ofloxacin and tobramycin

ofloxacin has been researched along with tobramycin in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.90)18.7374
1990's18 (26.09)18.2507
2000's33 (47.83)29.6817
2010's16 (23.19)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N1
Amblard, M; Bastide, L; Gualtieri, M; Leonetti, JP; Martinez, J; Pugniere, M; Roquet, F; Villain-Guillot, P1
Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL1
Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A1
Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z1
Lombardo, F; Obach, RS; Waters, NJ1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L1
Cattoir, V; Nordmann, P; Poirel, L1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bera, S; Mondal, D1
Gwon, A1
Gritz, DC; Gwon, A; Hubbard, BB; Lee, TY; McDonnell, PJ; Tang-Liu, D1
Maiche, AG; Teerenhovi, L1
Richman, J; Tang-Liu, D; Zolezio, H1
Beckman, G; Lima, PH; Nelson, JD; Silverman, V1
Chan, MK; Cheng, IK; Ng, WS1
Daschner, F; Kropec, A1
Grohe, K; Metzger, KG; Schacht, P; Zeiler, HJ1
Alfonso, E; Fink, NE; Maguire, MG; McDonnell, P; O'Brien, TP1
Discepola, MJ; Goldstein, DA; Jackson, WB; Kirsch, LS1
Gordon, YJ; Schwob, DL; Tang-Liu, DD; Usansky, JI1
Baker, RS; Casey, R; Flowers, CW; Fong, DS; Wilson, MR1
Flynn, CM; Johnson, DM; Jones, RN1
Durmaz, B; Durmaz, R; Günal, S; Hepsen, IF; Marol, S; Oram, O1
Majtán, V; Majtánová, L1
Beck, R; Drewelow, B; Guthoff, R; Hehl, EM; Kundt, G; Luthardt, K1
Igari, J; Nakamura, A; Oguri, T; Tabe, Y1
Beck, R; Drewelow, B; Guthoff, R; Hehl, EM; Luthard, K1
Ahuja, R; Panda, A; Sastry, SS1
Alexandrakis, G; Alfonso, EC; Miller, D1
Hostacká, A1
Lewis, K; Spoering, AL1
Ishii, Y; Kobayashi, T; Matsumoto, T; Miyazaki, S; Tateda, K; Yamaguchi, K1
Caballero, AR; Dajcs, JJ; Girgis, DO; Ke, TL; Moreau, JM; O'Callaghan, RJ; Schlech, BA; Stroman, DW; Thibodeaux, BA1
Baeyens, V; Buri, P; Felt, O; Gurny, R1
Fleiszig, SM; Lee, EJ; Mendoza, MN; Truong, TN1
Wu, XD; Yang, YH; Yao, K; Zhang, Z1
Field, TR; Moriarty, TF; Ramage, G; Storey, DG; Tunney, MM1
Burgess, DS; Hall, RG1
Fleisher, KE; Glickman, R; Hirsch, DL; Pahlavi, IA1
Alió, JL; Ferrer, C; Montero, J; Rodríguez, A; Ruiz-Moreno, JM1
Aktas, E; Durmaz, R; Kalcioglu, MT; Ozturan, O1
Adam, HJ; Laing, N; Mayer, M; Zhanel, GG1
Constantinou, M; Daniell, M; Snibson, GR; Taylor, HR; Vu, HT1
Eisen, L; Kim, J; Rosenberg, J1
Naranjo-Tackman, R; Stangogiannis-Druya, C; Stangogiannis-Druya, E; Vanzzini, V; Villar-Kurí, J1
Kim, EC; Kim, MS2
Dudley, MN; Griffith, DC; Miller, CE; Nolan, TG; Sabet, M; Senekeo-Effenberger, K1
Li, R; Liu, C; Sun, XG; Wang, ZQ1
Otuk, G; Ozbek, B1
Dai, YH; Huang, YS; Lan, J; Sun, SY; Xie, LX1
Balidis, MO; Mangioris, GF; Papadopoulos, NT; Papadopoulou, DN; Poulas, JL; Seiler, T1
Gordon, YJ; Kowalski, RP; Mah, FS; Romanowski, EG; Shanks, RM1
Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ1
Dudley, MN; Griffith, DC; Lomovskaya, O; Sabet, M; Tarazi, Z; Tsivkovskii, R1
Drewelow, B; Guthoff, RF; Mundkowski, RG; Schittkowski, MP; Wacke, R1
Drewelow, B; Guthoff, RF; Schittkowski, MP; Wacke, R1
Alba, LR; Jia, H; Kubin, CJ; Yoko Furuya, E1
Bai, N; Cai, Y; Kan, Q; Liang, B; Nie, X; Wang, R; Yang, J1
Chen, ZJ; Han, L; Sun, ST; Wang, LY; Yue, J; Zhang, YQ1
Grasso, DL; Lora, L; Muzzi, E; Orzan, E; Parentin, F; Pelos, G; Pensiero, S; Trabalzini, F1
Romero-Trevejo, JL; Somavilla-Lupiáñez, J1
Abdelkhalek, A; Bergstrom, BE; Hammac, GK; Seleem, MN; Townsend, WM; Younis, W1

