Page last updated: 2024-08-21

oleanolic acid and dinoprostone

oleanolic acid has been researched along with dinoprostone in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's8 (25.81)18.2507
2000's11 (35.48)29.6817
2010's9 (29.03)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Ohuchi, K; Ozeki, T; Tsurufuji, S; Watanabe, M1
Haque, MS; Kitazawa, Y; Okada, K; Sugiyama, K; Taniguchi, T1
Haque, SR; Hayakawa, T; Kitazawa, Y; Okada, K; Sugiyama, K; Taniguchi, T1
Haque, MS; Kitazawa, Y; Nakai, Y; Okada, K; Sugiyama, K; Taniguchi, T1
Masuda, K; Oshika, T; Shoji, N1
Abad Martínez, MJ; Bermejo Benito, P; Díaz Lanza, AM; Fernández Matellano, L; Sánchez Contreras, S; Sanz Gómez, A; Silván Sen, AM1
Alcaraz, MJ; Garcia-Pastor, P; Gomez-Paloma, L; Paya, M; Randazzo, A1
Amano, S; Masuda, K; Oshika, T; Shoji, N1
Kodama, Y; Kubo, M; Kyo, R; Nakahata, N; Nakai, Y; Ohizumi, Y1
Ban, HS; Kim, SY; Kim, YP; Lee, EB; Li, D; Lim, SS; Ohuchi, K; Shin, KH1
Choi, JW; Ha, JH; Kim, RG; Kim, YK; Lee, KT; Park, HJ; Park, SJ1
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Alcaraz, MJ; Gomez-Paloma, L; Payá, M; Posadas, I; Randazzo, A; Terencio, MC1
Kodama, Y; Nakahata, N; Ohizumi, Y; Tsuchiya, C; Xiaochuan, L; Yoshida, M1
Jiang, YY; Wang, HB; Xiao, ZY; Yin, M; Zhang, JP; Zheng, QY; Zhou, B1
Delgado, R; Delporte, C; García, D; Garrido, G; González, D; Lemus, Y; Lodeiro, L; Núñez-Sellés, AJ; Quintero, G1
Razmilic, I; Rodríguez, JA; Sánchez, M; Schmeda-Hirschmann, G; Theoduloz, C; Yáñez, T1
Kodama, Y; Lv, X; Nakahata, N; Ohizumi, Y; Toriniwa, Y; Yoshida, M1
Avellar, MC; Calixto, JB; Medeiros, R; Otuki, MF1
Bland, JS; Carroll, B; Darland, G; Hall, A; Katke, J; Lamb, J; Lerman, RH; Minich, DM; Tripp, M1
Andrés, RM; Aquino, M; Bruno, I; De Simone, R; Guerrero, MD; Paya, M; Riccio, R; Terencio, MC1
Bai, Q; Li, G; Lü, C; Xu, H; Yao, X1
Hwang, KA; Hwang, YJ; Kim, HR; Song, J1
Cai, J; Cao, W; Chen, J; Chu, X; Deng, H; Li, X; Liu, Z; Mao, L; Sun, S; Zha, L1
Helen, A; Krishnan, K; Mathew, LE; Vijayalakshmi, NR1
Liu, J; Ma, Z; Piao, T; Wang, Y1
Jang, DS; Lee, HJ; Lee, KT; Lee, WS; Park, JM; Shim, HY; Shin, JS1
Chen, Y; Xu, Y; Yang, H; Yu, L1
Chang, SL; Chen, YI; Hsu, TH; Hung, PH; Lin, CM; Tsai, JC; Tzeng, CY1
Chen, H; Lei, H; Su, J; Xu, G; Yuan, Q1

Trials

1 trial(s) available for oleanolic acid and dinoprostone

ArticleYear
Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Blood Coagulation; Blood Pressure; Cells, Cultured; Cross-Over Studies; Cyclopentanes; Dinoprostone; Double-Blind Method; Drug Combinations; Feces; Female; Humans; Humulus; Kidney Function Tests; Leukocyte L1 Antigen Complex; Liver Function Tests; Male; Mice; Naproxen; Oleanolic Acid; Pain; Plant Extracts; Rheumatic Diseases; Rosmarinus

2007

Other Studies

30 other study(ies) available for oleanolic acid and dinoprostone

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Pharmacological influence of saikosaponins on prostaglandin E2 production by peritoneal macrophages.
    Planta medica, 1985, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; In Vitro Techniques; Macrophages; Male; Mice; Muscle Contraction; Muscle, Smooth; Oleanolic Acid; Prostaglandins E; Rats; Rats, Inbred Strains; Sapogenins; Saponins

1985
Intraocular pressure response to intravitreal injection of endothelin-1 and the mediatory role of ETA receptor, ETB receptor, and cyclooxygenase products in rabbits.
    Current eye research, 1995, Volume: 14, Issue:6

