Page last updated: 2024-08-21

oleanolic acid and asiatic acid

oleanolic acid has been researched along with asiatic acid in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's3 (12.00)29.6817
2010's17 (68.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Cosentino, LM; Fujioka, T; Hu, CQ; Ikeshiro, Y; Kashiwada, Y; Kitanaka, S; Kozuka, M; Lee, KH; Nagao, T; Okabe, H; Wang, HK; Yamagishi, T; Yasuda, I; Yeh, E1
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN1
Auwerx, J; Boudjelal, G; Genet, C; Lobstein, A; Saladin, R; Schmidt, C; Schoonjans, K; Souchet, M; Strehle, A; Wagner, A1
Acebey-Castellon, IL; Bouthagane, N; Doan Thi Mai, H; Gangloff, SC; Hung, NV; Lavaud, C; Le Magrex Debar, E; Litaudon, M; Muhammad, D; Roseau, N; Sevenet, T; Voutquenne-Nazabadioko, L1
Chen, J; Chen, L; Cheng, K; Gong, Y; Hao, J; Jiang, H; Li, H; Li, L; Liang, Z; Liu, H; Liu, J; Luo, C; Sun, H; Wen, X; Zhang, L; Zhang, P; Zhang, X; Zheng, M; Zhu, X1
El-Kabbani, O; Endo, S; Hara, A; Iinuma, M; Matsunaga, T; Soda, M; Tajima, K; Takemura, M; Zhao, HT1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Feng, Y; Mei, Z; Wang, C; Yang, G; Yang, J; Yang, X; Zhao, P; Zhou, Q1
Feng, B; Hou, XY; Shi, JJ; Zhang, CL; Zhao, CH; Zhao, LX1
Li, H; Tian, S; Wang, C; Wei, X; Wu, P; Xu, L; Xue, J1
Alho, DPS; Figueiredo, SAC; Gonçalves, BMF; Leal, AS; Mendes, VIS; Salvador, JAR; Silvestre, SM; Valdeira, AS1
Dong, YS; Sun, WL; Wen, C; Xing, Y; Xiu, ZL; Yu, XX; Zhang, BW1
Csuk, R; Fischer, L; Kahnt, M; Sommerwerk, S; Wiemann, J1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Buckle, R; Eldridge, GR; Ellis, M; Garo, E; Hu, JF; Huang, Z; Lawrence, JA; Norman, VL; Rathinavelu, S; Starks, CM; Williams, RB1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Ding, LL; Wang, SC; Wang, ZT1
Feng, B; Xu, J; Zhang, YQ; Zhao, CH; Zhao, LX1
Tsao, SM; Yin, MC1
Chen, Y; Feng, X; Liu, WJ; Ma, X; Zhao, YY1
Akagi, KI; Gunji, H; Hanaki, M; Hirose, K; Horii, S; Irie, K; Kawase, T; Midorikawa, S; Murakami, K; Taniwaki, S; Yoshioka, T1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1
Cui, H; Jin, C; Jin, M; Li, G; Wang, J; Wang, R; Ye, C; Zhou, W; Zhou, Y1
Karwowska, K; Petelska, AD; Urbaniak, W1

Reviews

2 review(s) available for oleanolic acid and asiatic acid

ArticleYear
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Indolequinones; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triterpenes

2017
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018

Other Studies

23 other study(ies) available for oleanolic acid and asiatic acid

ArticleYear
Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.
    Journal of natural products, 1998, Volume: 61, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Humans; Oleanolic Acid; Plants, Medicinal; Triterpenes; Viral Plaque Assay

1998
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes

2008
Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: 3T3-L1 Cells; Animals; Betulinic Acid; CHO Cells; Cricetinae; Cricetulus; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2010
Triterpenoid saponins from Symplocos lancifolia.
    Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Magnoliopsida; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Pseudomonas aeruginosa; Saponins; Staphylococcus aureus; Triterpenes; Vietnam

2011
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Enzyme Inhibitors; Glycogen Phosphorylase, Muscle Form; Models, Molecular; Molecular Conformation; Muscle, Skeletal; Pentacyclic Triterpenes; Quantitative Structure-Activity Relationship; Rabbits; Stereoisomerism