Reviews

1 review(s) available for ofloxacin and tobramycin

ArticleYear
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019

Trials

12 trial(s) available for ofloxacin and tobramycin

ArticleYear
Ofloxacin vs tobramycin for the treatment of external ocular infection. Ofloxacin Study Group II.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:9

    Topics: Blepharitis; Colony Count, Microbial; Conjunctiva; Conjunctivitis, Bacterial; Corneal Ulcer; Double-Blind Method; Eyelids; Humans; Microbiological Techniques; Ofloxacin; Ophthalmic Solutions; Tobramycin; Treatment Outcome

1992
Empiric treatment of serious infections in patients with cancer: randomised comparison of two combinations.
    Infection, 1991, Volume: 19 Suppl 6

    Topics: Administration, Oral; Cefotaxime; Drug Synergism; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Neoplasms; Neutropenia; Ofloxacin; Tobramycin

1991
A randomized prospective trial of three different regimens of treatment of peritonitis in patients on continuous ambulatory peritoneal dialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1990, Volume: 15, Issue:2

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Bacteria; Cephalothin; Drug Therapy, Combination; Female; Humans; Injections, Intraperitoneal; Male; Middle Aged; Ofloxacin; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Prospective Studies; Randomized Controlled Trials as Topic; Rifampin; Tobramycin

1990
Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Report from the Bacterial Keratitis Study Research Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Cefazolin; Cephalosporins; Cornea; Corneal Ulcer; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Humans; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Prospective Studies; Tobramycin; Treatment Outcome

1995
Perioperative ofloxacin vs. tobramycin: efficacy in external ocular adnexal sterilization and anterior chamber penetration.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Aqueous Humor; Bacteria; Conjunctiva; Double-Blind Method; Drug Therapy, Combination; Erythromycin; Eyelids; Female; Humans; Male; Middle Aged; Ofloxacin; Ointments; Ophthalmic Solutions; Sterilization; Tobramycin

1995
Comparative tear concentrations over time of ofloxacin and tobramycin in human eyes.
    Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Double-Blind Method; Female; Half-Life; Humans; Male; Middle Aged; Ofloxacin; Reference Values; Tears; Time Factors; Tobramycin

1994
Aqueous humor penetration of topically applied ciprofloxacin, ofloxacin and tobramycin.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Aqueous Humor; Biological Assay; Ciprofloxacin; Female; Humans; Male; Middle Aged; Ofloxacin; Tobramycin

1997
Improved penetration of aminoglycosides and fluorozuinolones into the aqueous humour of patients by means of Acuvue contact lenses.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Aqueous Humor; Ciprofloxacin; Contact Lenses, Hydrophilic; Drug Delivery Systems; Eye Infections; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Staphylococcus epidermidis; Tobramycin

1999
Comparison of topical 0.3% ofloxacin with fortified tobramycin plus cefazolin in the treatment of bacterial keratitis.
    Eye (London, England), 1999, Volume: 13 ( Pt 6)

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefazolin; Cephalosporins; Corneal Ulcer; Double-Blind Method; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Humans; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Prospective Studies; Staphylococcal Infections; Tobramycin; Visual Acuity

1999
[Aqueous humor penetration of topically applied ofloxacin, ciprofloxacin and tobramycin].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2003, Volume: 39, Issue:12

    Topics: Administration, Topical; Aged; Aqueous Humor; Ciprofloxacin; Endophthalmitis; Female; Humans; Male; Middle Aged; Ofloxacin; Tobramycin

2003
Clinical efficacy of moxifloxacin in the treatment of bacterial keratitis: a randomized clinical trial.
    Ophthalmology, 2007, Volume: 114, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aza Compounds; Bacteria; Cefazolin; Child; Cornea; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Fluoroquinolones; Humans; Male; Middle Aged; Moxifloxacin; Ofloxacin; Prospective Studies; Quinolines; Tobramycin; Treatment Outcome

