Page last updated: 2024-08-21

oleanolic acid and beta-amyrin

oleanolic acid has been researched along with beta-amyrin in 235 studies

Research

Studies (235)

TimeframeStudies, this research(%)All Research%
pre-199010 (4.26)18.7374
1990's16 (6.81)18.2507
2000's60 (25.53)29.6817
2010's130 (55.32)24.3611
2020's19 (8.09)2.80

Authors

AuthorsStudies
Hata, K; Hori, K; Takahashi, S1
Habib-Jiwan, JL; Hoet, S; Muccioli, GG; Opperdoes, FR; Pieters, L; Quetin-Leclercq, J1
Bastida, J; da Silva, GN; da Silva, MV; Gnoatto, SC; Lopes, NP; Macedo, AJ; Silva, DB; Silva, NL; Tasca, T; Vieira, Pde B1
Ding, J; Hu, JF; Li, J; Ma, GL; Wan, J; Wang, PP; Xiong, J1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Feng, F; Liu, Y; Lu, X; Qiao, Y; Qin, N; Qu, W; Sun, H1
Kweifio-Okai, G; Macrides, TA1
Ohizumi, Y; Oshima, Y; Subarnas, A1
Chen, Y; Shang, S1
Chen, G; Ding, W; Ruan, J1
Chen, J; Chen, SF; Geng, GL; He, CH; Xi, FD; Ye, GH; Zheng, QT1
Evans, JL; Gealt, MA1
Auguścińska, E; Kasprzyk, Z1
Gealt, MA1
Ambrose, R; Bird, D; Carroll, AR; Eu, P; Field, B; Kweifio-Okai, G1
Cropley, M; De Munk, F; Kweifio-Okai, G; Macrides, TA; Rumble, BA1
Ding, WP; Ruan, JL; Zhang, YE1
Ebizuka, Y; Kushiro, T; Shibuya, M1
Ammon, HP; Boden, SE; Safayhi, H; Sailer, ER; Schweizer, S1
Ammon, HP; Dannecker, GE; Hoernlein, RF; Niethammer, D; Orlikowsky, T; Sailer, ER; Simmet, T; Zehrer, C1
Hasmeda, M; Kweifio-Okai, G; Macrides, T; Polya, GM1
Ebizuka, Y; Kushiro, T; Masuda, K; Morita, M; Shibuya, M1
Chen, Y; Li, B; Wang, M; Zhang, J1
Benveniste, P; Husselstein-Muller, T; Schaller, H1
El-Emary, NA; Hame, AI; Hassan, HA; Mitome, H; Miyaoka, H; Springue, IV1
Jha, RN; Pandey, MB; Pandey, VB; Upadhyay, RK1
Boreham, CJ; Freeman, KH; Hayes, JM; Summons, RE1
Du, H; Jiang, P; Yuan, S1
Balakrishna, K; Brindha, P; Lakshmanaperumalsamy, P; Ramesh, N; Saraswathy, A; Viswanathan, MB1
Beveridge, TH; Drover, JC; Li, TS1
Williams, N1
Guo, Y; Lin, L; Shen, J1
Choudhary, MI; Fatima, N; Lontsi, D; Sondengam, BL; Tapondjou, LA1
Osbourn, AE1
Achnine, L; Dixon, RA; Matsuda, SP; Suzuki, H; Xu, R1
Wang, R; Zhang, D1
Sabir, AW; Saeed, MA1
Tian, JK; Xu, LZ; Yang, SL; Zou, ZM1
MEDAKOVIC, B; MOKRANJAC, MS1
BAISTED, DJ; CAPSTACK, E; NES, WR1
BLONDIN, GA; CAPSTACKE, JR; NES, WR; ROSIN, N1
Braekman, JC; Daloze, D; Dooms, C; Habib-Jiwan, JL; Laurent, P; Pasteels, JM; Rozenberg, R; Termonia, A1
Chen, RY; Sun, SG; Wu, F1
Doubek, DL; Duke, JA; Herald, DL; Pettit, GR; Pinilla, V; Zhang, Q1
Almeida, FR; Chaves, MH; Cordeiro, WM; Lima-Junior, RC; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM; Vieira-Júnior, GM1
Almeida, FR; Chaves, MH; Martins, FS; Oliveira, FA; Rao, VS; Santos, FA; Santos, KA; Silva, RM; Vieira-Júnior, GM1
Jamil, K; Mahapatra, A; Mallavadhani, UV; Reddy, PS1
Calixto, JB; Cani, GS; Ferreira, J; Lima, FV; Malheiros, A; Meyre-Silva, C; Muller, LA; Otuki, MF; Santos, AR; Yunes, RA1
Calixto, JB; Malheiros, A; Otuki, MF; Vieira-Lima, F; Yunes, RA1
Almeida, FR; Brito, GA; Chaves, MH; Lima, RC; Maia, JL; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM1
Gören, AC; Kingston, DG; Kökdil, G; Topçu, G; Zhou, BN1
Almeida, FR; Campos, AR; Cavalcante, IJ; Chaves, MH; Costa, CL; Lima, AF; Lima, RC; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM1
Cai, Y; Ruan, J1
Mensink, RP; Nichols, JA; Plat, J1
Bringmann, G; Dreyer, M; Guhling, O; Jetter, R; Kinzler, C1
Crevelin, EJ; Crotti, AE; Cunha, WR; Lopes, JL; Lopes, NP; Turatti, IC; Veneziani, RC1
Campos, DA; Cavalcante, IJ; Chaves, MH; Gurgel, LA; Lima-Júnior, RC; Oliveira, FA; Rao, VS; Santos, FA; Santos, KA; Silva, RM; Vale, CA1
Kong, LY; Li, WJ; Lu, J; Xu, LL1
Ebizuka, Y; Hayashi, H; Hoshino, M; Katsube, Y; Kushiro, T; Shibuya, M1
Bu, PB; Li, C; Sun, YF; Yue, DK1
Huang, JP; Jiang, JS; Ma, YM; Zhang, PC1
Aragão, GF; Bandeira, PN; Carneiro, LM; Junior, AP; Lemos, TL; Viana, GS; Vieira, LC1
Wang, JX; Wei, YX1
Avellar, MC; Calixto, JB; Medeiros, R; Otuki, MF1
Ebizuka, Y; Katsube, Y; Otsuka, M; Shibuya, M; Xiang, T; Zhang, H1
Calixto, JB; Frizzo, ME; Jung, F; Martini, LH; Rotta, LN; Soares, FA; Souza, DO; Vendite, DA; Wofchuk, S; Yunes, RA1
Johann, S; Lyon, JP; Pizzolatti, MG; Resende, MA; Soldi, C1
Martelanc, M; Simonovska, B; Vovk, I1
Chen, HS; Du, JL; Jin, L; Jin, YS; Liang, S; Lu, J1
Masuda, K; Muranaka, T; Ohyama, K; Suzuki, M; Yoshida, S1
Lou, FM; Niu, YK; Yang, J1
Gu, K; Huang, XZ; Li, C; Tan, LX1
Chaves, MH; Cunha, GM; Holanda Pinto, SA; Pinto, LM; Rao, VS; Santos, FA1
Cáceres-Castillo, D; Cedillo-Rivera, R; Mena-Rejón, GJ; Quijano, L1
Luiz, AP; Marcon, R; Meotti, FC; Mioto, LA; Pizzolatti, MG; Santos, AR; Soldi, C1
Chaves, MH; Cunha, GM; Guedes, MA; Holanda Pinto, SA; Pinto, LM; Rao, VS; Santos, FA1
Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI1
Aragão, GF; Cunha Pinheiro, MC; de Barros Viana, GS; Gomes Lemos, TL; Nogueira Bandeira, P1
BURRELL, RC; HOUSTON, FG1
Agarwal, SC; Chaturvedi, JP; Joshi, MD; Khaliq, T; Maurya, R; Mishra, P; Narender, T; Singh, AB; Srivastava, AK1
Ebizuka, Y; Katsube, Y; Otsuka, M; Shibuya, M; Tansakul, P; Xiang, T; Zhang, H1
Bi, SN; Liu, WH; Shao, S; Wang, HJ; Yan, MM; Zhao, DQ1
Kordower, JH; Masliah, E; McKay, H; Merrill, DA; Mufson, EJ; Roberts, JA; Tuszynski, MH1
Chung, IM; Kim, MY; Moon, HI; Park, SD; Park, WH1
Maurya, R; Singh, AB; Srivastava, AK; Yadav, DK1
Bento, AF; Calixto, JB; Figueiredo, CP; Hara, DB; Mazzuco, TL; Vitor, CE1
Baggio, CH; Freitas, CS; Luiz, AP; Marcon, R; Nascimento, FP; Pizzolatti, MG; Santos, AR; Soldi, C; Werner, MF1
Ahmad, AS; Mansour, AI; Nafady, AM; Ramadan, MA1
Hui, TT; Rao, GX; Wang, WJ; Xue, YM; Zhang, QL1
Bonfill, M; Cusido, RM; Hernandez-Vazquez, L; Moyano, E; Navarro-Ocaña, A; Palazon, J1
Ashidi, JS; Efferth, T; Houghton, PJ; Hylands, PJ1
Ebizuka, Y; Masuda, K; Shibuya, M; Shinozaki, J; Takahata, Y1
Aseff, SG; Calderón, CE; de la Rocha, NE; Guardia, T; Pedernera, AM; Pelzer, LE; Rotelli, AE; Saad, JR; Verrilli, MA1
JEGER, O; RUEGG, R; RUZICKA, L1
RUEGG, R; RUZICKA, L1
Martins, LR; Takahashi, JA1
Akihisa, T; Fukatsu, M; Ichimura, Y; Katoh, N; Kojima, N; Maranz, S; Masters, ET; Suzuki, H1
Chen, Q; Yao, RJ; Zhang, QJ; Zhou, T; Zhu, SH1
Haque, ME; Khondkar, P; Mosaddik, A; Nikkon, F; Salam, KA; Yeasmin, T1
Brito, GA; Carvalho, KM; Chaves, MH; Melo, CM; Morais, TC; Neves, JC; Rao, VS; Santos, FA1
Chin, LC; Ching, J; Chua, TK; Jaya, JM; Koh, HL; Lau, AJ; Pang, YK; Tan, CH1
Cao, YK; Chai, L; Deng, GH; Li, YB; Lin, CZ; Zhang, CX; Zhao, ZX; Zhu, CC1
Guhling, O; Jetter, R; Li, F; Rose, JK; Wang, Z; Yao, R; Yeats, TH1
Hour, TC; Huang, AM; Lee, LY; Lin, CN; Lin, KW; Pu, YS; Tu, HY; Wu, CC; Yang, SC1
Albuquerque, MR; Bandeira, PN; Barros, FW; Costa-Lotufo, LV; de Farias, SS; de Morais, MO; dos Santos, HS; Lemos, TL; Lima, DJ; Meira, AS; Pessoa, Cdo Ó1
Brito, GA; Chaves, MH; Melo, CM; Morais, TC; Rao, VS; Santos, FA; Tomé, AR1
Ching, H; Lin, LW; Lin, WH; Lin, YT; Wen, CL; Wu, CR1
Ching, J; Koh, HL; Lin, HS; Tan, CH1
Dicks, J; Dokarry, M; Etherington, G; Field, B; Geisler, K; Ikeda, K; Inagaki, YS; Mutsukado, Y; Osbourn, A1
Ebersole, JL; Huang, CB; Huang, W; Yoo, JG; Zheng, Y1
Andre, C; Beuning, LL; Brendolise, C; Chagne, D; Eberhard, ED; Greenwood, DR; Wang, M; Yauk, YK1
Bento, AF; Calixto, JB; Meotti, FC; Passos, GF; Paszcuk, AF; Silva, ES; Simão da Silva, KAB1
Arcioni, S; Biazzi, E; Calderini, O; Carelli, M; Graham, N; May, S; Odoardi, M; Panara, F; Piano, E; Porceddu, A; Scaramelli, L; Scotti, C; Tava, A1
Li, MH; Wang, XQ; Wu, G; Zhang, N; Zhou, CJ1
Alves, SH; Athayde, ML; Boligon, AA; Frohlich, JK; Janovik, V; Pozzebon, TV; Schwanz, TG1
Abedy, MK; Maity, N; Mukherjee, PK; Nema, NK; Sarkar, BK1
Ching, J; Koh, HL; Lee, JF; Soh, WL; Tan, CH; Tan, JY; Yang, J; Yap, CW1
Akashi, T; Aoki, T; Fukushima, EO; Mizutani, M; Muranaka, T; Ohnishi, T; Ohyama, K; Saito, K; Sawai, S; Seki, H; Sudo, H1
Arteaga, JF; Barrero, AF; Domingo, V; López Pérez, JL; Peláez, R; Quílez del Moral, JF1
Arruda, AC; Arruda, MS; Batista, EF; Costa, DM; Figueira, BA; Guilhon, GM; Muller, AH; Santos, LS; Secco, RS; Silva, JK; Silva, MN; Souza Filho, AP1
Al-Harrasi, A; Ali, L; Hussain, H; Hussain, J; Rehman, NU1
