmesartan Medoxomil | 2023 |
51 trial(s) available for olmesartan and amlodipine
| Article | Year |
|---|---|
Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Patient Compliance; Prospective Studies; Tetrazoles; Valine; Valsartan | 2009 |
Comparison of olmesartan medoxomil versus amlodipine besylate on regression of ventricular and vascular hypertrophy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome | 2009 |
Olmesartan ameliorates myocardial function independent of blood pressure control in patients with mild-to-moderate hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Echocardiography, Doppler, Color; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Inflammation; Male; Middle Aged; Myocardium; Severity of Illness Index; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Function, Left | 2009 |
Benefits of the angiotensin II receptor antagonist olmesartan in controlling hypertension and cerebral hemodynamics after stroke.
Topics: Acetazolamide; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Circulation; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Stroke; Stroke Rehabilitation; Tetrazoles; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2009 |
Effects of olmesartan, an angiotensin II receptor blocker, and amlodipine, a calcium channel blocker, on Cardio-Ankle Vascular Index (CAVI) in type 2 diabetic patients with hypertension.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Ankle; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Deoxyguanosine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypertension; Imidazoles; Lipids; Male; Middle Aged; Tetrazoles | 2009 |
Renoprotective effect of calcium channel blockers in combination with an angiotensin receptor blocker in elderly patients with hypertension. A randomized crossover trial between benidipine and amlodipine.
Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Renal Insufficiency, Chronic; Tetrazoles | 2010 |
Efficacy and tolerability of amlodipine plus olmesartan medoxomil in patients with difficult-to-treat hypertension.
Topics: Age Factors; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; United States; Vasodilator Agents | 2010 |
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Ankle Joint; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Norepinephrine; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Efficacy of amlodipine and olmesartan medoxomil in patients with hypertension: the AZOR Trial Evaluating Blood Pressure Reductions and Control (AZTEC) study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; United States; Vasodilator Agents | 2010 |
The bedtime administration ameliorates blood pressure variability and reduces urinary albumin excretion in amlodipine-olmesartan combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Creatinine; Drug Chronotherapy; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2010 |
Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2010 |
Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.
Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Comorbidity; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2011 |
Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action
Topics: Adult; Aged; Albuminuria; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Middle Aged; Research Design; Sympatholytics; Tetrazoles | 2011 |
A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Self Report; Tetrazoles; Titrimetry; Young Adult | 2011 |
Effects of Azelnidipine plus OlmesaRTAn versus amlodipine plus olmesartan on central blood pressure and left ventricular mass index: the AORTA study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Ultrasonography | 2011 |
Efficacy and tolerability of the single-pill combination of aliskiren 300 mg/amlodipine 10 mg in hypertensive patients not controlled by olmesartan 40 mg/amlodipine 10 mg.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Resistance; Drug Substitution; Female; Fumarates; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Young Adult | 2012 |
24-hour efficacy and safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors | 2011 |
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2012 |
Long-term efficacy and safety of triple-combination therapy with olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide for hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors | 2012 |
Angiotensin II receptor blocker-based therapy in Japanese elderly, high-risk, hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Single-Blind Method; Survival Analysis; Tetrazoles; Treatment Outcome | 2012 |
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome | 2012 |
Efficacy of amlodipine/olmesartan ± hydrochlorothiazide in patients uncontrolled on prior calcium channel blocker or angiotensin II receptor blocker monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Comorbidity; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2012 |
Triple-Combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: the TRINITY randomized, double-blind, 12-week, parallel-group study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles | 2012 |
Olmesartan improves coronary flow reserve of hypertensive patients using coronary magnetic resonance imaging compared with amlodipine.
Topics: Adenosine; Adult; Aged; Amlodipine; Antihypertensive Agents; Coronary Circulation; Echocardiography; Female; Humans; Hypertension; Imidazoles; Magnetic Resonance Angiography; Male; Middle Aged; Stroke Volume; Tetrazoles; Vasodilator Agents; Ventricular Function, Left | 2012 |
Efficacy and safety of triple antihypertensive therapy with the olmesartan/amlodipine/hydrochlorothiazide combination.
