ofloxacin and nalidixic acid

ofloxacin has been researched along with nalidixic acid in 146 studies

Research

Studies (146)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (35.62)	18.7374
1990's	29 (19.86)	18.2507
2000's	41 (28.08)	29.6817
2010's	21 (14.38)	24.3611
2020's	3 (2.05)	2.80

Authors

Authors	Studies
Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M	1
Domagala, JM; Heifetz, CL; Mich, TF; Nichols, JB	1
Altom, J; Barrett, JF; Fernandez, J; Fraga-Spano, SA; Hilliard, J; Ohemeng, K; Weinder-Wells, MA	1
Blyn, LB; Jefferson, EA; Miyaji, A; Osgood, SA; Risen, LM; Swayze, EE	1
Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W	1
Cattoir, V; Mazel, D; Nordmann, P; Poirel, L; Soussy, CJ	1
Cattoir, V; Nordmann, P; Poirel, L	2
Acosta, CJ; Agtini, M; Albert, MJ; Anh, DD; Arjyal, A; Basnyat, B; Bhattacharya, SK; Bhutta, ZA; Campbell, JI; Canh, DG; Chau, TT; Chinh, NT; Clemens, JD; Diep, TS; Dolecek, C; Dong, B; Dougan, G; Dutta, S; Farrar, J; Galindo, CM; Hien, TT; Honghui, Y; La, TT; Naheed, A; Newton, PN; Nga, TT; Ochiai, RL; Page, AL; Parry, CM; Phetsouvanh, R; Phuong, LT; Rang, NN; Schultsz, C; Tuan, PQ; Van Be Bay, P; Van Minh Hoang, N; Van Vinh Chau, N; Vinh, H; von Seidlein, L; Wain, J	1
Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S	1
Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Mayer, C	1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L	1
Cattoir, V; Espinal, P; Nordmann, P; Poirel, L; Silva-Sanchez, J	1
Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW	1
Aarestrup, FM; Cavaco, LM; Hasman, H; Xia, S	1
Dionisi, AM; Lucarelli, C; Luzzi, I; Owczarek, S; Villa, L	1
Caddick, JM; Gunell, M; Hakanen, AJ; Huovinen, P; Jalava, J; Kotilainen, P; Lilly, AJ; Piddock, LJ; Siitonen, A; Webber, MA	1
Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A	1
Girlich, D; Nordmann, P; Poirel, L	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A	1
Blango, MG; Mulvey, MA	1
Ahn, JH; Bae, IK; Lee, JE; Lee, JJ; Lee, SH; Park, I; Park, KS; Sun, HI; Woo, GJ	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Fallarero, A; Hanski, L; Isojärvi, J; Karhu, E; Vuorela, P	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Alonso-Rodriguez, N; Briffotaux, J; Buchieri, MV; Cimino, M; Coulibaly, S; Dallemagne, P; Gicquel, B; Lecoutey, C; Mornico, D; Ouattara, M; Rochais, C	1
Chyrek-Borowska, S; Michalska, I; Siergiejko, Z; Szymański, W	1
Rahal, K	1
Chelfi, A; Liassine, N; Rahal, K	1
Hoshino, K; Saiki, A; Sawai, T; Yamaguchi, A	1
Carret, G; Flandrois, JP; Lobry, JR	1
Cullmann, W; Dechène, M; Leying, H	1
Carbon, C; Delval, C	1
Baykal, M; Hasçelik, G	1
Duval, J; Le Van Thoi, J; Soussy, CJ	1
Lewin, CS; Smith, JT	1
Kato, H; Nagata, O; Nakamura, M; Okezaki, E; Terasaki, T; Tsuji, A	1
Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC	1
Rehavi, M; Rubinstein, E; Segev, S	1
Santos Ferreira, M; Vital, J	1
Auckenthaler, R; Michéa-Hamzehpour, M; Pechère, JC	1
Avesani, V; Delmee, M	1
Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL	2
Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH	1
Baltch, AL; Bassey, CM; Smith, RP	1
Barry, AL; Jones, RN; Thornsberry, C	1
Grimm, H	1
Forth, W	1
Høiby, N	1
Allocati, N; Oliva, B; Renzini, G; Scazzocchio, F; Schippa, S; Selan, L	1
Cellini, L; Oliva, B; Renzini, G; Scazzocchio, F; Schippa, S; Selan, L	1
Acar, S; Ceyhan, M; Korten, V; Mert, A; Ovünç, K; Ulaş, T	1
Baldinelli, L; De Santis, S; De Simone, C; Ferrazzi, M; Pugnaloni, L; Sorice, F	1
Kubesch, P; Tümmler, B; Wehsling, M	1
Andrews, JM; Ashby, JP; Wise, R	1
Kresken, M; Wiedemann, B	1
Baars, B; Cullmann, W; Opferkuch, W; Stieglitz, M	1
Forsgren, A	1
Butzler, JP; Coignau, H; De Mol, P; Ghysels, G; Goossens, H; Grados, O; Innocent, H; Levy, J	1
Bailey, J; Heppleston, C; Richmond, S	1
Dabernat, H; Delmas, C; Lareng, MB	1
Daguet, GL; Delisle-Mizon, F; Lesage, D; Vergez, P	1
Bergogne-Berezin, E; Joly-Guillou, ML	1
Bryskier, A; Devos, J; Dubreuil, L; Romond, C	1
Golier, J; Langsádl, L; Menkyna, R; Silan, L	1
