Page last updated: 2024-09-04

olmesartan and amlodipine

olmesartan has been researched along with amlodipine in 103 studies

Compound Research Comparison

Studies
(olmesartan)
Trials
(olmesartan)
Recent Studies (post-2010)
(olmesartan)
Studies
(amlodipine)
Trials
(amlodipine)
Recent Studies (post-2010) (amlodipine)
8411855544,2001,5041,671

Protein Interaction Comparison

ProteinTaxonomyolmesartan (IC50)amlodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.2
Potassium channel subfamily K member 2Homo sapiens (human)0.4
Alpha-2A adrenergic receptorHomo sapiens (human)0.602
Alpha-2C adrenergic receptorHomo sapiens (human)1.8
5-hydroxytryptamine receptor 6Homo sapiens (human)2.898
Sodium-dependent dopamine transporter Homo sapiens (human)5.521
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)2.7
Potassium channel subfamily K member 2 Bos taurus (cattle)0.43

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (11.65)29.6817
2010's83 (80.58)24.3611
2020's8 (7.77)2.80

Authors

AuthorsStudies
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Fujii, S; Furumoto, T; Katoh, C; Morita, K; Naya, M; Tamaki, N; Tsukamoto, T; Tsutsui, H1
Oparil, S; Pimenta, E1
Allison, M; Bathala, MS; Haworth, S; Heyrman, R; Lee, J; Noveck, R; Rohatagi, S; Rubets, I; Salazar, DE; Shenouda, M1
Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I; Tomono, Y1
Pimenta, E1
Ansari, A; Braun, N; Handrock, R; Klebs, S; Ulmer, HJ1
Chavanu, KJ; Dubiel, R; Rosendorff, C; Xu, J1
Futai, R; Ito, T; Kawanishi, Y; Kitaura, Y; Terasaki, F1
Vivencio, B1
Kawahira, K; Matsumoto, S; Miyata, R; Shimodozono, M1
Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohira, M; Oyama, T; Saiki, A; Shirai, K; Yamaguchi, T1
Dohi, Y; Kimura, G; Miyagawa, K; Nakazawa, A; Sato, K; Sugiura, T; Yamashita, S1
Chrysant, SG; Heyrman, R; Karki, S; Lee, J; Melino, M1
Corradi, L; Derosa, G; Fogari, R; Malamani, G; Mugellini, A; Preti, P; Zoppi, A1
Dubiel, R; Kereiakes, DJ; Maa, JF; Neutel, JM; Punzi, H; Shojaee, A; Waverczak, WF1
Patil, KR; Rane, VP; Sangshetti, JN; Shinde, DB; Yeole, RD1
Hoshino, A; Matsubara, H; Nakamura, T1
Ferrario, CM; Smith, RD1
Bramlage, P; Erdlenbruch, W; Fronk, EM; Ketelhut, R; Schmieder, RE; Stuhr, T; Wolf, WP1
Bilo, G; Hoshide, S; Lonati, L; Ochoa, JE; Parati, G; Ramos, C1
Bramlage, P; Erdlenbruch, W; Fronk, EM; Ketelhut, R; Schmieder, RE; Stuhr, T; Wasem, J; Wolf, WP1
Comi-Diaz, C; Martinez-Martin, FJ; Pedrianes-Martin, P; Peiro-Martinez, I; Rodriguez-Rosas, H; Soriano-Perera, P1
Alvarez-Martín, C; Belén Ferro-Rey, M; de Salas-Cansado, M; Roca-Cusachs, A; Sicras-Mainar, A1
Makris, T; Stefanadis, C; Thomopoulos, C; Tsioufis, C1
McInnes, GT1
Kreutz, R1
Ruilope, LM; Schaefer, A1
Ando, K; Fujita, T; Haneda, M; Ito, S; Kashihara, N; Kishimoto, J; Nangaku, M; Node, K; Shimosawa, T1
Graff, A; Hsueh, WA; Jones, CJ; Littlejohn, TJ; Nesbitt, SD; Neutel, JM; Qian, C; Shojaee, A; Waverczak, WF; Weir, MR1
Maa, JF; Punzi, H; Shojaee, A; Waverczak, WF1
Saito, Y; Takami, T2
Narkiewicz, K1
Ideno, S; Kobari, M; Nakada, T; Oiwa, T; Yaguchi, A1