Biskup, E; Gniadecki, R; Gołębiowski, M; Stepnowski, P; Łojkowska, E1
Chicca, A; Gertsch, J; Marazzi, J1
Aoyama, Y; Fukushima, EO; Kitahama, Y; Kunii, M; Muranaka, T; Seki, H; Yoshida, Y1
Li, J; Li, L; Shang, X; Sun, Z; Wang, R; Zhu, J1
Huang, L; Li, C; Li, J; Liu, B; Wang, H; Ye, H; Zhang, Y1
Arruda, BR; Brito, GA; Chaves, MH; da Silva, AA; de Melo, TS; Frota, JT; Rao, VS; Santos, FA1
Jeya Ananthi, JD; Sathish Kumar, P; Viswanathan, MB1
Buschhaus, C; Jetter, R1
Huttunen, S; Pączkowski, C; Szakiel, A1
Adebajo, AC; Aladesanmi, AJ; Ayoola, MD; Odediran, SA; Schmidt, TJ; Verspohl, EJ1
Chung, LY; Chung, PY; Navaratnam, P2
Bento, AF; Calixto, JB; Claudino, RF; Marcon, R; Matos, I1
Filho, MD; Fingolo, CE; Kaplan, MA; Santos, Tde S1
Fu, M; Kong, QT; Niu, YY; Yu, J1
Chen, Y; Qin, MJ; Wang, GK; Wu, C1
de Oliveira, AR; de Souza, GH; Lopes, NP; Moreira, Fde L; Rodrigues, IV1
Hua, HM; Ji, F; Jiang, C; Jing, WY; Li, ZL1
Bahadori, MB; Hamburger, M; Kaiser, M; Khavasi, HR; Moridi Farimani, M; Nejad Ebrahimi, S; Salehi, P; Sonboli, A; Zimmermann, S1
Muhammad, A; Sirat, HM1
Singh, NK; Singh, VP1
Chen, L; Kang, WY; Wang, W; Wei, JF1
Feng, TT; Zhang, Y; Zhao, Z; Zhou, Y1
Arnason, JT; Cal, V; Cayer, C; Durst, T; Kent, P; Merali, Z; Mullally, M; Poveda Álvarez, L; Puniani, E; Sánchez-Vindas, P1
Amari, K; Hoshino, T; Ito, R; Masukawa, Y; Nakada, C; Nakano, C1
Chen, W; Ma, X; Xu, H; Zhan, R; Zheng, X1
Al Musayeib, NM; Al-Massarani, SM; El Gamal, AA; Ibrahim, SR; Mothana, RA1
Abdul Hamid, R; Awang Hamsin, DE; Khaza'ai, H; Saiful Yazan, L; Yeong, LT1
Broniatowski, M; Flasiński, M; Miśkowiec, P; Zięba, K1
Findlay, KC; Haralampidis, K; Hayashi, K; Honkanen, S; Kemen, AC; Melton, RE; Mugford, ST; Osbourn, A; Rosser, SJ1
Hoshino, T; Ito, R; Takahashi, K; Yamaguchi, Y1
Ahn, YJ; Jang, DS; Jung, JW; Kwon, G; Lee, HE; Lee, Y; Oh, SR; Park, SJ; Ryu, JH; Woo, H1
Ajaghaku, DL; Ilodigwe, EE; Nworu, CS; Okeke, HN; Okoye, FB; Okoye, NN1
Cherng, JY; Shih, MF1
Ashraf, SN; Ercisli, S; Rasool, N; Rizwan, K; Tareen, RB; Zia-Ul-Haq, M; Zubair, M1
Kosma, DK; Molina, I; Razeq, FM; Rowland, O1
Carneiro, SP; de Souza, GH; dos Santos, OD; Lopes, NP; Rodrigues, IV; Seibert, JB1
Jiang, N; Li, C; Lin, Z; Liu, Y; Rasool, A; Sun, H; Sun, X; Zhang, G1
Chen, HH; Gao, Y; Liu, CS; Liu, Y; Wang, LQ; Wen, H1
Helen, A; Krishnan, K; Mathew, LE; Vijayalakshmi, NR1
Broniatowski, M; Flasiński, M; Mastalerz, P1
Goossens, A; Moses, T; Pollier, J; Thevelein, JM1
Aragão, GF; Bandeira, PN; Carneiro, LM; de Lemos, TL; Rota-Junior, AP; Viana, GS1
Arya, PV; Dobhal, MP; Gupta, RS; Sharma, A; Singh, D1
Broniatowski, M; Flasiński, M; Fontaine, P; Wydro, P1
Joshi, SP; Khedkar, VM; Kulkarni, RR; Puranik, VG; Sarkar, D; Shurpali, K1
Cheong, JH; Gao, Q; Hong, E; Jang, DS; Jeon, SJ; Lee, HE; Park, HJ; Park, SJ; Ryu, JH; Shin, CY1
Castillo, DA; Matsuda, SP; Shan, H; Wilson, WK1
Andersen, SB; Augustin, JM; Bak, S; Erthmann, PØ; Fukushima, EO; Hauser, TP; Khakimov, B; Kuzina, V; Muranaka, T; Olsen, CE; Scholtalbers, J; Volpin, H1
Hanaoka, M; Hoshino, T; Kaneko, I; Miyahara, Y; Takahashi, K1
Huang, GQ; Li, B; Lu, RM; Wei, JH; Zhong, ZG1
Al-Rehaily, AJ; Alajmi, MF; Alam, P; Alharbi, H; Basudan, OA; Hussain, A; Siddiqui, NA1
Ikeuchi, S; Ishii, M; Nakahara, T; Nishimura, M1
Moo-Puc, R; Peraza-Sanchez, SR; Quintal-Novelo, C; Torres-Tapia, LW1
Feng, X; Qiu, P; Shan, Y; Wang, M; Wang, QZ; Yin, M; Zhao, YY1
Chen, JW; Chen, Y; Li, X; Zuo, J1
Ji, XY; Li, QR; Wei, Q; Xu, F; Yin, H1
Fukushima, EO; Muranaka, T; Seki, H; Yasumoto, S1
Shi, YP; Wang, CQ; Wang, HT; Xu, H1
Li, SH; Yao, YZ1
Nesi, RT; Pinho, RA; Silveira, PC; Thirupathi, A1
Hoshino, T; Kaneko, I1
Cai, Y; Gong, J; Li, J; Li, S; Liu, Y; Liu, Z; Wang, L; Wang, P; Wei, T; Xiang, F; Xue, Z; Zhao, Z1
Anai, T; Ishimoto, M; Kaga, A; Mukaiyama, K; Ohyama, K; Saito, K; Sawai, S; Sayama, T; Takada, Y; Takagi, K; Tsukamoto, C; Yano, R1
Feng, HX; Fu, Y; Li, JL; Wang, HM; Wu, J; Wu, L; Zhang, HY; Zhang, RJ; Zhao, WM1
Alves, TB; Barbosa, CC; De Lima, GM; Felippe, LG; Furlan, M; Guido, RV; Lopes, NP; Pinheiro, KA; Santos, VA; Souza-Moreira, TM; Valentini, SR; Watanabe, TF; Zanelli, CF1
Dinda, AK; Gupta, YK; Maulik, SK; Prabhakar, P; Reeta, KH1
Hoshino, T; Ito, R; Nakada, C1
Hoshino, T1
Dash, P; Ghosh, G; Panda, P1
Misawa, N; Takemura, M; Tanaka, R1
Batista-Lima, FJ; Carvalho, KMMB; Chaves, MH; da Cruz Fonseca, SG; de Brito, TS; de Carvalho Almeida da Silva, AA; Magalhães, PJC; Nunes, PIG; Rao, VS; Santos, FA; Viana, AFSC1
da Silva Júnior, WF; da Veiga Júnior, VF; de Almeida, PDO; de Azevedo, EP; de Lima, ÁAN; de Menezes, DLB; E Silva, NES; Lima, ES; Pinheiro, JGO1
Chanotiya, CS; Garg, A; Ghosh, S; Misra, RC; Sharma, S1
Chen, D; Deng, J; Liu, J; Sun, H; Wen, X; Xu, F; Zhang, P1
Al-Zghool, HM; Alali, FQ; Albataineh, H; Alzoubi, KH; El-Elimat, T; Khabour, OF; Rawashdeh, NQ1
Chang, CH; Liao, VH; Wei, CC1
Ahmed, S; Cai, Q; Dong, S; Hu, S; Hu, X; Li, X; Wang, X; Yang, T; Zhan, C1
Huo, Y; Li, C; Sun, W; Wang, C; Wang, Y; Zhang, G; Zhou, A; Zhou, X; Zhu, M1
Baijnath, H; Jonnalagadda, SB; Moodley, R; Ogunlaja, OO; Singh, M1
da Silva, OLM; da Silva, UP; Demuner, AJ; Furlani, GM; Varejão, EVV1
Aalami, A; Shirazi, Z; Sohani, MM; Tohidfar, M1
Al-Amri, I; Al-Broumi, M; Al-Harrasi, A; Csuk, R; Hussain, H; Hussain, J; Khan, AL; Rehman, NU1
Csuk, R; Serbian, I1
Adjafre, BL; Aragão, GF; de Moraes, MEA; Nogueira, AO; Oliveira, YIS1
Chang, P; Hong, D; Huo, Y; Li, C; Li, Z; Ren, H; Song, H; Wang, Y; Yu, H; Yu, Y1
Langdon, T; Leveau, A; Melton, RE; Mugford, ST; Osbourn, A; Qiao, X; Rant, JC; Reed, J; Stephenson, MJ; Vickerstaff, R1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1
Araújo, AJ; Barros Pereira, ED; Carvalho, AA; Chaves, MH; Costa Silva, RA; de Melo, KM; de Oliveira, FTB; Gomes Quinderé, AL; Marinho Filho, JDB; Rao, VS; Santos, FA1
Bennett, JW; Bu, LJ; DU, XW; Fang, Y; Han, LT; Huang, F; Mo, GY; Pennerman, KK; Yin, GH1
Fan, J; Li, C; Liu, H; Wang, C; Zhou, X1
Chen, F; Li, W; Liu, DL; Lv, XM; Shao, LD; Wang, W; Wang, WJ1
Chao, EK; Chen, SL; Qian, GT; Su, XY; Su, Y; Sun, MC; Wang, CX; Xue, JP; Zhu, M1
Acharya, RN; Ambasana, PA; Dhalani, JM; Nariya, MB; Nariya, PB; Patel, AS; Shukla, VJ1
Bezerra de Menezes, DL; da Silva Júnior, WF; da Veiga Júnior, VF; de Azevedo, EP; de Oliveira, LC; Koester, LS; Lima, ES; Neves de Lima, ÁA; Oliveira de Almeida, PD1
Anh, NTN; Kiem, PV; Lam, DT; Le, VTT; Minh, PTH; Quan, PM; Tai, BH; Thuy, TTT1
Chen, W; Gu, J; Kuang, Z; Wang, K; Wang, M; Wu, Z; Xu, H; Zhan, R; Zhang, F; Zhang, R1
Ayachit, G; Bhairappanavar, SB; Das, J; Jani, B; Joshi, C; Shaikh, I; Sharma, P; Shukla, L1
Narayanan, AK; Nawada, N; Ranganathan, PR; Rao, DKV1
Abdelaziz, S; El-Fattah, A; Elgaml, SA; Hashish, EA; Shalaby, SI1
Adokoh, CK; Ameyaw, EO; Armah, FA; Ekor, M; Hashimi, RA; Henneh, IT; Huang, B; Musayev, FN; Safo, MK; Zhang, Y1
Bastos, JK; Carvalho, JCAS; Ccana-Ccapatinta, GV; Groppo, M; Mejía, JAA; Tanimoto, MH1
Dale, MP; Johnston, EJ; Moses, T; Rosser, SJ1
Gao, W; Guo, J; Huang, LQ; Lin, HX; Su, P; Wang, J; Wu, XY; Yang, J; Zhao, H1
Chen, Y; Du, CH; Li, MS; Lian, YL; Ma, CG; Pu, YJ; Qin, XM; Tian, HL; Wang, QY; Zhang, FS; Zhang, X1
Kwun, MS; Lee, DG; Lee, HJ1
Alves, APNN; Carvalho, AA; Chaves, MH; Fonseca, SGC; Lima, RP; Nunes, PIG; Oliveira, FTB; Rao, VS; Santos, FA; Silva, RAC; Viana, AFSC; Viana, DA1
Felippe, LG; Furlan, M; Guido, RVC; Mazzeu, BF; Oliveira, AA; Remlinger, M; Souza-Moreira, TM; Valentini, SR; Zanelli, CF1
Xu, J; Xu, W; Zhang, H; Zhang, Q1
Du, MM; Gao, B; Liu, M; Ren, YH; Tao, XY; Wang, FQ; Wei, DZ; Zhang, GG; Zhao, YQ; Zhu, ZT1
Afzal, O; Ahmad, MN; Akhtar, MS; Altamimi, ASA; Athar, F; Beg, MA; Chopra, S; Hussain, A; Imam, MA1
Li, C; Li, X; Liu, X; Shi, C; Wang, Y; Zhang, Y; Zhou, C; Zhu, Y1
Chao, E; Chen, S; Hou, K; Qiu, J; Su, X; Sun, M; Wang, C; Wang, L; Xin, Q; Zhang, X1
Bian, H; Cai, J; Cai, Z; Liu, J1

Reviews

5 review(s) available for oleanolic acid and beta-amyrin

ArticleYear
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Alkaloids; Animals; Biosynthetic Pathways; Drug Discovery; Drugs, Chinese Herbal; Humans; Oxindoles; Uncaria

