Page last updated: 2024-08-21

oleanolic acid and dimethyl fumarate

oleanolic acid has been researched along with dimethyl fumarate in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Huang, J; Ma, H; Wang, Y; Wang, Z; Yao, Z; Yu, J; Zhang, L; Zhang, W; Zhuang, C1
Kensler, TW; Motohashi, H; Onodera, K; Satomi, S; Suzuki, T; Takaya, K; Yamamoto, M1
Liby, KT; Ringelberg, CS; Risingsong, R; Royce, DB; Sporn, MB; To, C; Williams, CR1
Mashino, T; Obata, R; Ohe, T; Takahashi, K; Yasuda, D1
Basagni, F; Lanni, C; Minarini, A; Rosini, M1
Campagna, R; Chlopicki, S; Grosicki, M; Jamrozik, M; Kaczara, P; Stojak, M; Szczesny-Malysiak, E1

Reviews

2 review(s) available for oleanolic acid and dimethyl fumarate

ArticleYear
[Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:8

    Topics: 1-Naphthylamine; Autophagy; Dimethyl Fumarate; Drug Discovery; High-Throughput Screening Assays; Humans; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Microsomes, Liver; NF-E2-Related Factor 2; Oleanolic Acid; Phosphorylation; Protein Interaction Maps; Sequestosome-1 Protein; Sulfonamides; Sulfoxides

2018
Lights and shadows of electrophile signaling: focus on the Nrf2-Keap1 pathway.
    Future medicinal chemistry, 2019, Volume: 11, Issue:7

    Topics: Animals; Antioxidants; Cysteine; Dimethyl Fumarate; Drug Design; Humans; Kelch-Like ECH-Associated Protein 1; Molecular Structure; NF-E2-Related Factor 2; Oleanolic Acid; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Structure-Activity Relationship

2019

Other Studies

4 other study(ies) available for oleanolic acid and dimethyl fumarate

ArticleYear
Discovery of bardoxolone derivatives as novel orally active necroptosis inhibitors.
    European journal of medicinal chemistry, 2021, Feb-15, Volume: 212

    Topics: Administration, Oral; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Necroptosis; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Systemic Inflammatory Response Syndrome

2021
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.
    Free radical biology & medicine, 2012, Aug-15, Volume: 53, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Antioxidants; Azoles; Cytoskeletal Proteins; Dimethyl Fumarate; Fumarates; Gene Expression; Gene Expression Regulation; Glutamate-Cysteine Ligase; HEK293 Cells; Humans; Hydroquinones; Imidazoles; Isoindoles; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Macrophages, Peritoneal; Maleates; Mice; Mice, Transgenic; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oleanolic Acid; Organoselenium Compounds; Oxidants; Oxidative Stress; Sulfoxides; Transcriptional Activation

2012
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
    Carcinogenesis, 2015, Volume: 36, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Dimethyl Fumarate; Female; Fumarates; Gene Expression Regulation, Neoplastic; Imidazoles; Lung Neoplasms; Mice, Inbred Strains; Mice, Knockout; Molecular Targeted Therapy; Neoplasms, Experimental; NF-E2-Related Factor 2; Oleanolic Acid; Oligonucleotide Array Sequence Analysis; Oxidative Stress

2015
Bardoxolone Methyl Displays Detrimental Effects on Endothelial Bioenergetics, Suppresses Endothelial ET-1 Release, and Increases Endothelial Permeability in Human Microvascular Endothelium.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Cell Line; Cell Survival; Dimethyl Fumarate; Down-Regulation; Endothelial Cells; Endothelin-1; Gene Expression; Humans; Isothiocyanates; Membrane Potential, Mitochondrial; Microvessels; Mitochondria; NF-E2-Related Factor 2; Oleanolic Acid; Permeability; Reactive Oxygen Species; Sulfoxides

2020