ofloxacin has been researched along with norfloxacin in 445 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 155 (34.83) | 18.7374 |
| 1990's | 109 (24.49) | 18.2507 |
| 2000's | 86 (19.33) | 29.6817 |
| 2010's | 69 (15.51) | 24.3611 |
| 2020's | 26 (5.84) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ | 1 |
| Culbertson, TP; Gambino, L; Sanchez, JP; Sesnie, JA | 1 |
| Chu, DT; Mitscher, LA; Pernet, AG; Sharma, PN; Shen, LL | 1 |
| Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M | 1 |
| Domagala, JM; Heifetz, CL; Mich, TF; Nichols, JB | 1 |
| Cecchetti, V; Fravolini, A; Fringuelli, R; Mascellani, G; Pagella, P; Palmioli, M; Segre, G; Terni, P | 1 |
| Araki, K; Hirayama, F; Ikeda, Y; Iwao, E; Kuroda, T; Moriguchi, A; Uemori, S; Yakushiji, T; Yokoyama, Y | 1 |
| Kawakami, K; Okuno, T; Sakamoto, F; Tsukamoto, G; Uno, T | 1 |
| Apiwattanakul, N; Endou, H; Jariyawat, S; Kanai, Y; Sekine, T; Sophasan, S; Takeda, M | 1 |
| Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Arpin, C; Ba, BB; Caignard, DH; Forfar-Bares, I; Grellet, J; Guillon, J; Jarry, C; Moreau, S; Quentin, C; Vidaillac, C | 1 |
| Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N | 1 |
| Cattoir, V; Mazel, D; Nordmann, P; Poirel, L; Soussy, CJ | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 2 |
| Amblard, M; Bastide, L; Gualtieri, M; Leonetti, JP; Martinez, J; Pugniere, M; Roquet, F; Villain-Guillot, P | 1 |
| Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A | 1 |
| Chen, T; Khalil, H; Riffon, R; Wang, R; Wang, Z | 1 |
| Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L | 1 |
| Cattoir, V; Espinal, P; Nordmann, P; Poirel, L; Silva-Sanchez, J | 1 |
| Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW | 1 |
| Aarestrup, FM; Cavaco, LM; Hasman, H; Xia, S | 1 |
| Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE | 1 |
| Dionisi, AM; Lucarelli, C; Luzzi, I; Owczarek, S; Villa, L | 1 |
| Chhasatia, MR; Gandhi, DS; Patel, MN | 1 |
| Caddick, JM; Gunell, M; Hakanen, AJ; Huovinen, P; Jalava, J; Kotilainen, P; Lilly, AJ; Piddock, LJ; Siitonen, A; Webber, MA | 1 |
| Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A | 1 |
| Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A | 1 |
| Blango, MG; Mulvey, MA | 1 |
| Avdeef, A; Tam, KY | 1 |
| Ahn, JH; Bae, IK; Lee, JE; Lee, JJ; Lee, SH; Park, I; Park, KS; Sun, HI; Woo, GJ | 1 |
| Mima, T; Schweizer, HP | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Kalinin, AA; Kulik, NV; Mamedov, VA; Voloshina, AD; Zobov, VV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Chen, L; Fan, L; He, ZQ; Jiang, L; Lei, HS; Liu, CP; Liu, J; Peng, XM; Xu, XR; Yang, DC; Zhou, CH; Zhou, FW; Zou, YY | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E | 1 |
| Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW | 1 |
| Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Fatima, N; Gowravaram, S; Kadari, S; Putta, CS; Reddy, BVS; Yadav, JS | 1 |
| Campillo, NE; Cañada, FJ; Canales, A; Carvalho, I; Chierrito, TPC; Martinez, A; Martínez-Gonzalez, L; Pedersoli-Mantoani, S; Perez, C; Pérez, DI; Roca, C; Sebastian-Pérez, V | 1 |
| Zhang, B | 1 |
| Chen, T; Li, Z; Lyu, Y; Shan, A; Shang, L; Yang, Y; Zhu, J | 1 |
| Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Blaskovich, MAT; Pham, TDM; Ziora, ZM | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Rahal, K | 1 |
| Cobbs, CG; Smith, KR | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Arai, S; Gohara, Y; Kawashima, T; Kuwano, K; Matsu-Ura, I | 1 |
| Jones, RN | 1 |
| Kiyota, H; Mitani, H | 1 |
| Erwin, ME; Jones, RN | 1 |
| Foleno, B; Fu, KP | 1 |
| Aoyama, H; Fukuda, H; Hirai, K; Hosaka, M; Tomizawa, H; Yasue, T | 1 |
| Mitsuhashi, S; Wakebe, H | 1 |
| Hayashibara, M; Ichikawa, N; Iwamoto, K; Katagiri, Y; Naora, K | 1 |
| Hoshino, K; Saiki, A; Sawai, T; Yamaguchi, A | 1 |
| Kudo, M; Ohkubo, T; Sugawara, K | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Batmanov, VP | 1 |
| Räisäinen, S; Schildt, R; Syrjälä, H | 1 |
| Baer, JC; Bauer, SA; Glaros, DS; Nirankari, VS | 1 |
| McQueen, CA; Queener, SM; Schlüter, G; Way, BM; Williams, GM | 1 |
| Børsum, T; Dannevig, L; Melby, K; Størvold, G | 1 |
| Esteve, M; Gargallo-Viola, D; Guinea, J; Llovera, S; Roca, X | 1 |
| Deguchi, K; Fukayama, S; Ishihara, R; Koguchi, M; Nakane, Y; Oda, S; Sato, K; Suzuki, Y; Tanaka, S; Yokota, N | 1 |
| Furusawa, M; Iino, T; Marumoto, Y; Nozaki-Renard, J; Ohta, G; Sato, Y | 1 |
| al-Shammary, FJ; Bishop, SJ; Shibl, AM; Shoeb, HA; Tawfik, AF | 1 |
| Boeckk, M; Borner, K; Deppermann, N; Höffken, G; Koeppe, P; Lode, H | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Gemeinhardt, A; Janssen, U; Klotz, U; Unseld, E; Ziegler, G | 1 |
| Barnett, G; Carbó, M; de la Torre, R; Segura, J | 1 |
| Mulert, R; Shah, PM | 1 |
| Guenounou, M; Miguères, ML; Ronco, E | 1 |
| Minami, S; Nishida, N; Noumi, T; Watanabe, Y; Yasuda, T | 1 |
| Midtvedt, T | 1 |
| Alestig, K | 1 |
| Nakanishi, S; Okuno, H | 1 |
| Matsumoto, F; Morita, M; Takahashi, T | 1 |
| Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| Faegri, A; Melby, K | 1 |
| Aubert, G; Denis, M; Dorche, G; Loboguerrero, M; Lucht, F; Puech, C | 1 |
| Kotera, Y; Mitsuhashi, S | 1 |
| Dopp, C; Naumann, P | 1 |
| Nishino, T; Obana, Y | 1 |
| Hooper, DC; Wolfson, JS | 2 |
| Goto, M; Kawakatsu, K; Sano, M; Takeyama, M; Yamamoto, I; Yamashina, H | 1 |
| Dailloux, M; Henry, C; Petitpain, N; Weber, M | 1 |
| Kashimoto, S; Kojima, T; Kouno, K; Kurobe, N; Minami, A; Nakamura, S; Nakata, K; Ohue, T; Sakaguchi, Y; Yoshida, H | 1 |
| Hoffner, SE; Källenius, G; Kratz, M; Olsson-Liljequist, B; Svenson, SB | 1 |
| Shah, PM | 2 |
| Harder, S; Papenburg, A; Staib, AH; Stille, W | 1 |
| Dalhoff, A; Döring, G | 1 |
| Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC | 1 |
| Beer, C; Harder, S; Papenburg, A; Shah, PM; Staib, AH; Stille, W | 1 |
| Neu, HC | 3 |
| Appleman, ME; Gaines, JK; Hadfield, TL; Winn, RE | 1 |
| Santos Ferreira, M; Vital, J | 1 |
| Benonisen, E; Dibb, WL; Digranes, A | 1 |
| Bergkvist, PI; Forsgren, A | 1 |
| Baur, C; Davies, BI; Maesen, FP; Teengs, JP | 2 |
| Brouwers, JR; Groeneveld, AJ | 1 |
| Edlund, C; Nord, CE | 2 |
| Bailey, J; Heppleston, C; Richmond, SJ | 1 |
| Auckenthaler, R; Michéa-Hamzehpour, M; Pechère, JC | 1 |
| Smith, SM | 1 |
| Avesani, V; Delmee, M | 1 |
| Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL | 2 |
| Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH | 1 |
| Zeiler, HJ | 1 |
| Grohe, K; Metzger, KG; Schacht, P; Zeiler, HJ | 1 |
| Baltch, AL; Bassey, CM; Smith, RP | 1 |
| Barry, AL; Jones, RN; Thornsberry, C | 1 |
| Aoyama, H; Hirai, K; Hosaka, M; Irikura, T; Niwata, Y; Oomori, Y; Suzue, S | 1 |
| Bremm, KD; Dahlhoff, A; Knöller, J; König, W; Schönfeld, W; Weber, B | 1 |
| Baran, R; Brun, P | 1 |
| Baran, R; Juhlin, L | 1 |
| Grimm, H | 2 |
| Borner, K; Lode, H | 1 |
| Høiby, N | 1 |
| Hayakawa, I; Imamura, M; Osada, Y; Shibamura, S | 1 |
| Just, G; Shah, PM; Stille, W; Weigand, G | 1 |
| Bertrand, A; Janbon, F; Jonquet, O; Reynes, J | 1 |
| Beoletto, C; Grosset, JH; Guelpa-Lauras, CC; Perani, EG | 1 |
| Kawaguchi, K; Yamaguchi, K | 1 |
| Cohen, SP; Hooper, DC; Levy, SB; McMurry, LM; Souza, KS; Wolfson, JS | 1 |
| Osada, Y; Une, T | 1 |
| Cellini, L; Oliva, B; Renzini, G; Scazzocchio, F; Schippa, S; Selan, L | 1 |
| Bauernfeind, A; Gablac, R; Heinrich, B; Petermüller, C | 1 |
| Baldinelli, L; De Santis, S; De Simone, C; Ferrazzi, M; Pugnaloni, L; Sorice, F | 1 |
| Ballard, RC; Fehler, G; Koornhof, HJ; Liebowitz, LD; Saunders, J | 1 |
| Fass, RJ; Helsel, VL | 1 |
| Davies, S; Sparham, PD; Spencer, RC | 1 |
| Berlin, OG; Bruckner, DA; Young, LS | 1 |
| Kudoh, Y; Matsushita, S; Ohashi, M; Yamada, S | 1 |
| Saito, H; Sato, K; Tomioka, H; Watanabe, T | 1 |
| Habiyaremye, I; Vandepitte, J; Verbist, L | 1 |
| Braveny, I; Machka, K | 1 |
| Kubesch, P; Tümmler, B; Wehsling, M | 1 |
| Verbist, L | 1 |
| Pattyn, SR; Van Caekenberghe, DL; Verhoeven, JR | 1 |
| Bébéar, C; Fourche, J; Mormède, M; Texier-Maugein, J | 1 |
| Fay, M; Gougerot-Pocidalo, MA; Roche, Y | 1 |
| Kohl, KH; Spohr, M; Traub, WH | 1 |
| Duval, J; Leclercq, R; Soussy, CJ | 1 |
| Armynot du Chatelet, AM; Attisso, MA; Maillols, M; Simeon de Buochberg, M; Zuccarelli, M | 1 |
| Attisso, MA; Dusart, G; Maillols, H; Simeon de Buochberg, M; Zuccarelli, M | 1 |
| Cancet, B; Clave, D; Didier, J; Henry-Ferry, S; Marty, N | 1 |
| de Micco, P; Gevaudan, MJ; Gulian, C; Lagier, P; Mallet, MN; Terriou, P | 1 |
| Bebear, C; de Barbeyrac, B; Quentin, C; Renaudin, H | 1 |
| Hashimoto, Y; Itoh, N; Kawakami, S; Konno, M; Ohonari, S; Ubukata, K | 1 |
| Kresken, M; Wiedemann, B | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Concia, E; Cruciani, M; Monzillo, V; Navarra, A; Tinelli, C | 1 |
| Nagayama, A; Nakao, T; Taen, H | 1 |
| el-Baz, F; Osman, LM; Sabbour, MS | 1 |
| Baars, B; Cullmann, W; Opferkuch, W; Stieglitz, M | 1 |
| Forsgren, A | 1 |
| Butzler, JP; Coignau, H; De Mol, P; Ghysels, G; Goossens, H; Grados, O; Innocent, H; Levy, J | 1 |
| Bailey, J; Heppleston, C; Richmond, S | 1 |
| Dabernat, H; Delmas, C; Lareng, MB | 1 |
| Daguet, GL; Delisle-Mizon, F; Lesage, D; Vergez, P | 1 |
| Bergogne-Berezin, E; Joly-Guillou, ML | 1 |
| Bryskier, A; Devos, J; Dubreuil, L; Romond, C | 1 |
| Palù, G; Palumbo, M; Peracchi, M; Valisena, S | 1 |
| Gulden, H; Kern, W; Kurrle, E; Vanek, E | 1 |
| Kurata, T; Okazaki, O; Tachizawa, H | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Goto, M; Kawakatsu, K; Ohkita, C; Sano, M; Takeyama, M; Yamamoto, I; Yamashina, H | 1 |
| Asakawa, M; Yasumoto, R | 1 |
| Hirschl, AM; Rotter, M | 1 |
| Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L | 1 |
| Cattier, B; Gavignet, M; Goudeau, A; Koubaa, N; Quentin, R | 1 |
| Beermann, D; Förster, D; Schacht, P; Wingender, W; Zeiler, HJ | 1 |
| Bergan, T; Dalhoff, A; Rohwedder, R | 1 |
| Ida, S; Ohno, I | 1 |
| Deforges, L; Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| Fisch, A; Forestier, F; Lafaix, C; Meulemans, A; Montay, G; Salvanet, A | 1 |
| Guenounou, M; Kodari, E; Momrikof, V; Ronco, E; Vacheron, F | 1 |
| Walker, RC; Wright, AJ | 1 |
| Descotes, J; Lombard, JY | 1 |
| Bersani, C; Bertoletti, R; Fietta, A; Gialdroni Grassi, G; Santagada, T | 1 |
| Fujimoto, T; Katami, K; Osada, Y; Sato, M; Tachizawa, H; Tsumura, M; Une, T | 1 |
| Andrews, JM; Griggs, D; Lister, D; McNulty, CA; Wise, R | 2 |
| Mizuno, S; Toyama, H; Tsukamura, M | 1 |
| Rietbrock, N; Staib, AH | 1 |
| Boogaerts, MA; Malbrain, S; Scheers, W; Verwilghen, RL | 1 |
| Caccamo, F; Nicoletti, G; Nicolosi, VM; Speciale, A; Stefani, S | 1 |
| Dabbs, DJ; Limb, DI; Spencer, RC | 1 |
| Ayers, LW; Barry, AL; Fuchs, PC; Gavan, TL; Gerlach, EH; Jones, RN; Thornsberry, C | 1 |
| Arpi, M; Bentzon, MW; Gahrn-Hansen, B; Søgaard, P | 1 |
| Mazzei, T; Nicoletti, P; Periti, P | 1 |
| Barry, AL; Jones, RN | 1 |
| Wolff, M | 1 |
| Pattyn, SR | 1 |