2021
Saponins in cereals.
    Phytochemistry, 2003, Volume: 62, Issue:1

    Topics: Biological Evolution; Disease Susceptibility; Edible Grain; Molecular Structure; Oleanolic Acid; Poaceae; Saponins; Triterpenes

2003
β-Amyrin biosynthesis: catalytic mechanism and substrate recognition.
    Organic & biomolecular chemistry, 2017, Apr-05, Volume: 15, Issue:14

    Topics: Biocatalysis; Euphorbia; Molecular Conformation; Oleanolic Acid

2017
Pharmacological effects of the isomeric mixture of alpha and beta amyrin from Protium heptaphyllum: a literature review.
    Fundamental & clinical pharmacology, 2019, Volume: 33, Issue:1

    Topics: Animals; Burseraceae; Humans; Oleanolic Acid; Phytotherapy; Resins, Plant; Stereoisomerism

2019
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018

Other Studies

230 other study(ies) available for oleanolic acid and beta-amyrin

ArticleYear
Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Apoptosis; Betulinic Acid; Cell Differentiation; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Molecular Structure; Oxidation-Reduction; Pentacyclic Triterpenes; Pyridinium Compounds; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2002
Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
    Journal of natural products, 2007, Volume: 70, Issue:8

    Topics: Animals; Benin; Cell Line, Tumor; Molecular Structure; Plant Leaves; Plants, Medicinal; Sterols; Stigmasterol; Structure-Activity Relationship; Strychnos; Triterpenes; Trypanocidal Agents; Trypanosoma brucei brucei

2007
Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis.
    Bioorganic & medicinal chemistry letters, 2016, May-01, Volume: 26, Issue:9

    Topics: Drug Evaluation, Preclinical; Plant Extracts; Plants, Medicinal; Trichomonas vaginalis

2016
Camellianols A-G, Barrigenol-like Triterpenoids with PTP1B Inhibitory Effects from the Endangered Ornamental Plant Camellia crapnelliana.
    Journal of natural products, 2017, 11-22, Volume: 80, Issue:11

    Topics: Camellia; Cyclohexanones; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Components, Aerial; Plant Leaves; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Triterpenes

2017
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
Antilipoxygenase activity of amyrin triterpenes.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 78, Issue:3

    Topics: Female; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Oleanolic Acid; Triterpenes

1992
An antidepressant principle of Lobelia inflata L. (Campanulaceae).
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:7

    Topics: Animals; Antidepressive Agents; Imipramine; Male; Mice; Mice, Inbred Strains; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Triterpenes

1992
[Chemical constituents of Vaccinium scopulorum W.W. Smith].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:4

    Topics: Drugs, Chinese Herbal; Oleanolic Acid; Triterpenes; Ursolic Acid

1992
[Constituents of Marsdenia officinalis Tsiang].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1991, Volume: 16, Issue:9

    Topics: Drugs, Chinese Herbal; Oleanolic Acid; Triterpenes

1991
[Studies on the chemical constituents of Zanthoxylum planispinum Sieb. et Zucc].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:6

    Topics: Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Dioxoles; Drugs, Chinese Herbal; Lignans; Oleanolic Acid; Triterpenes

1988
The sterols of growth and stationary phases of Aspergillus nidulans cultures.
    Journal of general microbiology, 1985, Volume: 131, Issue:2

    Topics: Aspergillus nidulans; Chromatography, Gas; Ergosterol; Lanosterol; Oleanolic Acid; Sterols; Triterpenes

1985
Studies on the labelling of terpenoids in shoots and cells or protoplasts from Calendula officinalis leaves.
    Acta biochimica Polonica, 1982, Volume: 29, Issue:1-2

    Topics: Acetates; Bicarbonates; Carbon Radioisotopes; Oleanolic Acid; Plant Cells; Plants; Protoplasts; Sterols; Terpenes; Triterpenes

1982
Isolation of beta-amyrin from the fungus Aspergillus nidulans.
    Journal of general microbiology, 1983, Volume: 129, Issue:3

    Topics: Oleanolic Acid; Triterpenes

1983
Effect of alpha-amyrin palmitate on adjuvant arthritis.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:1

    Topics: Animals; Arthritis, Experimental; Cartilage; Drugs, Chinese Herbal; Foot; Freund's Adjuvant; Granulocytes; Hyaluronic Acid; Joints; Male; Oleanolic Acid; Rats; Rats, Wistar; Triterpenes

1994
Antiarthritic mechanisms of amyrin triterpenes.
    Research communications in molecular pathology and pharmacology, 1994, Volume: 85, Issue:1

    Topics: Animals; Arthritis, Experimental; Cell Division; Collagenases; Esters; Female; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Methotrexate; Neutrophils; Oleanolic Acid; Rats; Rats, Wistar; Triterpenes; Tumor Cells, Cultured

1994
[Studies on chemical constituents of Marsdenia oreophila].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1993, Volume: 18, Issue:4

    Topics: Drugs, Chinese Herbal; Oleanolic Acid; Triterpenes

1993
Beta-amyrin synthase--cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants.
    European journal of biochemistry, 1998, Aug-15, Volume: 256, Issue:1

    Topics: Amino Acid Sequence; Cloning, Molecular; Conserved Sequence; DNA Primers; Intramolecular Transferases; Models, Chemical; Molecular Sequence Data; Oleanolic Acid; Panax; Plants, Medicinal; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Squalene; Triterpenes

1998
Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling.
    European journal of biochemistry, 1998, Sep-01, Volume: 256, Issue:2

    Topics: Affinity Labels; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Azo Compounds; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Calcium; Humans; Leukocytes; Lipoxygenase Inhibitors; Molecular Structure; Oleanolic Acid; Quinolines; Triterpenes

1998
Acetyl-11-keto-beta-boswellic acid induces apoptosis in HL-60 and CCRF-CEM cells and inhibits topoisomerase I.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Division; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; HL-60 Cells; Humans; Isoenzymes; Leukemia, T-Cell; Lipoxygenase Inhibitors; Oleanolic Acid; Rats; RNA, Messenger; Topoisomerase I Inhibitors; Triterpenes; Tumor Cells, Cultured

1999
Selective inhibition of eukaryote protein kinases by anti-inflammatory triterpenoids.
    Planta medica, 1999, Volume: 65, Issue:1

    Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Kinetics; Molecular Sequence Data; Oleanolic Acid; Pentacyclic Triterpenes; Protein Kinase Inhibitors; Rats; Triterpenes

1999
Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new alpha-amyrin-producing enzyme is a multifunctional triterpene synthase.
    European journal of biochemistry, 2000, Volume: 267, Issue:12

    Topics: Amino Acid Sequence; Cloning, Molecular; Conserved Sequence; DNA Primers; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; Pisum sativum; Polymerase Chain Reaction; Seeds; Sequence Homology, Amino Acid; Triterpenes; Yeasts

2000
[Chemical constituents of Begonia evansiana Andr].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:5

    Topics: Drugs, Chinese Herbal; Flavonoids; Glucosides; Magnoliopsida; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Sitosterols; Stigmasterol; Triterpenes

1997
Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana.
    Plant molecular biology, 2001, Volume: 45, Issue:1

    Topics: Amino Acid Sequence; Arabidopsis; Cloning, Molecular; DNA, Complementary; DNA, Recombinant; Gene Expression Regulation, Enzymologic; Genes, Plant; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; Pentacyclic Triterpenes; Phylogeny; Plasmids; Saccharomyces cerevisiae; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Triterpenes

2001
Pregnene derivatives from Solenostemma argel leaves.
    Phytochemistry, 2001, Volume: 57, Issue:4

    Topics: Africa, Northern; Biological Factors; Medicine, Traditional; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Sitosterols; Triterpenes

2001
Eclalbatin, a triterpene saponin from Eclipta alba.
    Journal of Asian natural products research, 2001, Volume: 3, Issue:3

    Topics: Asteraceae; Chromatography, Thin Layer; India; Mass Spectrometry; Medicine, Traditional; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Saponins; Spectrophotometry, Infrared; Triterpenes; Ursolic Acid

2001
The effect of aromatization on the isotopic compositions of hydrocarbons during early diagenesis.
    Organic geochemistry, 1994, Volume: 21, Issue:10-11

    Topics: Carbon Isotopes; Environmental Microbiology; Eukaryota; Geologic Sediments; Germany; Marine Biology; Oleanolic Acid; Paleontology; Plants; Polycyclic Aromatic Hydrocarbons; Triterpenes

1994
[Chemical constituents of Cichorium intybus L].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:11

    Topics: Cichorium intybus; Drugs, Chinese Herbal; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Sitosterols; Triterpenes

1998
Phytochemical and antimicrobial studies on Drynaria quercifolia.
    Fitoterapia, 2001, Volume: 72, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Microbial Sensitivity Tests; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Sitosterols; Triterpenes

2001
Phytosterol content in American ginseng seed oil.
    Journal of agricultural and food chemistry, 2002, Feb-13, Volume: 50, Issue:4

    Topics: Cholesterol; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Oleanolic Acid; Panax; Phytosterols; Plant Oils; Seeds; Sitosterols; Squalene; Stigmasterol; Triterpenes

2002
Toxin clues to beetle relationships.
    Current biology : CB, 2002, Feb-19, Volume: 12, Issue:4

    Topics: Adaptation, Biological; Animals; Coleoptera; Diet; Evolution, Molecular; Host-Parasite Interactions; Oleanolic Acid; Pigmentation; Saponins; Toxins, Biological; Triterpenes

2002
[Studies on chemical constituents of Tinospora hainanesis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:5

    Topics: Berberine Alkaloids; Drugs, Chinese Herbal; Molecular Structure; Oleanolic Acid; Plant Shoots; Tinospora; Triterpenes

1998
Quinovic acid glycosides from Mitragyna stipulosa--first examples of natural inhibitors of snake venom phosphodiesterase I.
    Natural product letters, 2002, Volume: 16, Issue:6

    Topics: Cameroon; Glucosides; Mitragyna; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Phosphodiesterase Inhibitors; Plant Bark; Plant Extracts; Plants, Medicinal; Snake Venoms; Stereoisomerism; Triterpenes

2002
A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula.
    The Plant journal : for cell and molecular biology, 2002, Volume: 32, Issue:6

    Topics: Acetates; Amino Acid Sequence; Carbohydrate Sequence; Cells, Cultured; Cyclopentanes; Escherichia coli; Expressed Sequence Tags; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genomics; Intramolecular Transferases; Medicago; Molecular Sequence Data; Oleanolic Acid; Oxygenases; Oxylipins; Phylogeny; Phytosterols; Saponins; Signal Transduction; Squalene Monooxygenase; Triterpenes

2002
[Studies on the chemical constituents of Quercus mongolica].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 1998, Volume: 21, Issue:4

    Topics: Fatty Alcohols; Gallic Acid; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Quercus; Sitosterols; Spectrophotometry, Ultraviolet; Triterpenes

1998
Irritant potential of some constituents from the seeds of Caesalpinia bonducella (L.) fleming.
    Journal of Asian natural products research, 2003, Volume: 5, Issue:1

    Topics: Animals; Caesalpinia; Dose-Response Relationship, Drug; Inflammation; Irritants; Mice; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Seeds; Triterpenes

2003
[Studies on chemical constituents in herba of Lysimachia davurica].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002, Volume: 27, Issue:4

    Topics: Cerebrosides; Oleanolic Acid; Plants, Medicinal; Primulaceae; Triterpenes

2002
[Investigation on chemistry of linden leaves; presence of beta-amyrin].
    Acta pharmaceutica Jugoslavica, 1955, Volume: 5, Issue:1

    Topics: Alcohols; Oleanolic Acid; Plant Leaves; Resins, Plant; Resins, Synthetic; Tilia

1955
The biosynthesis of beta-amyrin and beta-sitosterol in germinating seeds of Pisum sativum.
    Biochemistry, 1962, May-25, Volume: 1

    Topics: Lipid Metabolism; Oleanolic Acid; Pisum sativum; Seeds; Sitosterols; Sterols

1962
SQUALENE IN PISUM SATIVUM. ITS CYCLIZATION TO BETA-AMYRIN AND LABELING PATTERN.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Carbon Isotopes; Chromatography; Cyclization; Metabolism; Oleanolic Acid; Pisum sativum; Plants; Research; Squalene; Terpenes

1965
Recycling plant wax constituents for chemical defense: hemi-biosynthesis of triterpene saponins from beta-amyrin in a leaf beetle.
    Die Naturwissenschaften, 2003, Volume: 90, Issue:11

    Topics: Animals; Asteraceae; Coleoptera; Oleanolic Acid; Plant Leaves; Saponins; Triterpenes; Waxes

2003
[Studies on chemical constituents from the bark of Morus macroura].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:2

    Topics: Morus; Oleanolic Acid; Organic Chemicals; Plant Bark; Plant Extracts; Plants, Medicinal

2003
Isolation and structure of gustastatin from the Brazilian nut tree Gustavia hexapetala.
    Journal of natural products, 2004, Volume: 67, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Brazil; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Lecythidaceae; Leukemia P388; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Phenols; Plants, Medicinal; Trees; Triterpenes