Axthelm, C; Kaiser, E; Meister, F; Sieder, C1
Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn Iii, T; Melino, M; Oparil, S1
Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A1
Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn, T; Melino, M; Oparil, S2
Arakawa, K; Jinnouchi, H; Jinnouchi, T; Kim-Mitsuyama, S; Matsui, K; Ogawa, H2
Daikuhara, H; Ishida, T; Kikuchi, F1
Maa, JF; Neutel, J; Shojaee, A1
Rich, MW1
Adachi, H; Hoshizaki, H; Kasama, S; Kawaguchi, R; Koyama, K; Murakami, J; Oshima, S; Sato, C; Toyama, T; Yamashita, E1
Ammentorp, B; Christian Rump, L; Laeis, P; Volpe, M1
Carbone, A; Cicero, AF; D'Angelo, A; Derosa, G; Fogari, E; Maffioli, P; Querci, F5
Paneni, F; Passerini, J; Tocci, G; Volpe, M1
Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H1
Buzinec, P; Ferrario, CM; Panjabi, S; Swindle, JP1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
de la Sierra, A; Volpe, M1
Hou, CJ; Hsia, CH; Lai, WT; Lin, TH; Pan, JP; Tsai, CD; Tsai, JP1
Di Renzo, G; Izzo, R; Manzi, MV; Marino, M; Rozza, F; Santoro, M; Trimarco, B; Trimarco, V1
Iribe, G; Ito, H; Kaihara, K; Naruse, K1
Hu, P; Jiang, J; Qi, W; Zhao, Q1
Chrysant, SG1
Bramlage, P; Fimmers, R; Gansz, A; Lüders, S; Nadal, J; Schmieder, RE; Schrader, J; Sturm, CD; Zemmrich, C2
Ruilope, L; Schaefer, A1
Andreeva, AA1
de la Sierra, A; Kreutz, R; Laurent, S; Manolis, AJ; Volpe, M1
Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Smolnik, R; Wolf, WP; Zemmrich, C1
Ammentorp, B; de la Sierra, A; Laeis, P; Volpe, M1
Bilo, G; Hoshide, S; Koch, W; Parati, G1
O'Brien, E1
Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H1
Ammentorp, B; de la Sierra, A; Kreutz, R; Laeis, P1
Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A1
Ott, C; Raff, U; Schmieder, RE; Schneider, MP; Walker, S1
Bramlage, P; Fronk, EM; Schmieder, RE; Smolnik, R; Sutton, G; Wolf, WP1
Schlimpert, V1
Ahn, Y; Bae, JH; Jung, HW; Kang, DH; Kim, CH; Kim, KI; Park, CG1
Brazier, JE; Guest, JF; Haag, U; Marques da Silva, P; Soro, M1
Ruilope, LM1
Pichler, G; Redon, J2
Abdelhameed, AS; Bakheit, AH; Darwish, HW1
Cricelli, C; Cricelli, I; Lapi, F; Levi, M; Parretti, D; Pasqua, A; Piccinni, C1
D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM1
Drenjancevic, I; Mihalj, M; Rucevic, S; Tadzic, R; Vcev, A1
Buendia, R; Zambrano, M1
Douros, A; Kreutz, R; Scholze, J1
Armario, P; Banegas, JR; de la Cruz, JJ; de la Sierra, A; Gorostidi, M; Oliveras, A; Ruilope, LM; Segura, J; Vinyoles, E1
Okamura, K; Shirai, K; Takamiya, Y; Urata, H; Yano, Y1
Chen, DR; Chen, J; Gao, PJ; Han, WQ; Jiang, H; Ruan, CC1
Ahn, KT; Cho, BR; Kim, BJ; Kim, DK; Lee, SY; Lee, WS; Park, JI; Sung, J1
Lauder, L; Mahfoud, F; Meyer, MR; Vollmer, AC; Wagmann, L1
Burnier, M; Redon, J; Volpe, M1
Abe, T; Bekki, M; Fukumoto, Y; Honda, A; Igata, S; Kurata, S; Maeda-Ogata, S; Matsui, T; Nishino, Y; Sugiyama, Y; Tahara, A; Tahara, N; Yamagishi, SI1
Hong, JH; Hyun, D; Kim, GH; Kim, HL; Kim, W; Lim, S; Min, KW; Oh, J; Park, SD; Shin, J1
Chen, X; Jia, S; Li, X; Liao, H; Liu, K; Liu, X; Meng, Q; Shi, R; Sun, L; Wang, S; Wang, Z; Xu, M; Ye, R; Zhang, X; Zhang, Z1

