Page last updated: 2024-08-21

oleanolic acid and metallothionein

oleanolic acid has been researched along with metallothionein in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jia, XS; Klaassen, CD; Liu, J; Liu, YP; Mao, Q1
Choudhuri, S; Klaassen, CD; Kreppel, H; Liu, J; Liu, Y1
Andrews, GK; Choudhuri, S; Klaassen, CD; Kreppel, H; Liu, J; Liu, Y1
Iszard, MB; Klaassen, CD; Liu, J1
Baines, D; Daston, GP; Duffy, JY; Keen, CL; Overmann, GJ1
Hartley, DP; Liu, J; Liu, Y1
Klaassen, CD; Liu, J; Oguro, T; Yoshida, T1
Liu, J; Liu, YP1
Choi, YM; Jeong, HG; Jeong, TC; Kim, DH; Kim, JY; Lee, ES; Lee, KJ1
Choi, CY; Jeong, HG; Kim, JY1
Liu, J; Lu, YF; Pi, J; Wu, Q1

Other Studies

11 other study(ies) available for oleanolic acid and metallothionein

ArticleYear
Protective effects of fulvotomentosides on cadmium-induced hepatotoxicity.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Liver; Male; Metallothionein; Mice; Oleanolic Acid; Saponins; Tissue Distribution

1992
Oleanolic acid protects against cadmium hepatotoxicity by inducing metallothionein.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1

    Topics: Alanine Transaminase; Animals; Blotting, Northern; Cadmium; Chemical and Drug Induced Liver Injury; Cytosol; Dose-Response Relationship, Drug; Isomerism; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Metallothionein; Mice; Mice, Inbred Strains; Oleanolic Acid; Organ Size; RNA Probes; RNA, Messenger; Subcellular Fractions; Tissue Distribution

1993
Induction of metallothionein by alpha-hederin.
    Toxicology and applied pharmacology, 1993, Volume: 121, Issue:1

    Topics: Alanine Transaminase; Animals; Binding Sites; Blotting, Northern; Cadmium; Cadmium Chloride; Chlorides; Cytosol; Dose-Response Relationship, Drug; L-Iditol 2-Dehydrogenase; Liver; Male; Metallothionein; Mice; Microsomes, Liver; Mitochondria, Liver; Oleanolic Acid; RNA, Messenger; Saponins; Tissue Distribution

1993
Effect of several metallothionein inducers on oxidative stress defense mechanisms in rats.
    Toxicology, 1995, Dec-15, Volume: 104, Issue:1-3

    Topics: Analysis of Variance; Animals; Cadmium; Cadmium Chloride; Carcinogens; Catalase; Chlorides; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Dihydrolipoamide Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Lipopolysaccharides; Liver; Male; Metallothionein; Oleanolic Acid; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Selenium; Superoxide Dismutase; Testosterone; Zinc Compounds

1995
Repeated administration of alpha-hederin results in alterations in maternal zinc status and adverse developmental outcome in the rat.
    Teratology, 1997, Volume: 56, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Embryonic and Fetal Development; Female; Maternal-Fetal Exchange; Metallothionein; Oleanolic Acid; Pregnancy; Pregnancy Outcome; Rats; Rats, Sprague-Dawley; Saponins; Zinc; Zinc Radioisotopes

1997
Protection against carbon tetrachloride hepatotoxicity by oleanolic acid is not mediated through metallothionein.
    Toxicology letters, 1998, Mar-31, Volume: 95, Issue:2

    Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Metallothionein; Mice; Mice, Knockout; Oleanolic Acid; Rats; Rats, Sprague-Dawley

1998
Inhibitory effect of oleanolic acid on 12-O-tetradecanoylphorbol-13-acetate-induced gene expression in mouse skin.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 45, Issue:1

    Topics: Animals; Carcinogens; Female; Gene Expression; Metallothionein; Mice; Oleanolic Acid; Ornithine Decarboxylase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin; Tetradecanoylphorbol Acetate

1998
Effect of alpha-hederin on hepatic detoxifying systems in mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:1

    Topics: Animals; Antioxidants; Catalase; Copper; Drugs, Chinese Herbal; Glutathione; Liver; Male; Metallothionein; Mice; Oleanolic Acid; Saponins; Zinc

1997
Cytokine-mediated induction of metallothionein in Hepa-1c1c7 cells by oleanolic acid.
    Biochemical and biophysical research communications, 2004, Dec-17, Volume: 325, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Interleukin-6; Liver Neoplasms; Macrophages; Metallothionein; Mice; Oleanolic Acid; Tumor Necrosis Factor-alpha; Up-Regulation

2004
Involvement of cytokines in the hepatic metallothionein expression by alpha-hederin.
    Planta medica, 2005, Volume: 71, Issue:8

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Interleukin-6; Macrophages; Metallothionein; Mice; Oleanolic Acid; Phytotherapy; Plants, Medicinal; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saponins; Tumor Necrosis Factor-alpha

2005
New insights into generalized hepatoprotective effects of oleanolic acid: key roles of metallothionein and Nrf2 induction.
    Biochemical pharmacology, 2008, Oct-01, Volume: 76, Issue:7

    Topics: Animals; DNA, Complementary; Gene Expression Profiling; Liver; Male; Metallothionein; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Oligonucleotide Array Sequence Analysis; Protective Agents; Rats; Rats, Sprague-Dawley; Zinc

2008