Page last updated: 2024-08-21

oleanolic acid and cyclin d1

oleanolic acid has been researched along with cyclin d1 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andreeff, M; Gold, D; Konopleva, M; Lapillonne, H; Madden, T; McQueen, T; Sutherland, RL; Tsao, T1
Abdelrahim, M; Andreeff, M; Hung, MC; Johansen, M; Konopleva, M; Madden, T; McQueen, T; Munsell, MF; Safe, SH; Shi, YX; Tsao, T; Yu, D; Zhang, W1
Lee, JH; Min, BS; Ryoo, S; Seo, J; Tae, N1
Andreeff, M; Dezube, BJ; Eder, JP; Ferguson, DA; He, X; Hong, DS; Konoplev, S; Konopleva, M; Kufe, D; Kurzrock, R; Lawrence, D; Lazarus, H; Meyer, CJ; Mier, J; Naing, A; Shapiro, GI; Supko, JG; Wheler, J1
Chen, P; Chen, X; Lin, LG; Lu, JJ; Meng, FC; Qiang, WA; Tang, ZH; Wang, YT; Wu, QS; Zhang, QW1
Das, V; Ghosh, S; Giri, B; Kumar, A; Mandal, A; Mukhopadhyay, S; Sarkar, M1
Du, H; Duan, Z; Fan, X; Jiang, J; Lei, H; Li, H; Sun, Y; Wang, P; Wang, Z1
Choi, J; Gee, MS; Inn, KS; Kang, SB; Kim, BJ; Kim, N; Kim, NJ; Lee, JK1
Dong, W; Liu, H; Wang, J; Wu, D; Wu, J; Zhang, J1

Trials

1 trial(s) available for oleanolic acid and cyclin d1

ArticleYear
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-15, Volume: 18, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Colorectal Neoplasms; Cyclin D1; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Janus Kinases; Kidney Neoplasms; Lymphoma; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; RNA, Messenger; STAT Transcription Factors; Thyroid Neoplasms; Young Adult

2012

Other Studies

8 other study(ies) available for oleanolic acid and cyclin d1

ArticleYear
Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
    Cancer research, 2003, Sep-15, Volume: 63, Issue:18

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Division; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Immunocompromised Host; Mice; Mice, Nude; Oleanolic Acid; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2003
Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: Animals; Breast Neoplasms; Caveolin 1; Cell Proliferation; Cyclin D1; Female; Humans; Mice; Mice, Mutant Strains; Oleanolic Acid; Phosphorylation; PPAR gamma; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; RNA, Messenger; Transcriptional Activation; Xenograft Model Antitumor Assays

2006
3-Oxoolean-12-en-27-oic acid inhibits the proliferation of non-small cell lung carcinoma cells by inducing cell-cycle arrest at G0/G1 phase.
    Anticancer research, 2011, Volume: 31, Issue:6

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cyclin D1; Cyclin E; Down-Regulation; G1 Phase; Humans; Lung Neoplasms; Oleanolic Acid; Resting Phase, Cell Cycle; Retinoblastoma Protein

2011
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase 2; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; G1 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Saponins

2016
Biological evaluation of a halogenated triterpenoid, 2α-bromo-dihydrobelulonic acid as inhibitor of human topoisomerase IIα and HeLa cell proliferation.
    Chemico-biological interactions, 2017, Apr-25, Volume: 268

    Topics: Antigens, Neoplasm; Apoptosis; Betulinic Acid; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; G1 Phase Cell Cycle Checkpoints; Halogenation; HeLa Cells; Humans; Intercalating Agents; Oleanolic Acid; Pentacyclic Triterpenes; Proliferating Cell Nuclear Antigen; Spectrometry, Fluorescence; Streptophyta; Topoisomerase II Inhibitors; Triterpenes

2017
Oleanolic acid derivatives inhibit the Wnt/β-catenin signaling pathway by promoting the phosphorylation of β-catenin in human SMMC-7721 cells.
    Die Pharmazie, 2016, Jul-07, Volume: 71, Issue:7

    Topics: beta Catenin; Cell Line, Tumor; Cell Nucleus; Cyclin D1; Cytoplasm; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Oleanolic Acid; Phosphorylation; Proto-Oncogene Proteins c-myc; RNA, Messenger; Wnt Signaling Pathway

2016
Bardoxolone Methyl Suppresses Hepatitis B Virus Large Surface Protein Variant W4P-Related Carcinogenesis and Hepatocellular Carcinoma Cell Proliferation Via the Inhibition of Signal Transducer and Activator of Transcription 3 Signaling.
    Pharmacology, 2018, Volume: 102, Issue:1-2

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Genetic Variation; Humans; Mice; Oleanolic Acid; Signal Transduction; STAT3 Transcription Factor; Stem Cells; Tumor Suppressor Protein p53; Viral Envelope Proteins

2018
α-Hederin Induces Apoptosis of Esophageal Squamous Cell Carcinoma via an Oxidative and Mitochondrial-Dependent Pathway.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Flow Cytometry; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mice, Nude; Mitochondria; Neoplasm Transplantation; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Saponins; Xenograft Model Antitumor Assays

2019