Page last updated: 2024-08-21

oleanolic acid and ursolic acid

oleanolic acid has been researched along with ursolic acid in 386 studies

Research

Studies (386)

TimeframeStudies, this research(%)All Research%
pre-19906 (1.55)18.7374
1990's24 (6.22)18.2507
2000's98 (25.39)29.6817
2010's217 (56.22)24.3611
2020's41 (10.62)2.80

Authors

AuthorsStudies
Cosentino, LM; Fujioka, T; Hu, CQ; Ikeshiro, Y; Kashiwada, Y; Kitanaka, S; Kozuka, M; Lee, KH; Nagao, T; Okabe, H; Wang, HK; Yamagishi, T; Yasuda, I; Yeh, E1
Bohlin, L; Noreen, Y; Perera, P; Ringbom, T; Segura, L1
Deng, JZ; Hecht, SM; Starck, SR1
Cosentino, LM; Hashimoto, A; Ikeshiro, Y; Kashiwada, Y; Lee, KH; Nagao, T; Okabe, H1
Hata, K; Hori, K; Takahashi, S1
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Mahapatra, A; Mallavadhani, UV; Manjula, C; Raja, SS1
Khan, SI; Master, HE; Poojari, KA1
Johnson, RK; Kingston, DG; Prakash Chaturvedula, VS; Schilling, JK1
Chen, X; Ishibashi, M; Li, Y; Ohizumi, Y; Oshima, Y; Satake, M1
Andriantsiferana, R; Cao, S; Guza, RC; Kingston, DG; Miller, JS; Rasamison, VE1
Franzblau, SG; Gu, JQ; Montenegro, G; Timmermann, BN; Wang, Y1
Ando, M; Fu, L; Hasegawa, T; Hirose, K; Kataoka, T; Kiuchi, M; Li, N; Mitsui, T; Oka, S; Sakai, J; Wang, J; Zhang, S; Zhao, M1
Topçu, G1
Ali, Z; Ferreira, D; Khan, IA; Khan, SI; Pawar, RS1
Baba, K; Bastow, KF; Itokawa, H; Lee, KH; Morris-Natschke, SL; Nakagawa-Goto, K; Taniguchi, M; Tatsuzaki, J1
Habib-Jiwan, JL; Hoet, S; Muccioli, GG; Opperdoes, FR; Pieters, L; Quetin-Leclercq, J1
Boumediene, K; Da Nascimento, S; Dassonville-Klimpt, A; Galéra, P; Gnoatto, SC; Gosmann, G; Moslemi, S; Sonnet, P1
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Barda, Y; Kisselev, OG; Marshall, GR; Taylor, CM1
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Dao, TT; Kim, WG; Lee, CH; Lee, SJ; Nguyen, PH; Oh, WK; Thuong, PT1
Chadwick, LR; Franzblau, SG; Jaki, BU; Lankin, DC; Pauli, GF; Wang, Y; Zhang, F1
Amano, F; Hamashima, Y; Hasegawa, J; Kajimoto, T; Katoh, K; Node, M; Takebe, Y; Tanaka, R; Tsujii, H; Yamada, T1
Hao, J; Liu, J; Lu, Q; Sheng, H; Sun, H; Zhang, L; Zhang, P1
Bae, K; Ha, do T; Ngoc, TM; Nhiem, NX; Thu, NB; Tuan, DT; Yim, N1
Auwerx, J; Boudjelal, G; Genet, C; Lobstein, A; Saladin, R; Schmidt, C; Schoonjans, K; Souchet, M; Strehle, A; Wagner, A1
Acebey-Castellon, IL; Bouthagane, N; Doan Thi Mai, H; Gangloff, SC; Hung, NV; Lavaud, C; Le Magrex Debar, E; Litaudon, M; Muhammad, D; Roseau, N; Sevenet, T; Voutquenne-Nazabadioko, L1
Chen, J; Chen, L; Cheng, K; Gong, Y; Hao, J; Jiang, H; Li, H; Li, L; Liang, Z; Liu, H; Liu, J; Luo, C; Sun, H; Wen, X; Zhang, L; Zhang, P; Zhang, X; Zheng, M; Zhu, X1
Camici, G; Estrada-Soto, S; López-Martínez, S; López-Vallejo, F; Medina-Franco, JL; Navarrete-Vázquez, G; Ortiz-Andrade, R; Paoli, P; Ramírez-Espinosa, JJ; Rios, MY1
Chau, MV; Doan, HT; Fong, HH; Franzblau, SG; Nguyen, CM; Nguyen, HT; Nguyen, HV; Pham, CV; Soejarto, DD; Truong, NB; Zhang, HJ1
El-Kabbani, O; Endo, S; Hara, A; Iinuma, M; Matsunaga, T; Soda, M; Tajima, K; Takemura, M; Zhao, HT1
Gatbonton-Schwager, TN; Letterio, JJ; Tochtrop, GP1
Chin, YW; Jee, JG; Jeong, YJ; Keum, YS; Kim, Y; Lee, J; Lee, JM; Yu, MS1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Chen, K; Huang, X; Peng, Y; Qiu, Y; Shi, Y; Sun, D; Wang, H; Wang, Q; Xiao, S; Yu, F; Yu, M; Zhang, C; Zhang, L; Zhang, Z; Zhao, C; Zheng, Y; Zhou, D; Zhu, L1
Feng, Y; Mei, Z; Wang, C; Yang, G; Yang, J; Yang, X; Zhao, P; Zhou, Q1
Cai, L; Jiang, S; Jiang, X; Li, J; Li, X; Liang, G; Liu, K; Lu, L; Na, H; Wang, C; Wang, Q; Xu, X; Yu, F; Zhang, T; Zhang, Z; Zheng, B1
Ba Thi, C; D'hooghe, M; Dang Thi, TA; Doan Duy, T; Kim Tuyet, NT; Pham The, C; Thanh Nguyen, H; Van Nguyen, T1
Hao, X; Huang, L; Li, Q; Luo, H; Wang, D; Yang, X; Zhang, J1
Csuk, R; Heller, L; Köwitsch, A; Perl, V; Schwarz, S; Siewert, B1
Camelio, AM; Cho, J; Claussen, KR; DiGiovanni, J; Nelson, AT; Siegel, D; Tremmel, L1
Feng, B; Hou, XY; Shi, JJ; Zhang, CL; Zhao, CH; Zhao, LX1
Cao, CY; Gao, JM; Wei, J; Yin, X; Zhang, CC; Zhang, Q1
Ahn, HC; Cho, SC; Choi, BY; Fei, X; Keum, YS; Kim, HJ; Lee, K; Seo, SY1
Csuk, R; Heller, L; Wiemann, J1
Bastida, J; da Silva, GN; da Silva, MV; Gnoatto, SC; Lopes, NP; Macedo, AJ; Silva, DB; Silva, NL; Tasca, T; Vieira, Pde B1
Csuk, R; Heller, L; Kuhfs, J; Sommerwerk, S1
Chun, KH; Kim, J; Kim, Y; Lim, JW; Yoon, Y1
Li, H; Tian, S; Wang, C; Wei, X; Wu, P; Xu, L; Xue, J1
Csuk, R; Heller, L; Kerzig, C; Kramell, AE; Sommerwerk, S1
Bailon-Moscoso, N; Castillo-Veintimilla, P; Romero-Benavides, JC; Ruano, AL; Silva-Rivas, R; Vivanco-Jaramillo, S1
Alcaro, S; Corona, A; Cottiglia, F; Distinto, S; Floris, C; Fois, B; Maccioni, E; Malpure, NV; Meleddu, R; Sonar, VP; Tramontano, E1
Chau, VM; Do Thi, T; Doan Thi Mai, H; Litaudon, M; Nguyen, TT; Nguyen, VH; Pham, VC; Truong, BN1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Cao, G; Chang, Y; Chen, D; He, X; Huang, X; Liu, J; Luo, H; Ni, S; Shen, Q; Sun, H; Wang, P; Wen, X; Zhou, H1
Dong, YS; Sun, WL; Wen, C; Xing, Y; Xiu, ZL; Yu, XX; Zhang, BW1
Baikova, IP; Giniyatullina, GV; Kataev, VE; Kazakova, OB; Lopatina, TV; Medvedeva, NI; Smirnova, IE1
Huang, H; Li, Z; Liu, R; Min, Q; Zhu, Q; Zhu, Y1
Anaya-Eugenio, GD; Burdette, JE; Chai, HB; Czarnecki, AA; de Blanco, EJC; Kinghorn, AD; Ninh, TN; Ren, Y; Soejarto, DD; Yuan, C1
Efdi, M; Itoh, T; Katsurayama, K; Koketsu, M; Ninomiya, M1
Appendino, G; Bellido, ML; Calzado, MA; Caprioglio, D; Cruz, C; Galera, N; Jinénez, C; Minassi, A; Muñoz, E; Prados, ME; Rogati, F1
Gao, X; Kang, H; Li, B; Liu, N; Liu, S; Liu, T; Liu, X; Long, X; Lu, C; Peng, J; Qi, M; Qin, S; Sun, T; Wei, M; Wei, Y; Xie, M; Xu, Z; Yang, C; Yang, G; Zhang, Z; Zhao, R; Zhou, H; Zhu, L1
Borkova, L; Hodon, J; Kazakova, A; Pokorny, J; Urban, M1
Ansari, MI; Coop, A; Johnson, CR; Kamil Hussain, M; Khatoon, S; Saquib, M1
Deng, Y; Li, CH; Wu, T; Zhai, SQ1
Cheng, KG; Huang, JY; Liu, CM; Sheng, LX; Wen, XA1
Brandes, B; Csuk, R; Fischer, L; Hoenke, S1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Buckle, R; Eldridge, GR; Ellis, M; Garo, E; Hu, JF; Huang, Z; Lawrence, JA; Norman, VL; Rathinavelu, S; Starks, CM; Williams, RB1
Awale, S; Dibwe, DF; Kim, MJ; Omar, AM; Sun, S; Tawila, AM; Toyooka, N; Ueda, JY1
Ge, GB; Li, YC; Lin, S; Song, YQ; Tian, GH; Xia, GY; Zhang, JF; Zhong, WC1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Amodeo, P; Appendino, G; Avonto, C; De Petrocellis, L; Del Prete, D; Moriello, AS; Vitale, RM1
Feng, F; Liu, Y; Lu, X; Qiao, Y; Qin, N; Qu, W; Sun, H1
Daelemans, D; De Jonghe, S; Dehaen, W; Hu, H; Krasniqi, B; Li, Y; Luyten, W; Persoons, L; Wang, R1
Hansen, PR; Kjaerulff, L; Kongstad, KT; Liang, C; Staerk, D1
Chen, Y; Shang, S1
Balanehru, S; Nagarajan, B2
Shi, Y; Wang, H1
Kametaka, S; Kohda, H; Kozai, K; Miyake, Y; Nagasaka, N; Suginaka, H; Yamasaki, K1
Ito, Y; Koshimizu, K; Ohigashi, H; Takamura, H; Tokuda, H1
Ito, Y; Koshimizu, K; Ohigashi, H; Tokuda, H1
Chung, HY; Kim, KW; Lee, HY; Sohn, KH; Yi, SY; Young, HS1
Hayashi, H; Kito, H; Nagase, H; Niikawa, M; Sato, T1
Li, CK; Su, Z; Wang, HB; Zhang, ZY; Zia, ZX1
Chung, HY; Kim, KH; Kim, KW; Lee, HY; Lee, JJ1
Inada, A; Murata, H; Nakanishi, T; Somekawa, M; Tanaka, K1
Besterman, JM; Chen, J; Kinghorn, AD; Lee, IS; Lee, S; Leitner, P; Pezzuto, JM; Tan, GT1
Liu, J2
Hsu, HY; Lin, CC; Yang, JJ1
Han, SK; Jin, IJ; Kim, YM; Ko, YI; Park, SJ1
Giner, RM; Máñez, S; Recio, MC; Ríos, JL1
Barchowsky, A; Benoit, NE; Finlay, HJ; Gribble, GW; Honda, T; Nathan, C; Sporn, MB; Suh, N; Williams, C; Xie, QW1
Farina, C; Pifferi, G; Pinza, M1
Chung, HY; Chung, JK; Jeon, SS; Kim, KW; Kim, ND; Lee, KH; Paik, KJ1
Kirby, GC; Simmonds, MS; Steele, JC; Warhurst, DC1
Cert, A; Pérez-Camino, MC1
Hammond, GB; Kingston, DG; Neto, CC; Vaisberg, AJ; Zhou, BN1
Kim, YK; Ryu, SY; Yoon, SK1
Han, G; Lu, X; Shen, J; Xu, W1
Jha, RN; Pandey, MB; Pandey, VB; Upadhyay, RK1
Aquino, R; Della Loggia, R; Fkih-Tetouani, S; Ilidrissi, A; Ismaili, H; Sosa, S; Tortora, S; Tubaro, A1
Guo, WJ; Li, J; Yang, QY1
Bore, L; Gribble, GW; Honda, T1
Aquino, RP; Brkic, D; Fkih-Tetouani, S; Ilidrissi, A; Ismaili, H; Sosa, S; Touati, D; Tubaro, A1
Ding, L; Yan, H; Zhao, L; Zhu, D1
Anis, I; Khan, PM; Malik, A; Riaz, N; Shah, R1
del Carmen Montes-Horcasitas, M; Flores-Sánchez, IJ; Ortega-López, J; Ramos-Valdivia, AC1
Gui, MY; Jin, YR; Wang, BZ1
Ding, A; Feng, Y; Zhang, L1
Chen, L; Cheng, L; Liu, Y; Luo, J1
Nadar, A; Ramnanan, P; Shode, FO; Somova, LI1
Nadar, A; Rammanan, P; Shode, FO; Somova, LO1
An, DK; Cheng, Z; Hang, TJ; Xie, Y; Zhang, ZX1
Baglin, I; Cavé, C; Lacaille-Dubois, MA; Mitaine-Offer, AC; Nour, M; Tan, K1
Gao, N; Kawashima, A; Miyata, N; Morimoto, S; Murakami, S; Saito, M; Saito, S; Sugawara, K; Yang, J; Yoshimura, H; Zhang, X1
Chen, WS; Jia, XM; Lou, ZY; Qiao, CZ; Zhang, WD1
PARKS, LM; WU, BY1
Kuttan, G; Raphael, TJ1
BRIESKORN, CH; HOFMANN, H1
Liu, H; Shi, Y; Wang, D; Yang, G; Yu, A; Zhang, H1
Mipando, M; Shode, FO; Somova, LI1
Bérangère, C; Caussarieu, N; Lafosse, M; Morin, P; Morin-Allory, L1
Jamil, K; Mahapatra, A; Mallavadhani, UV; Reddy, PS1
Becker, H; Hostanska, K; Scher, JM; Urech, K1
Chai, Y; Liu, C; Lou, Z; Qi, Y; Wu, X; Zhang, G1
Li, H; Li, ML; Yang, B; Zhao, YX1
Guo, QL; Yang, JS1
Gören, AC; Kingston, DG; Kökdil, G; Topçu, G; Zhou, BN1
Cerda-García-Rojas, CM; Feria-Romero, I; Lazo, E; Ponce-Noyola, T; Ramos-Valdivia, AC1
Chen, J; Liu, Y; Shu, J; Shu, R1
Kim, SH; Lee, HK; Lee, SH; Nam, GW1
Im, KR; Jeong, TS; Lee, WS; Park, YD; Sung, ND1
Cipak, L; Grausova, L; Miadokova, E; Novotny, L; Rauko, P1
Chen, GL; Cheng, DL; Xie, JM; Zhang, JG; Zhang, YH1
Aparecida Resende, F; Cunha, WR; da Silva Faria, MC; de Andrade Barcala, CA; Kato, FH; Tavares, DC1
Baniahmad, A; Matusch, R; Papaioannou, M; Schleich, S1
Kozics, K; Ovesná, Z; Slamenová, D1
Chandramohan, G; Pugalendi, KV; Senthil, S1
Chiari, E; Filho, JD; Leite, JP; Lombardi, JA; Oliveira, AB1
Jiang, S; Li, Y; Liu, X; Yang, P1
Bi, KS; Chen, XH; Liao, QF; Xie, SP1
Heo, HJ; Kang, SS; Kim, C; Kim, YH; Kim, YS; Lee, CJ; Lee, HJ; Park, YC; Seo, UK; Seok, JH1
Kowalski, R1
Fujimoto, Y; Hosoi, K; Iida, T; Ikeda, N; Makino, M; Ogawa, S1
Li, GC; Wang, DY; Wu, JY1
Chen, K; Chen, Q; Li, X; Sun, C; Zhang, W; Zhou, C1
Chen, G; Chen, T; Huang, L; Ye, Z1
Wójciak-Kosior, M1
Chang, CS; Chang, YS; Chao, DC; Chen, JC; Ho, TY; Hsiang, CY; Li, CC; Wu, SL1
Chan, KC; Yin, MC1
De la Puerta Vazquez, R; García Gimenez, MD; Saenz Rodriguez, MT; Santos Rosa, C1
Ahn, SK; Bak, H; Hong, SP; Jeong, SW; Kim, B; Lee, SH; Lim, SW; Ryoo, HC1
Lei, LD; Tu, PF; Xie, GB; Zhou, SX1
Cáceres-Castillo, D; Cedillo-Rivera, R; Mena-Rejón, GJ; Quijano, L1
Liang, SW; Wang, R; Wang, SM; Weng, QF; Xu, GW1
ORR, JE; ROWE, EJ1
Bremner, JB; Chokchaisiri, R; Suksamrarn, A; Tanachatchairatana, T1
Jang, DS; Kim, JH; Kim, JM; Kim, JS; Kim, YS; Lee, YM; Yoo, JL1
Araújo, FR; Castro, MB; Cunha, WR; Furtado, MA; Furtado, RA; Oliveira, WL; Rodrigues, EP; Tavares, DC1
Da Nascimento, S; Dalla Vechia, L; Dassonville-Klimpt, A; Gnoatto, SC; Gosmann, G; Guillon, J; Lencina, CL; Mossalayi, D; Sonnet, P1
Hao, J; Sun, H; Wen, X; Zhang, P1
Tsai, SJ; Yin, MC1
Duval, RE; Finance, C; Fontanay, S; Grare, M; Mayer, J1
Liu, C; Liu, H; Xiong, Y; Xu, W; Yang, X; Zeng, S1
Kao, TC; Shyu, MH; Yen, GC2
Arnason, JT; Awad, R; Durst, T; Muhammad, A; Trudeau, VL1
Chen, J; Li, WL; Lv, H; Zhang, HQ1
Exarchou, V; Gerothanassis, IP; Kontogianni, VG; Troganis, A1
Dai, WS; Fu, QG; Li, ZJ; Yu, WW1
Aguilera, MP; Allouche, Y; Beltrán, G; Gaforio, JJ; Jiménez, A; Uceda, M1
Kang, W; Song, Y; Zhang, L1
Jäger, S; Kopp, T; Laszczyk, MN; Scheffler, A; Trojan, H1
Chang, FR; Chen, IH; Chen, SL; Chen, YH; Du, YC; Hung, CS; Lu, MC; Wu, CC; Wu, YC; Yen, MH1
Lee, MS; Thuong, PT1
Ahmad, AS; Mansour, AI; Nafady, AM; Ramadan, MA1
Li, R; Liu, DF; Quan, P; Wei, FD; Xu, QW; Zhang, Q1
Grudniak, AM; Janiszowska, W; Klicka, A; Kurek, A; Popowska, M; Samluk, L; Szwed, M; Wolska, KI1
Hsu, CC; Huang, CN; Wang, ZH; Yin, MC1
Huang, CY; Wu, ST; Yan, SL; Yin, MC1
Guo, T; Li, Y; Wang, J; Wang, P1
Beracochea, D; Feuillere, N; Ibarra, A; Lesburgere, E; Roller, M1
Fang, X; Wang, J; Yu, X; Zhang, G; Zhao, J1
Cui, M; Liu, S; Liu, Z; Song, F; Yan, C; Yu, Z; Zhang, H1
Ho, CT; Juliani, HR; Pan, MH; Park, CH; Shen, D; Simon, JE; Wu, QL2
Fang, L; Lin, N; Wu, Y1
Ishii, H; Masuda, K; Nakane, T; Takada, K1
Christensen, SB; Hansen, EW; Jäger, AK; Moesby, L; Saaby, L1
Barker, J; Carew, M; Ganbold, M; Jones, L; Ma, R1
Andrade e Silva, ML; Cunha, WR; Da Silva Filho, AA; da Silva, R; de Matos, GX; Martins, CH; Souza, MG; Tozatti, MG1
Cehn, YS; Zhang, JH; Zhang, K; Zhao, SQ1
Sheng, Y; Tao, J; Wang, Z; Zhao, D; Zhou, C1
Bonfim-Melo, A; Corbett, CE; de Toyama, DO; dos Grecco, SS; Fávero, OA; Lago, JH; Laurenti, MD; Passero, LF; Romoff, P; Toyama, MH; Zalewsky, CA1
Gong, W; Guo, Q; Wu, X; Zhou, L1
Cao, YK; Chai, L; Deng, GH; Li, YB; Lin, CZ; Zhang, CX; Zhao, ZX; Zhu, CC1
Chen, YS; Lin, XY; Xie, JM; Yao, H; Zhang, YH1
Chan, CY; Huang, CY; Lin, CC; Mong, MC; Yin, MC1
Ahmed, S; Bishayee, A; Brankov, N; Perloff, M1
Bau, DT; Chang, YH; Chen, YC; Kuo, CL; Lee, HZ; Tsai, RY1
Grudniak, AM; Kurek, A; Szarlak, J; Wolska, KI1
Chang, CI; Hsu, JL; Liao, MH; Lin, BW; Lin, PY; Shih, WL; Wu, HY; Yen, CH; Yu, FL1
Li, G; Song, C; Sun, Z; Suo, Y; Xia, L; You, J; Zhang, X1
Hu, Y; Lv, S; Sheng, Y; Tao, J; Zhang, Y; Zhao, D; Zhou, C1
Albuquerque, S; Andrade E Silva, ML; Cassio Sola Veneziani, R; Crotti, AE; Cunha, WR; da Silva Filho, AA; Dos Santos, FF; Gimenez, VM; Groppo, M; Januário, AH; Magalhães, LG; Peixoto, JA1
Li, GL; Song, CH; Suo, YR; Xia, L; You, JM; Zheng, J1
Cho, K; Lee, CJ; Lee, HJ; Lee, MN; Lee, SY; Seok, JH; Woo, H1
Chen, Q; Chen, Z; Zhang, W; Zhang, Y1
Liang, G; Sheng, Y; Tao, J; Zhao, D; Zhou, C1
Guo, Q; Wang, Y; Xiao, Y; Yin, J1
Bi, Y; Liu, Y; Shen, J; Wang, Z; Xiao, W; Zhang, Q1
Li, MH; Wang, XQ; Wu, G; Zhang, N; Zhou, CJ1
Ruan, SQ; Shan, JZ; Sun, M; Xuan, YY1
Araya, JJ; Hagenbuch, B; Roth, M; Timmermann, BN1
Hernández-Ortega, S; Marrero, JG; Mena-Rejón, GJ; Miranda, LD; Rivero-Chan, BE1
Li, HB; Song, Y; Wang, BW; Xia, EQ; Xu, XR; Zhu, L1
Li, SZ; Song, QS; Xu, XY; Yang, XH1
Guo, H; Liu, H; Wang, C; Zhang, B1
Cárdenas, J; Escárcega-Bobadilla, MV; Estrada-Reyes, R; Frontana-Uribe, BA; Morales-Serna, JA; Salmón, M1
Fukushima, EO; Mizutani, M; Muranaka, T; Ohyama, K; Ono, E; Saito, K; Seki, H; Umemoto, N1
Chaves, MH; Ferreira, EL; Gomes, BS; Oliveira, FA; Oliveira, JP; Silva, LL; Sousa-Neto, BP1
Baggio, CH; da Silva, CF; das Neves, TL; Horst, H; Kanazawa, LK; Pizzolatti, MG; Rodrigues, MR; Santos, AR; Werner, MF1
Nielsen, CH; Saaby, L1
Deng, GF; Guo, YJ; Li, HB; Xia, EQ; Xu, XR; Yu, YY1
Andò, S; Barone, I; Bonofiglio, D; Catalano, S; Gelsomino, L; Giordano, C; Gu, G; Menichini, F; Statti, G1
Coombes, PH; Crouch, NR; Haque, S; Mohammed, AM; Mulholland, DA; Pohjala, LL; Tammela, PS1
Donica, H; Matysik-Woźniak, A; Niedziela, P; Paduch, R; Wójciak-Kosior, M1
Kurek, A; Nadkowska, P; Pliszka, S; Wolska, KI1
Gao, L; Lin, CZ; Zhao, ZX; Zhu, CC1
Chang, CD; Liao, MH; Lin, PY; Shih, WL; Wu, HY; Yu, FL1
Chen, Y; Guo, Q; Zhang, L; Zhu, Z1
Chang, YS; Ho, YL; Lai, SC; Liao, CR; Peng, WH1
Chen, Y; Guo, Q; Liu, L; Wang, C1
Chieng, YC; Hoon, LS; Hsum, YW; Mooi, LY; Soo, KK; Yew, WT1
Huang, L; Li, C; Li, J; Liu, B; Wang, H; Ye, H; Zhang, Y1
Bid, HK; Chakravarti, B; Konwar, R; Maurya, R; Rajendran, SM; Siddiqui, JA; Yadav, PP1
Pradeep, T; Sarkar, D; Srimany, A1
He, X; Hu, H; Wang, Y; Zhang, Z1
Agiomyrgianaki, A; Dais, P1
David, JM; David, JP; e Silva, Mde L; Fontana, R; Lima, LS; Reis, PS; Santos, RA; Silva, LC1
Chen, Y; Guo, Q; Zhang, L; Zhang, X; Zhu, Z1
Chen, W; Chen, Y; Ding, Y; Lv, X; Zhang, P; Zhou, L1
Bruni, R; Caligiani, A; Malavasi, G; Marseglia, A; Palla, G; Tognolini, M1
Çulhaoğlu, B; Dirmenci, T; Topçu, G; Yapar, G1
Cai, YF; Huang, QS1
Fang, X; Kong, L; Li, S; Liao, Q; Sun, R; Wang, J; Wu, X; Zhang, Q; Zhang, Y; Zhu, X; Zhu, Y1
Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; do Prado Júnior, JC; e Silva, ML; Esperandim, VR; Kuehn, CC; Toldo, MP1
Chen, S; Huang, L; Jiang, X; Wu, L1
Chen, Y; Qin, MJ; Wang, GK; Wu, C1
Alguraan, Z; Banihani, S; Swedan, S1
Kong, LY; Luo, J; Wang, JS; Wang, ZW1
Chen, JC; Lin, XJ; Liu, TT; Min, QX; Wan, LS1
Chen, Y; Guo, Q; Yu, M; Zhang, L; Zhu, Z1
Castro-Mussot, ME; Cornejo-Garrido, J; Hernández-Pando, R; Jiménez-Arellanes, A; López-García, S; Luna-Herrera, J; Marquina, B; Mata-Espinosa, D; Meckes-Fischer, M; Torres, J1
Han, LF; Liu, EW; Wang, Q; Zhang, Y1
Campos, BL; Corbett, CE; Grecco, Sdos S; Lago, JH; Laurenti, MD; Passero, LF; Yamamoto, ES1
Kong, LB; Liu, HJ; Sun, RN; Wang, J; Zhang, YN1
Csuk, R; Köwitsch, A; Siewert, B; Wiemann, J1
Singh, NK; Singh, VP1
Ding, F; Jiang, YT; Peng, W; Peng, YK1
Chiu, HF; Huang, TC; Wei, MC; Yang, YC1
Han, YY; Shi, ZM; Wang, PY; Wang, XJ; Wu, XR; Xue, XW1
Bley, T; Geib, D; Haas, C; Kümmritz, S; Pavlov, AI; Steingroewer, J; Ulber, R1
Camer, D; Huang, XF; Szabo, A; Yu, Y1
Borcan, F; Coricovac, D; Crăiniceanu, Z; Danciu, C; Dehelean, CA; Munteanu, M; Oprean, C; Soica, C; Trandafirescu, C1
Fu, L; Gribble, GW; Liby, KT; Lin, QX; Sporn, MB1
El-Halawany, AM; Kandil, ZA; Ma, Q; Salah El Dine, R1
Chan, T; Cheung, FS; Li, Z; Wang, K; Zheng, J; Zhou, F; Zhu, L1
Grudniak, AM; Janiszowska, W; Kurek, A; Markowska, K; Wolska, KI1
Dong, S; Gao, R; Guo, M; Ni, J; Wang, L; Yang, Y; Zhao, L1
Feng, B; Xu, J; Zhang, YQ; Zhao, CH; Zhao, LX1
Lei, P; Men, X; Zhang, W1
He, QQ; Ma, CM; Ma, JN; Yang, L; Zhang, JY1
Broniatowski, M; Flasiński, M; Mastalerz, P1
Chen, XL; Fang, ZJ; Mei, QX; Zhou, HB; Zhu, YX1
Gleńsk, M; Gliński, JA; Stefanowicz, P; Włodarczyk, M1
Fornari, T; García-Risco, MR; Reglero, G; Riebesehl, N; Sheldon, J; Steinmann, E; Vázquez, E1
Chen, G; Hu, N; Li, G; Liu, D; Liu, S; Suo, Y; Wu, H; You, J1
Gaikwad, NB; Kshirsagar, PR; Nimbalkar, MS; Pai, SR1
Abrego, G; Alvarado, HL; Calpena, AC; Clares, B; García, ML; Garduño-Ramirez, ML2
Chai, Y; Li, W; Li, Y; Lv, L; Wang, X; Xu, H; Zhang, G; Zhao, L1
Efferth, T; Kadioglu, O1
Bianco, A; Nicoletti, M; Serafini, M; Venditti, A1
Broniatowski, M; Flasiński, M; Fontaine, P; Wydro, P1
Abrego, G; Alvarado, HL; Calpena, AC; Clares, B; García, ML; Garduño-Ramirez, ML; Souto, EB1
Gao, Y; Lin, S; Song, G; Yuan, Y1
Ashour, A; Katakura, Y; Shimizu, K; Tan, H1
Baranauskaitė, J; Bernatonienė, J; Drakšienė, G; Ivanauskas, L; Jakštas, V; Kopustinskienė, DM; Masteikova, R1
Joshi, SP; Khedkar, VM; Kulkarni, RR; Puranik, VG; Sarkar, D; Shurpali, K1
Lv, Y; Olsson, ME; Tahir, II1
Ahn, SJ; Kook, JK; Park, SN1
Castañeda-Sanchez, JI; Castro-Mussot, ME; Domínguez-López, L; Hernández-Sanchéz, J; Jiménez-Arellanes, A; López-García, S; Luna-Herrera, J1
Kim, TP; Mai, TP; Phi, PN1
Huang, GQ; Li, B; Lu, RM; Wei, JH; Zhong, ZG1
Ji, ZY; Wang, CH; Yan, FL; Yang, YX; Zhuang, FF1
Campos, BL; Jesus, JA; Kallás, EG; Lago, JH; Laurenti, MD; Levy, D; Passero, LF; Rafael-Fernandes, M; Ribeiro, SP; Santos-Gomes, G; Sessa, DP; Silva, MS; Yamamoto, ES1
Duan, JA; Guo, S; Qian, DW; Zhu, SQ1
Claude, B; Morin, P; Nehmé, R; Syntia, F1
Bley, T; Delenk, H; Gantz, S; Haas, C; Kümmritz, S; Louis, M; Oehmichen, F; Steingroewer, J; Steudler, S1
Luo, P; Pan, W; Su, J; Wei, J; Wei, W; Zhu, Y1
Bah, M; Chamorro-Cevallos, GA; Chávez, MI; García-Rodríguez, RV; Garduño-Siciliano, L; Gutiérrez-Rebolledo, GA; Jiménez-Arellanes, MA; Pérez-González, MZ; Siordia-Reyes, GA1
Hegde, HV; Joshi, RK; Kholkute, SD; Pai, SR; Upadhya, V1
Ambrus, R; Bojin, F; Borcan, F; Danciu, C; Dehelean, C; Minorics, R; Muntean, D; Oprean, C; Paunescu, V; Pinzaru, IA; Soica, C; Tanasie, G; Zambori, C; Zupko, I1
Fu, HZ; Yan, QW; Zhang, TX; Zhong, RJ; Zhou, GP1
Gao, YS; Lin, SQ; Song, G; Yuan, Y1
Chen, X; Gao, W; Huang, H; Li, X; Mao, X; Miao, J; Wang, T; Zhao, C1
Kashyap, D; Punia, S; Sharma, A; Sharma, AK; Tuli, HS1
Ambrus, R; Bojin, F; Cristea, M; Csányi, E; Danciu, C; Dehelean, C; Ivan, A; Mioc, M; Oprean, C; Paunescu, V; Soica, C; Tatu, C1
Huang, S; Liu, D; Liu, M; Wu, J; Xia, C; Xie, H; Xiong, Y; Zhang, H1
Brodelius, PE; Guo, M; Lu, X; Wang, Y1
Cao, J; Peng, LQ; Xu, JJ1
Günther, G; Morales, J; Rodríguez, L; Valdés, K1
Hayes, T; Ross, SA; Srivedavyasasri, R1
Feng, Z; Lee, ES; Liu, X; Sun, J; Tian, T; Zhao, C; Zhao, L1
Coovadia, Y; Khedr, MA; Nwaeze, KU; Odhav, B; Pillay, M; Shode, F; Singh, A; Venugopala, KN1
Chen, YY; He, XX; Huang, YY; Luo, HB; Peng, GT; Tan, BX; Wu, YN; Yang, L; Yu, S1
González-Chávez, MM; Pérez-González, C; Pérez-Gutiérrez, S; Ramos-Velázquez, CS; Sánchez-Mendoza, E; Serrano-Vega, R1
Dong, S; Gao, W; Li, X; Sun, J; Wu, Y; Zhao, H1
Hai, NT; Kariyazono, H; Long, DD; Nakajima, K; Ohta, T; Oiso, S; Shoyama, Y; Tung, NH; Uto, T1
Ahn, SJ; Bang, IS; Cho, E; Choi, MH; Kim, JM; Kook, JK; Lim, YK; Park, SN1
Bojin, F; Caunii, A; Cristea, M; Drăghia, L; Ivan, A; Oprean, C; Paunescu, V; Soica, C; Tatu, C1
Beaufay, C; Bero, J; Hérent, MF; Quetin-Leclercq, J1
Ding, H; Gong, D; Hu, X; Xu, X; Zhang, G1
Avram, S; Caunii, A; Cristea, M; Danciu, C; Dehelean, C; Ivan, A; Marti, D; Oprean, C; Paunescu, V; Soica, C; Spandidos, DA; Susan, R; Tatu, C; Tsatsakis, A; Tzanakakis, G1
Henao, IC; Pereañez, JA; Preciado, LM; Rey-Suárez, P1
Catteau, L; Nizet, V; Olson, J; Pinho, MG; Quetin-Leclercq, J; Reichmann, NT; Van Bambeke, F1
Ren, T; Xu, Z1
Alvarado, HL; Calpena, AC; Clares, B; Garduño-Ramírez, ML; Melguizo, C; Ortiz, R; Prados, JC1
Bui, TD; Dang, VS; Mai, DT; Ngo, QL; Ngo, TN; Nguyen, TP; Pham, NKT; Phan, NM; Tran, CL; Vo, CT1
Dirmenci, T; Erim, FB; Kalaycıoğlu, Z; Uzaşçı, S1
Adams, CM; Ebert, SM; Murry, DJ; Murry, LT; Stebounova, L1
Csuk, R; Serbian, I1
Balcells, M; Canela-Garayoa, R; Cubero, MÁ; Delpino-Rius, A; Eras, J; Llovera, M; Marsol-Vall, A1
Nie, Y; Yao, W1
Cao, S; Lachcik, PJ; Wastney, ME; Weaver, CM; Wong, MS; Xiao, HH1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1
Kai, H; Matsuno, K; Mutoh, J; Nakamura, S; Nakashima, K; Tojoh, Y; Wada, M1
Araya, H; Ferhat, M; Fujimoto, Y; Kabouchea, Z1
Al-Halabi, Z; Al-Harrasi, A; Csuk, R; Köwitsch, A; Loesche, A; Lucas, SD; Sippl, W1
Li, P; Li, Y; Lin, H; Liu, A; Liu, Z; Xiao, W; Yuan, B; Zhang, S1
Cheng, YD; Lan, WC; Lee, SC; Lin, LW; Tsai, FH; Wu, CR1
Adewole, KE; Ishola, AA1
Cui, H; Jin, C; Jin, M; Li, G; Wang, J; Wang, R; Ye, C; Zhou, W; Zhou, Y1
Fraternale, D; Gorassini, A; Verardo, G1
Chen, F; Li, W; Liu, DL; Lv, XM; Shao, LD; Wang, W; Wang, WJ1
Andre, CM; Berni, R; Cai, G; Guerriero, G; Hausman, JF; Hoque, MZ; Legay, S; Siddiqui, KS1
Bilia, AR; Hadjipavlou-Litina, D; Karioti, A; Stefanis, I1
Bruno, M; Fontana, G; Labbozzetta, M; Notarbartolo, M; Poma, P; Rosselli, S; Spinella, A1
Anh, NTN; Kiem, PV; Lam, DT; Le, VTT; Minh, PTH; Quan, PM; Tai, BH; Thuy, TTT1
Fujisawa, Y; Fukushima, EO; Ishimoto, M; Muranaka, T; Osakabe, K; Osakabe, Y; Seki, H; Shimizu, Y; Suzuki, H1
Ferreira, SS; Nunes, FM; Silva, AM; Silva, P1
Baltierra-Uribe, SL; Campillo-Navarro, M; Castillo-Cruz, J; Castrejón-Jiménez, NS; Chacón-Salinas, R; Coral-Vázquez, RM; Estrada-García, I; García-Pérez, BE; Hernández-Pérez, AD; Leyva-Paredes, K; Luna-Angulo, AB; Sánchez-Torres, LE; Torres-Torres, C1
Gubaidullin, RR; Khalitova, RR; Nedopekina, DA; Spivak, AY1
Bighelli, A; Casanova, J; Palu, D; Paoli, M1
Guan, Q; Guo, Y; Li, Y; Lv, S; Shang, E; Shi, L; Sun, S; Xiao, H; Yu, X; Zhao, C1
Wang, CS; Wei, MC; Yang, YC1
Bollag, R; Hasanali, SL; Jordan, AR; Kallifatidis, G; Klaassen, Z; Lokeshwar, BL; Lokeshwar, VB; Morera, DS; Smith, DK; Terris, MK; Wang, J1
Feng, B; Li, J; Tian, T; Yu, J; Zhang, X; Zhang, Y; Zhao, C; Zhao, L1
Chen, F; Leng, Y; Liu, D; Liu, X; Ren, Y; Shi, Y; Zhang, J1
Arandarcikaite, O; Bendokas, V; Gudoityte, E; Liobikas, J; Mazeikiene, I1
Hu, X; Liu, F; Liu, J; Wu, L; Xia, C; Xiong, Y; Yao, N; Yuan, L; Zhang, H; Zhang, L1
Le, XT; Matsumoto, K; Nguyen, HT; Nguyen, KM; Pham, HTN; Phung, HN; Van Nguyen, T1
Ai, Q; Chen, C; Shi, A; Wang, L; Wang, N; Wei, Y1
Baba, R; Iwata, S; Kitamura, N; Morimoto, H; Nakanishi, T; Osada, Y; Sennari, Y; Shen, M; Tanaka, Y; Todoroki, Y; Tsukada, J; Ueno, M; Wang, D; Yonezawa, T; Yoshida, Y; Zeng, Z1
Chen, L; Liu, M; Meng, X; Ming, T; Ren, S; Sun, Q; Tang, S; Tao, Q; Xu, H; Yang, H; Zeng, S; Zhao, H1
Al-Gareeb, AI; Al-Kuraishy, HM; Alexiou, A; Batiha, GE; Negm, WA1
Choi, JH; Choi, S; Choi, YJ; Chung, HY; Hyun, MK; Kim, DH; Lee, JY; Noh, SG; Park, CH; Park, D1
Galanty, A; Grabowska, K; Malarz, J; Podolak, I; Sołtys, A; Zagrodzki, P1
An, N; Cai, S; Pei, J; Peng, J; Wang, D; Wang, W; Wu, M; Zhan, X1
An, HM; Chen, JF; Ding, MR; Gu, C; Hu, B; Qu, YJ; Zhang, LM; Zhen, RR1
He, RJ; Huang, GB; Huang, RZ; Jiang, H; Liang, GB; Lin, CY; Ma, XL; Wei, JH; Zhang, Y1
Li, H; Lin, J; Liu, H; Liu, X; Mao, Q; Min, J; Wu, M; Zeng, R; Zhang, C; Zheng, A1
Paduch, R; Piet, M1
Qasaymeh, RM; Rotondo, D; Seidel, V1
Hao, CF; Kong, M; Li, SL; Lin, XY; Mao, Q; Xu, JD; Zhou, J; Zhou, SS; Zhu, H1
Debnath, SK; Dighe, V; Maske, P; Saini, V; Srivastava, R1
Gidwani, B; Jain, V; Joshi, V; Namdeo, P; Pandey, RK; Shukla, SS; Tiwari, S; Vyas, A1
Mao, J; Wang, X; Yang, B; Zhou, S; Zhu, Q1
Du, G; Jin, K; Li, J; Liu, J; Liu, L; Liu, Y; Lv, X; Shi, X; Yu, W1
Jeon, M; Jung, SY; Kang, WC; Kim, DY; Kim, JY; Kong, CH; Lee, WH; Min, JW; Park, K; Ryu, JH1
Li, SL; Long, F; Shen, H; Sun, Z; Wu, CY; Zeng, Z; Zhou, J1