2007
[Study of different methods in reducing conjunctival bacteria before cataract surgery].
    Zhonghua yi xue za zhi, 2009, Sep-22, Volume: 89, Issue:35

    Topics: Aged; Antibiotic Prophylaxis; Cataract; Cataract Extraction; Conjunctiva; Humans; Levofloxacin; Middle Aged; Ofloxacin; Tobramycin

2009

Other Studies

56 other study(ies) available for ofloxacin and tobramycin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal

2007
Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Animals; Anti-Bacterial Agents; Biofilms; CHO Cells; Cricetinae; Cricetulus; DNA-Directed RNA Polymerases; Furans; Gram-Positive Bacteria; Microbial Sensitivity Tests; Rhodanine; Staphylococcus epidermidis; Structure-Activity Relationship

2007
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain

2007
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid

2007
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey

2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids

2008
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Topical ofloxacin in the treatment of Pseudomonas keratitis in a rabbit model.
    Cornea, 1992, Volume: 11, Issue:2

    Topics: Administration, Topical; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Disease Models, Animal; Eye Infections, Bacterial; Keratitis; Ofloxacin; Pseudomonas Infections; Rabbits; Tobramycin

1992
Comparison of ofloxacin, gentamicin, and tobramycin concentrations in tears and in vitro MICs for 90% of test organisms.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:8

    Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Radioimmunoassay; Spectrometry, Fluorescence; Tears; Tobramycin

1990
Corneal epithelial wound healing: a tissue culture assay on the effect of antibiotics.
    Current eye research, 1990, Volume: 9, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Cell Movement; Cells, Cultured; Cornea; Epithelium; Gentamicins; Ofloxacin; Rabbits; Time Factors; Tobramycin; Wound Healing

1990
In vitro activity of fleroxacin and 6 other antimicrobials against Acinetobacter anitratus.
    Chemotherapy, 1989, Volume: 35, Issue:5

    Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Enoxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Ofloxacin; Tobramycin

1989
Assessment of the in vitro and in vivo activity of ciprofloxacin measured against current standards of therapy.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:5

    Topics: Ampicillin; Animals; Azlocillin; Blood; Ciprofloxacin; Escherichia coli; Humans; In Vitro Techniques; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Sisomicin; Tobramycin

1985
Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefazolin; Cephalosporins; Clinical Trials as Topic; Corneal Ulcer; Double-Blind Method; Drug Therapy, Combination; Eye Infections, Bacterial; Humans; Ofloxacin; Randomized Controlled Trials as Topic; Tobramycin

1996
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains.
    Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin

1996
Pharmacodynamic parameters of ofloxacin, tobramycin and ceftriaxone and their effect on the biological properties of salmonellae.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Coloring Agents; Congo Red; Microbial Sensitivity Tests; Ofloxacin; Salmonella; Salmonella enteritidis; Salmonella Phages; Salmonella typhimurium; Tobramycin

1997
[Corneal penetration of various aminoglycosides and quinolones].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 213, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Aqueous Humor; Cataract Extraction; Ciprofloxacin; Contact Lenses; Cornea; Dose-Response Relationship, Drug; Drug Delivery Systems; Gentamicins; Humans; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Tobramycin

1998
Molecular characterization of epidemic multiresistant Staphylococcus haemolyticus isolates.
    Diagnostic microbiology and infectious disease, 1998, Volume: 32, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Cefazolin; Cefmetazole; Cross Infection; DNA Restriction Enzymes; Drug Resistance, Microbial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Gentamicins; Hospital Bed Capacity, 500 and over; Humans; Imipenem; Infant, Newborn; Microbial Sensitivity Tests; Neonatal Nursing; Nursing Staff, Hospital; Ofloxacin; Oxacillin; Phylogeny; Staphylococcal Infections; Staphylococcus; Tobramycin; Vancomycin

1998
Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones.
    Ophthalmology, 2000, Volume: 107, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cornea; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bacterial; Florida; Gentamicins; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies; Tobramycin

2000
[Effect of ofloxacin, pefloxacin, and tobramycin on the hydrophobicity of Klebsiella pneumoniae].
    Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne, 1999, Volume: 48, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dose-Response Relationship, Drug; Klebsiella pneumoniae; Ofloxacin; Pefloxacin; Tobramycin

1999
Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials.
    Journal of bacteriology, 2001, Volume: 183, Issue:23

