ofloxacin has been researched along with pefloxacin in 189 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (46.56) | 18.7374 |
| 1990's | 64 (33.86) | 18.2507 |
| 2000's | 24 (12.70) | 29.6817 |
| 2010's | 10 (5.29) | 24.3611 |
| 2020's | 3 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ | 1 |
| Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M | 1 |
| Domagala, JM; Heifetz, CL; Mich, TF; Nichols, JB | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chhasatia, MR; Gandhi, DS; Patel, MN | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ | 1 |
| Borsa-Lebas, F; Etienne, I; Fillastre, JP; Gy, C; Humbert, G; Leroy, A | 3 |
| Rahal, K | 1 |
| Chelfi, A; Liassine, N; Rahal, K | 1 |
| Jabarit-Aldighieri, N; Raoult, D; Torres, H | 1 |
| Chidiac, C; Mouton, Y; Senneville, E | 1 |
| Audisio, F; De Bandt, M; Hayem, G; Jorgensen, C; Kahn, MF; Meyer, O; Palazzo, E; Ribard, P | 1 |
| Dailloux, M; Villemain, P | 1 |
| Coste-Burel, M; Espaze, EP; Reynaud, AE; Richet, H | 1 |
| Lang, R; Rubinstein, E; Shasha, B | 1 |
| Cserba, I; Csukás, Z; Sztankov, L | 1 |
| Räisäinen, S; Schildt, R; Syrjälä, H | 1 |
| Byl, B; Jacobs, F; Thys, JP | 1 |
| Grosset, J; Ji, B; Truffot-Pernot, C | 1 |
| Brook, I; Elliott, TB | 1 |
| Glauner, B; Gutmann, L; Vincent, S | 1 |
| Mnatsakanian, VE; Padeĭskaia, EN | 1 |
| McQueen, CA; Queener, SM; Schlüter, G; Way, BM; Williams, GM | 1 |
| Carret, G; Flandrois, JP; Lobry, JR | 1 |
| Janknegt, R | 1 |
| al-Shammary, FJ; Bishop, SJ; Shibl, AM; Shoeb, HA; Tawfik, AF | 1 |
| Boeckk, M; Borner, K; Deppermann, N; Höffken, G; Koeppe, P; Lode, H | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Bailly, S; Fay, M; Gougerot-Pocidalo, MA | 1 |
| Brook, I; Elliott, TB; Ledney, GD | 1 |
| Guenounou, M; Miguères, ML; Ronco, E | 1 |
| Grosset, JH; Guelpa-Lauras, CC; Ji, BH; N'Deli, LN; Perani, EG | 1 |
| Dzúriková, V; Gajdos, M; Krechnáková, A; Krivosíková, G; Oksa, A; Ploczeková, C; Spustová, V | 1 |
| Midtvedt, T | 1 |
| Gaillot, J; Montay, G | 1 |
| Biron, F; Boibieux, A; Peyramond, D; Tigaud, S | 1 |
| Cartel, JL; Chanteau, S; Grosset, JH; N'Deli, L; Perani, E; Roux, J | 1 |
| Dameron, G; Dournon, E; Pocidalo, JJ; Rajagopalan-Levasseur, P; Vilde, JL | 1 |
| Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| Glupczynski, Y; Grenier, P; Pierard, D; Van der Auwera, P | 1 |
| Aubert, G; Denis, M; Dorche, G; Loboguerrero, M; Lucht, F; Puech, C | 1 |
| Bernard, E; Dellamonica, P; Drugeon, HB; Etesse, H; Garraffo, R | 1 |
| Akalin, HE; Akyön, Y; Diker, S; Gür, D; Hasçelik, G | 1 |
| Aravantinos, D; Gazis, J; Giamarellou, H; Kolokythas, E; Petrikkos, G; Sfikakis, P | 1 |
| Fong, IW | 1 |
| Douchain, F; Guillot, M; Jehanne, M; Lenoir, G; Menkès, CJ; Pertuiset, E | 1 |
| Antinori, A; Fantoni, M; Federico, G; Nervo, P; Pallavicini, F | 1 |
| Baca, OG; Raoult, D; Yeaman, MR | 1 |
| Dailloux, M; Henry, C; Petitpain, N; Weber, M | 1 |
| Cocuzza, G; Mineo, E; Muschiato, A; Neri, MG; Pessina, A | 1 |
| Dewachter, P; Dopff, C; Dureux, JB; Phelisse, F; Tronel, H; Voiriot, P; Weber, M | 1 |
| Kazmierczak, A; Nordmann, P; Pechinot, A | 1 |
| Shah, PM | 2 |
| Antinori, A; Fantoni, M; Nervo, P; Pallavicini, F; Tamburrini, E | 1 |
| Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC | 1 |
| Neu, HC | 1 |
| Hooper, DC; Wolfson, JS | 1 |
| Baur, C; Davies, BI; Maesen, FP; Teengs, JP | 2 |
| Brouwers, JR; Groeneveld, AJ | 1 |
| Edlund, C; Nord, CE | 2 |
| Auckenthaler, R; Michéa-Hamzehpour, M; Pechère, JC | 1 |
| Avesani, V; Delmee, M | 1 |
| Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL | 2 |
| Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH | 1 |
| Baran, R; Brun, P | 1 |
| Baran, R; Juhlin, L | 1 |
| Borner, K; Lode, H | 1 |
| Høiby, N | 1 |
| Bertrand, A; Janbon, F; Jonquet, O; Reynes, J | 1 |
| Beoletto, C; Grosset, JH; Guelpa-Lauras, CC; Perani, EG | 1 |
| Allocati, N; Oliva, B; Renzini, G; Scazzocchio, F; Schippa, S; Selan, L | 1 |
| Cellini, L; Oliva, B; Renzini, G; Scazzocchio, F; Schippa, S; Selan, L | 1 |
| Bauernfeind, A; Gablac, R; Heinrich, B; Petermüller, C | 1 |
| Fass, RJ; Helsel, VL | 1 |
| Davies, S; Sparham, PD; Spencer, RC | 1 |
| Habiyaremye, I; Vandepitte, J; Verbist, L | 1 |
| Pattyn, SR; Van Caekenberghe, DL; Verhoeven, JR | 1 |
| Bébéar, C; Fourche, J; Mormède, M; Texier-Maugein, J | 1 |
| Fay, M; Gougerot-Pocidalo, MA; Roche, Y | 1 |
| Duval, J; Leclercq, R; Soussy, CJ | 1 |
| Armynot du Chatelet, AM; Attisso, MA; Maillols, M; Simeon de Buochberg, M; Zuccarelli, M | 1 |
| Attisso, MA; Dusart, G; Maillols, H; Simeon de Buochberg, M; Zuccarelli, M | 1 |
| de Micco, P; Gevaudan, MJ; Gulian, C; Lagier, P; Mallet, MN; Terriou, P | 1 |