Reviews

23 review(s) available for oleanolic acid and ursolic acid

ArticleYear
Bioactive triterpenoids from Salvia species.
    Journal of natural products, 2006, Volume: 69, Issue:3

    Topics: Plants, Medicinal; Salvia; Triterpenes

2006
Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies.
    European journal of medicinal chemistry, 2017, Mar-31, Volume: 129

    Topics: Anthelmintics; Humans; Medicine, Traditional; Phytotherapy; Plants, Medicinal

2017
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Biomedical Research; Cell Proliferation; Drug Design; Humans; Neoplasms; Triterpenes; Viruses

2019
Recent advances in the targeting of human DNA ligase I as a potential new strategy for cancer treatment.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Antineoplastic Agents; Cell Proliferation; DNA Ligase ATP; Enzyme Inhibitors; Humans; Neoplasms; Structure-Activity Relationship

2019
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Animals; Antiprotozoal Agents; Drug Discovery; Female; Humans; Pregnancy; Toxoplasma; Toxoplasmosis

2019
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Alkaloids; Animals; Biosynthetic Pathways; Drug Discovery; Drugs, Chinese Herbal; Humans; Oxindoles; Uncaria

2021
Pharmacology of oleanolic acid and ursolic acid.
    Journal of ethnopharmacology, 1995, Dec-01, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Humans; Hyperlipidemias; Inflammation; Liver; Oleanolic Acid; Triterpenes; Ursolic Acid

1995
Synthesis and anti-ulcer activity of new derivatives of glycyrrhetic, oleanolic and ursolic acids.
    Farmaco (Societa chimica italiana : 1989), 1998, Volume: 53, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Glycyrrhetinic Acid; Mice; Oleanolic Acid; Rats; Triterpenes; Ursolic Acid

1998
A review of natural and modified betulinic, ursolic and echinocystic acid derivatives as potential antitumor and anti-HIV agents.
    Mini reviews in medicinal chemistry, 2003, Volume: 3, Issue:6

    Topics: Anti-HIV Agents; Antineoplastic Agents; Betulinic Acid; HIV-1; HT29 Cells; Humans; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2003
Oleanolic acid and ursolic acid: research perspectives.
    Journal of ethnopharmacology, 2005, Aug-22, Volume: 100, Issue:1-2

    Topics: Animals; Humans; Medicine, Traditional; Oleanolic Acid; Plants, Medicinal; Triterpenes; Ursolic Acid

2005
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.
    Frontiers in bioscience (Landmark edition), 2011, 01-01, Volume: 16, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemoprevention; Glycosides; Humans; Mice; Oleanolic Acid; Triterpenes; Ursolic Acid

2011
Pomegranate and type 2 diabetes.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:5

    Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Ellagic Acid; Flowers; Fruit; Humans; Hydrolyzable Tannins; Hypoglycemic Agents; Lipid Peroxidation; Lythraceae; Middle East; NF-kappa B; Oleanolic Acid; Plant Extracts; Polyphenols; PPAR gamma; Seeds; Triterpenes; Ursolic Acid

2013
The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:8

    Topics: Animals; Diabetes Complications; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hypoglycemic Agents; Models, Biological; Oleanolic Acid; Oxidative Stress; Triterpenes; Ursolic Acid

2014
Review on anti-tumor effect of triterpene acid compounds.
    Journal of cancer research and therapeutics, 2014, Volume: 10 Suppl 1

    Topics: Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Humans; Neoplasms; Oleanolic Acid; Triterpenes; Ursolic Acid

2014
Ursolic Acid and Oleanolic Acid: Pentacyclic Terpenoids with Promising Anti-Inflammatory Activities.
    Recent patents on inflammation & allergy drug discovery, 2016, Volume: 10, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Drug Discovery; Humans; Inflammation; Inflammation Mediators; Molecular Targeted Therapy; Oleanolic Acid; Patents as Topic; Signal Transduction; Triterpenes; Ursolic Acid

2016
Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:23

    Topics: Animals; Antineoplastic Agents; Betulinic Acid; Biological Availability; Drug Delivery Systems; Drug Liberation; Humans; Nanocapsules; Neoplasms; Oleanolic Acid; Pentacyclic Triterpenes; Solubility; Triterpenes; Unilamellar Liposomes; Ursolic Acid; Water

2016
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018
Research Advances in Protective Effects of Ursolic Acid and Oleanolic Acid Against Gastrointestinal Diseases.
    The American journal of Chinese medicine, 2021, Volume: 49, Issue:2

    Topics: Gastrointestinal Diseases; Humans; Molecular Structure; Oleanolic Acid; Protective Agents; Triterpenes; Ursolic Acid

2021
Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential.
    International journal of molecular sciences, 2021, Apr-27, Volume: 22, Issue:9

    Topics: Animals; Drug Development; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2021
Oleanolic acid and ursolic acid: therapeutic potential in neurodegenerative diseases, neuropsychiatric diseases and other brain disorders.
    Nutritional neuroscience, 2023, Volume: 26, Issue:5

    Topics: Brain Diseases; Humans; Neurodegenerative Diseases; Oleanolic Acid; Quality of Life; Triterpenes; Ursolic Acid

2023
Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective.
    Inflammopharmacology, 2022, Volume: 30, Issue:5

    Topics: Acute Lung Injury; Anti-Inflammatory Agents; Antioxidants; Antiviral Agents; COVID-19 Drug Treatment; Cytokines; Humans; Inflammation; Oleanolic Acid; Reactive Oxygen Species; Respiratory Distress Syndrome; SARS-CoV-2; Ursolic Acid

2022
Therapeutic potential and novel formulations of ursolic acid and its derivatives: an updated review.
    Journal of the science of food and agriculture, 2023, Volume: 103, Issue:9

    Topics: Animals; Drug Compounding; Neoplasms; Oleanolic Acid; Solubility; Triterpenes; Ursolic Acid

2023

Other Studies

363 other study(ies) available for oleanolic acid and ursolic acid

ArticleYear
Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.
    Journal of natural products, 1998, Volume: 61, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Humans; Oleanolic Acid; Plants, Medicinal; Triterpenes; Viral Plaque Assay

1998
Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.
    Journal of natural products, 1998, Volume: 61, Issue:10

    Topics: Animals; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; In Vitro Techniques; Isoenzymes; Plantago; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep; Triterpenes; Ursolic Acid

1998
DNA polymerase beta inhibitors from Baeckea gunniana.
    Journal of natural products, 1999, Volume: 62, Issue:12

    Topics: Animals; Cattle; DNA Polymerase beta; Enzyme Inhibitors; Leukemia P388; Models, Chemical; Oleanolic Acid; Plant Extracts; Plant Leaves; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

1999
Anti-AIDS agents 38. Anti-HIV activity of 3-O-acyl ursolic acid derivatives.
    Journal of natural products, 2000, Volume: 63, Issue:12

    Topics: Anti-HIV Agents; Cell Line; HIV-1; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment; Triterpenes; Ursolic Acid

2000
Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Apoptosis; Betulinic Acid; Cell Differentiation; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Molecular Structure; Oxidation-Reduction; Pentacyclic Triterpenes; Pyridinium Compounds; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2002
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Antifeedant activity of some pentacyclic triterpene acids and their fatty acid ester analogues.
    Journal of agricultural and food chemistry, 2003, Mar-26, Volume: 51, Issue:7

    Topics: Animals; Diospyros; Eating; Insecticides; Oleanolic Acid; Plant Leaves; Spodoptera; Triterpenes; Ursolic Acid

2003
Synthesis of low molecular weight compounds with complement inhibition activity.
    Bioorganic & medicinal chemistry letters, 2003, Apr-07, Volume: 13, Issue:7

    Topics: Complement Inactivator Proteins; Complement Pathway, Classical; Dose-Response Relationship, Drug; Esters; Ethers; Hemolysis; Humans; In Vitro Techniques; Indicators and Reagents; Molecular Weight

2003
New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
    Journal of natural products, 2003, Volume: 66, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Guyana; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plant Stems; Plants, Medicinal; Rubiaceae; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2003
Sterol and triterpenoid constituents of Verbena littoralis with NGF-potentiating activity.
    Journal of natural products, 2003, Volume: 66, Issue:5

    Topics: Animals; Japan; Molecular Structure; Nerve Growth Factors; Neurites; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; PC12 Cells; Plants, Medicinal; Rats; Stereoisomerism; Stigmasterol; Triterpenes; Tumor Cells, Cultured; Ursolic Acid; Verbena

2003
Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.
    Journal of natural products, 2004, Volume: 67, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Flowers; Humans; Inhibitory Concentration 50; Madagascar; Malpighiaceae; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured

2004
Constituents of Senecio chionophilus with potential antitubercular activity.
    Journal of natural products, 2004, Volume: 67, Issue:9

    Topics: Antitubercular Agents; Chile; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Toxic; Senecio; Sesquiterpenes; Stereoisomerism

2004
Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.
    Journal of natural products, 2005, Volume: 68, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Screening Assays, Antitumor; Humans; Intercellular Adhesion Molecule-1; Japan; Models, Biological; Molecular Structure; Nerium; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured

2005
9,19-cyclolanostane derivatives from the roots of Actaea pachypoda.
    Journal of natural products, 2007, Volume: 70, Issue:1

    Topics: Actaea; Molecular Structure; Plant Roots; Plants, Medicinal; Triterpenes

2007
Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Antineoplastic Agents; Cytotoxins; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Styrenes; Tumor Cells, Cultured

2007
Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
    Journal of natural products, 2007, Volume: 70, Issue:8

    Topics: Animals; Benin; Cell Line, Tumor; Molecular Structure; Plant Leaves; Plants, Medicinal; Sterols; Stigmasterol; Structure-Activity Relationship; Strychnos; Triterpenes; Trypanocidal Agents; Trypanosoma brucei brucei

2007
Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:9

    Topics: Acetylation; Amides; Aromatase; Aromatase Inhibitors; Dose-Response Relationship, Drug; Esterification; Humans; Ilex paraguariensis; Inhibitory Concentration 50; Oxidation-Reduction; Triterpenes; Ursolic Acid

2008
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.
    Journal of medicinal chemistry, 2008, Sep-11, Volume: 51, Issue:17

    Topics: Animals; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Heterotrimeric GTP-Binding Proteins; Humans; Receptors, G-Protein-Coupled; Rhodopsin; Signal Transduction; Transducin

2008
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.
    Journal of natural products, 2008, Volume: 71, Issue:10

    Topics: Diospyros; Humans; Korea; Molecular Structure; Plant Leaves; Plants, Medicinal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Triterpenes

2008
Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.
    Journal of natural products, 2008, Volume: 71, Issue:10

    Topics: Animals; Antitubercular Agents; Biological Products; Chlorocebus aethiops; Inhibitory Concentration 50; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triterpenes; Ursolic Acid; Vero Cells

2008
Novel 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2)-curcumin, kojic acid, quercetin, and baicalein conjugates as HIV agents.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Antiviral Agents; Cell Line; Cell Survival; Curcumin; Flavanones; HIV Infections; HIV-1; Humans; Molecular Structure; Pyrones; Quercetin; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; T-Lymphocytes; Triterpenes; Viral Proteins

2009
Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.
    Journal of natural products, 2009, Volume: 72, Issue:8

    Topics: Animals; Drug Design; Glycogen Phosphorylase; Molecular Structure; Muscle, Skeletal; Oleanolic Acid; Pentacyclic Triterpenes; Rabbits; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2009
Palbinone and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant human HepG2 Cells.
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Topics: AMP-Activated Protein Kinases; Cell Line, Tumor; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Glucose; Glycogen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoglycemic Agents; Insulin Resistance; Paeonia; Phosphorylation; Terpenes; Triterpenes

2009
Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: 3T3-L1 Cells; Animals; Betulinic Acid; CHO Cells; Cricetinae; Cricetulus; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2010
Triterpenoid saponins from Symplocos lancifolia.
    Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Magnoliopsida; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Pseudomonas aeruginosa; Saponins; Staphylococcus aureus; Triterpenes; Vietnam

2011
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Enzyme Inhibitors; Glycogen Phosphorylase, Muscle Form; Models, Molecular; Molecular Conformation; Muscle, Skeletal; Pentacyclic Triterpenes; Quantitative Structure-Activity Relationship; Rabbits; Stereoisomerism

2011
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Male; Models, Molecular; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Wistar; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2011
Antituberculosis cycloartane triterpenoids from Radermachera boniana.
    Journal of natural products, 2011, May-27, Volume: 74, Issue:5

    Topics: Antitubercular Agents; Bignoniaceae; Molecular Structure; Mycobacterium tuberculosis; Plant Leaves; Triterpenes; Ursolic Acid

2011
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
    Journal of natural products, 2011, May-27, Volume: 74, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; HeLa Cells; HT29 Cells; Humans; Mitomycin; Models, Molecular; Molecular Structure; Mutation; Oleanolic Acid; Pentacyclic Triterpenes

2011
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
    Journal of natural products, 2012, Apr-27, Volume: 75, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Heme Oxygenase-1; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 1; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Triterpenes

2012
Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.
    Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

    Topics: Adenosine Triphosphate; Antiviral Agents; Apigenin; Breast; Cell Line; Cell Proliferation; Colorimetry; DNA; DNA Helicases; Epithelial Cells; Female; Flavonoids; Fluorescence Resonance Energy Transfer; Hepacivirus; Humans; Hydrolysis; Inhibitory Concentration 50; Kinetics; Methyltransferases; RNA Helicases; Severe acute respiratory syndrome-related coronavirus; Species Specificity; Viral Nonstructural Proteins; Viral Proteins

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytotoxins; HEK293 Cells; Hemolytic Agents; Hepacivirus; Humans; Oleanolic Acid; Rabbits; Structure-Activity Relationship; Virus Internalization

2013
Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Animals; Cell Line; Chalcones; Crystallography, X-Ray; Eucalyptus; Glucose Transporter Type 4; Models, Molecular; Molecular Structure; Plant Leaves; Rats; Xanthenes

2014
Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics.
    Journal of medicinal chemistry, 2014, Sep-11, Volume: 57, Issue:17

    Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cell Line, Tumor; Cell Survival; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Structure, Secondary; Sapogenins; Structure-Activity Relationship

2014
Synthesis and cytotoxic evaluation of novel ester-triazole-linked triterpenoid-AZT conjugates.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Araliaceae; Cytotoxins; Drug Evaluation, Preclinical; Eleutherococcus; Esters; Hep G2 Cells; Humans; Plant Extracts; Triazoles; Triterpenes; Zidovudine

2014
Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression.
    European journal of medicinal chemistry, 2015, May-05, Volume: 95

    Topics: Anti-Bacterial Agents; Gene Expression Regulation, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Pentacyclic Triterpenes; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Virulence

2015
Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2015
Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Female; Mice; Mice, Inbred Strains; Molecular Conformation; Oleanolic Acid; Oxygen; Skin; Triterpenes; Ursolic Acid

2015
Design, synthesis, and biofunctional evaluation of novel pentacyclic triterpenes bearing O-[4-(1-piperazinyl)-4-oxo-butyryl moiety as antiproliferative agents.
    Bioorganic & medicinal chemistry letters, 2015, Oct-15, Volume: 25, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pentacyclic Triterpenes; Piperazines; Structure-Activity Relationship

2015
Chemical constituents from Hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Agaricales; Animals; Ceramides; Ergosterol; Fruiting Bodies, Fungal; Monoterpenes; Nerve Growth Factors; Neurites; PC12 Cells; Phytosterols; Rats; Stereoisomerism; Triterpenes

2015
Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Binding, Competitive; Drug Discovery; Humans; Isocitrate Dehydrogenase; MCF-7 Cells; Molecular Structure; Mutation; Recombinant Proteins; Structure-Activity Relationship; Xanthones

2015
Targeting cancer cells with oleanolic and ursolic acid derived hydroxamates.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2016
Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis.
    Bioorganic & medicinal chemistry letters, 2016, May-01, Volume: 26, Issue:9

    Topics: Drug Evaluation, Preclinical; Plant Extracts; Plants, Medicinal; Trichomonas vaginalis

2016
Urea derivates of ursolic, oleanolic and maslinic acid induce apoptosis and are selective cytotoxic for several human tumor cell lines.
    European journal of medicinal chemistry, 2016, Aug-25, Volume: 119

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mice; NIH 3T3 Cells; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2016
Discovery of ursolic acid prodrug (NX-201): Pharmacokinetics and in vivo antitumor effects in PANC-1 pancreatic cancer.
    Bioorganic & medicinal chemistry letters, 2016, 11-15, Volume: 26, Issue:22

    Topics: Animals; Cell Line, Tumor; Humans; Mice, SCID; Pancreas; Pancreatic Neoplasms; Prodrugs; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays

2016
Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Animals; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Interleukin-6; Macrophages; MCF-7 Cells; Mice; Molecular Structure; Myrtaceae; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Triterpenes; Tumor Necrosis Factor-alpha

2016
Rhodamine B conjugates of triterpenoic acids are cytotoxic mitocans even at nanomolar concentrations.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Animals; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mitochondria; NIH 3T3 Cells; Rhodamines; Structure-Activity Relationship; Triterpenes

2017
Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Amides; Anti-HIV Agents; Binding Sites; Caffeic Acids; Coumaric Acids; DNA-Directed DNA Polymerase; Esters; HIV Reverse Transcriptase; Plant Extracts; Ribonuclease H, Human Immunodeficiency Virus; Structure-Activity Relationship; Triterpenes

2017
Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dammaranes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Plant Leaves; Triterpenes; Viburnum

2017
Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Animals; Cholesterol Ester Transfer Proteins; Dose-Response Relationship, Drug; Drug Discovery; Esters; Guinea Pigs; Humans; Mice; Mice, Transgenic; Molecular Structure; Structure-Activity Relationship; Triterpenes

2017
Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose.
    Bioorganic & medicinal chemistry letters, 2017, 11-15, Volume: 27, Issue:22

    Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Drug Synergism; Inhibitory Concentration 50; Kinetics; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes

2017
Synthesis and antimycobacterial activity of triterpeni≿ A-ring azepanes.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Antitubercular Agents; Azepines; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triterpenes

2018
Design, synthesis and biological evaluation of seco-A-pentacyclic triterpenoids-3,4-lactone as potent non-nucleoside HBV inhibitors.
    Bioorganic & medicinal chemistry letters, 2018, 05-15, Volume: 28, Issue:9

    Topics: Antiviral Agents; DNA Replication; Dose-Response Relationship, Drug; Drug Design; Hepatitis B Surface Antigens; Hepatitis B virus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triterpenes

2018
Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives.
    Bioorganic & medicinal chemistry, 2018, 08-15, Volume: 26, Issue:15

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Molecular Conformation; NF-kappa B; Plant Extracts; Plant Leaves; Structure-Activity Relationship; Syzygium; Triterpenes; Ursolic Acid

2018
Sentulic acid isolated from Sandoricum koetjape Merr attenuates lipopolysaccharide and interferon gamma co-stimulated nitric oxide production in murine macrophage RAW264 cells.
    Bioorganic & medicinal chemistry letters, 2018, 12-01, Volume: 28, Issue:22

