oleanolic acid has been researched along with Bardoxolone in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (4.76) | 18.2507 |
2000's | 4 (9.52) | 29.6817 |
2010's | 2 (4.76) | 24.3611 |
2020's | 34 (80.95) | 2.80 |
Authors | Studies |
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Gribble, GW; Honda, T; Rounds, BV; Sporn, MB; Suh, N; Wang, Y | 1 |
Bore, L; Favaloro, FG; Gribble, GW; Honda, T; Rounds, BV; Spor, MB; Suh, N; Wang, Y | 1 |
Bore, L; Favaloro, FG; Finlay, HJ; Gribble, GW; Honda, T; Rounds, BV; Sporn, MB; Suh, N; Wang, Y | 1 |
Favaloro, FG; Gribble, GW; Honda, T; Honda, Y; Place, AE; Rendi, MH; Sporn, MB; Suh, N | 1 |
Favaloro, FG; Gribble, GW; Honda, T; Honda, Y; Risingsong, R; Sporn, MB; Suh, N | 1 |
Anderson, AC; Browning, RG; Couch, RD; Gribble, GW; Honda, T; Sporn, MB; Wright, DL | 1 |
Callahan, JF; Kerns, JK; Moody, CJ; Wilson, AJ | 1 |
Csuk, R; Heller, L; Köwitsch, A; Perl, V; Schwarz, S; Siewert, B | 1 |
Huang, J; Ma, H; Wang, Y; Wang, Z; Yao, Z; Yu, J; Zhang, L; Zhang, W; Zhuang, C | 1 |
Aird, R; Andrews, TD; Brillant, N; Bunday, TM; Chan, BKY; Copple, IM; Elmasry, M; Fang, Y; Fenwick, SW; Forbes, SJ; Forootan, SS; Goldring, CE; Kitteringham, NR; Lister, A; Malik, HZ; Park, BK; Poptani, H; Ricci, E; Russomanno, G; Schofield, AL; Sharkey, JW; Sison-Young, RL; Starkey Lewis, PJ; Zhang, F | 1 |
Iwano, M; Kasuno, K; Yodoi, J | 1 |
Cao, W; Chen, XR; Dai, J; Deng, ZZ; Dong, J; Jiang, Q; Li, GC; Li, JW; Lin, JJ; Lv, ZY; Zhang, KJ | 1 |
Ilyina, AA; Markov, AV; Odarenko, KV; Zenkova, MA | 1 |
Bamford, RN; Bryant, BR; Conlon, KC; Daenthanasanmak, A; Green, PL; Homan, P; Karim, B; Miljkovic, MD; Petrus, MN; Thomas, CJ; Waldmann, TA; Yang, SM; Yoshioka, M | 1 |
Ahmed, H; Amin, U; Jia, Z; Li, Y; Pitts, DR; Sun, X; Zhu, H | 1 |
Akerman, A; Bahnson, E; Cartaya, A; Maiocchi, S; Thai, S | 1 |
Honda, T; Lee, J; Pandey, AK; Singh, K; Suzuki, CK; Thilagavathi, J; Venkatesh, S | 1 |
Baumel-Alterzon, S; Biswal, S; Brill, G; Garcia-Ocaña, A; Jean-Pierre, C; Katz, LS; Li, Y; Scott, DK; Tse, I | 1 |
Bhandari, R; Khatwani, N; Liby, KT; Park, C; Pioli, PA; Spezza, PA; Torres, GM; Yang, H | 1 |
Ali, KX; Casares, L; Cassin, L; Dayalan Naidu, S; de la Vega, L; Dinkova-Kostova, AT; Higgins, M; Honda, T; Kiib, AE; Minassi, A; Moreno, R; Neill, G; Olagnier, D; Poulsen, TB; Sayin, VI; Svenningsen, EB; Wiel, C | 1 |
Liu, X; Liu, Z; Ramirez, A | 1 |
Leehey, DJ | 1 |
Chan, CB; Chen, C; Chen, W; Cheng, M; Jiao, B; Nie, J; Wang, H; Xu, H; Yang, Q; Zhu, H; Zou, L | 1 |
Baker, J; Cooper, N; Fox, C; Higham, A; Lea, S; Li, J; Lucas, C; Montero-Fernandez, A; Murray, C; Shah, R; Singh, D | 1 |
Meng, Q; Wu, J; Wu, M; Xie, B; Xue, R; Yin, X | 1 |
Liu, L; Pan, X; Xiao, D; Xiao, J; Xie, F; Xu, X; Zhou, X | 1 |
Kim, JE; Kim, TH; Lee, DS; Park, H | 1 |
Fukiya, H; Horizono, J; Kai, H; Kamura, M; Kaseda, S; Koyama, Y; Kuwazuru, J; Nara, F; Niinou, S; Nishiyama, H; Ogi, S; Onuma, K; Sannomiya, Y; Sasaki, R; Shuto, T; Suico, MA; Sunamoto, H | 1 |
Cooper, SL; Hiemstra, S; Klip, JE; Middleton, A; Ter Braak, B; van de Water, B; White, A; Wink, S | 1 |
