ofloxacin has been researched along with pipemidic acid in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (80.65) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M | 1 |
| Cecchetti, V; Fravolini, A; Fringuelli, R; Mascellani, G; Pagella, P; Palmioli, M; Segre, G; Terni, P | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Barnett, G; Carbó, M; de la Torre, R; Segura, J | 1 |
| Nishino, T; Obana, Y | 1 |
| Harder, S; Papenburg, A; Staib, AH; Stille, W | 1 |
| Beer, C; Harder, S; Papenburg, A; Shah, PM; Staib, AH; Stille, W | 1 |
| Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL | 2 |
| Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH | 1 |
| Grimm, H | 2 |
| Forth, W | 1 |
| Baldinelli, L; De Santis, S; De Simone, C; Ferrazzi, M; Pugnaloni, L; Sorice, F | 1 |
| Cancet, B; Clave, D; Didier, J; Henry-Ferry, S; Marty, N | 1 |
| Concia, E; Cruciani, M; Monzillo, V; Navarra, A; Tinelli, C | 1 |
| Daguet, GL; Delisle-Mizon, F; Lesage, D; Vergez, P | 1 |
| Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L | 1 |
| Guenounou, M; Kodari, E; Momrikof, V; Ronco, E; Vacheron, F | 1 |
| Hirose, T; Inoue, M; Ito, Y; Kato, H; Mitsuhashi, S; Okezaki, E | 1 |
| Kawane, H; Niki, Y; Soejima, R; Sumi, M; Umeki, S | 1 |
| Wittenberger, R | 1 |
| Smith, JT | 1 |
| Bryskier, A; Husson, MO; Izard, D; Leclerc, H | 1 |
| Klesel, N; Limbert, M; Seibert, G | 1 |
| Deguchi, K; Fujita, Y; Kishi, H; Niijima, T; Nishimura, Y; Nito, H; Ogawa, N; Ohmori, H; Saito, I; Tanaka, H | 1 |
| Ito, K; Konishi, K; Kosugi, M; Matsubara, Y; Matsunaga, M; Saito, M; Seo, T; Takizawa, Y; Tomizawa, I; Yanagishita, T | 1 |
| Duan, GC; Xi, YL; Zhu, JY | 1 |
| Depta, JP; Pichler, WJ; Schmid, DA | 1 |
4 trial(s) available for ofloxacin and pipemidic acid
| Article | Year |
|---|---|
4-quinolones inhibit biotransformation of caffeine.
Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline | 1988 |
[Ofloxacin versus pipemidic acid and co-trimoxazole].
Topics: Adult; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Humans; Nicotinic Acids; Ofloxacin; Oxazines; Pipemidic Acid; Random Allocation; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 1986 |
[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Clinical Trials as Topic; Double-Blind Method; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged; Nicotinic Acids; Ofloxacin; Oxazines; Pipemidic Acid; Tablets; Urinary Tract Infections | 1984 |
[Comparison of clinical efficacy of ofloxacin COFLX: DL-8280) and pipemidic acid (PPA) in acute infectious diarrhea by a double-blind method. The Japan Research Committee of Ofloxacin, Research Group for Acute Infectious Diarrhea].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Campylobacter Infections; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Dysentery, Bacillary; Escherichia coli Infections; Female; Humans; Male; Middle Aged; Nicotinic Acids; Ofloxacin; Oxazines; Pipemidic Acid | 1984 |
27 other study(ies) available for ofloxacin and pipemidic acid
| Article | Year |
|---|---|
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.
Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Quinolonecarboxylic acids. 2. Synthesis and antibacterial evaluation of 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acids.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pyridones; Spectrophotometry, Infrared; Thiazines | 1987 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens | 2009 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Pharmacokinetic determination of relative potency of quinolone inhibition of caffeine disposition.
Topics: Caffeine; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Male; Models, Biological; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones | 1990 |
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial Sensitivity Tests; Neutropenia; Norfloxacin; Ofloxacin; Pipemidic Acid; Time Factors; Urinary Tract Infections; Uterus | 1989 |
[Gyrase inhibitors modify metabolising processes in the liver].
Topics: Caffeine; Ciprofloxacin; DNA Topoisomerases, Type II; Enoxacin; Humans; Liver; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Topoisomerase II Inhibitors | 1987 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
[In vitro activity of seven gyrase inhibitors of a group of heterocyclic carbonic acids against nonfermenting gram negative rods (nonfermenters)].
Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Aerobic Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas aeruginosa; Quinolines; Topoisomerase II Inhibitors | 1985 |
[Gyrase inhibitor].
Topics: 4-Quinolones; Anti-Bacterial Agents; Bacteria; Cinoxacin; Drug Resistance, Microbial; Humans; Nalidixic Acid; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1985 |
Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis.
Topics: Adult; Anti-Infective Agents; DNA; Humans; In Vitro Techniques; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Piromidic Acid | 1986 |
[In vitro activity of new quinolones against nonfermenters and references to sensitivity tests].
Topics: Acinetobacter; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Immunodiffusion; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas | 1986 |
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Enoxacin; Female; Humans; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Peptides, Cyclic; Pipemidic Acid; Rifampin; Tetracycline; Tetracycline Resistance; Urinary Tract Infections; Vancomycin; Virginiamycin | 1988 |
Antibacterial activity after a single-dose of norfloxacin, ofloxacin and pipemidic acid detected in urine of volunteers.
Topics: Adult; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella; Male; Nicotinic Acids; Norfloxacin; Ofloxacin; Pipemidic Acid; Proteus mirabilis; Pseudomonas aeruginosa; Time Factors | 1988 |
[Comparison of the in vitro activity of 6 quinolones on Pseudomonas sp].
Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Pseudomonas; Pseudomonas aeruginosa; Quinolines | 1985 |
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Pipemidic Acid; Proteus; Providencia; Urinary Tract Infections | 1988 |
[Modulation by quinolones of the in vitro proliferative response of splenic cells of the mouse and IL 1 production].
Topics: Animals; Anti-Infective Agents; Cell Division; Cells, Cultured; Ciprofloxacin; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred DBA; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Spleen | 1987 |
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones | 1987 |
New synthetic quinolone antibacterial agents and serum concentration of theophylline.
Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline | 1987 |
Frequency and expression of mutational resistance to the 4-quinolone antibacterials.
Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1986 |
Ofloxacin: antibacterial activity, induction of resistance and killing curves.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid | 1985 |
Comparison of the antibacterial in vitro and in vivo activity of ofloxacin (HOE 280 DL 8280) and nalidixic acid analogues.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Drug Resistance, Microbial; Lactams; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid | 1983 |
[Study on the molecular mechanism of quinolone resistance in Shigellae spp].
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pipemidic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Quinolones; Shigella | 2004 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |