ofloxacin and pyrazinamide

ofloxacin has been researched along with pyrazinamide in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.17)	18.7374
1990's	9 (14.29)	18.2507
2000's	20 (31.75)	29.6817
2010's	31 (49.21)	24.3611
2020's	1 (1.59)	2.80

Authors

Authors	Studies
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M	1
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ	1
Bocanegra-García, V; García, A; Palma-Nicolás, JP; Rivera, G	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T	1
Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Baskakova, SA; Charushin, VN; Chupakhin, ON; Kravchenko, MA; Rusinov, GL; Skornyakov, SN; Verbitskiy, EV	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Bera, S; Mondal, D	1
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR	1
Kwan, SY; Lee, J; Wong, PC; Yew, WW	1
Heap, BJ	1
Ichiyama, S; Tsukamura, M	1
Alfalla, C; Hewlett, D; Horn, DL; Opal, SM; Peterson, S	1
Hadiarto, M; Hudoyo, A; Tjandra, YA	1
Crowle, AJ; Iseman, MD; Sbarbaro, JA	1
Higgins, K; Maxwell, R; Meador, J; Onorato, IM; Ridzon, R; Weismuller, P	1
Kumar, D; Srivastava, BS; Srivastava, R; Subramaniam, P	1
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE	1
Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE	1
Cheon, SH; Dietze, R; Ellner, JJ; Hise, AG; Landen, K; Palaci, M; Phillips, M; Ribeiro, FC; Song, HY; Vinhas, S; Wallis, RS	1
Bowersox, J	1
Lee, AS; Lim, IH; Tang, LL; Wong, SY	1
Lou, HX; McKaveney, TP; Shullo, MA	1
Dolovich, LR; Holbrook, A; Loeb, M; Papastavros, T; Whitehead, L	1
Bogadel'nikova, IV; Kunichan, AD; Semenova, OV; Sokolova, GB	1
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA	1
Kunichan, AD; Litovchenko, KV; Sokolova, GB; Tsybanev, AA	1
Chierakul, N; Chindavijak, B; Chulavatnatol, S; Klomsawat, D	1
Chen, L; Chen, QL; Yin, JJ	1
Han, L; Lee, DH; Lee, WC; Mitnick, CD; Park, SK; Seung, KJ	1
Gurumurthy, P; Kumar, AK	1
Janulionis, E; Sofer, C; Song, HY; Wallis, RS	1
Hoeppner, VH; Jones, W; Marciniuk, DD; Ward, HA	1
Avramopoulos, I; Falagas, ME; Rafailidis, PI; Sapkas, G	1
Allen, J; Coleman, DJ; Davies, GR; Fourie, B; Kanyok, T; Levin, J; Lienhardt, C; Mitchison, DA; Mthiyane, T; Reddy, C; Rustomjee, R; Sirgel, FA; Sturm, AW	1
Martínez, E; Nam-Cha, S; Puerta, A; Salinas, A	1
Agarwal, A; Arora, A; Kumar, S	1
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A	1
Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM	1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA	1
Desai, VB; Fredrick, JS; Joseph, P; Mohan, NS; Ramachandran, R; Raman, B; Thomas, A; Wares, F	1
Badri, T; Belghith, I; Benmously, R; Mokhtar, I; Zaiem, A	1
Ikeda, T; Kobayashi, K; Yano, S	1
Hassan, G; Kant, S; Parengal, J; Saheer, S	1
Bergmann, JF; Cambau, E; Evans, J; Hoang-Nguyen, DT; Lloret-Linares, C; Lopes, A; Mouly, S; Raskine, L; Sellier, P	1
Choe, KH; Chung, GT; Hwang, SC; Jnawali, HN; Kim, H; Lee, YS; Park, YK; Ryoo, S	1
Ahmad, Z; Grosset, JH; Minkowski, A; Nuermberger, EL; Peloquin, CA; Tyagi, S	1
Chikamatsu, K; Fujita, A; Matsumoto, T; Mitarai, S; Mizuno, K; Ogata, H; Saito, T; Suetake, T; Suzuki, K; Toyota, E	1
Chang, KC; Dheda, K	1
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A	1
Gratz, J; Heysell, SK; Houpt, ER; Kibiki, GS; Kumburu, H; Mpagama, SG; Ndusilo, N; Peloquin, CA; Stroup, S	1
Afridi, AK; Ahmad, I; Ahmad, N; Basit, A; Javaid, A; Khan, AH; Khan, MA; Sulaiman, SA	1
Forsman, LD; Hoffner, S; Hu, Y; Mansjö, M; Werngren, J; Xu, B; Zheng, R; Zheng, X	1
Hosmane, GB; Jain, A; Kushwaha, RA; Prasad, R; Singh, A; Srivastava, R	1
Ahmad, N; Javaid, A; Khan, AH; Shaheen, Z	1
Chen, YH; Huang, CH; Kuo, CY; Lu, PL; Wang, WH	1
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T	1
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM	1