    Topics: Animals; Cyclooxygenase 2; Down-Regulation; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Macrophages; Meliaceae; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptors; Triterpenes; Tumor Necrosis Factor-alpha

2018
Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.
    Journal of natural products, 2018, 10-26, Volume: 81, Issue:10

    Topics: Enzyme Inhibitors; HEK293 Cells; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; NF-kappa B; Triterpenes

2018
Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.
    Journal of medicinal chemistry, 2018, 12-13, Volume: 61, Issue:23

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Caspases; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chemistry Techniques, Synthetic; Drug Design; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Neoplastic Stem Cells; Reactive Oxygen Species; Triterpenes

2018
Synthesis and antitumor activity of fluorouracil - oleanolic acid/ursolic acid/glycyrrhetinic acid conjugates.
    MedChemComm, 2019, Aug-01, Volume: 10, Issue:8

    Topics:

2019
Design, synthesis and cytotoxicity of BODIPY FL labelled triterpenoids.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Antineoplastic Agents; Boron Compounds; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Triterpenes

2020
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
Optimized plant compound with potent anti-biofilm activity across gram-negative species.
    Bioorganic & medicinal chemistry, 2020, 03-01, Volume: 28, Issue:5

    Topics: Amines; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2020
Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 human pancreatic cancer cell line.
    Bioorganic & medicinal chemistry letters, 2020, 08-15, Volume: 30, Issue:16

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Egypt; Humans; Molecular Structure; Myrtaceae; Pancreatic Neoplasms; Structure-Activity Relationship; Terpenes; Tumor Microenvironment

2020
Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of
    Journal of natural products, 2020, 10-23, Volume: 83, Issue:10

    Topics: Carboxylesterase; Cell Line, Tumor; Enzyme Inhibitors; Glucosides; Humans; Molecular Structure; Monoterpenes; Paeonia; Plant Extracts; Plant Roots; Sesquiterpenes; Structure-Activity Relationship

2020
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides.
    Journal of natural products, 2020, 11-25, Volume: 83, Issue:11

    Topics: Amides; Drug Discovery; HEK293 Cells; Humans; Molecular Docking Simulation; Triterpenes; TRPV Cation Channels

2020
Antibacterial and antitumoral properties of 1,2,3-triazolo fused triterpenes and their mechanism of inhibiting the proliferation of HL-60 cells.
    European journal of medicinal chemistry, 2021, Nov-15, Volume: 224

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Proliferation; HL-60 Cells; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triterpenes

2021
Dual High-Resolution α-Glucosidase and PTP1B Inhibition Profiling Combined with HPLC-PDA-HRMS-SPE-NMR Analysis for the Identification of Potentially Antidiabetic Chromene Meroterpenoids from
    Journal of natural products, 2021, 09-24, Volume: 84, Issue:9

    Topics: alpha-Glucosidases; China; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Molecular Structure; Phytochemicals; Plant Components, Aerial; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rhododendron; Terpenes

2021
[Chemical constituents of Vaccinium scopulorum W.W. Smith].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:4

    Topics: Drugs, Chinese Herbal; Oleanolic Acid; Triterpenes; Ursolic Acid

1992
Intervention of adriamycin induced free radical damage.
    Biochemistry international, 1992, Volume: 28, Issue:4

    Topics: Animals; Calcium; Cell Fractionation; Centrifugation; Doxorubicin; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Male; Microsomes; Microsomes, Liver; Myocardium; Oleanolic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Triterpenes; Ursolic Acid

1992
[Chemical constituents of Actinidia arguta (Sieb. et Zucc.) Planch. ex Miquel].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:1

    Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Oleanolic Acid; Sitosterols; Succinates; Succinic Acid; Triterpenes; Ursolic Acid

1992
Protective effect of oleanolic acid and ursolic acid against lipid peroxidation.
    Biochemistry international, 1991, Volume: 24, Issue:5

    Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Carbon Tetrachloride; Iron; Lipid Peroxidation; Microsomes, Liver; Oleanolic Acid; Rats; Triterpenes; Ursolic Acid

1991
Inhibition of glucosyltransferase from Streptococcus mutans by oleanolic acid and ursolic acid.
    Caries research, 1987, Volume: 21, Issue:2

    Topics: Anti-Bacterial Agents; Glucans; Glucosyltransferases; Oleanolic Acid; Sapogenins; Streptococcus mutans; Sucrose; Triterpenes; Ursolic Acid

1987
Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation; ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant, Glechoma hederaceae L.
    Cancer letters, 1986, Volume: 30, Issue:2

    Topics: Biological Assay; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Lyngbya Toxins; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Oleanolic Acid; Phorbols; Plants, Medicinal; Sapogenins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid; Virus Activation; Virus Cultivation

1986
Inhibitory effects of ursolic and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer letters, 1986, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Female; Mice; Mice, Inbred ICR; Oleanolic Acid; Sapogenins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Triterpenes; Ursolic Acid

1986
Anti-angiogenic activity of triterpene acids.
    Cancer letters, 1995, Aug-01, Volume: 94, Issue:2

    Topics: Allantois; Animals; Chick Embryo; Chorion; Dose-Response Relationship, Drug; Neovascularization, Pathologic; Oleanolic Acid; Triterpenes; Ursolic Acid

1995
Isolation of substances from glossy privet (Ligustrum lucidum Ait.) inhibiting the mutagenicity of benzo[a]pyrene in bacteria.
    Mutation research, 1993, Volume: 319, Issue:1

    Topics: Antimutagenic Agents; Benzo(a)pyrene; Glucosides; Mutagenicity Tests; Oleanolic Acid; Plant Extracts; Pyrans; Salmonella typhimurium; Sugar Alcohols; Trees; Triterpenes; Ursolic Acid

1993
[Qualitative analysis of Chinese drug xiakucao (Prunella)].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1993, Volume: 18, Issue:11

    Topics: Chromatography, Gas; Drugs, Chinese Herbal; Oleanolic Acid; Quality Control; Seasons; Triterpenes; Ursolic Acid

1993
Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids.
    Journal of cancer research and clinical oncology, 1994, Volume: 120, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Blotting, Northern; Cell Differentiation; Mice; Molecular Sequence Data; Nuclear Proteins; Oleanolic Acid; Receptors, Glucocorticoid; Regulatory Sequences, Nucleic Acid; Teratocarcinoma; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

1994
Phytochemical studies of seeds of medicinal plants. III. Ursolic acid and oleanolic acid glycosides from seeds of Patrinia scabiosaefolia Fischer.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:1

    Topics: Carbohydrate Sequence; Glycosides; Medicine, Chinese Traditional; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Triterpenes; Ursolic Acid

1993
Natural-product inhibitors of human DNA ligase I.
    The Biochemical journal, 1996, Mar-15, Volume: 314 ( Pt 3)

    Topics: Adenosine Triphosphate; Alkaloids; DNA Ligase ATP; DNA Ligases; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Oleanolic Acid; Oligodeoxyribonucleotides; Plant Extracts; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Triterpenes; Ursolic Acid

1996
Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice.
    Cancer letters, 1997, Jan-01, Volume: 111, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Combined Modality Therapy; Drug Screening Assays, Antitumor; Leukocyte Count; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Sarcoma 180; Triterpenes; Ursolic Acid

1997
Oleanolic acid and ursolic acid stabilize liposomal membranes.
    Lipids, 1997, Volume: 32, Issue:7

    Topics: Diphenylhexatriene; Fluoresceins; Fluorescence Polarization; Hot Temperature; Liposomes; Membrane Fluidity; Oleanolic Acid; Permeability; Triterpenes; Ursolic Acid

1997
Effect of selected triterpenoids on chronic dermal inflammation.
    European journal of pharmacology, 1997, Sep-03, Volume: 334, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Dermatitis, Contact; Dexamethasone; Drug Evaluation, Preclinical; Female; Mice; Oleanolic Acid; Pentacyclic Triterpenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid

1997
Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages.
    Cancer research, 1998, Feb-15, Volume: 58, Issue:4

    Topics: Animals; Cell Line; Enzyme Inhibitors; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleanolic Acid; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Triterpenes; Ursolic Acid

1998
Induction of differentiation of the cultured rat mammary epithelial cells by triterpene acids.
    Archives of pharmacal research, 1998, Volume: 21, Issue:4

    Topics: Animals; Apoptosis; Cell Communication; Cell Cycle; Cell Differentiation; Cell Division; Cells, Cultured; Collagen; Culture Techniques; Drug Combinations; Epithelial Cells; Female; Immunohistochemistry; Isoantibodies; Laminin; Mammary Glands, Animal; Oleanolic Acid; Organoids; Peanut Agglutinin; Proteoglycans; Rats; Rats, Inbred F344; Triterpenes; Ursolic Acid

1998
In vitro and in vivo evaluation of betulinic acid as an antimalarial.
    Phytotherapy research : PTR, 1999, Volume: 13, Issue:2

    Topics: Animals; Antimalarials; Betulinic Acid; Disease Models, Animal; Euphorbiaceae; Malaria; Mice; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plant Roots; Plasmodium berghei; Plasmodium falciparum; Random Allocation; Structure-Activity Relationship; Triterpenes; Ursolic Acid

1999
Quantitative determination of hydroxy pentacyclic triterpene acids in vegetable oils.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:4

    Topics: Chromatography, Gas; Oleanolic Acid; Olive Oil; Plant Oils; Reproducibility of Results; Species Specificity; Triterpenes; Ursolic Acid

1999
Cytotoxic triterpene acids from the Peruvian medicinal plant Polylepis racemosa.
    Planta medica, 2000, Volume: 66, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Humans; Magnetic Resonance Spectroscopy; Mice; Oleanolic Acid; Peru; Plant Stems; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2000
Cytotoxic triterpenes from stem bark of Physocarpus intermedius.
    Planta medica, 2000, Volume: 66, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Humans; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pentacyclic Triterpenes; Plant Stems; Rosales; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2000
[Chemical studies on Campylotropis hirtella (Franch. Schindl.)].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:11

    Topics: Drugs, Chinese Herbal; Fabaceae; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sitosterols; Triterpenes; Ursolic Acid

1997
Eclalbatin, a triterpene saponin from Eclipta alba.
    Journal of Asian natural products research, 2001, Volume: 3, Issue:3

    Topics: Asteraceae; Chromatography, Thin Layer; India; Mass Spectrometry; Medicine, Traditional; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Saponins; Spectrophotometry, Infrared; Triterpenes; Ursolic Acid

2001
Topical anti-inflammatory activity of Thymus willdenowii.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:12

    Topics: Administration, Topical; Anti-Inflammatory Agents; Flavonoids; Lamiaceae; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2001
Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15.
    World journal of gastroenterology, 2002, Volume: 8, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Humans; Oleanolic Acid; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2002
Partial synthesis of 23-hydroxyursolic acid isolated from medicinal plants of the Rubiaceae family.
    Natural product letters, 2002, Volume: 16, Issue:4

    Topics: Infrared Rays; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plants, Medicinal; Rubiaceae; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Triterpenes; Ursolic Acid

2002
Topical anti-inflammatory activity of extracts and compounds from Thymus broussonettii.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:8

    Topics: Administration, Topical; Animals; Biological Assay; Croton Oil; Dermatologic Agents; Flavonoids; Glycosides; Inflammation; Lamiaceae; Male; Mice; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2002
[Determination of oleanolic acid and ursolic acid in spica Prunellae by derivative GC method].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1999, Volume: 24, Issue:12

    Topics: Chromatography, Gas; Oleanolic Acid; Plants, Medicinal; Prunella; Triterpenes; Ursolic Acid

1999
Alysinol--a new triterpene from Alysicarpus monolifer.
    Natural product letters, 2002, Volume: 16, Issue:6

    Topics: Acetylation; Benzoates; Hydroxybenzoates; Methanol; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pakistan; Plant Extracts; Plants, Medicinal; Triterpenes; Ursolic Acid

2002
Biosynthesis of sterols and triterpenes in cell suspension cultures of Uncaria tomentosa.
    Plant & cell physiology, 2002, Volume: 43, Issue:12

    Topics: Carbon-Carbon Double Bond Isomerases; Cat's Claw; Cells, Cultured; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Hemiterpenes; Mevalonic Acid; Naphthalenes; Oleanolic Acid; Oxygenases; Pectins; Phosphoric Monoester Hydrolases; Phytosterols; Sitosterols; Squalene; Squalene Monooxygenase; Terbinafine; Triterpenes; Tritium; Ursolic Acid

2002
[Studies on chemical constituents in the roots of Rabdosia japonica (Burm.f). Hara var. glaucocalyx (Maxin) Hara].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:11

    Topics: Diterpenes, Kaurane; Drugs, Chinese Herbal; Isodon; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sitosterols; Triterpenes; Ursolic Acid

2000
[The research on the chemical components of Schizonepeta tenuifolia Briq].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2001, Volume: 24, Issue:3

    Topics: Eicosanoic Acids; Lamiaceae; Oleanolic Acid; Sitosterols; Triterpenes; Ursolic Acid

2001
[Studies on the triterpenoidal saponins from flowers of Eriobotrya japonica].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2001, Volume: 32, Issue:2

    Topics: Eriobotrya; Gas Chromatography-Mass Spectrometry; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Saponins; Triterpenes; Ursolic Acid

2001
Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves.
    Journal of ethnopharmacology, 2003, Volume: 84, Issue:2-3

    Topics: Animals; Antihypertensive Agents; Antioxidants; Artemia; Arteriosclerosis; Blood Glucose; Diuretics; Greece; Hemodynamics; Lipids; Magnetic Resonance Spectroscopy; Olea; Oleanolic Acid; Plant Extracts; Plant Leaves; Rats; Rats, Inbred Dahl; South Africa; Triterpenes; Ursolic Acid

2003
Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, Volume: 10, Issue:2-3

    Topics: Animals; Antioxidants; Artemia; Blood Pressure; Cardiovascular Agents; Heart Rate; Hypolipidemic Agents; Male; Models, Animal; Oleanolic Acid; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Syzygium; Triterpenes; Ursolic Acid

2003
[HPLC determination of oleanolic acid and llrolic acid in Chinese medicinal herbs].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:9

    Topics: Chromatography, High Pressure Liquid; Hedyotis; Ligustrum; Lycopus; Oleanolic Acid; Plants, Medicinal; Triterpenes; Ursolic Acid

2001
In vitro TGF-beta1 antagonistic activity of ursolic and oleanolic acids isolated from Clerodendranthus spicatus.
    Planta medica, 2003, Volume: 69, Issue:7

    Topics: 3T3 Cells; Animals; China; Drugs, Chinese Herbal; Lamiaceae; Mice; Mice, Inbred BALB C; Oleanolic Acid; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid

2003
[Chemical constituents in the roots of Salvia przewalskii Maxim].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:5

    Topics: Heterocyclic Compounds, 4 or More Rings; Molecular Conformation; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Quinones; Salvia; Triterpenes; Ursolic Acid

2003
Oleanolic acid from cranberries.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1953, Volume: 42, Issue:10

    Topics: Humans; Oleanolic Acid; Terpenes; Triterpenes; Ursolic Acid; Vaccinium macrocarpon

1953
Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, Volume: 10, Issue:6-7

    Topics: Animals; Benzoxepins; Bone Marrow Cells; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Hypersensitivity, Delayed; Immune System; Injections, Intraperitoneal; Leukocyte Count; Limonins; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; Phytotherapy; Sheep; Spleen; Triterpenes; Ursolic Acid

2003
[On the quantitative determination of ursolic acid and oleanolic acid by means of the Liebermann-Burchard reaction].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1962, Volume: 295/67

    Topics: Oleanolic Acid; Terpenes; Triterpenes; Ursolic Acid

1962
MECC determination of oleanolic acid and ursolic acid isomers in Ligustrum lucidum Ait.
    Journal of pharmaceutical and biomedical analysis, 2003, Jul-14, Volume: 32, Issue:3

    Topics: Algorithms; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Indicators and Reagents; Ligustrum; Oleanolic Acid; Plant Extracts; Quality Control; Reproducibility of Results; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid

2003
Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Artemia; Calcium Chloride; Cardiotonic Agents; Dose-Response Relationship, Drug; Epinephrine; Male; Olea; Oleanolic Acid; Phytotherapy; Plant Leaves; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2004
Rapid analysis of triterpenic acids by liquid chromatography using porous graphitic carbon and evaporative light scattering detection.
    Journal of separation science, 2004, Volume: 27, Issue:12

    Topics: Betulinic Acid; Carbon; Chromatography, Liquid; Glycyrrhetinic Acid; Light; Models, Chemical; Models, Molecular; Oleanolic Acid; Pentacyclic Triterpenes; Scattering, Radiation; Time Factors; Triterpenes; Ultraviolet Rays; Ursolic Acid

2004
Antimicrobial activity of some pentacyclic triterpenes and their synthesized 3-O-lipophilic chains.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:10

    Topics: Anti-Bacterial Agents; Bacteria; Diospyros; Esterification; Fatty Acids; Microbial Sensitivity Tests; Molecular Weight; Oleanolic Acid; Plant Extracts; Plant Leaves; Triterpenes; Ursolic Acid

2004
Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Erythroblasts; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Triterpenes; Ursolic Acid; Viscum

2005
Determination of oleanolic acid and ursolic acid in cornel by cyclodextrin-modified micellar electrokinetic chromatography.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:7

    Topics: beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Cornus; Fruit; Oleanolic Acid; Sensitivity and Specificity; Triterpenes; Ursolic Acid

2005
[Changes in level of organic acids in fructus crataegi after processing].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:11

    Topics: Citric Acid; Crataegus; Drugs, Chinese Herbal; Fruit; Hot Temperature; Malates; Oleanolic Acid; Plants, Medicinal; Technology, Pharmaceutical; Triterpenes; Ursolic Acid

2004
[Studies on chemical constituents in fruit of Rubus chingii].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:3

    Topics: Fruit; Oleanolic Acid; Plants, Medicinal; Rosaceae; Triterpenes; Ursolic Acid

2005
DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside.
    Natural product research, 2005, Volume: 19, Issue:5

    Topics: Ajuga; DNA Damage; Iridoids; Oleanolic Acid; Plant Extracts; Sitosterols; Sterols; Triterpenes; Ursolic Acid

2005
Induced accumulation of oleanolic acid and ursolic acid in cell suspension cultures of Uncaria tomentosa.
    Biotechnology letters, 2005, Volume: 27, Issue:12

    Topics: Biomass; Cat's Claw; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Molecular Structure; Oleanolic Acid; Sucrose; Time Factors; Triterpenes; Ursolic Acid

2005
[Studies on the triterpenoids of Cyclocarya paliurus (Batal.) Iljinsk].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:7

    Topics: Juglandaceae; Magnetic Resonance Spectroscopy; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Powders; Triterpenes; Ursolic Acid

2005
Phytocomponents of triterpenoids, oleanolic acid and ursolic acid, regulated differently the processing of epidermal keratinocytes via PPAR-alpha pathway.
    Experimental dermatology, 2006, Volume: 15, Issue:1

    Topics: Animals; Cell Differentiation; Cell Line; Cell Line, Transformed; Ceramides; Epidermis; Humans; Keratinocytes; Mice; Oleanolic Acid; Permeability; Plants; PPAR alpha; Triterpenes; Ursolic Acid

2006
Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:2

    Topics: Animals; Betulinic Acid; Cell Line; Enzyme Inhibitors; Humans; Lycopus; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Triterpenes; Ursolic Acid

2006
Dual activity of triterpenoids: apoptotic versus antidifferentiation effects.
    Archives of toxicology, 2006, Volume: 80, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Doxorubicin; Drug Combinations; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Leukemia L1210; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Oleanolic Acid; Triterpenes; Ursolic Acid

2006
[Triterpenes from root of Rhaponticum uniflorum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:23

    Topics: Leuzea; Oleanolic Acid; Plant Roots; Plants, Medicinal; Triterpenes; Ursolic Acid

2005
Antimutagenicity of ursolic acid and oleanolic acid against doxorubicin-induced clastogenesis in Balb/c mice.
    Life sciences, 2006, Aug-22, Volume: 79, Issue:13

    Topics: Animals; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Doxorubicin; Erythrocytes; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mutagens; Oleanolic Acid; Triterpenes; Ursolic Acid

2006
Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity.
    Planta medica, 2006, Volume: 72, Issue:9