2004
Pentacyclic triterpenoids, alpha,beta-amyrins, suppress the scratching behavior in a mouse model of pruritus.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cell Degranulation; Cyproheptadine; Dextrans; Endorphins; Female; Histamine H1 Antagonists; Ketotifen; Mast Cells; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Oleanolic Acid; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Pruritus; Receptors, Opioid, mu

2004
Gastroprotective effect of the mixture of alpha- and beta-amyrin from Protium heptaphyllum: role of capsaicin-sensitive primary afferent neurons.
    Planta medica, 2004, Volume: 70, Issue:8

    Topics: Administration, Oral; Animals; Burseraceae; Capsaicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethanol; Gastritis; Gastrointestinal Agents; Male; Mice; Neurons, Afferent; Oleanolic Acid; Phytotherapy; Wood

2004
Antimicrobial activity of some pentacyclic triterpenes and their synthesized 3-O-lipophilic chains.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:10

    Topics: Anti-Bacterial Agents; Bacteria; Diospyros; Esterification; Fatty Acids; Microbial Sensitivity Tests; Molecular Weight; Oleanolic Acid; Plant Extracts; Plant Leaves; Triterpenes; Ursolic Acid

2004
Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Bradykinin; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dose-Response Relationship, Drug; Drug Combinations; Formaldehyde; Glutamic Acid; Heart; Male; Mice; Oleanolic Acid; Pain; Pain Measurement; Peripheral Nervous System; Physical Stimulation; Protein Kinase C; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Spinal Cord; Stimulation, Chemical; Triterpenes

2005
Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene.
    European journal of pharmacology, 2005, Jan-10, Volume: 507, Issue:1-3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burseraceae; Dose-Response Relationship, Drug; Edema; Ether; Male; Mice; Oleanolic Acid; Plant Bark; Plant Extracts; Triterpenes

2005
Protective effect of alpha- and beta-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice.
    Journal of ethnopharmacology, 2005, Apr-08, Volume: 98, Issue:1-2

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Burseraceae; Disease Models, Animal; Drug Administration Schedule; Drug Synergism; Glutathione; Injections, Intraperitoneal; Liver Failure, Acute; Male; Mice; Necrosis; Oleanolic Acid; Pentobarbital; Phytotherapy; Plant Bark; Plants, Medicinal; Protective Agents; Resins, Plant; Sleep; Triterpenes

2005
DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside.
    Natural product research, 2005, Volume: 19, Issue:5

    Topics: Ajuga; DNA Damage; Iridoids; Oleanolic Acid; Plant Extracts; Sitosterols; Sterols; Triterpenes; Ursolic Acid

2005
Attenuation of capsaicin-induced acute and visceral nociceptive pain by alpha- and beta-amyrin, a triterpene mixture isolated from Protium heptaphyllum resin in mice.
    Life sciences, 2005, Oct-21, Volume: 77, Issue:23

    Topics: Administration, Oral; Analgesics; Animals; Behavior, Animal; Burseraceae; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Hypothermia; Mice; Motor Activity; Oleanolic Acid; Pain; Postural Balance; Resins, Plant; Sleep

2005
[Studies on the chemical constituents from the leaf of Liquidambar formosana Hance].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:4

    Topics: Chromatography, High Pressure Liquid; Liquidambar; Methanol; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Sitosterols; Triterpenes

2005
Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation.
    Journal of lipid research, 2005, Volume: 46, Issue:11

    Topics: Antioxidants; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Caco-2 Cells; Carotenoids; Cholesterol; Cholesterol, LDL; DNA-Binding Proteins; Humans; Hydrocarbons; Intestinal Absorption; Intestines; Liver X Receptors; Micelles; Models, Chemical; Oleanolic Acid; Orphan Nuclear Receptors; Pentacyclic Triterpenes; Peptides; Phytosterols; Plant Extracts; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sitosterols; Sterol Regulatory Element Binding Protein 2; Triterpenes

2005
Surface composition of myrmecophilic plants: cuticular wax and glandular trichomes on leaves of Macaranga tanarius.
    Journal of chemical ecology, 2005, Volume: 31, Issue:10

    Topics: Acetates; Alcohols; Aldehydes; Animals; Euphorbiaceae; Fatty Acids; Insecta; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Terpenes; Triterpenes; Waxes

2005
Identification of biologically active triterpenes and sterols present in hexane extracts from Miconia species using high-resolution gas chromatography.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:8

    Topics: Chromatography, Gas; Hexanes; Melastomataceae; Oleanolic Acid; Phytosterols; Plant Components, Aerial; Plant Extracts; Sitosterols; Triterpenes

2006
Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice.
    Planta medica, 2006, Volume: 72, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Burseraceae; Male; Mice; Molecular Structure; Nociceptors; Oleanolic Acid; Pain Measurement; Plant Extracts; Resins, Plant; Ruthenium Red; Triterpenes; TRPV Cation Channels; Viscera; Yohimbine

2006
[Studies on the chemical constituents in root of Coleus forskohlii].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:22

    Topics: Betulinic Acid; Coleus; Diterpenes; Oleanolic Acid; Pentacyclic Triterpenes; Plant Roots; Plants, Medicinal; Triterpenes

2005
Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay.
    The FEBS journal, 2006, Volume: 273, Issue:5

    Topics: Base Sequence; Cytochrome P-450 Enzyme System; DNA, Complementary; DNA, Plant; Expressed Sequence Tags; Gas Chromatography-Mass Spectrometry; Gene Expression; Genes, Plant; Glycine max; Intramolecular Transferases; Oleanolic Acid; Plants; Recombinant Proteins; Saccharomyces cerevisiae

2006
[Chemical constituents from roots of Ficus hirta].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:2

    Topics: Ficus; Ficusin; Flavones; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sitosterols; Stigmasterol

2006
[Studies on constituents from root and stem of Ervatamia hainanensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:14

    Topics: Apocynaceae; Ergosterol; Oleanolic Acid; Plant Roots; Plant Stems; Plants, Medicinal; Triterpenes

2006
A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Burseraceae; Diazepam; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Imipramine; Mice; Oleanolic Acid; Plant Preparations; Reserpine

2006
[Studies on the chemical constituents of hypogeal part from Limonium bicolor].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:11

    Topics: Benzene Derivatives; Gallic Acid; Gas Chromatography-Mass Spectrometry; Luteolin; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Plumbaginaceae; Quercetin; Sitosterols; Spectrophotometry, Ultraviolet; Styrene

2006
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
    European journal of pharmacology, 2007, Mar-22, Volume: 559, Issue:2-3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; NF-kappa B; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Skin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA

2007
Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase.
    Journal of the American Chemical Society, 2007, Feb-07, Volume: 129, Issue:5

    Topics: Arabidopsis; Carbon; Catalysis; Cations; Intramolecular Transferases; Magnetic Resonance Spectroscopy; Models, Chemical; Oleanolic Acid; Spectrometry, Mass, Electrospray Ionization; Triterpenes

2007
Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.
    Neurochemical research, 2007, Volume: 32, Issue:11

    Topics: Animals; Brain; Diterpenes; Flavanones; Genistein; Glutamic Acid; Oleanolic Acid; Plant Extracts; Rats; Rats, Wistar; Sesquiterpenes; Synaptic Transmission; Synaptosomes; Triterpenes

2007
Antifungal activity of the amyrin derivatives and in vitro inhibition of Candida albicans adhesion to human epithelial cells.
    Letters in applied microbiology, 2007, Volume: 45, Issue:2

    Topics: Adult; Antifungal Agents; Candida albicans; Cell Adhesion; Cells, Cultured; Epithelial Cells; Humans; Microbial Sensitivity Tests; Mouth Mucosa; Oleanolic Acid

2007
Determination of three major triterpenoids in epicuticular wax of cabbage (Brassica oleracea L.) by high-performance liquid chromatography with UV and mass spectrometric detection.
    Journal of chromatography. A, 2007, Sep-14, Volume: 1164, Issue:1-2

    Topics: Brassica; Chromatography, High Pressure Liquid; Mass Spectrometry; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Reproducibility of Results; Spectrophotometry, Ultraviolet; Triterpenes; Waxes

2007
[Study on chemical constituents in rhigome of Ervatamia hainanensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:13

    Topics: Apocynaceae; Chromatography, Gel; Ibogaine; Oleanolic Acid; Plants, Medicinal; Rhizome

2007
Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis.
    Chemical & pharmaceutical bulletin, 2007, Volume: 55, Issue:10

    Topics: Arabidopsis; Chromatography, Gas; Deuterium; Genes, Plant; HMGB1 Protein; HMGB2 Protein; Hydroxymethylglutaryl CoA Reductases; Mevalonic Acid; Mutation; Oleanolic Acid; Pentacyclic Triterpenes; Phenotype; Sterols; Triterpenes

2007
[Studies on chemical constituents of Helwingia chinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:14

    Topics: Cinnamates; Cornaceae; Oleanolic Acid; Plants, Medicinal; Triterpenes

2007
[Studies on chemical constituentsfrom leaves of Acer truncatum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:15

    Topics: Acer; Gallic Acid; Kaempferols; Oleanolic Acid; Plant Leaves; Plants, Medicinal

2007
Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis.
    Inflammopharmacology, 2008, Volume: 16, Issue:1

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Inflammatory Agents; Burseraceae; Dexamethasone; Diclofenac; Disease Models, Animal; Gingiva; Gingivitis; Isomerism; Male; Molecular Structure; Neutrophil Infiltration; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Periodontitis; Peroxidase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2008
21beta-Hydroxy-oleanane-type triterpenes from Hippocratea excelsa.
    Phytochemistry, 2008, Volume: 69, Issue:4

    Topics: Hippocrateaceae; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Triterpenes; Ursolic Acid

2008
Synthetic derivatives of the alpha- and beta-amyrin triterpenes and their antinociceptive properties.
    Bioorganic & medicinal chemistry, 2008, Mar-15, Volume: 16, Issue:6

    Topics: Analgesics; Animals; Disease Models, Animal; Mice; Molecular Structure; Oleanolic Acid; Pain; Structure-Activity Relationship; Triterpenes

2008
Antinoceptive effect of triterpenoid alpha,beta-amyrin in rats on orofacial pain induced by formalin and capsaicin.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:8

    Topics: Analgesics; Animals; Burseraceae; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Facial Pain; Formaldehyde; Male; Molecular Structure; Oleanolic Acid; Phytotherapy; Rats; Rats, Wistar

2008
Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56, Issue:12

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclophosphamide; Cystitis; Edema; Glyburide; KATP Channels; Male; Mice; Oleanolic Acid; Pain; Receptors, Neurokinin-1; TRPV Cation Channels; Urinary Bladder

2007
Analgesic and anti-inflammatory activities of the isomeric mixture of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) march.
    Journal of herbal pharmacotherapy, 2007, Volume: 7, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Mice; Oleanolic Acid; Pain; Pain Measurement; Phytotherapy

2007
The isolation of beta-amyrin and a fatty acid of high molecular weight from Solidago leavenworthii T. and G.
    Journal of the American Chemical Society, 1948, Volume: 70, Issue:2

    Topics: Fatty Acids; Molecular Weight; Oleanolic Acid; Solidago

1948
Synthesis of alpha-amyrin derivatives and their in vivo antihyperglycemic activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Oleanolic Acid; Rats; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Streptozocin

2009
Identification of a product specific beta-amyrin synthase from Arabidopsis thaliana.
    Plant physiology and biochemistry : PPB, 2009, Volume: 47, Issue:1

    Topics: Amino Acid Sequence; Arabidopsis; DNA, Complementary; Evolution, Molecular; Intramolecular Transferases; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oleanolic Acid; Phylogeny; Saccharomyces cerevisiae; Sequence Alignment; Triterpenes

2009
[Studies on the constituents from the herba of Erigeron acer].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:9

    Topics: Caffeic Acids; Chromatography, Thin Layer; Erigeron; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Quercetin

2008
Association of early experience with neurodegeneration in aged primates.
    Neurobiology of aging, 2011, Volume: 32, Issue:1

    Topics: Aging; Animals; Disease Models, Animal; Environment; Macaca mulatta; Neocortex; Neurodegenerative Diseases; Oleanolic Acid; Synaptophysin

2011
In vitro evaluation of the antiplasmodial activity of Dendropanax morbifera against chloroquine-sensitive strains of Plasmodium falciparum.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:11

    Topics: Antimalarials; Araliaceae; Cell Line, Tumor; Chloroquine; Humans; Inhibitory Concentration 50; Molecular Structure; Oleanolic Acid; Plant Extracts; Plasmodium falciparum; Saponins; Triterpenes

2009
Antihyperglycaemic activity of alpha-amyrin acetate in rats and db/db mice.
    Natural product research, 2009, Volume: 23, Issue:9

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Ficus; Glucose Tolerance Test; Hypoglycemic Agents; Lipids; Male; Mice; Molecular Structure; Oleanolic Acid; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar

2009
Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis.
    British journal of pharmacology, 2009, Volume: 157, Issue:6

    Topics: Animals; Colitis; Disease Models, Animal; Drug Therapy, Combination; Male; Mice; Oleanolic Acid; Pentacyclic Triterpenes; Trinitrobenzenesulfonic Acid

2009
Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate.
    Brain research, 2009, Oct-27, Volume: 1295

    Topics: Acetic Acid; Analgesics; Analysis of Variance; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Male; Mice; Motor Activity; Neurons; Oleanolic Acid; Opioid Peptides; Pain; Pain Measurement; Physical Stimulation; Protein Kinase C; Psychomotor Performance; Rats; Rats, Wistar; Serotonin; Signal Transduction; TRPV Cation Channels

