oleylamide has been researched along with tert-amyl-alcohol* in 1 studies
1 other study(ies) available for oleylamide and tert-amyl-alcohol
Article | Year |
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Economically pertinent continuous amide formation by direct lipase-catalyzed amidation with ammonia.
An economically pertinent process for the lipase-catalyzed synthesis of amides was developed. A continuous plug flow reactor was used. The model reaction was the production of oleamide, a lubricant and anti-slip agent, via direct Candida antarctica lipase B-catalyzed amidation of oleic acid with ammonia. Of all solvents tested, 2-methyl-2-butanol was found to respond optimally to the demands formulated in our specifications. A continuous conversion of oleic acid into oleamide of 85% was obtained. A productivity of 4.5 tons oleamide per kg of enzyme per year was calculated, indicating a contribution of enzyme to the product price of only 4%. The volumetric productivity, 100 g. L(-1). h(-1), is 4 to 100 times higher than in literature procedures. A simple crystallization procedure leads to 99% purity. Topics: Amides; Ammonia; Butanols; Catalysis; Computer Simulation; Enzymes, Immobilized; Europe; Fungal Proteins; Lipase; Models, Chemical; Oleic Acid; Oleic Acids; Pentanols; Pilot Projects; Solvents; United States | 2003 |