| Bebear, C; de Barbeyrac, B; Quentin, C; Renaudin, H | 1 |
| Denamur, E; Laurans, G; Orfila, J; Suermondt, G | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Dabernat, H; Delmas, C; Lareng, MB | 1 |
| Daguet, GL; Delisle-Mizon, F; Lesage, D; Vergez, P | 1 |
| Bergogne-Berezin, E; Joly-Guillou, ML | 1 |
| Bryskier, A; Devos, J; Dubreuil, L; Romond, C | 1 |
| Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L | 1 |
| Tunçkanat, F; Yuluğ, N | 1 |
| Cattier, B; Gavignet, M; Goudeau, A; Koubaa, N; Quentin, R | 1 |
| Deforges, L; Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| Fisch, A; Forestier, F; Lafaix, C; Meulemans, A; Montay, G; Salvanet, A | 1 |
| Guenounou, M; Kodari, E; Momrikof, V; Ronco, E; Vacheron, F | 1 |
| Descotes, J; Lombard, JY | 1 |
| Bersani, C; Bertoletti, R; Fietta, A; Gialdroni Grassi, G; Santagada, T | 1 |
| Rietbrock, N; Staib, AH | 1 |
| Andrews, JM; Griggs, D; Lister, D; McNulty, CA; Wise, R | 1 |
| Boogaerts, MA; Malbrain, S; Scheers, W; Verwilghen, RL | 1 |
| Dabbs, DJ; Limb, DI; Spencer, RC | 1 |
| Arpi, M; Bentzon, MW; Gahrn-Hansen, B; Søgaard, P | 1 |
| Mazzei, T; Nicoletti, P; Periti, P | 1 |
| Barry, AL; Jones, RN | 1 |
| Wolff, M | 1 |
| Pattyn, SR | 1 |
| Smith, CR | 1 |
| Kawane, H; Niki, Y; Soejima, R; Sumi, M; Umeki, S | 1 |
| Descotes, J; Evreux, JC; Lombard, JY | 1 |
| Baars, AM; van Herwaarden, CL; Vree, TB; Wijnands, WJ | 2 |
| Borner, K; Glatzel, P; Höffken, G; Koeppe, P; Lode, H; Olschewski, P; Prinzing, C; Reimnitz, D; Sievers, B; Wiley, R | 1 |
| Akalin, E; Baykal, M | 1 |
| Etienne, D; Fay, M; Forest, N; Gougerot-Pocidalo, MA; Pocidalo, JJ; Roche, Y | 1 |
| Davies, BI; Maesen, FP | 1 |
| Bryskier, A; Husson, MO; Izard, D; Leclerc, H | 1 |
| Bryskier, A; Chantot, JF | 1 |
| Bryskier, A; Croize, J; Le Noc, P; Robert, J | 1 |
| Meier-Ewert, H; Millott, G; Weil, G | 1 |
| Cavallaro, G; Fresta, M; Furneri, PM; Giammona, G; Micali, N; Puglisi, G | 1 |
| Dellamonica, P; Fabre, R; Meyran, M; Moreau, N; Thabaut, A | 1 |
| Arman, D; Tural, D; Willke, A | 1 |
| Domarle, O; Hayem, G; Pocidalo, JJ; Thuong-Guyot, M | 1 |
| Accorsi, P; Betti, S; D'Antonio, D; Dell'Isola, M; Favalli, C; Fioritoni, G; Iacone, A; Parruti, G; Piccolomini, R; Quaglietta, AM | 1 |
| Iakovlev, VP | 1 |
| Griffiths, NM; Hirst, BH; Simmons, NL | 1 |
| Gaudin, C; Hayem, G; Kahn, MF; Levacher, M; Petit, PX; Pocidalo, JJ | 1 |
| Carret, G; Flandrois, JP; Guerillot, F | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Auckenthaler, R; Peyret, M; Rohner, P | 1 |
| Gabriel, L; Giamarellou, H; Kanellas, D; Kavouklis, E; Petrikkos, G | 1 |
| Fekete, I; Kelentey, BA; Kelentey, BJ; Kozma, J | 1 |
| Carbon, C; Colas-Linhart, N; Dautrey, S; Farinotti, R; Rabbaa, L | 1 |
| Ahmedy, A; Khardori, N; Toama, M; Yassien, M | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Mémin, E; Panteix, G; Revol, A | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Prabhu, S; Rewari, S | 1 |
| Sieb, JP | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
| Gikas, A; Kofterithis, D; Psaroulaki, A; Spyridaki, I; Tselentis, Y | 1 |
| Bosse, D; Kubin, R; Schacht, P | 1 |
| Bagon, JA | 1 |
| Acar, JF; Goldstein, FW; Kitzis, MD; Miegi, M | 1 |
| Antolic, G; Grabnar, I; Kozjek, F; Mrhar, A; Suturkova, LJ | 1 |
| Abd-Allah, AR; Abdel-Aziz, AA; Aly, HA; Hamada, FM; Moustafa, AM | 1 |
| Hostacká, A | 1 |
| Postnikov, SS | 1 |
| Biss, B; Harnicarova, A; Kriska, M; Macekova, L; Tisonova, J; Wawruch, M | 1 |
| Cambourieu, C; Nourry, H; Pouzaud, F; Rat, P; Warnet, JM | 1 |
| Nazhimov, VP; Novichkova, GA; Postnikov, SS; Semykin, SIu | 1 |
| Coban, AY; Durupinar, B | 1 |
| Abalos, RM; Balagon, MV; Cellona, RV; Cruz, EC; Fajardo, TT; Gelber, RH; Villahermosa, LG | 1 |
| Köşem, M; Ozbek, H; Tuncay, I; Unal, O | 1 |
| Kassab, NM; Kedor-Hackmam, ER; Santoro, MI; Singh, AK | 1 |
| Alekseev, VV; Merinova, LK; Merinova, OA; Pivnen', NN; Seimova, IK; Timoshin, VB; Viktorov, DV; Zakharova, IB | 1 |
| Debray, M; Dutot, M; Martin, C; Pouzaud, F; Rat, P; Warnet, JM | 1 |
| Andreeva, I; Rafalsky, V; Rjabkova, E | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Bobrov, VI; Borisov, MM; Ptitsina, SN | 1 |
| Ali, A; Kaushik, D; Madan, J; Sardana, S; Shankar Pandey, R; Sudhakaran Sudheesh, M | 1 |
| Beytemur, O; Gulmez, T; Kaleagasioglu, F; Mutlu, Z; Olcay, E; Olgac, V | 1 |
| Alañón Molina, A; Boras, N; Murillo Pulgarín, JA | 1 |
| Åhman, J; Kahlmeter, G; Matuschek, E; Petersen, A; Sjölund-Karlsson, M; Skov, R; Stegger, M; Torpdahl, M | 1 |
| Gao, Y; Ji, Y; Lin, Y; Lin, Z; Lu, Y; Yang, Y; Zhang, L | 1 |
| Guo, L; Kuang, H; Lei, X; Liu, L; Xu, C; Xu, L | 1 |
| Foroughi, MM; Jahani, S; Moradalizadeh, M; Taherizadeh, M | 1 |