2009
Chemical composition of the stem bark and leaves of Ficus pandurata Hance.
    Natural product research, 2009, Volume: 23, Issue:13

    Topics: Betulinic Acid; Ficus; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Plant Leaves; Sitosterols; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stigmasterol; Triterpenes; Ursolic Acid

2009
[Studies on the chemical constituents of the leaves of Polygonum multiflorum].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:6

    Topics: Apigenin; Emodin; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Polygonum; Rutin; Sitosterols

2009
Conversion of alpha-amyrin into centellosides by plant cell cultures of Centella asiatica.
    Biotechnology letters, 2010, Volume: 32, Issue:2

    Topics: Cell Culture Techniques; Cell Proliferation; Cell Survival; Centella; Monoglycerides; Oleanolic Acid

2010
Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves.
    Journal of ethnopharmacology, 2010, Mar-24, Volume: 128, Issue:2

    Topics: Cajanus; Cell Line, Tumor; Data Collection; Ethnobotany; Ethnopharmacology; Flavanones; Humans; Male; Neoplasms; Nigeria; Oleanolic Acid; Plant Leaves; Plants; Plants, Medicinal; Sitosterols

2010
Molecular evolution of fern squalene cyclases.
    Chembiochem : a European journal of chemical biology, 2010, Feb-15, Volume: 11, Issue:3

    Topics: Evolution, Molecular; Ferns; Lyases; Molecular Sequence Data; Oleanolic Acid; Phylogeny; Triterpenes

2010
Anti-inflammatory effect of Acacia visco extracts in animal models.
    Inflammopharmacology, 2010, Volume: 18, Issue:5

    Topics: Acacia; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Female; Granuloma; Male; Mice; Oleanolic Acid; Pentacyclic Triterpenes; Phospholipases A2; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar

2010
Knowledge of the triterpenes: degradation of the alpha-amyrin in the rings D and E to beta-methyl-tricarballylic acid.
    Helvetica chimica acta, 1947, Volume: 30, Issue:5

    Topics: Oleanolic Acid

1947
To know the triterpenes; A new ring opening in the alpha-amyrin range.
    Helvetica chimica acta, 1947, Feb-01, Volume: 30, Issue:1

    Topics: Oleanolic Acid; Terpenes

1947
Rearrangement and oxidation of beta-amyrin promoted by growing cells of Lecanicillium muscarinium.
    Natural product research, 2010, Volume: 24, Issue:8

    Topics: Biotransformation; Mitosporic Fungi; Molecular Structure; Oleanolic Acid; Oxidation-Reduction

2010
Triterpene alcohol and fatty acid composition of shea nuts from seven African countries.
    Journal of oleo science, 2010, Volume: 59, Issue:7

    Topics: Africa; Fatty Acids; Imidazoles; Nuts; Oleanolic Acid; Oleic Acid; Pentacyclic Triterpenes; Plant Oils; Sapotaceae; Stearic Acids; Temperature; Triterpenes

2010
[Study on the chemical constituents of Dichrocephala integrifolia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:1

    Topics: Asteraceae; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Stearic Acids

2010
Mosquitocidal triterpenes from the stem of Duranta repens.
    Pharmaceutical biology, 2010, Volume: 48, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Culex; Insecticide Resistance; Insecticides; Larva; Lethal Dose 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Mosquito Control; Oleanolic Acid; Plant Extracts; Plant Stems; Reproducibility of Results; Spectrophotometry, Infrared; Time Factors; Triterpenes; Verbenaceae

2010
alpha,beta-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats.
    World journal of gastroenterology, 2010, Sep-14, Volume: 16, Issue:34

    Topics: Acute Disease; Animals; Arginine; Interleukin-6; Male; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Oleanolic Acid; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2010
Beta-amyrin from Ardisia elliptica Thunb. is more potent than aspirin in inhibiting collagen-induced platelet aggregation.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:3

    Topics: Animals; Ardisia; Aspirin; Collagen; Dose-Response Relationship, Drug; Male; Oleanolic Acid; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits

2010
[Studies on the chemical constituents of Callicarpa kochiana].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:6

    Topics: Callicarpa; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Leaves; Plant Stems; Plants, Medicinal; Spectrophotometry, Ultraviolet; Triterpenes; Ursolic Acid

2010
Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids.
    Plant physiology, 2011, Volume: 155, Issue:1

    Topics: Alleles; Amino Acid Sequence; Cloning, Molecular; Cyclization; DNA, Complementary; Fruit; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; Phylogeny; Plant Epidermis; Plant Leaves; Plant Proteins; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Solanum lycopersicum; Triterpenes

2011
Xanthine oxidase inhibitory triterpenoid and phloroglucinol from guttiferaceous plants inhibit growth and induced apoptosis in human NTUB1 cells through a ROS-dependent mechanism.
    Journal of agricultural and food chemistry, 2011, Jan-12, Volume: 59, Issue:1

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Down-Regulation; Enzyme Inhibitors; Garcinia; Humans; Oleanolic Acid; Phloroglucinol; Plant Extracts; Reactive Oxygen Species; Urinary Bladder Neoplasms; Xanthine Oxidase

2011
Amyrin esters induce cell death by apoptosis in HL-60 leukemia cells.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Burseraceae; Caspase 3; Cell Cycle; Cell Death; Cell Line, Tumor; HL-60 Cells; Humans; Leukocytes, Mononuclear; Molecular Structure; Oleanolic Acid; Plant Preparations

2011
Anti-inflammatory effect of α,β-amyrin, a triterpene from Protium heptaphyllum, on cerulein-induced acute pancreatitis in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:7

    Topics: Amylases; Animals; Anti-Inflammatory Agents; Burseraceae; Ceruletide; Disease Models, Animal; Immunosuppressive Agents; Interleukin-6; Male; Mice; Nitric Oxide Synthase Type II; Oleanolic Acid; Pancreatitis; Peroxidase; Random Allocation; Thalidomide; Tumor Necrosis Factor-alpha

2011
Analgesic and anti-inflammatory property of the methanol extract from Ligustrum morrisonense leaves in rodents.
    The American journal of Chinese medicine, 2011, Volume: 39, Issue:2

    Topics: Abdomen; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capillary Permeability; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Ligustrum; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Pain; Pentacyclic Triterpenes; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Triterpenes

2011
Quantification of α- and β-amyrin in rat plasma by gas chromatography-mass spectrometry: application to preclinical pharmacokinetic study.
    Journal of mass spectrometry : JMS, 2011, Volume: 46, Issue:5

    Topics: Administration, Oral; Animals; Area Under Curve; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Drug Stability; Gas Chromatography-Mass Spectrometry; Injections, Intravenous; Linear Models; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity

2011
Investigation of the potential for triterpene synthesis in rice through genome mining and metabolic engineering.
    The New phytologist, 2011, Volume: 191, Issue:2

    Topics: Amino Acid Sequence; Biological Evolution; Genome, Plant; Intramolecular Transferases; Molecular Sequence Annotation; Multigene Family; Oleanolic Acid; Oryza; Phylogeny; Plant Proteins; Plants, Genetically Modified; Poaceae; Sequence Alignment; Squalene; Sterol 14-Demethylase; Triterpenes

2011
Antibacterial compounds from Siraitia grosvenorii leaves.
    Natural product research, 2011, Volume: 25, Issue:9

    Topics: Aggregatibacter actinomycetemcomitans; Anthraquinones; Anti-Bacterial Agents; Candida albicans; Cucurbitaceae; Drugs, Chinese Herbal; Fusobacterium nucleatum; Glucosyltransferases; Hydroxybenzoates; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Plant Leaves; Seeds; Streptococcus mutans

2011
An unusual plant triterpene synthase with predominant α-amyrin-producing activity identified by characterizing oxidosqualene cyclases from Malus × domestica.
    The FEBS journal, 2011, Volume: 278, Issue:14

    Topics: Amino Acid Motifs; Amino Acid Sequence; Expressed Sequence Tags; Fruit; Gene Expression Profiling; Gene Expression Regulation, Plant; Intramolecular Transferases; Isoenzymes; Malus; Molecular Sequence Data; Oleanolic Acid; Phylogeny; Plant Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Triterpenes

2011
Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice.
    Pain, 2011, Volume: 152, Issue:8

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Area Under Curve; Body Weight; Cyclohexanols; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edema; Enzyme-Linked Immunosorbent Assay; Freezing Reaction, Cataleptic; Hyperalgesia; Inflammation; Locomotion; Male; Mice; Neuralgia; Oleanolic Acid; Oligodeoxyribonucleotides, Antisense; Pain Threshold; Pentacyclic Triterpenes; Peroxidase; Protein Binding; Rats; Rats, Wistar; Receptors, Cannabinoid; Tritium

2011
Medicago truncatula CYP716A12 is a multifunctional oxidase involved in the biosynthesis of hemolytic saponins.
    The Plant cell, 2011, Volume: 23, Issue:8

    Topics: Animals; Base Sequence; Cattle; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glycosylation; Hemolytic Agents; Humans; Medicago truncatula; Molecular Sequence Data; Mutation; Oleanolic Acid; Oxidation-Reduction; Plant Leaves; Plant Proteins; Plant Roots; Plants, Genetically Modified; Saccharomyces cerevisiae; Sapogenins; Saponins; Transcriptome

2011
[Studies on the chemical constituents of Artemisia lavandulaefolia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:2

    Topics: Artemisia; Flavones; Molecular Structure; Oleanolic Acid; Plant Components, Aerial; Plants, Medicinal; Sitosterols; Triterpenes; Ursolic Acid

2011
Isolation and chromatographic analysis of bioactive triterpenoids from the bark extract of Cariniana domestica (Mart) Miers.
    Natural product research, 2012, Volume: 26, Issue:1

    Topics: Antifungal Agents; Antioxidants; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Lecythidaceae; Magnetic Resonance Spectroscopy; Methylene Chloride; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Saccharomyces cerevisiae; Sitosterols; Stigmasterol; Triterpenes

2012
Exploring Tagetes erecta Linn flower for the elastase, hyaluronidase and MMP-1 inhibitory activity.
    Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Enzyme Inhibitors; Flowers; Gallic Acid; Humans; Hyaluronoglucosaminidase; Leukocyte Elastase; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Methanol; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Protease Inhibitors; Skin Aging; Solvents; Tagetes

2011
Identification of active compounds from medicinal plant extracts using gas chromatography-mass spectrometry and multivariate data analysis.
    Journal of separation science, 2012, Volume: 35, Issue:1

    Topics: Ardisia; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Multivariate Analysis; Oleanolic Acid; Plant Extracts; Plant Leaves; Plants, Medicinal; Platelet Aggregation

2012
Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin.
    The Plant cell, 2011, Volume: 23, Issue:11

    Topics: Cytochrome P-450 Enzyme System; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Medicago truncatula; Molecular Sequence Data; Oleanolic Acid; Triterpenes; Yeasts

2011
Total synthesis of (+)-seco-C-oleanane via stepwise controlled radical cascade cyclization.
    The Journal of organic chemistry, 2012, Jan-06, Volume: 77, Issue:1

    Topics: Biological Products; Catalysis; Cyclization; Molecular Structure; Oleanolic Acid; Quantum Theory; Stereoisomerism; Triterpenes

2012
Chemical constituents and allelopathic and antioxidant activities of Alchorneopsis floribunda Müll. Arg. (Euphorbiaceae).
    Natural product research, 2013, Volume: 27, Issue:1

    Topics: Antioxidants; Biphenyl Compounds; Euphorbiaceae; Oleanolic Acid; Phenols; Picrates; Terpenes; Triterpenes

2013
Two new phthalate derivatives from Nepeta clarkei (Labiatae).
    Journal of Asian natural products research, 2012, Volume: 14, Issue:1

    Topics: Molecular Structure; Nepeta; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pakistan; Phthalic Acids; Stereoisomerism

2012
Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage.
    Acta biochimica Polonica, 2012, Volume: 59, Issue:2

    Topics: Antioxidants; Apoptosis; Cell Proliferation; DNA Replication; Humans; Inhibitory Concentration 50; Keratinocytes; Leuzea; Oleanolic Acid; Plant Extracts; Plant Leaves; Reactive Oxygen Species

2012
The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors.
    British journal of pharmacology, 2012, Volume: 167, Issue:8

    Topics: Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Brain; CHO Cells; Cricetinae; Cricetulus; Endocannabinoids; Glycerides; Humans; Hydrolysis; Monoacylglycerol Lipases; Oleanolic Acid; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Swine; U937 Cells

2012
β-Amyrin oxidation by oat CYP51H10 expressed heterologously in yeast cells: the first example of CYP51-dependent metabolism other than the 14-demethylation of sterol precursors.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:5

    Topics: Avena; Genes, Plant; Oleanolic Acid; Phytosterols; Saponins; Sterol 14-Demethylase; Yeasts

2012
[Triterpene compounds from Cirsium setosum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7

    Topics: Chromatography, High Pressure Liquid; Cirsium; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pentacyclic Triterpenes; Sterols; Triterpenes

2012
Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus.
    Planta, 2012, Volume: 236, Issue:5

    Topics: Arabidopsis; Biosynthetic Pathways; Catharanthus; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA, Complementary; Expressed Sequence Tags; Gene Expression Regulation, Plant; Intramolecular Transferases; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Plant Proteins; Plants, Medicinal; Saccharomyces cerevisiae; Triterpenes; Ursolic Acid