Reviews

10 review(s) available for olmesartan and amlodipine

ArticleYear
Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination.
    Vascular health and risk management, 2008, Volume: 4, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Drug Combinations; Humans; Hypertension; Imidazoles; Patient Compliance; Tablets; Tetrazoles

2008
Olmesartan/Amlodipine: combination therapy for the treatment of hypertension [corrected].
    Advances in therapy, 2009, Volume: 26, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Combinations; Humans; Hypertension; Imidazoles; Medication Adherence; Tetrazoles

2009
Role of olmesartan in combination therapy in blood pressure control and vascular function.
    Vascular health and risk management, 2010, Sep-07, Volume: 6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Vessels; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tetrazoles

2010
Efficacy and tolerability of olmesartan/amlodipine combination therapy in patients with mild-to-severe hypertension: focus on 24-h blood pressure control.
    Therapeutic advances in cardiovascular disease, 2010, Volume: 4, Issue:5

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Severity of Illness Index; Tetrazoles

2010
Olmesartan/amlodipine: a review of its use in the management of hypertension.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Evidence-Based Medicine; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome

2011
Angiotensin II receptor blocker combinations: from guidelines to clinical practice.
    Blood pressure, 2012, Volume: 21, Issue:2

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Practice Guidelines as Topic; Tetrazoles

2012
Triple combination therapy to improve blood pressure control: experience with olmesartan-amlodipine-hydrochlorothiazide therapy.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:18

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles

2012
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan

2013
Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD.
    Expert review of cardiovascular therapy, 2013, Volume: 11, Issue:9

    Topics: Age Factors; Amlodipine; Cardiovascular Diseases; Diabetes Complications; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Renal Insufficiency, Chronic; Tetrazoles

2013
Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2023, Volume: 30, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Olmesartan Medoxomil

2023

Trials

51 trial(s) available for olmesartan and amlodipine

ArticleYear
Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
    Current medical research and opinion, 2009, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Patient Compliance; Prospective Studies; Tetrazoles; Valine; Valsartan

2009
Comparison of olmesartan medoxomil versus amlodipine besylate on regression of ventricular and vascular hypertrophy.
    The American journal of cardiology, 2009, Aug-01, Volume: 104, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome

2009
Olmesartan ameliorates myocardial function independent of blood pressure control in patients with mild-to-moderate hypertension.
    Heart and vessels, 2009, Volume: 24, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Echocardiography, Doppler, Color; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Inflammation; Male; Middle Aged; Myocardium; Severity of Illness Index; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Function, Left

2009
Benefits of the angiotensin II receptor antagonist olmesartan in controlling hypertension and cerebral hemodynamics after stroke.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:11

    Topics: Acetazolamide; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Circulation; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Stroke; Stroke Rehabilitation; Tetrazoles; Tomography, X-Ray Computed; Treatment Outcome; Young Adult

2009
Effects of olmesartan, an angiotensin II receptor blocker, and amlodipine, a calcium channel blocker, on Cardio-Ankle Vascular Index (CAVI) in type 2 diabetic patients with hypertension.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Ankle; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Deoxyguanosine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypertension; Imidazoles; Lipids; Male; Middle Aged; Tetrazoles