    Topics: Animals; Biofilms; Carbenicillin; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Ofloxacin; Peracetic Acid; Plankton; Pseudomonas aeruginosa; Tobramycin

2001
Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2000, Volume: 6, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacterial Proteins; Ceftazidime; Cephalosporins; Clarithromycin; Clindamycin; Erythromycin; In Vitro Techniques; Josamycin; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Oleandomycin; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Time Factors; Tobramycin

2000
The effectiveness of tobramycin and Ocuflox in a prophylaxis model of Staphylococcus keratitis.
    Current eye research, 2001, Volume: 23, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Colony Count, Microbial; Corneal Stroma; Eye Infections, Bacterial; Keratitis; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin

2001
Delivery of antibiotics to the eye using a positively charged polysaccharide as vehicle.
    AAPS pharmSci, 2001, Volume: 3, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Biological Availability; Biopolymers; Chitin; Chitosan; Dosage Forms; Drug Delivery Systems; Eye; Male; Molecular Structure; Molecular Weight; Ofloxacin; Rabbits; Solubility; Solutions; Tears; Time Factors; Tobramycin; Treatment Outcome

2001
A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics.
    Current eye research, 2003, Volume: 27, Issue:5

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cornea; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Glucocorticoids; Mice; Mice, Inbred C57BL; Ofloxacin; Prednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2003
Rapid colorimetric assay for antimicrobial susceptibility testing of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Colony Count, Microbial; Colorimetry; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Reproducibility of Results; Tetrazolium Salts; Tobramycin

2004
In vitro activity of parenteral Beta-lactams, levofloxacin and tobramycin alone or in combination against extended-spectrum Beta-lactamase producing Klebsiella pneumoniae.
    International journal of antimicrobial agents, 2004, Volume: 24, Issue:1

    Topics: beta-Lactamases; beta-Lactams; Drug Therapy, Combination; Infusions, Parenteral; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tobramycin

2004
Severe corneal edema after temporomandibular joint reconstruction: report of a case.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2004, Volume: 62, Issue:10

    Topics: Adolescent; Ankylosis; Anti-Infective Agents; Corneal Edema; Female; Humans; Ofloxacin; Postoperative Complications; Saline Solution, Hypertonic; Temporomandibular Joint Disorders; Tobramycin

2004
Postoperative Corynebacterium macginleyi endophthalmitis.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:11

    Topics: Aged; Aqueous Humor; Bacterial Typing Techniques; Cataract Extraction; Chronic Disease; Corynebacterium; Corynebacterium Infections; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial; Gene Amplification; Humans; Lens Implantation, Intraocular; Male; Ofloxacin; Polymerase Chain Reaction; Postoperative Complications; Tobramycin; Vancomycin; Vitreous Body

2004
In vitro efficacy of the successive or staggered use of eardrops.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2006, Volume: 263, Issue:5

    Topics: Acetic Acid; Adjuvants, Pharmaceutic; Administration, Topical; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Dexamethasone; Drug Administration Schedule; Escherichia coli; Glucocorticoids; Humans; Microbial Sensitivity Tests; Ofloxacin; Otitis Media, Suppurative; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin

2006
Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Anti-Bacterial Agents; Azithromycin; Ceftazidime; Colistin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins; Tobramycin

2006
Moxifloxacin for bacterial keratitis.
    Ophthalmology, 2008, Volume: 115, Issue:6

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Cefazolin; Cornea; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Fluoroquinolones; Humans; Moxifloxacin; Ofloxacin; Quinolines; Randomized Controlled Trials as Topic; Tobramycin; Treatment Outcome

2008
[Bacterial corneal ulcer treated with intrastromal antibiotic. Experimental model in vivo].
    Archivos de la Sociedad Espanola de Oftalmologia, 2009, Volume: 84, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cornea; Corneal Stroma; Corneal Ulcer; Data Interpretation, Statistical; Disease Models, Animal; Female; Gentamicins; Ofloxacin; Prospective Studies; Pseudomonas Infections; Rabbits; Tobramycin; Treatment Outcome

2009
Bilateral acanthamoeba keratitis after orthokeratology.
    Cornea, 2009, Volume: 28, Issue:3

    Topics: Acanthamoeba Keratitis; Biguanides; Contact Lenses, Extended-Wear; Drug Therapy, Combination; Female; Functional Laterality; Humans; Levofloxacin; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult

2009
Efficacy of aerosol MP-376, a levofloxacin inhalation solution, in models of mouse lung infection due to Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Aztreonam; Disease Models, Animal; Female; Levofloxacin; Lung Diseases; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2009
[Analysis on the susceptibility of fusidic acid for common gram positive bacteria].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2009, Volume: 45, Issue:5