    Topics: Androgen Antagonists; Animals; Cell Line; Cucurbita; Genes, Reporter; Haplorhini; Luciferases; Oleanolic Acid; Plant Extracts; Prunus africana; Serenoa; Sitosterols; Sulfonamides; Triterpenes; Ursolic Acid

2006
Protective effects of ursolic acid and oleanolic acid in leukemic cells.
    Mutation research, 2006, Aug-30, Volume: 600, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia; Mice; Oleanolic Acid; Triterpenes; Ursolic Acid

2006
Isomers (oleanolic and ursolic acids) differ in their protective effect against isoproterenol-induced myocardial ischemia in rats.
    International journal of cardiology, 2007, Jun-25, Volume: 119, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Isoproterenol; Male; Myocardial Ischemia; Oleanolic Acid; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2007
Trypanocidal activity of triterpenes from Arrabidaea triplinervia and derivatives.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:11

    Topics: Animals; Bignoniaceae; Chagas Disease; Dose-Response Relationship, Drug; Erythrocytes; Mass Spectrometry; Mice; Molecular Structure; Oleanolic Acid; Parasitic Sensitivity Tests; Phytotherapy; Plant Extracts; Plant Leaves; Structure-Activity Relationship; Triterpenes; Trypanocidal Agents; Trypanosoma cruzi; Ursolic Acid

2006
Determination of free isomeric oleanolic acid and ursolic acid in Pterocephalus hookeri by capillary zone electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2007, Mar-12, Volume: 43, Issue:4

    Topics: beta-Cyclodextrins; Drugs, Chinese Herbal; Electrophoresis, Capillary; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Stereoisomerism; Time Factors; Triterpenes; Ursolic Acid

2007
[Study on the chemical constituents of Sambucus chinensis Lindl].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:9

    Topics: Flavonols; Magnetic Resonance Imaging; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Sambucus; Sitosterols; Triterpenes; Ursolic Acid

2006
Carbenoxolone and triterpenoids inhibited mucin secretion from airway epithelial cells.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Animals; Carbenoxolone; Cells, Cultured; Cricetinae; Epithelial Cells; Mucins; Oleanolic Acid; Respiratory Mucosa; Triterpenes; Ursolic Acid

2007
Studies of selected plant raw materials as alternative sources of triterpenes of oleanolic and ursolic acid types.
    Journal of agricultural and food chemistry, 2007, Feb-07, Volume: 55, Issue:3

    Topics: Asteraceae; Calendula; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Oleanolic Acid; Panax; Plant Leaves; Plant Roots; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2007
Oxyfunctionalization products of terpenoids with dimethyldioxirane and their biological activity.
    Chemical & pharmaceutical bulletin, 2007, Volume: 55, Issue:2

    Topics: Acetates; alpha-Glucosidases; Diterpenes; Epoxy Compounds; Magnetic Resonance Spectroscopy; Oleanolic Acid; Oxidation-Reduction; Pentacyclic Triterpenes; Plants, Medicinal; Terpenes; Triterpenes; Ursolic Acid

2007
[Chemical constituents of the non-alkaloid fraction of Uncaria macrophylla].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:2

    Topics: Oleanolic Acid; Triterpenes; Uncaria; Ursolic Acid

2007
Determination of oleanolic acid, ursolic acid and amygdalin in the flower of Eriobotrya japonica Lindl. by HPLC.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:7

    Topics: Amygdalin; Chromatography, High Pressure Liquid; Eriobotrya; Flowers; Oleanolic Acid; Reproducibility of Results; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid

2007
Use of liquid chromatography-atmospheric pressure chemical ionization-ion trap mass spectrometry for identification of oleanolic acid and ursolic acid in Anoectochilus roxburghii (wall.) Lindl.
    Journal of mass spectrometry : JMS, 2007, Volume: 42, Issue:7

    Topics: Carbon Dioxide; Chromatography, Liquid; Chromatography, Supercritical Fluid; Mass Spectrometry; Oleanolic Acid; Plants; Reproducibility of Results; Solvents; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2007
Separation and determination of closely related triterpenic acids by high performance thin-layer chromatography after iodine derivatization.
    Journal of pharmaceutical and biomedical analysis, 2007, Oct-18, Volume: 45, Issue:2

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Iodine; Molecular Structure; Oleanolic Acid; Reproducibility of Results; Triterpenes; Ursolic Acid

2007
Inhibition of Escherichia coli heat-labile enterotoxin-induced diarrhea by Chaenomeles speciosa.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: 1-Butanol; Acetates; Animals; Antidiarrheals; Bacterial Toxins; Betulinic Acid; Diarrhea; Dose-Response Relationship, Drug; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Escherichia coli Proteins; Female; Fruit; Immunoglobulin M; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Protein Binding; Protein Subunits; Rosaceae; Triterpenes; Ursolic Acid

2007
Nonenzymatic antioxidative and antiglycative effects of oleanolic acid and ursolic acid.
    Journal of agricultural and food chemistry, 2007, Aug-22, Volume: 55, Issue:17

    Topics: alpha-Tocopherol; Antioxidants; Glycosylation; Hydrogen-Ion Concentration; Oleanolic Acid; Triterpenes; Ursolic Acid

2007
Antihistaminic and antieicosanoid effects of oleanolic and ursolic acid fraction from Helichrysum picardii.
    Die Pharmazie, 2007, Volume: 62, Issue:6

    Topics: Animals; Calcimycin; Chromatography, Thin Layer; Cytoplasmic Granules; Eicosanoids; Flowers; Gas Chromatography-Mass Spectrometry; Helichrysum; Histamine Antagonists; Histamine Release; In Vitro Techniques; Indicators and Reagents; Ionophores; Isomerism; Leukocytes; Male; Mast Cells; Methanol; Oleanolic Acid; p-Methoxy-N-methylphenethylamine; Peroxidase; Rats; Rats, Wistar; Solvents; Triterpenes; Ursolic Acid

2007
Simultaneous effect of ursolic acid and oleanolic acid on epidermal permeability barrier function and epidermal keratinocyte differentiation via peroxisome proliferator-activated receptor-alpha.
    The Journal of dermatology, 2007, Volume: 34, Issue:9

    Topics: Animals; Blotting, Western; Cell Differentiation; Cell Line; Epidermis; Filaggrin Proteins; Intermediate Filament Proteins; Keratinocytes; Membrane Proteins; Mice; Mice, Hairless; Microscopy, Electron; Oleanolic Acid; Permeability; PPAR alpha; Protein Precursors; Skin; Triterpenes; Ursolic Acid; Water Loss, Insensible

2007
[Studies on triterpenoid constituents in leaf of Ilex pernyi].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:18

    Topics: Ilex; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Triterpenes; Ursolic Acid

2007
21beta-Hydroxy-oleanane-type triterpenes from Hippocratea excelsa.
    Phytochemistry, 2008, Volume: 69, Issue:4

    Topics: Hippocrateaceae; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Triterpenes; Ursolic Acid

2008
[Separation and determination of oleanolic acid and ursolic acid from Cornus officinalis by capillary electrophoresis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2007, Volume: 30, Issue:8

    Topics: 2-Propanol; beta-Cyclodextrins; Cornus; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Reproducibility of Results; Sodium Dodecyl Sulfate; Triterpenes; Ursolic Acid

2007
Isolation of oleanolic acid and ursolic acid from Thymus vulgaris, L.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1949, Volume: 38, Issue:3 Pt. 1

    Topics: Humans; Oleanolic Acid; Thymus Plant; Triterpenes; Ursolic Acid

1949
Antimycobacterial activity of cinnamate-based esters of the triterpenes betulinic, oleanolic and ursolic acids.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:2

    Topics: Acetylation; Antitubercular Agents; Betulinic Acid; Cinnamates; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methylation; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oleanolic Acid; Pentacyclic Triterpenes; Spectrometry, Mass, Fast Atom Bombardment; Spectroscopy, Fourier Transform Infrared; Triterpenes; Ursolic Acid

2008
Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha.
    Chemistry & biodiversity, 2008, Volume: 5, Issue:2

    Topics: Aldehyde Reductase; Animals; Apigenin; Ellagic Acid; Glycation End Products, Advanced; Glycosides; Lens, Crystalline; Molecular Structure; Oleanolic Acid; Quercetin; Rats; Rats, Sprague-Dawley; Rosaceae; Stereoisomerism; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2008
Ursolic acid and oleanolic acid suppress preneoplastic lesions induced by 1,2-dimethylhydrazine in rat colon.
    Toxicologic pathology, 2008, Volume: 36, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Colonic Neoplasms; Male; Melastomataceae; Oleanolic Acid; Plant Components, Aerial; Precancerous Conditions; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2008
Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents.
    Journal of enzyme inhibition and medicinal chemistry, 2008, Volume: 23, Issue:5

    Topics: Animals; Antiprotozoal Agents; Humans; Inhibitory Concentration 50; Leishmania; Leishmania infantum; Leishmania mexicana; Monocytes; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2008
Efficient access to 2-isobetulinic acid, 2-isooleanolic acid, and 2-isoursolic acid.
    The Journal of organic chemistry, 2008, Sep-19, Volume: 73, Issue:18

    Topics: Betulinic Acid; Molecular Conformation; Oleanolic Acid; Pentacyclic Triterpenes; Stereoisomerism; Triterpenes; Ursolic Acid

2008
Antioxidative and anti-inflammatory protection of oleanolic acid and ursolic acid in PC12 cells.
    Journal of food science, 2008, Volume: 73, Issue:7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Cell Death; Glutathione Peroxidase; Hydrogen Peroxide; Interleukin-6; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Oleanolic Acid; Oxidative Stress; PC12 Cells; Rats; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2008
Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
    Journal of ethnopharmacology, 2008, Nov-20, Volume: 120, Issue:2

    Topics: Anti-Bacterial Agents; Betulinic Acid; Cell Line; Cell Survival; Drug Resistance, Bacterial; Eukaryotic Cells; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Toxicity Tests; Triterpenes; Ursolic Acid

2008
Solid-phase extraction of ursolic acid from herb using beta-cyclodextrin-based molecularly imprinted microspheres.
    Journal of separation science, 2008, Volume: 31, Issue:20

    Topics: Adsorption; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Ilex; Microspheres; Molecular Imprinting; Molecular Structure; Oleanolic Acid; Solid Phase Extraction; Triterpenes; Ursolic Acid

2008
Hsian-tsao (Mesona procumbens Heml.) prevents against rat liver fibrosis induced by CCl(4) via inhibition of hepatic stellate cells activation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:12

    Topics: Animals; Blotting, Western; Carbon Tetrachloride Poisoning; Carcinogens; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Hepatic Stellate Cells; Lamiaceae; Liver; Liver Cirrhosis; Liver Function Tests; Male; Matrix Metalloproteinases; Oleanolic Acid; Phytotherapy; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid

2008
Bioassay-guided fractionation of lemon balm (Melissa officinalis L.) using an in vitro measure of GABA transaminase activity.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:8

    Topics: 4-Aminobutyrate Transaminase; Animals; Cinnamates; Depsides; Melissa; Molecular Structure; Oleanolic Acid; Plant Extracts; Rats; Rosmarinic Acid; Triterpenes; Ursolic Acid

2009
[Studies on the triterpenes from loquat leaf (Eriobotrya japonica)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:9

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Molecular Structure; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Rosaceae; Triterpenes; Ursolic Acid

2008
Rapid and novel discrimination and quantification of oleanolic and ursolic acids in complex plant extracts using two-dimensional nuclear magnetic resonance spectroscopy-Comparison with HPLC methods.
    Analytica chimica acta, 2009, Mar-09, Volume: 635, Issue:2

    Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Lamiaceae; Magnetic Resonance Spectroscopy; Oleaceae; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2009
[Study on correlation between effective ingredients of dogwood fruit from genuine producing regions and traits].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:23

    Topics: China; Colchicine; Cornus; Fruit; Oleanolic Acid; Triterpenes; Ursolic Acid

2008
Triterpenic content and chemometric analysis of virgin olive oils from forty olive cultivars.
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: Fruit; Olea; Oleanolic Acid; Olive Oil; Plant Oils; Species Specificity; Triterpenes; Ursolic Acid

2009
[Alpha-glucosidase inhibitors from Luculia pinciana].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:4

    Topics: Acarbose; alpha-Glucosidases; Coumarins; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Inhibitory Concentration 50; Oleanolic Acid; Plant Extracts; Rubiaceae; Triterpenes; Ursolic Acid

2009
Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
    Molecules (Basel, Switzerland), 2009, Jun-04, Volume: 14, Issue:6

    Topics: Betulinic Acid; Chromatography, Gas; Chromatography, High Pressure Liquid; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Triterpenes; Ursolic Acid

2009
Cytotoxic triterpenoids from the stems of Microtropis japonica.
    Journal of natural products, 2009, Volume: 72, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Stems; Taiwan; Triterpenes; Ursolic Acid

2009
Stimulation of glucose uptake by triterpenoids from Weigela subsessilis.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:1

    Topics: Animals; Caprifoliaceae; Cell Line; Cell Survival; Glucose; Insulin; Molecular Structure; Muscle Fibers, Skeletal; Myoblasts; Oleanolic Acid; Plant Extracts; Rats; Triterpenes; Ursolic Acid

2010
Chemical composition of the stem bark and leaves of Ficus pandurata Hance.
    Natural product research, 2009, Volume: 23, Issue:13

    Topics: Betulinic Acid; Ficus; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Plant Leaves; Sitosterols; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stigmasterol; Triterpenes; Ursolic Acid

2009
The influence of cosolvent on the complexation of HP-beta-cyclodextrins with oleanolic acid and ursolic acid.
    AAPS PharmSciTech, 2009, Volume: 10, Issue:4

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Electronic Data Processing; Ethanol; Oleanolic Acid; Solubility; Triterpenes; Ursolic Acid

2009
Oleanolic acid and ursolic acid affect peptidoglycan metabolism in Listeria monocytogenes.
    Antonie van Leeuwenhoek, 2010, Volume: 97, Issue:1

    Topics: Anti-Bacterial Agents; Bacteriolysis; Cell Wall; Humans; Listeria monocytogenes; Metabolic Networks and Pathways; Oleanolic Acid; Peptides; Peptidoglycan; Triterpenes; Ursolic Acid

2010
Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice.
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Kidney; L-Iditol 2-Dehydrogenase; Lactoylglutathione Lyase; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; RNA, Messenger; Triterpenes; Ursolic Acid

2010
Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Adhesion; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA Fragmentation; Humans; Intercellular Adhesion Molecule-1; Liver Neoplasms; Membrane Potentials; Mitochondrial Membranes; Neoplasm Metastasis; Oleanolic Acid; Sodium-Potassium-Exchanging ATPase; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid; Vascular Endothelial Growth Factor A

2010
Synthesis and cytotoxic activity of the N-acetylglucosamine-bearing triterpenoid saponins.
    Carbohydrate research, 2010, Mar-30, Volume: 345, Issue:5

    Topics: Acetylglucosamine; Antineoplastic Agents, Phytogenic; Cell Proliferation; HL-60 Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Oleanolic Acid; Saponins; Stomach Neoplasms; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2010
Effects of chronic administration of Melissa officinalis L. extract on anxiety-like reactivity and on circadian and exploratory activities in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cinnamates; Circadian Rhythm; Depsides; Dose-Response Relationship, Drug; Drug Administration Schedule; Exploratory Behavior; GABA Agonists; Maze Learning; Melissa; Mice; Mice, Inbred C57BL; Oleanolic Acid; Phytotherapy; Plant Components, Aerial; Plant Extracts; Rosmarinic Acid; Triterpenes; Ursolic Acid

2010
Optimization of microwave-assisted extraction followed by RP-HPLC for the simultaneous determination of oleanolic acid and ursolic acid in the fruits of Chaenomeles sinensis.
    Journal of separation science, 2010, Volume: 33, Issue:8

    Topics: Chromatography, High Pressure Liquid; Fruit; Microwaves; Molecular Structure; Oleanolic Acid; Rosaceae; Solvents; Stereoisomerism; Triterpenes; Ursolic Acid

2010
Gas phase isomeric differentiation of oleanolic and ursolic acids associated with heptakis-(2,6-di-O-methyl)-beta-cyclodextrin by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
    Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:4

    Topics: beta-Cyclodextrins; Fourier Analysis; Models, Molecular; Oleanolic Acid; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2010
Oleanolic acid and ursolic acid induce apoptosis in HuH7 human hepatocellular carcinoma cells through a mitochondrial-dependent pathway and downregulation of XIAP.
    Journal of agricultural and food chemistry, 2010, May-26, Volume: 58, Issue:10

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Down-Regulation; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Oleanolic Acid; Triterpenes; Ursolic Acid; X-Linked Inhibitor of Apoptosis Protein

2010
LC-MS method for the simultaneous quantitation of the anti-inflammatory constituents in oregano (Origanum species).
    Journal of agricultural and food chemistry, 2010, Jun-23, Volume: 58, Issue:12

    Topics: Anti-Inflammatory Agents; Chromatography, Liquid; Cinnamates; Depsides; Mass Spectrometry; Oleanolic Acid; Origanum; Plant Extracts; Rosmarinic Acid; Triterpenes; Ursolic Acid

2010
[Simultaneous determination of four active components in Spica Prunellae by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:5

    Topics: Caffeic Acids; Calibration; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Oleanolic Acid; Prunella; Rosmarinic Acid; Triterpenes; Ursolic Acid

2010
Ursolic acid and oleanolic acid, members of pentacyclic triterpenoid acids, suppress TNF-α-induced E-selectin expression by cultured umbilical vein endothelial cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-01, Volume: 17, Issue:14

    Topics: Anti-Inflammatory Agents; Antigens, Surface; Arctostaphylos; Cells, Cultured; E-Selectin; Endothelial Cells; Endothelium, Vascular; Humans; Magnoliopsida; NF-kappa B; Oleanolic Acid; Panax; Plant Extracts; Plant Leaves; Plant Roots; RNA, Messenger; Triterpenes; Tumor Necrosis Factor-alpha; Umbilical Veins; Ursolic Acid

2010
Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.).
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:2

    Topics: Betulinic Acid; Cell Line; Cell Survival; Humans; Immunologic Factors; Interleukin-6; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Rosa; Triterpenes; Ursolic Acid

2011
Cytotoxicity and bioavailability studies on a decoction of Oldenlandia diffusa and its fractions separated by HPLC.
    Journal of ethnopharmacology, 2010, Sep-15, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; HL-60 Cells; Humans; Intestinal Mucosa; Leukemia, Promyelocytic, Acute; Oldenlandia; Oleanolic Acid; Phytotherapy; Triterpenes; Ursolic Acid

2010
Evaluation of the antibacterial activity of the methylene chloride extract of Miconia ligustroides, isolated triterpene acids, and ursolic acid derivatives.
    Pharmaceutical biology, 2010, Volume: 48, Issue:2

    Topics: Anti-Bacterial Agents; Brazil; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Magnetic Resonance Spectroscopy; Medicine, Traditional; Melastomataceae; Methylene Chloride; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Phytotherapy; Plant Components, Aerial; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2010
[Studies on the lowering blood sugar substances from agrimony (II)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:5

    Topics: Agrimonia; Apigenin; Ellagic Acid; Hypoglycemic Agents; Luteolin; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Components, Aerial; Plants, Medicinal; Saponins; Triterpenes; Ursolic Acid

2010
Variation of oleanolic and ursolic acid in the flesh of persimmon fruit among different cultivars.
    Molecules (Basel, Switzerland), 2010, Sep-20, Volume: 15, Issue:9

    Topics: Chromatography, High Pressure Liquid; Diospyros; Fruit; Oleanolic Acid; Species Specificity; Triterpenes; Ursolic Acid

2010
Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. DC. (Asteraceae).
    Parasitology research, 2011, Volume: 108, Issue:3

    Topics: Animals; Baccharis; Caffeic Acids; Cell Line; Chromones; Leishmania braziliensis; Leishmania mexicana; Macrophages; Magnetic Resonance Spectroscopy; Medicine, Traditional; Mice; Nitrates; Nitric Oxide; Oleanolic Acid; Parasitic Sensitivity Tests; Plant Extracts; Plants, Medicinal; Triterpenes; Ursolic Acid

2011
[Effect of different water treatments on quality and yield of spadix in Prunella vulgaris].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:14

    Topics: Oleanolic Acid; Prunella; Triterpenes; Ursolic Acid; Water

2010
[Studies on the chemical constituents of Callicarpa kochiana].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:6

