ofloxacin and streptomycin

ofloxacin has been researched along with streptomycin in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.56)18.7374
1990's11 (14.10)18.2507
2000's19 (24.36)29.6817
2010's43 (55.13)24.3611
2020's3 (3.85)2.80

Authors

AuthorsStudies
Apiwattanakul, N; Endou, H; Jariyawat, S; Kanai, Y; Sekine, T; Sophasan, S; Takeda, M1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
Lombardo, F; Obach, RS; Waters, NJ1
Hansen, S; Lewis, K; Vulić, M1
Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW1
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M1
Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A1
Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Mima, T; Schweizer, HP1
Goswami, M; Jawali, N1
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ1
Dubey, A; Srivastava, SD; Srivastava, SK1
Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Senadeera, SP; Sureram, S1
Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T1
Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG1
Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH1
Ambady, A; Guptha, S; Hegde, N; Hosagrahara, VP; Humnabadkar, V; Kaur, P; Mahadevaswamy, J; Nagalapur, K; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, S; Ramachandran, V; Rudrapatna, SS; Sambandamurthy, VK; Sharma, S; Shirude, PS1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P1
Aree, T; Ganihigama, DU; Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Sangher, S; Sureram, S1
Bowornwiriyapan, K; Daengrot, C; Phongpaichit, S; Rukachaisirikul, V; Sakayaroj, J; Tansakul, C; Thongpanchang, T1
Chen, K; Ge, Z; Huang, Y; Ji, Q; Liao, F; Liu, X; Wu, H; Yang, X; Yuan, L1
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bowornwiriyapan, K; Duangjai, A; Muanprasat, C; Phainuphong, P; Phongpaichit, S; Rukachaisirikul, V; Saithong, S; Sakayaroj, J; Srimaroeng, C1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H1
Bera, S; Mondal, D1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K1
Blanco, C; Demay, F; Dhalluin, A; Ermel, G; Georgeault, S; Giard, JC; Gillet, R; Gomes Von Borowski, R; Hanh Le, H; Jean, M; Radigue, R; Thepaut, M; Trautwetter, A; Tresse, C; van de Weghe, P1
Kwan, SY; Lee, J; Wong, PC; Yew, WW1
Lang, R; Rubinstein, E; Shasha, B1
Chau, PY; Khin, MA; Kwan, SY; Ma, WK; Yew, WW1
Acar, S; Ceyhan, M; Korten, V; Mert, A; Ovünç, K; Ulaş, T1
Saito, H; Tsukamura, M; Yasuda, Y; Yoshii, S1
Berning, SE; Elliott, AM; Iseman, MD; Peloquin, CA1
Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H1
Furukawa, T; Komachi, H; Nagai, R; Saito, Y; Takewaki, S; Uchihara, T1
Kumar, D; Srivastava, BS; Srivastava, R; Subramaniam, P1
Furusawa, M; Kondo, T; Onodera, Y; Tanabe, K1
Colosetti, P; Finance, C; Marchal, S; Merlin, JL1
Bajaksouzian, S; Jacobs, MR; Joloba, ML1
Deb, DK; Srivastava, BS; Srivastava, KK; Srivastava, R1
Han, L; Lee, DH; Lee, WC; Mitnick, CD; Park, SK; Seung, KJ1
Nakagawa, T; Ogawa, K; Taga, S; Tano, M1
Avramopoulos, I; Falagas, ME; Rafailidis, PI; Sapkas, G1
But, AD; Ersoy, Y; Sonmez, E; Tevfik, MR1
Deziel, MR; Drusano, GL; Liu, W; Louie, A1
Conde, MB; Dorman, SE; Guerra, RL; Mello, FC; Muzy-de-Souza, GR; Szklo, A1
Khaki, A; Khaki, AA; Nikmanesh, M; Nouri, M; Novin, MG; Sanati, E1
Chen, YC; Ho, CC; Hu, FC; Luh, KT; Yang, PC; Yu, CJ1
Agarwal, A; Arora, A; Kumar, S1
Chang, KC; Leung, CC; Tam, CM; Yew, WW1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA1
Connolly, C; Friedland, G; Gandhi, N; Moodley, P; Shah, NS; Sturm, AW; Tayob, N; Zetola, N1
Hsueh, PR; Huang, YT; Lai, CC; Liao, CH; Tan, CK1
Cho, EH; Jeon, CY; Kang, H; Kim, H; Kim, M; Murray, MB; Park, YK1
Badri, T; Belghith, I; Benmously, R; Mokhtar, I; Zaiem, A1
Gachkar, L; Hajilooi, M; Hashemi, SH; Janbakhsh, A; Keramat, F; Mahjub, H; Majzoobi, MM; Mamani, M1
Ikeda, T; Kobayashi, K; Yano, S1
Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J1
Mehrani, M; Mortaz-Hejri, S; Sadeghipour, P; Yousefi-Nooraie, R1
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y1
Choe, KH; Chung, GT; Hwang, SC; Jnawali, HN; Kim, H; Lee, YS; Park, YK; Ryoo, S1
Adnan, AS; Afridi, AK; Ahadi, A; Ahmad, I; Ahmad, N; Basit, A; Haq, Iu; Javaid, A; Khan, AH; Shah, SS; Syed Sulaiman, SA1
Liu, B; Pang, Y; Wang, Y; Zhang, D1
Choi, SB; Jo, KW; Jung, H; Kang, MR; Lee, YS; Shim, TS1
Abbas, M; Ehtisham-Ul-Haque, S; Javed, I; Javed, MT; Mahmood, Z; Riaz, M; Shahid, M1
Birčák, E; Hadariová, L; Krajčovič, J; Schwartzbach, SD; Vesteg, M1
Ahmad, N; Javaid, A; Khan, AH; Shaheen, Z1
Campanerut-Sá, PAZ; Cardoso, RF; Ghiraldi-Lopes, LD; Meneguello, JE; Pavan, FR; Scodro, RBL; Siqueira, VLD; Svidzinski, TIE; Teixeira, JJV1
Chen, YH; Huang, CH; Kuo, CY; Lu, PL; Wang, WH1
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR1
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T1
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F1
Guo, Y; Liu, H; Sha, W; Shen, H; Shen, X; Tan, G; Wu, X; Wu, Z; Yang, J; Yu, F1
Guo, Y; Huang, C; Sha, W; Tan, G; Wu, X; Yang, J; Yu, F1