    Topics: Anti-Bacterial Agents; Fusidic Acid; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus; Tobramycin; Vancomycin

2009
Bilateral acanthamoeba keratitis after orthokeratology.
    Cornea, 2010, Volume: 29, Issue:6

    Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Biguanides; Drug Therapy, Combination; Escherichia coli Infections; Female; Functional Laterality; Humans; Levofloxacin; Microscopy, Phase-Contrast; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult

2010
Post-antibiotic effect of levofloxacin and tobramycin alone or in combination with cefepime against Pseudomonas aeruginosa.
    Chemotherapy, 2009, Volume: 55, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Time Factors; Tobramycin

2009
Corneal infiltrates after corneal collagen cross-linking.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2010, Volume: 26, Issue:8

    Topics: Adult; Collagen; Corneal Diseases; Corneal Stroma; Cross-Linking Reagents; Drug Therapy, Combination; Female; Humans; Keratoconus; Ofloxacin; Photosensitizing Agents; Postoperative Complications; Riboflavin; Tobramycin; Ultraviolet Rays

2010
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models.
    Acta ophthalmologica, 2010, Volume: 88, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Corneal Ulcer; Disease Models, Animal; Drug Resistance, Bacterial; Eye Infections, Bacterial; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin; Vancomycin

2010
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
    Surgical infections, 2010, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin

2010
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections.
    FEMS immunology and medical microbiology, 2011, Volume: 61, Issue:2

    Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Epithelial Cells; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Levofloxacin; Ofloxacin; Pneumonia; Tobramycin

2011
In vitro kinetics of delivery of tobramycin and ofloxacin from osmotic hydro gel expanders.
    International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:7

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Delivery Systems; Fluorescence Polarization Immunoassay; Hydrogels; Kinetics; Methylmethacrylate; Ofloxacin; Osmosis; Povidone; Solubility; Solutions; Tobramycin

2011
[Hydrogelexpander as drug delivery system for antibiotics].
    Klinische Monatsblatter fur Augenheilkunde, 2012, Volume: 229, Issue:2

    Topics: Administration, Ophthalmic; Algorithms; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug Carriers; Drug Delivery Systems; Fluorescence Polarization Immunoassay; Humans; Hydrogels; Infant, Newborn; Metabolic Clearance Rate; Ofloxacin; Surgical Wound Infection; Tobramycin

2012
Lack of significant variability among different methods for calculating antimicrobial days of therapy.
    Infection control and hospital epidemiology, 2012, Volume: 33, Issue:4

    Topics: Adult; Anti-Infective Agents; Ceftriaxone; Drug Dosage Calculations; Humans; Kidney Diseases; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Time Factors; Tobramycin; Vancomycin

2012
Mutant prevention concentration of colistin alone and in combination with levofloxacin or tobramycin against multidrug-resistant Acinetobacter baumannii.
    International journal of antimicrobial agents, 2012, Volume: 40, Issue:5

    Topics: Acinetobacter baumannii; Colistin; Drug Interactions; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Selection, Genetic; Tobramycin

2012
[The changes of ocular bacterial isolates and in vitro antimicrobial susceptibility in the past six years].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:6

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Eye; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus epidermidis; Tobramycin

2012
Bilateral orbital preseptal cellulitis after combined adenotonsillectomy and strabismus surgery--case report and pathogenetic hypothesis.
    International journal of pediatric otorhinolaryngology, 2013, Volume: 77, Issue:7

    Topics: Adenoidectomy; Anti-Bacterial Agents; Ceftriaxone; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Male; Ofloxacin; Ophthalmologic Surgical Procedures; Orbital Cellulitis; Strabismus; Tobramycin; Tonsillectomy; Treatment Outcome

2013
Canaliculitis due to Gemella haemolysans in a single isolate.
    Archivos de la Sociedad Espanola de Oftalmologia, 2018, Volume: 93, Issue:6

    Topics: Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Canaliculitis; Combined Modality Therapy; Curettage; Dexamethasone; Female; Gemella; Gram-Positive Bacterial Infections; Humans; Ofloxacin; Tobramycin

2018
Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Cations; Cell Line; Dog Diseases; Dogs; Drug Resistance, Microbial; Eye; Eye Infections, Bacterial; Gentamicins; Humans; Hydrogen Peroxide; Mice; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Steroids; Tobramycin; Veterinary Drugs

2018