    Topics: Callicarpa; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Leaves; Plant Stems; Plants, Medicinal; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid

2010
[Studies on the triterpenoids of Vitex trifolia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:6

    Topics: Betulinic Acid; Ethanol; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid; Vitex

2010
Antiangiogenic potential of three triterpenic acids in human liver cancer cells.
    Journal of agricultural and food chemistry, 2011, Jan-26, Volume: 59, Issue:2

    Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Fibroblast Growth Factor 2; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Liver Neoplasms; Oleanolic Acid; Triterpenes; Ursolic Acid

2011
Clarification of the phenotypic characteristics and anti-tumor activity of Hedyotis diffusa.
    The American journal of Chinese medicine, 2011, Volume: 39, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Drug Contamination; Hedyotis; Humans; Neoplasms; Oleanolic Acid; Phenotype; Phytotherapy; Plant Extracts; Quality Control; Species Specificity; Triterpenes; Ursolic Acid

2011
Oleanolic and ursolic acids influence affect the expression of the cysteine regulon and the stress response in Escherichia coli.
    Current microbiology, 2011, Volume: 62, Issue:4

    Topics: Cysteine; Escherichia coli; Gene Expression Regulation, Bacterial; Oleanolic Acid; Regulon; Stress, Physiological; Triterpenes; Ursolic Acid

2011
Suppression of hepatitis B virus x protein-mediated tumorigenic effects by ursolic Acid.
    Journal of agricultural and food chemistry, 2011, Mar-09, Volume: 59, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cell Line, Tumor; Flavones; Hepatocytes; Humans; Liver Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; Oleanolic Acid; Signal Transduction; Trans-Activators; Transcriptional Activation; Transfection; Triterpenes; Ursolic Acid; Viral Regulatory and Accessory Proteins

2011
Highly sensitive and selective pre-column derivatization high-performance liquid chromatography approach for rapid determination of triterpenes oleanolic and ursolic acids and application to Swertia species: optimization of triterpenic acids extraction an
    Analytica chimica acta, 2011, Mar-04, Volume: 688, Issue:2

    Topics: Acridines; Benzenesulfonates; Chromatography, High Pressure Liquid; Limit of Detection; Mass Spectrometry; Oleanolic Acid; Reproducibility of Results; Solid Phase Extraction; Swertia; Triterpenes; Ursolic Acid

2011
Herbaceous peony (Paeonia lactiflora Pall.) as an alternative source of oleanolic and ursolic acids.
    International journal of molecular sciences, 2011, Jan-18, Volume: 12, Issue:1

    Topics: Chromatography, High Pressure Liquid; Oleanolic Acid; Paeonia; Plant Leaves; Triterpenes; Ursolic Acid

2011
Antileishmanial activity of the hydroalcoholic extract of Miconia langsdorffii, isolated compounds, and semi-synthetic derivatives.
    Molecules (Basel, Switzerland), 2011, Feb-22, Volume: 16, Issue:2

    Topics: Animals; Antiprotozoal Agents; Biological Assay; Leishmania; Melastomataceae; Molecular Structure; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid

2011
Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescent Dyes; Food Analysis; Fruit; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2011
Oleanolic acid and ursolic acid derived from Cornus officinalis Sieb. et Zucc. suppress epidermal growth factor- and phorbol ester-induced MUC5AC mucin production and gene expression from human airway epithelial cells.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:5

    Topics: Anti-Infective Agents; Cell Line, Tumor; Cornus; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Epithelial Cells; Gene Expression Regulation; Humans; Mucin 5AC; Oleanolic Acid; Phorbol Esters; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Triterpenes; Ursolic Acid

2011
Identification and quantification of oleanolic acid and ursolic acid in Chinese herbs by liquid chromatography-ion trap mass spectrometry.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:12

    Topics: Chromatography, Liquid; Drugs, Chinese Herbal; Eriobotrya; Glycyrrhetinic Acid; Linear Models; Mass Spectrometry; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Triterpenes; Ursolic Acid

2011
Molecular cloning and expression of squalene synthase and 2,3-oxidosqualene cyclase genes in persimmon (Diospyros kaki L.) fruits.
    Molecular biology reports, 2012, Volume: 39, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Biosynthetic Pathways; China; Cloning, Molecular; Computational Biology; Diospyros; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Fruit; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; Oligonucleotides; Open Reading Frames; Pentacyclic Triterpenes; Phylogeny; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Triterpenes; Ursolic Acid

2012
[Dynamic change of active component content in different parts of Prunella vulgaris].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:6

    Topics: Chromatography, High Pressure Liquid; Flavonoids; Oleanolic Acid; Prunella; Triterpenes; Ursolic Acid

2011
[Simultaneous determination of acteoside, oleanolic acid and ursolic acid in flower of Campsis grandiflora by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:8

    Topics: Bignoniaceae; Chromatography, High Pressure Liquid; Flowers; Glucosides; Oleanolic Acid; Phenols; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid

2011
[Studies on the chemical constituents of Artemisia lavandulaefolia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:2

    Topics: Artemisia; Flavones; Molecular Structure; Oleanolic Acid; Plant Components, Aerial; Plants, Medicinal; Sitosterols; Triterpenes; Ursolic Acid

2011
Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro.
    Chinese journal of integrative medicine, 2011, Volume: 17, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Oleanolic Acid; Triterpenes; Ursolic Acid

2011
Isolation of modulators of the liver-specific organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae).
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Estradiol; Estrone; Hepatocytes; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Molecular Targeted Therapy; Oleanolic Acid; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Plant Bark; Plant Extracts; Rollinia; Solute Carrier Organic Anion Transporter Family Member 1B3; Terpenes; Triterpenes; Ursolic Acid

2011
Rapid access to ketones related to oleanolic and ursolic acids.
    Natural product research, 2012, Volume: 26, Issue:7

    Topics: Crystallography, X-Ray; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Oleanolic Acid; Oxidation-Reduction; Salvia; Triterpenes; Ursolic Acid

2012
Microwave-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait.
    International journal of molecular sciences, 2011, Volume: 12, Issue:8

    Topics: Chemical Fractionation; Ligustrum; Microwaves; Molecular Structure; Oleanolic Acid; Plant Extracts; Solvents; Temperature; Triterpenes; Ursolic Acid

2011
Two new triterpenoid glycosides from the leaves of Anthocephalus chinensis.
    Journal of Asian natural products research, 2011, Volume: 13, Issue:11

    Topics: Drugs, Chinese Herbal; Glucosides; Glycosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Leaves; Rubiaceae; Saponins; Stereoisomerism; Triterpenes; Ursolic Acid

2011
Determination of oleanolic and ursolic acid in Chinese herbs using HPLC and γ-CD as mobile phase modifier.
    Journal of separation science, 2011, Volume: 34, Issue:21

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Oleanolic Acid; Oligosaccharides; Triterpenes; Ursolic Acid

2011
A new languidulane diterpenoid from Salvia mexicana var. mexicana.
    Molecules (Basel, Switzerland), 2011, Oct-21, Volume: 16, Issue:10

    Topics: Arbutin; Diterpenes; Flavanones; Lamiaceae; Magnetic Resonance Spectroscopy; Oleanolic Acid; Plant Components, Aerial; Plant Extracts; Salvia; Triterpenes; Ursolic Acid

2011
CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.
    Plant & cell physiology, 2011, Volume: 52, Issue:12

    Topics: Amino Acid Sequence; Betulinic Acid; Biosynthetic Pathways; Cloning, Molecular; Cytochrome P-450 Enzyme System; Intramolecular Transferases; Medicago truncatula; Multienzyme Complexes; Oleanolic Acid; Pentacyclic Triterpenes; Phylogeny; Saccharomyces cerevisiae; Triterpenes; Ursolic Acid; Vitis

2011
Effects of Lecythis pisonis Camb. (Lecythidaceae) in a mouse model of pruritus.
    Journal of ethnopharmacology, 2012, Jan-06, Volume: 139, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Carrageenan; Cell Degranulation; Disease Models, Animal; Edema; Ethanol; Ether; Female; Lecythidaceae; Male; Mast Cells; Medicine, Traditional; Mice; Motor Activity; Oleanolic Acid; p-Methoxy-N-methylphenethylamine; Phytotherapy; Plant Extracts; Plant Leaves; Pruritus; Rats; Rats, Wistar; Solvents; South America; Triterpenes; Ursolic Acid

2012
Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Abietanes; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Lethal Dose 50; Mice; Motor Activity; Narcotic Antagonists; Oleanolic Acid; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Plants, Medicinal; Salvia officinalis; Time Factors; Triterpenes; Ursolic Acid

2012
Triterpene acids from rose hip powder inhibit self-antigen- and LPS-induced cytokine production and CD4⁺ T-cell proliferation in human mononuclear cell cultures.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:8

    Topics: Acids; Autoantigens; B-Lymphocytes; Betulinic Acid; CD4-Positive T-Lymphocytes; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Immunologic; Flow Cytometry; Humans; Immunologic Factors; Inhibitory Concentration 50; Interleukin-10; Lipopolysaccharides; Oleanolic Acid; Pentacyclic Triterpenes; Plant Preparations; Rosa; Thyroglobulin; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2012
Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait.
    Ultrasonics sonochemistry, 2012, Volume: 19, Issue:4

    Topics: Fruit; Ligustrum; Molecular Structure; Oleanolic Acid; Solvents; Sonication; Triterpenes; Ursolic Acid

2012
Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation.
    Journal of cellular physiology, 2012, Volume: 227, Issue:10

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Oldenlandia; Oleanolic Acid; Plant Extracts; Promoter Regions, Genetic; Tamoxifen; Transcriptional Activation; Triterpenes; Tumor Suppressor Protein p53; Up-Regulation; Ursolic Acid

2012
Triterpenoid acids and lactones from the leaves of Fadogia tetraquetra var. tetraquetra (Rubiaceae).
    Natural product communications, 2011, Volume: 6, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cricetinae; Humans; Lactones; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Plant Leaves; Rubiaceae; Triterpenes; Ursolic Acid

2011
The effect of ursolic and oleanolic acids on human skin fibroblast cells.
    Folia histochemica et cytobiologica, 2011, Volume: 49, Issue:4

    Topics: Actins; Cell Proliferation; Cytotoxins; Dose-Response Relationship, Drug; Fibroblasts; Free Radicals; Humans; Oleanolic Acid; Skin; Triterpenes; Ursolic Acid

2011
Modulation of antibiotic resistance in bacterial pathogens by oleanolic acid and ursolic acid.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Apr-15, Volume: 19, Issue:6

    Topics: Anti-Bacterial Agents; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Listeria monocytogenes; Oleanolic Acid; Phytotherapy; Plant Extracts; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Triterpenes; Ursolic Acid

2012
A rapid LC/MS/MS method for the analysis of nonvolatile antiinflammatory agents from Mentha spp.
    Journal of food science, 2011, Volume: 76, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Chemical Phenomena; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Distillation; Industrial Waste; Macrophage Activation; Mentha; Mice; Oils, Volatile; Oleanolic Acid; Plant Components, Aerial; Plant Extracts; Reproducibility of Results; Rosmarinic Acid; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2011
Triterpenes from Callicarpa integerrima Champ.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:1

    Topics: Betulinic Acid; Callicarpa; Molecular Conformation; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Plant Stems; Plants, Medicinal; Saponins; Triterpenes; Ursolic Acid

2012
Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavones; Fluorescent Antibody Technique; Glucose-6-Phosphate Isomerase; Humans; Immunoprecipitation; Liver Neoplasms; Luciferases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Mice; Mice, Nude; Neovascularization, Pathologic; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2013
Changes in bioactive components related to the harvest time from the spicas of Prunella vulgaris.
    Pharmaceutical biology, 2012, Volume: 50, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; China; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Electrochemical Techniques; Ethnopharmacology; Flowering Tops; Oleanolic Acid; Plants, Medicinal; Prunella; Rosmarinic Acid; Seasons; Triterpenes; Ursolic Acid

2012
Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice.
    The American journal of Chinese medicine, 2012, Volume: 40, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Elaeagnaceae; Flavonoids; Flavonols; Formaldehyde; Inflammation; Inflammation Mediators; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oleanolic Acid; Pain; Phytotherapy; Plant Extracts; Polyphenols; Triterpenes; Ursolic Acid

2012
[Influence of storage period and grading standards on quality of Prunella vulgaris].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7

    Topics: China; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Drug Storage; Flavonoids; Oleanolic Acid; Polysaccharides; Prunella; Rosmarinic Acid; Triterpenes; Ursolic Acid

2012
Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Anticarcinogenic Agents; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoenzymes; Oleanolic Acid; Precursor Cells, B-Lymphoid; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid

2012
Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus.
    Planta, 2012, Volume: 236, Issue:5

    Topics: Arabidopsis; Biosynthetic Pathways; Catharanthus; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA, Complementary; Expressed Sequence Tags; Gene Expression Regulation, Plant; Intramolecular Transferases; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Plant Proteins; Plants, Medicinal; Saccharomyces cerevisiae; Triterpenes; Ursolic Acid

2012
In vitro anti-breast cancer activity of ethanolic extract of Wrightia tomentosa: role of pro-apoptotic effects of oleanolic acid and urosolic acid.
    Journal of ethnopharmacology, 2012, Jun-26, Volume: 142, Issue:1

    Topics: Antineoplastic Agents; Apocynaceae; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ethanol; HEK293 Cells; Humans; L-Lactate Dehydrogenase; Oleanolic Acid; Plant Extracts; Plant Leaves; Solvents; Triterpenes; Ursolic Acid

2012
Rapid identification of molecular changes in tulsi (Ocimum sanctum Linn) upon ageing using leaf spray ionization mass spectrometry.
    The Analyst, 2012, Oct-07, Volume: 137, Issue:19

    Topics: Methanol; Ocimum; Oleanolic Acid; Oxidation-Reduction; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Time Factors; Triterpenes; Ursolic Acid

2012
In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids.
    Journal of agricultural and food chemistry, 2012, Sep-19, Volume: 60, Issue:37

    Topics: Animals; Apoptosis; Breast Neoplasms; Caco-2 Cells; Cell Cycle; Cell Proliferation; Female; Fruit; Hep G2 Cells; Humans; Malus; Mammary Neoplasms, Animal; MCF-7 Cells; NF-kappa B; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Triterpenes; Ursolic Acid

2012
Simultaneous determination of phenolic compounds and triterpenic acids in oregano growing wild in Greece by 31P NMR spectroscopy.
    Magnetic resonance in chemistry : MRC, 2012, Volume: 50, Issue:11

    Topics: Greece; Magnetic Resonance Spectroscopy; Oleanolic Acid; Origanum; Phenols; Phosphorus Isotopes; Triterpenes; Ursolic Acid

2012
Bioactive oleanane, lupane and ursane triterpene acid derivatives.
    Molecules (Basel, Switzerland), 2012, Oct-17, Volume: 17, Issue:10

    Topics: Animals; Artemia; Betulinic Acid; Esters; Free Radical Scavengers; Lamiaceae; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Triterpenes; Ursolic Acid

2012
Variation in concentrations of major bioactive compounds in Prunella vulgaris L. related to plant parts and phenological stages.
    Biological research, 2012, Volume: 45, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cinnamates; Depsides; Fruit; Oleanolic Acid; Plant Extracts; Plant Leaves; Plant Stems; Prunella; Rosmarinic Acid; Triterpenes; Ursolic Acid

2012
The in vitro study of ursolic acid and oleanolic acid inhibiting cariogenic microorganisms as well as biofilm.
    Oral diseases, 2013, Volume: 19, Issue:5

    Topics: Actinomyces; Anti-Infective Agents; Biofilms; Dental Caries; Microbial Sensitivity Tests; Oleanolic Acid; Streptococcus; Triterpenes; Ursolic Acid

2013
A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.
    Food chemistry, 2013, Jan-15, Volume: 136, Issue:2

    Topics: Betulinic Acid; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plants; Triterpenes; Ursolic Acid

2013
Bioactive constituents of Salvia chrysophylla Stapf.
    Natural product research, 2013, Volume: 27, Issue:4-5

    Topics: Antioxidants; Cholinesterase Inhibitors; Diterpenes; Flavones; Lamiaceae; Lipid Peroxidation; Methylene Chloride; Oleanolic Acid; Plant Extracts; Salvia; Triterpenes; Ursolic Acid

2013
[Determination of oleanolic acid and ursolic acid in Damnacanthus indicus from different places by RP-hPLC].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:5

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Oleanolic Acid; Plants, Medicinal; Quality Control; Reproducibility of Results; Rubiaceae; Triterpenes; Ursolic Acid

2012
Oleanolic acid and ursolic acid: novel hepatitis C virus antivirals that inhibit NS5B activity.
    Antiviral research, 2013, Volume: 98, Issue:1

    Topics: Antiviral Agents; Cell Line; Down-Regulation; Drugs, Chinese Herbal; Hepacivirus; Hepatitis C; Humans; Ligustrum; Oleanolic Acid; Replicon; Triterpenes; Ursolic Acid; Viral Nonstructural Proteins; Virus Replication

2013
In vivo activity of ursolic and oleanolic acids during the acute phase of Trypanosoma cruzi infection.
    Experimental parasitology, 2013, Volume: 134, Issue:4

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Infective Agents; Chagas Disease; Disease Models, Animal; Infusions, Parenteral; Interferon-gamma; Interleukin-10; Male; Melastomataceae; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oleanolic Acid; Parasitemia; Random Allocation; Triterpenes; Trypanocidal Agents; Ursolic Acid

2013
Processing technology investigation of loquat (Eriobotrya japonica) leaf by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry combined with chemometrics.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Chromatography, Liquid; Discriminant Analysis; Eriobotrya; Honey; Ions; Least-Squares Analysis; Mass Spectrometry; Multivariate Analysis; Oleanolic Acid; Plant Leaves; Principal Component Analysis; Reproducibility of Results; Triterpenes; Ursolic Acid

2013
[Chemical constituents of Gentiana rhodantha].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:3

    Topics: Chromatography, Gel; Chromatography, Reverse-Phase; Dextrans; Gentianaceae; Mass Spectrometry; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Quercetin; Salicylic Acid; Silica Gel; Triterpenes; Ursolic Acid; Xanthones

2013
α-Glucosidase inhibitory triterpenoids from the stem barks of Uncaria laevigata.
    Fitoterapia, 2013, Volume: 90

    Topics: Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Inhibitory Concentration 50; Molecular Structure; Oleanolic Acid; Plant Bark; Plant Extracts; Plant Stems; Triterpenes; Uncaria; Ursolic Acid

2013
Two new chiratane-type triterpenoids from Swertia kouitchensis.
    Molecules (Basel, Switzerland), 2013, Jul-18, Volume: 18, Issue:7

    Topics: Glycoside Hydrolase Inhibitors; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Extracts; Saccharomyces cerevisiae; Swertia; Triterpenes; Ursolic Acid

2013
Optimisation of potassium chloride nutrition for proper growth, physiological development and bioactive component production in Prunella vulgaris L.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Chlorophyll; Cinnamates; Depsides; Flavonoids; Nitrogen; Oleanolic Acid; Photosynthesis; Plant Leaves; Plants, Medicinal; Potassium; Potassium Chloride; Prunella; Rosmarinic Acid; Triterpenes; Ursolic Acid; Water

2013
Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment.
    BMC complementary and alternative medicine, 2013, Oct-07, Volume: 13

    Topics: Analysis of Variance; Animals; Antitubercular Agents; Arecaceae; Bacterial Load; Colony Count, Microbial; Drug Synergism; Immunologic Factors; Lantana; Lung; Male; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Oleanolic Acid; Plants, Medicinal; Triterpenes; Tuberculosis, Pulmonary; Ursolic Acid

2013
[Chemical constituents of Dipsacus asper].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:7

    Topics: Dipsacaceae; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Triterpenes; Ursolic Acid

2013
Treatment with triterpenic fraction purified from Baccharis uncinella leaves inhibits Leishmania (Leishmania) amazonensis spreading and improves Th1 immune response in infected mice.
    Parasitology research, 2014, Volume: 113, Issue:1

    Topics: Amphotericin B; Animals; Baccharis; Immunity, Cellular; Interferon-gamma; Interleukin-12; Leishmania; Leishmaniasis, Cutaneous; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; Parasite Load; Plant Extracts; Plant Leaves; Th1 Cells; Triterpenes; Ursolic Acid