Topics: Adult; Aged; Aging; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Young Adult | 2012 |
Olmesartan/amlodipine combination versus olmesartan or amlodipine monotherapies on blood pressure and insulin resistance in a sample of hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2013 |
Effects of an olmesartan/amlodipine fixed dose on blood pressure control, some adipocytokines and interleukins levels compared with olmesartan or amlodipine monotherapies.
Topics: Adipokines; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Interleukins; Male; Middle Aged; Tetrazoles; Time Factors | 2013 |
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Efficacy and tolerability between an olmesartan/amlodipine fixed-dose combination and an amlodipine double dose in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2013 |
Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration.
Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chi-Square Distribution; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Female; Humans; Hypertension; Hypoglycemic Agents; Imidazoles; Italy; Male; Medication Adherence; Middle Aged; Monte Carlo Method; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome | 2013 |
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial.
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Diastole; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness; Ventricular Function, Left | 2013 |
Evaluation of safety and efficacy of a fixed olmesartan/amlodipine combination therapy compared to single monotherapies.
Topics: Adipokines; Amlodipine; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin; Insulin Resistance; Interleukin-10; Interleukin-8; Lipids; Male; Middle Aged; Tetrazoles | 2013 |
Results from a 12 months, randomized, clinical trial comparing an olmesartan/amlodipine single pill combination to olmesartan and amlodipine monotherapies on blood pressure and inflammation.
Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles | 2014 |
Different aspects of sartan + calcium antagonist association compared to the single therapy on inflammation and metabolic parameters in hypertensive patients.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles | 2014 |
Daytime systolic ambulatory blood pressure with a direct switch between candesartan monotherapy and the fixed-dose combination olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-1).
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Systole; Tetrazoles; Treatment Outcome | 2013 |
The fixed-dose combination of olmesartan/amlodipine was superior in central aortic blood pressure reduction compared with perindopril/amlodipine: a randomized, double-blind trial in patients with hypertension.
Topics: Adult; Aged; Amlodipine; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Multivariate Analysis; Perindopril; Risk Assessment; Tetrazoles; Treatment Outcome | 2013 |
Daytime systolic ambulatory blood pressure with a two-step switch from candesartan to olmesartan monotherapy and the fixed-dose combination of olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-2).
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; White People | 2014 |
Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study.
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Risk Factors; Sex Factors; Tetrazoles; Treatment Outcome | 2014 |
Open-label study assessing the long-term efficacy and safety of triple olmesartan/amlodipine/hydrochlorothiazide combination therapy for hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time; Treatment Outcome | 2014 |
Efficacy of olmesartan/amlodipine combination therapy in reducing ambulatory blood pressure in moderate-to-severe hypertensive patients not controlled by amlodipine alone.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Retreatment; Tetrazoles; Treatment Outcome | 2014 |
Efficacy and tolerability of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide: a subgroup analysis of patients stratified by hypertension severity, age, sex, and obesity.
Topics: Adult; Age Factors; Aged; Amlodipine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Sex Factors; Tetrazoles | 2014 |
Olmesartan improves pulse wave velocity and lowers central systolic blood pressure and ambulatory blood pressure in patients with metabolic syndrome.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Hemodynamics; Humans; Imidazoles; Male; Metabolic Syndrome; Middle Aged; Pulse Wave Analysis; Tetrazoles; Treatment Outcome; Vascular Stiffness | 2015 |
A multicenter, non-comparative study to evaluate the efficacy and safety of fixed-dose olmesartan/amlodipine in Korean patients with hypertension who are naïve or non-responders to anti-hypertensive monotherapy (ACE-HY study).