Kato, M; Onodera, T	1
Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L	1
Guenounou, M; Kodari, E; Momrikof, V; Ronco, E; Vacheron, F	1
Walker, RC; Wright, AJ	1
Fernández-Roblas, R; Méndez, B; Soriano, F; Torres, A	1
Caccamo, F; Nicoletti, G; Nicolosi, VM; Speciale, A; Stefani, S	1
Wolff, M	1
Carlstedt-Duke, B; Høverstad, T; Lingaas, E; Midtvedt, T; Norin, KE; Saxerholt, H; Steinbakk, M	1
Acar, JF; Courvalin, P; Denis, F; Duval, J; Kitzis, MD; Le Van Thoi, J; Malbruny, B; Morel, C; Mounier, M; Soussy, CJ	1
Smith, JT	3
Neu, HC	1
Bryskier, A; Husson, MO; Izard, D; Leclerc, H	1
Bryskier, A; Chantot, JF	1
Bryskier, A; Croize, J; Le Noc, P; Robert, J	1
Klesel, N; Limbert, M; Seibert, G	1
Bauernfeind, A; Ullmann, U	1
Meier-Ewert, H; Millott, G; Weil, G	1
Howard, BM; Pinney, RJ; Smith, JT	2
Mancy, C; Plaisance, JJ; Weber, P	1
Domarle, O; Hayem, G; Pocidalo, JJ; Thuong-Guyot, M	1
Mamet, R; Schoenfeld, N	1
Ichikawa, N; Iwamoto, K; Naora, K	1
Carret, G; Flandrois, JP; Guerillot, F	1
Auckenthaler, R; Peyret, M; Rohner, P	1
Amyes, SG; Brown, JC; Jesudason, MV; Shanahan, PM; Thomson, CJ	1
Conrad, S; Kaifel, K; Kern, WV; Klotz, G; Marre, R; Oethinger, M	1
Dai, J; Meatherall, R	1
Klecak, G; Urbach, F; Urwyler, H	1
Forbes, PD; Mäkinen, M; Stenbäck, F	1
Colston, MJ; Davis, EO; Movahedzadeh, F	1
Deguchi, T; Kawada, Y; Kawamura, T; Nakano, M; Nishino, Y; Ozeki, S; Yasuda, M	1
Sanders, CC; Thomson, KS	1
Farooqui, BJ; Nizami, SQ	1
Maskell, JP; Sefton, AM; Williams, JD	1
Akagi, M; Fukuishi, N; Kanoh, R; Matsui, N	1
Chinh, NT; Diep, TS; Farrar, JJ; Ha, HD; Ly, NT; Parry, CM; Thong, MX; Wain, J; White, NJ	1
Chuma, T; Ikeda, T; Maeda, T; Niwa, H; Okamoto, K	1
Calvo, A; García, R; Gómez-Lus, ML; Leturia, A; Sevillano, D; Valero, E	1
Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y	1
Aguilar, L; Garcia-Mendez, E; Jiménez De Anta, MT; Marco, F; Mensa, J; Ruiz, J; Sierra, JM; Vila, J	1
Chuma, T; Itoh, K; Niwa, H; Okamoto, K	1
Chiang, CH; Lu, DW; Tai, MC	1
Aracil, B; Campos, J; Cantón, R; Pérez-Vázquez, M; Román, F	1
Chuma, T; Maeda, T; Niwa, H; Okamoto, K	1
Chiu, SS; Chow, KH; Ho, AY; Ho, PL; Lai, EL; Lau, YL; Mak, GC; Tsang, KW	1
Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A	1
Kabra, SK; Kadhiravan, T; Kapil, A; Misra, A; Renuka, K; Wig, N	1
Abba, M; Donnelly, J; Hussain, B; Shervington, LA	1
Ho, PL; Lau, SK; Mak, GC; Tse, CW; Wong, SS	1
Arjyal, A; Pandit, A	1
Depta, JP; Pichler, WJ; Schmid, DA	1
Romero, IC; Saravia, NG; Walker, J	1
Debray, M; Dutot, M; Martin, C; Pouzaud, F; Rat, P; Warnet, JM	1
Bilker, WB; Fishman, NO; Lautenbach, E; Mao, X; Metlay, JP; Nachamkin, I; Tolomeo, P	1
Cambau, E; Cattoir, V; Denamur, E; Lascols, C; Legrand, P; Lesprit, P; Soussy, CJ	1
Bay, PV; Farrar, JJ; Hien, TT; Ho, VA; Lanh, MN; Parry, CM; Phuong, le T; Tham, NT; Tung, le T; Wain, J	1
Albert, C; Holzgrabe, U; Waibel, B	1
Ejaz, M; Jabeen, K; Khan, E; Shezad, MF; Siddiqui, J; Zafar, A	1
Gaborieau, V; Marchou, B; Weill, FX	1
Agtini, MD; Arjyal, A; Baker, S; Basnyat, B; Bhattacharya, SK; Bhutta, ZA; Campbell, JI; Canh, DG; Chinh, NT; Clemens, J; Dolecek, C; Dong, B; Dongol, S; Duy, PT; Farrar, JJ; Karkey, A; Naheed, A; Ochiai, L; Parry, CM; Thieu Nga, TV; Thuy, CT; Tinh Hien, T; Van Minh Hoang, N; Vinh, H; Wain, J	1
Ryzhko, IV; Trishina, AV; Verkina, LM	1
Arlet, G; Emond, JP; Smati, M; Tankovic, J	1
Bello-Toledo, H; Domínguez-Yévenes, M; Elgorriaga-Islas, E; García-Cañete, P; González-Rocha, G; Guggiana-Nilo, P; Labarca-Labarca, J; Mella-Montecinos, S	1
Caron, F; Choplin-Renard, J; Etienne, M; Pestel-Caron, M; Van Elslande, H	1
Bedoin, M; Berthelot, P; Boyer, M; Carricajo, A; Cazorla, C; Guérin, T; Lucht, F; Viallon, A	1
Åhman, J; Kahlmeter, G; Matuschek, E; Petersen, A; Sjölund-Karlsson, M; Skov, R; Stegger, M; Torpdahl, M	1
De Silva, BCJ; Heo, GJ; Hossain, S; Pathirana, HNKS; Wimalasena, SHMP	1
Abdelwahab, SI; Dafalla, OME; Homeida, HE; Taha, MME	1
Fazeli, MR; Sepahi, AA; Shariatmadari, F; Zamani, N	1
Adhikary, A; Biswal, S; Chatterjee, D; Ghosh, AS	1

