oleanolic acid has been researched along with transforming growth factor beta in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Birkey Reffey, S; Gribble, GW; Heiss, EH; Honda, T; Itoh, S; Miyazono, K; Place, AE; Risingsong, R; Roberts, AB; Sporn, MB; Suh, N; ten Dijke, P; Williams, CR | 1 |
| Gao, N; Kawashima, A; Miyata, N; Morimoto, S; Murakami, S; Saito, M; Saito, S; Sugawara, K; Yang, J; Yoshimura, H; Zhang, X | 1 |
| Buzoni-Gatel, D; Ely, KH; Kasper, LH; Luangsay, S; Minns, LA; Rachinel, N | 1 |
| Gong, Y; Li, P; Li, Y; Shimizu, F; Wang, B; Zu, N | 1 |
| Fenton, BM; Okunieff, P; Su, Y; Wang, W; Xiao, Z; Yang, S; Yi, Y; Yin, L; Zhang, L | 1 |
| Goodman, C; Ji, Y; Lee, HJ; Liby, K; Sporn, M; Suh, N; Uskokovic, M | 1 |
| Di Guglielmo, GM; Gribble, GW; Honda, T; Kulkarni, S; Pawson, T; Sporn, MB; To, C; Wrana, JL | 1 |
| Ferguson, HE; Garcia-Bates, TM; Huxlin, KR; Kulkarni, A; Lehmann, GM; Phipps, RP; Sime, PJ; Thatcher, TH | 1 |
| Feldon, SE; Hindman, HB; Huxlin, KR; Kulkarni, AA; Kuriyan, AE; Lehmann, GM; Phipps, RP; Sime, PJ; Woeller, CF | 1 |
| Chang, CD; Liao, MH; Lin, PY; Shih, WL; Wu, HY; Yu, FL | 1 |
| Distler, JH; Doniparthi, S; Hinchcliff, M; Komura, K; Lord, G; Tamaki, Z; Tomcik, M; Varga, J; Wang, W; Wei, J; Zhu, H | 1 |
| Hsiao, HM; Kottmann, RM; Kulkarni, AA; Morrissette, J; Olsen, KC; Phipps, RP; Sime, PJ; Thatcher, TH; Wright, TW | 1 |
| Aminzadeh, MA; Khazaeli, M; Meyer, CJ; Reisman, SA; Vaziri, ND; Yuan, J | 1 |
| Liby, KT; Lin, JJ; So, JY; Sporn, MB; Suh, N; Wahler, J | 1 |
| Bae, JS; Chung, J; Jung, B; Lee, T; Na, M; Zhou, W | 1 |
| Allaway, G; Bhattachayya, M; Biswal, SS; Jones, BM; Korman, B; Lord, G; Marangoni, RG; Tourtellotte, WG; Varga, J; Wei, J; Zhu, H | 1 |
| Logashenko, EB; Markov, AV; Zenkova, MA | 1 |
| Chen, J; Chen, JS; Gough, NR; He, AR; Latham, PS; Li, S; Lin, P; Malta, TM; Mishra, B; Mishra, L; Mitra, A; Nguyen, BN; Noushmehr, H; Obias, V; Rashid, A; Shin, JH; Song, S; Su, X; Wu, RC; Yao, Z | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Zhang, N; Zhou, M | 1 |
| He, L; Yang, W | 1 |
| Anton, MI; Ciocoiu, M; Costea, CF; Floria, M; Gosav, EM; Hurjui, LL; Rezus, C; Seritean Isac, PN; Tanase, DM; Tarniceriu, CC | 1 |
| Bahetibike, S; Huang, LT; Lu, YQ; Ma, HY; Mei, S; Qi, R; Wang, AH; Xiao, SL; Yang, RY; Yi, YL; Yu, ZW; Zhu, J; Zhu, SJ | 1 |
2 review(s) available for oleanolic acid and transforming growth factor beta
| Article | Year |
|---|---|
Modulation of Tumour-Related Signaling Pathways by Natural Pentacyclic Triterpenoids and their Semisynthetic Derivatives.
Topics: Antineoplastic Agents; Apoptosis; Humans; Neoplasms; NF-kappa B; Oleanolic Acid; Signal Transduction; Transforming Growth Factor beta; Triterpenes | 2017 |
Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives.
Topics: Antioxidants; Curcumin; Diabetic Nephropathies; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; Oxidative Stress; Quality of Life; Reactive Oxygen Species; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2022 |
20 other study(ies) available for oleanolic acid and transforming growth factor beta
| Article | Year |
|---|---|
Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
Topics: Acetyltransferases; Animals; Cell Cycle Proteins; DNA-Binding Proteins; Drug Synergism; Histone Acetyltransferases; Imidazoles; Leukemia, Promyelocytic, Acute; Lung; Macrophages; Mice; Mink; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleanolic Acid; p300-CBP Transcription Factors; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad7 Protein; Terpenes; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triterpenes | 2003 |
In vitro TGF-beta1 antagonistic activity of ursolic and oleanolic acids isolated from Clerodendranthus spicatus.
