Page last updated: 2024-08-21

oleanolic acid and acetaminophen

oleanolic acid has been researched along with acetaminophen in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's4 (28.57)29.6817
2010's5 (35.71)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Jia, XS; Klaassen, CD; Liu, J; Liu, YP; Madhu, C; Mao, Q1
Klaassen, CD; Liu, J; Liu, Y1
Liu, GT; Shi, JZ1
Klaassen, CD; Liu, J; Liu, Y; Madhu, C1
Almeida, FR; Brito, GA; Chaves, MH; Lima, RC; Maia, JL; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM1
Abdel-Rahman, MM; Abdel-Zaher, AO; Hafez, MM; Omran, FM1
Aleksunes, LM; Klaassen, CD; Reisman, SA1
Buckley, DB; Klaassen, CD; Reisman, SA; Tanaka, Y1
Chen, Y; Grace-Lynn, C; Jothy, SL; Kanwar, JR; Latha, LY; Sasidharan, S; Vijayarathna, S1
Sharma, M1
Fang, Z; Gonzalez, FJ; Guo, B; Jiang, C; Kim, JH; Krausz, KW; Liu, A; Sun, L; Tanaka, N; Yang, J1
Cheng, G; Cheng, H; Ci, X; Lv, H; Wang, L; Zhang, S1
Deng, LL; He, X; Li, J; Li, YJ; Liao, SG; Liao, XM; Liu, T; Wang, M; Wang, YL; Xu, GB; Zhong, RF; Zhou, M1
Ding, D; Gai, C; Li, W; Li, Z; Lv, S; Wang, Y; Yu, M; Zhang, W; Zheng, J1

Other Studies

14 other study(ies) available for oleanolic acid and acetaminophen

ArticleYear
Protective effects of fulvotomentosides on acetaminophen-induced hepatotoxicity.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:3

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Inactivation, Metabolic; Male; Mice; Microsomes, Liver; Oleanolic Acid; Saponins

1992
Protective effect of oleanolic acid against chemical-induced acute necrotic liver injury in mice.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:2

    Topics: Acetaminophen; Animals; Cadmium Poisoning; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Male; Mice; Necrosis; Oleanolic Acid

1995
[Protective effect of the fulvotomentosides on paracetamol-induced hepatotoxicity in mice].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:4

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glutathione; Liver; Liver Diseases; Male; Mice; Oleanolic Acid; Saponins

1995
Protective effects of oleanolic acid on acetaminophen-induced hepatotoxicity in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3

    Topics: Acetaminophen; Animals; Biliary Tract; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glucuronosyltransferase; Glutathione; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oleanolic Acid; Subcellular Fractions; Uridine Diphosphate Glucuronic Acid

1993
Protective effect of alpha- and beta-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice.
    Journal of ethnopharmacology, 2005, Apr-08, Volume: 98, Issue:1-2

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Burseraceae; Disease Models, Animal; Drug Administration Schedule; Drug Synergism; Glutathione; Injections, Intraperitoneal; Liver Failure, Acute; Male; Mice; Necrosis; Oleanolic Acid; Pentobarbital; Phytotherapy; Plant Bark; Plants, Medicinal; Protective Agents; Resins, Plant; Sleep; Triterpenes

2005
Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage.
    Toxicology, 2007, May-05, Volume: 234, Issue:1-2

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gadolinium; Glutathione; Guanidines; Injections, Intramuscular; Kidney Diseases; Liver Diseases; Male; Nitric Oxide; Oleanolic Acid; Protective Agents; Rats; Rats, Wistar; Survival Analysis; Survival Rate

2007
Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes.
    Biochemical pharmacology, 2009, Apr-01, Volume: 77, Issue:7

    Topics: Acetaminophen; Animals; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2 Transcription Factor; Oleanolic Acid

2009
CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Imidazoles; Liver; Liver Diseases; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Necrosis; NF-E2-Related Factor 2; Nuclear Transfer Techniques; Oleanolic Acid; Response Elements; RNA, Messenger; Time Factors

2009
Evaluation of the hepatoprotective Effects of Lantadene A, a pentacyclic triterpenoid of Lantana plants against acetaminophen-induced liver damage.
    Molecules (Basel, Switzerland), 2012, Nov-23, Volume: 17, Issue:12

    Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Humans; Lantana; Liver; Mice; Oleanolic Acid; Plant Leaves; Protective Agents; Silymarin

2012
Remarks on Sasidharan et al. "Evaluation of the hepatoprotective effects of lantadene A, a pentacyclic triterpenoid of Lantana plants against acetaminophen-induced liver damage". Molecules 2012, 17, 13937-13947.
    Molecules (Basel, Switzerland), 2013, Mar-14, Volume: 18, Issue:3

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Humans; Oleanolic Acid

2013
Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling.
    Chemico-biological interactions, 2014, Nov-05, Volume: 223

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antipyretics; Bupleurum; Chemical and Drug Induced Liver Injury; Cytokines; Down-Regulation; Drugs, Chinese Herbal; Humans; Inactivation, Metabolic; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oleanolic Acid; Oxidative Stress; Plants, Medicinal; PPAR alpha; RNA, Messenger; Saponins; Signal Transduction; STAT3 Transcription Factor

2014
Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Acetaminophen; AMP-Activated Protein Kinases; Analgesics, Non-Narcotic; Animals; Apoptosis Inducing Factor; bcl-2-Associated X Protein; CRISPR-Cas Systems; Female; Gene Deletion; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Heme Oxygenase-1; Hep G2 Cells; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Superoxides

2016
Discovery and structure-activity relationship of auriculatone: A potent hepatoprotective agent against acetaminophen-induced liver injury.
    Bioorganic & medicinal chemistry letters, 2017, 08-15, Volume: 27, Issue:16

    Topics: Acetaminophen; Acetylcysteine; Binding Sites; Cell Line; Cell Survival; Cytochrome P-450 CYP3A; Glutathione; Humans; Liver; Molecular Docking Simulation; Oleanolic Acid; Protective Agents; Protein Structure, Tertiary; Structure-Activity Relationship

2017
Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer.
    Journal of cellular physiology, 2020, Volume: 235, Issue:4

    Topics: Acetaminophen; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Synergism; Ferroptosis; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lipid Peroxides; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Piperazines; Signal Transduction; Xenograft Model Antitumor Assays

2020