2014
[Active components of Ligustrum lucidum inhibiting hepatitis C virus replicase activity].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:9

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Ligustrum; Oleanolic Acid; Plants, Medicinal; Triterpenes; Ursolic Acid; Viral Nonstructural Proteins

2013
The chemical and biological potential of C ring modified triterpenoids.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; MCF-7 Cells; Mice; Molecular Conformation; NIH 3T3 Cells; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2014
Anticancer activity of the roots of Ichnocarpus frutescens R. Br. and isolated triterpenes.
    Pakistan journal of pharmaceutical sciences, 2014, Volume: 27, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apocynaceae; Cell Line, Tumor; Humans; Oleanolic Acid; Plant Extracts; Plant Roots; Triterpenes; Ursolic Acid

2014
Bioavailability and activity of natural food additive triterpenoids as influenced by protein.
    Journal of agricultural and food chemistry, 2014, Mar-12, Volume: 62, Issue:10

    Topics: Anilino Naphthalenesulfonates; Binding Sites; Biological Availability; Circular Dichroism; Fluorescence; Food Additives; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Dynamics Simulation; Oleanolic Acid; Protein Conformation; Serum Albumin, Bovine; Thermodynamics; Triterpenes; Ursolic Acid

2014
Development and validation of a modified ultrasound-assisted extraction method and a HPLC method for the quantitative determination of two triterpenic acids in Hedyotis diffusa.
    Natural product communications, 2013, Volume: 8, Issue:12

    Topics: Chromatography, High Pressure Liquid; Hedyotis; Oleanolic Acid; Sound; Triterpenes; Ursolic Acid

2013
Oleanolic acid and ursolic acid inhibit proliferation in transformed rat hepatic oval cells.
    World journal of gastroenterology, 2014, Feb-07, Volume: 20, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Transformed; Cell Proliferation; Cell Shape; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; G1 Phase Cell Cycle Checkpoints; Hydrogen Peroxide; Liver; Oleanolic Acid; Oxidative Stress; Rats; Stem Cells; Time Factors; Triterpenes; Ursolic Acid

2014
Determination of triterpenic acids and screening for valuable secondary metabolites in Salvia sp. suspension cultures.
    Natural product communications, 2014, Volume: 9, Issue:1

    Topics: Cells, Cultured; Oleanolic Acid; Salvia; Triterpenes; Ursolic Acid

2014
The synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin.
    Molecules (Basel, Switzerland), 2014, Apr-17, Volume: 19, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Synergism; Female; gamma-Cyclodextrins; Humans; Melanoma; Mice; Oleanolic Acid; Skin Neoplasms; Solubility; Triterpenes; Ultraviolet Rays; Ursolic Acid

2014
An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives.
    Organic & biomolecular chemistry, 2014, Jul-28, Volume: 12, Issue:28

    Topics: Animals; Anti-Infective Agents; Cell Line; Esters; Inhibitory Concentration 50; Interferon-gamma; Macrophages; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2014
Triterpenes as uncompetitive inhibitors of α-glucosidase from flowers of Punica granatum L.
    Natural product research, 2014, Volume: 28, Issue:23

    Topics: alpha-Glucosidases; Coumaric Acids; Dose-Response Relationship, Drug; Flowers; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lythraceae; Oleanolic Acid; Propionates; Sitosterols; Triterpenes; Ursolic Acid

2014
Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human Solute Carrier transporters.
    Pharmaceutical biology, 2014, Volume: 52, Issue:12

    Topics: Dose-Response Relationship, Drug; Gallic Acid; HEK293 Cells; Herb-Drug Interactions; Humans; Inhibitory Concentration 50; Kidney; Liver; Lythraceae; Oleanolic Acid; Organic Anion Transporters; Organic Cation Transport Proteins; Triterpenes; Ursolic Acid

2014
The effect of oleanolic and ursolic acids on the hemolytic properties and biofilm formation of Listeria monocytogenes.
    Polish journal of microbiology, 2014, Volume: 63, Issue:1

    Topics: Bacterial Toxins; Biofilms; Gene Expression Regulation, Bacterial; Heat-Shock Proteins; Hemolysin Proteins; Hemolysis; Listeria monocytogenes; Microbial Sensitivity Tests; Oleanolic Acid; Triterpenes; Ursolic Acid; Virulence

2014
Simultaneous determination of oleanolic acid, ursolic acid, quercetin and apigenin in Swertia mussotii Franch by capillary zone electrophoresis with running buffer modifier.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3

    Topics: Apigenin; beta-Cyclodextrins; Buffers; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Limit of Detection; Oleanolic Acid; Plants, Medicinal; Quercetin; Reproducibility of Results; Swertia; Tablets; Time Factors; Triterpenes; Ultraviolet Rays; Ursolic Acid

2015
Inhibition of human enterovirus 71 replication by pentacyclic triterpenes and their novel synthetic derivatives.
    Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:8

    Topics: Antiviral Agents; Enterovirus A, Human; Enterovirus Infections; Humans; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid; Virus Replication

2014
Chemical constituents of gold-red apple and their α-glucosidase inhibitory activities.
    Journal of food science, 2014, Volume: 79, Issue:10

    Topics: alpha-Glucosidases; alpha-Linolenic Acid; Betulinic Acid; Fruit; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Malus; Oleanolic Acid; Pentacyclic Triterpenes; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2014
Studies of the interactions of ursane-type bioactive terpenes with the model of Escherichia coli inner membrane-Langmuir monolayer approach.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:2

    Topics: Cardiolipins; Cell Membrane; Escherichia coli; Hydrophobic and Hydrophilic Interactions; Kinetics; Membranes, Artificial; Oleanolic Acid; Phosphatidylethanolamines; Phosphatidylglycerols; Static Electricity; Thermodynamics; Triterpenes; Ursolic Acid

2015
[Chemical constituents from roots of Rubus parvifolius].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:6

    Topics: Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Oleanolic Acid; Plant Roots; Rubus; Sitosterols; Triterpenes; Ursolic Acid

2014
Determination of ursolic and oleanolic acid in Sambuci fructus.
    Chemistry & biodiversity, 2014, Volume: 11, Issue:12

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Mass Spectrometry; Oleanolic Acid; Proton Magnetic Resonance Spectroscopy; Sambucus; Triterpenes; Ursolic Acid

2014
Supercritical fluid extraction of heather (Calluna vulgaris) and evaluation of anti-hepatitis C virus activity of the extracts.
    Virus research, 2015, Feb-16, Volume: 198

    Topics: Antiviral Agents; Calluna; Cell Line; Cell Survival; Chromatography, Supercritical Fluid; Hepacivirus; Hepatocytes; Humans; Hydrostatic Pressure; Microbial Viability; Oleanolic Acid; Plant Extracts; Temperature; Triterpenes; Ursolic Acid

2015
Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liquid Phase Microextraction; Medicine, Chinese Traditional; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Solvents; Triterpenes; Ultrasonics; Ursolic Acid

2015
Quantitative determination of three pentacyclic triterpenes from five Swertia L. species endemic to Western Ghats, India, using RP-HPLC analysis.
    Natural product research, 2015, Volume: 29, Issue:19

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; India; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Species Specificity; Swertia; Triterpenes; Ursolic Acid

2015
Development and validation of a high-performance liquid chromatography method for the quantification of ursolic/oleanic acids mixture isolated from Plumeria obtusa.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Mar-01, Volume: 983-984

    Topics: Apocynaceae; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Oleanolic Acid; Permeability; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Triterpenes; Ursolic Acid

2015
Design and optimization of oleanolic/ursolic acid-loaded nanoplatforms for ocular anti-inflammatory applications.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Drug Delivery Systems; Drug Design; Drug Evaluation, Preclinical; Eye Diseases; Nanoparticles; Oleanolic Acid; Rabbits; Triterpenes; Ursolic Acid

2015
Simultaneous Determination of Oleanolic and Ursolic Acids in Rat Plasma by HPLC-MS: Application to a Pharmacokinetic Study After Oral Administration of Different Combinations of QingGanSanJie Decoction Extracts.
    Journal of chromatographic science, 2015, Volume: 53, Issue:7

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limit of Detection; Liquid-Liquid Extraction; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2015
Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells.
    Journal of natural products, 2015, Apr-24, Volume: 78, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Breast Neoplasms; Drug Resistance, Neoplasm; Genes, erbB-1; Humans; Leupeptins; Molecular Structure; NF-kappa B; Oleanolic Acid; Pharmacogenetics; Plants, Medicinal; Salvia officinalis; Signal Transduction; Triterpenes; Ursolic Acid

2015
Terpenoids of Linaria alpina (L.) Mill. from Dolomites, Italy.
    Natural product research, 2015, Volume: 29, Issue:21

    Topics: Flavonoids; Iridoid Glucosides; Italy; Linaria; Molecular Structure; Oleanolic Acid; Phytochemicals; Plant Components, Aerial; Plant Extracts; Terpenes; Triterpenes; Ursolic Acid

2015
Grazing incidence diffraction studies of the interactions between ursane-type antimicrobial triterpenes and bacterial anionic phospholipids.
    Colloids and surfaces. B, Biointerfaces, 2015, Apr-01, Volume: 128

    Topics: Anti-Infective Agents; Cardiolipins; Crystallization; Escherichia coli; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Oleanolic Acid; Phosphatidylglycerols; Thermodynamics; Triterpenes; Ursolic Acid

2015
Nanoemulsions for dermal controlled release of oleanolic and ursolic acids: In vitro, ex vivo and in vivo characterization.
    Colloids and surfaces. B, Biointerfaces, 2015, Jun-01, Volume: 130

    Topics: Administration, Cutaneous; Delayed-Action Preparations; Drug Delivery Systems; Drug Stability; Emulsions; Humans; Kinetics; Microscopy, Electron, Transmission; Nanoparticles; Oleanolic Acid; Skin; Skin Absorption; Solubility; Temperature; Triterpenes; Ursolic Acid; Viscosity

2015
Ursolic acid and oleanolic acid from Eriobotrya fragrans inhibited the viability of A549 cells.
    Natural product communications, 2015, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Eriobotrya; Humans; Oleanolic Acid; Triterpenes; Ursolic Acid

2015
A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica).
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Apr-15, Volume: 22, Issue:4

    Topics: Acid Phosphatase; Animals; Bone Resorption; Cell Line; Eriobotrya; Isoenzymes; Mice; Molecular Structure; Oleanolic Acid; Osteoclasts; Plant Leaves; Structure-Activity Relationship; Tartrate-Resistant Acid Phosphatase; Triterpenes; Ursolic Acid

2015
Optimization of carvacrol, rosmarinic, oleanolic and ursolic acid extraction from oregano herbs (Origanum onites L., Origanum vulgare spp. hirtum and Origanum vulgare L.).
    Natural product research, 2016, Volume: 30, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cinnamates; Cymenes; Depsides; Molecular Structure; Monoterpenes; Oleanolic Acid; Origanum; Plant Extracts; Rosmarinic Acid; Solvents; Triterpenes; Ursolic Acid

2016
New pimarane diterpenes and other antimycobacterial metabolites from Anisochilus verticillatus.
    Natural product research, 2016, Volume: 30, Issue:6

    Topics: Abietanes; Antitubercular Agents; Crystallography, X-Ray; Eugenol; Lamiaceae; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oleanolic Acid; Triterpenes; Ursolic Acid

2016
Factors affecting the content of the ursolic and oleanolic acid in apple peel: influence of cultivars, sun exposure, storage conditions, bruising and Penicillium expansum infection.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:6

    Topics: Food Storage; Fruit; Hydrogen-Ion Concentration; Malus; Oleanolic Acid; Penicillium; Sunlight; Time Factors; Triterpenes; Ursolic Acid

2016
Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159.
    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Gene Expression Regulation, Bacterial; Oleanolic Acid; Peptidoglycan; Streptococcus mutans; Triterpenes; Ursolic Acid

2015
Macrophage Activation by Ursolic and Oleanolic Acids during Mycobacterial Infection.
    Molecules (Basel, Switzerland), 2015, Aug-06, Volume: 20, Issue:8

    Topics: Animals; Cell Culture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Macrophage Activation; Macrophages; Mice; Mycobacterium tuberculosis; Nitric Oxide; Oleanolic Acid; Reactive Oxygen Species; Transforming Growth Factor beta1; Triterpenes; Tuberculosis; Tumor Necrosis Factor-alpha; Ursolic Acid

2015
Two New Compounds from Hedyotis lindleyana.
    Natural product communications, 2015, Volume: 10, Issue:7

    Topics: Hedyotis; Imidazoles; Iridoids; Molecular Structure; Oleanolic Acid; Pyrans; Triterpenes; Ursolic Acid

2015
[Study on Chemical Composition of Phyllanthus emblica].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:2

    Topics: Betulinic Acid; Gallic Acid; Oleanolic Acid; Pentacyclic Triterpenes; Phyllanthus emblica; Phytochemicals; Plants, Medicinal; Quercetin; Rutin; Triterpenes; Ursolic Acid

2015
[Chemical Constituents from Melissa officinalis Leaves].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:3

    Topics: Benzaldehydes; Cinnamates; Depsides; Melissa; Oleanolic Acid; Palmitic Acid; Phytochemicals; Plant Extracts; Rosmarinic Acid; Sitosterols; Triterpenes; Ursolic Acid

2015
The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Female; Leishmania; Leishmaniasis, Cutaneous; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Oleanolic Acid; Plant Extracts; Triterpenes; Trypanocidal Agents; Ursolic Acid

2015
[Establishment of quality standard for Corni Fructus based on the multiple bioactive constituents].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:15

    Topics: Cornus; Drug Stability; Oleanolic Acid; Quality Control; Triterpenes; Ursolic Acid

2015
Human neutrophil elastase inhibition studied by capillary electrophoresis with laser induced fluorescence detection and microscale thermophoresis.
    Journal of chromatography. A, 2016, Jan-29, Volume: 1431

    Topics: Chemistry Techniques, Analytical; Diffusion; Electrophoresis, Capillary; Enzyme Activation; Fluorescence; Humans; Kinetics; Lasers; Leukocyte Elastase; Oleanolic Acid; Pentacyclic Triterpenes; Reproducibility of Results; Serpins; Triterpenes; Ursolic Acid

2016
"Fungal elicitors combined with a sucrose feed significantly enhance triterpene production of a Salvia fruticosa cell suspension".
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:16

    Topics: Aspergillus niger; Bioreactors; Cell Culture Techniques; Culture Media, Conditioned; Cyclopentanes; Oleanolic Acid; Oxylipins; Plant Cells; Salvia; Sucrose; Trichoderma; Triterpenes; Ursolic Acid

2016
A new anthraquinone and eight constituents from Hedyotis caudatifolia Merr. et Metcalf: isolation, purification and structural identification.
    Natural product research, 2016, Volume: 30, Issue:19

    Topics: Anthraquinones; China; Hedyotis; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Sitosterols; Stigmasterol; Triterpenes; Ursolic Acid

2016
Anti-inflammatory and toxicological evaluation of Moussonia deppeana (Schldl. & Cham) Hanst and Verbascoside as a main active metabolite.
    Journal of ethnopharmacology, 2016, Jul-01, Volume: 187

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrageenan; Edema; Female; Glucosides; Magnoliopsida; Male; Medicine, Traditional; Mexico; Mice, Inbred BALB C; Oleanolic Acid; Phenols; Phorbol Esters; Phytochemicals; Phytotherapy; Picrates; Plant Components, Aerial; Plant Extracts; Triterpenes; Ursolic Acid

2016
Determination of betulinic acid, oleanolic acid and ursolic acid from Achyranthes aspera L. using RP-UFLC-DAD analysis and evaluation of various parameters for their optimum yield.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:3

    Topics: Achyranthes; Betulinic Acid; Chromatography, Reverse-Phase; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2016
Anti-proliferative and antibacterial in vitro evaluation of the polyurethane nanostructures incorporating pentacyclic triterpenes.
    Pharmaceutical biology, 2016, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Humans; Microscopy, Electron, Scanning; Nanostructures; Oleanolic Acid; Particle Size; Polyurethanes; Triterpenes; Ursolic Acid

2016
[Chemical Constituents from Camellia oleifera Stem].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:10

    Topics: Betulinic Acid; Camellia; Drugs, Chinese Herbal; Flavonoids; Furans; Lignans; Oleanolic Acid; Pentacyclic Triterpenes; Phytochemicals; Plant Stems; Plants, Medicinal; Triterpenes; Ursolic Acid

2015
Inhibitory effect of ursolic acid and oleanolic acid from Eriobotrya fragrans on A549 cell viability in vivo.
    Genetics and molecular research : GMR, 2016, May-13, Volume: 15, Issue:2

    Topics: A549 Cells; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cell Survival; Eriobotrya; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Plant Leaves; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays

2016
Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis.
    Journal of food science, 2016, Volume: 81, Issue:8

    Topics: alpha-Glucosidases; Antioxidants; Biphenyl Compounds; Catechin; China; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonoids; Fruit; Gallic Acid; Glycoside Hydrolase Inhibitors; Oleanolic Acid; Phenols; Picrates; Plant Extracts; Proanthocyanidins; Propionates; Rosaceae; Rutin; Saponins; Species Specificity; Triterpenes; Ursolic Acid; Vanillic Acid

2016
Improvement of ursolic and oleanolic acids' antitumor activity by complexation with hydrophilic cyclodextrins.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; gamma-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Mice; Molecular Docking Simulation; Oleanolic Acid; Triterpenes; Ursolic Acid; X-Ray Diffraction

2016
In vitro inhibition of UGT1A3, UGT1A4 by ursolic acid and oleanolic acid and drug-drug interaction risk prediction.
    Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:9

    Topics: Drug Interactions; Glucuronosyltransferase; Hymecromone; Kinetics; Microsomes, Liver; Oleanolic Acid; Protein Isoforms; Triterpenes; Ursolic Acid

2017
Comparison of the interaction between lactoferrin and isomeric drugs.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Feb-15, Volume: 173

    Topics: Animals; Binding Sites; Cattle; Energy Transfer; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isomerism; Lactoferrin; Metals; Models, Molecular; Molecular Docking Simulation; Oleanolic Acid; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Triterpenes; Tryptophan; Ursolic Acid

2017
Microcrystalline cellulose based matrix solid phase dispersion microextration for isomeric triterpenoid acids in loquat leaves by ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry.
    Journal of chromatography. A, 2016, Nov-11, Volume: 1472

    Topics: Cellulose; Chromatography, High Pressure Liquid; Eriobotrya; Isomerism; Limit of Detection; Oleanolic Acid; Plant Leaves; Solid Phase Extraction; Solvents; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2016
Phytochemical and biological evaluation of Salvia apiana.
    Natural product research, 2017, Volume: 31, Issue:17

    Topics: Abietanes; California; Drug Evaluation, Preclinical; Flavones; Magnetic Resonance Spectroscopy; Mexico; Oleanolic Acid; Phytochemicals; Plant Extracts; Plant Leaves; Plants, Medicinal; Receptor, Cannabinoid, CB1; Receptors, Opioid; Salvia; Triterpenes; Ursolic Acid

2017
Synthesis of novel oleanolic acid and ursolic acid in C-28 position derivatives as potential anticancer agents.
    Archives of pharmacal research, 2017, Volume: 40, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; MCF-7 Cells; Molecular Structure; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2017
Antimycobacterial, docking and molecular dynamic studies of pentacyclic triterpenes from Buddleja saligna leaves.
    Journal of biomolecular structure & dynamics, 2017, Volume: 35, Issue:12

    Topics: Antitubercular Agents; Buddleja; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacterium; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Plants, Medicinal; Triterpenes; Tuberculosis; Ursolic Acid

2017
Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors.
    Natural product research, 2017, Volume: 31, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Eriobotrya; Humans; Inhibitory Concentration 50; Molecular Structure; Oleanolic Acid; Phosphodiesterase 4 Inhibitors; Plant Leaves; Triterpenes; Ursolic Acid

2017
Anti-inflammatory activity of standardized dichloromethane extract of Salvia connivens on macrophages stimulated by LPS.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Flavonoids; Gas Chromatography-Mass Spectrometry; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Macrophages; Magnetic Resonance Spectroscopy; Male; Methylene Chloride; Mice; Oleanolic Acid; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Salvia; Solvents; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2017
Oleanolic acid and ursolic acid as potential inhibitors of human salivary α-amylase: insights from in vitro assays and in silico simulations.
    Journal of molecular modeling, 2017, Volume: 23, Issue:8

