Page last updated: 2024-08-21

oleanolic acid and malondialdehyde

oleanolic acid has been researched along with malondialdehyde in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (21.43)29.6817
2010's15 (53.57)24.3611
2020's7 (25.00)2.80

Authors

AuthorsStudies
Choi, J; Jung, GO; Lee, KT; Park, HJ; Park, KY1
Chen, XL; Hu, HT; Liu, Y; Qian, YH; Ren, HM; Xu, JH1
Chen, Y; Liu, J; Xu, H; Yang, X; Zhao, X1
Chen, Z; Lou, Y; Wang, C1
Chen, YW; Guo, JZ; He, Y; Hu, ZF; Li, KM; Li, P; Pan, L; Xiao, C; Xiong, JP1
Tsai, SJ; Yin, MC1
Chen, W; Hong, Z; Hu, J; Li, T; Wu, Z; Zhao, J; Zhou, J1
Huang, W; Sun, R1
Chakraborty, S; Chandran, P; Das, N1
Chang, YS; Ho, YL; Lai, SC; Liao, CR; Peng, WH1
Huang, XT; Li, N; Li, YY; Liu, CH; Mi, SQ; Wang, NS; Zheng, X1
Chang, YS; Choi, BS; Chung, S; Hong, YA; Kim, EN; Kim, MY; Koh, ES; Lim, JH; Park, CW; Shin, SJ1
Cao, RF; Chen, JW; Cong, X; Cui, K; Gao, SS; Guo, XT; Jiang, ZL; Tian, WR; Zhang, BZ; Zhao, Y1
Cai, J; Cao, W; Chen, J; Chu, X; Deng, H; Li, X; Liu, Z; Mao, L; Sun, S; Zha, L1
Madlala, HP; Mubagwa, K; Musabayane, CT; Van Heerden, FR1
Guo, C; Li, F; Meng, Z; Shen, J; Yang, X1
Jiang, T; Li, G; Peng, W; Sun, W; Yu, R; Yu, Z1
Cao, FY; Deng, HJ; Peng, HB; Tang, JD; Wang, JH; Wang, RX; Wang, YH1
Chen, Y; Li, Y; Lin, L; Que, R; Shen, Y; Yan, N1
Cheng, YD; Lan, WC; Lee, SC; Lin, LW; Tsai, FH; Wu, CR1
Chen, X; Peng, X; Rao, X; Zheng, C; Zhu, Y1
Ding, D; Gai, C; Li, W; Li, Z; Lv, S; Wang, Y; Yu, M; Zhang, W; Zheng, J1
Jiang, P; Li, Y; Nie, J1
Baldini, F; Khalil, M; Miraglia, N; Putignano, P; Vergani, L; Voci, A1
Hou, X; Jiang, X; Liu, H; Ping, Y; Song, C; Song, J; Zhang, F; Zhang, Z; Zhi, L1
Ke, H; Li, W; Li, X; Liu, Y; Ouyang, C; Zhou, J1
Du, J; Huang, X; Li, B; Li, L; Li, Y; Liu, J; Song, D1
Chen, T; Chen, Y; Li, Y; Shen, X; Tao, L; Xu, Y; Yang, H; Zhang, E1

Other Studies

28 other study(ies) available for oleanolic acid and malondialdehyde

ArticleYear
Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana.
    Archives of pharmacal research, 2002, Volume: 25, Issue:3

    Topics: Animals; Antimutagenic Agents; Antioxidants; Carbohydrate Sequence; Flowers; In Vitro Techniques; Isoflavones; Lipid Peroxidation; Liver; Male; Malondialdehyde; Molecular Sequence Data; Mutagens; Oleanolic Acid; Pueraria; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Saponins; Subcellular Fractions

2002
The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35.
    Anatomical science international, 2002, Volume: 77, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Hydro-Lyases; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Peptide Fragments; Rats; Saponins; Tetrazolium Salts; Thiazoles

2002
Oleanolic acid nanosuspensions: preparation, in-vitro characterization and enhanced hepatoprotective effect.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:2

    Topics: Administration, Oral; Alanine Transaminase; Animals; Calorimetry, Differential Scanning; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; China; Dosage Forms; Drug Evaluation, Preclinical; Hepatocytes; Injections, Subcutaneous; Liver Diseases; Malondialdehyde; Medicine, Chinese Traditional; Mice; Nanostructures; Oleanolic Acid; Particle Size; Solubility; Suspensions; Triterpenes; X-Ray Diffraction