Bian, J; Cai, G; Gu, J; Liu, Z; Shi, J; Wang, Y; Xu, W; Yuan, Y; Zou, H | 1 |
Katori, Y; Nakayama, Y; Ogawa, T; Ohkoshi, A; Sporn, MB; Taguchi, K; Wakamori, S; Yamamoto, M | 1 |
Barluenga, S; Patouret, R; Winssinger, N | 1 |
Yamawaki, K | 1 |
Medrek, S; Melendres-Groves, L | 1 |
Ling, Y; Liu, GQ; Liu, Y; Meng, C; Qian, J; Ran, F; Wang, Y; Wu, H; Xu, Z; Yang, J; Zheng, H | 1 |
Chau, L; Kim, Y; Nguyen, BC; Rayalam, S; Taylor, E; Wang, X; Zhang, K | 1 |
Akuetteh, PDP; Hong, W; Huang, H; Jin, G; Lan, L; Shangguan, F; Wu, S; Yang, H; Zhang, Q; Zhou, H | 1 |
Anton, MI; Ciocoiu, M; Costea, CF; Floria, M; Gosav, EM; Hurjui, LL; Rezus, C; Seritean Isac, PN; Tanase, DM; Tarniceriu, CC | 1 |
Dai, L; Li, J; Lin, Z; Lu, L; Wu, J; Zhang, X | 1 |
Keino, H; Kudo, A; Nakayama, M; Saito, S; Sato, Y; Sugita, S | 1 |
Chen, T; Chen, Y; Li, Y; Shen, X; Tao, L; Xu, Y; Yang, H; Zhang, E | 1 |
Avula, UMR; Harris, L; Hassanein, M | 1 |
7 review(s) available for oleanolic acid and Bardoxolone
Article | Year |
---|---|
Urinary Thioredoxin as a Biomarker of Renal Redox Dysregulation and a Companion Diagnostic to Identify Responders to Redox-Modulating Therapeutics.
Topics: Acute Kidney Injury; Biomarkers; Female; Humans; Male; Oleanolic Acid; Oxidation-Reduction; Renal Insufficiency, Chronic; Thioredoxins | 2022 |
Targeting Inflammation in Diabetic Kidney Disease: Is There a Role for Pentoxifylline?
Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Multicenter Studies as Topic; Oleanolic Acid; Pentoxifylline; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening.
Topics: Animals; Antioxidants; Cytoskeletal Proteins; Kelch-Like ECH-Associated Protein 1; Keratins; Mice; Mucositis; NF-E2-Related Factor 2; Oleanolic Acid; Radiation Injuries; Stomatitis | 2022 |
[Challenges in kidney disease: therapeutic potential of bardoxolone methyl].
Topics: Humans; Kelch-Like ECH-Associated Protein 1; Kidney Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Quality of Life | 2022 |
Evolving nonvasodilator treatment options for pulmonary arterial hypertension.
Topics: Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Oleanolic Acid; Pulmonary Arterial Hypertension; Pulmonary Artery | 2022 |
Antiaging Mechanism of Natural Compounds: Effects on Autophagy and Oxidative Stress.
Topics: Autophagy; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species | 2022 |
Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives.
Topics: Antioxidants; Curcumin; Diabetic Nephropathies; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; Oxidative Stress; Quality of Life; Reactive Oxygen Species; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2022 |
35 other study(ies) available for oleanolic acid and Bardoxolone
Article | Year |
---|---|
Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Drug Design; Enzyme Inhibitors; Glucocorticoids; Interferon-gamma; Isoenzymes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleanolic Acid; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 1998 |
Novel synthetic oleanane triterpenoids: a series of highly active inhibitors of nitric oxide production in mouse macrophages.
