oleanolic acid has been researched along with petrosaspongiolide m in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alcaraz, MJ; Garcia-Pastor, P; Gomez-Paloma, L; Paya, M; Randazzo, A | 1 |
| Casapullo, A; Dal Piaz, F; Gomez-Paloma, L; Marino, G; Pucci, P; Randazzo, A; Riccio, R | 1 |
| Alcaraz, MJ; Gomez-Paloma, L; Payá, M; Posadas, I; Randazzo, A; Terencio, MC | 1 |
| Capasso, A; Casapullo, A; Gomez-Paloma, L; Randazzo, A | 1 |
| Casapullo, A; Gomez-Paloma, L; Monti, MC; Riccio, R | 2 |
| Delgado, R; Delporte, C; García, D; Garrido, G; González, D; Lemus, Y; Lodeiro, L; Núñez-Sellés, AJ; Quintero, G | 1 |
| Alcaraz, MJ; Busserolles, J; D'Auria, MV; Gomez-Paloma, L; Payá, M | 1 |
| Casapullo, A; Cavasotto, CN; Dal Piaz, F; Margarucci, L; Monti, MC; Riccio, R; Tosco, A; Ziemys, A | 1 |
| Casapullo, A; Margarucci, L; Monti, MC; Riccio, R; Tosco, A | 1 |
| Andrés, RM; Aquino, M; Bruno, I; De Simone, R; Guerrero, MD; Paya, M; Riccio, R; Terencio, MC | 1 |
| Casapullo, A; De Simone, R; Margarucci, L; Monti, MC; Riccio, R; Tosco, A | 1 |
| Bonfili, L; Casapullo, A; Eleuteri, AM; Margarucci, L; Monti, MC; Mozzicafreddo, M; Riccio, R | 1 |
13 other study(ies) available for oleanolic acid and petrosaspongiolide m
| Article | Year |
|---|---|
Effects of petrosaspongiolide M, a novel phospholipase A2 inhibitor, on acute and chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Survival; Dinoprostone; Edema; Enzyme Inhibitors; Exudates and Transudates; Humans; In Vitro Techniques; Inflammation; Leukocytes; Leukotriene B4; Male; Mice; Oleanolic Acid; Phospholipases A; Phospholipases A2; Porifera; Rats; Rats, Inbred Lew; Rats, Wistar; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Molecular basis of phospholipase A2 inhibition by petrosaspongiolide M.
Topics: Amino Acid Sequence; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bee Venoms; Binding Sites; Enzyme Inhibitors; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oleanolic Acid; Phospholipases A; Phospholipases A2; Terpenes | 2002 |
Inhibition of the NF-kappaB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M.
Topics: Animals; Anti-Inflammatory Agents; Biological Transport; Cell Movement; Cyclooxygenase 2; Cytokines; Dinoprostone; DNA; I-kappa B Proteins; Isoenzymes; Macrophages, Peritoneal; Mice; Models, Animal; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oleanolic Acid; Phosphorylation; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Petrosaspongiolide M reduces morphine withdrawal in vitro.
Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Oleanolic Acid; Phospholipases A; Substance Withdrawal Syndrome | 2003 |
Further insights on the structural aspects of PLA(2) inhibition by gamma-hydroxybutenolide-containing natural products: a comparative study on petrosaspongiolides M-R.
Topics: 4-Butyrolactone; Animals; Bee Venoms; Binding Sites; Biological Products; Chromatography, High Pressure Liquid; Computational Biology; Enzyme Inhibitors; Furans; Immunosuppressive Agents; Mass Spectrometry; Models, Molecular; Molecular Structure; Oleanolic Acid; Phospholipases A | 2004 |
In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG).
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cuba; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ear, External; Edema; Eicosanoids; Indomethacin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Mangifera; Mice; Oleanolic Acid; Peroxidase; Phospholipases A; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water; Xanthones | 2004 |
PLA2-mediated catalytic activation of its inhibitor 25-acetyl-petrosaspongiolide M: serendipitous identification of a new PLA2 suicide inhibitor.
Topics: Acetylation; Animals; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Circular Dichroism; Enzyme Inhibitors; Group II Phospholipases A2; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Ligands; Mass Spectrometry; Molecular Structure; Molecular Weight; Oleanolic Acid; Phospholipases A; Phospholipases A2; Porifera; Protein Conformation; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Temperature | 2004 |
Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M.
Topics: Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Colitis; Cyclooxygenase 2; Dysidea; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Inflammatory Bowel Diseases; Interleukin-1; Male; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleanolic Acid; Prostaglandin-Endoperoxide Synthases; Sesquiterpenes; Synaptotagmin I; Synaptotagmins; Trinitrobenzenesulfonic Acid | 2005 |
The binding mode of petrosaspongiolide M to the human group IIA phospholipase A(2): exploring the role of covalent and noncovalent interactions in the inhibition process.
Topics: Enzyme Inhibitors; Humans; Kinetics; Ligands; Models, Chemical; Molecular Conformation; Oleanolic Acid; Phospholipases A2; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance | 2009 |
Chemical proteomics discloses petrosapongiolide M, an antiinflammatory marine sesterterpene, as a proteasome inhibitor.
Topics: Anti-Inflammatory Agents; Cell Line; Databases, Protein; Enzyme Inhibitors; Humans; Oleanolic Acid; Proteasome Endopeptidase Complex; Protein Binding; Proteomics | 2010 |
Toward the discovery of new agents able to inhibit the expression of microsomal prostaglandin E synthase-1 enzyme as promising tools in drug development.
Topics: 4-Butyrolactone; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Drug Discovery; Gene Expression; Intramolecular Oxidoreductases; Macrophages; Mice; Microsomes; Oleanolic Acid; Prostaglandin-E Synthases; Thiophenes | 2010 |
Modulation of proteasome machinery by natural and synthetic analogues of the marine bioactive compound petrosaspongiolide M.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Fluorometry; Humans; Oleanolic Acid; Phospholipases A; Porifera; Proteasome Inhibitors; Structure-Activity Relationship; U937 Cells | 2012 |
Mechanistic insights on petrosaspongiolide M inhibitory effects on immunoproteasome and autophagy.
Topics: Autophagy; Binding Sites; Cell Line, Tumor; Humans; Kinetics; Lymphocytes; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Oleanolic Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Subunits; Proteolysis; Spectrometry, Mass, Electrospray Ionization | 2014 |