2009
Renoprotective effect of calcium channel blockers in combination with an angiotensin receptor blocker in elderly patients with hypertension. A randomized crossover trial between benidipine and amlodipine.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:1

    Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Renal Insufficiency, Chronic; Tetrazoles

2010
Efficacy and tolerability of amlodipine plus olmesartan medoxomil in patients with difficult-to-treat hypertension.
    Journal of human hypertension, 2010, Volume: 24, Issue:11

    Topics: Age Factors; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; United States; Vasodilator Agents

2010
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients.
    Advances in therapy, 2010, Volume: 27, Issue:1

    Topics: Adult; Aged; Amlodipine; Ankle Joint; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Norepinephrine; Prospective Studies; Tetrazoles; Valine; Valsartan

2010
Efficacy of amlodipine and olmesartan medoxomil in patients with hypertension: the AZOR Trial Evaluating Blood Pressure Reductions and Control (AZTEC) study.
    Therapeutic advances in cardiovascular disease, 2010, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; United States; Vasodilator Agents

2010
The bedtime administration ameliorates blood pressure variability and reduces urinary albumin excretion in amlodipine-olmesartan combination therapy.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Albumins; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Creatinine; Drug Chronotherapy; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome

2010
Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice.
    Vascular health and risk management, 2010, Sep-07, Volume: 6

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome

2010
Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.
    Journal of human hypertension, 2011, Volume: 25, Issue:6

    Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Comorbidity; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Vascular Cell Adhesion Molecule-1

2011
Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:4

    Topics: Adult; Aged; Albuminuria; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Middle Aged; Research Design; Sympatholytics; Tetrazoles

2011
A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Self Report; Tetrazoles; Titrimetry; Young Adult

2011
Effects of Azelnidipine plus OlmesaRTAn versus amlodipine plus olmesartan on central blood pressure and left ventricular mass index: the AORTA study.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Ultrasonography

2011
Efficacy and tolerability of the single-pill combination of aliskiren 300 mg/amlodipine 10 mg in hypertensive patients not controlled by olmesartan 40 mg/amlodipine 10 mg.
    Current medical research and opinion, 2012, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Resistance; Drug Substitution; Female; Fumarates; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Young Adult

2012
24-hour efficacy and safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors

2011
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:5

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2012
Long-term efficacy and safety of triple-combination therapy with olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide for hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:3

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors

2012
Angiotensin II receptor blocker-based therapy in Japanese elderly, high-risk, hypertensive patients.
    The American journal of medicine, 2012, Volume: 125, Issue:10

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Single-Blind Method; Survival Analysis; Tetrazoles; Treatment Outcome

2012
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
    Diabetes & vascular disease research, 2012, Volume: 9, Issue:4

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome

2012
Efficacy of amlodipine/olmesartan ± hydrochlorothiazide in patients uncontrolled on prior calcium channel blocker or angiotensin II receptor blocker monotherapy.
    Advances in therapy, 2012, Volume: 29, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Comorbidity; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles

2012
Triple-Combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: the TRINITY randomized, double-blind, 12-week, parallel-group study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Aug-01, Volume: 12, Issue:4

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles

2012
Olmesartan improves coronary flow reserve of hypertensive patients using coronary magnetic resonance imaging compared with amlodipine.
    Cardiology, 2012, Volume: 122, Issue:4

    Topics: Adenosine; Adult; Aged; Amlodipine; Antihypertensive Agents; Coronary Circulation; Echocardiography; Female; Humans; Hypertension; Imidazoles; Magnetic Resonance Angiography; Male; Middle Aged; Stroke Volume; Tetrazoles; Vasodilator Agents; Ventricular Function, Left

2012
Efficacy and safety of triple antihypertensive therapy with the olmesartan/amlodipine/hydrochlorothiazide combination.
    Clinical drug investigation, 2012, Oct-01, Volume: 32, Issue:10