Topics: 3T3 Cells; Animals; China; Drugs, Chinese Herbal; Lamiaceae; Mice; Mice, Inbred BALB C; Oleanolic Acid; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid | 2003 |
A novel triterpenoid induces transforming growth factor beta production by intraepithelial lymphocytes to prevent ileitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Down-Regulation; Female; Ileitis; Injections, Intraperitoneal; Lymphocytes; Mice; Models, Animal; Oleanolic Acid; Signal Transduction; Toxoplasmosis; Transforming Growth Factor beta | 2004 |
Therapeutic mechanism of Saikosaponin-d in anti-Thy1 mAb 1-22-3-induced rat model of glomerulonephritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Blood Pressure; Blotting, Western; CD8-Positive T-Lymphocytes; Collagen Type I; Disease Progression; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Glomerulonephritis, Membranoproliferative; Isoantibodies; Kidney Glomerulus; Macrophages; Mesangial Cells; Oleanolic Acid; Proteinuria; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saponins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Protective effect of esculentoside A on radiation-induced dermatitis and fibrosis.
Topics: Animals; Cell Line, Tumor; Cytokines; Drugs, Chinese Herbal; Female; Fibroblasts; Fibrosis; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Oleanolic Acid; Radiodermatitis; Saponins; Skin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.
Topics: Bone Morphogenetic Protein 6; Bone Morphogenetic Proteins; Calcitriol; Carrier Proteins; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; HL-60 Cells; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Oleanolic Acid; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2006 |
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid-imidazolide alters transforming growth factor beta-dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex.
Topics: Active Transport, Cell Nucleus; Animals; Cell Movement; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cytoskeleton; Fibroblasts; Imidazoles; Microtubules; Models, Biological; Oleanolic Acid; Rats; Signal Transduction; Transforming Growth Factor beta | 2008 |
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
Topics: Acetylation; Actins; Base Sequence; Cell Differentiation; Cells, Cultured; DNA Primers; Fibroblasts; Humans; Ligands; Lung; Oleanolic Acid; p300-CBP Transcription Factors; PPAR gamma; Prostaglandin D2; Pulmonary Fibrosis; Rosiglitazone; Signal Transduction; Smad Proteins; Thiazolidinediones; Transcription Factor AP-1; Transforming Growth Factor beta | 2009 |
Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring.
Topics: Actins; Biomarkers; Blotting, Western; Cell Transdifferentiation; Cells, Cultured; Collagen Type I; Cornea; Fibroblasts; Fibronectins; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Ligands; Myofibroblasts; Oleanolic Acid; PPAR gamma; Prostaglandin D2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2012 |
Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavones; Fluorescent Antibody Technique; Glucose-6-Phosphate Isomerase; Humans; Immunoprecipitation; Liver Neoplasms; Luciferases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Mice; Mice, Nude; Neovascularization, Pathologic; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2013 |
A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.
Topics: Adipogenesis; Adult; Animals; Biopsy; Cells, Cultured; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fibroblasts; Fibrosis; Humans; Infant, Newborn; Mice; Mice, Inbred C57BL; Oleanolic Acid; Organ Culture Techniques; PPAR gamma; Proto-Oncogene Proteins c-akt; Scleroderma, Systemic; Signal Transduction; Skin; Transforming Growth Factor beta | 2014 |
The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.
Topics: Actins; Administration, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Fibronectins; Gene Expression; Humans; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Oleanolic Acid; Pneumonia; Pulmonary Fibrosis; Respiratory Function Tests; Transforming Growth Factor beta | 2013 |
The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease.
Topics: Animals; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Gene Expression Regulation; Inflammation; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Kidney; Male; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; RNA, Messenger; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta | 2014 |
A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Dose-Response Relationship, Drug; G2 Phase Cell Cycle Checkpoints; Hedgehog Proteins; Humans; Imidazoles; M Phase Cell Cycle Checkpoints; Neoplastic Stem Cells; Oleanolic Acid; Receptors, Notch; Signal Transduction; Transforming Growth Factor beta; Triple Negative Breast Neoplasms | 2014 |
Inhibitory effects of pentacyclic triterpenoids from Astilbe rivularis on TGFBIp-induced inflammatory responses in vitro and in vivo.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cell Adhesion; Cell Movement; Cell Survival; Extracellular Matrix Proteins; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Integrin beta Chains; Male; Mice; Mice, Inbred C57BL; Oleanolic Acid; Permeability; RNA, Small Interfering; Saxifragaceae; Sepsis; Transforming Growth Factor beta; Triterpenes; Vascular Cell Adhesion Molecule-1 | 2016 |
Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative.
Topics: Animals; Bleomycin; Cells, Cultured; Chalcones; Down-Regulation; Fibroblasts; Fibrosis; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oleanolic Acid; RNA, Messenger; Scleroderma, Systemic; Transforming Growth Factor beta | 2017 |
Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Exome Sequencing; Gene Deletion; Gene Expression Regulation; Gene Knockdown Techniques; Gene Silencing; Heterografts; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplastic Stem Cells; Oleanolic Acid; Phosphorylation; RNA, Small Interfering; Smad Proteins; Smad2 Protein; Smad3 Protein; Spectrin; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation | 2020 |
Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling.
Topics: Animals; Autophagy; Carbon Tetrachloride; Cells, Cultured; China; Fibrosis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Oleanolic Acid; Receptors, Estrogen; Receptors, G-Protein-Coupled; Saponins; Signal Transduction; Transforming Growth Factor beta | 2021 |
The protective effect of hederagenin on renal fibrosis by targeting muscarinic acetylcholine receptor.
Topics: Cell Line; Fibrosis; Humans; Kidney; Kidney Diseases; Oleanolic Acid; Pilocarpine; Receptors, Muscarinic; Transforming Growth Factor beta | 2022 |
Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway.
Topics: AMP-Activated Protein Kinases; Animals; Fibrosis; Mice; Molecular Docking Simulation; Oleanolic Acid; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2023 |