oleanolic acid has been researched along with cytochrome c-t in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 15 (71.43) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huat, BT; Swamy, SM | 1 |
| Fujii, M; Hou, DX; Lin, S; Tong, X | 1 |
| Cai, TT; Sun, Y; Xu, Q; Zhou, XB | 1 |
| Chu, R; Climent, J; Cohen, I; Fong, S; Griffin, C; Leitman, D; Shoemaker, M; Shtivelman, E; Staub, RE; Zhao, X | 1 |
| Delebinski, CI; Henze, G; Jaeger, S; Kemnitz-Hassanin, K; Lode, HN; Seifert, GJ | 1 |
| Liu, Y; Su, B; Wang, X | 1 |
| Bae, ON; Chung, JH; Kang, S; Kim, K; Lim, KM; Noh, JY; Song, JS | 1 |
| Han, L; Lin, X; Liu, H; Liu, M; Wang, F; Wang, H; Wei, J; Zhang, Y | 1 |
| Chu, E; Han, L; Lin, X; Liu, H; Liu, M; Wei, J; Wu, N; Xiao, L; Zhao, J | 1 |
| Bai, H; Cao, P; Hai, C; Liao, N; Liu, J; Wang, X; Wang, Z; Zhang, W; Zhang, X | 1 |
| Cheng, L; Ding, Q; Liang, XQ; Shi, L; Wang, Y; Wang, YF; Xia, TS; Xue, JQ; Zhou, W | 1 |
| Chen, JY; Qin, LP; Su, L; Zhang, H; Zhang, L | 1 |
| Cao, L; Gao, H; Qu, S; Yang, J; Yao, M; Zhang, L | 1 |
| Bai, CH; He, HB; Wang, JZ; Wang, S; Wei, N; Xiao, SZ; Zou, K | 1 |
| Lin, XK; Liu, G; Liu, J; Ma, LN; Wu, N; Zheng, LH; Zhong, JT | 1 |
| Huang, HY; Wu, YL; Zhu, YY | 1 |
| Chen, X; Han, Y; Han, Z; Jiang, Q; Kong, D; Wang, C; Wang, Q | 1 |
| Dong, W; Liu, H; Wang, J; Wu, D; Wu, J; Zhang, J | 1 |
| Deng, H; Dong, W; Li, J; Ma, J; Wang, J; Wu, D; Zhang, J | 1 |
| Feng, B; Li, J; Tian, T; Yu, J; Zhang, X; Zhang, Y; Zhao, C; Zhao, L | 1 |
| Bu, Y; Guo, J; Hu, J; Li, B; Li, J; Zhang, H; Zhang, Y | 1 |
21 other study(ies) available for oleanolic acid and cytochrome c-t
| Article | Year |
|---|---|
Intracellular glutathione depletion and reactive oxygen species generation are important in alpha-hederin-induced apoptosis of P388 cells.
Topics: Animals; Apoptosis; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Humans; Intracellular Membranes; Leukemia P388; Mice; Mitochondria; Nigella sativa; Oleanolic Acid; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Saponins; Tumor Cells, Cultured | 2003 |
Echinocystic acid induces apoptosis in HL-60 cells through mitochondria-mediated death pathway.
Topics: Antioxidants; Apoptosis; Cytochromes c; DNA Damage; HL-60 Cells; Humans; Mitochondria; Oleanolic Acid; Poly(ADP-ribose) Polymerases | 2004 |
Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis.
Topics: Animals; Apoptosis; Autoimmune Diseases; Bupleurum; Cell Cycle; Cell Proliferation; Cyclin D3; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Female; Immunosuppression Therapy; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Oleanolic Acid; Saponins; T-Lymphocytes; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cholesterol; Cytochromes c; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluorescent Antibody Technique; Gleditsia; Humans; Mechanistic Target of Rapamycin Complex 1; Membrane Microdomains; Membrane Potential, Mitochondrial; Multiprotein Complexes; Oleanolic Acid; Plant Extracts; Proteins; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Cells, Cultured | 2010 |
A new development of triterpene acid-containing extracts from Viscum album L. displays synergistic induction of apoptosis in acute lymphoblastic leukaemia.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Drug Synergism; Female; Humans; Membrane Potential, Mitochondrial; Mice; Mice, SCID; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Lectins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solubility; Triterpenes; Viscum album; Xenograft Model Antitumor Assays | 2012 |
Study on the noncovalent interactions of saikosaponins and cytochrome c by electrospray ionization mass spectrometry.