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Prospective Studies; Republic of Korea; Tetrazoles; Treatment Outcome | 2015 |
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Quality of Life; Tetrazoles; Treatment Outcome | 2015 |
Fixed-Combination Olmesartan/Amlodipine Was Superior to Perindopril + Amlodipine in Reducing Central Systolic Blood Pressure in Hypertensive Patients With Diabetes.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Tetrazoles; Treatment Outcome | 2016 |
Comparative study of the efficacy of olmesartan/amlodipine vs. perindopril/amlodipine in peripheral blood pressure after missed dose in type 2 diabetes.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Perindopril; Tetrazoles; Treatment Outcome | 2016 |
Olmesartan Combined With Amlodipine on Oxidative Stress Parameters in Type 2 Diabetics, Compared With Single Therapies: A Randomized, Controlled, Clinical Trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Aryldialkylphosphatase; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Isoprostanes; Male; Oxidative Stress; Peroxidase; Tetrazoles | 2016 |
Comparative Study of the Efficacy of Olmesartan/Amlodipine vs. Perindopril/Amlodipine in Peripheral and Central Blood Pressure Parameters After Missed Dose in Type 2 Diabetes.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Pulse Wave Analysis; Tetrazoles | 2016 |
Adherence to triple-component antihypertensive regimens is higher with single-pill than equivalent two-pill regimens: A randomized controlled trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome | 2021 |
Effects of olmesartan and amlodipine on blood pressure, endothelial function, and vascular inflammation.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Essential Hypertension; Humans; Hypertension; Inflammation; Middle Aged | 2023 |
The effects of Olmesartan/amlodipine administered in the Morning or At Night on nocturnal blood pressure reduction in Chinese patients with mild-moderate essential hypertension (OMAN Trial): study protocol for a prospective, multicenter, randomized, open-
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; East Asian People; Essential Hypertension; Humans; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic | 2023 |
42 other study(ies) available for olmesartan and amlodipine
| Article | Year |
|---|---|
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Olmesartan, but not amlodipine, improves endothelium-dependent coronary dilation in hypertensive patients.
Topics: Adult; Amlodipine; Blood Chemical Analysis; Cohort Studies; Coronary Circulation; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Positron-Emission Tomography; Probability; Prospective Studies; Risk Assessment; Tetrazoles; Treatment Outcome; Vasodilation | 2007 |
Two amlodipine/ARB combinations for hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.
Topics: Adolescent; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biological Availability; Calcium Channel Blockers; Clinical Trials, Phase I as Topic; Drug Combinations; Drug Interactions; Humans; Imidazoles; Middle Aged; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Therapeutic Equivalency; Young Adult | 2008 |
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Drug Synergism; Femoral Artery; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neuropeptides; Nifedipine; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima | 2009 |
Re: Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Dosage Forms; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2009 |
Stability indicating LC method for the simultaneous determination of amlodipine and olmesartan in dosage form.
Topics: Acetonitriles; Amlodipine; Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Stability; Hydrolysis; Imidazoles; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tetrazoles | 2010 |
Improving quality of life in hypertension management using a fixed-dose combination of olmesartan and amlodipine in primary care.
Topics: Aged; Amlodipine; Antihypertensive Agents; Diastole; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Quality of Life; Surveys and Questionnaires; Systole; Tetrazoles | 2010 |
[Fixed drug combinations in hypertension: a budget impact analysis for the Spanish Health System on the marketing of a fixed combination of olmesartan/amlodipine].
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Costs and Cost Analysis; Decision Trees; Drug Combinations; Humans; Hypertension; Imidazoles; Middle Aged; National Health Programs; Spain; Tetrazoles | 2011 |
The 'pyrrhic victory' of amlodipine over hydrochlorothiazide in the OLAS Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Comorbidity; Drug Therapy, Combination; Endpoint Determination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Life Style; Metabolic Syndrome; Tetrazoles; Treatment Outcome | 2011 |
The effect of antihypertensive agents in people at high risk of cardiovascular disease and diabetes: a view through smoke and mirrors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Risk Factors; Tetrazoles; Treatment Outcome | 2011 |
Efficacy of Sevikar® compared to the combination of perindopril plus amlodipine on central arterial blood pressure in patients with moderate-to-severe hypertension: Rationale and design of the SEVITENSION study.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Calcium Channel Blockers; Confidence Intervals; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Renin-Angiotensin System; Research Design; Severity of Illness Index; Tetrazoles | 2011 |
Efficacy of amlodipine and olmesartan medoxomil in hypertensive patients with diabetes and obesity.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Prospective Studies; Tetrazoles | 2011 |
[Case of olmesartan and amlodipine intoxication].
Topics: Acid-Base Imbalance; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Calcium Gluconate; Drug Overdose; Female; Humans; Hypotension; Imidazoles; Middle Aged; Norepinephrine; Tetrazoles; Treatment Outcome; Water-Electrolyte Imbalance | 2011 |
[Hypertension: improved therapy adherence after switch to a fixed drug combinations].