2012
Antihyperglycemic and hypolipidemic effects of α, β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice.
    Lipids in health and disease, 2012, Aug-06, Volume: 11

    Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Drug Discovery; Fenofibrate; Glyburide; Hypercholesterolemia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin-Secreting Cells; Magnoliopsida; Male; Mice; Oleanolic Acid; Phytotherapy; Triglycerides

2012
Antimicrobial activity of bioactive compounds and leaf extracts in Jatropha tanjorensis.
    Fitoterapia, 2012, Volume: 83, Issue:7

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Humans; Jatropha; Microbial Sensitivity Tests; Oleanolic Acid; Plant Extracts; Plant Leaves; Pyrrolidinones; Stigmasterol; Triterpenes

2012
Composition and physiological function of the wax layers coating Arabidopsis leaves: β-amyrin negatively affects the intracuticular water barrier.
    Plant physiology, 2012, Volume: 160, Issue:2

    Topics: Agrobacterium tumefaciens; Alkanes; Arabidopsis; Cloning, Molecular; Dehydration; DNA, Complementary; Genes, Plant; Intramolecular Transferases; Oleanolic Acid; Plant Leaves; Plant Stomata; Plant Transpiration; Structure-Activity Relationship; Transformation, Genetic; Triterpenes; Water; Waxes

2012
Triterpenoid content of berries and leaves of bilberry Vaccinium myrtillus from Finland and Poland.
    Journal of agricultural and food chemistry, 2012, Dec-05, Volume: 60, Issue:48

    Topics: Anthocyanins; Cholesterol; Finland; Fruit; Gas Chromatography-Mass Spectrometry; Molecular Structure; Oleanolic Acid; Phytosterols; Plant Extracts; Plant Leaves; Poland; Sitosterols; Triterpenes; Vaccinium myrtillus

2012
Evaluation of ethnomedical claim III: anti-hyperglycemic activities of Gongronema latifolium root and stem.
    Journal of diabetes, 2013, Volume: 5, Issue:3

    Topics: Animals; Apocynaceae; Blood Glucose; Cell Line, Tumor; Chromatography, Liquid; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Glucose; Glyburide; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulinoma; Male; Methanol; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Plant Stems; Rats; Rats, Wistar; Treatment Outcome

2013
Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Anti-Bacterial Agents; Betulinic Acid; Drug Resistance, Microbial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Oleanolic Acid; Pentacyclic Triterpenes; Staphylococcal Infections; Triterpenes

2013
Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system.
    Molecular immunology, 2013, Volume: 54, Issue:3-4

    Topics: Administration, Oral; Amidohydrolases; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Asialoglycoproteins; Body Weight; Cannabinoids; CD18 Antigens; Cell Adhesion Molecules; Chemokines; Colitis; Colon; Dextran Sulfate; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-4; Ki-67 Antigen; Lectins, C-Type; Male; Membrane Proteins; Mice; Oleanolic Acid; P-Selectin; Peroxidase; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1

2013
Triterpene esters: natural products from Dorstenia arifolia (Moraceae).
    Molecules (Basel, Switzerland), 2013, Apr-11, Volume: 18, Issue:4

    Topics: Acetic Acid; Esters; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Moraceae; Oleanolic Acid; Plant Extracts; Triterpenes

2013
[Study on the chemical constituents in Pouzolzia zeylanica].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:11

    Topics: Catechin; Chromatography, Thin Layer; Glycosides; Oleanolic Acid; Sitosterols; Urticaceae

2012
[Chemical constituents of Gentiana rhodantha].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:3

    Topics: Chromatography, Gel; Chromatography, Reverse-Phase; Dextrans; Gentianaceae; Mass Spectrometry; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Quercetin; Salicylic Acid; Silica Gel; Triterpenes; Ursolic Acid; Xanthones

2013
A non-michaelian behavior of the in vitro metabolism of the pentacyclic triterpene alfa and beta amyrins by employing rat liver microsomes.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 84

    Topics: Animals; Drug Discovery; Gas Chromatography-Mass Spectrometry; Isomerism; Kinetics; Male; Microsomes, Liver; Oleanolic Acid; Pentacyclic Triterpenes; Rats; Rats, Wistar

2013
Chemical constituents from the stem barks of Garcinia multiflora.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:11

    Topics: Benzophenones; Biphenyl Compounds; Coumaric Acids; Drugs, Chinese Herbal; Garcinia; Molecular Structure; Oleanolic Acid; Plant Bark; Triterpenes; Xanthones

2013
Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis.
    Journal of natural products, 2013, Sep-27, Volume: 76, Issue:9

    Topics: Crystallography, X-Ray; Inhibitory Concentration 50; Iran; Lactones; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Parasitic Sensitivity Tests; Plasmodium falciparum; Salvia; Stereoisomerism; Triterpenes; Trypanosoma brucei rhodesiense

2013
Potent microbial and tyrosinase inhibitors from stem bark of Bauhinia rufescens (Fabaceae).
    Natural product communications, 2013, Volume: 8, Issue:10

    Topics: Anti-Bacterial Agents; Bauhinia; Glycosides; Inositol; Microbial Sensitivity Tests; Monophenol Monooxygenase; Oleanolic Acid; Oxepins; Plant Bark; Plant Stems; Plants, Medicinal; Stilbenes

2013
Anticancer activity of the roots of Ichnocarpus frutescens R. Br. and isolated triterpenes.
    Pakistan journal of pharmaceutical sciences, 2014, Volume: 27, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apocynaceae; Cell Line, Tumor; Humans; Oleanolic Acid; Plant Extracts; Plant Roots; Triterpenes; Ursolic Acid

2014
[Chemical constituents of Lysimachia paridiformis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:7

    Topics: Luteolin; Magnetic Resonance Spectroscopy; Oleanolic Acid; Primulaceae; Quercetin; Stigmasterol

2013
[Study on the chemical constituents of mori cortex].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:7

    Topics: Chromatography, Thin Layer; Molecular Structure; Morus; Oleanolic Acid; Plant Bark; Plant Roots; Sitosterols; Vitamin E

2013
Potential targets by pentacyclic triterpenoids from Callicarpa farinosa against methicillin-resistant and sensitive Staphylococcus aureus.
    Fitoterapia, 2014, Volume: 94

    Topics: Anti-Infective Agents; Betulinic Acid; Callicarpa; Gene Expression Regulation, Bacterial; Magnetic Resonance Spectroscopy; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Staphylococcal Infections; Staphylococcus aureus; Transcriptome; Triterpenes

2014
Ethnopharmacology of Souroubea sympetala and Souroubea gilgii (Marcgraviaceae) and identification of betulinic acid as an anxiolytic principle.
    Phytochemistry, 2015, Volume: 113

    Topics: Animals; Anti-Anxiety Agents; Betulinic Acid; Costa Rica; Diazepam; Dose-Response Relationship, Drug; Ethnopharmacology; Fruit; Magnoliopsida; Male; Medicine, Traditional; Oleanolic Acid; Pentacyclic Triterpenes; Phytochemicals; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Triterpenes

2015
β-Amyrin synthase from Euphorbia tirucalli. Steric bulk, not the π-electrons of Phe, at position 474 has a key role in affording the correct folding of the substrate to complete the normal polycyclization cascade.
    Organic & biomolecular chemistry, 2014, Jun-21, Volume: 12, Issue:23

    Topics: Chromatography, Gas; Cyclization; Electrons; Euphorbia; Intramolecular Transferases; Mutagenesis, Site-Directed; Mutant Proteins; Oleanolic Acid; Phenylalanine; Structure-Activity Relationship; Substrate Specificity

2014
Triterpenoid saponin biosynthetic pathway profiling and candidate gene mining of the Ilex asprella root using RNA-Seq.
    International journal of molecular sciences, 2014, Apr-09, Volume: 15, Issue:4

    Topics: Base Sequence; Biosynthetic Pathways; Data Mining; Databases, Genetic; Drugs, Chinese Herbal; Erythritol; Gene Expression; Gene Expression Profiling; Genes, Plant; Ilex; Mevalonic Acid; Oleanolic Acid; Phylogeny; Plant Extracts; Plant Roots; Saponins; Sequence Analysis, DNA; Sequence Analysis, RNA; Squalene; Transcriptome; Triterpenes

2014
Klodorone A and klodorol A: new triterpenes from Kleinia odora.
    Natural product research, 2014, Volume: 28, Issue:15

    Topics: Asteraceae; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Saudi Arabia; Triterpenes

2014
Synergistic action of compounds isolated from the hexane extract of Ardisia crispa root against tumour-promoting effect, in vitro.
    Natural product research, 2014, Volume: 28, Issue:22

    Topics: Anticarcinogenic Agents; Antigens, Viral; Ardisia; Benzoquinones; Curcumin; Gas Chromatography-Mass Spectrometry; Hexanes; Humans; Oleanolic Acid; Plant Roots; Quinones; Triterpenes

2014
Langmuir monolayer studies of the interaction of monoamphiphilic pentacyclic triterpenes with anionic mitochondrial and bacterial membrane phospholipids - searching for the most active terpene.
    Biochimica et biophysica acta, 2014, Volume: 1838, Issue:10

    Topics: Bacteria; Cell Membrane; Membranes, Artificial; Mitochondrial Membranes; Oleanolic Acid; Pentacyclic Triterpenes; Phospholipids

2014
Investigation of triterpene synthesis and regulation in oats reveals a role for β-amyrin in determining root epidermal cell patterning.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jun-10, Volume: 111, Issue:23

    Topics: Avena; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Glucuronidase; Green Fluorescent Proteins; Intramolecular Transferases; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oleanolic Acid; Phylogeny; Plant Epidermis; Plant Proteins; Plant Roots; Plants, Genetically Modified; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Transcriptome; Triterpenes

2014
β-Amyrin biosynthesis: the critical role of steric volume at C-19 of 2,3-oxidosqualene for its correct folding to generate the pentacyclic scaffold.
    Organic letters, 2014, Jul-03, Volume: 16, Issue:13

    Topics: Cyclization; Intramolecular Transferases; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Squalene

2014
Amyrin attenuates scopolamine-induced cognitive impairment in mice.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:7

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; MAP Kinase Signaling System; Memory; Mice, Inbred ICR; Muscarinic Antagonists; Oleanolic Acid; Scopolamine

2014
beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity.
    Pharmaceutical biology, 2014, Volume: 52, Issue:11

    Topics: Alstonia; Animals; Anti-Inflammatory Agents; Edema; Female; Male; Mice; Oleanolic Acid; Plant Bark; Plant Extracts; Plant Stems; Rats

2014
Reduction of adhesion molecule production and alteration of eNOS and endothelin-1 mRNA expression in endothelium by Euphorbia hirta L. through its beneficial β-amyrin molecule.
    Molecules (Basel, Switzerland), 2014, Jul-18, Volume: 19, Issue:7

    Topics: Cell Line; Endothelial Cells; Endothelin-1; Euphorbia; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Nitric Oxide Synthase Type III; Oleanolic Acid; RNA, Messenger; Vascular Cell Adhesion Molecule-1

2014
Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils.
    Biological research, 2014, Apr-01, Volume: 47

    Topics: Alkanes; Anti-Infective Agents; Antioxidants; Aspergillus; Bacillus cereus; Candida albicans; Disk Diffusion Antimicrobial Tests; Escherichia coli; Gas Chromatography-Mass Spectrometry; Lamiaceae; Lipid Peroxidation; Methyl Ethers; Microbial Sensitivity Tests; Oils, Volatile; Oleanolic Acid; Palmitic Acid; Pentacyclic Triterpenes; Plant Leaves; Plant Oils; Plant Stems; Reducing Agents; Sesquiterpenes; Staphylococcus; Stearic Acids

2014
Extracellular lipids of Camelina sativa: characterization of chloroform-extractable waxes from aerial and subterranean surfaces.
    Phytochemistry, 2014, Volume: 106

    Topics: Brassicaceae; Caffeic Acids; Coumaric Acids; Flowers; Lipids; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Plant Roots; Plant Stems; Seeds; Waxes

2014
Preparation and in vitro evaluation of α and β-amyrins loaded nanoemulsions.
    Current pharmaceutical biotechnology, 2013, Volume: 14, Issue:15

    Topics: Drug Compounding; Drug Liberation; Emulsions; Nanoparticles; Oleanolic Acid; Particle Size; Solubility

2013
Enhanced pathway efficiency of Saccharomyces cerevisiae by introducing thermo-tolerant devices.
    Bioresource technology, 2014, Volume: 170

    Topics: Adaptation, Physiological; Analysis of Variance; Biosynthetic Pathways; Cell Survival; Congo Red; Genetic Engineering; Heat-Shock Proteins; Hot Temperature; Oleanolic Acid; Polymerase Chain Reaction; Saccharomyces cerevisiae; Trehalose

2014
Enhancing the accumulation of beta-amyrin in Saccharomyces cerevisiae by co-expression of Glycyrrhiza uralensis squalene synthase 1 and beta-amyrin synthase genes.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:5

    Topics: Farnesyl-Diphosphate Farnesyltransferase; Glycyrrhiza uralensis; Intramolecular Transferases; Oleanolic Acid; Plant Proteins; Recombinant Proteins; Saccharomyces cerevisiae

