olanzapine and titanium-dioxide

olanzapine has been researched along with titanium-dioxide* in 1 studies

Other Studies

1 other study(ies) available for olanzapine and titanium-dioxide

Article	Year
Development of a modified electrode with amine-functionalized TiO2/multi-walled carbon nanotubes nanocomposite for electrochemical sensing of the atypical neuroleptic drug olanzapine. Materials science & engineering. C, Materials for biological applications, 2013, Dec-01, Volume: 33, Issue:8 In this work, using of amine-functionalized TiO2/multi-walled carbon nanotubes (NH2-TiO2-MWCNTs) nanocomposite for modification of glassy carbon electrode (GCE) was investigated. The nanocomposite was characterized by Fourier transformed infrared spectroscopy, transmission electron microscopy and scanning electron microscopy. The efficiency of modified electrode for electrocatalytic the oxidation of olanzapine was studied by cyclic voltammetry, square wave voltammetry and chronoamperometry. The electrochemical measurements were carried out in phosphate-buffered solution (PBS, pH 5.0). The NH2-TiO2-MWCNTs/GCE provided high surface area and more sensitive performance. The charge transfer coefficient (α) and the apparent charge transfer rate constant (k(s)) were calculated to be equal to 0.42 and 0.173 s(-1), respectively. The square wave voltammetry exhibited two linear dynamic ranges and a detection limit of 0.09 μM of olanzapine. In addition, the modified electrode was employed for the determination of olanzapine in pharmaceutical and human blood serum samples in order to illustrate the applicability of proposed method. Topics: Amines; Antipsychotic Agents; Benzodiazepines; Catalysis; Electrochemical Techniques; Electrodes; Humans; Hydrogen-Ion Concentration; Nanocomposites; Nanotubes, Carbon; Olanzapine; Oxidation-Reduction; Surface Properties; Tablets; Titanium	2013

Article

Year

Development of a modified electrode with amine-functionalized TiO2/multi-walled carbon nanotubes nanocomposite for electrochemical sensing of the atypical neuroleptic drug olanzapine.

Materials science & engineering. C, Materials for biological applications, 2013, Dec-01, Volume: 33, Issue:8

In this work, using of amine-functionalized TiO2/multi-walled carbon nanotubes (NH2-TiO2-MWCNTs) nanocomposite for modification of glassy carbon electrode (GCE) was investigated. The nanocomposite was characterized by Fourier transformed infrared spectroscopy, transmission electron microscopy and scanning electron microscopy. The efficiency of modified electrode for electrocatalytic the oxidation of olanzapine was studied by cyclic voltammetry, square wave voltammetry and chronoamperometry. The electrochemical measurements were carried out in phosphate-buffered solution (PBS, pH 5.0). The NH2-TiO2-MWCNTs/GCE provided high surface area and more sensitive performance. The charge transfer coefficient (α) and the apparent charge transfer rate constant (k(s)) were calculated to be equal to 0.42 and 0.173 s(-1), respectively. The square wave voltammetry exhibited two linear dynamic ranges and a detection limit of 0.09 μM of olanzapine. In addition, the modified electrode was employed for the determination of olanzapine in pharmaceutical and human blood serum samples in order to illustrate the applicability of proposed method.

Topics: Amines; Antipsychotic Agents; Benzodiazepines; Catalysis; Electrochemical Techniques; Electrodes; Humans; Hydrogen-Ion Concentration; Nanocomposites; Nanotubes, Carbon; Olanzapine; Oxidation-Reduction; Surface Properties; Tablets; Titanium

2013