| Ajayi, SO; Kadiri, S; Toki, RA | 1 |
| Mayer, I; Nagy, E | 1 |
| Christmann, D; Daniel, JP; Moulin, B | 1 |
| Iannetta, M; Mineo, E; Neri, MG; Pessina, A | 1 |
16 review(s) available for ofloxacin and pefloxacin
| Article | Year |
|---|---|
Fluoroquinolone derivatives and their anti-tubercular activities.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
[Value of quinolones in the treatment of lower respiratory tract infections caused by intracellular organisms, excluding mycobacteria].
Topics: Anti-Infective Agents; Chlamydia Infections; Ciprofloxacin; Enoxacin; Erythromycin; Humans; In Vitro Techniques; Legionnaires' Disease; Ofloxacin; Pefloxacin; Pneumonia, Mycoplasma | 1992 |
[Sensitivity of Hemophilus strains to fluoroquinolones].
Topics: Drug Resistance, Microbial; Haemophilus; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones | 1991 |
Role of quinolones in the treatment of bronchopulmonary infections, particularly pneumococcal and community-acquired pneumonia.
Topics: Anti-Infective Agents; Bronchitis; Ciprofloxacin; Drug Therapy, Combination; Enoxacin; Humans; Ofloxacin; Pefloxacin; Pneumonia; Pneumonia, Pneumococcal | 1991 |
CAPD peritonitis and fluoroquinolones: a review.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Ofloxacin; Pefloxacin; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1991 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Pharmacokinetics of fluoroquinolones in hepatic failure.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Half-Life; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Pefloxacin | 1990 |
[Joint tolerance of pefloxacin and ofloxacin in children and adolescents with cystic fibrosis].
Topics: Adolescent; Animals; Arthritis; Cartilage, Articular; Child; Cystic Fibrosis; Dogs; Female; Humans; Iatrogenic Disease; Male; Ofloxacin; Pefloxacin; Retrospective Studies; Synovial Fluid | 1989 |
The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.
Topics: Anti-Bacterial Agents; Bacteria; Blood Proteins; Ciprofloxacin; Enoxacin; Fluorine; Humans; Kidney; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding; Quinolines; Urinary Tract Infections | 1985 |
A review on the impact of 4-quinolones on the normal oropharyngeal and intestinal human microflora.
Topics: Ciprofloxacin; Enoxacin; Humans; Intestines; Naphthyridines; Norfloxacin; Ofloxacin; Oropharynx; Oxazines; Pefloxacin; Quinolines | 1988 |
Quinolones.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
[Current status of resistance of bacteria to pefloxacin in hospital units. Cross resistance with ofloxacin and ciprofloxacin. Results of a multicenter study].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Positive Cocci; Hospital Units; In Vitro Techniques; Methicillin Resistance; Ofloxacin; Pefloxacin | 1994 |
[Pharmacokinetics of fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin | 1993 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
[Pharmacokinetics and dose adaptation of ofloxacine, pefloxacine and ciprofloxacine during haemodialysis and continuous ambulatory peritoneal dialysis].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Kidney Failure, Chronic; Ofloxacin; Pefloxacin; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 2004 |
11 trial(s) available for ofloxacin and pefloxacin
| Article | Year |
|---|---|
Role of quinolones in the treatment of bronchopulmonary infections, particularly pneumococcal and community-acquired pneumonia.
Topics: Anti-Infective Agents; Bronchitis; Ciprofloxacin; Drug Therapy, Combination; Enoxacin; Humans; Ofloxacin; Pefloxacin; Pneumonia; Pneumonia, Pneumococcal | 1991 |
Clinical trial of pefloxacin and ofloxacin in the treatment of lepromatous leprosy.
Topics: Adolescent; Adult; Animals; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leprosy, Borderline; Leprosy, Lepromatous; Male; Mice; Mice, Nude; Middle Aged; Mycobacterium leprae; Ofloxacin; Pefloxacin; Random Allocation | 1990 |
Relationships between PGL-1 antigen in serum, tissue and viability of Mycobacterium leprae as determined by mouse footpad assay in multibacillary patients during short-term clinical trial.
Topics: Animals; Antigens, Bacterial; Glycolipids; Humans; Immunoglobulin M; Leprosy, Lepromatous; Mice; Mycobacterium leprae; Ofloxacin; Pefloxacin; Skin | 1990 |
The role of fluoroquinolones in the management of skin, soft tissue, and bone infections.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Clinical Trials as Topic; Dermatitis; Enoxacin; Gram-Negative Bacteria; Humans; Ofloxacin; Osteomyelitis; Pefloxacin | 1989 |
[Diffusion of fluoroquinolones in the aqueous humor and crystalline lens].