    Topics: Adult; Aged; Aging; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Young Adult

2012
Olmesartan/amlodipine combination versus olmesartan or amlodipine monotherapies on blood pressure and insulin resistance in a sample of hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles; Treatment Outcome

2013
Effects of an olmesartan/amlodipine fixed dose on blood pressure control, some adipocytokines and interleukins levels compared with olmesartan or amlodipine monotherapies.
    Journal of clinical pharmacy and therapeutics, 2013, Volume: 38, Issue:1

    Topics: Adipokines; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Interleukins; Male; Middle Aged; Tetrazoles; Time Factors

2013
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Efficacy and tolerability between an olmesartan/amlodipine fixed-dose combination and an amlodipine double dose in mild to moderate hypertension.
    The Kaohsiung journal of medical sciences, 2013, Volume: 29, Issue:5

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome

2013
Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2013, Volume: 20, Issue:1

    Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chi-Square Distribution; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Female; Humans; Hypertension; Hypoglycemic Agents; Imidazoles; Italy; Male; Medication Adherence; Middle Aged; Monte Carlo Method; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome

2013
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Diastole; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness; Ventricular Function, Left

2013
Evaluation of safety and efficacy of a fixed olmesartan/amlodipine combination therapy compared to single monotherapies.
    Expert opinion on drug safety, 2013, Volume: 12, Issue:5

    Topics: Adipokines; Amlodipine; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin; Insulin Resistance; Interleukin-10; Interleukin-8; Lipids; Male; Middle Aged; Tetrazoles

2013
Results from a 12 months, randomized, clinical trial comparing an olmesartan/amlodipine single pill combination to olmesartan and amlodipine monotherapies on blood pressure and inflammation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Jan-23, Volume: 51

    Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles

2014
Different aspects of sartan + calcium antagonist association compared to the single therapy on inflammation and metabolic parameters in hypertensive patients.
    Inflammation, 2014, Volume: 37, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Inflammation; Insulin Resistance; Lipids; Male; Middle Aged; Tetrazoles

2014
Daytime systolic ambulatory blood pressure with a direct switch between candesartan monotherapy and the fixed-dose combination olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-1).
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:11

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Systole; Tetrazoles; Treatment Outcome

2013
The fixed-dose combination of olmesartan/amlodipine was superior in central aortic blood pressure reduction compared with perindopril/amlodipine: a randomized, double-blind trial in patients with hypertension.
    Advances in therapy, 2013, Volume: 30, Issue:12

    Topics: Adult; Aged; Amlodipine; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Multivariate Analysis; Perindopril; Risk Assessment; Tetrazoles; Treatment Outcome

2013
Daytime systolic ambulatory blood pressure with a two-step switch from candesartan to olmesartan monotherapy and the fixed-dose combination of olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-2).
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; White People

2014
Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Risk Factors; Sex Factors; Tetrazoles; Treatment Outcome

2014
Open-label study assessing the long-term efficacy and safety of triple olmesartan/amlodipine/hydrochlorothiazide combination therapy for hypertension.
    Advances in therapy, 2014, Volume: 31, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time; Treatment Outcome

2014
Efficacy of olmesartan/amlodipine combination therapy in reducing ambulatory blood pressure in moderate-to-severe hypertensive patients not controlled by amlodipine alone.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:9

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Retreatment; Tetrazoles; Treatment Outcome

2014
Efficacy and tolerability of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide: a subgroup analysis of patients stratified by hypertension severity, age, sex, and obesity.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:10

    Topics: Adult; Age Factors; Aged; Amlodipine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Sex Factors; Tetrazoles

2014
Olmesartan improves pulse wave velocity and lowers central systolic blood pressure and ambulatory blood pressure in patients with metabolic syndrome.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:2

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Hemodynamics; Humans; Imidazoles; Male; Metabolic Syndrome; Middle Aged; Pulse Wave Analysis; Tetrazoles; Treatment Outcome; Vascular Stiffness

