ofloxacin and tosufloxacin

ofloxacin has been researched along with tosufloxacin in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's11 (39.29)18.2507
2000's13 (46.43)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ1
Arika, T; Fukui, H; Iwatani, W; Maejima, T; Naito, T; Nakano, J; Senda, H; Shibata, T; Suda, M; Tatsumi, Y1
Chin, NX; Neu, HC1
Minami, S; Nishida, N; Noumi, T; Watanabe, Y; Yasuda, T1
Matsumoto, F; Morita, M; Takahashi, T1
Nagai, A; Nagasawa, M; Nakamura, S; Nishio, Y; Nojima, Y; Yoneda, T1
Fernandes, PB; Swanson, RN1
Chin, NX; Espinoza, AM; Neu, HC; Novelli, A1
Iwamoto, Y; Miyake, Y; Okuda, K; Suginaka, H; Tsuruda, K1
Mitsuhashi, S; Yoshida, T1
Fukuoka, Y; Ikeda, Y; Narita, H; Takahata, M; Todo, Y; Yamashiro, Y1
Hirayama, F; Ikeda, Y; Kawakita, T; Kuroda, T; Moriguchi, A; Sakurai, N; Sano, M; Uemori, S; Yamamoto, K1
Akiyama, H; Arata, J; Kanzaki, H; Tada, J; Yamasaki, O1
Aoyagi, K; Fujishima, M; Iida, M; Kimura, Y; Koga, H; Yoshimura, R1
Funato, T; Hongo, T; Igari, J; Iinuma, Y; Ishigo, S; Ishii, K; Ishii, M; Itoh, C; Iwata, M; Kaimori, M; Kaku, M; Kamihira, S; Kanda, M; Kashitani, F; Katoh, J; Kawahara, S; Kawamura, C; Kudoh, M; Kuwabara, M; Matsudou, Y; Matsushima, T; Miyashita, N; Miyazaki, S; Miyazaki, Y; Murakami, N; Nakagawa, K; Nakasone, I; Negayama, K; Niki, Y; Nisawataira, T; Oguri, T; Okada, J; Ono, J; Saito, Y; Sato, N; Taira, M; Takada, T; Takii, M; Tamaki, I; Tashiro, H; Tazawa, Y; Toyoshima, S; Tsujio, Y; Uehara, N; Ueno, K; Watanabe, N; Yamaguchi, K; Yamanaka, K; Yasujima, M; Yoshida, T1
Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H1
Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T1
Feng, P; Lei, BJ; Lv, XJ; Xia, PY; Zhong, L1
Araake, M; Hara, T; Nishino, T; Watabe, H1
Fujimoto, Y; Komeda, H; Takada, T; Uno, M; Yamada, Y1
Fukuda, Y; Mitsuyama, J; Takahata, M1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Omika, K; Sato, Y1
Ito, K; Izumi, K; Mikamo, H; Tamaya, T; Tanaka, K; Watanabe, K1
Hatou, S; Yamada, M; Yoshida, J1
Hatou, S; Minagawa, Y; Yamada, M; Yoshida, J; Yoshida, T1
Ishitoya, S; Kamoto, T; Ogawa, O; Okumura, K; Segawa, T; Yamamoto, S1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M1
Ayaki, M; Iwasawa, A; Niwano, Y1

Trials

2 trial(s) available for ofloxacin and tosufloxacin

ArticleYear
[Effectiveness of switch therapy for peritonitis].
    The Japanese journal of antibiotics, 2007, Volume: 60, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Ciprofloxacin; Clindamycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Health Care Costs; Humans; Injections, Intravenous; Meropenem; Middle Aged; Naphthyridines; Ofloxacin; Oxazines; Peritonitis; Thienamycins

2007
Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Cystitis; Fluoroquinolones; Humans; Levofloxacin; Male; Naphthyridines; Ofloxacin; Prospective Studies; Prostate; Prostatitis; Rectum

2008

Other Studies

26 other study(ies) available for ofloxacin and tosufloxacin

ArticleYear
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship

1992
Synthesis and antibacterial activity of novel 7-(3-substituted-3 or 4-trifluoromethyl-1-pyrrolidinyl)-8-methoxyfluoroquinolones.
    Bioorganic & medicinal chemistry letters, 1998, Oct-20, Volume: 8, Issue:20

    Topics: Anti-Infective Agents; Drug Resistance, Multiple; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; Pyrrolidines; Staphylococcus aureus

1998
In-vitro activity of WIN 57273 compared to the activity of other fluoroquinolones and two beta-lactam antibiotics.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 27, Issue:6

    Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones

1991
Intracellular activity of tosufloxacin (T-3262) against Salmonella enteritidis and ability to penetrate into tissue culture cells of human origin.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6

    Topics: Anti-Infective Agents; Cell Line; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Salmonella enteritidis

1990
[Therapeutic drug monitoring of fluoroquinolone].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48 Suppl

    Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum

1990
[Toxicity studies on T-3262 in rat upon intravenous injection for 14 days].
    The Japanese journal of antibiotics, 1989, Volume: 42, Issue:4

    Topics: Animals; Anti-Infective Agents; Body Weight; Bone Marrow; Drinking; Eating; Fluoroquinolones; Hematologic Tests; Injections, Intravenous; Kidney; Male; Mitomycin; Mitomycins; Naphthyridines; Ofloxacin; Organ Size; Rats; Rats, Inbred Strains

1989
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:6

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones

1988
Comparative in vitro activity of a new fluorinated 4-quinolone, T-3262 (A-60969).
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5

    Topics: Anti-Bacterial Agents; Bacteria; Ceftazidime; Ciprofloxacin; Fluoroquinolones; Gentamicins; Humans; Imipenem; Naphthyridines; Ofloxacin; Oxazines; Thienamycins

1988
In vitro activity of tetracyclines, macrolides, quinolones, clindamycin and metronidazole against periodontopathic bacteria.
    Journal of periodontal research, 1995, Volume: 30, Issue:4

    Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Clindamycin; Erythromycin; Fluoroquinolones; Metronidazole; Microbial Sensitivity Tests; Minocycline; Miocamycin; Naphthyridines; Ofloxacin; Porphyromonas gingivalis; Prevotella intermedia; Quinolones; Tetracycline

1995
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:4

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Dioxolanes; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Topoisomerase II Inhibitors

1993
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Lung Diseases; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Urinary Tract Infections

1993
Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents.
    Bioorganic & medicinal chemistry letters, 1998, Aug-18, Volume: 8, Issue:16

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Drug Stability; Fluoroquinolones; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Indicators and Reagents; Microbial Sensitivity Tests; Molecular Structure; Naphthyridines; Ofloxacin; Quinolones; Solutions; Structure-Activity Relationship; Ultraviolet Rays

1998
Streptococci isolated from various skin lesions: the interaction with Staphylococcus aureus strains.
    Journal of dermatological science, 1999, Volume: 19, Issue:1

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Erythromycin; Fluoroquinolones; Fusidic Acid; Humans; Imipenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillins; Skin Diseases, Bacterial; Species Specificity; Streptococcal Infections; Streptococcus; Vancomycin

1999
Can quinolones cause hemorrhagic colitis of late onset? Report of three cases.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:11

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Colitis; Colonoscopy; Enoxacin; Female; Fluoroquinolones; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Naphthyridines; Ofloxacin

1999
[Activities of antimicrobial agents against 5,180 clinical isolates obtained from 26 medical institutions during 1998 in Japan. Levofloxacin--Surveillance Group].
    The Japanese journal of antibiotics, 2000, Volume: 53, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Respiratory Tract Infections; Urinary Tract Infections

2000
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
    Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:2

    Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin

2000
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture].
    The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins

2000
Accumulation of ofloxacin and tosufloxacin in fluoroquinolone-resistant E coli.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:3

    Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Naphthyridines; Ofloxacin

2001
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones

2002
[Clinical study of male urethritis in Oogaki Municipal Hospital].
    Hinyokika kiyo. Acta urologica Japonica, 2005, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Chlamydia Infections; Fluoroquinolones; Gonorrhea; Hospitals, Municipal; Humans; Japan; Levofloxacin; Male; Middle Aged; Minocycline; Naphthyridines; Ofloxacin; Sexual Partners; Sexually Transmitted Diseases, Bacterial; Spectinomycin; Urethritis

2005
Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2006, Volume: 12, Issue:1

    Topics: Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Mutation; Naphthyridines; Ofloxacin; Pneumococcal Infections; Serum Bactericidal Test; Streptococcus pneumoniae; Treatment Outcome

2006
[Antibacterial activity of tosufloxacin against major organisms detected from patients with respiratory infections].
    The Japanese journal of antibiotics, 2007, Volume: 60, Issue:2

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Klebsiella pneumoniae; Levofloxacin; Moraxella catarrhalis; Naphthyridines; Ofloxacin; Pseudomonas aeruginosa; Respiratory Tract Infections; Streptococcus

2007
In vitro susceptibilities of bacterial isolates from conjunctival flora to gatifloxacin, levofloxacin, tosufloxacin, and moxifloxacin.
    Eye & contact lens, 2008, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aza Compounds; Bacteria; Child; Conjunctiva; Drug Resistance, Microbial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines

2008
Mutations in the quinolone resistance determining region in Staphylococcus epidermidis recovered from conjunctiva and their association with susceptibility to various fluoroquinolones.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:6

    Topics: Aza Compounds; Conjunctiva; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, MDR; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Staphylococcus epidermidis

2008
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures

2009
In vitro assessment of the cytotoxicity of six topical antibiotics to four cultured ocular surface cell lines.
    Biocontrol science, 2012, Volume: 17, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cefmenoxime; Cell Line; Cell Survival; Conjunctiva; Cornea; Dibekacin; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines; Rabbits

2012