Reviews

4 review(s) available for ofloxacin and streptomycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Antibiotics for treating human brucellosis.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Anti-Bacterial Agents; Brucellosis; Ciprofloxacin; Doxycycline; Humans; Ofloxacin; Randomized Controlled Trials as Topic; Rifampin; Streptomycin

2012
Systematic review on the proteomic profile of Mycobacterium tuberculosis exposed to drugs.
    Proteomics. Clinical applications, 2017, Volume: 11, Issue:11-12

    Topics: Anti-Bacterial Agents; Electrophoresis, Gel, Two-Dimensional; Fluoroquinolones; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Proteome; Proteomics; Streptomycin

2017

Trials

5 trial(s) available for ofloxacin and streptomycin

ArticleYear
A controlled study of rifabutin and an uncontrolled study of ofloxacin in the retreatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin and rifampicin. Hong Kong Chest Service/British Medical Research Council.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1992, Volume: 73, Issue:1

    Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Sputum; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary

1992
Comparison of three different combination therapies in the treatment of human brucellosis.
    Tropical doctor, 2005, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Brucella; Brucellosis; Doxycycline; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Ofloxacin; Rifampin; Streptomycin; Treatment Outcome

2005
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult

2011
Comparison of doxycycline-streptomycin, doxycycline-rifampin, and ofloxacin-rifampin in the treatment of brucellosis: a randomized clinical trial.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2012, Volume: 16, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Doxycycline; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Rifampin; Streptomycin; Treatment Outcome; Young Adult

2012
Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:9

    Topics: Adult; Antitubercular Agents; Coinfection; Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophilia; Female; Fever; HIV Infections; Humans; Male; Ofloxacin; Peripheral Nervous System Diseases; Pruritus; Skin Tests; South Africa; Stevens-Johnson Syndrome; Streptomycin; Tuberculosis

2012

Other Studies

69 other study(ies) available for ofloxacin and streptomycin

ArticleYear
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Animals; Anion Transport Proteins; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Cell Survival; Cephaloridine; Cephalosporins; In Vitro Techniques; Kidney; Kinetics; Oocytes; p-Aminohippuric Acid; Penicillin G; Rats; Recombinant Proteins; Xenopus laevis

1999
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Mutation; Nucleotides; Ofloxacin

2008
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin

2008
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis

2009
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens

2009
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Burkholderia pseudomallei; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Periplasmic Proteins; Quorum Sensing; Singapore; Virulence Factors

2010
N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Acetylcysteine; Anti-Bacterial Agents; Culture Media; Drug Resistance, Bacterial; Expectorants; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests

2010
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin

2010
Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: a new class of biological compounds.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Azetidines; Microbial Sensitivity Tests; Microwaves; Mycobacterium tuberculosis; Triazoles

2011
Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Alkaloids; Antitubercular Agents; Benzylisoquinolines; Drug Resistance, Multiple, Bacterial; Humans; Magnetic Resonance Spectroscopy; Menispermaceae; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Plant Extracts; Plant Roots; Tuberculosis, Multidrug-Resistant

2012
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells

2012
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells

2013
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
    Journal of natural products, 2013, Nov-22, Volume: 76, Issue:11

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells

2013
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pyrazoles; Pyridones; Structure-Activity Relationship

2014
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Antitubercular Agents; Biological Products; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Quinolines; Structure-Activity Relationship

2015
Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138.
    Journal of natural products, 2015, Apr-24, Volume: 78, Issue:4

    Topics: Animals; Antimalarials; Antineoplastic Agents; Biphenyl Compounds; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Penicillium; Plasmodium falciparum; Sesquiterpenes; Soil Microbiology; Sulfides; Thailand; Vero Cells

2015
Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Amides; Antifungal Agents; Aspergillus flavus; Aspergillus fumigatus; Candida albicans; Candida tropicalis; Chitin Synthase; Coumarins; Cryptococcus neoformans; Dose-Response Relationship, Drug; Enzyme Inhibitors; Microbial Sensitivity Tests; Phosphoric Acids; Structure-Activity Relationship

2016
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles

2016
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.
    Journal of natural products, 2016, 06-24, Volume: 79, Issue:6

    Topics: Animals; Aspergillus; Chlorocebus aethiops; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; KB Cells; Lovastatin; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium scrofulaceum; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Soil Microbiology; Thailand; Vero Cells

2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles

2017
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water

2017
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles

2019
Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics.
    Bioorganic & medicinal chemistry, 2019, 11-01, Volume: 27, Issue:21

    Topics: Anti-Bacterial Agents; Cell Line, Tumor; Cell Survival; Drug Design; Drug Synergism; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxadiazoles

2019
Tolerance of ofloxacin in the treatment of pulmonary tuberculosis in presence of hepatic dysfunction.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary

1992
Therapy of experimental murine brucellosis with streptomycin, co-trimoxazole, ciprofloxacin, ofloxacin, pefloxacin, doxycycline, and rifampin.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Administration, Oral; Animals; Brucellosis; Ciprofloxacin; Doxycycline; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Rifampin; Streptomycin; Trimethoprim, Sulfamethoxazole Drug Combination

1992
In-vitro activity of ofloxacin against Mycobacterium tuberculosis and its clinical efficacy in multiply resistant pulmonary tuberculosis.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary

1990
[Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987].
    Mikrobiyoloji bulteni, 1988, Volume: 22, Issue:2

    Topics: Ampicillin Resistance; Anti-Bacterial Agents; Ceftriaxone; Chloramphenicol Resistance; Drug Resistance, Microbial; Dysentery, Bacillary; Humans; Nalidixic Acid; Ofloxacin; Prospective Studies; Serotyping; Shigella; Shigella boydii; Shigella flexneri; Shigella sonnei; Streptomycin; Tetracycline Resistance; Trimethoprim, Sulfamethoxazole Drug Combination; Turkey

1988
[Antituberculosis chemotherapy including ofloxacin in patients with pulmonary tuberculosis not treated previously].
    Kekkaku : [Tuberculosis], 1986, Volume: 61, Issue:1

    Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Ofloxacin; Oxazines; Rifampin; Streptomycin; Tuberculosis, Pulmonary

1986
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1995, Volume: 76, Issue:5

    Topics: Aged; Antitubercular Agents; Chronic Disease; Empyema, Tuberculous; Ethambutol; Humans; Male; Ofloxacin; Pleural Effusion; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant

1995
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1995, Volume: 76, Issue:1

    Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin

1995
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
    Journal of the neurological sciences, 1996, Volume: 143, Issue:1-2

    Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cycloserine; Ethambutol; Humans; Injections, Spinal; Isoniazid; Male; Meningitis; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Ofloxacin; Polymerase Chain Reaction; Rifampin; Streptomycin

1996
beta-Galactosidase reporter system in mycobacteria and its application in rapid antimycobacterial drug screening.
    Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3

    Topics: Anti-Bacterial Agents; Antitubercular Agents; beta-Galactosidase; Escherichia coli; Genes, Reporter; Isoniazid; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Plasmids; Pyrazinamide; Recombinant Proteins; Rifampin; Streptomycin

1997
A conspicuous adaptability to antibiotics in the Escherichia coli mutator strain, dnaQ49.
    FEMS microbiology letters, 1999, Jul-01, Volume: 176, Issue:1

    Topics: Amino Acid Sequence; Ampicillin Resistance; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Escherichia coli; Molecular Sequence Data; Mutation; Ofloxacin; Quinolones; Streptomycin

1999
Influence of the fluoroquinolone ofloxacin on the intrinsic expression of multidrug resistance phenotype in HCT-8 human colon carcinoma cells.
    Oncology research, 1999, Volume: 11, Issue:8

    Topics: Adenocarcinoma; Anti-Bacterial Agents; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Colonic Neoplasms; Daunorubicin; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Multidrug Resistance-Associated Proteins; Ofloxacin; Penicillins; Streptomycin; Tumor Cells, Cultured

1999
Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis.
    Journal of clinical microbiology, 2000, Volume: 38, Issue:10

    Topics: Agar; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin

2000
Bioluminescent Mycobacterium aurum expressing firefly luciferase for rapid and high throughput screening of antimycobacterial drugs in vitro and in infected macrophages.
    Biochemical and biophysical research communications, 2000, Dec-20, Volume: 279, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cell Line; Coleoptera; Fluoroquinolones; Genes, Reporter; Luciferases; Luminescent Measurements; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Recombinant Proteins; Rifampin; Streptomycin; Transfection

2000
Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2004, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Cohort Studies; Cycloserine; Female; Humans; Kanamycin; Korea; Male; Middle Aged; Ofloxacin; Prothionamide; Pyrazinamide; Retrospective Studies; Self Administration; Streptomycin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2004
[The clinical study on efficacy of clarithromycin, levofloxacin, and streptomycin for pulmonary Mycobacterium avium-intracellulare complex infection].
    Kekkaku : [Tuberculosis], 2005, Volume: 80, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Blood Sedimentation; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Ofloxacin; Radiography, Thoracic; Retrospective Studies; Streptomycin

2005
Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates.
    The Journal of infection, 2006, Volume: 52, Issue:2

    Topics: Anti-Bacterial Agents; Biopsy, Fine-Needle; Bone Transplantation; Cycloserine; Discitis; Drug Therapy, Combination; Ethambutol; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Thoracic Vertebrae; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Osteoarticular; Vitamin B 6; Vitamin B Complex

2006
Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Drug Resistance, Bacterial; Humans; Immunocompetence; Levofloxacin; Mice; Microbial Sensitivity Tests; Mutation; Neutropenia; Ofloxacin; Plague; Selection, Genetic; Streptomycin; Thigh; Treatment Outcome; Yersinia pestis

2007
Alternative anti-tuberculosis regimen including ofloxacin for the treatment of patients with hepatic injury.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2007, Volume: 11, Issue:7

    Topics: Antitubercular Agents; Brazil; Cohort Studies; Comorbidity; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Hospitals, Public; Humans; Liver Diseases; Liver Function Tests; Male; Mycobacterium tuberculosis; Odds Ratio; Ofloxacin; Recurrence; Retrospective Studies; Risk Assessment; Severity of Illness Index; Streptomycin; Survival Rate; Treatment Failure; Treatment Outcome; Tuberculosis, Pulmonary; Urban Population

2007
Comparative study of the effects of gentamicin, neomycin, streptomycin and ofloxacin antibiotics on sperm parameters and testis apoptosis in rats.
    Pakistan journal of biological sciences : PJBS, 2008, Jul-01, Volume: 11, Issue:13

    Topics: Animals; Anti-Bacterial Agents; Apoptosis; Gentamicins; Male; Neomycin; Ofloxacin; Organ Size; Rats; Rats, Wistar; Spermatozoa; Streptomycin; Testis