    Topics: Humans; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Oleanolic Acid; Protein Conformation; Salivary alpha-Amylases; Triterpenes; Ursolic Acid

2017
Bioactive Triterpenes from the Root of Salvia miltiorrhiza Bunge.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:9

    Topics: Drugs, Chinese Herbal; Ghrelin; HL-60 Cells; Humans; Molecular Structure; Oleanolic Acid; Plant Roots; Salvia miltiorrhiza; Triterpenes; Ursolic Acid

2017
Antimicrobial Mechanism of Oleanolic and Ursolic Acids on Streptococcus mutans UA159.
    Current microbiology, 2018, Volume: 75, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Betulinic Acid; Gene Expression Regulation, Bacterial; Oleanolic Acid; Pentacyclic Triterpenes; Streptococcus mutans; Triterpenes; Ursolic Acid

2018
Selective in vitro anti-melanoma activity of ursolic and oleanolic acids.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Melanoma; Mesenchymal Stem Cells; Oleanolic Acid; Triterpenes; Ursolic Acid

2018
In vivo anti-malarial activity and toxicity studies of triterpenic esters isolated form Keetia leucantha and crude extracts.
    Malaria journal, 2017, 10-10, Volume: 16, Issue:1

    Topics: Animals; Antimalarials; Esters; Female; Mice; Oleanolic Acid; Plant Extracts; Plasmodium berghei; Rubiaceae; Triterpenes; Ursolic Acid

2017
Inhibitory mechanism of two allosteric inhibitors, oleanolic acid and ursolic acid on α-glucosidase.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt B

    Topics: Acarbose; Allosteric Regulation; Allosteric Site; Circular Dichroism; Enzyme Activation; Glycoside Hydrolase Inhibitors; Kinetics; Molecular Dynamics Simulation; Oleanolic Acid; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Thermodynamics; Time Factors; Triterpenes; Ursolic Acid

2018
Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays.
    International journal of oncology, 2017, Volume: 51, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Humans; Melanoma; Neovascularization, Physiologic; Oleanolic Acid; Skin Neoplasms; Triterpenes; Ursolic Acid

2017
Betulinic, oleanolic and ursolic acids inhibit the enzymatic and biological effects induced by a P-I snake venom metalloproteinase.
    Chemico-biological interactions, 2018, Jan-05, Volume: 279

    Topics: Animals; Betulinic Acid; Bothrops; Crotalid Venoms; Edema; Hemorrhage; Metalloproteases; Mice; Molecular Structure; Muscular Diseases; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018
Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms.
    Molecules (Basel, Switzerland), 2017, Dec-16, Volume: 22, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Ericales; Female; Hydrolysis; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred C57BL; Microbial Sensitivity Tests; Oleanolic Acid; Plant Extracts; Plant Leaves; Staphylococcal Infections; Triterpenes; Ursolic Acid

2017
Study of isomeric pentacyclic triterpene acids in traditional Chinese medicine of Forsythiae Fructus and their binding constants with β-cyclodextrin by capillary electrophoresis.
    Electrophoresis, 2018, Volume: 39, Issue:7

    Topics: beta-Cyclodextrins; Betulinic Acid; Drugs, Chinese Herbal; Electrophoresis, Capillary; Forsythia; Fruit; Isomerism; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Thermodynamics; Triterpenes; Ursolic Acid

2018
Nanoemulsion Strategy for Ursolic and Oleanic Acids Isolates from
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:6

    Topics: Animals; Antioxidants; Apocynaceae; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Emulsions; Melanoma; Mice; Molecular Conformation; Nanoparticles; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2018
Markhacanasin C, cycloartane triterpenoid from the leaves of Markhamia stipulata var. canaense V.S. Dang.
    Natural product research, 2019, Volume: 33, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Bignoniaceae; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; MCF-7 Cells; Molecular Structure; Oleanolic Acid; Plant Extracts; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2019
α-Glucosidase enzyme inhibitory effects and ursolic and oleanolic acid contents of fourteen Anatolian Salvia species.
    Journal of pharmaceutical and biomedical analysis, 2018, Jun-05, Volume: 155

    Topics: Acetonitriles; alpha-Glucosidases; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Oleanolic Acid; Plant Extracts; Salvia; Triterpenes; Ursolic Acid

2018
Rapid and Sensitive Quantification of Ursolic Acid and Oleanolic Acid in Human Plasma Using Ultra-performance Liquid Chromatography-Mass Spectrometry.
    Journal of chromatographic science, 2018, Aug-01, Volume: 56, Issue:7

    Topics: Chromatography, High Pressure Liquid; Humans; Linear Models; Mass Spectrometry; Oleanolic Acid; Reproducibility of Results; Sensitivity and Specificity; Triterpenes; Ursolic Acid

2018
An Improved Scalable Synthesis of α- and β-Amyrin.
    Molecules (Basel, Switzerland), 2018, 06-27, Volume: 23, Issue:7

    Topics: Oleanolic Acid; Triterpenes; Ursolic Acid

2018
Bulk industrial fruit fibres. Characterization and prevalence of the original fruit metabolites.
    Food research international (Ottawa, Ont.), 2018, Volume: 111

    Topics: Carotenoids; Citrus; Citrus sinensis; Daucus carota; Food Industry; Fruit; Fruit and Vegetable Juices; Malus; Oleanolic Acid; Prunus persica; Pyrus; Sugars; Triterpenes; Ursolic Acid

2018
A Comprehensive Quality Evaluation Method Based on C
    Molecules (Basel, Switzerland), 2018, Aug-15, Volume: 23, Issue:8

    Topics: Antioxidants; Apigenin; Chromatography, High Pressure Liquid; Coumarins; Drugs, Chinese Herbal; Fruit; Glucosides; Glycosides; Isomerism; Ligustrum; Limit of Detection; Oleanolic Acid; Phenols; Pyrans; Reproducibility of Results; Triterpenes; Ursolic Acid

2018
Both Oleanolic Acid and a Mixture of Oleanolic and Ursolic Acids Mimic the Effects of Fructus ligustri lucidi on Bone Properties and Circulating 1,25-Dihydroxycholecalciferol in Ovariectomized Rats.
    The Journal of nutrition, 2018, 12-01, Volume: 148, Issue:12

    Topics: Animals; Bone and Bones; Bone Density; Calcitriol; Calcium; Female; Fruit; Ligustrum; Oleanolic Acid; Ovariectomy; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid

2018
Quantification of three triterpenic acids in dried rosemary using HPLC-fluorescence detection and 4-(4,5-diphenyl-1H-imidazole-2-yl)benzoyl chloride derivatization.
    Luminescence : the journal of biological and chemical luminescence, 2019, Volume: 34, Issue:1

    Topics: Benzoates; Betulinic Acid; Calibration; Chromatography, High Pressure Liquid; Fluorescence; Food Analysis; Imidazoles; Limit of Detection; Oleanolic Acid; Pentacyclic Triterpenes; Reproducibility of Results; Rosmarinus; Temperature; Triterpenes; Ursolic Acid

2019
Two New Triterpenes and Other Compounds from Mentha aquatica (Lamiaceae).
    Natural product communications, 2017, Volume: 12, Issue:4

    Topics: Mentha; Molecular Structure; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Triterpenes; Ursolic Acid

2017
Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential.
    Bioorganic chemistry, 2019, Volume: 85

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Molecular Docking Simulation; Oleanolic Acid; Protein Binding; Triterpenes; Ursolic Acid

2019
Development and Validation of an Analytical Method Based on HPLC-ELSD for the Simultaneous Determination of Rosmarinic Acid, Carnosol, Carnosic Acid, Oleanolic Acid and Ursolic Acid in Rosemary.
    Molecules (Basel, Switzerland), 2019, Jan-17, Volume: 24, Issue:2

    Topics: Abietanes; Calibration; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Limit of Detection; Oleanolic Acid; Reproducibility of Results; Rosmarinic Acid; Scattering, Radiation; Triterpenes; Ursolic Acid

2019
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:8

    Topics: Acetylcholinesterase; Achyranthes; Amyloid beta-Peptides; Animals; Antioxidants; Astrocytes; Behavior, Animal; Brain; Cognitive Dysfunction; Cytokines; Ecdysterone; Glutathione; Hippocampus; Inflammation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Microglia; Neuroprotective Agents; NF-kappa B; Oleanolic Acid; Peptide Fragments; Rats, Sprague-Dawley; Steroids; Triterpenes; Ursolic Acid

2019
Phytosterols and triterpenes from Morinda lucida Benth. exhibit binding tendency against class I HDAC and HDAC7 isoforms.
    Molecular biology reports, 2019, Volume: 46, Issue:2

    Topics: Cholesterol; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Docking Simulation; Morinda; Oleanolic Acid; Phytosterols; Plant Extracts; Plant Leaves; Protein Isoforms; Stigmasterol; Triterpenes; Ursolic Acid

2019
A new pentacyclic triterpenoid from the leaves of
    Natural product research, 2020, Volume: 34, Issue:23

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Drug Evaluation, Preclinical; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; RAW 264.7 Cells; Rhododendron; Triterpenes; Ursolic Acid

2020
New triterpenic acids produced in callus culture from fruit pulp of Acca sellowiana (O. Berg) Burret.
    Food research international (Ottawa, Ont.), 2019, Volume: 119

    Topics: Fruit; Gas Chromatography-Mass Spectrometry; Myrtaceae; Oleanolic Acid; Phlorhizin; Phytochemicals; Plant Extracts; Secondary Metabolism; Sitosterols; Triterpenes; Ursolic Acid

2019
Bioactive triterpenoids from
    Natural product research, 2020, Volume: 34, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Components, Aerial; RAW 264.7 Cells; Sambucus; Triterpenes; Ursolic Acid

2020
Tuscan Varieties of Sweet Cherry Are Rich Sources of Ursolic and Oleanolic Acid: Protein Modeling Coupled to Targeted Gene Expression and Metabolite Analyses.
    Molecules (Basel, Switzerland), 2019, Apr-22, Volume: 24, Issue:8

    Topics: Cytochrome P-450 Enzyme System; Fruit; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Models, Biological; Oleanolic Acid; Plant Proteins; Prunus avium; Triterpenes; Ursolic Acid

2019
LC-MS- and NMR-Guided Isolation of Monoterpene Dimers from Cultivated Thymus vulgaris Varico 3 Hybrid and Their Antityrosinase Activity.
    Planta medica, 2019, Volume: 85, Issue:11-12

    Topics: Flavones; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Monophenol Monooxygenase; Monoterpenes; Oleanolic Acid; Plant Extracts; Thymol; Thymus Plant; Triterpenes; Ursolic Acid

2019
Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement.
    Bioorganic chemistry, 2019, Volume: 90

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Humans; Liver Neoplasms; Malus; NF-kappa B; Olea; Oleanolic Acid; Plant Extracts; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2019
Two new terpenoids from the leaves of
    Natural product research, 2021, Volume: 35, Issue:7

    Topics: Callicarpa; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Oleanolic Acid; Plant Extracts; Plant Leaves; Proton Magnetic Resonance Spectroscopy; Terpenes; Triterpenes; Ursolic Acid

2021
Lotus japonicus Triterpenoid Profile and Characterization of the CYP716A51 and LjCYP93E1 Genes Involved in Their Biosynthesis In Planta.
    Plant & cell physiology, 2019, Nov-01, Volume: 60, Issue:11

    Topics: Gene Expression Regulation, Plant; Lotus; Oleanolic Acid; Plant Proteins; Triterpenes; Ursolic Acid

2019
Effect of harvesting year and elderberry cultivar on the chemical composition and potential bioactivity: A three-year study.
    Food chemistry, 2020, Jan-01, Volume: 302

    Topics: Agriculture; Anthocyanins; Antioxidants; Fruit; Oleanolic Acid; Phenols; Plant Extracts; Polyphenols; Portugal; Sambucus; Sambucus nigra; Species Specificity; Triterpenes; Ursolic Acid

2020
Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells.
    Molecules (Basel, Switzerland), 2019, Sep-23, Volume: 24, Issue:19

    Topics: A549 Cells; Humans; Mitophagy; Oleanolic Acid; Protein Kinases; Reactive Oxygen Species; Triterpenes; Ubiquitin-Protein Ligases; Ursolic Acid

2019
Antimicrobial properties of amine- and guanidine-functionalized derivatives of betulinic, ursolic and oleanolic acids: Synthesis and structure/activity evaluation.
    Steroids, 2020, Volume: 154

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Antifungal Agents; Betulinic Acid; Candida albicans; Cell Survival; Cryptococcus neoformans; Dose-Response Relationship, Drug; Escherichia coli; HEK293 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Pseudomonas aeruginosa; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2020
Identification and Quantitation of Ursolic and Oleanolic Acids in
    Molecules (Basel, Switzerland), 2019, Dec-03, Volume: 24, Issue:23

    Topics: Carbon-13 Magnetic Resonance Spectroscopy; Gas Chromatography-Mass Spectrometry; Ilex; Oleanolic Acid; Plant Extracts; Plant Leaves; Proton Magnetic Resonance Spectroscopy; Triterpenes; Ursolic Acid

2019
Hyaluronic acid-coated nanostructured lipid carriers for loading multiple traditional Chinese medicine components for liver cancer treatment.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Carriers; Drug Liberation; Female; Ginsenosides; Hyaluronic Acid; Lipids; Mice; Nanostructures; Neoplasms; Oleanolic Acid; Particle Size; Static Electricity; Tissue Distribution; Triterpenes; Ursolic Acid

2020
A green approach for the extraction and characterization of oridonin and ursolic and oleanolic acids from Rabdosia rubescens and its kinetic behavior.
    Food chemistry, 2020, Jul-30, Volume: 319

    Topics: Carbon Dioxide; Chemical Fractionation; Chromatography, High Pressure Liquid; Diterpenes, Kaurane; Green Chemistry Technology; Isodon; Kinetics; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Reproducibility of Results; Solvents; Tandem Mass Spectrometry; Triterpenes; Ultrasonics; Ursolic Acid

2020
Promotion of epithelial hyperplasia by interleukin-8-CXCR axis in human prostate.
    The Prostate, 2020, Volume: 80, Issue:12

    Topics: Cell Growth Processes; Cell Line; Cells, Cultured; Epithelium; Humans; Interleukin-8; Male; Oleanolic Acid; Prostate; Prostatic Hyperplasia; Receptors, CXCR; RNA, Messenger; Signal Transduction; Triterpenes; Ursolic Acid

2020
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
    Chemical & pharmaceutical bulletin, 2020, Volume: 68, Issue:10

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Proliferation; Cytochromes c; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Ursolic Acid

2020
Upregulation of UGT1A1 expression by ursolic acid and oleanolic acid via the inhibition of the PKC/NF-κB signaling pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 92

    Topics: Glucuronosyltransferase; NF-kappa B; Oleanolic Acid; Protein Kinase C; Signal Transduction; Triterpenes; Up-Regulation; Ursolic Acid

2021
Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice.
    Journal of natural medicines, 2022, Volume: 76, Issue:3

    Topics: Acetylcholinesterase; Animals; Donepezil; Mice; Ocimum sanctum; Oleanolic Acid; Olfactory Bulb; Plant Extracts; Triterpenes; Ursolic Acid; Vascular Endothelial Growth Factor A

2022
Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-cell leukemia MT-4 cells to promote surrounding cell growth.
    Medical oncology (Northwood, London, England), 2022, Jun-08, Volume: 39, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukocytes, Mononuclear; Mitochondria; Oleanolic Acid; Poly(ADP-ribose) Polymerase Inhibitors; Triterpenes; Ursolic Acid

2022
Ursolic acid inhibits the activation of smoothened-independent non-canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:9

    Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Hedgehog Proteins; Humans; Oleanolic Acid; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes; Ursolic Acid; Zinc Finger Protein GLI1

2022
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation.
    Journal of molecular medicine (Berlin, Germany), 2022, Volume: 100, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Diabetes Mellitus, Experimental; Eriobotrya; Hyperglycemia; Inflammation; Mice; Oleanolic Acid; Plant Extracts; Ursolic Acid

2022
Sorbus intermedia (EHRH.) PERS. fruits as a novel source of biologically active triterpenoids - Comparative studies of ursolic acid derivatives with cytotoxic potential.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Antineoplastic Agents; Fruit; Molecular Structure; Oleanolic Acid; Sorbus; Triterpenes; Ursolic Acid

2022
The Protective Effect of Ursolic Acid on Unilateral Ureteral Obstruction in Rats by Activating the Nrf2/HO-1 Antioxidant Signaling Pathway.
    Computational intelligence and neuroscience, 2022, Volume: 2022

    Topics: Animals; Antioxidants; Fibrosis; Heme Oxygenase (Decyclizing); Kidney Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Signal Transduction; Ureteral Obstruction; Ursolic Acid

2022
Acteoside and ursolic acid synergistically protects H
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Caspase 3; Glucosides; Hydrogen Peroxide; Network Pharmacology; Neuroprotective Agents; Oleanolic Acid; PC12 Cells; Polyphenols; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; TOR Serine-Threonine Kinases; Ursolic Acid

2022
Ursolic acid-piperazine-dithiocarbamate ruthenium(II) polypyridyl complexes induced necroptosis in MGC-803 cells.
    Metallomics : integrated biometal science, 2022, 10-11, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Clathrin; Coordination Complexes; Humans; Mice; Necroptosis; Oleanolic Acid; Piperazine; Propidium; Ruthenium; Ursolic Acid

2022
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
    Theranostics, 2022, Volume: 12, Issue:14

    Topics: Carcinogens; China; Colorectal Neoplasms; Humans; Immunologic Factors; Immunotherapy; Lentinan; Nanomedicine; Oleanolic Acid; Tumor Microenvironment; Ursolic Acid

2022
Ursolic and oleanolic acids in combination therapy inhibit migration of colon cancer cells through down-regulation of the uPA/uPAR-dependent MMPs pathway.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Cadherins; Colonic Neoplasms; Down-Regulation; Humans; Irinotecan; Matrix Metalloproteinase 2; Oleanolic Acid; Ursolic Acid

2022
Phytochemical study and immunomodulatory activity of Fraxinus excelsior L.
    The Journal of pharmacy and pharmacology, 2023, Jan-31, Volume: 75, Issue:1

    Topics: Fraxinus; Interleukin-12; Lipopolysaccharides; Oleanolic Acid; Phytochemicals; Plant Extracts; Tumor Necrosis Factor-alpha; Ursolic Acid

2023
Quality consistency evaluation of commercial Prunellae Spica by integrating determination of secondary metabolites and saccharides.
    Phytochemical analysis : PCA, 2023, Volume: 34, Issue:2

    Topics: Chromatography, High Pressure Liquid; Oleanolic Acid; Polysaccharides; Rosmarinic Acid; Sucrose; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2023
Targeted delivery of ursolic acid and oleanolic acid to lungs in the form of an inhaler for the management of tuberculosis: Pharmacokinetic and toxicity assessment.
    PloS one, 2022, Volume: 17, Issue:12

    Topics: Animals; Lung; Mycobacterium tuberculosis; Nebulizers and Vaporizers; Oleanolic Acid; Rats; Rats, Wistar; Triterpenes; Tuberculosis; Ursolic Acid

2022
Using network pharmacology and molecular docking verification to explore the mechanism of ursolic acid in the treatment of osteoporosis.
    Medicine, 2022, Dec-09, Volume: 101, Issue:49

    Topics: Caspase 3; Humans; Interleukin-6; Molecular Docking Simulation; Network Pharmacology; Oleanolic Acid; Osteoporosis; Ursolic Acid; Vascular Endothelial Growth Factor A

2022
Combinatorial metabolic engineering enables the efficient production of ursolic acid and oleanolic acid in Saccharomyces cerevisiae.
    Bioresource technology, 2023, Volume: 374

    Topics: Metabolic Engineering; Oleanolic Acid; Saccharomyces cerevisiae; Triterpenes; Ursolic Acid

2023
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice.
    European journal of pharmacology, 2023, Oct-05, Volume: 956

    Topics: Animals; Depression; Female; Hippocampus; Male; Maternal Deprivation; Mice; Neuroinflammatory Diseases; Oleanolic Acid; Synaptophysin; Ursolic Acid

2023
Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis.
    Journal of pharmaceutical and biomedical analysis, 2024, Jan-20, Volume: 238

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Iridoids; Oleanolic Acid; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2024