| Goto, M; Sano, M; Ueda, J; Yamamoto, I; Yamashina, H; Yoshikawa, E | 1 |
| Smith, CR | 1 |
| Hirose, T; Inoue, M; Ito, Y; Kato, H; Mitsuhashi, S; Okezaki, E | 1 |
| Kawane, H; Niki, Y; Soejima, R; Sumi, M; Umeki, S | 1 |
| Fernández-Roblas, R; Ponte, C; Santamaría, M; Soriano, F; Torres, A | 1 |
| Descotes, J; Evreux, JC; Lombard, JY | 1 |
| Benavente, MC; Casal, M; Gonzalez, AI; Rodriguez, F; Villalba, R | 1 |
| Baars, AM; van Herwaarden, CL; Vree, TB; Wijnands, WJ | 2 |
| Borner, K; Glatzel, P; Höffken, G; Koeppe, P; Lode, H; Olschewski, P; Prinzing, C; Reimnitz, D; Sievers, B; Wiley, R | 1 |
| Rugendorff, EW | 1 |
| Akalin, E; Baykal, M | 1 |
| Etienne, D; Fay, M; Forest, N; Gougerot-Pocidalo, MA; Pocidalo, JJ; Roche, Y | 1 |
| Niculescu, E; Wagener, H | 1 |
| Smith, JT | 4 |
| Cynamon, MH; Wilcox, GH | 1 |
| Eggleston, M; Park, SY | 1 |
| Bryskier, A; Husson, MO; Izard, D; Leclerc, H | 1 |
| Bryskier, A; Chantot, JF | 1 |
| Kumada, T; Neu, HC | 1 |
| Bryskier, A; Croize, J; Le Noc, P; Robert, J | 1 |
| Klesel, N; Limbert, M; Seibert, G | 1 |
| Bauernfeind, A; Ullmann, U | 1 |
| Fukuyama, M; Imagawa, Y; Kawakami, K; Suda, O | 1 |
| Bing Hoh, H; Diamond, JP; Easty, DL; Leeming, JP; White, L | 1 |
| Alvarez, R; Arias, A; Felipe, A; Hernández, AM; Sierra, A | 1 |
| Essepian, JP; O'Brien, TP; Rajpal, R | 1 |
| Howard, BM; Pinney, RJ; Smith, JT | 2 |
| Akahane, K; Kimura, Y; Kitano, Y; Tsutomi, Y | 1 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| Fujita, H; Matsuo, I | 1 |
| Hiramatsu, K; Hori, S; Ohshita, Y; Utsui, Y | 1 |
| Beam, TR | 1 |
| Fukuda, M; Murano, H; Sasaki, K | 1 |
| Advikolanu, K; Bruce, AW; Martin, RA; Reid, G; Sharma, S; Tieszer, C | 1 |
| Cho, JK; Han, HJ; Kim, JH; Kim, K; Lee, DS; Park, WB | 1 |
| Mamet, R; Schoenfeld, N | 1 |
| Garcia-Rodriguez, JA; Gomez Garcia, AC | 1 |
| Kivistö, KT; Lehto, P; Neuvonen, PJ | 1 |
| Ichikawa, N; Iwamoto, K; Naora, K | 1 |
| Iakovlev, VP | 1 |
| Griffiths, NM; Hirst, BH; Simmons, NL | 1 |
| Aulicino, T; Donnenfeld, ED; Gombert, ME; Perry, HD; Schrier, A; Snyder, R | 1 |
| Kivistö, KT; Lehto, P | 1 |
| Pfau, A; Sacks, TG | 2 |
| Mizuno, A; Nakashima, M; Uematsu, T | 1 |
| Kobayashi, I; Kumazawa, J; Matsumoto, T; Tanaka, M | 1 |
| Aoki, H; Fujisawa, C; Hakusui, H; Kurata, T; Ohshima, Y; Okazaki, O; Tanaka, M | 1 |
| Akingeneye, J; Bogaerts, J; Mukantabana, V; Piot, P; Tello, WM; Van Dyck, E | 1 |
| Foleno, BD; Fu, KP; Lafredo, SC | 1 |
| Biswas, S; Sharma, AK; Tripathi, KD; Valecha, N | 1 |
| Fukuoka, Y; Ikeda, Y; Narita, H; Takahata, M; Todo, Y; Yamashiro, Y | 1 |
| Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K | 1 |
| Asaoka, T; Imamori, K; Maebashi, K; Matsuda, H; Matsumoto, M; Tahara, Y | 1 |
| Inoue, M; Kobayashi, I; Takahashi, A; Ushijima, Y; Yomoda, S | 1 |
| Ahmedy, A; Khardori, N; Toama, M; Yassien, M | 1 |
| Bow, EJ; Feld, R; Louie, TJ; Mandell, LA; Palmer, M; Pater, J; Zee, B | 1 |
| Mann, RD; Pearce, GL; Wilton, LV | 1 |
| Callegan, MC; Engel, LS; Green, LC; Hill, JM; Jasheway, DW; O'Callaghan, RJ; Shimomura, Y | 1 |
| Chilima, BZ; Okazawa, Y; Tanno, K; Tosaka, M; Yamane, N | 1 |
| Chambers, HF; Hackbarth, CJ; Kocagöz, T; Nikaido, H; Rosenberg, EY; Unsal, I | 1 |
| Itoh, T; Kai, A; Kudoh, Y; Ohta, K; Saito, K; Shingaki, M; Tadano, K; Takahashi, M; Yanagawa, Y | 1 |
| Ballesta, S; García, I; Pascual, A; Perea, EJ | 1 |
| Dai, J; Meatherall, R | 1 |
| Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K | 1 |
| Akkan, AG; Gök, A; Mutlu, I; Ozüner, Z; Ozyazgan, S; Pekel, H; Senses, V; Yigit, U | 2 |
| Mattingly, SJ; Piña, SE | 1 |
| Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H | 1 |
| Deguchi, T; Kawada, Y; Kawamura, T; Nakano, M; Nishino, Y; Ozeki, S; Yasuda, M | 1 |
| Beck, R; Drewelow, B; Fischer, U; Guthoff, R; Hehl, EM; von Keyserlingk, J | 1 |
| Sieb, JP | 1 |
| Shetty, M; Shivananda, PG | 1 |
| Barbosa, J; Bergés, R; Sanz-Nebot, V | 1 |
| Albini, A; Fasani, E; Profumo, A | 1 |
| Ji, B; Lu, M; Ouyang, K | 1 |
| Aeschlimann, JR; Dresser, LD; Kaatz, GW; Rybak, MJ | 1 |
| Beck, R; Drewelow, B; Fischer, U; Guthoff, R; van Keyserlingk, J | 1 |
| Bhaduri, AP; Chauhan, PM; Pandey, VC; Puri, SK; Shukla, A; Srivastava, S; Srivastava, SK | 1 |
| Andreu, M; Coll, S; Gana, J; Guarner, C; Miñana, J; Mirelis, B; Novella, MT; Ortiz, J; Prats, G; Sábat, M; Solá, R; Soriano, G; Vila, MC | 1 |
| Antolic, G; Grabnar, I; Kozjek, F; Mrhar, A; Suturkova, LJ | 1 |
| Fukuda, M; Sasaki, K; Yoshitake, Y | 1 |
| Aeschlimann, JR; Kaatz, GW; Rybak, MJ | 1 |
| Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I | 1 |
| Akagi, M; Fukuishi, N; Kanoh, R; Matsui, N | 1 |
| Bark, KM; Kim, TH; Lee, HC; Lee, JK; Park, HR; Yang, K | 1 |
| Alonso, A; Alós, I; Campanario, E; Martíinez, JL; Sánchez, P | 1 |
| Cai, R; Huang, Z; Liu, Z | 1 |
| Deguchi, T; Fukuda, H; Ishihara, S; Kawada, Y; Yasuda, M; Yokoi, S | 1 |
| Fukuyama, M; Furuhata, K; Hara, T; Oonaka, K; Sunakawa, K | 1 |
| Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H | 1 |
| Castell, JV; Morlière, P; Ouédraogo, G; Santus, R | 1 |
| Abell, S; Chapman, S; Nadin, L; Warren, R | 1 |
| Chen, X; Hooper, B; Hooper, M; Hu, Z; Wu, S; Zhang, W; Zhao, Z | 1 |
| Bonfiglio, G; Cafiso, V; Campanile, F; Messina, C; Santagati, M; Stefani, S | 1 |
| Cranidis, A; Kontoyiannis, DP; Maraki, S; Mavromanolakis, E; Samonis, G; Tselentis, Y | 1 |
| Bai, ZZ; Guan, DW; Zhang, QS | 1 |
| Chuma, T; Ikeda, T; Maeda, T; Niwa, H; Okamoto, K | 1 |
| Chen, J; Chen, RR; Huang, HS | 1 |
| Iwatsu, M; Kanai, A; Sado, K; Tian, X | 1 |
| Piddock, LJ; Ricci, V | 1 |
| Clark, DW; Layton, D; Pearce, GL; Shakir, SA; Wilton, LV | 1 |
| Calvo, A; García, R; Gómez-Lus, ML; Leturia, A; Sevillano, D; Valero, E | 1 |
| Picazo, JJ; Rodríguez-Avial, C; Rodríguez-Avial, I | 1 |
| Miragliotta, G | 1 |
| Stahlmann, R | 1 |
| Schaeffer, AJ | 1 |
| Katouno, Y; Kobayashi, Y; Sugita, K; Uchida, H | 1 |
| Kim, IS; Kim, MR; Lee, CJ; Lee, MH; Shim, JH | 1 |
| Chen, L; Jin, XY; Li, R; Luo, SY; Sun, XG; Wang, ZQ | 1 |
| Ono, C; Tanaka, M | 1 |
| Kawai, M; Mashima, Y; Mochizuki, H; Yamada, K; Yamada, M | 1 |
| Shah, P | 1 |
| Chiang, CH; Lu, DW; Tai, MC | 1 |
| Chuma, T; Maeda, T; Niwa, H; Okamoto, K | 1 |
| Amin, AS; Ragab, GH | 1 |
| Duan, GC; Xi, YL; Zhu, JY | 1 |
| De Neeling, AJ; Geerlings, SE; Hoepelman, AI; Meiland, R | 1 |
| Bagnardi, V; Botteri, E; Carobbio, A; Corrao, G; Falcone, C; Leoni, O; Zambon, A | 1 |
| El-Brashy, AM; El-Sayed Metwally, M; El-Sepai, FA | 1 |
| Köşem, M; Ozbek, H; Tuncay, I; Unal, O | 1 |
| Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A | 1 |
| Abba, M; Donnelly, J; Hussain, B; Shervington, LA | 1 |
| Espinosa-Mansilla, A; Gómez, DG; Peña, AM; Salinas, F | 1 |
| Berti, T; Gianfranceschi, L; Lanzafame, P; Miglioli, PA; Sartore, P | 1 |
| Abd El-Aty, AM; Kuroha, M; Nakamura, M; Regmi, NL; Shimoda, M | 1 |
| Depta, JP; Pichler, WJ; Schmid, DA | 1 |
| Alvarez, AI; Merino, G; Molina, AJ; Prieto, JG; Pulido, MM; Schinkel, AH | 1 |
| Romero, IC; Saravia, NG; Walker, J | 1 |
| Gerkowicz, M; Gruszecka-Gerkowicz, R; Kosior-Jarecka, E; Pietraś-Trzpiel, M | 1 |
| Ishikawa, K; Kawai, M; Mochizuki, H; Yamada, M | 1 |
| Ni, YN; Zhang, GW | 1 |
| Andreeva, I; Rafalsky, V; Rjabkova, E | 1 |
| Abd El-Aty, AM; Kubota, R; Regmi, NL; Shimoda, M; Tomita, A | 1 |
| Li, XD; Liu, YC; Xu, WH; Zhang, G; Zou, SC | 1 |
| Ben, ID; Beringhelli, T; Eberini, I; Fantucci, P; Gaiji, N; Galliano, M; Galluccio, L; Gianazza, E; Maggioni, D; Mazzitello, R; Rocco, AG | 1 |
| Huang, CH; Zhang, H | 1 |
| Baptista, T; de Castro, B; Gameiro, P; Rodrigues, C; Sousa, I | 1 |
| Lee, HB; Peart, TE; Svoboda, ML | 1 |
| Beier, RC; Ding, S; Feng, C; He, F; Jiang, H; Kai, Z; Li, J; Shen, J; Wan, Y; Wang, Z; Yang, X; Zhang, S; Zhu, Y | 1 |
| Alañón Molina, A; Durán Merás, I; Jiménez Girón, A; Muñoz de la Peña, A; Murillo, JA | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Jin, L; Shen, B; Wang, X; Zhao, H | 1 |
| Cao, JT; Liu, YM; Tian, W; Zheng, YL | 1 |
| Larsson, L; Mathiasson, L; Zorita, S | 1 |
| Chen, XF; Li, WY; Xuan, CS | 1 |
| Becnel Boyd, L; Morgan-Linnell, SK; Steffen, D; Zechiedrich, L | 1 |
| Becnel Boyd, L; Hamill, RJ; Horton, LB; Jimenez, JR; Maynard, MJ; Morgan-Linnell, SK; Steffen, D; Sucgang, R; Versalovic, J; Zechiedrich, L | 1 |
| Jia, YX; Liu, YM; Tian, W | 1 |
| Aucelio, RQ; Nava-Júnior, IS | 1 |
| García-Rodríguez, JA; Lázaro, FG; Muñoz-Bellido, JL; Rodríguez-Tarazona, RE | 1 |
| Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M | 1 |
| Lin, B | 1 |
| Chen, WL; Hu, FR; Tsai, TH | 1 |
| Du, S; Kokot, S; Ni, Y | 1 |
| Guo, W; Liu, N; Liu, Y | 1 |
| Conkle, JL; Cook, RL; Lattao, C; White, JR | 1 |
| Alves, G; Falcão, A; Fortuna, A; Lino, C; Pena, A; Sousa, J | 1 |
| Du, J; Liu, B; Qin, X; Wang, H; Yan, H | 1 |
| Kaczmarek, M; Lis, S | 1 |
| Beytemur, O; Gulmez, T; Kaleagasioglu, F; Mutlu, Z; Olcay, E; Olgac, V | 1 |
| Alliot, F; Chevreuil, M; Dinh, QT; Eurin, J; Labadie, P; Moreau-Guigon, E | 1 |
| Herodes, K; Kipper, K; Leito, I; Nei, L | 1 |
| Menchini, U; Mencucci, R; Paladini, I; Pellegrini-Giampietro, DE; Scartabelli, T | 1 |
| Jia, CL; Lv, YK; Ma, Y; Sun, HW; Zhao, XB | 1 |
| Aznar, J; Iraurgui, P; Torres, MJ | 1 |
| Liu, M; Xia, Q; Yang, Y | 1 |
| Ayaki, M; Iwasawa, A; Niwano, Y | 1 |
| Liu, Y; Pan, B; Peng, H; Wu, M; Xing, B; Zhang, D | 1 |
| Giester, G; Perdih, F; Psomas, G; Turel, I; Živec, P | 1 |
| Arnold, WA; Korte, AR; Lundeen, RA; McNeill, K; Sundberg, JE; Wammer, KH | 1 |
| Balaji, K; Pandian, SK; Thenmozhi, R | 1 |
| Nakada, N; Narumiya, M; Tanaka, H; Yamashita, N | 1 |
| Amorim, CL; Castro, PM; Maia, AS; Moreira, IS; Tiritan, ME | 1 |
| Amorim, CL; Castro, PM; Maia, AS; Mesquita, RB; Rangel, AO; Tiritan, ME; van Loosdrecht, MC | 1 |
| Li, H; Pan, B; Peng, H; Wang, C; Xing, B; Zhang, D | 1 |
| Amorim, CL; Barreiro, JC; Cass, QB; Castro, PM; Maia, AS; Ribeiro, AR; Tiritan, ME | 1 |
| Chen, X; Han, F; Hu, Y; Lü, Y; Qiu, J; Song, W; Zheng, P; Zhou, F; Zhou, X | 1 |
| Cajthaml, T; Čvančarová, M; Filipová, A; Moeder, M | 1 |
| Cui, YF; He, JT; Qiao, XC; Su, SH; Yang, L | 2 |
| Chen, F; Li, H; Liang, N; Pan, B; Peng, H; Xing, B; Zhang, D | 1 |
| Kang, H; Lin, L; Luo, Y; Tu, X; Wu, W; Xie, L; Yue, Z; Zhang, Y | 1 |
| Cass, QB; Denadai, M | 1 |
| Chen, T; Liu, S; Shi, W; Tao, H; Wang, Y; Xu, Y | 1 |
| Chaminda, GT; Chiemchaisri, C; Chiemchaisri, W; Chulasak, R; Furumai, H; Honda, R; Masago, Y; Poonnotok, A; Sawaittayotin, V; Sienglum, C; Sunthonwatthanaphong, V; Tanong, K; Watanabe, T; Wongsila, K; Yamamoto, K | 1 |
| Dang, Z; Huang, RP; Liu, ZH; Yin, H; Yuan, SF | 1 |
| Li, H; Liang, N; Pan, B; Wu, M; Zhang, D; Zheng, N | 1 |
| Hollert, H; Kueppers, S; Santiago-Schübel, B; Xiao, H; Zhu, L | 1 |
| Chen, G; Li, M; Liu, X; Tartakevosky, D | 1 |
| Dai, LL; Dai, XH; Li, N; Liu, HJ; Xue, YG; Yan, H | 1 |
| Alaboud, M; Bulatov, A; Korolev, D; Lebedinets, S; Moskvin, L; Osmolovskaya, O; Postnov, V; Vakh, C | 1 |
| Cao, J; Cen, Y; Ding, Y; Hu, Y; Huang, J; Tang, H | 1 |
| Hai, RT; Li, J; Li, XH; Wang, XH; Zheng, Q | 1 |
| Kurz, X; McGettigan, P; Morales, D; Pacurariu, A; Pinheiro, L; Slattery, J | 1 |
| Cui, P; Ding, YF; Liu, SC; Sun, SJ | 1 |
| Bandyopadhyay, B; Giri, N; Roy, B; Tousif Ahamed, SK | 1 |
| Chongsuvivatwong, V; McNeil, E; Sangthong, R; Tang, R; Xu, J | 1 |
| Arun, S; Chakraborty, P; Ilango, K; Kumar, RM; Mukhopadhyay, M; Ruppa, J | 1 |
| Chang, C; Chen, T; Li, J; Liu, F; Lu, X; Niwa, O; Wang, Q; Xue, Q; Zhou, T | 1 |
| Bucsa, C; Farcas, A; Huruba, M; Leucuta, DC; Mogosan, C; Sipos, M | 1 |
| Hu, E; Li, M; Liu, S; Sun, C; Wen, L; Yang, F | 1 |
| Du, H; Li, J; Li, Z; Yang, Y; Zhong, Z | 1 |
| Guan, S; Huang, B; Li, P; Lin, G; Luan, T; Wang, Y; Yuan, K | 1 |
| Bai, H; Chen, J; Gao, FZ; He, LX; He, LY; Hu, LX; Liu, YS; Yang, YY; Ying, GG; Zhao, JL | 1 |
| Cao, Z; Li, X; Lu, Y; Mao, R; Song, S; Sun, B; Wang, C; Wang, R; Zhang, M | 1 |
| Gao, Y; Ji, Y; Lin, Y; Lin, Z; Lu, Y; Yang, Y; Zhang, L | 1 |
| Yu, Z; Zhang, J; Zheng, Y | 1 |
| Elakiya, BT; Rajamohan, N; Ramkumar, V; Singaramohan, D; Sivaprakash, B | 1 |
| Chen, Y; Cui, K; Ding, Y; Liu, X; Qin, X | 1 |
| Adhikary, A; Biswal, S; Chatterjee, D; Ghosh, AS | 1 |
| Cruz-Monzon, J; De La Cruz-Noriega, M; Gallozzo Cardenas, M; Gamez-Jara, A; Rodríguez-Serin, H; Rodriguez-Yupanqui, M; Rojas-Flores, S | 1 |
| Guo, L; Kuang, H; Lei, X; Liu, L; Xu, C; Xu, L | 1 |
| El-Sayed, SAE; Igarashi, I; Rizk, MA | 1 |
| Li, F; Qian, S; Wang, Q; Zhao, K | 1 |
| Dong, J; Ji, Y; Kong, D; Lu, J; Zhang, C; Zhang, T; Zhou, Q | 1 |
| Han, Z; Li, Y; Lyu, C; Zhao, L; Zhou, M | 1 |
| Chakraborty, P; Karayi, M; Neppolian, B; Yazhini, C | 1 |
| Dong, D; Guo, Z; He, S; Li, Z; Sun, H; Sun, Z; Wang, Y; Zhang, J; Zhang, L | 1 |
| Acuña-Askar, K; Guzmán-Mar, JL; Larralde-Piña, IA; Murillo-Sierra, JC; Ruiz-Ruiz, EJ; Villanueva-Rodríguez, M | 1 |
| Cai, C; Chen, R; Dai, X; Dong, B; Xiao, T; Xu, Z; Yuan, S | 1 |
24 review(s) available for ofloxacin and norfloxacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Quinolone antibiotics.
Topics: | 2019 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Safety profile of quinolones.
Topics: Animals; Ciprofloxacin; Dogs; Drug Tolerance; Humans; Male; Norfloxacin; Ofloxacin; Rats | 1990 |
Norfloxacin, ciprofloxacin, and ofloxacin: current clinical roles.
Topics: Bacteria; Bacterial Infections; Ciprofloxacin; Drug Tolerance; Humans; Norfloxacin; Ofloxacin | 1989 |
Action of quinolones on gene expression and bacterial membranes.
Topics: Animals; Anti-Bacterial Agents; Cell Membrane; Ciprofloxacin; Gene Expression Regulation; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; SOS Response, Genetics; Topoisomerase II Inhibitors | 1987 |
The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.
Topics: Anti-Bacterial Agents; Bacteria; Blood Proteins; Ciprofloxacin; Enoxacin; Fluorine; Humans; Kidney; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding; Quinolines; Urinary Tract Infections | 1985 |
A review on the impact of 4-quinolones on the normal oropharyngeal and intestinal human microflora.
Topics: Ciprofloxacin; Enoxacin; Humans; Intestines; Naphthyridines; Norfloxacin; Ofloxacin; Oropharynx; Oxazines; Pefloxacin; Quinolines | 1988 |
Pharmacokinetics of ciprofloxacin.
Topics: Anti-Infective Agents; Biological Availability; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Tissue Distribution | 1988 |
[Refractory respiratory tract infections. 7. Trends in the development of new chemotherapeutic agents for respiratory tract infections. b. Synthetic antibacterial agents].
Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Quinolines; Respiratory Tract Infections | 1987 |
Symposium on antimicrobial agents. The quinolones.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Humans; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
Quinolones.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
The mode of action of 4-quinolones and possible mechanisms of resistance.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
New antibiotics: areas of appropriate use.
Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Infections; beta-Lactamase Inhibitors; Cephalosporins; Ciprofloxacin; Enoxacin; Humans; Imipenem; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Thienamycins | 1987 |
The role of 4-quinolones in the treatment of infections.
Topics: Bacterial Infections; Ciprofloxacin; Humans; Kinetics; Norfloxacin; Ofloxacin; Oxazines; Urinary Tract Infections | 1987 |
Review of the 4-quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enoxacin; Humans; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
Quinolone therapy in intensive care unit settings.
Topics: Administration, Oral; Aged; Ciprofloxacin; Clinical Protocols; Clinical Trials as Topic; Cross Infection; Drug Interactions; Drug Resistance, Microbial; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Tissue Distribution | 1993 |
In-vitro activities of quinolones against mycobacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Mycobacterium leprae; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin | 1993 |
[Pharmacokinetics of fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin | 1993 |
Fluoroquinolones reviewed.
Topics: Adult; Anti-Infective Agents; Child; Ciprofloxacin; Clinical Trials as Topic; Female; Humans; Norfloxacin; Ofloxacin; Urinary Tract Infections | 1993 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
Literature Review: Evaluation of Drug Removal Techniques in Municipal and Hospital Wastewater.
Topics: Anti-Bacterial Agents; Carbamazepine; Diclofenac; Hospitals; Naproxen; Norfloxacin; Ofloxacin; Ozone; Pharmaceutical Preparations; Sewage; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2022 |
13 trial(s) available for ofloxacin and norfloxacin
| Article | Year |
|---|---|
4-quinolones inhibit biotransformation of caffeine.
Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline | 1988 |
[Diffusion of fluoroquinolones in the aqueous humor and crystalline lens].
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Diffusion; Humans; Lens, Crystalline; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections.
Topics: Adult; Anti-Infective Agents; Bacteriuria; Female; Humans; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Random Allocation; Urinary Tract Infections | 1987 |
The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.
Topics: Absorption; Adult; Ciprofloxacin; Drug Interactions; Female; Ferrous Compounds; Humans; Male; Norfloxacin; Ofloxacin; Software | 1994 |
Penetration of topically applied ciprofloxacin, norfloxacin, and ofloxacin into the aqueous humor.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aqueous Humor; Biological Assay; Biological Availability; Cataract Extraction; Ciprofloxacin; Female; Humans; Lenses, Intraocular; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1994 |
Effect of sucralfate on absorption of norfloxacin and ofloxacin.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Drug Administration Schedule; Drug Interactions; Female; Humans; Male; Norfloxacin; Ofloxacin; Sucralfate | 1994 |
Effective postcoital quinolone prophylaxis of recurrent urinary tract infections in women.
Topics: Adult; Ciprofloxacin; Coitus; Female; Humans; Norfloxacin; Ofloxacin; Prospective Studies; Recurrence; Urinary Tract Infections | 1994 |
Single dose quinolone treatment in acute uncomplicated urinary tract infection in women.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ciprofloxacin; Female; Gram-Negative Bacterial Infections; Humans; Menopause; Middle Aged; Norfloxacin; Ofloxacin; Prospective Studies; Urinary Tract Infections | 1993 |
Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. National Cancer Institute of Canada Clinical Trials Group.
Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Bacteremia; Colony Count, Microbial; Female; Humans; Male; Middle Aged; Neutropenia; Norfloxacin; Ofloxacin; Rifampin; Staphylococcal Infections; Streptococcal Infections; Treatment Outcome | 1996 |
Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Eye; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Tears | 1997 |
Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor of the uninflamed human eye.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aqueous Humor; Cataract Extraction; Ciprofloxacin; Eye Infections; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1997 |
Kinetics of 4-fluoroquinolones permeation into saliva.
Topics: Adult; Anti-Infective Agents; Biological Transport; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Monitoring; Humans; Male; Norfloxacin; Ofloxacin; Pefloxacin; Saliva | 1999 |
[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation].
Topics: Antibiotic Prophylaxis; Cataract; Cataract Extraction; Chloramphenicol; Conjunctiva; Conjunctivitis, Bacterial; Female; Gentamicins; Humans; Male; Norfloxacin; Ofloxacin | 2005 |
408 other study(ies) available for ofloxacin and norfloxacin
| Article | Year |
|---|---|
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity.
Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship | 1992 |
Quinolone antibacterial agents substituted at the 7-position with spiroamines. Synthesis and structure-activity relationships.
Topics: Bacteria; Chemical Phenomena; Chemistry; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Structure; Piperazines; Pyrrolidines; Quinolines; Spiro Compounds; Structure-Activity Relationship | 1990 |
Chiral DNA gyrase inhibitors. 2. Asymmetric synthesis and biological activity of the enantiomers of 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H- pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid (ofloxacin).
Topics: Anti-Bacterial Agents; Ofloxacin; Oxazines; Stereoisomerism; Topoisomerase II Inhibitors | 1987 |
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay.
Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity.
Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Quinolonecarboxylic acids. 2. Synthesis and antibacterial evaluation of 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acids.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pyridones; Spectrophotometry, Infrared; Thiazines | 1987 |
Quinolone antimicrobial agents substituted with morpholines at the 7-position. Syntheses and structure-activity relationships.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Escherichia coli; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Morpholines; Quinolones; Staphylococcus aureus; Structure-Activity Relationship | 1993 |
Synthesis of antimicrobial agents. 5. In vivo metabolism of 7-(4-hydroxypiperazin-1-yl)quinolones.
Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Mice; Microbial Sensitivity Tests; Piperazines; Rats; Structure-Activity Relationship | 1993 |
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1.
Topics: Animals; Anion Transport Proteins; Anti-Bacterial Agents; Biological Transport; Carrier Proteins; Cell Survival; Cephaloridine; Cephalosporins; In Vitro Techniques; Kidney; Kinetics; Oocytes; p-Aminohippuric Acid; Penicillin G; Rats; Recombinant Proteins; Xenopus laevis | 1999 |
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Culture Media; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Indicators and Reagents; Kinetics; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Omeprazole; Staphylococcus aureus; Structure-Activity Relationship | 2007 |
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal | 2007 |
Vibrio splendidus as the source of plasmid-mediated QnrS-like quinolone resistance determinants.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Open Reading Frames; Plasmids; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Vibrio | 2007 |
Plasmid-mediated quinolone resistance determinant QnrB4 identified in France in an Enterobacter cloacae clinical isolate coexpressing a QnrS1 determinant.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacter cloacae; Escherichia coli; France; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Plasmids; Quinolones; Transformation, Genetic | 2007 |
Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms.
Topics: Animals; Anti-Bacterial Agents; Biofilms; CHO Cells; Cricetinae; Cricetulus; DNA-Directed RNA Polymerases; Furans; Gram-Positive Bacteria; Microbial Sensitivity Tests; Rhodanine; Staphylococcus epidermidis; Structure-Activity Relationship | 2007 |
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Novobiocin; Ofloxacin; Piperacillin; Polyethyleneimine; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Ticarcillin; Tobramycin | 2008 |
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey | 2008 |
ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli.
Topics: Base Sequence; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Quinolones | 2008 |
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Cattle; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Quinolones; Salmonella enterica | 2009 |
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei | 2009 |
Characterization of the plasmid-borne quinolone resistance gene qnrB19 in Salmonella enterica serovar Typhimurium.
Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Evolution, Molecular; Microbial Sensitivity Tests; Multigene Family; Plasmids; Quinolones; Salmonella typhimurium | 2009 |
Interaction of drug based binuclear mixed-ligand complexes with DNA.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity | 2009 |
Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype.
Topics: Bacterial Proteins; Drug Resistance, Bacterial; Electroporation; Genotype; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella enterica | 2009 |
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens | 2009 |
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.
Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes | 2010 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2010 |
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Novel variants of the qnrB gene, qnrB22 and qnrB23, in Citrobacter werkmanii and Citrobacter freundii.
Topics: Animals; Bacterial Proteins; Chickens; Citrobacter; Citrobacter freundii; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Quinolones; Swine | 2010 |
The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Burkholderia pseudomallei; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Periplasmic Proteins; Quorum Sensing; Singapore; Virulence Factors | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Antimicrobial activity of imidazo[1,5-a]quinoxaline derivatives with pyridinium moiety.
Topics: Animals; Anti-Infective Agents; Bacteria; Drug Design; Female; Fungi; Imidazoles; Male; Mice; Microbial Sensitivity Tests; Pyridinium Compounds | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Design, synthesis, and biological evaluation of dihydroartemisinin-fluoroquinolone conjugates as a novel type of potential antitubercular agents.
Topics: Antitubercular Agents; Artemisinins; Drug Design; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2014 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies | 2014 |
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins | 2014 |
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship | 2014 |
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi | 2015 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Synthesis and biological evaluation of 1-amino isochromans from 2-bromoethyl benzaldehyde and amines in acid medium.
Topics: Acetic Acid; Amines; Anti-Bacterial Agents; Bacillus subtilis; Benzaldehydes; Chromans; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship | 2018 |
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indoles; Molecular Structure; Piperidines; Structure-Activity Relationship | 2018 |
Design of Trp-Rich Dodecapeptides with Broad-Spectrum Antimicrobial Potency and Membrane-Disruptive Mechanism.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacterial Outer Membrane; Drug Design; Escherichia coli; Humans; Microbial Sensitivity Tests; Oligopeptides; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcus aureus; Tryptophan | 2019 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine | 2019 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
[Comparative activities in vitro of 4 quinolones (nalidixic acid, pefloxacin, norfloxacin, ofloxacin) on 13 bacterial species].
Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Species Specificity | 1992 |
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
[In vitro antimicrobial activities of new quinolone antibiotics against Mycoplasma pneumoniae].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Macrolides; Mycoplasma pneumoniae; Norfloxacin; Ofloxacin; Quinolones; Tetracyclines | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
[Influence of new quinolones on superoxide anion generation of polymorphonuclear leukocytes].
Topics: Ciprofloxacin; Enoxacin; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Superoxides | 1992 |
In vitro activity of CP-74667 compared with four other fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro activity of l-ofloxacin against norfloxacin-resistant coagulase-negative staphylococci.
Topics: Anti-Bacterial Agents; Coagulase; Drug Resistance, Microbial; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus | 1992 |
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Tissue Distribution | 1992 |
Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus | 1992 |
Effect of fenbufen on the entry of new quinolones, norfloxacin and ofloxacin, into the central nervous system in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Brain; Male; Norfloxacin; Ofloxacin; Phenylbutyrates; Protein Binding; Rats; Rats, Wistar | 1992 |
OmpF channel permeability of quinolones and their comparison with beta-lactams.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Cell Membrane Permeability; Cephalosporins; Diffusion; Enoxacin; Escherichia coli; Liposomes; Nalidixic Acid; Norfloxacin; Ofloxacin; Stereoisomerism | 1992 |
Determination of ofloxacin in human serum by high-performance liquid chromatography with column switching.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Humans; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Spectrophotometry, Ultraviolet | 1992 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
[Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders].
Topics: Animals; Ciprofloxacin; Cricetinae; Drug Resistance, Microbial; Glanders; Guinea Pigs; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pseudomonas | 1991 |
In vitro susceptibility of Francisella tularensis to fluoroquinolones and treatment of tularemia with norfloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Francisella tularensis; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Tularemia | 1991 |
Streptococcus sanguis survival in K-Sol. Comparison of gentamicin and the fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Chondroitin Sulfates; Ciprofloxacin; Colony Count, Microbial; Gentamicins; HEPES; Norfloxacin; Ofloxacin; Streptococcus sanguis | 1991 |
Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; DNA; DNA Repair; Liver; Norfloxacin; Ofloxacin; Pefloxacin; Phosphorus Radioisotopes; Rats | 1991 |
Chlamydia trachomatis: in vitro susceptibility of genital and ocular isolates to some quinolones, amoxicillin and azithromycin.
Topics: Amoxicillin; Anti-Infective Agents; Azithromycin; Cervix Uteri; Chlamydia trachomatis; Ciprofloxacin; Conjunctiva; Drug Evaluation, Preclinical; Erythromycin; Female; Humans; Infant, Newborn; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Urethra | 1990 |
In vitro and in vivo antibacterial activities of E-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Fluoroquinolones; Magnesium; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1991 |
[Antibacterial activity of ciprofloxacin against fresh clinical isolates from superficial suppurative foci].
Topics: Amoxicillin; Bacteria; Cefaclor; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Suppuration | 1991 |
Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cell Survival; Ciprofloxacin; Enoxacin; HIV-1; Humans; Lymphocytes; Norfloxacin; Ofloxacin | 1990 |
Influence of new quinolones on normal immune capabilities.
Topics: Animals; Anti-Infective Agents; Antibody Formation; Ciprofloxacin; Hypersensitivity, Delayed; Immunity, Cellular; Injections, Intramuscular; Male; Mice; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis | 1990 |
Quinolone pharmacokinetics and metabolism.
Topics: Administration, Oral; Anti-Infective Agents; Biological Availability; Biotransformation; Ciprofloxacin; Enoxacin; Fleroxacin; Half-Life; Humans; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Topics: Adult; Animals; Brain Chemistry; Ciprofloxacin; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Humans; In Vitro Techniques; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Radioligand Assay; Random Allocation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1990 |
Pharmacokinetic determination of relative potency of quinolone inhibition of caffeine disposition.
Topics: Caffeine; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Male; Models, Biological; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones | 1990 |
[In vitro activity of 4 fluoroquinolones against Klebsiella pneumoniae. Distribution according to phenotype resistance to aminoglycosides or beta-lactams].
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; In Vitro Techniques; Klebsiella pneumoniae; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype | 1990 |
Intracellular activity of tosufloxacin (T-3262) against Salmonella enteritidis and ability to penetrate into tissue culture cells of human origin.
Topics: Anti-Infective Agents; Cell Line; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Salmonella enteritidis | 1990 |
The influence of quinolones on the faecal flora.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Feces; Humans; Intestines; Norfloxacin; Ofloxacin; Pefloxacin | 1990 |
The pharmacokinetics of oral quinolones (norfloxacin, ciprofloxacin, ofloxacin).
Topics: Administration, Oral; Ciprofloxacin; Half-Life; Humans; Intestinal Absorption; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Time Factors | 1990 |
Comparison of inhibitory effects of new quinolones on drug metabolizing activity in the liver.
Topics: Acetaminophen; Animals; Anti-Infective Agents; Enoxacin; Glutathione; Liver; Liver Function Tests; Male; Microsomes, Liver; Mixed Function Oxygenases; Norfloxacin; Ofloxacin; Rats; Theophylline | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
[Antibacterial activity of norfloxacin, ofloxacin and ciprofloxacin according to resistance phenotypes to nalidixic acid and pefloxacin].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Aerobic Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype; Staphylococcus aureus | 1990 |
The in vitro activity of norfloxacin, ofloxacin and ciprofloxacin and other antibiotics in current use against Neisseria gonorrhoeae.
Topics: Ampicillin; Ampicillin Resistance; Ciprofloxacin; Doxycycline; Drug Resistance, Microbial; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Penicillin Resistance | 1989 |
[Activity of 5 fluoroquinolones on hospital Gram-negative bacilli with different sensitivities to pefloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Pseudomonas aeruginosa; Serratia marcescens | 1989 |
In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Phenalenes; Quinolones | 1989 |
[Fluoroquinolones--antibacterial activity, pharmacokinetics and indications for a new group of chemotherapeutic drugs].
Topics: Adult; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin | 1989 |
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial Sensitivity Tests; Neutropenia; Norfloxacin; Ofloxacin; Pipemidic Acid; Time Factors; Urinary Tract Infections; Uterus | 1989 |
Inhibitory effect of enoxacin, ofloxacin and norfloxacin on renal excretion of theophylline in humans.
Topics: Adult; Drug Interactions; Enoxacin; Female; Humans; Kidney; Male; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Theophylline | 1989 |
[In vitro determination of the sensitivity of mycobacteria to fluoroquinolones].
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Mycobacterium; Norfloxacin; Ofloxacin; Pefloxacin | 1989 |
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Lung Diseases; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Skin Diseases, Infectious; Urinary Tract Infections | 1989 |
In-vitro synergistic activity between ethambutol and fluorinated quinolones against Mycobacterium avium complex.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Norfloxacin; Ofloxacin | 1989 |
The role of quinolones in staphylococcal infection.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin; Staphylococcal Infections | 1989 |
[Gyrase inhibitors modify metabolising processes in the liver].
Topics: Caffeine; Ciprofloxacin; DNA Topoisomerases, Type II; Enoxacin; Humans; Liver; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Topoisomerase II Inhibitors | 1987 |
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors | 1988 |
Clinical use of the quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Osteomyelitis; Oxazines; Pefloxacin; Quinolines; Respiratory Tract Infections; Sexually Transmitted Diseases; Surgical Wound Infection; Urinary Tract Infections | 1987 |
Susceptibility of Bordetella pertussis to five quinolone antimicrobic drugs.
Topics: Anti-Bacterial Agents; Bordetella pertussis; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Whooping Cough | 1987 |
The comparative in vitro activity of ofloxacin (RU 43 280) and other quinolone derivatives against 722 bacteria of clinical interest.
Topics: Bacteria; Bacteroides fragilis; Clostridium perfringens; Enterobacteriaceae; Fusobacterium; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Structure-Activity Relationship | 1987 |
In vitro activities of ciprofloxacin, ofloxacin, norfloxacin and rosoxacin compared with cinoxacin and trimethoprim.
Topics: 4-Quinolones; Acinetobacter; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cinoxacin; Ciprofloxacin; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Quinolones; Trimethoprim | 1985 |
Effect of ciprofloxacin on phagocytosis.
Topics: Chemotaxis, Leukocyte; Ciprofloxacin; Humans; Luminescent Measurements; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Phagocytosis; Providencia; Quinolines; Staphylococcus aureus | 1985 |
[New oral quinolone compounds in chronic bronchitis].
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; Middle Aged; Naphthyridines; Neisseria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pneumococcal Infections; Pseudomonas Infections; Quinolines; Streptococcus pneumoniae | 1986 |
Quantitative determination of ofloxacin, ciprofloxacin, norfloxacin and pefloxacin in serum by high pressure liquid chromatography.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Spectrophotometry, Ultraviolet | 1986 |
Comparative in vitro activities of ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin against Bacteroides fragilis and Clostridium difficile.
Topics: Anti-Bacterial Agents; Bacteroides fragilis; Ciprofloxacin; Clostridium; Enoxacin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
The action of quinolone carboxylic acids on Chlamydia trachomatis in vitro.
Topics: Animals; Carboxylic Acids; Cells, Cultured; Chlamydia trachomatis; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
In-vitro activity of newer quinolones against aerobic bacteria.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Calcium; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Magnesium Sulfate; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas; Quinolines; Sulfates; Zinc; Zinc Sulfate | 1986 |
In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Methicillin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperazines; Quinolines; Staphylococcus aureus | 1986 |
Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile.
Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Clostridium; Enoxacin; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1986 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
Influence of pH and human urine on the antibacterial activity of ciprofloxacin, norfloxacin and ofloxacin.
Topics: Ciprofloxacin; Escherichia coli; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Urine | 1985 |
Assessment of the in vitro and in vivo activity of ciprofloxacin measured against current standards of therapy.
Topics: Ampicillin; Animals; Azlocillin; Blood; Ciprofloxacin; Escherichia coli; Humans; In Vitro Techniques; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Sisomicin; Tobramycin | 1985 |
Comparative antimicrobial activity of enoxacin, ciprofloxacin, amifloxacin, norfloxacin and ofloxacin against 177 bacterial isolates.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines | 1986 |
In vitro evaluation of A-56619 and A-56620, two new quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Piperazines; Quinolines | 1986 |
In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Male; Mice; Mice, Inbred ICR; Norfloxacin; Ofloxacin; Oxazines; Pneumonia; Quinolines; Urinary Tract Infections | 1986 |
Determination of ciprofloxacine, norfloxacine, and ofloxacine by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1986 |
Photoonycholysis induced by the fluoroquinolones pefloxacine and ofloxacine. Report on 2 cases.
Topics: Aged; Aged, 80 and over; Drug Eruptions; Humans; Male; Mycosis Fungoides; Nail Diseases; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Photosensitivity Disorders; PUVA Therapy | 1986 |
Drug-induced photo-onycholysis. Three subtypes identified in a study of 15 cases.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Doxycycline; Drug Eruptions; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Photosensitivity Disorders; PUVA Therapy; Tetracycline; Trioxsalen; Ultraviolet Rays | 1987 |
[In vitro activity of seven gyrase inhibitors of a group of heterocyclic carbonic acids against nonfermenting gram negative rods (nonfermenters)].
Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Aerobic Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas aeruginosa; Quinolines; Topoisomerase II Inhibitors | 1985 |
[Biotransformation of selected gyrase inhibitors].
Topics: Anti-Infective Agents; Biotransformation; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1986 |
Clinical uses of nalidixic acid analogues: the fluoroquinolones.
Topics: Administration, Oral; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Male; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Topoisomerase II Inhibitors | 1986 |
Inhibition of DNA gyrase by optically active ofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Electrophoresis, Agar Gel; Escherichia coli; Micrococcus; Norfloxacin; Ofloxacin; Oxazines; Topoisomerase II Inhibitors | 1987 |
[Resistance against new gyrase inhibitors--1985/86].
Topics: Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Topoisomerase II Inhibitors | 1987 |
[Rickettsiaceae infections and fluoroquinolones].
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Boutonneuse Fever; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pregnancy; Q Fever; Rifampin | 1988 |
Activity of ofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Anti-Bacterial Agents; Dapsone; Female; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Prothionamide | 1988 |
[Single day treatment in acute cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cystitis; Drug Administration Schedule; Drug Combinations; Escherichia coli Infections; Female; Humans; Middle Aged; Norfloxacin; Ofloxacin; Recurrence; Staphylococcal Infections; Staphylococcus epidermidis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Endogenous active efflux of norfloxacin in susceptible Escherichia coli.
Topics: Anti-Infective Agents; Biological Transport, Active; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Enoxacin; Escherichia coli; Kinetics; Norfloxacin; Ofloxacin; Spheroplasts | 1988 |
Penetrability of ofloxacin into cultured epithelial cells and macrophages.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Ciprofloxacin; Epithelium; HeLa Cells; Macrophages; Male; Norfloxacin; Ofloxacin; Salmonella typhimurium; Shigella | 1988 |
Inhibition of plasmid conjugation by some recently synthetized 4-quinolone compounds.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; R Factors | 1988 |
[Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Staphylococcus aureus | 1986 |
Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis.
Topics: Adult; Anti-Infective Agents; DNA; Humans; In Vitro Techniques; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Piromidic Acid | 1986 |
[In vitro activity of new quinolones against nonfermenters and references to sensitivity tests].
Topics: Acinetobacter; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Immunodiffusion; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas | 1986 |
In vitro activity of A-56619 (difloxacin), A-56620, and other new quinolone antimicrobial agents against genital pathogens.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Female; Fluoroquinolones; Gardnerella vaginalis; Genitalia; Haemophilus; Haemophilus ducreyi; Humans; Male; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Oxazines; Ureaplasma | 1986 |
In vitro activity of RO 23-6240 (AM-833): a new fluoroquinolone.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in-vitro activity of five fluoroquinolones against mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Mycobacterium; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; Naphthyridines; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
[In vitro antibacterial activity of new derivatives of pyridonecarboxylic acid, norfloxacin, ofloxacin, enoxacin and ciprofloxacin, against Vibrio cholerae O-1].
Topics: Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Vibrio cholerae | 1987 |
[In vitro and in vivo activities of norfloxacin, ofloxacin and ciprofloxacin against various mycobacteria].
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Mice; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1987 |
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria].
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1987 |
Comparative in vitro activity of RO 23-6240 (fleroxacin), a new 4-quinolone derivative.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enterobacteriaceae; Enterococcus faecalis; Fleroxacin; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Staphylococcus | 1987 |
Membrane permeability of Pseudomonas aeruginosa to 4-quinolones.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Polymyxin B; Pseudomonas aeruginosa; Quinolines | 1987 |
Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1987 |
In vitro activity of five new quinolones against cultivable mycobacteria.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of four fluoroquinolones against eighty-six isolates of mycobacteria.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Enhancement of interleukin 2 production by quinolone-treated human mononuclear leukocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; In Vitro Techniques; Interleukin-2; Kinetics; Leukocytes, Mononuclear; Lymphocyte Activation; Mitomycin; Mitomycins; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Receptors, Immunologic; Receptors, Interleukin-2 | 1988 |
In vitro activity of three fluoroquinolones against enterococci and Pseudomonas aeruginosa: modified categorization system for discrepant broth dilution and agar disk diffusion test results.
Topics: Ciprofloxacin; Drug Evaluation, Preclinical; Immunodiffusion; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Streptococcus | 1988 |
[In vitro antibacterial activity of piperacillin/quinolone combinations].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens | 1988 |
[Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus].
Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Penicillin G; Vancomycin | 1988 |
[Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis].
Topics: Ciprofloxacin; Drug Synergism; Enterococcus faecalis; Fosfomycin; Microbial Sensitivity Tests; Netilmicin; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Vancomycin | 1988 |
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Enoxacin; Female; Humans; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Peptides, Cyclic; Pipemidic Acid; Rifampin; Tetracycline; Tetracycline Resistance; Urinary Tract Infections; Vancomycin; Virginiamycin | 1988 |
[Sensitivity of 7 mycobacterial species to new quinolones].
Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Drug Synergism; Erythromycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sulfamethoxazole; Thienamycins; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Mycoplasmataceae; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Quinolones; Ureaplasma | 1988 |
[Trends of fluoroquinolone-resistant strains isolated from clinical materials].
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin | 1988 |
Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
Antibacterial activity after a single-dose of norfloxacin, ofloxacin and pipemidic acid detected in urine of volunteers.
Topics: Adult; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella; Male; Nicotinic Acids; Norfloxacin; Ofloxacin; Pipemidic Acid; Proteus mirabilis; Pseudomonas aeruginosa; Time Factors | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
In vitro susceptibility of urinary pathogens to quinolones compared to other antimicrobial agents.
Topics: Anti-Bacterial Agents; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Urinary Tract Infections | 1987 |
Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants.
Topics: Acinetobacter; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Gentamicins; Haemophilus influenzae; Mezlocillin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus | 1985 |
Comparative in vitro activity of three new quinolone antibiotics against recent clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus | 1985 |
Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens.
Topics: Anti-Bacterial Agents; Aztreonam; Cefpirome; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Leucomycins; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1985 |
Antichlamydial activity of quinolone carboxylic acids.
Topics: Chlamydia trachomatis; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1985 |
[Effect ofloxacin on Haemophilus influenza, Streptococcus pneumoniae and Neisseria meningitidis. Comparison with similar molecules].
Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Haemophilus influenzae; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria meningitidis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Streptococcus pneumoniae | 1985 |
[Comparison of the in vitro activity of 6 quinolones on Pseudomonas sp].
Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Pseudomonas; Pseudomonas aeruginosa; Quinolines | 1985 |
[Comparative in vitro study of the activity of 5 quinolones against Acinetobacter calcoaceticus].
Topics: Acinetobacter; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1985 |
[Sensitivity of obligate anaerobes to ofloxacin, pefloxacin, enoxacin and norfloxacin].
Topics: Bacteria, Anaerobic; Bacteroides; Clostridium; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1985 |
Do quinolones bind to DNA?
Topics: Animals; Dialysis; DNA; In Vitro Techniques; Norfloxacin; Ofloxacin; Oxazines; Spectrometry, Fluorescence | 1988 |
In vitro antibacterial activity of imipenem in combination with newer quinolone derivatives.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Microbial; Humans; Imipenem; Norfloxacin; Ofloxacin; Oxazines; Thienamycins | 1988 |
Effect of new quinolones on drug-metabolizing enzyme system of rat hepatic microsomes.
Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Enoxacin; Male; Microsomes, Liver; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Rats; Rats, Inbred Strains | 1988 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Effects of enoxacin, ofloxacin and norfloxacin on theophylline disposition in humans.
Topics: 17-Hydroxycorticosteroids; Adult; Aminophylline; Enoxacin; Female; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Theophylline | 1988 |
[Comparison of enoxacin, ofloxacin, and norfloxacin concentration in human benign prostatic tissue].
Topics: Administration, Oral; Enoxacin; Humans; Male; Norfloxacin; Ofloxacin; Prostate; Tissue Distribution | 1988 |
[The antibacterial effect of ciprofloxacin, ofloxacin and norfloxacin in vitro].
Topics: Bacteria; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin | 1988 |
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Pipemidic Acid; Proteus; Providencia; Urinary Tract Infections | 1988 |
In vitro activities of five new quinolones against 88 genital and neonatal Haemophilus isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Female; Genital Diseases, Female; Genital Diseases, Male; Haemophilus; Haemophilus Infections; Haemophilus influenzae; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1988 |
Bactericidal activity of ciprofloxacin, norfloxacin and ofloxacin in serum and urine after oral administration to healthy volunteers.
Topics: Administration, Oral; Ciprofloxacin; Escherichia coli; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines | 1988 |
[In vitro antibacterial activity of 2 new quinolones: A 56619 (difloxacin) and A 56620. Comparison with pefloxacin, ofloxacin and ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
[Modulation by quinolones of the in vitro proliferative response of splenic cells of the mouse and IL 1 production].
Topics: Animals; Anti-Infective Agents; Cell Division; Cells, Cultured; Ciprofloxacin; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred DBA; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Spleen | 1987 |
[Antibiotics and chemotaxis in agarose. The role of incubation conditions and application to several fluoroquinolones].
Topics: Anti-Infective Agents; Cell Movement; Chemotaxis, Leukocyte; Doxycycline; Humans; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sepharose | 1987 |
Fluoroquinolone derivatives: effects on neutrophil functional tests.
Topics: Anti-Infective Agents; Candida albicans; Chemotaxis, Leukocyte; Ciprofloxacin; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Pefloxacin; Phagocytosis; Staphylococcus aureus | 1987 |
Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice.
Topics: Abscess; Animals; Anti-Bacterial Agents; Autoradiography; Disease Models, Animal; Kinetics; Male; Mice; Nephritis; Norfloxacin; Ofloxacin; Oxazines; Staphylococcal Infections; Staphylococcal Skin Infections | 1986 |
The comparative pharmacokinetics and tissue penetration of four quinolones including intravenously administered enoxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Half-Life; Humans; Kinetics; Male; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Tissue Distribution | 1986 |
Quinolone antimicrobial agents in acute exacerbations of chronic bronchitis.
Topics: Anti-Infective Agents; Bacterial Infections; Bronchitis; Ciprofloxacin; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
[Comparison of in vitro growth-inhibitory activities of ofloxacin, ciprofloxacin and norfloxacin against various species of mycobacteria (comparison of organ concentrations and blood concentrations in mice)].
Topics: Animals; Ciprofloxacin; Drug Resistance, Microbial; Male; Mice; Mycobacterium; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1986 |
[Gyrase inhibitors: unwanted central nervous system effects].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brain Chemistry; Brain Diseases; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Solubility | 1987 |
The comparative pharmacokinetics of five quinolones.
Topics: Administration, Oral; Adult; Ciprofloxacin; Enoxacin; Half-Life; Humans; Infusions, Intravenous; Kinetics; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1986 |
Effects of quinolones on granulocyte function in vitro.
Topics: Anti-Infective Agents; Cell Survival; Ciprofloxacin; Hexosephosphates; Humans; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Phagocytosis | 1986 |
The sensitivity of gram-negative and gram-positive bacteria to ofloxacin.
Topics: Ampicillin; Anti-Bacterial Agents; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperacillin | 1987 |
In-vitro selection of bacteria resistant to the 4-quinolone agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Staphylococcus; Streptococcus | 1987 |
CI-934, a new difluoroquinolone: in vitro antibacterial activity and proposed disk diffusion test interpretive criteria.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Regression Analysis | 1987 |
Comparative in vitro activities of pefloxacin, ofloxacin, enoxacin and ciprofloxacin against 256 clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of ciprofloxacin, ofloxacin and pefloxacin against resistant clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative in vitro activity of amifloxacin and five other fluoroquinolone antimicrobial agents and preliminary criteria for the disk susceptibility test.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
[Therapeutic contribution of the new quinolones].
Topics: Anti-Infective Agents; Bacterial Infections; Biotransformation; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Therapy, Combination; Humans; Kinetics; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Activity of ofloxacin and pefloxacin against Mycobacterium leprae in mice.
Topics: Animals; Drug Evaluation, Preclinical; Leprosy; Mice; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Comparative pharmacokinetics of theophylline following two fluoroquinolones co-administration.
Topics: Adult; Anti-Infective Agents; Drug Interactions; Female; Humans; Kinetics; Male; Norfloxacin; Ofloxacin; Oxazines; Theophylline | 1987 |
The adverse effects of fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones | 1987 |
New synthetic quinolone antibacterial agents and serum concentration of theophylline.
Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline | 1987 |
Susceptibility of urinary isolates of Corynebacterium group D2 to fifteen antimicrobials and acetohydroxamic acid.
Topics: Anti-Bacterial Agents; Bacteriuria; Corynebacterium; Humans; Hydrogen-Ion Concentration; Hydroxamic Acids; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Vancomycin | 1987 |
Polymorphonuclear leucocyte chemotaxis little affected by three quinolones in vitro.
Topics: Anti-Infective Agents; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Neutrophils; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro susceptibility of Mycobacterium fortuitum, Mycobacterium chelonae and Mycobacterium avium against some quinolones.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines | 1987 |
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
Comparative pharmacokinetics of new quinolones.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Enoxacin; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
[Fluoroquinolones].
Topics: Bacteria; Chemical Phenomena; Chemistry; Ciprofloxacin; Enoxacin; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines | 1987 |
Comparative effects of quinolones on human mononuclear leucocyte functions.
Topics: Cell Survival; Ciprofloxacin; Humans; Indomethacin; Interleukin-1; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Monocytes; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
In vitro activity of ciprofloxacin, norfloxacin, and ofloxacin against multi-resistant Enterobacteriaceae.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin | 1987 |
Frequency and expression of mutational resistance to the 4-quinolone antibacterials.
Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1986 |
The in-vitro activity of EN 272, a quinolone-7-carboxylic acid, in comparison with other quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones; Structure-Activity Relationship; Urinary Tract Infections | 1985 |
Ofloxacin: antibacterial activity, induction of resistance and killing curves.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid | 1985 |
Antibacterial activity of ofloxacin and other 4-quinolone derivatives: in-vitro and in-vivo comparison.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Blood Proteins; Drug Resistance, Microbial; Male; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding | 1985 |
In-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Enoxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mutation; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1985 |
[Comparative bacteriologic activity of norfloxacin, ofloxacin and pefloxacin against 320 Gram-negative bacilli resistant and non-resistant to nalidixic acid and cephalosporins].
Topics: Acinetobacter; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas aeruginosa | 1985 |
Comparison of the antibacterial in vitro and in vivo activity of ofloxacin (HOE 280 DL 8280) and nalidixic acid analogues.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Drug Resistance, Microbial; Lactams; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid | 1983 |
Mutational resistance to 4-quinolone antibacterial agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Humans; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Species Specificity | 1984 |
In-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid.
