olivomycins and fluoroboric-acid

olivomycins has been researched along with fluoroboric-acid* in 1 studies

Other Studies

1 other study(ies) available for olivomycins and fluoroboric-acid

Article	Year
Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I. Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14 The azo coupling of the antibiotic olivomycin I (1) with aryl diazonium tetrafluoroborates produced 5-aryldiazenyl-6-O-deglycosyl derivatives of 1. The structures of new compounds were confirmed by (1)H NMR and mass spectrometry analysis. A quantum-chemical study was performed to analyze the possible directions of electrophilic substitution of 1 and the easiness of 6-O-disaccharide hydrolysis in the course of azo coupling. The antiproliferative and anti-retroviral activities of novel derivatives were studied. Topics: Animals; Antibiotics, Antineoplastic; Borates; Boric Acids; Cell Line, Tumor; Cell Proliferation; Diazonium Compounds; Humans; Microbial Sensitivity Tests; Molecular Structure; Olivomycins; Viruses	2009

Article

Year

Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I.

Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

The azo coupling of the antibiotic olivomycin I (1) with aryl diazonium tetrafluoroborates produced 5-aryldiazenyl-6-O-deglycosyl derivatives of 1. The structures of new compounds were confirmed by (1)H NMR and mass spectrometry analysis. A quantum-chemical study was performed to analyze the possible directions of electrophilic substitution of 1 and the easiness of 6-O-disaccharide hydrolysis in the course of azo coupling. The antiproliferative and anti-retroviral activities of novel derivatives were studied.

Topics: Animals; Antibiotics, Antineoplastic; Borates; Boric Acids; Cell Line, Tumor; Cell Proliferation; Diazonium Compounds; Humans; Microbial Sensitivity Tests; Molecular Structure; Olivomycins; Viruses

2009