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Diffusion; Humans; Lens, Crystalline; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies.
Topics: Adult; Aged; Agranulocytosis; Anti-Infective Agents; Bacteremia; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Feces; Female; Fever; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Neutropenia; Ofloxacin; Pefloxacin | 1994 |
[Effect of ketoprofen on the pharmacokinetics of two fluoroquinolones in males].
Topics: Adult; Drug Combinations; Drug Evaluation; Drug Interactions; Humans; Ketoprofen; Male; Ofloxacin; Pefloxacin; Reference Values | 1993 |
Kinetics of 4-fluoroquinolones permeation into saliva.
Topics: Adult; Anti-Infective Agents; Biological Transport; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Monitoring; Humans; Male; Norfloxacin; Ofloxacin; Pefloxacin; Saliva | 1999 |
[On fluoroquinolones treatment safety in children (clinical, morphological and catamnesis data)].
Topics: Adolescent; Age Factors; Anemia, Aplastic; Anti-Infective Agents; Body Height; Cartilage; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Infant; Joint Diseases; Knee Joint; Male; Ofloxacin; Pefloxacin; Prospective Studies; Treatment Outcome | 2002 |
A clinical trial of pefloxacin and ofloxacin in lepromatous leprosy.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leprosy, Lepromatous; Male; Mycobacterium leprae; Ofloxacin; Pefloxacin; Philippines; Probability; Prospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2004 |
Quinolones for short-term treatment of uncomplicated urinary tract infection.
Topics: 4-Quinolones; Administration, Oral; Adult; Anti-Infective Agents; Bacterial Infections; Female; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nigeria; Ofloxacin; Pefloxacin; Single-Blind Method; Time Factors; Treatment Outcome; Urinary Tract Infections | 1999 |
163 other study(ies) available for ofloxacin and pefloxacin
| Article | Year |
|---|---|
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship | 1992 |
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.
Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity.
Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones.
Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Interaction of drug based binuclear mixed-ligand complexes with DNA.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity | 2009 |
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology | 2010 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of ketoprofen (NSAID) on the pharmacokinetics of pefloxacin and ofloxacin in healthy volunteers.
Topics: Administration, Oral; Adult; Creatinine; Drug Interactions; Half-Life; Humans; Ketoprofen; Male; Ofloxacin; Pefloxacin | 1992 |
[Comparative activities in vitro of 4 quinolones (nalidixic acid, pefloxacin, norfloxacin, ofloxacin) on 13 bacterial species].
Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Species Specificity | 1992 |
[Resistance to new quinolones among the enterobacteria].
Topics: Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Nalidixic Acid; Ofloxacin; Pefloxacin; Recurrence; Urinary Tract Infections | 1992 |
Susceptibility of Rickettsia conorii, R. rickettsii, and Coxiella burnetii to PD 127,391, PD 131,628, pefloxacin, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Coxiella burnetii; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Rickettsia; Rickettsia rickettsii; Viral Plaque Assay | 1992 |
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cystitis; Female; Humans; Male; Middle Aged; Ofloxacin; Pefloxacin; Rupture, Spontaneous; Spondylitis; Tendinopathy; Tendon Injuries | 1992 |
[Bacteriostatic and bactericidal activities of cyclines, macrolides and fluoroquinolones against Chlamydia trachomatis].
Topics: Chlamydia trachomatis; Dose-Response Relationship, Drug; Doxycycline; Erythromycin; Humans; In Vitro Techniques; Minocycline; Ofloxacin; Pefloxacin; Roxithromycin; Spiramycin | 1992 |
[In vitro kinetics of the activity of fusidic acid and fluoroquinolones combinations against staphylococci according to methicillin-resistance phenotype. Implications for the treatment of osteoarticular infections].
Topics: Bone Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fusidic Acid; Humans; In Vitro Techniques; Joint Diseases; Methicillin; Methicillin Resistance; Ofloxacin; Pefloxacin; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
Therapy of experimental murine brucellosis with streptomycin, co-trimoxazole, ciprofloxacin, ofloxacin, pefloxacin, doxycycline, and rifampin.
Topics: Administration, Oral; Animals; Brucellosis; Ciprofloxacin; Doxycycline; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Rifampin; Streptomycin; Trimethoprim, Sulfamethoxazole Drug Combination | 1992 |
In vitro susceptibility of Francisella tularensis to fluoroquinolones and treatment of tularemia with norfloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Francisella tularensis; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Tularemia | 1991 |
Activities of pefloxacin and ofloxacin against mycobacteria: in vitro and mouse experiments.
Topics: Animals; Female; Mice; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Pefloxacin; Tuberculosis | 1991 |
Quinolone therapy in the prevention of mortality after irradiation.
Topics: Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Cobalt Radioisotopes; Female; Gamma Rays; Mice; Ofloxacin; Pefloxacin; Radiation Injuries, Experimental | 1991 |
Lytic effect of two fluoroquinolones, ofloxacin and pefloxacin, on Escherichia coli W7 and its consequences on peptidoglycan composition.
Topics: Bacterial Proteins; Chloramphenicol; Escherichia coli; Magnesium; Microbial Sensitivity Tests; Nephelometry and Turbidimetry; Ofloxacin; Pefloxacin; Peptidoglycan | 1991 |
[Activity of fluoroquinolones studied on a model of suppurative meningoencephalitis caused by Pseudomonas aeruginosa in mice].
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Enoxacin; Meningoencephalitis; Mice; Ofloxacin; Pefloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 1991 |
Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; DNA; DNA Repair; Liver; Norfloxacin; Ofloxacin; Pefloxacin; Phosphorus Radioisotopes; Rats | 1991 |
Biphasic kinetics of bacterial killing by quinolones.
Topics: Colony Count, Microbial; Escherichia coli; Humans; Infant, Newborn; Models, Theoretical; Nalidixic Acid; Ofloxacin; Pefloxacin | 1991 |
Influence of new quinolones on normal immune capabilities.