Topics: Bacteria; Bacterial Infections; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1984 |
[In vitro antibacterial activity of balofloxacin (BLFX) against isolates from patients with bacterial enteritis].
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Enteritis; Enterobacteriaceae Infections; Escherichia coli; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Salmonella; Shigella | 1995 |
Topical 0.3% ciprofloxacin, norfloxacin, and ofloxacin in treatment of bacterial keratitis: a new method for comparative evaluation of ocular drug penetration.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromatography, High Pressure Liquid; Ciprofloxacin; Cornea; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Keratitis; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions | 1995 |
Determination of the susceptibility in vitro of 54 isolates of Mycobacterium fortuitum against three fluoroquinolones using two methods.
Topics: Anti-Infective Agents; Ciprofloxacin; Microbial Sensitivity Tests; Mycobacterium; Norfloxacin; Ofloxacin | 1995 |
Tandem scanning confocal microscopic analysis of ciprofloxacin corneal deposits in vivo.
Topics: Administration, Topical; Animals; Calcinosis; Chemical Precipitation; Ciprofloxacin; Cornea; Corneal Diseases; Epithelium; Humans; Hydrogen-Ion Concentration; Male; Microscopy, Confocal; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Rabbits; Random Allocation; Tears; Wound Healing | 1995 |
Function of the SOS process in repair of DNA damage induced by modern 4-quinolones.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; RNA, Bacterial; SOS Response, Genetics | 1993 |
Levofloxacin, an optical isomer of ofloxacin, has attenuated epileptogenic activity in mice and inhibitory potency in GABA receptor binding.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cisterna Magna; GABA Antagonists; In Vitro Techniques; Injections; Isomerism; Levofloxacin; Mice; Mice, Inbred Strains; Norfloxacin; Ofloxacin; Phenylacetates; Protein Binding; Receptors, GABA; Seizures | 1994 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
Sequential acquisition of norfloxacin and ofloxacin resistance by methicillin-resistant and -susceptible Staphylococcus aureus.
Topics: Base Sequence; Humans; Japan; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Ofloxacin; Polymorphism, Restriction Fragment Length; Staphylococcal Infections; Staphylococcus aureus | 1993 |
[Dynamics of fluoroquinolone agents in tear fluid--a comparison of the dynamic in tears of human and rabbit eyes].
Topics: Administration, Oral; Administration, Topical; Adult; Animals; Humans; Male; Norfloxacin; Ofloxacin; Rabbits; Tears | 1994 |
Effects of ciprofloxacin, norfloxacin, and ofloxacin on in vitro adhesion and survival of Pseudomonas aeruginosa AK1 on urinary catheters.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Chromatography, High Pressure Liquid; Ciprofloxacin; Equipment Contamination; Humans; Microscopy, Electron, Scanning; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Spectrophotometry, Ultraviolet; Urinary Catheterization | 1994 |
Dissociation and complexation of fluoroquinolone analogues.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Ferric Compounds; Models, Theoretical; Norfloxacin; Ofloxacin; Spectrophotometry | 1994 |
Interference of ofloxacin with determination of urinary porphyrins.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; False Positive Reactions; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Porphyrins; Spectrometry, Fluorescence | 1994 |
Comparative study of permeability into rat cerebrospinal fluid of the quinolones: dependency on their lipophilicities.
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Injections, Intravenous; Male; Nalidixic Acid; Norfloxacin; Ofloxacin; Rats; Rats, Wistar | 1994 |
Antagonism between bactericidal activities of 4-quinolones and coumarins gives insight into 4-quinolone killing mechanisms.
Topics: Aminocoumarins; Anti-Infective Agents; Ciprofloxacin; Coumarins; DNA Topoisomerases, Type II; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Rifampin | 1994 |
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?
Topics: Biological Transport; Carbon Radioisotopes; Cells, Cultured; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Humans; Intestinal Mucosa; Norfloxacin; Ofloxacin; Pefloxacin; Quinolizines | 1994 |
Simultaneous determination of ofloxacin, norfloxacin and ciprofloxacin in human hair by high-performance liquid chromatography and fluorescence detection.
Topics: Adult; Chromatography, High Pressure Liquid; Ciprofloxacin; Hair; Humans; Middle Aged; Norfloxacin; Ofloxacin; Reproducibility of Results; Spectrometry, Fluorescence; Spectrum Analysis | 1994 |
High prevalence of Neisseria gonorrhoeae strains with reduced susceptibility to fluoroquinolones in Japan.
Topics: Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Serotyping; Urethritis | 1994 |
Mechanistic study of inhibition of levofloxacin absorption by aluminum hydroxide.
Topics: Aluminum Hydroxide; Animals; Buffers; Chemical Phenomena; Chemistry, Physical; Chloroform; Drug Interactions; Enoxacin; Intestinal Absorption; Levofloxacin; Male; Norfloxacin; Ofloxacin; Phosphates; Rats; Rats, Sprague-Dawley | 1993 |
Effectiveness of norfloxacin and ofloxacin for treatment of gonorrhoea and decrease of in vitro susceptibility to quinolones over time in Rwanda.
Topics: Administration, Oral; Adult; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Rwanda; Treatment Outcome | 1993 |
Induction of resistance of Streptococcus pneumoniae to quinolones in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1993 |
In vitro activity of fluoroquinolones against chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum.
Topics: Animals; Chloroquine; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmodium falciparum | 1993 |
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Lung Diseases; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Urinary Tract Infections | 1993 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Ofloxacin, norfloxacin and ceftazidime increase the production of alginate and promote the formation of biofilm of Pseudomonas aeruginosa in vitro.
Topics: Alginates; Anti-Infective Agents; Biofilms; Ceftazidime; Cephalosporins; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa | 1995 |
Modulation of biofilms of Pseudomonas aeruginosa by quinolones.
Topics: Anti-Infective Agents; Bacterial Adhesion; Biofilms; Catheterization; Ciprofloxacin; Glycoproteins; Norfloxacin; Ofloxacin; Pefloxacin; Polysaccharides; Pseudomonas aeruginosa | 1995 |
A comparison of ciprofloxacin, norfloxacin, ofloxacin, azithromycin and cefixime examined by observational cohort studies.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Cefotaxime; Ciprofloxacin; Cohort Studies; Drug Prescriptions; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Pregnancy; Product Surveillance, Postmarketing; Treatment Outcome | 1996 |
Pharmacokinetics of topically applied ciprofloxacin in rabbit tears.
Topics: Animals; Anti-Infective Agents; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Rabbits; Tears | 1996 |
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones | 1996 |
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.
Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones | 1996 |
[Evolution of susceptibilities of Campylobacter jejuni isolated from diarrhoeal cases to fluoroquinolones in Tokyo].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Diarrhea; Drug Resistance, Microbial; Humans; Norfloxacin; Ofloxacin; Tokyo | 1996 |
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells].
Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature | 1996 |
False-positive EMIT II opiates from ofloxacin.
Topics: Anti-Infective Agents; Antibodies; Ciprofloxacin; Cross Reactions; Enzyme Multiplied Immunoassay Technique; False Positive Reactions; Humans; Morphine; Nalidixic Acid; Norfloxacin; Ofloxacin | 1997 |
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation | 1997 |
The role of fluoroquinolones in the promotion of alginate synthesis and antibiotic resistance in Pseudomonas aeruginosa.
Topics: Alginates; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Glucuronic Acid; Hexuronic Acids; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections.
Topics: Anti-Infective Agents; Asparagine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Humans; Incidence; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Serine; Urinary Tract Infections | 1997 |
Penetration of ciprofloxacin, norfloxacin and ofloxacin into the aqueous humours of patients by different topical application modes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Ciprofloxacin; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Prospective Studies | 1997 |
Fluoroquinolone antibiotics block neuromuscular transmission.
Topics: Animals; Anti-Infective Agents; Electrophysiology; Motor Endplate; Neuromuscular Junction; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar; Synaptic Transmission | 1998 |
In vitro susceptibility of multiple drug resistant Salmonella typhimurium to newer fluroquinolone derivatives.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea, Infantile; Drug Resistance, Multiple; Humans; In Vitro Techniques; Infant; Norfloxacin; Ofloxacin; Salmonella Infections; Salmonella typhimurium | 1995 |
Retention behaviour of quinolone derivatives in high-performance liquid chromatography. Effect of pH and evaluation of ionization constants.
Topics: Acetonitriles; Anti-Infective Agents; Chromatography, High Pressure Liquid; Enoxacin; Fleroxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Osmolar Concentration; Potentiometry; Quinolizines; Quinolones; Thermodynamics; Water | 1998 |
Structure and medium-dependent photodecomposition of fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Enoxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Photosensitizing Agents; Quantum Theory; Quinolones; Structure-Activity Relationship | 1998 |
[Clinical and laboratory studies with typhoid fever 178 patients].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Female; Hepatitis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Myocarditis; Norfloxacin; Ofloxacin; Salmonella typhi; Typhoid Fever | 1997 |
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Bacterial Proteins; Biological Transport; Ciprofloxacin; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1999 |
Penetration of ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor using different topical application modes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Bacteria; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Ciprofloxacin; Cornea; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Prospective Studies | 1999 |
Synthesis and methemoglobin toxicity of the amides of 6/7 mono or disubstituted quinolone.
Topics: Amides; Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome-B(5) Reductase; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Methemoglobin; Methemoglobinemia; Norfloxacin; Ofloxacin; Quinolones; Structure-Activity Relationship | 1999 |
Infections caused by Escherichia coli resistant to norfloxacin in hospitalized cirrhotic patients.
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Norfloxacin; Ofloxacin; Time Factors; Treatment Outcome | 1999 |
[The uptake of fluoroquinolone agent drugs by cultured human conjunctival epithelial cells and cultured SIRC rabbit corneal cells].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Conjunctiva; Cornea; Epithelial Cells; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Rabbits | 1999 |
The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Omeprazole; Species Specificity; Staphylococcal Infections; Staphylococcus aureus | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
Novel action of quinolones on osteoclast-like cells.
Topics: Animals; Cells, Cultured; Dinoprostone; Histocytochemistry; Male; Mice; Nalidixic Acid; Norfloxacin; Ofloxacin; Osteoclasts; Quinolones; Spleen; Tumor Necrosis Factor-alpha | 1999 |
Spectroscopic properties of fluoroquinolone antibiotics and nanosecond solvation dynamics in aerosol-OT reverse micelles.
Topics: Anti-Infective Agents; Fluoroquinolones; Micelles; Norfloxacin; Ofloxacin; Photochemistry; Quinolizines; Solvents; Spectrometry, Fluorescence; Spectrophotometry | 2000 |
[Accumulation and efflux of quinolones by clinical isolates of Stenotrophomonas maltophilia].
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Biological Transport, Active; Blotting, Western; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Membrane Potentials; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Stenotrophomonas maltophilia; Uncoupling Agents | 2000 |
Study on three-dimensional fluorescent spectral characteristics of fluoroquinolones in varying media.
Topics: Acids; Anti-Infective Agents; Ciprofloxacin; Dioctyl Sulfosuccinic Acid; Micelles; Norfloxacin; Ofloxacin; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Water | 2000 |
In vitro selection of fluoroquinolone-resistant Neisseria gonorrhoeae harboring alterations in DNA gyrase and topoisomerase IV.
Topics: Anti-Infective Agents; Aspartic Acid; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Glutamic Acid; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Selection, Genetic; Serine | 2000 |
[Antibacterial activity of fosfomycin against the causative bacteria isolated from bacterial enteritis].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Blood; Campylobacter; Electrolytes; Enteritis; Escherichia coli; Escherichia coli O157; Fosfomycin; Humans; Hydrogen-Ion Concentration; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Salmonella; Shigella | 2000 |
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Seasonal variation in fluoroquinolone prescribing.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Utilization Review; England; Humans; Norfloxacin; Ofloxacin; Seasons; Urinary Tract Infections | 1999 |
Fluorescence characteristic study of the ternary complex of fluoroquinolone antibiotics and cobalt (II) with ATP.
Topics: Adenosine Triphosphate; Anti-Infective Agents; Ciprofloxacin; Cobalt; Fluorescence; Molecular Structure; Norfloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2001 |
In vitro activity of levofloxacin against coagulase-positive and -negative staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Staphylococcus | 2001 |
The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans.
Topics: Adult; Aged; Anti-Infective Agents; Candida albicans; Ciprofloxacin; Digestive System; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Urinary Tract Infections | 2001 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Antimicrobial susceptibilities of Campylobacter strains isolated from broilers in the southern part of Japan from 1995 to 1999.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Cecum; Chickens; Drug Resistance, Microbial; Erythromycin; Japan; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Penicillins; Poultry Diseases; Tetracycline | 2001 |
Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate.
Topics: Aged; Anti-Infective Agents; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Postoperative Complications; Prostate; Prostatic Hyperplasia; Urinary Tract Infections | 2001 |
Studies on the uptake and release of fluoroquinolones by disposable contact lenses.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Contact Lenses, Hydrophilic; Disposable Equipment; Drug Delivery Systems; Fluoroquinolones; Norfloxacin; Ofloxacin; Quinolones | 2001 |
Accumulation of five fluoroquinolones by Mycobacterium tuberculosis H37Rv.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolines | 2001 |
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database.
Topics: Adult; Aged; Anti-Infective Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Cohort Studies; Databases, Factual; Drug Monitoring; England; Enoxacin; Family Practice; Female; Humans; Liver Diseases; Male; Middle Aged; Norfloxacin; Ofloxacin; Product Surveillance, Postmarketing; Retrospective Studies; Surveys and Questionnaires; Time Factors | 2001 |
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins | 2001 |
[In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin].
Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Drug Resistance; Drug Resistance, Multiple, Bacterial; Erythromycin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Penicillins; Quinolines; Streptococcal Infections; Streptococcus | 2001 |
Endotoxin release after antibiotic treatment and its potential pathogenetic role in coagulative disorders of patients with gram-negative sepsis.
Topics: Anti-Infective Agents; Blood Coagulation Disorders; Endotoxins; Humans; Norfloxacin; Ofloxacin; Salmonella Infections; Salmonella typhimurium; Shock, Septic | 1991 |
Clinical toxicological aspects of fluoroquinolones.
Topics: Anti-Infective Agents; Bacterial Infections; Cardiovascular Diseases; Central Nervous System Diseases; Ciprofloxacin; Connective Tissue Diseases; Diarrhea; Dizziness; Gastrointestinal Diseases; Headache; Humans; Nausea; Norfloxacin; Ofloxacin; Vomiting | 2002 |
[Comparative in vitro activities of several antimicrobial agents against Helicobacter pylori].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Gastric Mucosa; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Stomach Ulcer | 2002 |
Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Ofloxacin; Quinolones; Solvents | 2003 |
[In vitro fluoroquinolone resistance in ocular bacterial isolates].