Reviews

5 review(s) available for ofloxacin and pyrazinamide

Article	Year
Recent advances in antitubercular natural products. European journal of medicinal chemistry, 2012, Volume: 49 Topics: Animals; Antitubercular Agents; Biological Products; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Mycobacterium tuberculosis; Tuberculosis	2012
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Insights of synthetic analogues of anti-leprosy agents. Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13 Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship	2019
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis	2021
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis. The Lancet. Infectious diseases, 2010, Volume: 10, Issue:9 Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis	2010

Trials

8 trial(s) available for ofloxacin and pyrazinamide

Article	Year
Limited tolerance of ofloxacin and pyrazinamide prophylaxis against tuberculosis. The New England journal of medicine, 1994, Apr-28, Volume: 330, Issue:17 Topics: Health Personnel; Humans; Occupational Diseases; Ofloxacin; Premedication; Pyrazinamide; Tuberculosis, Multidrug-Resistant	1994
Treatment of multidrug-resistant tuberculosis in Indonesia. Chemotherapy, 1996, Volume: 42 Suppl 3 Topics: Adult; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nausea; Ofloxacin; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant	1996
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica AIDS (London, England), 1997, Volume: 11, Issue:12 Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis	1997
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5 Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary	1998
Disposition of uric acid upon administration of ofloxacin alone and in combination with other anti-tuberculosis drugs. Indian journal of experimental biology, 2004, Volume: 42, Issue:3 Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Humans; Isoniazid; Male; Ofloxacin; Pyrazinamide; Rifampin; Uric Acid	2004
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2008, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Nonlinear Dynamics; Ofloxacin; Pyrazinamide; Quinolines; Rifampin; Sputum	2008
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult	2011
Outcome of standardized treatment for patients with MDR-TB from Tamil Nadu, India. The Indian journal of medical research, 2011, Volume: 133 Topics: Adult; Antibiotics, Antitubercular; Communicable Disease Control; Cycloserine; Directly Observed Therapy; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Ethionamide; Female; Humans; India; Kanamycin; Male; Middle Aged; Ofloxacin; Prospective Studies; Pyrazinamide; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2011