Reviews

4 review(s) available for ofloxacin and nalidixic acid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019
Symposium on antimicrobial agents. The quinolones. Mayo Clinic proceedings, 1987, Volume: 62, Issue:11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Humans; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines	1987
The mode of action of 4-quinolones and possible mechanisms of resistance. The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl D Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines	1986

Trials

4 trial(s) available for ofloxacin and nalidixic acid

Article	Year
[Effect of ofloxacin, ciprofloxacin and nalidixic acid on serum theophylline level in patients treated with methylxanthine preparations]. Pneumonologia i alergologia polska, 1992, Volume: 60, Issue:1-2 Topics: Administration, Oral; Adult; Aminophylline; Asthma; Biological Availability; Ciprofloxacin; Drug Therapy, Combination; Humans; Middle Aged; Nalidixic Acid; Ofloxacin; Theophylline; Time Factors	1992
[Therapeutic potential of ofloxacin in hospital medicine. A French multicenter study]. Pathologie-biologie, 1990, Volume: 38, Issue:5 Topics: Bacteria, Anaerobic; Cross Infection; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Multicenter Studies as Topic; Nalidixic Acid; Ofloxacin; Oxacillin	1990
A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:7 Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Multiple; Female; Humans; Male; Nalidixic Acid; Ofloxacin; Outcome Assessment, Health Care; Pilot Projects; Typhoid Fever	2000
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Blood Cell Count; Child; Child, Preschool; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Salmonella enterica; Treatment Outcome; Typhoid Fever	2007

