Page last updated: 2024-08-21

oleanolic acid and glycyrrhizic acid

oleanolic acid has been researched along with glycyrrhizic acid in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's7 (25.00)18.2507
2000's9 (32.14)29.6817
2010's7 (25.00)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Ahn, JS; Bae, K; Cui, L; Kim, BY; Min, BS; Na, M; Oh, WK; Yoo, JK1
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Dong, YS; Sun, WL; Wen, C; Xing, Y; Xiu, ZL; Yu, XX; Zhang, BW1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Chen, FK; Guo, YZ; Kano, Y; Meng, XS1
Kobayashi, M; Koike, M; Miyashiro, E; Sumiyama, K1
Amagaya, S; Iwama, H; Ogihara, Y1
Wang, JT1
Han, DW; Li, CM; Ma, XH; Yin, L; Zhao, MQ; Zhao, YC1
Li, Q; Murakamio, T; Okita, K; Takahashi, M1
Hattori, T; Isobe, K; Iwamoto, T; Kato, M; Lwin, T; Nagase, F; Nakashima, I; Pu, MY; Yanagita, N; Zhang, YH1
Ishihara, K; Ito, K; Kosuge, E; Kuriyama, M; Nakamura, T1
Kashimoto, T; Kudo, K; Tachikawa, E; Takahashi, E1
Hiai, S; Nagasawa, T; Zhang, ZQ; Zhou, QL1
Ebizuka, Y; Hayashi, H; Hiraoka, N; Huang, P; Ikeshiro, Y; Inoue, K; Kirakosyan, A; Kushiro, T; Shibuya, M1
Hirakawa, T; Kinjo, J; Nagao, T; Nohara, T; Okabe, H; Okawa, M; Tsuchihashi, R1
Kuttan, G; Raphael, TJ1
Ikeda, T; Kinjo, J; Nohara, T; Okawa, M; Tsuchihashi, R; Uyeda, M; Yokomizo, K1
Chen, T; Dong, Y; Sun, Y; Xu, Q; Zhang, L1
Chang, YS; Chen, JC; Ho, TY; Hsiang, CY; Li, CC; Wu, SL1
Daines, AM; Greatrex, BW; Hayman, CM; Hook, SM; McBurney, WT; Rades, T; Rendle, PM; Sims, IM1
Gotoh, T; Hokari, M; Hori, K; Sugiyama, T; Takahashi, S1
Shoyama, Y; Tuvshintogtokh, I; Uto, T1
Akashi, T; Aoki, T; Fukushima, EO; Mizutani, M; Muranaka, T; Ohnishi, T; Ohyama, K; Saito, K; Sawai, S; Seki, H; Sudo, H1
Tsao, SM; Yin, MC1
Chen, R; Huang, C; Li, B; Li, J; Liu, Y; Ma, T; Meng, X; Shen, C; Wu, M; Xu, Q1
Hanashima, S; Malabed, R; Murata, M; Sakurai, K1
Aalami, A; Shirazi, Z; Sohani, MM; Tohidfar, M1

Trials

1 trial(s) available for oleanolic acid and glycyrrhizic acid

ArticleYear
[A double-blind study of strong neominophagen-C in treating chronic hepatitis].
    Zhonghua nei ke za zhi, 1984, Volume: 23, Issue:1

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Cysteine; Double-Blind Method; Drug Combinations; Female; Glycine; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Hepatitis; Humans; Male; Oleanolic Acid; Plants, Medicinal

1984

Other Studies

27 other study(ies) available for oleanolic acid and glycyrrhizic acid

ArticleYear
Protein tyrosine phosphatase 1B inhibitory activity of triterpenes isolated from Astilbe koreana.
    Bioorganic & medicinal chemistry letters, 2006, Jun-15, Volume: 16, Issue:12

    Topics: Enzyme Inhibitors; Humans; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Saxifragaceae; Triterpenes

2006
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose.
    Bioorganic & medicinal chemistry letters, 2017, 11-15, Volume: 27, Issue:22

    Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Drug Synergism; Inhibitory Concentration 50; Kinetics; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes

2017
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
[The identification and determination of marker substances in xiaoyao wan by three dimensional HPLC].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:11

    Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Monoterpenes; Oleanolic Acid; Sapogenins; Saponins

1992
Combination therapy with transfer factor and high dose stronger neo-minophagen C in chronic hepatitis B in children (HBe Ag positive).
    Acta paediatrica Japonica : Overseas edition, 1991, Volume: 33, Issue:3

    Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Combined Modality Therapy; Cysteine; Drug Combinations; Female; Glycine; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis B; Hepatitis B e Antigens; Hepatitis, Chronic; Humans; Infant; Injections, Intravenous; Male; Oleanolic Acid; Solutions; Time Factors; Transfer Factor

1991
Studies of the combined use of steroid and Shosaikoto, one of the Kampohozai (Chinese traditional medicine), on pituitary adrenocortical axis function and immune responses.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:2

    Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hemagglutinins; Hemolytic Plaque Technique; Immunity; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Organ Size; Pituitary-Adrenal System; Plant Extracts; Plants, Medicinal; Prednisolone; Rats; Rats, Inbred Strains; Rosette Formation; Sapogenins; Saponins; Spleen

1986
[Preventive and therapeutic actions of glycyrrhizin, glycyrrhetic acid and crude saikosides on experimental liver cirrhosis in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:5

    Topics: Animals; Collagen; Fatty Liver; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis; Liver Cirrhosis; Male; Oleanolic Acid; Rats; Sapogenins; Saponins

1983
Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1993, Volume: 2, Issue:2

    Topics: alpha-Fetoproteins; Antineoplastic Agents; Astringents; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Division; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Liver Neoplasms; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins; Tumor Cells, Cultured

1993
Characterization of the immunoregulatory action of saikosaponin-d.
    Cellular immunology, 1994, Volume: 159, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Blotting, Northern; Cell Division; Fluorescent Antibody Technique; Genes, fos; Glycyrrhetinic Acid; Glycyrrhizic Acid; Immunosuppressive Agents; Interleukin-2; Mice; Mice, Inbred C57BL; Oleanolic Acid; Phosphorylation; Receptors, Interleukin-2; Sapogenins; Saponins; Signal Transduction; Spleen; T-Lymphocytes; Tyrosine; Up-Regulation

1994
Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils.
    Annals of the New York Academy of Sciences, 1993, Jun-23, Volume: 685

    Topics: Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Immunosuppressive Agents; Medicine, Kampo; Neutrophils; Oleanolic Acid; Platelet Activating Factor; Sapogenins; Saponins

1993
Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells.
    European journal of pharmacology, 1998, Jan-12, Volume: 341, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cardiac Glycosides; Catecholamines; Cattle; Central Nervous System Agents; Chromaffin Cells; Dose-Response Relationship, Drug; Ginsenosides; Glycyrrhizic Acid; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins

1998
[The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:7

    Topics: Cell-Free System; Glycyrrhizic Acid; Humans; Oleanolic Acid; Sapogenins; Saponins; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship

1996
Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:8

    Topics: Amino Acid Sequence; Blotting, Northern; Blotting, Southern; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Glycyrrhiza; Glycyrrhizic Acid; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; RNA, Messenger; Saccharomyces cerevisiae; Saponins

2001
Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:9

    Topics: Carbohydrate Sequence; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Glucuronides; Glycyrrhizic Acid; Humans; Liver; Molecular Sequence Data; Oleanolic Acid; Saponins; tert-Butylhydroperoxide

2003
Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, Volume: 10, Issue:6-7

    Topics: Animals; Benzoxepins; Bone Marrow Cells; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Hypersensitivity, Delayed; Immune System; Injections, Intraperitoneal; Leukocyte Count; Limonins; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; Phytotherapy; Sheep; Spleen; Triterpenes; Ursolic Acid

2003
Anti-herpes virus type 1 activity of oleanane-type triterpenoids.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:9

