ofloxacin and tigecycline

ofloxacin has been researched along with tigecycline in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (55.00)29.6817
2010's9 (45.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Gikas, A; Psaroulaki, A; Spyridaki, I; Tselentis, Y; Vranakis, I1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Garrison, MW; Nuemiller, JJ1
Dowzicky, M; Kuti, JL; Nicolau, DP1
May, T1
Bergallo, C; Cooper, CA; Dartois, N; Dukart, G; Gandjini, H; Jasovich, A; Mallick, R; Oliva, ME; Tanaseanu, C; Teglia, O1
Gea-Banacloche, JC; Green, O; Murray, P1
Bergallo, C; Cooper, A; de Wouters, L; Dukart, G; Jasovich, A; Lentnek, A; Mallick, R; Oliva, ME; Teglia, O; Zlocowski, JC1
Castaing, N; Cooper, A; Dartois, N; Gandjini, H1
Calistru, PI; Castaing, N; Chernyak, V; Cooper, CA; Dartois, N; Gandjini, H; Milutinovic, S; Strausz, J; Tanaseanu, C; Zolubas, M1
Hsueh, PR; Lee, PI; Yang, JC1
Ozbek, B; Sentürk, A1
Baltch, AL; Bopp, LH; Michelsen, PB; Ritz, WJ; Smith, RP1
Drokov, MIu; Galstian, GM; Giliazitdinova, EA; Karpova, TI; Katrysh, SA; Kliasova, GA; Marakusha, BI; Tartakovskiĭ, IS1
Babinchak, T; Cooper, AC; Gardiner, D; Ramirez, JA; Wiemken, T1
Debata, NK; Jena, J; Sahoo, RK; Subudhi, E1

Reviews

1 review(s) available for ofloxacin and tigecycline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for ofloxacin and tigecycline

ArticleYear
Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia.
    Diagnostic microbiology and infectious disease, 2008, Volume: 61, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Female; Gram-Negative Bacterial Infections; Haemophilus Infections; Humans; Levofloxacin; Liver Function Tests; Male; Middle Aged; Minocycline; Ofloxacin; Pneumococcal Infections; Pneumonia, Bacterial; Tigecycline; Treatment Outcome

2008
Safety and efficacy of intravenous tigecycline in treatment of community-acquired pneumonia: results from a double-blind randomized phase 3 comparison study with levofloxacin.
    Diagnostic microbiology and infectious disease, 2009, Volume: 63, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Female; Haemophilus influenzae; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Moraxella catarrhalis; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Streptococcus pneumoniae; Tigecycline; Treatment Outcome

2009
Tigecycline versus levofloxacin for the treatment of community-acquired pneumonia: European experience.
    Journal of chemotherapy (Florence, Italy), 2008, Volume: 20 Suppl 1

    Topics: Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; International Agencies; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Safety; Tigecycline; Treatment Outcome

2008
Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia.
    BMC pulmonary medicine, 2009, Sep-09, Volume: 9

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Minocycline; Nausea; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Severity of Illness Index; Tigecycline; Treatment Outcome; Vomiting; Young Adult

2009
Switch therapy in hospitalized patients with community-acquired pneumonia: tigecycline vs. levofloxacin.
    BMC infectious diseases, 2012, Jul-19, Volume: 12

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Tigecycline; Treatment Outcome

2012

Other Studies

14 other study(ies) available for ofloxacin and tigecycline

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Bacteriostatic and bactericidal activities of tigecycline against Coxiella burnetii and comparison with those of six other antibiotics.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Coxiella burnetii; Humans; Microbial Sensitivity Tests; Minocycline; Q Fever; Tigecycline; Vero Cells

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vitro activity of tigecycline against quinolone-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.
    International journal of antimicrobial agents, 2007, Volume: 29, Issue:2

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecalis; Methicillin Resistance; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Staphylococcus aureus; Streptococcus pneumoniae; Tigecycline; Vancomycin Resistance

2007
A pharmacodynamic simulation to assess tigecycline efficacy for hospital-acquired pneumonia compared with other common intravenous antibiotics.
    Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; Cross Infection; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Models, Biological; Monte Carlo Method; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Tigecycline

2008
[New antibiotics].
    La Revue de medecine interne, 2008, Volume: 29 Suppl 1

    Topics: Anti-Bacterial Agents; beta-Lactams; Daptomycin; Ertapenem; Humans; Ketolides; Minocycline; Ofloxacin; Tigecycline; Virginiamycin

2008
Sepsis caused by Elizabethkingia miricola successfully treated with tigecycline and levofloxacin.
    Diagnostic microbiology and infectious disease, 2008, Volume: 62, Issue:4

    Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Lymphoma, Mantle-Cell; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Sepsis; Stem Cell Transplantation; Tigecycline

2008
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010, Volume: 29, Issue:11

    Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline

2010
Postantibiotic effects of tigecycline, colistin sulfate, and levofloxacin alone or tigecycline-colistin sulfate and tigecycline-levofloxacin combinations against Acinetobacter baumannii.
    Chemotherapy, 2010, Volume: 56, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Thienamycins; Tigecycline

2010
Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages.
    Diagnostic microbiology and infectious disease, 2011, Volume: 69, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Load; Bacterial Typing Techniques; Erythromycin; Humans; Legionella; Legionellosis; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Microbial Viability; Minocycline; Ofloxacin; Serotyping; Tigecycline; Time Factors

2011
[A case of legionellesis pneumonia verified by isolation of Legionella pneumophila serogroup 1 from bronchoalveolar lavage fluid treated with levofloxacine and tigecycline].
    Terapevticheskii arkhiv, 2011, Volume: 83, Issue:7

    Topics: Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Drug Therapy, Combination; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Tigecycline; Treatment Outcome

2011
Phylogenetic study of metallo-β-lactamase producing multidrug resistant Pseudomonas aeruginosa isolates from burn patients.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8

    Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Burns; Ceftazidime; Ceftriaxone; Cilastatin; Clavulanic Acid; Colistin; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Multiple, Bacterial; Genetic Variation; Humans; Imipenem; Minocycline; Netilmicin; Ofloxacin; Phylogeny; Polymerase Chain Reaction; Pseudomonas aeruginosa; Tigecycline

2015