Topics: Animals; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Saponins; Structure-Activity Relationship; Triterpenes | 1999 |
Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cells, Cultured; Female; Interferon-gamma; Macrophages, Peritoneal; Mice; Nitric Oxide; Oleanolic Acid; Peritonitis; Structure-Activity Relationship; Thioglycolates; Triterpenes | 2000 |
A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production.
Topics: Animals; Dexamethasone; Interferon-gamma; Macrophages; Mice; Molecular Structure; Nitric Oxide; Nitriles; Oleanolic Acid; Structure-Activity Relationship; Triterpenes | 2002 |
Design and synthesis of tricyclic compounds with enone functionalities in rings A and C: a novel class of highly active inhibitors of nitric oxide production in mouse macrophages.
Topics: Animals; In Vitro Techniques; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Nitriles; Peritonitis; Phenanthrenes; Stereoisomerism; Structure-Activity Relationship; Thioglycolates; Triterpenes | 2002 |
Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action.
Topics: Dithiothreitol; Kinetics; Molecular Conformation; Molecular Structure; Nitric Oxide; Oleanolic Acid; Spectrophotometry, Ultraviolet | 2005 |
Keap calm, and carry on covalently.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Drug Discovery; Esters; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Ketones; NF-E2-Related Factor 2; Protein Binding; Protein Conformation; Sulfoxides | 2013 |
Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2015 |
Discovery of bardoxolone derivatives as novel orally active necroptosis inhibitors.
Topics: Administration, Oral; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Necroptosis; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Systemic Inflammatory Response Syndrome | 2021 |
Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration.
Topics: Adult; Aged, 80 and over; Animals; Cells, Cultured; Female; Gene Expression Regulation; Hepatectomy; Hepatocytes; Humans; Liver; Liver Regeneration; Male; Mice; Mice, Knockout; Middle Aged; NF-E2-Related Factor 2; Oleanolic Acid; Primary Cell Culture | 2021 |
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Topics: Animals; Autophagy; Chondrocytes; Imidazoles; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Osteoarthritis; Tumor Necrosis Factor-alpha | 2022 |
Uncovering the anti-angiogenic effect of semisynthetic triterpenoid CDDO-Im on HUVECs by an integrated network pharmacology approach.
Topics: Human Umbilical Vein Endothelial Cells; Humans; Molecular Docking Simulation; Network Pharmacology; Oleanolic Acid; Triterpenes | 2022 |
Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukocytes, Mononuclear; Lymphoma; Mice; NF-kappa B; Oleanolic Acid; Phosphatidylinositol 3-Kinases | 2022 |
Triterpenoid CDDO-IM protects against lipopolysaccharide-induced inflammatory response and cytotoxicity in macrophages: The involvement of the NF-κB signaling pathway.
Topics: Cytokines; Humans; Inflammation; Lipopolysaccharides; Macrophages; NF-kappa B; Oleanolic Acid; Shock, Septic; Signal Transduction; Triterpenes | 2022 |
Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway.
Topics: Animals; Antioxidants; Mice; Mice, Inbred C57BL; Nanoparticles; NF-E2-Related Factor 2; Oleanolic Acid; Plaque, Atherosclerotic | 2022 |
Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives.
Topics: Adenosine Triphosphate; ATP-Dependent Proteases; Endopeptidases; Hydrolysis; Mitochondria; Mitochondrial Proteins; Oleanolic Acid | 2022 |
Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation.
Topics: Animals; Apoptosis; Cell Proliferation; Diabetes Mellitus; Glucose; Insulin; Insulin-Secreting Cells; Mice; NF-E2-Related Factor 2; Oleanolic Acid | 2022 |
T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.
Topics: Humans; Immunosuppressive Agents; Macrophages; Melanoma; Oleanolic Acid; T-Lymphocytes; Tumor Microenvironment | 2022 |
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity.
Topics: Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Triterpenes | 2022 |
Live Cell Imaging of Spatiotemporal Ca
Topics: Antineoplastic Agents; Apoptosis; Oleanolic Acid; Triterpenes | 2022 |
Rab13 Sustains Breast Cancer Stem Cells by Supporting Tumor-Stroma Cross-talk.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Neoplastic Stem Cells; Oleanolic Acid; rab GTP-Binding Proteins; Tumor Microenvironment | 2022 |
COPD lung studies of Nrf2 expression and the effects of Nrf2 activators.