    Topics: Animals; Aqueous Humor; Caffeic Acids; Dinoprostone; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Female; Indomethacin; Injections; Intraocular Pressure; Male; Oleanolic Acid; Prostaglandin-Endoperoxide Synthases; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstrictor Agents; Viper Venoms; Vitreous Body

1995
[The effect of an endothelin receptor antagonist, 97-139, on intraocular pressure in rabbits].
    Nippon Ganka Gakkai zasshi, 1995, Volume: 99, Issue:3

    Topics: Animals; Aqueous Humor; Caffeic Acids; Dinoprostone; Endothelin Receptor Antagonists; Endothelins; Female; Intraocular Pressure; Male; Oleanolic Acid; Rabbits

1995
The effects of ETB receptor-selective agonist on IOP and blood-aqueous barrier in rabbit eyes: role of cyclooxygenase products.
    Japanese journal of ophthalmology, 1995, Volume: 39, Issue:4

    Topics: Animals; Aqueous Humor; Blood-Aqueous Barrier; Caffeic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Endothelin-1; Eye Proteins; Female; Indomethacin; Intraocular Pressure; Male; Oleanolic Acid; Prostaglandin-Endoperoxide Synthases; Rabbits; Receptors, Endothelin; Vasoconstrictor Agents; Viper Venoms

1995
[Anterior chamber inflammation after the injection of endothelin-1 into the vitreous and the effect of ETA receptor antagonist].
    Nippon Ganka Gakkai zasshi, 1997, Volume: 101, Issue:4

    Topics: Animals; Anterior Chamber; Aqueous Humor; Caffeic Acids; Dinoprostone; Endothelin Receptor Antagonists; Endothelin-1; Female; Inflammation; Leukotriene B4; Male; Oleanolic Acid; Rabbits; Receptor, Endothelin A; Receptors, Endothelin; Vitreous Body

1997
In vivo and in vitro antiinflammatory activity of saikosaponins.
    Life sciences, 1998, Volume: 63, Issue:13

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Sequence; Cell Survival; Cells, Cultured; Dinoprostone; Ear, External; Edema; Female; Humans; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Molecular Sequence Data; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins; Tetradecanoylphorbol Acetate

1998
Effects of petrosaspongiolide M, a novel phospholipase A2 inhibitor, on acute and chronic inflammation.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Survival; Dinoprostone; Edema; Enzyme Inhibitors; Exudates and Transudates; Humans; In Vitro Techniques; Inflammation; Leukocytes; Leukotriene B4; Male; Mice; Oleanolic Acid; Phospholipases A; Phospholipases A2; Porifera; Rats; Rats, Inbred Lew; Rats, Wistar; Tumor Necrosis Factor-alpha; U937 Cells

1999
Effects of endothelin receptor antagonists on anterior chamber inflammation induced by intravitreal injection of endothelin-1.
    Experimental eye research, 1999, Volume: 69, Issue:4

    Topics: Animals; Caffeic Acids; Dinoprostone; Endothelin Receptor Antagonists; Endothelin-1; Eye Proteins; Female; Leukotriene B4; Male; Oleanolic Acid; Oligopeptides; Piperidines; Rabbits; Receptors, Endothelin; Uveitis, Anterior

1999
Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Drug Antagonism; Flavanones; Flavonoids; Glioma; Oleanolic Acid; Prostaglandin Antagonists; Rats; Sapogenins; Saponins; Tumor Cells, Cultured

1999
Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
    Planta medica, 2001, Volume: 67, Issue:4

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Drugs, Chinese Herbal; Enzyme Induction; Indomethacin; Isoenzymes; Macrophages, Peritoneal; Membrane Proteins; Oleanolic Acid; Plant Roots; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Saponins; Tetradecanoylphorbol Acetate; Triterpenes

2001
In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Araliaceae; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oleanolic Acid; Plant Bark; Prostaglandin-Endoperoxide Synthases; Saponins; Tumor Necrosis Factor-alpha

2002
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Inhibition of the NF-kappaB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M.
    Biochemical pharmacology, 2003, Mar-01, Volume: 65, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Biological Transport; Cell Movement; Cyclooxygenase 2; Cytokines; Dinoprostone; DNA; I-kappa B Proteins; Isoenzymes; Macrophages, Peritoneal; Mice; Models, Animal; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oleanolic Acid; Phosphorylation; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha; Zymosan

2003
Dual effect of saikogenin D: in vitro inhibition of prostaglandin E2 production and elevation of intracellular free Ca2+ concentration in C6 rat glioma cells.
    Planta medica, 2003, Volume: 69, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupleurum; Calcium; Cell Line, Tumor; Dinoprostone; Dose-Response Relationship, Drug; Glioma; Oleanolic Acid; Phytotherapy; Plant Roots; Prostaglandin Antagonists; Rats