Topics: Animals; Anti-Infective Agents; Antibody Formation; Ciprofloxacin; Hypersensitivity, Delayed; Immunity, Cellular; Injections, Intramuscular; Male; Mice; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis | 1990 |
Quinolone pharmacokinetics and metabolism.
Topics: Administration, Oral; Anti-Infective Agents; Biological Availability; Biotransformation; Ciprofloxacin; Enoxacin; Fleroxacin; Half-Life; Humans; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
[Effect of quinolones on TNF-alpha production by human monocytes].
Topics: Ciprofloxacin; Cyclic AMP; Dose-Response Relationship, Drug; Endotoxins; Humans; Leukocytes, Mononuclear; Ofloxacin; Pefloxacin; Tumor Necrosis Factor-alpha | 1990 |
Quinolone therapy of Klebsiella pneumoniae sepsis following irradiation: comparison of pefloxacin, ciprofloxacin, and ofloxacin.
Topics: Animals; Ciprofloxacin; Female; Klebsiella Infections; Klebsiella pneumoniae; Mice; Ofloxacin; Pefloxacin; Radiation Injuries, Experimental | 1990 |
[In vitro activity of 4 fluoroquinolones against Klebsiella pneumoniae. Distribution according to phenotype resistance to aminoglycosides or beta-lactams].
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; In Vitro Techniques; Klebsiella pneumoniae; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype | 1990 |
[Pefloxacin in the treatment of recurrent urinary tract infections].
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Ofloxacin; Pefloxacin; Recurrence; Urinary Tract Infections | 1990 |
The influence of quinolones on the faecal flora.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Feces; Humans; Intestines; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
[Treatment of salmonellosis and shigellosis with the new quinolones].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Ciprofloxacin; Dysentery, Bacillary; Female; Humans; Male; Middle Aged; Ofloxacin; Pefloxacin; Salmonella; Salmonella Infections; Shigella | 1990 |
Comparative postantibacterial activities of pefloxacin, ciprofloxacin, and ofloxacin against intracellular multiplication of Legionella pneumophila serogroup 1.
Topics: Cell Division; Ciprofloxacin; Humans; Intracellular Fluid; Legionella; Macrophages; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Serotyping; Time Factors | 1990 |
[Antibacterial activity of norfloxacin, ofloxacin and ciprofloxacin according to resistance phenotypes to nalidixic acid and pefloxacin].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Aerobic Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype; Staphylococcus aureus | 1990 |
In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin.
Topics: Aeromonas; Anti-Infective Agents; Campylobacter; Corynebacterium; Enterobacteriaceae; Fluoroquinolones; Haemophilus; Neisseria gonorrhoeae; Ofloxacin; Pefloxacin; Quinolones; Staphylococcus aureus | 1989 |
[Activity of 5 fluoroquinolones on hospital Gram-negative bacilli with different sensitivities to pefloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Pseudomonas aeruginosa; Serratia marcescens | 1989 |
Evaluation of pefloxacin, ofloxacin and ciprofloxacin in the treatment of thirty-nine cases of chronic osteomyelitis.
Topics: Administration, Oral; Adult; Bacterial Infections; Ciprofloxacin; Drug Evaluation; Escherichia coli; Female; Humans; Male; Ofloxacin; Osteomyelitis; Pefloxacin; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis | 1989 |
[In vitro susceptibility of Campylobacter jejuni and Campylobacter coli to quinolone antibiotics].
Topics: Anti-Infective Agents; Campylobacter; Campylobacter jejuni; Ciprofloxacin; Feces; Fleroxacin; Humans; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin | 1989 |
Pharmacokinetics of three newer quinolones in pregnant and lactating women.
Topics: Adult; Ciprofloxacin; Female; Humans; Lactation; Maternal-Fetal Exchange; Milk, Human; Ofloxacin; Pefloxacin; Pregnancy; Pregnancy Trimester, Third | 1989 |
Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.
Topics: Bone Marrow Cells; Cell Division; Humans; Ofloxacin; Pefloxacin | 1989 |
Susceptibility of Coxiella burnetii to pefloxacin and ofloxacin in ovo and in persistently infected L929 cells.
Topics: Animals; Cell Line; Cells, Cultured; Chick Embryo; Chickens; Coxiella; Eggs; Mice; Ofloxacin; Pefloxacin; Time Factors | 1989 |
[In vitro determination of the sensitivity of mycobacteria to fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycobacterium; Norfloxacin; Ofloxacin; Pefloxacin | 1989 |
Effect of fluoroquinolones on the in-vitro proliferation of myeloid precursor cells.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cell Division; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Female; Granulocytes; Hematopoietic Stem Cells; Macrophages; Mice; Ofloxacin; Pefloxacin | 1989 |
[In vivo bactericidal effect of ciprofloxacin, ofloxacin and pefloxacin against Staphylococcus aureus].
Topics: Animals; Ciprofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 1989 |
Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Ciprofloxacin; L-Lactate Dehydrogenase; Liver; Male; Ofloxacin; Pefloxacin; Rats; Rats, Inbred Strains | 1989 |
The role of quinolones in staphylococcal infection.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin; Staphylococcal Infections | 1989 |
Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production.
Topics: Humans; Immunoglobulin G; Lymphocytes; Neutrophils; Ofloxacin; Pefloxacin; Superoxides | 1988 |
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors | 1988 |
Clinical use of the quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Osteomyelitis; Oxazines; Pefloxacin; Quinolines; Respiratory Tract Infections; Sexually Transmitted Diseases; Surgical Wound Infection; Urinary Tract Infections | 1987 |
[New oral quinolone compounds in chronic bronchitis].
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; Middle Aged; Naphthyridines; Neisseria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pneumococcal Infections; Pseudomonas Infections; Quinolines; Streptococcus pneumoniae | 1986 |
Quantitative determination of ofloxacin, ciprofloxacin, norfloxacin and pefloxacin in serum by high pressure liquid chromatography.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Spectrophotometry, Ultraviolet | 1986 |
Comparative in vitro activities of ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin against Bacteroides fragilis and Clostridium difficile.