    Topics: Animals; Antiviral Agents; Carbohydrate Sequence; Chlorocebus aethiops; Glycyrrhetinic Acid; Glycyrrhizic Acid; Herpesvirus 1, Human; Humans; Molecular Sequence Data; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Vero Cells; Viral Plaque Assay

2005
Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:9

    Topics: Animals; Benzoates; Bridged-Ring Compounds; Cell Adhesion; Cells, Cultured; Concanavalin A; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Flavanones; Glucosides; Glycyrrhizic Acid; Immunosuppressive Agents; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Monoterpenes; Nitric Oxide; Oleanolic Acid; Picryl Chloride; RNA, Messenger; Saponins; Spleen

2006
Identification of Escherichia coli enterotoxin inhibitors from traditional medicinal herbs by in silico, in vitro, and in vivo analyses.
    Journal of ethnopharmacology, 2009, Jan-30, Volume: 121, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Diarrhea; Enterotoxigenic Escherichia coli; Enterotoxins; Escherichia coli Infections; Female; Gangliosides; Glycyrrhiza uralensis; Glycyrrhizic Acid; In Vitro Techniques; Mice; Mice, Inbred BALB C; Oleanolic Acid; Phytotherapy; Plant Extracts; Virulence Factors

2009
Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Animals; Cholesterol; Dendritic Cells; Glycosylation; Glycyrrhizic Acid; Hematopoiesis; Hematopoietic Stem Cells; ISCOMs; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Nanostructures; Oleanolic Acid; Phospholipids; Saponins

2009
Inhibition of human renin activity by saponins.
    Biomedical research (Tokyo, Japan), 2010, Volume: 31, Issue:2

    Topics: Fruit; Glycine max; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Oleanolic Acid; Renin; Saponins

2010
Preparation of knockout extract for determination of really active compound using MAb.
    Current drug discovery technologies, 2011, Volume: 8, Issue:1

    Topics: Antibodies, Monoclonal; Chromatography, Affinity; Complex Mixtures; Ginsenosides; Glycyrrhizic Acid; Immunoassay; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Panax; Plant Extracts; Rhizome; Saponins

2011
Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin.
    The Plant cell, 2011, Volume: 23, Issue:11

    Topics: Cytochrome P-450 Enzyme System; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Medicago truncatula; Molecular Sequence Data; Oleanolic Acid; Triterpenes; Yeasts

2011
Antioxidative and antiinflammatory activities of asiatic acid, glycyrrhizic acid, and oleanolic acid in human bronchial epithelial cells.
    Journal of agricultural and food chemistry, 2015, Apr-01, Volume: 63, Issue:12

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Bronchi; Cell Line; Epithelial Cells; Glycyrrhizic Acid; Humans; Hydrogen Peroxide; Oleanolic Acid; Pentacyclic Triterpenes; Reactive Oxygen Species

2015
The permeability characteristics and interaction of main components from Si-Ni-San in a MDCK epithelial cell monolayer model.
    Xenobiotica; the fate of foreign compounds in biological systems, 2021, Volume: 51, Issue:2

    Topics: Animals; Biological Transport; Dogs; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Humans; Madin Darby Canine Kidney Cells; Models, Biological; Monoterpenes; Oleanolic Acid; Permeability; Saponins; Verapamil

2021
Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins.
    Biochimica et biophysica acta. Biomembranes, 2017, Volume: 1859, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Biological Transport; Cholestenones; Cholesterol; Digitonin; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Fluoresceins; Glycyrrhizic Acid; Hemolysis; Humans; Membrane Lipids; Oleanolic Acid; Ornithogalum; Phosphatidylcholines; Saponins; Unilamellar Liposomes

2017
Metabolic Engineering of Glycyrrhizin Pathway by Over-Expression of Beta-amyrin 11-Oxidase in Transgenic Roots of Glycyrrhiza glabra.
    Molecular biotechnology, 2018, Volume: 60, Issue:6

    Topics: Agrobacterium; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Gene Transfer Techniques; Glycyrrhiza; Glycyrrhizic Acid; Metabolic Engineering; Oleanolic Acid; Plant Proteins; Plant Roots; Plants, Genetically Modified

2018