2015
A multicenter, non-comparative study to evaluate the efficacy and safety of fixed-dose olmesartan/amlodipine in Korean patients with hypertension who are naïve or non-responders to anti-hypertensive monotherapy (ACE-HY study).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:6

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Prospective Studies; Republic of Korea; Tetrazoles; Treatment Outcome

2015
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension.
    Health and quality of life outcomes, 2015, Feb-21, Volume: 13

    Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Quality of Life; Tetrazoles; Treatment Outcome

2015
Fixed-Combination Olmesartan/Amlodipine Was Superior to Perindopril + Amlodipine in Reducing Central Systolic Blood Pressure in Hypertensive Patients With Diabetes.
    Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Tetrazoles; Treatment Outcome

2016
Comparative study of the efficacy of olmesartan/amlodipine vs. perindopril/amlodipine in peripheral blood pressure after missed dose in type 2 diabetes.
    Journal of hypertension, 2016, Volume: 34, Issue:2

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Perindopril; Tetrazoles; Treatment Outcome

2016
Olmesartan Combined With Amlodipine on Oxidative Stress Parameters in Type 2 Diabetics, Compared With Single Therapies: A Randomized, Controlled, Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:13

    Topics: Adult; Amlodipine; Antihypertensive Agents; Aryldialkylphosphatase; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Isoprostanes; Male; Oxidative Stress; Peroxidase; Tetrazoles

2016
Comparative Study of the Efficacy of Olmesartan/Amlodipine vs. Perindopril/Amlodipine in Peripheral and Central Blood Pressure Parameters After Missed Dose in Type 2 Diabetes.
    American journal of hypertension, 2016, Volume: 29, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Pulse Wave Analysis; Tetrazoles

2016
Adherence to triple-component antihypertensive regimens is higher with single-pill than equivalent two-pill regimens: A randomized controlled trial.
    Clinical and translational science, 2021, Volume: 14, Issue:3

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome

2021
Effects of olmesartan and amlodipine on blood pressure, endothelial function, and vascular inflammation.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023, Volume: 30, Issue:4

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Essential Hypertension; Humans; Hypertension; Inflammation; Middle Aged

2023
The effects of Olmesartan/amlodipine administered in the Morning or At Night on nocturnal blood pressure reduction in Chinese patients with mild-moderate essential hypertension (OMAN Trial): study protocol for a prospective, multicenter, randomized, open-
    Trials, 2023, Nov-28, Volume: 24, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; East Asian People; Essential Hypertension; Humans; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic

2023

Other Studies

42 other study(ies) available for olmesartan and amlodipine

ArticleYear
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Olmesartan, but not amlodipine, improves endothelium-dependent coronary dilation in hypertensive patients.
    Journal of the American College of Cardiology, 2007, Sep-18, Volume: 50, Issue:12

    Topics: Adult; Amlodipine; Blood Chemical Analysis; Cohort Studies; Coronary Circulation; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Positron-Emission Tomography; Probability; Prospective Studies; Risk Assessment; Tetrazoles; Treatment Outcome; Vasodilation

2007
Two amlodipine/ARB combinations for hypertension.
    The Medical letter on drugs and therapeutics, 2007, Dec-17, Volume: 49, Issue:1276

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biological Availability; Calcium Channel Blockers; Clinical Trials, Phase I as Topic; Drug Combinations; Drug Interactions; Humans; Imidazoles; Middle Aged; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Therapeutic Equivalency; Young Adult

2008
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
    American journal of hypertension, 2009, Volume: 22, Issue:2

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Drug Synergism; Femoral Artery; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neuropeptides; Nifedipine; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima

2009
Re: Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
    Current medical research and opinion, 2009, Volume: 25, Issue:9

    Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Dosage Forms; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan

2009
Stability indicating LC method for the simultaneous determination of amlodipine and olmesartan in dosage form.
    Journal of chromatographic science, 2010, Volume: 48, Issue:7

    Topics: Acetonitriles; Amlodipine; Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Stability; Hydrolysis; Imidazoles; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tetrazoles