Topics: Anti-Bacterial Agents; Bacteroides fragilis; Ciprofloxacin; Clostridium; Enoxacin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
In-vitro activity of newer quinolones against aerobic bacteria.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Calcium; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Magnesium Sulfate; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas; Quinolines; Sulfates; Zinc; Zinc Sulfate | 1986 |
Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile.
Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Clostridium; Enoxacin; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
Photoonycholysis induced by the fluoroquinolones pefloxacine and ofloxacine. Report on 2 cases.
Topics: Aged; Aged, 80 and over; Drug Eruptions; Humans; Male; Mycosis Fungoides; Nail Diseases; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Photosensitivity Disorders; PUVA Therapy | 1986 |
Drug-induced photo-onycholysis. Three subtypes identified in a study of 15 cases.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Doxycycline; Drug Eruptions; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Photosensitivity Disorders; PUVA Therapy; Tetracycline; Trioxsalen; Ultraviolet Rays | 1987 |
[Biotransformation of selected gyrase inhibitors].
Topics: Anti-Infective Agents; Biotransformation; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Clinical uses of nalidixic acid analogues: the fluoroquinolones.
Topics: Administration, Oral; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Male; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Topoisomerase II Inhibitors | 1986 |
[Rickettsiaceae infections and fluoroquinolones].
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Boutonneuse Fever; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pregnancy; Q Fever; Rifampin | 1988 |
Activity of ofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Anti-Bacterial Agents; Dapsone; Female; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Prothionamide | 1988 |
Plasmid "curing" by some recently synthetized 4-quinolone compounds.
Topics: Escherichia coli; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Pefloxacin; Plasmids | 1988 |
Inhibition of plasmid conjugation by some recently synthetized 4-quinolone compounds.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; R Factors | 1988 |
[Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Staphylococcus aureus | 1986 |
In vitro activity of RO 23-6240 (AM-833): a new fluoroquinolone.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in-vitro activity of five fluoroquinolones against mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Mycobacterium; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; Naphthyridines; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria].
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1987 |
In vitro activity of five new quinolones against cultivable mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of four fluoroquinolones against eighty-six isolates of mycobacteria.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Enhancement of interleukin 2 production by quinolone-treated human mononuclear leukocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; In Vitro Techniques; Interleukin-2; Kinetics; Leukocytes, Mononuclear; Lymphocyte Activation; Mitomycin; Mitomycins; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Receptors, Immunologic; Receptors, Interleukin-2 | 1988 |
[In vitro antibacterial activity of piperacillin/quinolone combinations].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens | 1988 |
[Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus].
Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Penicillin G; Vancomycin | 1988 |
[Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis].
Topics: Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Vancomycin | 1988 |
[Sensitivity of 7 mycobacterial species to new quinolones].
Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Drug Synergism; Erythromycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sulfamethoxazole; Thienamycins; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Mycoplasmataceae; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Quinolones; Ureaplasma | 1988 |
[In vitro activity of 3 fluoroquinolones on Branhamella catarrhalis].
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Pefloxacin; Respiratory Tract Infections | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
[Effect ofloxacin on Haemophilus influenza, Streptococcus pneumoniae and Neisseria meningitidis. Comparison with similar molecules].
Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Haemophilus influenzae; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria meningitidis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Streptococcus pneumoniae | 1985 |
[Comparison of the in vitro activity of 6 quinolones on Pseudomonas sp].
Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Pseudomonas; Pseudomonas aeruginosa; Quinolines | 1985 |
[Comparative in vitro study of the activity of 5 quinolones against Acinetobacter calcoaceticus].
Topics: Acinetobacter; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1985 |
[Sensitivity of obligate anaerobes to ofloxacin, pefloxacin, enoxacin and norfloxacin].
Topics: Bacteria, Anaerobic; Bacteroides; Clostridium; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1985 |
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Pipemidic Acid; Proteus; Providencia; Urinary Tract Infections | 1988 |
[The in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections].
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Ofloxacin; Pefloxacin; Pseudomonas; Urinary Tract Infections | 1988 |
In vitro activities of five new quinolones against 88 genital and neonatal Haemophilus isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Female; Genital Diseases, Female; Genital Diseases, Male; Haemophilus; Haemophilus Infections; Haemophilus influenzae; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1988 |
[In vitro antibacterial activity of 2 new quinolones: A 56619 (difloxacin) and A 56620. Comparison with pefloxacin, ofloxacin and ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
[Modulation by quinolones of the in vitro proliferative response of splenic cells of the mouse and IL 1 production].
Topics: Animals; Anti-Infective Agents; Cell Division; Cells, Cultured; Ciprofloxacin; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred DBA; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Spleen | 1987 |
[Antibiotics and chemotaxis in agarose. The role of incubation conditions and application to several fluoroquinolones].
Topics: Anti-Infective Agents; Cell Movement; Chemotaxis, Leukocyte; Doxycycline; Humans; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sepharose | 1987 |
Fluoroquinolone derivatives: effects on neutrophil functional tests.
Topics: Anti-Infective Agents; Candida albicans; Chemotaxis, Leukocyte; Ciprofloxacin; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis; Staphylococcus aureus | 1987 |
Quinolone antimicrobial agents in acute exacerbations of chronic bronchitis.
Topics: Anti-Infective Agents; Bacterial Infections; Bronchitis; Ciprofloxacin; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
[Gyrase inhibitors: unwanted central nervous system effects].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brain Chemistry; Brain Diseases; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Solubility | 1987 |
The comparative pharmacokinetics of five quinolones.
Topics: Administration, Oral; Adult; Ciprofloxacin; Enoxacin; Half-Life; Humans; Infusions, Intravenous; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
Effects of quinolones on granulocyte function in vitro.
Topics: Anti-Infective Agents; Cell Survival; Ciprofloxacin; Hexosephosphates; Humans; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Phagocytosis | 1986 |
In-vitro selection of bacteria resistant to the 4-quinolone agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Staphylococcus; Streptococcus | 1987 |
Comparative in vitro activities of pefloxacin, ofloxacin, enoxacin and ciprofloxacin against 256 clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of ciprofloxacin, ofloxacin and pefloxacin against resistant clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of amifloxacin and five other fluoroquinolone antimicrobial agents and preliminary criteria for the disk susceptibility test.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
[Therapeutic contribution of the new quinolones].