2014
Anti-inflammatory potential of β-amyrin, a triterpenoid isolated from Costus igneus.
    Inflammopharmacology, 2014, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Costus; Diclofenac; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Humans; India; Inflammation; Interleukin-6; Leukocytes, Mononuclear; Male; Medicine, Traditional; NF-kappa B; Oleanolic Acid; Plant Leaves; Rats; Rats, Sprague-Dawley

2014
Studies of the interactions of ursane-type bioactive terpenes with the model of Escherichia coli inner membrane-Langmuir monolayer approach.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:2

    Topics: Cardiolipins; Cell Membrane; Escherichia coli; Hydrophobic and Hydrophilic Interactions; Kinetics; Membranes, Artificial; Oleanolic Acid; Phosphatidylethanolamines; Phosphatidylglycerols; Static Electricity; Thermodynamics; Triterpenes; Ursolic Acid

2015
Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids.
    Phytochemistry, 2014, Volume: 108

    Topics: Cytochrome P-450 Enzyme System; Medicago truncatula; Oleanolic Acid; Saccharomyces cerevisiae; Saponins; Triterpenes

2014
Alterations in brain amino acid metabolism and inhibitory effects on PKC are possibly correlated with anticonvulsant effects of the isomeric mixture of α- and β-amyrin from Protium heptaphyllum.
    Pharmaceutical biology, 2015, Volume: 53, Issue:3

    Topics: Amino Acids; Animals; Anticonvulsants; Brain; Burseraceae; Male; Mice; Oleanolic Acid; Protein Kinase C; Protein Kinase Inhibitors; Seizures; Stereoisomerism; Treatment Outcome

2015
Modulatory potential of α-amyrin against hepatic oxidative stress through antioxidant status in Wistar albino rats.
    Journal of ethnopharmacology, 2015, Feb-23, Volume: 161

    Topics: Alstonia; Animals; Carbon Tetrachloride; Liver; Male; Oleanolic Acid; Oxidative Stress; Plant Bark; Rats, Wistar

2015
Grazing incidence diffraction studies of the interactions between ursane-type antimicrobial triterpenes and bacterial anionic phospholipids.
    Colloids and surfaces. B, Biointerfaces, 2015, Apr-01, Volume: 128

    Topics: Anti-Infective Agents; Cardiolipins; Crystallization; Escherichia coli; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Oleanolic Acid; Phosphatidylglycerols; Thermodynamics; Triterpenes; Ursolic Acid

2015
New pimarane diterpenes and other antimycobacterial metabolites from Anisochilus verticillatus.
    Natural product research, 2016, Volume: 30, Issue:6

    Topics: Abietanes; Antitubercular Agents; Crystallography, X-Ray; Eugenol; Lamiaceae; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oleanolic Acid; Triterpenes; Ursolic Acid

2016
Positive effects of β-amyrin on pentobarbital-induced sleep in mice via GABAergic neurotransmitter system.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Animals; Bicuculline; Brain; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice, Inbred ICR; Molecular Structure; Oleanolic Acid; Pentobarbital; Random Allocation; Sleep; Sleep Aids, Pharmaceutical; Time Factors; Wakefulness-Promoting Agents

2015
Are Isoursenol and γ-Amyrin Rare Triterpenes in Nature or Simply Overlooked by Usual Analytical Methods?
    Organic letters, 2015, Aug-21, Volume: 17, Issue:16

    Topics: Intramolecular Transferases; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes

2015
Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana.
    The Plant journal : for cell and molecular biology, 2015, Volume: 84, Issue:3

    Topics: Barbarea; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Genome, Plant; Herbivory; Intramolecular Transferases; Nicotiana; Oleanolic Acid; Pentacyclic Triterpenes; Phylogeny; Plant Proteins; Plants, Genetically Modified; Quantitative Trait Loci; Sapogenins; Saponins; Triterpenes

2015
β-Amyrin Biosynthesis: The Methyl-30 Group of (3S)-2,3-Oxidosqualene Is More Critical to Its Correct Folding To Generate the Pentacyclic Scaffold than the Methyl-24 Group.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Oct-26, Volume: 21, Issue:44

    Topics: Catalysis; Euphorbia; Intramolecular Transferases; Molecular Conformation; Molecular Structure; Oleanolic Acid; Squalene; Triterpenes

2015
[Study on Chemical Composition of Phyllanthus emblica].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:2

    Topics: Betulinic Acid; Gallic Acid; Oleanolic Acid; Pentacyclic Triterpenes; Phyllanthus emblica; Phytochemicals; Plants, Medicinal; Quercetin; Rutin; Triterpenes; Ursolic Acid

2015
Densitometric validation and analysis of biomarker β-amyrin in different Acacia species (leaves) grown in Kingdom of Saudi Arabia by high performance thin-layer chromatography.
    Pakistan journal of pharmaceutical sciences, 2015, Volume: 28, Issue:4 Suppl

    Topics: Acacia; Biomarkers; Chromatography, Thin Layer; Densitometry; Oleanolic Acid; Plant Leaves; Reproducibility of Results

2015
β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway.
    Biochemical and biophysical research communications, 2015, Nov-27, Volume: 467, Issue:4

    Topics: Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oleanolic Acid; Proto-Oncogene Proteins c-akt; Signal Transduction

2015
Bio-guided Isolation of a New Sesterterpene from Serjania goniocarpa.
    Natural product communications, 2015, Volume: 10, Issue:9

    Topics: Cell Line, Tumor; Humans; Medicine, Traditional; Molecular Structure; Oleanolic Acid; Plant Extracts; Plant Leaves; Sapindaceae; Sesquiterpenes; Sesterterpenes

2015
[Chemical Constituents of Ethyl Acetate Fraction of Suaeda glauca].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:4

    Topics: Acetates; Chenopodiaceae; Glucosides; Luteolin; Oleanolic Acid; Phytochemicals; Plant Extracts; Quercetin; Sitosterols; Stigmasterol

2015
[Chemical Constituents from Claoxylon indicum Stems].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:4

    Topics: Euphorbiaceae; Oleanolic Acid; Phytochemicals; Plant Stems; Sitosterols

2015
[Chemical Constituents from Leaves of Hibiscus syriacus and Their α-Glucosidase Inhibitory Activities].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:5

    Topics: alpha-Glucosidases; Apigenin; Glucosides; Glycoside Hydrolase Inhibitors; Hibiscus; Kaempferols; Luteolin; Oleanolic Acid; Phytochemicals; Plant Leaves; Sitosterols; Stigmasterol; Triterpenes

2015
Novel triterpene oxidizing activity of Arabidopsis thaliana CYP716A subfamily enzymes.
    FEBS letters, 2016, Volume: 590, Issue:4

    Topics: Arabidopsis; Arabidopsis Proteins; Cytochrome P-450 Enzyme System; Hydroxylation; Oleanolic Acid; Oxidation-Reduction; Phylogeny; Saccharomyces cerevisiae; Triterpenes

2016
[Triterpenoids from Leaves of Ilex latifolia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:8

    Topics: Coumaric Acids; Drugs, Chinese Herbal; Ilex; Magnetic Resonance Spectroscopy; Oleanolic Acid; Plant Leaves; Propionates; Sitosterols; Triterpenes

2015
[Chemical Constituents from Angelica keiskei].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:8

    Topics: Angelica; Flavonoids; Glucosides; Kaempferols; Oleanolic Acid; Phytochemicals; Quercetin

2015
β-Amyrin, a pentacyclic triterpene, exhibits anti-fibrotic, anti-inflammatory, and anti-apoptotic effects on dimethyl nitrosamine-induced hepatic fibrosis in male rats.
    Human & experimental toxicology, 2017, Volume: 36, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers; Dimethylnitrosamine; Inflammation; Liver; Liver Cirrhosis; Male; Microscopy, Electron, Transmission; Oleanolic Acid; Oxidative Stress; Rats; Rats, Wistar

2017
β-Amyrin Biosynthesis: Promiscuity for Steric Bulk at Position 23 in the Oxidosqualene Substrate and the Significance of Hydrophobic Interaction between the Methyl Group at Position 30 and the Binding Site.
    The Journal of organic chemistry, 2016, 08-05, Volume: 81, Issue:15

    Topics: Binding Sites; Cyclization; Hydrogen; Hydrophobic and Hydrophilic Interactions; Intramolecular Transferases; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Oleanolic Acid; Oxygen; Squalene; Stereoisomerism; Substrate Specificity; Triterpenes

2016
An Intronless β-amyrin Synthase Gene is More Efficient in Oleanolic Acid Accumulation than its Paralog in Gentiana straminea.
    Scientific reports, 2016, 09-14, Volume: 6

    Topics: Biocatalysis; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Gentiana; Intramolecular Transferases; Introns; Models, Molecular; Mutant Proteins; Oleanolic Acid; Phylogeny; Sequence Homology, Amino Acid; Transcription, Genetic

2016
Metabolic switching of astringent and beneficial triterpenoid saponins in soybean is achieved by a loss-of-function mutation in cytochrome P450 72A69.
    The Plant journal : for cell and molecular biology, 2017, Volume: 89, Issue:3

    Topics: Base Sequence; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Variation; Glycine max; Mixed Function Oxygenases; Molecular Structure; Mutation; Oleanolic Acid; Phylogeny; Plant Proteins; Saponins; Triterpenes

2017
Caffeoyl Triterpenoid Esters as Potential Anti-ischemic Stroke Agents from Celastrus orbiculatus.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Animals; Caffeic Acids; Celastrus; Cerebral Arterial Diseases; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Esters; Humans; Ischemia; Male; Molecular Conformation; Molecular Structure; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plant Bark; Plant Roots; Rats; Triterpenes

2016
Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene.
    Scientific reports, 2016, 11-22, Volume: 6

    Topics: Amino Acid Motifs; Binding Sites; Catalytic Domain; Intramolecular Transferases; Leucine; Maytenus; Molecular Docking Simulation; Mutagenesis, Site-Directed; Oleanolic Acid; Phylogeny; Plant Leaves; Plant Proteins; RNA, Plant; Sequence Alignment; Triterpenes

2016
α-Amyrin attenuates high fructose diet-induced metabolic syndrome in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:1

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Antioxidants; Diet, Carbohydrate Loading; Dose-Response Relationship, Drug; Fructose; Gene Expression Regulation; Hyperglycemia; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Liver; Male; Metabolic Syndrome; Oleanolic Acid; Oxidative Stress; PPAR alpha; Random Allocation; Rats, Wistar

2017
β-Amyrin synthase from Euphorbia tirucalli L. functional analyses of the highly conserved aromatic residues Phe413, Tyr259 and Trp257 disclose the importance of the appropriate steric bulk, and cation-π and CH-π interactions for the efficient catalytic ac
    Organic & biomolecular chemistry, 2016, 12-20, Volume: 15, Issue:1

    Topics: Catalytic Domain; Cations; Cyclization; Dammaranes; Euphorbia; Intramolecular Transferases; Oleanolic Acid; Polyenes; Squalene; Triterpenes

2016
Chemometric profile, antioxidant and tyrosinase inhibitory activity of Camel's foot creeper leaves (Bauhinia vahlii).
    Natural product research, 2018, Volume: 32, Issue:5

    Topics: Antioxidants; Bauhinia; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fatty Acids; Gas Chromatography-Mass Spectrometry; Monophenol Monooxygenase; Oleanolic Acid; Oleic Acids; Plant Extracts; Plant Leaves; Sitosterols

2018
Pathway engineering for the production of β-amyrin and cycloartenol in Escherichia coli-a method to biosynthesize plant-derived triterpene skeletons in E. coli.
    Applied microbiology and biotechnology, 2017, Volume: 101, Issue:17

    Topics: Arabidopsis; Escherichia coli; Farnesyl-Diphosphate Farnesyltransferase; Intramolecular Transferases; Metabolic Engineering; Metabolic Networks and Pathways; Oleanolic Acid; Phytosterols; Polyisoprenyl Phosphates; Sesquiterpenes; Squalene Monooxygenase; Triterpenes

2017
The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular reactivity in high-fat diet-induced obese mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:10

    Topics: Animals; Aorta, Thoracic; Body Weight; Diet, High-Fat; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mice; Obesity; Oleanolic Acid; Triterpenes; Vasoconstriction; Vasodilation

2017
Development, Physicochemical Characterization and In Vitro Anti-Inflammatory Activity of Solid Dispersions of α,β Amyrin Isolated from Protium Oilresin.
    Molecules (Basel, Switzerland), 2017, Sep-09, Volume: 22, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Burseraceae; Cell Line; Cell Survival; Humans; Hypromellose Derivatives; Inflammation; Lipopolysaccharides; Macrophages; Nitric Oxide; Oleanolic Acid; Plant Oils; Polyethylene Glycols; Povidone; Resins, Plant; Suspensions

2017
Two CYP716A subfamily cytochrome P450 monooxygenases of sweet basil play similar but nonredundant roles in ursane- and oleanane-type pentacyclic triterpene biosynthesis.
    The New phytologist, 2017, Volume: 214, Issue:2

    Topics: Acetates; Cyclopentanes; Cytochrome P-450 Enzyme System; Expressed Sequence Tags; Gene Expression Regulation, Plant; Ocimum basilicum; Oleanolic Acid; Oxylipins; Plant Proteins; Triterpenes