2008
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Jun-01, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercular Agents; Aspartate Aminotransferases; Aza Compounds; Ethambutol; Female; Fluoroquinolones; Hepatic Insufficiency; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Streptomycin; Treatment Outcome; Tuberculosis; Young Adult

2009
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective.
    The Indian journal of tuberculosis, 2009, Volume: 56, Issue:4

    Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular

2009
Streptomycin susceptibility and MDR-TB: can we refine the definition of XDR-TB?
    American journal of respiratory and critical care medicine, 2011, Jan-15, Volume: 183, Issue:2

    Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Microbial Sensitivity Tests; Ofloxacin; Streptomycin; Tuberculosis, Pulmonary

2011
Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; South Africa; Streptomycin

2011
Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Streptomycin; Taiwan; Tuberculosis, Multidrug-Resistant

2011
Clustering of Mycobacterium tuberculosis strains from foreign-born patients in Korea.
    Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 12

    Topics: Antitubercular Agents; Cluster Analysis; DNA Transposable Elements; Emigrants and Immigrants; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Mycobacterium tuberculosis; Ofloxacin; Republic of Korea; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant

2011
[Scrofuloderma with hypersensitivity to rifampicin and pyrazinamide, treated with a combination therapy including ofloxacin].
    Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:4

    Topics: Adult; Antibiotics, Antitubercular; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous

2012
Multidrug-resistant tuberculosis that required 2 years for diagnosis.
    BMJ case reports, 2012, Mar-27, Volume: 2012

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Diagnosis, Differential; Humans; Male; Ofloxacin; Pyrazinamide; Sputum; Streptomycin; Time Factors; Tomography, X-Ray Computed; Tuberculosis, Multidrug-Resistant

2012
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis

2013
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
    Diagnostic microbiology and infectious disease, 2013, Volume: 76, Issue:2

    Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant

2013
Predictors of two months culture conversion in multidrug-resistant tuberculosis: findings from a retrospective cohort study.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Adult; Antitubercular Agents; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Prognosis; Retrospective Studies; Streptomycin; Tuberculosis, Multidrug-Resistant

2014
Rapid molecular screening for multidrug-resistant tuberculosis in a resource-limited region of China.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:10

    Topics: Antitubercular Agents; Bacterial Proteins; China; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genes, Bacterial; Humans; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant

2014
Performance of REBA MTB-XDR to detect extensively drug-resistant tuberculosis in an intermediate-burden country.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2015, Volume: 21, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genes, MDR; Humans; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Predictive Value of Tests; Republic of Korea; Rifampin; Sputum; Streptomycin

2015
Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.
    International journal of immunopathology and pharmacology, 2016, Volume: 29, Issue:3

    Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Streptomycin

2016
An intact plastid genome is essential for the survival of colorless Euglena longa but not Euglena gracilis.
    Current genetics, 2017, Volume: 63, Issue:2

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Chloroplast Proteins; DNA, Chloroplast; Euglena gracilis; Euglena longa; Gene Deletion; Gene Dosage; Genes, Chloroplast; Genome, Plastid; Mutagenesis; Ofloxacin; Plastids; Sequence Homology, Amino Acid; Species Specificity; Streptomycin; Time Factors

2017
Applicability of the World Health Organization recommended new shorter regimen in a multidrug-resistant tuberculosis high burden country.
    The European respiratory journal, 2017, Volume: 49, Issue:1

    Topics: Adult; Antitubercular Agents; Communicable Disease Control; Drug Administration Schedule; Ethambutol; Female; Humans; Infectious Disease Medicine; Male; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Pyrazinamide; Streptomycin; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult

2017
Resistance to first- and second-line antituberculosis drugs in Southern Taiwan: Implications for empirical treatment.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Taiwan

2018
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
    Annals of clinical microbiology and antimicrobials, 2017, Aug-18, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant

2017
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
    Bioinformatics (Oxford, England), 2018, 05-15, Volume: 34, Issue:10

    Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant

2018
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 96

    Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing

2020
Use of Whole-Genome Sequencing to Predict
    Microbiology spectrum, 2022, 04-27, Volume: 10, Issue:2

    Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant

2022
Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 121

    Topics: Amikacin; Antitubercular Agents; China; Drug Resistance; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nucleotides; Ofloxacin; Rifampin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomycin; Tuberculosis, Lymph Node

2022