ofloxacin and novobiocin

ofloxacin has been researched along with novobiocin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's5 (25.00)18.2507
2000's6 (30.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubry, A; Cambau, E; Jarlier, V; Matrat, S1
Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z1
Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW1
Hanaki, H; Maseda, H; Nakae, T; Sugimura, M1
Banères-Roquet, F; Gualtieri, M; Leonetti, JP; Pugnière, M; Villain-Guillot, P1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Babu, KS; Jeankumar, VU; Reddy, KI; Renuka, J; Shravan, M; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P1
Babu, KS; Chuppala, A; Jeankumar, VU; Reddy, KI; Renuka, J; Sree, KS; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P1
Renuka, J; Samala, G; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P1
Janupally, R; Jeankumar, VU; Reshma, RS; Saxena, S; Sriram, D; Vats, R; Yogeeswari, P1
Chaudhari, K; Jain, P; Patel, HM; Surana, S1
Howard, BM; Lewin, CS; Smith, JT1
Gocke, E1
Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC1
Grosse, F; Hussy, P; Maass, G; Schomburg, U; Tümmler, B1
Fraimow, HS; French, P; Venuti, E1
Howard, BM; Pinney, RJ; Smith, JT1
Bernard, FX; Bisch, D; Blanche, F; Cameron, B; Crouzet, J; Ferrero, L; Goniot, A; Lecoq, C; Manse, B; Maton, L; Ratet, N1
Bedoui, A; Chekir-Ghedira, L; Cheraif, I; Dhaouifi, Z; Ghedira, K; Kalboussi, Z; Lahmar, A; Mokdad-Bzeouich, I1

Reviews

1 review(s) available for ofloxacin and novobiocin

ArticleYear
Mycobacterium Tuberculosis (MTB) GyrB inhibitors: An attractive approach for developing novel drugs against TB.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Antitubercular Agents; Clinical Trials as Topic; DNA Gyrase; Drug Discovery; Humans; Mycobacterium tuberculosis; Topoisomerase II Inhibitors

2016

Other Studies

19 other study(ies) available for ofloxacin and novobiocin

ArticleYear
Are all the DNA gyrase mutations found in Mycobacterium leprae clinical strains involved in resistance to fluoroquinolones?
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Anti-Infective Agents; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae

2008
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin

2008
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9

    Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin

2008
Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Outer Membrane Proteins; Down-Regulation; Humans; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2008
Use of a surface plasmon resonance method to investigate antibiotic and plasma protein interactions.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Anti-Bacterial Agents; Blood Proteins; Protein Binding; Surface Plasmon Resonance

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17

    Topics: Animals; Antitubercular Agents; Benzofurans; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.
    Bioorganic & medicinal chemistry, 2014, Dec-01, Volume: 22, Issue:23

    Topics: Animals; Antitubercular Agents; Benzofurans; Benzothiazoles; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.
    Bioorganic & medicinal chemistry, 2015, Apr-01, Volume: 23, Issue:7

    Topics: Antitubercular Agents; DNA Gyrase; Drug Discovery; Humans; Mycobacterium smegmatis; Mycobacterium tuberculosis

2015
Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Adenosine Triphosphatases; Antitubercular Agents; DNA Gyrase; Drug Discovery; Engineering; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Protein Conformation

2016
4-Quinolone interactions with gyrase subunit B inhibitors.
    Journal of medical microbiology, 1991, Volume: 35, Issue:6

    Topics: Aminocoumarins; Anti-Infective Agents; Coumarins; Dose-Response Relationship, Drug; Drug Interactions; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Staphylococcus aureus; Topoisomerase II Inhibitors

1991
Mechanism of quinolone mutagenicity in bacteria.
    Mutation research, 1991, Volume: 248, Issue:1

    Topics: Anti-Infective Agents; Blotting, Southern; Ciprofloxacin; DNA Topoisomerases, Type II; Enrofloxacin; Escherichia coli; Fleroxacin; Fluoroquinolones; Genes, Bacterial; Mutation; Novobiocin; Ofloxacin; Oxolinic Acid; Quinolones; Salmonella

1991
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8

    Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors

1988
Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:6

    Topics: Cell Division; Cell Line; Ciprofloxacin; DNA Polymerase II; DNA Topoisomerases, Type I; DNA, Bacterial; Electrophoresis, Agar Gel; Humans; Lymphocytes; Novobiocin; Ofloxacin; Oxazines; Quinolines; Spheroplasts; Thymus Gland

1986
In vitro activity of novobiocin against multiresistant strains of Enterococcus faecium.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:12

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enterococcus faecium; Novobiocin; Ofloxacin

1993
Antagonism between bactericidal activities of 4-quinolones and coumarins gives insight into 4-quinolone killing mechanisms.
    Microbios, 1994, Volume: 77, Issue:311

    Topics: Aminocoumarins; Anti-Infective Agents; Ciprofloxacin; Coumarins; DNA Topoisomerases, Type II; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Rifampin

1994
Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Fluoroquinolones; Novobiocin; Ofloxacin; Quinolones; Staphylococcus aureus; Substrate Specificity; Topoisomerase II Inhibitors

1996
Reversal of resistance in bacteria underlies synergistic effect of essential oils with conventional antibiotics.
    Microbial pathogenesis, 2017, Volume: 106

    Topics: Acinetobacter baumannii; Amoxicillin; Animals; Anti-Infective Agents; Bacteria; beta-Lactamases; Bicyclic Monoterpenes; Cell Line; Cell Proliferation; Cell Survival; Cyclohexenes; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Escherichia coli; Gas Chromatography-Mass Spectrometry; Humans; Keratinocytes; Limonene; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Monoterpenes; Novobiocin; Ofloxacin; Oils, Volatile; Oxacillin; Piperacillin; Plant Extracts; Plant Oils; Sesquiterpenes, Eudesmane; Spleen; Terpenes; Tetracycline; Time Factors

2017