2017
Practical Synthesis of α-Amyrin, β-Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase.
    Archiv der Pharmazie, 2017, Volume: 350, Issue:12

    Topics: Drug Design; Enzyme Inhibitors; Humans; Intramolecular Transferases; Oleanolic Acid; Pentacyclic Triterpenes

2017
Evaluation of the Effect of Moringa peregrina Extract on Learning and Memory: Role of Oxidative Stress.
    Journal of molecular neuroscience : MN, 2017, Volume: 63, Issue:3-4

    Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Flavonoids; Hippocampus; Male; Maze Learning; Memory; Moringa; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Plant Extracts; Rats; Rats, Wistar; Rutin; Sitosterols

2017
Anti-Parkinsonian effects of β-amyrin are regulated via LGG-1 involved autophagy pathway in Caenorhabditis elegans.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2017, Dec-01, Volume: 36

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopaminergic Neurons; Microtubule-Associated Proteins; Neurodegenerative Diseases; Oleanolic Acid; Oxidative Stress; Parkinson Disease

2017
Cytochrome P450 CYP716A254 catalyzes the formation of oleanolic acid from β-amyrin during oleanane-type triterpenoid saponins biosynthesis in Anemone flaccida.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: Catalysis; Cytochrome P-450 Enzyme System; Oleanolic Acid; Ranunculaceae; Saponins

2018
Boosting 11-oxo-β-amyrin and glycyrrhetinic acid synthesis in Saccharomyces cerevisiae via pairing novel oxidation and reduction system from legume plants.
    Metabolic engineering, 2018, Volume: 45

    Topics: Cytochrome P-450 Enzyme System; Fabaceae; Glycyrrhetinic Acid; Oleanolic Acid; Oxidation-Reduction; Plant Proteins; Saccharomyces cerevisiae

2018
Cytotoxic activity of the bioactive principles from Ficus burtt-davyi.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2018, Apr-03, Volume: 53, Issue:4

    Topics: Caco-2 Cells; Catechin; Cell Survival; Ficus; Fruit; HEK293 Cells; Humans; MCF-7 Cells; Oleanolic Acid; Pentacyclic Triterpenes; Phytochemicals; Plant Extracts; Plants, Medicinal

2018
Allelopathic activity and chemical constituents of extracts from roots of
    Natural product research, 2019, Volume: 33, Issue:18

    Topics: Allelopathy; Euphorbia; Gas Chromatography-Mass Spectrometry; Germination; Hexanes; Lactuca; Magnetic Resonance Spectroscopy; Methanol; Molecular Structure; Oleanolic Acid; Pheromones; Plant Extracts; Plant Roots; Sorghum; Sterols; Triterpenes

2019
Metabolic Engineering of Glycyrrhizin Pathway by Over-Expression of Beta-amyrin 11-Oxidase in Transgenic Roots of Glycyrrhiza glabra.
    Molecular biotechnology, 2018, Volume: 60, Issue:6

    Topics: Agrobacterium; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Gene Transfer Techniques; Glycyrrhiza; Glycyrrhizic Acid; Metabolic Engineering; Oleanolic Acid; Plant Proteins; Plant Roots; Plants, Genetically Modified

2018
Chemical, molecular and structural studies of Boswellia species: β-Boswellic Aldehyde and 3-epi-11β-Dihydroxy BA as precursors in biosynthesis of boswellic acids.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Boswellia; Molecular Structure; Oleanolic Acid; Plant Stems; Prodrugs; Real-Time Polymerase Chain Reaction; Resins, Plant; Triterpenes

2018
An Improved Scalable Synthesis of α- and β-Amyrin.
    Molecules (Basel, Switzerland), 2018, 06-27, Volume: 23, Issue:7

    Topics: Oleanolic Acid; Triterpenes; Ursolic Acid

2018
Productive Amyrin Synthases for Efficient α-Amyrin Synthesis in Engineered Saccharomyces cerevisiae.
    ACS synthetic biology, 2018, 10-19, Volume: 7, Issue:10

    Topics: Amino Acid Sequence; Eriobotrya; Gas Chromatography-Mass Spectrometry; Intramolecular Transferases; Malus; Metabolic Engineering; Oleanolic Acid; Phylogeny; Plant Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Squalene

2018
Towards take-all control: a C-21β oxidase required for acylation of triterpene defence compounds in oat.
    The New phytologist, 2019, Volume: 221, Issue:3

    Topics: Acylation; Avena; Cytochrome P-450 Enzyme System; Genetic Association Studies; Hydroxylation; Mutation; Nicotiana; Oleanolic Acid; Oxidoreductases; Phylogeny; Tissue Scaffolds; Transcriptome; Triterpenes

2019
α, β-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARγ and C/EBPα in 3T3-L1 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line; Cell Survival; Down-Regulation; Fatty Acid-Binding Proteins; Glucose Transporter Type 4; Mice; Obesity; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; PPAR gamma

2019
Transcriptomic analysis in Anemone flaccida rhizomes reveals ancillary pathway for triterpene saponins biosynthesis and differential responsiveness to phytohormones.
    Chinese journal of natural medicines, 2019, Volume: 17, Issue:2

    Topics: Anemone; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Gene Expression Profiling; Gene Expression Regulation, Plant; Glycosyltransferases; Oleanolic Acid; Plant Growth Regulators; Plant Proteins; Plants, Medicinal; Rhizome; Saponins; Triterpenes

2019
Enhanced β-Amyrin Synthesis in Saccharomyces cerevisiae by Coupling An Optimal Acetyl-CoA Supply Pathway.
    Journal of agricultural and food chemistry, 2019, Apr-03, Volume: 67, Issue:13

    Topics: Acetyl Coenzyme A; Cytosol; Fermentation; Metabolic Engineering; Mevalonic Acid; Oleanolic Acid; Saccharomyces cerevisiae

2019
Bioactive triterpenoids from
    Natural product research, 2020, Volume: 34, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Components, Aerial; RAW 264.7 Cells; Sambucus; Triterpenes; Ursolic Acid

2020
[Study of heterologous efficient synthesis of β-amyrin and high-density fermentation].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:7

    Topics: Fermentation; Glycyrrhiza uralensis; Industrial Microbiology; Intramolecular Transferases; Metabolic Engineering; Oleanolic Acid; Saccharomyces cerevisiae

2019
Triterpenoid and Fatty Acid Contents from the Stem Bark of Cordia dichotoma (Forst f.).
    Folia medica, 2018, Dec-01, Volume: 60, Issue:4

    Topics: Cordia; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Medicine, Traditional; Oleanolic Acid; Plant Bark; Plant Extracts; Plants, Medicinal; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Triterpenes

2018
Inclusion Complexes of β and HPβ-Cyclodextrin with α, β Amyrin and In Vitro Anti-Inflammatory Activity.
    Biomolecules, 2019, 06-21, Volume: 9, Issue:6

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Lipopolysaccharides; Macrophages; Mice; Oleanolic Acid; Solubility

2019
Two new terpenoids from the leaves of
    Natural product research, 2021, Volume: 35, Issue:7

    Topics: Callicarpa; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Oleanolic Acid; Plant Extracts; Plant Leaves; Proton Magnetic Resonance Spectroscopy; Terpenes; Triterpenes; Ursolic Acid

2021
Molecular Docking and Molecular Dynamics Studies on Selective Synthesis of α-Amyrin and β-Amyrin by Oxidosqualene Cyclases from
    International journal of molecular sciences, 2019, Jul-15, Volume: 20, Issue:14

    Topics: Binding Sites; Ilex; Intramolecular Transferases; Molecular Docking Simulation; Oleanolic Acid; Pentacyclic Triterpenes; Plant Proteins; Protein Binding

2019
De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway.
    Scientific reports, 2019, 10-16, Volume: 9, Issue:1

    Topics: Chromosome Mapping; Erythritol; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Genome, Plant; Gymnema sylvestre; India; Microsatellite Repeats; Molecular Sequence Annotation; Oleanolic Acid; Plants, Medicinal; RNA, Long Noncoding; Squalene; Sugar Phosphates; Terpenes; Transcriptome; Vitamin E

2019
Triglyceride deficiency and diacylglycerol kinase1 activity lead to the upregulation of mevalonate pathway in yeast: A study for the development of potential yeast platform for improved production of triterpenoid.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020, Volume: 1865, Issue:6

    Topics: Acyltransferases; Diacylglycerol O-Acyltransferase; Ergosterol; Gene Expression Regulation, Fungal; Gene Knockout Techniques; Metabolic Networks and Pathways; Mevalonic Acid; Oleanolic Acid; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Squalene; Synthetic Biology; Transcriptional Activation; Triglycerides; Up-Regulation

2020
β-Amyrin supplementation ameliorates the toxic effect of glycerol in the kidney of rat model.
    Human & experimental toxicology, 2020, Volume: 39, Issue:7

    Topics: Acute Kidney Injury; Animals; Creatinine; Dietary Supplements; Disease Models, Animal; Female; Glycerol; Kidney; Oleanolic Acid; Protective Agents; Rats, Sprague-Dawley; Urea

2020
Structural elucidation and in vivo anti-arthritic activity of β-amyrin and polpunonic acid isolated from the root bark of Ziziphus abyssinica HochstEx. A Rich (Rhamnaceae).
    Bioorganic chemistry, 2020, Volume: 98

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; Female; Freund's Adjuvant; Male; Molecular Structure; Oleanolic Acid; Plant Bark; Plant Roots; Rats; Rats, Sprague-Dawley; Rhamnaceae; Structure-Activity Relationship; Triterpenes

2020
    Molecules (Basel, Switzerland), 2020, Apr-28, Volume: 25, Issue:9

    Topics: Benzophenones; Brazil; Chalcones; Chromatography, High Pressure Liquid; Clusiaceae; Dalbergia; Drug Design; Flavanones; Flavonoids; Isoflavones; Magnetic Resonance Spectroscopy; Oleanolic Acid; Phytochemicals; Plant Extracts; Pterocarpans; Terpenes; Triterpenes

2020
A systematic comparison of triterpenoid biosynthetic enzymes for the production of oleanolic acid in Saccharomyces cerevisiae.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Amino Acid Sequence; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Intramolecular Transferases; Oleanolic Acid; Plasmids; Saccharomyces cerevisiae; Sequence Alignment

2020
Molecular cloning and functional characterization of multiple ApOSCs from Andrographis paniculata.
    Chinese journal of natural medicines, 2020, Volume: 18, Issue:9

    Topics: Andrographis; Biosynthetic Pathways; Cloning, Molecular; Oleanolic Acid; Pentacyclic Triterpenes; Squalene; Triterpenes

2020
Cloning, Yeast Expression, and Characterization of a β-Amyrin C-28 Oxidase (CYP716A249) Involved in Triterpenoid Biosynthesis in Polygala tenuifolia.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:12

    Topics: Arabidopsis Proteins; Cloning, Molecular; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Oleanolic Acid; Phylogeny; Polygala; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Saponins; Triterpenes

2020
β-amyrin-induced apoptosis in Candida albicans triggered by calcium.
    Fungal biology, 2021, Volume: 125, Issue:8

    Topics: Antifungal Agents; Apoptosis; Calcium; Candida albicans; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; Reactive Oxygen Species

2021
α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced mouse model of NAFLD via the AMPK-mTORC1-SREBP1 signaling mechanism.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2021, Volume: 54, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Insulin Resistance; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oleanolic Acid; Sterol Regulatory Element Binding Protein 1

2021
The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from
    Molecules (Basel, Switzerland), 2021, Nov-11, Volume: 26, Issue:22

    Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Biosynthetic Pathways; Cyclization; Genes, Plant; Leucine; Maytenus; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Oleanolic Acid; Pentacyclic Triterpenes; Plant Proteins; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Triterpenes

2021
β-Amyrin ameliorates diabetic nephropathy in mice and regulates the miR-181b-5p/HMGB2 axis in high glucose-stimulated HK-2 cells.
    Environmental toxicology, 2022, Volume: 37, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose; HMGB2 Protein; In Situ Hybridization, Fluorescence; Mice; MicroRNAs; Oleanolic Acid

2022
Engineering
    Journal of agricultural and food chemistry, 2022, Jan-12, Volume: 70, Issue:1

    Topics: Industrial Microbiology; Intramolecular Transferases; Metabolic Engineering; Oleanolic Acid; Saccharomyces cerevisiae; Squalene

2022
Potential Efficacy of
    Molecules (Basel, Switzerland), 2022, Jul-18, Volume: 27, Issue:14

    Topics: Antitubercular Agents; Heat-Shock Proteins; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oleanolic Acid

2022
Aided-efflux and high production of β-amyrin realized by β-cyclodextrin in situ synthesized on surface of Saccharomyces cerevisiae.
    Biotechnology and bioengineering, 2023, Volume: 120, Issue:4

    Topics: beta-Cyclodextrins; Oleanolic Acid; Saccharomyces cerevisiae; Triterpenes

2023
Production of 11-Oxo-β-Amyrin in
    Journal of agricultural and food chemistry, 2023, Mar-01, Volume: 71, Issue:8

    Topics: Cytochrome P-450 Enzyme System; Oleanolic Acid; Oxidation-Reduction; Saccharomyces cerevisiae

2023
β-Amyrin ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress in mice.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:2

    Topics: Animals; Bleomycin; Lung; Mice; Oleanolic Acid; Oxidative Stress; Pulmonary Fibrosis

2023