Topics: Actinomyces; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Eye; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Norfloxacin; Ofloxacin | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones | 2003 |
[Do tendon lesions occur during quinolone administration?].
Topics: Achilles Tendon; Adult; Age Factors; Anti-Infective Agents; Bronchitis; Ciprofloxacin; Enzyme Inhibitors; Fluoroquinolones; Humans; Incidence; Male; Norfloxacin; Ofloxacin; Risk Factors; Rupture; Time Factors | 2003 |
Corneal and scleral permeability of quinolones--a pharmacokinetics study.
Topics: Administration, Topical; Animals; Aqueous Humor; Cell Membrane Permeability; Cinoxacin; Ciprofloxacin; Conjunctiva; Cornea; Enoxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Rabbits; Sclera; Time Factors; Water | 2003 |
Acquisition of quinolone resistance and point mutation of the gyrA gene in Campylobacter jejuni isolated from broilers and in vitro-induced resistant strains.
Topics: Animals; Base Sequence; Campylobacter jejuni; Chickens; DNA Gyrase; DNA Primers; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Quinolines; Sequence Analysis, DNA | 2004 |
Atomic absorption spectroscopic, conductometric and colorimetric methods for determination of fluoroquinolone antibiotics using ammonium reineckate ion-pair complex formation.
Topics: Absorption; Acetone; Anti-Bacterial Agents; Ciprofloxacin; Colorimetry; Dose-Response Relationship, Drug; Electric Conductivity; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Linear Models; Norfloxacin; Ofloxacin; Quaternary Ammonium Compounds; Quinolones; Salts; Solvents; Spectrophotometry, Atomic; Thiocyanates | 2004 |
[Study on the molecular mechanism of quinolone resistance in Shigellae spp].
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pipemidic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Quinolones; Shigella | 2004 |
Diabetes mellitus in itself is not a risk factor for antibiotic resistance in Escherichia coli isolated from patients with bacteriuria.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Bacteriuria; Ciprofloxacin; Diabetes Complications; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Middle Aged; Nitrofurantoin; Norfloxacin; Ofloxacin; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Bacterial Agents; Arrhythmias, Cardiac; Case-Control Studies; Ciprofloxacin; Clarithromycin; Cohort Studies; Community Health Planning; Databases, Factual; Drug Monitoring; Erythromycin; Humans; Italy; Levofloxacin; Miocamycin; Norfloxacin; Ofloxacin; Pharmacoepidemiology; Risk Factors | 2005 |
Spectrophotometric determination of some fluoroquinolone antibacterials by binary complex formation with xanthene dyes.
Topics: Anti-Infective Agents; Ciprofloxacin; Eosine Yellowish-(YS); Levofloxacin; Merbromin; Norfloxacin; Ofloxacin; Spectrophotometry, Ultraviolet; Tablets | 2004 |
A comparison of effects of fluoroquinolones on fracture healing (an experimental study in rats).
Topics: Animals; Ciprofloxacin; Femoral Fractures; Fluoroquinolones; Fracture Healing; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar | 2005 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Sensitivity and Specificity; Spectrometry, Fluorescence | 2005 |
Interactions between 4-quinolone antibacterials and multivalent metal ions.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Metals; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1989 |
Enhancement of antibacterial activity of norfloxacin and ofloxacin in vitro by serum and experimental pleural exudates.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Escherichia coli; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pleural Effusion; Rats; Rats, Wistar | 1989 |
Inhibitory effect of several fluoroquinolones on hepatic microsomal cytochrome P-450 1A activities in dogs.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Cytochrome P-450 CYP1A1; Dogs; Drug Interactions; Enrofloxacin; Fluoroquinolones; Male; Microsomes, Liver; Norfloxacin; Ofloxacin | 2005 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Cell Line; Ciprofloxacin; Dogs; Female; Fluoroquinolones; Lactation; Male; Mice; Mice, Knockout; Milk; Neoplasm Proteins; Norfloxacin; Ofloxacin; Transfection | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution | 2006 |
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].
Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood | 2006 |
Effect of ofloxacin on theophylline pharmacokinetics at clinical dosage in dogs.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Dogs; Drug Interactions; Female; Half-Life; Injections, Intravenous; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Protein Binding; Theophylline; Vasodilator Agents | 2006 |
Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Amoxicillin; Anti-Bacterial Agents; China; Chloramphenicol; Chromatography, High Pressure Liquid; Climate; Erythromycin; Hong Kong; Macrolides; Norfloxacin; Ofloxacin; Quinolones; Rivers; Seasons; Seawater; Spectrometry, Mass, Electrospray Ionization; Sulfanilamides; Time Factors; Waste Management; Water Pollutants, Chemical | 2007 |
Computational and experimental approaches for assessing the interactions between the model calycin beta-lactoglobulin and two antibacterial fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Binding Sites; Cattle; Computational Biology; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Levofloxacin; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Norfloxacin; Ofloxacin; Thermodynamics | 2006 |
Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.
Topics: Absorption; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Iron Compounds; Kinetics; Minerals; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction | 2007 |
Solution studies on binary and ternary complexes of copper(II) with some fluoroquinolones and 1,10-phenanthroline: Antimicrobial activity of ternary metalloantibiotics.
Topics: Anti-Bacterial Agents; Copper; Drug Design; Drug Resistance, Microbial; Drug Stability; Ligands; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Phenanthrolines; Potentiometry; Spectrophotometry, Ultraviolet | 2007 |
Determination of ofloxacin, norfloxacin, and ciprofloxacin in sewage by selective solid-phase extraction, liquid chromatography with fluorescence detection, and liquid chromatography--tandem mass spectrometry.
Topics: Chromatography, Liquid; Ciprofloxacin; Fluorescence; Molecular Structure; Norfloxacin; Ofloxacin; Reproducibility of Results; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2007 |
Development of a monoclonal antibody-based broad-specificity ELISA for fluoroquinolone antibiotics in foods and molecular modeling studies of cross-reactive compounds.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibody Specificity; Ciprofloxacin; Enrofloxacin; Enzyme-Linked Immunosorbent Assay; Fluoroquinolones; Food Contamination; Inhibitory Concentration 50; Norfloxacin; Ofloxacin; Quantitative Structure-Activity Relationship; Sensitivity and Specificity | 2007 |
Resolution of ofloxacin-ciprofloxacin and ofloxacin-norfloxacin binary mixtures by flow-injection chemiluminescence in combination with partial least squares multivariate calibration.
Topics: Anti-Infective Agents; Cerium; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Combinations; Flow Injection Analysis; Least-Squares Analysis; Luminescent Measurements; Multivariate Analysis; Norfloxacin; Ofloxacin; Organometallic Compounds; Sulfuric Acids | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Determination of ulifloxacin by terbium-sensitized fluorescence with second-order scattering and its applications.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Humans; Indicators and Reagents; Luminescence; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Scattering, Radiation; Spectrometry, Fluorescence; Terbium | 2007 |
Determination of levofloxacin and norfloxacin by capillary electrophoresis with electrochemiluminescence detection and applications in human urine.
Topics: Electrophoresis, Capillary; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Levofloxacin; Luminescent Measurements; Male; Norfloxacin; Ofloxacin; Osmolar Concentration; Sodium Hydroxide; Solvents | 2008 |
Comparison of solid-phase sorbents for the determination of fluoroquinolone antibiotics in wastewater.
Topics: Adsorption; Anti-Bacterial Agents; Cation Exchange Resins; Chromatography, High Pressure Liquid; Ciprofloxacin; Edetic Acid; Enrofloxacin; Fluoroquinolones; Hydrophobic and Hydrophilic Interactions; Norfloxacin; Ofloxacin; Polymers; Reproducibility of Results; Sensitivity and Specificity; Sewage; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2008 |
Study of fluorescence characteristics of the charge-transfer reaction of quinolone agents with bromanil.
Topics: Anti-Bacterial Agents; Benzoquinones; Catalysis; Ciprofloxacin; Electrons; Energy Transfer; Models, Biological; Norfloxacin; Ofloxacin; Osmolar Concentration; Quinolones; Solvents; Spectrometry, Fluorescence; Technology, Pharmaceutical; Temperature; Time Factors | 2009 |
Mechanisms accounting for fluoroquinolone resistance in Escherichia coli clinical isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin | 2009 |
Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.
Topics: Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; United States | 2009 |
Determination of quinolone antibiotics in urine by capillary electrophoresis with chemiluminescence detection.
Topics: Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Humans; Luminescent Measurements; Molecular Structure; Norfloxacin; Ofloxacin; Quinolones; Sensitivity and Specificity; Solvents | 2008 |
Sequential determination of norfloxaxin and levofloxacin in the presence of other fluorquinolones using synchronous scanning room-temperature phosphorimetry and Th (IV) as the selective signal inducer.
Topics: Animals; Anti-Infective Agents, Urinary; Humans; Levofloxacin; Luminescent Measurements; Norfloxacin; Ofloxacin; Thallium | 2009 |
Fluoroquinolone-resistant Brucella melitensis mutants obtained in vitro.
Topics: Anti-Bacterial Agents; Aza Compounds; Brucella melitensis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Norfloxacin; Ofloxacin; Quinolines; Sequence Analysis, DNA | 2009 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures | 2009 |
[Multi-residue determination of 11 quinolones in chicken muscle by high performance liquid chromatography with fluorescence detection].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluorescence; Norfloxacin; Ofloxacin; Poultry Products; Quinolones | 2009 |
Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Survival; Cells, Cultured; Ciprofloxacin; Electric Impedance; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines | 2010 |
Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA.
Topics: DNA; Drug Interactions; Drug Synergism; Fluoroquinolones; Norfloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2009 |
[Simultaneous analysis of 7 fluoroquinolone residues in chicken muscle by ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluoroquinolones; Food Contamination; Meat; Norfloxacin; Ofloxacin; Poultry; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Competitive sorption and desorption behavior for three fluoroquinolone antibiotics in a wastewater treatment wetland soil.
Topics: Absorption; Adsorption; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Kinetics; Norfloxacin; Ofloxacin; Soil; Soil Pollutants; Waste Disposal, Fluid; Wetlands | 2010 |
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater.
Topics: Chemical Fractionation; Chemistry, Pharmaceutical; Chromatography, Liquid; Emulsions; Enrofloxacin; Ethane; Fluoroquinolones; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Methanol; Norfloxacin; Ofloxacin; Ultrasonics; Water Pollutants, Chemical; Water Purification | 2011 |
Chemiluminescence determination of fluoroquinolones using Fenton system in the presence of terbium(iii) ions.
Topics: Ciprofloxacin; Fluoroquinolones; Hydrogen Peroxide; Ions; Iron; Luminescent Measurements; Norfloxacin; Ofloxacin; Pharmaceutical Preparations; Spectrometry, Fluorescence; Terbium | 2011 |
Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: comparison of biomechanical and histopathological effects on Achilles tendon in rats.
Topics: Achilles Tendon; Administration, Oral; Animals; Anti-Bacterial Agents; Ciprofloxacin; Elastic Modulus; Elasticity; Fluoroquinolones; Male; Norfloxacin; Ofloxacin; Pefloxacin; Rats; Rats, Wistar; Tensile Strength | 2011 |
Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS.
Topics: Amoxicillin; Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Erythromycin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Oxolinic Acid; Reproducibility of Results; Rivers; Solid Phase Extraction; Sulfamethoxazole; Tandem Mass Spectrometry; Tetracycline; Trimethoprim; Tylosin; Vancomycin; Water Pollutants, Chemical | 2011 |
Two fluoroalcohols as components of basic buffers for liquid chromatography electrospray ionization mass spectrometric determination of antibiotic residues.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Drug Residues; Lactuca; Mass Spectrometry; Norfloxacin; Ofloxacin; Propanols; Spectrometry, Mass, Electrospray Ionization; Sulfadimethoxine; Sulfamethoxazole | 2011 |
In vitro comparison of the cytotoxic effects of clinically available ophthalmic solutions of fluoroquinolones on human keratocytes.
Topics: Anti-Bacterial Agents; Aza Compounds; Benzalkonium Compounds; Cells, Cultured; Corneal Keratocytes; Culture Media; Fluoroquinolones; Gatifloxacin; Humans; L-Lactate Dehydrogenase; Microscopy, Phase-Contrast; Moxifloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines | 2011 |
Grafting of norfloxacin imprinted polymeric membranes on silica surface for the selective solid-phase extraction of fluoroquinolones in fish samples.
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Fishes; Limit of Detection; Membranes, Artificial; Methacrylates; Molecular Imprinting; Norfloxacin; Ofloxacin; Polymers; Porosity; Silanes; Silica Gel; Solid Phase Extraction; Solvents; Vinyl Compounds | 2012 |
Molecular epidemiology of fluoroquinolone resistance in invasive clinical isolates of Streptococcus pneumoniae in Seville.
Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Fluoroquinolones; Humans; Infant; Job Syndrome; Levofloxacin; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pneumococcal Infections; Reserpine; Serotyping; Spain; Streptococcus pneumoniae | 2012 |
Aluminium sensitized spectrofluorimetric determination of fluoroquinolones in milk samples coupled with salting-out assisted liquid-liquid ultrasonic extraction.
Topics: Acetonitriles; Aluminum; Ammonium Sulfate; Animals; Cattle; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Limit of Detection; Liquid-Liquid Extraction; Milk; Norfloxacin; Ofloxacin; Solutions; Spectrometry, Fluorescence; Temperature; Ultrasonics; Water | 2012 |
In vitro assessment of the cytotoxicity of six topical antibiotics to four cultured ocular surface cell lines.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cefmenoxime; Cell Line; Cell Survival; Conjunctiva; Cornea; Dibekacin; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines; Rabbits | 2012 |
Adsorption of ofloxacin and norfloxacin on carbon nanotubes: hydrophobicity- and structure-controlled process.
Topics: Adsorption; Anti-Bacterial Agents; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Nanotubes, Carbon; Norfloxacin; Ofloxacin; Water Pollutants, Chemical; Water Purification | 2012 |
Different types of copper complexes with the quinolone antimicrobial drugs ofloxacin and norfloxacin: structure, DNA- and albumin-binding.
Topics: Albumins; Animals; Anti-Bacterial Agents; Cattle; Coordination Complexes; Copper; Crystallography, X-Ray; DNA; Ethidium; Humans; Intercalating Agents; Models, Molecular; Norfloxacin; Ofloxacin; Protein Binding; Serum Albumin; Spectrometry, Fluorescence | 2012 |
Direct photochemistry of three fluoroquinolone antibacterials: norfloxacin, ofloxacin, and enrofloxacin.
Topics: Anti-Bacterial Agents; Enrofloxacin; Fluoroquinolones; Molecular Structure; Norfloxacin; Ofloxacin; Photochemical Processes; Photolysis; Water Pollutants, Chemical | 2013 |
Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Microscopy, Confocal; Microscopy, Electron, Scanning; Norfloxacin; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes; Virulence | 2013 |
Phase distribution and removal of pharmaceuticals and personal care products during anaerobic sludge digestion.