Topics: Anti-Infective Agents; Bacterial Infections; Biotransformation; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Therapy, Combination; Humans; Kinetics; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Activity of ofloxacin and pefloxacin against Mycobacterium leprae in mice.
Topics: Animals; Drug Evaluation, Preclinical; Leprosy; Mice; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
The adverse effects of fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
New synthetic quinolone antibacterial agents and serum concentration of theophylline.
Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline | 1987 |
Polymorphonuclear leucocyte chemotaxis little affected by three quinolones in vitro.
Topics: Anti-Infective Agents; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
Comparative pharmacokinetics of new quinolones.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
[Fluoroquinolones].
Topics: Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
Comparative effects of quinolones on human mononuclear leucocyte functions.
Topics: Cell Survival; Ciprofloxacin; Humans; Indomethacin; Interleukin-1; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Monocytes; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Clinical efficacy of the new quinolones in lower respiratory infections.
Topics: Aged; Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pefloxacin; Respiratory Tract Infections; Sputum | 1987 |
Ofloxacin: antibacterial activity, induction of resistance and killing curves.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid | 1985 |
Antibacterial activity of ofloxacin and other 4-quinolone derivatives: in-vitro and in-vivo comparison.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Blood Proteins; Drug Resistance, Microbial; Male; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding | 1985 |
[Comparative bacteriologic activity of norfloxacin, ofloxacin and pefloxacin against 320 Gram-negative bacilli resistant and non-resistant to nalidixic acid and cephalosporins].
Topics: Acinetobacter; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas aeruginosa | 1985 |
In vitro activity of ciprofloxacin against clinical isolates of Chlamydia trachomatis.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1984 |
Pefloxacine mesilate- and ofloxacin-loaded polyethylcyanoacrylate nanoparticles: characterization of the colloidal drug carrier formulation.
Topics: Biological Availability; Mathematics; Molecular Structure; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Time Factors | 1995 |
In vitro activity of eight antibiotics against Salmonella and Shigella species.
Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fleroxacin; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Salmonella; Shigella; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
Effects of fluoroquinolones on cultured articular chondrocytes flow cytometric analysis of free radical production.
Topics: Animals; Anti-Infective Agents; Cartilage; Cell Survival; Cells, Cultured; Ciprofloxacin; Flow Cytometry; Free Radicals; Macrophages, Alveolar; Nalidixic Acid; Ofloxacin; Pefloxacin; Rabbits | 1994 |
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?
Topics: Biological Transport; Carbon Radioisotopes; Cells, Cultured; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Humans; Intestinal Mucosa; Norfloxacin; Ofloxacin; Pefloxacin; Quinolizines | 1994 |
Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Cartilage Diseases; Cartilage, Articular; Flow Cytometry; Fluorescent Dyes; Fluorometry; Microscopy; Mitochondria; Ofloxacin; Pefloxacin; Rabbits; Respiratory Burst; Sensitivity and Specificity | 1994 |
Mathematical model for comparison of time-killing curves.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cell Cycle; Cephalothin; Escherichia coli; Kinetics; Mathematical Computing; Microbial Sensitivity Tests; Models, Biological; Nalidixic Acid; Ofloxacin; Pefloxacin; Time Factors | 1993 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
Determination of MICs for staphylococci using the API ATB quinolone and API ATB macrolide systems.
Topics: Ciprofloxacin; Clindamycin; Dose-Response Relationship, Drug; Erythromycin; Humans; In Vitro Techniques; Lincomycin; Microbiological Techniques; Nalidixic Acid; Ofloxacin; Pefloxacin; Staphylococcus; Virginiamycin | 1993 |
Lack of effect of ketoprofen on the pharmacokinetics of pefloxacin and ofloxacin.
Topics: Adult; Humans; Ketoprofen; Male; Ofloxacin; Pefloxacin | 1993 |
Comparative pharmacokinetics of ciprofloxacin, ofloxacin and pefloxacin in human aqueous humour.
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Ciprofloxacin; Female; Humans; Male; Middle Aged; Ofloxacin; Pefloxacin; Premedication | 1993 |
[Excretion of fluoroquinolones into saliva].
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Mice; Ofloxacin; Pefloxacin; Rabbits; Saliva | 1995 |
Stereoselectivity of ofloxacin intestinal transport in the rat.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Intestinal Absorption; Male; Ofloxacin; Pefloxacin; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1995 |
Modulation of biofilms of Pseudomonas aeruginosa by quinolones.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Catheterization; Ciprofloxacin; Glycoproteins; Norfloxacin; Ofloxacin; Pefloxacin; Polysaccharides; Pseudomonas aeruginosa | 1995 |
Carrier-mediated system for pefloxacin uptake in human monocytes.
Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Biological Transport; Calcium; Humans; Hydrogen-Ion Concentration; Monocytes; Ofloxacin; Pefloxacin; Verapamil | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
A comparative study of anxiogenic effects of fluoroquinolones in rats.
Topics: Animals; Anti-Infective Agents; Anxiety; Ciprofloxacin; Female; Injections, Intraperitoneal; Male; Ofloxacin; Pefloxacin; Rats | 1998 |
Fluoroquinolone antibiotics block neuromuscular transmission.
Topics: Animals; Anti-Infective Agents; Electrophysiology; Motor Endplate; Neuromuscular Junction; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar; Synaptic Transmission | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin.
Topics: Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Coxiella burnetii; Doxycycline; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin | 1998 |
The system of objective judgement analysis method: less objectivity than pretended?
Topics: Ciprofloxacin; Dosage Forms; Drug Administration Routes; Drug Utilization; Ofloxacin; Pefloxacin; Statistics as Topic | 1995 |
Neuropsychiatric complications following quinolone overdose in renal failure.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Confusion; Drug Overdose; Female; Humans; Kidney Failure, Chronic; Ofloxacin; Pefloxacin; Urinary Tract Infections | 1999 |
In-vitro activity of levofloxacin, a new fluoroquinolone: evaluation against Haemophilus influenzae and Moraxella catarrhalis.
Topics: Anti-Infective Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Pefloxacin | 1999 |
Adverse testicular effects of some quinolone members in rats.