2005
[Experimental study of Oleanolic acid liquid acting on climacteric rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:7

    Topics: Adrenal Cortex; Animals; Biomarkers; Climacteric; Estradiol; Female; Glutathione Peroxidase; Ligustrum; Malondialdehyde; Oleanolic Acid; Ovary; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2005
[Experimental study of saikosaponin-D (SSd) on lipid peroxidation of hepatic fibrosis on rat].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:8

    Topics: Animals; Aspartate Aminotransferases; Collagen Type IV; Dimethylnitrosamine; Hyaluronic Acid; Laminin; Lipid Peroxidation; Liver Cirrhosis; Malondialdehyde; Oleanolic Acid; Rats; Saponins; Superoxide Dismutase

2008
Antioxidative and anti-inflammatory protection of oleanolic acid and ursolic acid in PC12 cells.
    Journal of food science, 2008, Volume: 73, Issue:7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Cell Death; Glutathione Peroxidase; Hydrogen Peroxide; Interleukin-6; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Oleanolic Acid; Oxidative Stress; PC12 Cells; Rats; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2008
Hepatoprotective effects of Rubus aleaefolius Poir. and identification of its active constituents.
    Journal of ethnopharmacology, 2010, May-27, Volume: 129, Issue:2

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Rosaceae; Sitosterols; Superoxide Dismutase; Triterpenes

2010
[Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:13

    Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Liver; Male; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Saponins; Superoxide Dismutase

2010
Potent spermicidal effect of oleanolic acid 3-beta-D-glucuronide, an active principle isolated from the plant Sesbania sesban Merrill.
    Contraception, 2011, Volume: 83, Issue:2

    Topics: Animals; Cell Membrane; Contraception; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fertilization; Glucuronates; Lactobacillus acidophilus; Male; Malondialdehyde; Microbial Sensitivity Tests; Mutagenicity Tests; Oleanolic Acid; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Sesbania; Sperm Motility; Spermatocidal Agents; Spermatozoa

2011
Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice.
    The American journal of Chinese medicine, 2012, Volume: 40, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Elaeagnaceae; Flavonoids; Flavonols; Formaldehyde; Inflammation; Inflammation Mediators; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oleanolic Acid; Pain; Phytotherapy; Plant Extracts; Polyphenols; Triterpenes; Ursolic Acid

2012
[The anti-portal hypertension effect of oleanolic acid in CCl4-induced cirrhosis rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:6

    Topics: Animals; Body Weight; Carbon Tetrachloride; Disease Models, Animal; Hypertension, Portal; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oleanolic Acid; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley

2012
Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling.
    Journal of translational medicine, 2014, Feb-21, Volume: 12

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Apoptosis; Biomarkers; Cell Nucleus; Cyclosporine; Cytoskeletal Proteins; Fibrosis; Heme Oxygenase-1; Kelch-Like ECH-Associated Protein 1; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2014
Saikosaponin-D attenuates heat stress-induced oxidative damage in LLC-PK1 cells by increasing the expression of anti-oxidant enzymes and HSP72.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:5

    Topics: Animals; Bupleurum; Catalase; Dose-Response Relationship, Drug; Glutathione Peroxidase; Heat-Shock Response; Hot Temperature; HSP72 Heat-Shock Proteins; LLC-PK1 Cells; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Saponins; Superoxide Dismutase; Swine

2014
Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Cell Line; Chromones; Cyclooxygenase 2; Dinoprostone; Glycine max; I-kappa B Kinase; Inflammation; Lipopolysaccharides; Macrophages; Malondialdehyde; Mice; Morpholines; Nitriles; Oleanolic Acid; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Saponins; Signal Transduction; Sulfones; Superoxide Dismutase; Transcription Factor RelA

2014
Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Arginine Vasopressin; Blood Pressure; Glutathione Peroxidase; Hypertension; Kidney Tubules, Proximal; Lithium Chloride; Male; Malondialdehyde; Oleanolic Acid; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Sodium; Sodium Chloride; Superoxide Dismutase; Syzygium

2015
Neuroprotective effects of polygalacic acid on scopolamine-induced memory deficits in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Feb-15, Volume: 23, Issue:2

    Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Glutathione; Hippocampus; Interleukins; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Mice; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Polygala; Random Allocation; Saponins; Scopolamine; Superoxide Dismutase