2011
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
    Journal of natural products, 2011, May-27, Volume: 74, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; HeLa Cells; HT29 Cells; Humans; Mitomycin; Models, Molecular; Molecular Structure; Mutation; Oleanolic Acid; Pentacyclic Triterpenes

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Animals; Cell Line; Chalcones; Crystallography, X-Ray; Eucalyptus; Glucose Transporter Type 4; Models, Molecular; Molecular Structure; Plant Leaves; Rats; Xanthenes

2014
Design, synthesis, and biofunctional evaluation of novel pentacyclic triterpenes bearing O-[4-(1-piperazinyl)-4-oxo-butyryl moiety as antiproliferative agents.
    Bioorganic & medicinal chemistry letters, 2015, Oct-15, Volume: 25, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pentacyclic Triterpenes; Piperazines; Structure-Activity Relationship

2015
Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Animals; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Interleukin-6; Macrophages; MCF-7 Cells; Mice; Molecular Structure; Myrtaceae; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Triterpenes; Tumor Necrosis Factor-alpha

2016
Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose.
    Bioorganic & medicinal chemistry letters, 2017, 11-15, Volume: 27, Issue:22

    Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Drug Synergism; Inhibitory Concentration 50; Kinetics; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes

2017
Transformation of asiatic acid into a mitocanic, bimodal-acting rhodamine B conjugate of nanomolar cytotoxicity.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship

2018
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
Optimized plant compound with potent anti-biofilm activity across gram-negative species.
    Bioorganic & medicinal chemistry, 2020, 03-01, Volume: 28, Issue:5

    Topics: Amines; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2020
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
[Studies on chemical constituents from root of Actinidia macrosperma].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:18

    Topics: Actinidia; Catechin; Glucosides; Hydroquinones; Oleanolic Acid; Pentacyclic Triterpenes; Plant Roots; Plants, Medicinal; Triterpenes

2007
Inhibition of human enterovirus 71 replication by pentacyclic triterpenes and their novel synthetic derivatives.
    Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:8

    Topics: Antiviral Agents; Enterovirus A, Human; Enterovirus Infections; Humans; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid; Virus Replication

2014
Antioxidative and antiinflammatory activities of asiatic acid, glycyrrhizic acid, and oleanolic acid in human bronchial epithelial cells.
    Journal of agricultural and food chemistry, 2015, Apr-01, Volume: 63, Issue:12

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Bronchi; Cell Line; Epithelial Cells; Glycyrrhizic Acid; Humans; Hydrogen Peroxide; Oleanolic Acid; Pentacyclic Triterpenes; Reactive Oxygen Species

2015
[Study on Chemical Constituents from Roots of Lonicera macranthoides].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:12

    Topics: Lonicera; Oleanolic Acid; Pentacyclic Triterpenes; Phytochemicals; Plant Roots; Sitosterols

2014
Role of the carboxy groups of triterpenoids in their inhibition of the nucleation of amyloid β42 required for forming toxic oligomers.
    Chemical communications (Cambridge, England), 2018, Jun-14, Volume: 54, Issue:49

    Topics: Amyloid beta-Peptides; Anthraquinones; Carboxylic Acids; Cell Line, Tumor; Humans; Lysine; Neuroprotective Agents; Oleanolic Acid; Pentacyclic Triterpenes; Peptide Fragments; Protein Multimerization; Triterpenes

2018
A new pentacyclic triterpenoid from the leaves of
    Natural product research, 2020, Volume: 34, Issue:23

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Drug Evaluation, Preclinical; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; RAW 264.7 Cells; Rhododendron; Triterpenes; Ursolic Acid

2020
The Equilibria of Triterpene Sapogenins-Phosphatidylcholine in Monolayers at the Air/Water Interface.
    International journal of molecular sciences, 2023, Nov-09, Volume: 24, Issue:22

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Lecithins; Oleanolic Acid; Sapogenins; Saponins; Surface Properties; Triterpenes; Water

2023