2003
Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E2.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprostone; Drugs, Chinese Herbal; Female; Interferon-gamma; Interleukin-1; Interleukin-2; Lymphocytes; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Oleanolic Acid; Phytolacca; Plants, Medicinal; Saponins

2004
In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG).
    Pharmacological research, 2004, Volume: 50, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cuba; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ear, External; Edema; Eicosanoids; Indomethacin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Mangifera; Mice; Oleanolic Acid; Peroxidase; Phospholipases A; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water; Xanthones

2004
Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships.
    Life sciences, 2006, Aug-29, Volume: 79, Issue:14

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cell Line; Cell Proliferation; Cell Survival; Central Nervous System Depressants; Chemical Phenomena; Chemistry, Physical; Dinoprostone; Epithelial Cells; Ethanol; Fibroblasts; Free Radical Scavengers; Gastric Mucosa; Glutathione; Humans; Hydrochloric Acid; Lansoprazole; Male; Mice; Oleanolic Acid; Omeprazole; Stomach Ulcer; Superoxides; Taurocholic Acid

2006
Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dinoprostone; Enzyme Activation; Oleanolic Acid; Oxygenases; Proadifen; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger

2006
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
    European journal of pharmacology, 2007, Mar-22, Volume: 559, Issue:2-3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; NF-kappa B; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Skin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA

2007
Toward the discovery of new agents able to inhibit the expression of microsomal prostaglandin E synthase-1 enzyme as promising tools in drug development.
    Chemical biology & drug design, 2010, Volume: 76, Issue:1

    Topics: 4-Butyrolactone; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Drug Discovery; Gene Expression; Intramolecular Oxidoreductases; Macrophages; Mice; Microsomes; Oleanolic Acid; Prostaglandin-E Synthases; Thiophenes

2010
Taraxerol inhibits LPS-induced inflammatory responses through suppression of TAK1 and Akt activation.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 2; Cytokines; Dinoprostone; Down-Regulation; Inflammation; Lipopolysaccharides; Macrophages; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oleanolic Acid; Oncogene Protein v-akt; RNA, Messenger

2013
Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells.
    BMB reports, 2014, Volume: 47, Issue:9

    Topics: Acetylation; Animals; Anti-Inflammatory Agents; Cell Line; Dinoprostone; Down-Regulation; MafK Transcription Factor; Mice; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Oleanolic Acid; Oxidative Stress; Prunella; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription Factor RelA

2014
Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Cell Line; Chromones; Cyclooxygenase 2; Dinoprostone; Glycine max; I-kappa B Kinase; Inflammation; Lipopolysaccharides; Macrophages; Malondialdehyde; Mice; Morpholines; Nitriles; Oleanolic Acid; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Saponins; Signal Transduction; Sulfones; Superoxide Dismutase; Transcription Factor RelA

2014
Anti-inflammatory potential of β-amyrin, a triterpenoid isolated from Costus igneus.
    Inflammopharmacology, 2014, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Costus; Diclofenac; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Humans; India; Inflammation; Interleukin-6; Leukocytes, Mononuclear; Male; Medicine, Traditional; NF-kappa B; Oleanolic Acid; Plant Leaves; Rats; Rats, Sprague-Dawley

2014
Echinocystic Acid Inhibits IL-1β-Induced COX-2 and iNOS Expression in Human Osteoarthritis Chondrocytes.
    Inflammation, 2016, Volume: 39, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 13; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Osteoarthritis; p38 Mitogen-Activated Protein Kinases

2016
Chikusetsusaponin IVa Methyl Ester Isolated from the Roots of Achyranthes japonica Suppresses LPS-Induced iNOS, TNF-α, IL-6, and IL-1β Expression by NF-κB and AP-1 Inactivation.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Achyranthes; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Dinoprostone; Esters; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oleanolic Acid; Plant Roots; RAW 264.7 Cells; Saponins; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2016
Esculentoside A exerts anti-inflammatory activity in microglial cells.
    International immunopharmacology, 2017, Volume: 51

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Dinoprostone; Humans; Lipopolysaccharides; Microglia; Neurodegenerative Diseases; Neurogenic Inflammation; NF-kappa B; Nitric Oxide; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Phytolaccaceae; Rats; Saponins; Signal Transduction

2017
Acetylsalicylic acid-like analgesic effects of Trametes versicolor in Wistar rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Analgesics; Animals; Aspirin; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Down-Regulation; Male; Oleanolic Acid; Pain; Pain Threshold; Polyporaceae; Rats, Wistar

2020
Inhibition of chikusetsusaponin IVa on inflammatory responses in RAW264.7 cell line via MAPK pathway.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2021, Mar-26, Volume: 76, Issue:3-4

    Topics: Animals; Dinoprostone; Humans; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mitogen-Activated Protein Kinase Kinases; Nitric Oxide; Oleanolic Acid; RAW 264.7 Cells; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha

2021