2010
Improving quality of life in hypertension management using a fixed-dose combination of olmesartan and amlodipine in primary care.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:17

    Topics: Aged; Amlodipine; Antihypertensive Agents; Diastole; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Quality of Life; Surveys and Questionnaires; Systole; Tetrazoles

2010
[Fixed drug combinations in hypertension: a budget impact analysis for the Spanish Health System on the marketing of a fixed combination of olmesartan/amlodipine].
    Atencion primaria, 2011, Volume: 43, Issue:7

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Costs and Cost Analysis; Decision Trees; Drug Combinations; Humans; Hypertension; Imidazoles; Middle Aged; National Health Programs; Spain; Tetrazoles

2011
The 'pyrrhic victory' of amlodipine over hydrochlorothiazide in the OLAS Study.
    Journal of human hypertension, 2011, Volume: 25, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Comorbidity; Drug Therapy, Combination; Endpoint Determination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Life Style; Metabolic Syndrome; Tetrazoles; Treatment Outcome

2011
The effect of antihypertensive agents in people at high risk of cardiovascular disease and diabetes: a view through smoke and mirrors.
    Journal of human hypertension, 2011, Volume: 25, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Risk Factors; Tetrazoles; Treatment Outcome

2011
Efficacy of Sevikar® compared to the combination of perindopril plus amlodipine on central arterial blood pressure in patients with moderate-to-severe hypertension: Rationale and design of the SEVITENSION study.
    Contemporary clinical trials, 2011, Volume: 32, Issue:5

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Calcium Channel Blockers; Confidence Intervals; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Renin-Angiotensin System; Research Design; Severity of Illness Index; Tetrazoles

2011
Efficacy of amlodipine and olmesartan medoxomil in hypertensive patients with diabetes and obesity.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Prospective Studies; Tetrazoles

2011
[Case of olmesartan and amlodipine intoxication].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2011, Volume: 24, Issue:3

    Topics: Acid-Base Imbalance; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Calcium Gluconate; Drug Overdose; Female; Humans; Hypotension; Imidazoles; Middle Aged; Norepinephrine; Tetrazoles; Treatment Outcome; Water-Electrolyte Imbalance

2011
[Hypertension: improved therapy adherence after switch to a fixed drug combinations].
    MMW Fortschritte der Medizin, 2012, Mar-22, Volume: 154, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Substitution; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Tetrazoles

2012
Hypertension in older adults: progress and limitations.
    The American journal of medicine, 2012, Volume: 125, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles

2012
[Modern hypertension treatment. More than effective blood pressure reduction].
    MMW Fortschritte der Medizin, 2012, Nov-15, Volume: 154, Issue:20

    Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles

2012
Clinical and economic outcomes associated with amlodipine/renin-angiotensin system blocker combinations.
    Therapeutic advances in cardiovascular disease, 2013, Volume: 7, Issue:1

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Insurance Claim Review; Linear Models; Male; Medication Adherence; Middle Aged; Renin-Angiotensin System; Retrospective Studies; Tetrazoles; Treatment Outcome

2013
Olmesartan-based therapies: an effective way to improve blood pressure control and cardiovascular protection.
    Journal of hypertension, 2013, Volume: 31 Suppl 1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles; Treatment Failure

2013
[Hypertension. Goal: achieving target blood pressure with only 1 pill daily].
    MMW Fortschritte der Medizin, 2013, Apr-04, Volume: 155, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles

2013
Effect of azelnidipine and amlodipine on single cell mechanics in mouse cardiomyocytes.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Animals; Azetidinecarboxylic Acid; Biomechanical Phenomena; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Imidazoles; Mechanical Phenomena; Mice; Myocytes, Cardiac; Single-Cell Analysis; Tetrazoles

2013
Simultaneous determination of olmesartan and amlodipine in human plasma and urine by ultra performance liquid chromatography tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Nov-01, Volume: 938

    Topics: Amlodipine; Chromatography, High Pressure Liquid; Humans; Imidazoles; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrazoles

2013
[Dynamics the level of visfatin and markers of immune inflammation in hypertensive patients with abdominal obesity using the combination of antihypertensive therapy].
    Georgian medical news, 2013, Issue:225

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Imidazoles; Immune System Diseases; Inflammation; Interleukin-4; Lipid Metabolism; Nicotinamide Phosphoribosyltransferase; Obesity, Abdominal; Tetrazoles

2013
ARB-based single-pill platform to guide a practical therapeutic approach to hypertensive patients.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2014, Volume: 21, Issue:2

    Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Risk Factors; Tablets; Tetrazoles; Treatment Outcome

2014
Clinical impact of patient adherence to a fixed-dose combination of olmesartan, amlodipine and hydrochlorothiazide.
    Clinical drug investigation, 2014, Volume: 34, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Tetrazoles; Young Adult

2014
[Hypertension. Guidelines recommend fixed combinations].
    MMW Fortschritte der Medizin, 2014, Apr-17, Volume: 156, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Randomized Controlled Trials as Topic; Tetrazoles

2014
If I had resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome

2014
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:3

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan

2015
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles

2015
Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice.
    Vascular health and risk management, 2015, Volume: 11

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome

2015
[Optimizing antihypertensive therapy].
    MMW Fortschritte der Medizin, 2015, Feb-19, Volume: 157, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Randomized Controlled Trials as Topic; Tetrazoles

2015
Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Volume: 66, Issue:1

    Topics: Amlodipine; Calibration; Dosage Forms; Drug Combinations; Hydrochlorothiazide; Imidazoles; Least-Squares Analysis; Spectrophotometry; Tetrazoles

2016
Patient Adherence to Olmesartan/Amlodipine Combinations: Fixed Versus Extemporaneous Combinations.
    Journal of managed care & specialty pharmacy, 2016, Volume: 22, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Tetrazoles

2016
Blood Pressure Reduction is Associated With the Changes in Oxidative Stress and Endothelial Activation in Hypertension, Regardless of Antihypertensive Therapy.
    Kidney & blood pressure research, 2016, Volume: 41, Issue:6

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Oxidative Stress; Tetrazoles; Vitamins

2016
Efficacy of olmesartan amlodipine in Colombian hypertensive patients (soat study).
    BMC research notes, 2017, Apr-26, Volume: 10, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Colombia; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome

2017
Single-Pill Triple Fixed Dose Combination Therapy with Single Component Drug Monitoring in Treatment-Resistant Hypertension: A Pilot Study.
    Current vascular pharmacology, 2018, 01-26, Volume: 16, Issue:2

    Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Substitution; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Pilot Projects; Tablets; Tetrazoles; Time Factors; Treatment Outcome

2018
Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension.
    Journal of hypertension, 2018, Volume: 36, Issue:7

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Mineralocorticoid Receptor Antagonists; Ramipril; Tetrazoles

2018
Efficacy and safety of a combination antihypertensive drug (olmesartan plus azelnidipine): "Issues with hypertension studies in real-world practice".
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Jul-03, Volume: 42, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Combinations; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome

2020
Involvement of Angiotensin II Type 1 Receptor and Calcium Channel in Vascular Remodeling and Endothelial Dysfunction in Rats with Pressure Overload.
    Current medical science, 2020, Volume: 40, Issue:2

    Topics: Amlodipine; Animals; Calcium Channels; Carotid Artery Injuries; Constriction, Pathologic; Disease Models, Animal; Hyperplasia; Imidazoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha; Vascular Remodeling

2020
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
    Molecules (Basel, Switzerland), 2021, Mar-09, Volume: 26, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hypertension; Imidazoles; Liquid-Liquid Extraction; Metoprolol; Patient Compliance; Pilot Projects; Plasma; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles

2021
Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Hypertension and Cardiovascular Risk Factors.
    Advances in therapy, 2023, Volume: 40, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Female; Heart Disease Risk Factors; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Prospective Studies; Republic of Korea; Risk Factors; Tetrazoles

2023