2016
Pharmacokinetics in Vitro and in Vivo of Two Novel Prodrugs of Oleanolic Acid in Rats and Its Hepatoprotective Effects against Liver Injury Induced by CCl4.
    Molecular pharmaceutics, 2016, 05-02, Volume: 13, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Liver; Male; Malondialdehyde; Oleanolic Acid; Prodrugs; Protective Agents; Rats; Rats, Wistar; Tissue Distribution

2016
Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF‑κB pathway in silicotic rats.
    Molecular medicine reports, 2017, Volume: 15, Issue:5

    Topics: Animals; Collagen; Cytokines; Fibrosis; Glutathione Peroxidase; Lung; Male; Malondialdehyde; NF-kappa B; Oleanolic Acid; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Silicosis; Superoxide Dismutase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2017
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line.
    Molecular medicine reports, 2018, Volume: 17, Issue:6

    Topics: Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytokines; Inflammasomes; Inflammation Mediators; Liver; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Oxidative Stress; Saponins

2018
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:8

    Topics: Acetylcholinesterase; Achyranthes; Amyloid beta-Peptides; Animals; Antioxidants; Astrocytes; Behavior, Animal; Brain; Cognitive Dysfunction; Cytokines; Ecdysterone; Glutathione; Hippocampus; Inflammation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Microglia; Neuroprotective Agents; NF-kappa B; Oleanolic Acid; Peptide Fragments; Rats, Sprague-Dawley; Steroids; Triterpenes; Ursolic Acid

2019
Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα.
    International immunopharmacology, 2019, Volume: 72

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Galactosamine; Hep G2 Cells; Humans; Interleukin-1beta; Lipopolysaccharides; Liver; Liver X Receptors; Malondialdehyde; Mice, Inbred C57BL; Oleanolic Acid; Peroxidase; Saponins; Tumor Necrosis Factor-alpha

2019
Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer.
    Journal of cellular physiology, 2020, Volume: 235, Issue:4

    Topics: Acetaminophen; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Synergism; Ferroptosis; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lipid Peroxides; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Piperazines; Signal Transduction; Xenograft Model Antitumor Assays

2020
Oleanolic acid mitigates interleukin-1β-induced chondrocyte dysfunction by regulating miR-148-3p-modulated FGF2 expression.
    The journal of gene medicine, 2020, Volume: 22, Issue:5

    Topics: 3' Untranslated Regions; 8-Hydroxy-2'-Deoxyguanosine; Algorithms; Apoptosis; Cell Proliferation; Cells, Cultured; Chondrocytes; Computational Biology; Fibroblast Growth Factor 2; Humans; Interleukin-1beta; Malondialdehyde; Microarray Analysis; MicroRNAs; Oleanolic Acid; Real-Time Polymerase Chain Reaction; Signal Transduction

2020
New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells.
    Molecules (Basel, Switzerland), 2020, Sep-15, Volume: 25, Issue:18

    Topics: Animals; Cell Line, Tumor; Cell Movement; Endothelial Cells; Hepatocytes; Malondialdehyde; Nitric Oxide; Non-alcoholic Fatty Liver Disease; Oleanolic Acid; Oxidative Stress; Palmitic Acid; Rats; Reactive Oxygen Species; S-Adenosylmethionine

2020
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
    Brain research bulletin, 2021, Volume: 173

    Topics: Animals; Antidepressive Agents; Antioxidant Response Elements; Cell Death; Depressive Disorder; Disease Models, Animal; Hippocampus; Imidazoles; Lipid Peroxidation; Malondialdehyde; Neurons; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Signal Transduction; Stroke

2021
[Protective effect of oleanolic acid on L02 hepatocyte injury induced by HgCl_2].
    Wei sheng yan jiu = Journal of hygiene research, 2021, Volume: 50, Issue:5

    Topics: Apoptosis; Hepatocytes; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species

2021
Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K.
    Neurotoxicity research, 2022, Volume: 40, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Glutamic Acid; Heme Oxygenase-1; Humans; Malondialdehyde; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Saponins; Signal Transduction

2022
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
    Molecules (Basel, Switzerland), 2022, Sep-24, Volume: 27, Issue:19

    Topics: Animals; Benzyl Alcohols; Cognitive Dysfunction; Cyclooxygenase 2; Dementia, Vascular; Ferroptosis; Glucosides; Glutathione; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; NF-E2-Related Factor 2; Oleanolic Acid; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Signal Transduction

2022