Topics: Acid Phosphatase; Animals; Anti-Infective Agents; Ciprofloxacin; Fertility; L-Lactate Dehydrogenase; Male; Ofloxacin; Organ Size; Pefloxacin; Prostate; Rats; Sperm Count; Sperm Motility; Testicular Diseases; Testis | 2000 |
[Effect of ofloxacin, pefloxacin, and tobramycin on the hydrophobicity of Klebsiella pneumoniae].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dose-Response Relationship, Drug; Klebsiella pneumoniae; Ofloxacin; Pefloxacin; Tobramycin | 1999 |
[Comparative efficacy and safety of ciprofloxacin, ofloxacin, and pefloxacin in treatment of respiratory infections in children with cystic fibrosis].
Topics: Adolescent; Anti-Infective Agents; Arthritis; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Microbial; Female; Humans; Infant; Knee Joint; Male; Ofloxacin; Pefloxacin; Respiratory Tract Infections | 2001 |
Eradicative effect of cotrimoxazole and quinolones on non-typhoid salmonellae.
Topics: Anti-Bacterial Agents; Female; Humans; Male; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Retrospective Studies; Salmonella; Salmonella Food Poisoning; Salmonella Infections; Trimethoprim, Sulfamethoxazole Drug Combination | 2001 |
[Tenotoxic potential of fluoroquinolones in the choice of surgical antibiotic prophylaxis in ophthalmology].
Topics: Achilles Tendon; Aged; Animals; Antibiotic Prophylaxis; Cells, Cultured; Ciprofloxacin; Data Interpretation, Statistical; Fluoroquinolones; Free Radicals; Humans; Levofloxacin; Middle Aged; Ofloxacin; Ophthalmologic Surgical Procedures; Pefloxacin; Rabbits; Rupture; Tendons; Time Factors | 2002 |
The effect of nitric oxide combined with fluoroquinolones against Salmonella enterica serovar Typhimurium in vitro.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Salmonella typhimurium; Transcription Factors; Triazenes | 2003 |
A comparison of effects of fluoroquinolones on fracture healing (an experimental study in rats).
Topics: Animals; Ciprofloxacin; Femoral Fractures; Fluoroquinolones; Fracture Healing; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar | 2005 |
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Models, Chemical; Models, Statistical; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Quinolones; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Temperature; Time Factors | 2006 |
[Properties of the Burkholderia pseudomallei insertional mutants deficient in membrane proteins production].
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Burkholderia pseudomallei; Ceftazidime; Chromosomes, Bacterial; DNA Transposable Elements; Drug Resistance, Bacterial; Guinea Pigs; Melioidosis; Membrane Proteins; Mice; Mutation; Ofloxacin; Pefloxacin; Virulence | 2005 |
Age-dependent effects on redox status, oxidative stress, mitochondrial activity and toxicity induced by fluoroquinolones on primary cultures of rabbit tendon cells.
Topics: Achilles Tendon; Age Factors; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fluoroquinolones; Glutathione; Mitochondria; Nalidixic Acid; Ofloxacin; Oxidation-Reduction; Oxidative Stress; Pefloxacin; Rabbits; Reactive Oxygen Species | 2006 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
[Chemotherapy activity and pharmacokinetics of the fluoroquinolones generics Ofloxacin-PhPO and Pefloxacin-genova].
Topics: Animals; Anti-Bacterial Agents; Drugs, Generic; Male; Mice; Ofloxacin; Pefloxacin; Rabbits | 2007 |
Effect of levofloxacin and pefloxacin on humoral immune response elicited by bovine serum albumin docked in gelatin microparticles and nanoparticles.
Topics: Animals; Anti-Bacterial Agents; Drug Compounding; Drug Stability; Electrochemistry; Enzyme-Linked Immunosorbent Assay; Excipients; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gelatin; Glutaral; Immunity, Humoral; Immunoglobulin E; Immunologic Factors; Indicators and Reagents; Levofloxacin; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Ofloxacin; Particle Size; Pefloxacin; Rats; Rats, Wistar; Serum Albumin, Bovine | 2010 |
Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: comparison of biomechanical and histopathological effects on Achilles tendon in rats.
Topics: Achilles Tendon; Administration, Oral; Animals; Anti-Bacterial Agents; Ciprofloxacin; Elastic Modulus; Elasticity; Fluoroquinolones; Male; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar; Tensile Strength | 2011 |
Application of non-linear angle synchronous spectrofluorimetry to the determination of complex mixtures of drugs in urine: a comparative study.
Topics: Anti-Infective Agents; Calibration; Enoxacin; Humans; Least-Squares Analysis; Limit of Detection; Ofloxacin; Pefloxacin; Spectrometry, Fluorescence | 2012 |
Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica.
Topics: Anti-Bacterial Agents; Bacteremia; Base Sequence; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Nalidixic Acid; Ofloxacin; Pefloxacin; Salmonella enterica; Salmonella Infections; Sequence Analysis, DNA | 2015 |
Antibiotics and antimycotics in waste water treatment plants: Concentrations, removal efficiency, spatial and temporal variations, prediction, and ecological risk assessment.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Clotrimazole; Environmental Monitoring; Moxifloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Risk Assessment; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2022 |
Fluorescent strip sensor for rapid and ultrasensitive determination of fluoroquinolones in fish and milk.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Humans; Milk; Norfloxacin; Ofloxacin; Pefloxacin | 2023 |
Synthesis of a dual-functional terbium doped copper oxide nanoflowers for high-efficiently electrochemical sensing of ofloxacin, pefloxacin and gatifloxacin.
Topics: Copper; Electrochemical Techniques; Electrodes; Gatifloxacin; Ofloxacin; Oxides; Pefloxacin; Terbium | 2023 |
Evaluation of post-antibiotic effects of antipseudomonal antibiotics using an automated system.
Topics: 4-Quinolones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Automation; Ceftazidime; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Netilmicin; Ofloxacin; Pefloxacin; Pseudomonas; Pseudomonas aeruginosa; Pseudomonas Infections | 2000 |
Effect of fluorinated quinolones on heat-labile toxin production by Escherichia coli.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Ciprofloxacin; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin | 1989 |