Topics: Antioxidants; Humans; Lung; NF-E2-Related Factor 2; Oleanolic Acid; Pulmonary Disease, Chronic Obstructive; Superoxide Dismutase-1 | 2022 |
Nrf2-Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute-on-Chronic Liver Failure.
Topics: Acute-On-Chronic Liver Failure; Animals; Cyclooxygenase 2; Ferroptosis; Humans; Hydrogen Peroxide; Mice; NF-E2-Related Factor 2; Oleanolic Acid; RNA, Messenger | 2022 |
Design, synthesis and biological activity evaluation of a series of bardoxolone methyl prodrugs.
Topics: Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oleanolic Acid; Prodrugs; Signal Transduction | 2022 |
CDDO-Me Attenuates Clasmatodendrosis in CA1 Astrocyte by Inhibiting HSP25-AKT Mediated DRP1-S637 Phosphorylation in Chronic Epilepsy Rats.
Topics: Animals; Astrocytes; Dynamins; Epilepsy; Heat-Shock Proteins; Mitochondrial Dynamics; Oleanolic Acid; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats | 2022 |
Novel Keap1-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome Mouse Model.
Topics: Animals; Disease Models, Animal; Kelch-Like ECH-Associated Protein 1; Mice; Nephritis, Hereditary; NF-E2-Related Factor 2; Oleanolic Acid; Phenotype; Renal Insufficiency, Chronic | 2022 |
Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses.
Topics: Antioxidants; Hepatocytes; Humans; Liver; NF-E2-Related Factor 2; NF-kappa B; Oleanolic Acid; Oxidative Stress | 2022 |
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Topics: Animals; Depsipeptides; Hepatocytes; Liver Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Rats | 2022 |
Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication.
Topics: beta Karyopherins; Humans; Influenza, Human; Oleanolic Acid; Withania; Withanolides | 2022 |
Redox-Activatable Theranostic Co-Prodrug for Precise Tumor Diagnosis and Selective Combination Chemotherapy.
Topics: Animals; Cell Line, Tumor; Drug Therapy, Combination; Glutathione; Mice; Nanoparticles; Neoplasms; Oleanolic Acid; Oxidation-Reduction; Precision Medicine; Prodrugs; Reactive Oxygen Species; Theranostic Nanomedicine | 2022 |
Synthetic oleanane triterpenoid derivative CDDO-Me disrupts cellular bioenergetics to suppress pancreatic ductal adenocarcinoma via targeting SLC1A5.
Topics: Adenocarcinoma; Amino Acid Transport System ASC; Animals; Apoptosis; Cell Line, Tumor; Energy Metabolism; Humans; Mice; Mice, Nude; Minor Histocompatibility Antigens; Oleanolic Acid; Pancreatic Neoplasms; Reactive Oxygen Species; Triterpenes | 2022 |
Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa.
Topics: Adenosine Triphosphate; Bacterial Proteins; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Cruciform; Escherichia coli; Escherichia coli Proteins; Glucosides; Hydrolyzable Tannins; Molecular Docking Simulation; Oleanolic Acid; Pseudomonas aeruginosa; Recombination, Genetic | 2022 |
Genetic Ablation of Nrf2 Exacerbates Neuroinflammation in Ocular Autoimmunity.
Topics: Animals; Antioxidants; Autoimmune Diseases; Autoimmunity; Cytokines; Eye Proteins; Imidazolines; Interleukin-17; Interleukin-6; Mice; Mice, Knockout; Neuroinflammatory Diseases; NF-E2-Related Factor 2; Oleanolic Acid; Retinol-Binding Proteins; Uveitis | 2022 |
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Topics: Animals; Benzyl Alcohols; Cognitive Dysfunction; Cyclooxygenase 2; Dementia, Vascular; Ferroptosis; Glucosides; Glutathione; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; NF-E2-Related Factor 2; Oleanolic Acid; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Signal Transduction | 2022 |
Bardoxolone for CKD: The Paradox of Confusion and Dogma.
Topics: Humans; Oleanolic Acid; Renal Insufficiency, Chronic | 2022 |