Topics: Amlodipine; Antihypertensive Agents; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Substitution; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Tetrazoles | 2012 |
Hypertension in older adults: progress and limitations.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
[Modern hypertension treatment. More than effective blood pressure reduction].
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles | 2012 |
Clinical and economic outcomes associated with amlodipine/renin-angiotensin system blocker combinations.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Insurance Claim Review; Linear Models; Male; Medication Adherence; Middle Aged; Renin-Angiotensin System; Retrospective Studies; Tetrazoles; Treatment Outcome | 2013 |
Olmesartan-based therapies: an effective way to improve blood pressure control and cardiovascular protection.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles; Treatment Failure | 2013 |
[Hypertension. Goal: achieving target blood pressure with only 1 pill daily].
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles | 2013 |
Effect of azelnidipine and amlodipine on single cell mechanics in mouse cardiomyocytes.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Animals; Azetidinecarboxylic Acid; Biomechanical Phenomena; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Imidazoles; Mechanical Phenomena; Mice; Myocytes, Cardiac; Single-Cell Analysis; Tetrazoles | 2013 |
Simultaneous determination of olmesartan and amlodipine in human plasma and urine by ultra performance liquid chromatography tandem mass spectrometry.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Humans; Imidazoles; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrazoles | 2013 |
[Dynamics the level of visfatin and markers of immune inflammation in hypertensive patients with abdominal obesity using the combination of antihypertensive therapy].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Imidazoles; Immune System Diseases; Inflammation; Interleukin-4; Lipid Metabolism; Nicotinamide Phosphoribosyltransferase; Obesity, Abdominal; Tetrazoles | 2013 |
ARB-based single-pill platform to guide a practical therapeutic approach to hypertensive patients.
Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Risk Factors; Tablets; Tetrazoles; Treatment Outcome | 2014 |
Clinical impact of patient adherence to a fixed-dose combination of olmesartan, amlodipine and hydrochlorothiazide.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Tetrazoles; Young Adult | 2014 |
[Hypertension. Guidelines recommend fixed combinations].
Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Randomized Controlled Trials as Topic; Tetrazoles | 2014 |
If I had resistant hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome | 2014 |
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan | 2015 |
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles | 2015 |
Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome | 2015 |
[Optimizing antihypertensive therapy].
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Randomized Controlled Trials as Topic; Tetrazoles | 2015 |
Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods.
Topics: Amlodipine; Calibration; Dosage Forms; Drug Combinations; Hydrochlorothiazide; Imidazoles; Least-Squares Analysis; Spectrophotometry; Tetrazoles | 2016 |
Patient Adherence to Olmesartan/Amlodipine Combinations: Fixed Versus Extemporaneous Combinations.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Tetrazoles | 2016 |
Blood Pressure Reduction is Associated With the Changes in Oxidative Stress and Endothelial Activation in Hypertension, Regardless of Antihypertensive Therapy.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Oxidative Stress; Tetrazoles; Vitamins | 2016 |
Efficacy of olmesartan amlodipine in Colombian hypertensive patients (soat study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Colombia; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome | 2017 |
Single-Pill Triple Fixed Dose Combination Therapy with Single Component Drug Monitoring in Treatment-Resistant Hypertension: A Pilot Study.
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Substitution; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Pilot Projects; Tablets; Tetrazoles; Time Factors; Treatment Outcome | 2018 |
Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Mineralocorticoid Receptor Antagonists; Ramipril; Tetrazoles | 2018 |
Efficacy and safety of a combination antihypertensive drug (olmesartan plus azelnidipine): "Issues with hypertension studies in real-world practice".
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Combinations; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2020 |
Involvement of Angiotensin II Type 1 Receptor and Calcium Channel in Vascular Remodeling and Endothelial Dysfunction in Rats with Pressure Overload.
Topics: Amlodipine; Animals; Calcium Channels; Carotid Artery Injuries; Constriction, Pathologic; Disease Models, Animal; Hyperplasia; Imidazoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha; Vascular Remodeling | 2020 |
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hypertension; Imidazoles; Liquid-Liquid Extraction; Metoprolol; Patient Compliance; Pilot Projects; Plasma; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles | 2021 |
Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Hypertension and Cardiovascular Risk Factors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Female; Heart Disease Risk Factors; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Prospective Studies; Republic of Korea; Risk Factors; Tetrazoles | 2023 |