Topics: Anti-Infective Agents; Carbamazepine; Carbanilides; Environmental Monitoring; Household Products; Hydrogen-Ion Concentration; Japan; Kinetics; Norfloxacin; Ofloxacin; Pharmaceutical Preparations; Sewage; Triclosan; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2013 |
Biodegradation of ofloxacin, norfloxacin, and ciprofloxacin as single and mixed substrates by Labrys portucalensis F11.
Topics: Alphaproteobacteria; Anti-Bacterial Agents; Biotransformation; Carbon; Chromatography, Liquid; Ciprofloxacin; Culture Media; Environmental Pollutants; Fluorides; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Norfloxacin; Ofloxacin | 2014 |
Performance of aerobic granular sludge in a sequencing batch bioreactor exposed to ofloxacin, norfloxacin and ciprofloxacin.
Topics: Aerobiosis; Bacteria; Batch Cell Culture Techniques; Biological Oxygen Demand Analysis; Bioreactors; Ciprofloxacin; Cluster Analysis; Denaturing Gradient Gel Electrophoresis; Nitrogen; Norfloxacin; Ofloxacin; Phosphates; Phylogeny; RNA, Ribosomal, 16S; Sewage | 2014 |
Sorption and solubility of ofloxacin and norfloxacin in water-methanol cosolvent.
Topics: Adsorption; Anti-Bacterial Agents; Hydrogen Bonding; Methanol; Nanotubes, Carbon; Norfloxacin; Ofloxacin; Solubility; Solvents; Water; Water Pollutants, Chemical | 2014 |
Degradation of fluoroquinolone antibiotics and identification of metabolites/transformation products by liquid chromatography-tandem mass spectrometry.
Topics: Anti-Bacterial Agents; Aza Compounds; Biotransformation; Chromatography, Liquid; Ciprofloxacin; Fluoroquinolones; Moxifloxacin; Norfloxacin; Ofloxacin; Photolysis; Quinolines; Tandem Mass Spectrometry | 2014 |
[Simultaneous determination of clopidol, sulfonamide and quinolone residues in chickens by ultra performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Clopidol; Drug Residues; Enrofloxacin; Fluoroquinolones; Food Contamination; Hexanes; Meat; Norfloxacin; Ofloxacin; Quinolones; Sulfanilamide; Sulfanilamides; Sulfonamides; Tandem Mass Spectrometry | 2013 |
Biotransformation of fluoroquinolone antibiotics by ligninolytic fungi--Metabolites, enzymes and residual antibacterial activity.
Topics: Anti-Bacterial Agents; Biodegradation, Environmental; Biotransformation; Fluoroquinolones; Mass Spectrometry; Norfloxacin; Ofloxacin; Peroxidases; Pleurotus; Polyporales; Trametes | 2015 |
[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Cities; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Soil; Soil Pollutants | 2014 |
Contribution of coated humic acids calculated through their surface coverage on nano iron oxides for ofloxacin and norfloxacin sorption.
Topics: Adsorption; Anti-Bacterial Agents; Ferric Compounds; Humic Substances; Minerals; Norfloxacin; Ofloxacin | 2015 |
[Determination of 25 quinolones in cosmetics by liquid chromatography-tandem mass spectrometry].
Topics: Chromatography, Liquid; Ciprofloxacin; Cosmetics; Drug Residues; Enrofloxacin; Fluoroquinolones; Hexanes; Norfloxacin; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Simultaneous determination of fluoroquinolones in environmental water by liquid chromatography-tandem mass spectrometry with direct injection: A green approach.
Topics: Anti-Bacterial Agents; Brazil; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Fresh Water; Gemifloxacin; Green Chemistry Technology; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2015 |
The occurrence and removal of selected fluoroquinolones in urban drinking water treatment plants.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; China; Ciprofloxacin; Drinking Water; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Norfloxacin; Ofloxacin; Water Pollutants, Chemical; Water Purification | 2015 |
Impacts of urbanization on the prevalence of antibiotic-resistant Escherichia coli in the Chaophraya River and its tributaries.
Topics: Amoxicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Rivers; Tetracycline; Thailand; Urbanization; Water Microbiology | 2016 |
Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology.
Topics: Anti-Bacterial Agents; China; Cities; Erythromycin; Norfloxacin; Ofloxacin; Trimethoprim; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2016 |
[Distribution Characteristics of Fluoroquinolones Antibiotics in Surface Water and Groundwater from Typical Areas in A City].
Topics: Anti-Bacterial Agents; Cities; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Groundwater; Norfloxacin; Ofloxacin; Rivers; Sewage; Water; Water Pollutants, Chemical | 2015 |
Adsorption mechanism of different organic chemicals on fluorinated carbon nanotubes.
Topics: Adsorption; Benzhydryl Compounds; Halogenation; Nanotubes, Carbon; Norfloxacin; Ofloxacin; Phenanthrenes; Phenols; Polytetrafluoroethylene; Sulfamethoxazole; Thermodynamics | 2016 |
Electrochemical oxidation of fluoroquinolone antibiotics: Mechanism, residual antibacterial activity and toxicity change.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin | 2016 |
Risk assessment of three fluoroquinolone antibiotics in the groundwater recharge system.
Topics: Adsorption; Anti-Bacterial Agents; Beijing; China; Enrofloxacin; Environmental Restoration and Remediation; Fluoroquinolones; Groundwater; Norfloxacin; Ofloxacin; Risk Assessment; Soil; Soil Pollutants; Water; Water Pollutants, Chemical | 2016 |
[Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis].
Topics: Adsorption; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Norfloxacin; Ofloxacin; Sewage; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
An automated magnetic dispersive micro-solid phase extraction in a fluidized reactor for the determination of fluoroquinolones in baby food samples.
Topics: Animals; Anti-Bacterial Agents; Cattle; Chickens; Chromatography, High Pressure Liquid; Equipment Design; Fleroxacin; Flow Injection Analysis; Fluoroquinolones; Food Contamination; Humans; Infant; Infant Food; Limit of Detection; Magnetics; Meat; Norfloxacin; Ofloxacin; Solid Phase Microextraction; Turkey | 2018 |
Variable-valence metals catalyzed solid NaBiO
Topics: Bismuth; Catalysis; Ciprofloxacin; Metals; Nanostructures; Norfloxacin; Ofloxacin; Oxidation-Reduction; Oxidative Stress; Oxygen; Sodium; X-Ray Diffraction | 2018 |
[Effect of Fluoroquinolones on Performance and Microbial Community of a Vertical Flow Constructed Wetland].
Topics: Ammonia; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteobacteria; Water Pollutants, Chemical; Wetlands | 2018 |
Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Case-Control Studies; Ciprofloxacin; Female; Fluoroquinolones; Humans; Incidence; Levofloxacin; Male; Middle Aged; Moxifloxacin; Norfloxacin; Ofloxacin; Peripheral Nervous System Diseases; Risk Factors; Sex Factors; United Kingdom | 2019 |
Molecular Modification of Fluoroquinolone-Biodegrading Enzymes Based on Molecular Docking and Homology Modelling.
Topics: Amino Acids; Anti-Bacterial Agents; Binding Sites; Biodegradation, Environmental; Ciprofloxacin; Models, Molecular; Norfloxacin; Ofloxacin | 2019 |
Development of quinolone resistance and prevalence of different virulence genes among Shigella flexneri and Shigella dysenteriae in environmental water samples.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; India; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmids; Prevalence; Quinolones; Shigella dysenteriae; Shigella flexneri; Virulence | 2020 |
Antibiotic use in chicken farms in northwestern China.
Topics: Adult; Animals; Anti-Bacterial Agents; Ceftriaxone; Chickens; China; Cross-Sectional Studies; Drug Misuse; Farms; Female; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Logistic Models; Male; Middle Aged; Norfloxacin; Ofloxacin; One Health; Oxytetracycline; Socioeconomic Factors; Surveys and Questionnaires; Young Adult | 2020 |
Occurrence, sources and risk assessment of fluoroquinolones in dumpsite soil and sewage sludge from Chennai, India.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Cities; Environmental Monitoring; India; Norfloxacin; Ofloxacin; Risk Assessment; Sewage; Soil Pollutants; Waste Disposal Facilities; Water Pollutants, Chemical | 2020 |
The influence mechanism of the molecular structure on the peak current and peak potential in electrochemical detection of typical quinolone antibiotics.
Topics: Anti-Bacterial Agents; Catalysis; Electrochemical Techniques; Enoxacin; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction; Quinolones; Water; Water Pollutants, Chemical | 2021 |
A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Adverse Drug Reaction Reporting Systems; Arthralgia; Ciprofloxacin; Connective Tissue Diseases; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Musculoskeletal Diseases; Myalgia; Norfloxacin; Ofloxacin; Pain; Risk Factors; Tendinopathy; Tendons; Young Adult | 2021 |
Spatial distribution and risk assessment of certain antibiotics in 51 urban wastewater treatment plants in the transition zone between North and South China.
Topics: Anti-Bacterial Agents; China; Environmental Monitoring; Norfloxacin; Ofloxacin; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2022 |
Efficient with low-cost removal and adsorption mechanisms of norfloxacin, ciprofloxacin and ofloxacin on modified thermal kaolin: experimental and theoretical studies.
Topics: Adsorption; Ciprofloxacin; Humans; Kaolin; Kinetics; Models, Theoretical; Norfloxacin; Ofloxacin; Water Pollutants, Chemical | 2022 |
Antibiotics in wastewater of Guangdong, China: distribution patterns, and their environmental risk due to incomplete removal.
Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; China; Ecosystem; Environmental Monitoring; Humans; Middle Aged; Norfloxacin; Ofloxacin; Sulfamethazine; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Young Adult | 2022 |
The variations of antibiotics and antibiotic resistance genes in two subtropical large river basins of south China: Anthropogenic impacts and environmental risks.
Topics: Anthropogenic Effects; Anti-Bacterial Agents; China; Chlortetracycline; Drug Resistance, Microbial; Ecosystem; Enrofloxacin; Genes, Bacterial; Norfloxacin; Ofloxacin; Oxytetracycline; Rivers; RNA, Ribosomal, 16S; Sulfamethoxazole; Sulfonamides; Water | 2022 |
Contamination, transport, and ecological risks of pharmaceuticals and personal care products in a large irrigation region.
Topics: Caffeine; China; Cosmetics; Ecosystem; Environmental Monitoring; Erythromycin; Humans; Norfloxacin; Ofloxacin; Pharmaceutical Preparations; Risk Assessment; Sulfamethoxazole; Water Pollutants, Chemical | 2022 |
Antibiotics and antimycotics in waste water treatment plants: Concentrations, removal efficiency, spatial and temporal variations, prediction, and ecological risk assessment.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Clotrimazole; Environmental Monitoring; Moxifloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Risk Assessment; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2022 |
Reproductive toxicities of ofloxacin and norfloxacin on Caenorhabditis elegans with multi-generational oscillatory effects and trans-generational residual influences.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Cholesterol; Fluoroquinolones; Male; Norfloxacin; Ofloxacin; Progesterone; Reproduction; Semen; Testosterone; Vitellogenins | 2022 |
Techniques for remediation of pharmaceutical pollutants using metal organic framework - Review on toxicology, applications, and mechanism.
Topics: Anti-Bacterial Agents; Carbon Fiber; COVID-19; Environmental Pollutants; Humans; Metal-Organic Frameworks; Norfloxacin; Ofloxacin; Ozone; Wastewater; Xenobiotics | 2022 |
A high-precision prediction for spatiotemporal distribution and risk assessment of antibiotics in an urban watershed using a hydrodynamic model.
Topics: Anti-Bacterial Agents; China; Enrofloxacin; Environmental Monitoring; Erythromycin; Humans; Hydrodynamics; Manure; Norfloxacin; Ofloxacin; Risk Assessment; Rivers; Roxithromycin; Sewage; Sulfamethoxazole; Water Pollutants, Chemical | 2022 |
A NiCoT family metal transporter of
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cobalt; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Ethambutol; Gentamicins; Isoleucine; Isoniazid; Kanamycin; Leucine; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Neomycin; Nickel; Norfloxacin; Ofloxacin | 2022 |
Fluorescent strip sensor for rapid and ultrasensitive determination of fluoroquinolones in fish and milk.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Humans; Milk; Norfloxacin; Ofloxacin; Pefloxacin | 2023 |
In Vitro Inhibitory Effects and Bioinformatic Analysis of Norfloxacin and Ofloxacin on Piroplasm.
Topics: Animals; Babesia; Babesiosis; Cattle; Horse Diseases; Horses; Luteolin; Norfloxacin; Ofloxacin; Theileria; Theileriasis | 2023 |
Spatial and temporal distribution characteristics of antibiotics and heavy metals in the Yitong River basin and ecological risk assessment.
Topics: Adult; Anti-Bacterial Agents; Cadmium; Child; China; Environmental Monitoring; Environmental Pollutants; Geologic Sediments; Humans; Metals, Heavy; Norfloxacin; Ofloxacin; Risk Assessment; Rivers; Water Pollutants, Chemical | 2023 |
Photo-transformation of acetaminophen sensitized by fluoroquinolones in the presence of bromide.
Topics: Acetaminophen; Bromides; Bromine; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Water Pollutants, Chemical | 2023 |
Field measures of strengthen plant-microbial remediation of PAHs-FQs compound pollution.
Topics: Ciprofloxacin; Enrofloxacin; Fluorenes; Molecular Docking Simulation; Norfloxacin; Ofloxacin; Peroxidases; Polycyclic Aromatic Hydrocarbons | 2023 |
A luminous strategy for the recognition of toxic antibiotics in water via efficient energy transfer.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Energy Transfer; Fluoroquinolones; India; Metal-Organic Frameworks; Norfloxacin; Ofloxacin; Water | 2023 |
Photodegradation for different dissociated species of norfloxacin and ofloxacin in water ice under solar irradiation.
Topics: Anti-Bacterial Agents; Cations; Fluoroquinolones; Ice; Norfloxacin; Ofloxacin; Photolysis; Water Pollutants, Chemical | 2024 |
An optimized electro-fenton pretreatment for the degradation and mineralization of a mixture of ofloxacin, norfloxacin, and ciprofloxacin.
Topics: Carboxylic Acids; Ciprofloxacin; Electrodes; Fluoroquinolones; Hydrogen Peroxide; Norfloxacin; Ofloxacin; Oxidation-Reduction; Water Pollutants, Chemical | 2023 |
Abatement of antibiotics and resistance genes during catalytic ozonation enhanced sludge dewatering process: Synchronized in volume and hazardousness reduction.
Topics: Anti-Bacterial Agents; Bacteria; Genes, Bacterial; Norfloxacin; Ofloxacin; Oxytetracycline; Ozone; Sewage; Tetracycline | 2024 |