Other Studies

50 other study(ies) available for ofloxacin and pyrazinamide

Article	Year
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis	2009
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells	2012
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides. Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17 Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines. Bioorganic & medicinal chemistry, 2016, 08-15, Volume: 24, Issue:16 Topics: Antitubercular Agents; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium; Pyrimidines	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Tolerance of ofloxacin in the treatment of pulmonary tuberculosis in presence of hepatic dysfunction. International journal of clinical pharmacology research, 1992, Volume: 12, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary	1992
Mycobacterium simiae as a cause of intra-abdominal disease: a case report. Tubercle, 1989, Volume: 70, Issue:3 Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Pyrazinamide; Rifampin	1989
[Antagonistic effect of pyrazinamide against the antituberculosis activity of ofloxacin in mice]. Kekkaku : [Tuberculosis], 1987, Volume: 62, Issue:2 Topics: Animals; Drug Resistance, Microbial; Drug Synergism; Female; Liver; Lung; Mice; Mycobacterium bovis; Ofloxacin; Oxazines; Pyrazinamide	1987
Combined effect of pyrazinamide and ofloxacin within the human macrophage. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1996, Volume: 77, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Drug Interactions; Female; Humans; Macrophages; Male; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide	1996
Asymptomatic hepatitis in persons who received alternative preventive therapy with pyrazinamide and ofloxacin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:6 Topics: Adolescent; Adult; Alanine Transaminase; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Ofloxacin; Pyrazinamide; Tuberculosis, Pulmonary	1997
beta-Galactosidase reporter system in mycobacteria and its application in rapid antimycobacterial drug screening. Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3 Topics: Anti-Bacterial Agents; Antitubercular Agents; beta-Galactosidase; Escherichia coli; Genes, Reporter; Isoniazid; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Plasmids; Pyrazinamide; Recombinant Proteins; Rifampin; Streptomycin	1997
A whole blood bactericidal assay for tuberculosis. The Journal of infectious diseases, 2001, Apr-15, Volume: 183, Issue:8 Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin	2001
CPCRA researchers present OI studies at Vancouver. NIAID AIDS agenda, 1996 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis	1996
Characterization of pyrazinamide and ofloxacin resistance among drug resistant Mycobacterium tuberculosis isolates from Singapore. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2002, Volume: 6, Issue:1 Topics: Amidohydrolases; Anti-Infective Agents; Antitubercular Agents; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Polymerase Chain Reaction; Pyrazinamide; Singapore	2002
Limited tolerability of levofloxacin and pyrazinamide for multidrug-resistant tuberculosis prophylaxis in a solid organ transplant population. Pharmacotherapy, 2002, Volume: 22, Issue:6 Topics: Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Organ Transplantation; Pyrazinamide; Retrospective Studies; Transplantation Immunology; Tuberculosis	2002
Adverse events associated with pyrazinamide and levofloxacin in the treatment of latent multidrug-resistant tuberculosis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Jul-23, Volume: 167, Issue:2 Topics: Adolescent; Adult; Anti-Infective Agents; Antitubercular Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyrazinamide; Tuberculosis, Multidrug-Resistant	2002
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:6 Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2002
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:3 Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis	2002
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:12 Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide	2002
Pharmacokinetics of ofloxacin in drug-resistant tuberculosis. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86, Issue:8 Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Area Under Curve; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Humans; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant	2003
[A study on the clinical efficacy of a combination regimen with levofloxacin and capreomycin in the treatment of multi-drug resistant pulmonary tuberculosis]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2003, Volume: 26, Issue:8 Topics: Adolescent; Adult; Antitubercular Agents; Capreomycin; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2003
Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2004, Volume: 8, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Cohort Studies; Cycloserine; Female; Humans; Kanamycin; Korea; Male; Middle Aged; Ofloxacin; Prothionamide; Pyrazinamide; Retrospective Studies; Self Administration; Streptomycin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2004
Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8 Topics: Anti-Infective Agents; Antitubercular Agents; Area Under Curve; Blood; Cells, Cultured; Clofazimine; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Serum Bactericidal Test	2004
Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2005, Volume: 9, Issue:2 Topics: Capreomycin; Cycloserine; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam	2005
Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates. The Journal of infection, 2006, Volume: 52, Issue:2 Topics: Anti-Bacterial Agents; Biopsy, Fine-Needle; Bone Transplantation; Cycloserine; Discitis; Drug Therapy, Combination; Ethambutol; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Thoracic Vertebrae; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Osteoarticular; Vitamin B 6; Vitamin B Complex	2006
[Renal mass in an HIV-positive elderly patient]. Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2 Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Nephrectomy; Ofloxacin; Pyrazinamide; Tomography, X-Ray Computed; Tuberculosis, Renal	2009
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective. The Indian journal of tuberculosis, 2009, Volume: 56, Issue:4 Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular	2009
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2011
[Scrofuloderma with hypersensitivity to rifampicin and pyrazinamide, treated with a combination therapy including ofloxacin]. Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:4 Topics: Adult; Antibiotics, Antitubercular; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous	2012
Multidrug-resistant tuberculosis that required 2 years for diagnosis. BMJ case reports, 2012, Mar-27, Volume: 2012 Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Diagnosis, Differential; Humans; Male; Ofloxacin; Pyrazinamide; Sputum; Streptomycin; Time Factors; Tomography, X-Ray Computed; Tuberculosis, Multidrug-Resistant	2012
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. BMJ case reports, 2012, May-08, Volume: 2012 Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant	2012
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:1 Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node	2013
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea. Diagnostic microbiology and infectious disease, 2013, Volume: 76, Issue:2 Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant	2013
Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis. American journal of respiratory and critical care medicine, 2013, Jul-01, Volume: 188, Issue:1 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Levofloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Treatment Outcome; Tuberculosis	2013
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis]. Kekkaku : [Tuberculosis], 2013, Volume: 88, Issue:3 Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2013
Rationalizing use of fluoroquinolones and pyrazinamide in the battle against multidrug-resistant tuberculosis. American journal of respiratory and critical care medicine, 2013, Jul-01, Volume: 188, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Female; Fluoroquinolones; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Tuberculosis	2013
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India. Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:9 Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis	2013
Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2 Topics: Adolescent; Adult; Amikacin; Antitubercular Agents; Cycloserine; Ethionamide; Female; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Sputum; Tanzania; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2014
Management and treatment outcomes of MDR-TB: results from a setting with high rates of drug resistance. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:9 Topics: Adolescent; Adult; Antitubercular Agents; Cohort Studies; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pakistan; Pyrazinamide; Treatment Failure; Tuberculosis, Multidrug-Resistant; Young Adult	2015
Determination of MIC Breakpoints for Second-Line Drugs Associated with Clinical Outcomes in Multidrug-Resistant Tuberculosis Treatment in China. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Adolescent; Adult; Aged; Amikacin; Antitubercular Agents; China; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Prospective Studies; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult	2016
Frequency of adverse events observed with second-line drugs among patients treated for multidrug-resistant tuberculosis. The Indian journal of tuberculosis, 2016, Volume: 63, Issue:2 Topics: Adult; Antitubercular Agents; Cohort Studies; Cycloserine; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Humans; Kanamycin; Male; Ofloxacin; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Young Adult	2016
Applicability of the World Health Organization recommended new shorter regimen in a multidrug-resistant tuberculosis high burden country. The European respiratory journal, 2017, Volume: 49, Issue:1 Topics: Adult; Antitubercular Agents; Communicable Disease Control; Drug Administration Schedule; Ethambutol; Female; Humans; Infectious Disease Medicine; Male; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Pyrazinamide; Streptomycin; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult	2017
Resistance to first- and second-line antituberculosis drugs in Southern Taiwan: Implications for empirical treatment. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:1 Topics: Aminosalicylic Acid; Antitubercular Agents; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Taiwan	2018
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data. Bioinformatics (Oxford, England), 2018, 05-15, Volume: 34, Issue:10 Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant	2018
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12 Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant	2018