Topics: Animals; Bupleurum; Cytochromes c; Horses; Oleanolic Acid; Oligosaccharides; Protein Binding; Saponins; Spectrometry, Mass, Electrospray Ionization; Triterpenes | 2012 |
Procoagulant and prothrombotic effects of the herbal medicine, Dipsacus asper and its active ingredient, dipsacus saponin C, on human platelets.
Topics: Adenosine Triphosphate; Adolescent; Adult; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Blood Coagulation; Blood Platelets; Calcium; Caspase 3; Cell-Derived Microparticles; Chelating Agents; Coagulants; Cytochromes c; Dipsacaceae; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Male; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; Partial Thromboplastin Time; Phosphatidylserines; Phospholipid Transfer Proteins; Plant Preparations; Plant Roots; Platelet Activation; Prothrombin Time; Rats; Rats, Sprague-Dawley; Risk Assessment; Risk Factors; Saponins; Thrombosis; Time Factors; Young Adult | 2012 |
Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells.
Topics: Apoptosis; Caspase 3; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cytochromes c; DNA Fragmentation; Humans; Lysosomes; Mitochondria; Oleanolic Acid; Pancreatic Neoplasms; Reactive Oxygen Species | 2013 |
Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cathepsin D; Cell Proliferation; Cytochromes c; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Intracellular Membranes; Lysosomes; NF-kappa B; Oleanolic Acid; Pancreatic Neoplasms; Permeability; Proto-Oncogene Proteins c-bcl-2; Survivin; Tumor Cells, Cultured | 2012 |
Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin B1; Cyclooxygenase 2; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neoplasm Transplantation; Oleanolic Acid; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2013 |
The apoptotic effect of D Rhamnose β-hederin, a novel oleanane-type triterpenoid saponin on breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptotic Protease-Activating Factor 1; Breast Neoplasms; Caspase 3; Caspase 9; Chromones; Cytochromes c; Drug Screening Assays, Antitumor; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Female; Humans; MAP Kinase Signaling System; MCF-7 Cells; Membrane Potential, Mitochondrial; Morpholines; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Saponins | 2014 |
Triggering of p38 MAPK and JNK signaling is important for oleanolic acid-induced apoptosis via the mitochondrial death pathway in hypertrophic scar fibroblasts.
Topics: Anthracenes; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line; Cicatrix, Hypertrophic; Cytochromes c; Fibroblasts; Humans; Imidazoles; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction | 2014 |
Saikosaponin‑d inhibits proliferation of DU145 human prostate cancer cells by inducing apoptosis and arresting the cell cycle at G0/G1 phase.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; G1 Phase Cell Cycle Checkpoints; Humans; Male; Membrane Potential, Mitochondrial; Oleanolic Acid; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Saponins; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Comparison of cardioprotective effects of labeled and unlabeled oleanoic acids with new BOPIM dye on primary neonatal rat cardiomyocytes following hypoxia/reoxygenation injury.
Topics: Animals; Animals, Newborn; Apoptosis; Boron Compounds; Cardiotonic Agents; Cell Hypoxia; Cell Survival; Cells, Cultured; Cytochromes c; Fluorescent Dyes; Membrane Potential, Mitochondrial; Molecular Structure; Myocytes, Cardiac; Oleanolic Acid; Oxygen; Primary Cell Culture; Rats; Reactive Oxygen Species; Staining and Labeling | 2014 |
p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Cytochromes c; Humans; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Membrane Proteins; Mitochondria; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2014 |
Anticancer and apoptotic activities of oleanolic acid are mediated through cell cycle arrest and disruption of mitochondrial membrane potential in HepG2 human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; Propidium; Reactive Oxygen Species; Rhodamine 123 | 2015 |
Cytoprotective Effects of Oleanolic Acid in Human Umbilical Vascular Endothelial Cells is Mediated Via UCP2/ROS/Cytochrome C/AIF Pathway.
Topics: Antioxidants; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Cytochromes c; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Mitochondria; Oleanolic Acid; Reactive Oxygen Species; Uncoupling Protein 2 | 2016 |
α-Hederin Induces Apoptosis of Esophageal Squamous Cell Carcinoma via an Oxidative and Mitochondrial-Dependent Pathway.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Flow Cytometry; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mice, Nude; Mitochondria; Neoplasm Transplantation; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Saponins; Xenograft Model Antitumor Assays | 2019 |
α-Hederin induces the apoptosis of gastric cancer cells accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Saponins; Stomach Neoplasms | 2020 |
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Proliferation; Cytochromes c; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Ursolic Acid | 2020 |
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Cytochromes c; Glucose; Mice; Mitochondria; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury; Saponins | 2022 |