Other Studies

138 other study(ies) available for ofloxacin and nalidixic acid

Article	Year
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay. Journal of medicinal chemistry, 1986, Volume: 29, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1986
1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity. Journal of medicinal chemistry, 1986, Volume: 29, Issue:4 Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Naphthyridines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1986
DNA gyrase inhibitory activity of ellagic acid derivatives. Bioorganic & medicinal chemistry letters, 1998, Jan-06, Volume: 8, Issue:1 Topics: Ellagic Acid; Enzyme Inhibitors; Escherichia coli; Structure-Activity Relationship; Topoisomerase II Inhibitors	1998
Antibacterial activity of quinolone-macrocycle conjugates. Bioorganic & medicinal chemistry letters, 2003, May-19, Volume: 13, Issue:10 Topics: Anti-Bacterial Agents; Escherichia coli; Heterocyclic Compounds; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus; Structure-Activity Relationship	2003
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones	2003
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5 Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors	2007
Vibrio splendidus as the source of plasmid-mediated QnrS-like quinolone resistance determinants. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Open Reading Frames; Plasmids; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Vibrio	2007
Plasmid-mediated quinolone resistance determinant QnrB4 identified in France in an Enterobacter cloacae clinical isolate coexpressing a QnrS1 determinant. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacter cloacae; Escherichia coli; France; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Plasmids; Quinolones; Transformation, Genetic	2007
Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Anti-Bacterial Agents; Asia; Bangladesh; China; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Microbial; Fluoroquinolones; Humans; India; Indonesia; Laos; Microbial Sensitivity Tests; Mutation; Nepal; Pakistan; Salmonella typhi; Vietnam	2007
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid	2007
Are all the DNA gyrase mutations found in Mycobacterium leprae clinical strains involved in resistance to fluoroquinolones? Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Anti-Infective Agents; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae	2008
Mutagenesis in the alpha3alpha4 GyrA helix and in the Toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Amino Acid Sequence; Antitubercular Agents; DNA Gyrase; Drug Resistance, Bacterial; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Structure, Secondary; Quinolones; Sequence Homology, Amino Acid; Structure-Activity Relationship	2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey	2008
ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Base Sequence; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Quinolones	2008
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin	2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids	2008
qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Cattle; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Quinolones; Salmonella enterica	2009
Characterization of the plasmid-borne quinolone resistance gene qnrB19 in Salmonella enterica serovar Typhimurium. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Evolution, Molecular; Microbial Sensitivity Tests; Multigene Family; Plasmids; Quinolones; Salmonella typhimurium	2009
Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Bacterial Proteins; Drug Resistance, Bacterial; Electroporation; Genotype; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella enterica	2009
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens	2009
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline	2010
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium	2010
Novel variants of the qnrB gene, qnrB22 and qnrB23, in Citrobacter werkmanii and Citrobacter freundii. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Animals; Bacterial Proteins; Chickens; Citrobacter; Citrobacter freundii; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Quinolones; Swine	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Topics: Anti-Bacterial Agents; Azithromycin; Biological Products; Cell Line; Cell Survival; Chlamydophila pneumoniae; Drug Discovery; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure	2017
Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis. European journal of medicinal chemistry, 2020, Dec-01, Volume: 207 Topics: Antitubercular Agents; Drug Design; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenanthrolines; Quinolones	2020
[Comparative activities in vitro of 4 quinolones (nalidixic acid, pefloxacin, norfloxacin, ofloxacin) on 13 bacterial species]. Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie, 1992, Volume: 58 Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Species Specificity	1992
[Resistance to new quinolones among the enterobacteria]. Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie, 1992, Volume: 58 Topics: Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Nalidixic Acid; Ofloxacin; Pefloxacin; Recurrence; Urinary Tract Infections	1992
OmpF channel permeability of quinolones and their comparison with beta-lactams. FEMS microbiology letters, 1992, Aug-01, Volume: 74, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Cell Membrane Permeability; Cephalosporins; Diffusion; Enoxacin; Escherichia coli; Liposomes; Nalidixic Acid; Norfloxacin; Ofloxacin; Stereoisomerism	1992
Biphasic kinetics of bacterial killing by quinolones. The Journal of antimicrobial chemotherapy, 1991, Volume: 27, Issue:3 Topics: Colony Count, Microbial; Escherichia coli; Humans; Infant, Newborn; Models, Theoretical; Nalidixic Acid; Ofloxacin; Pefloxacin	1991
Role of the outer membrane for quinolone resistance in enterobacteria. Chemotherapy, 1990, Volume: 36, Issue:1 Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Escherichia coli; Fleroxacin; Lipopolysaccharides; Nalidixic Acid; Ofloxacin; Serratia marcescens; Species Specificity	1990
[Comparison of the in vitro antibacterial activity of ofloxacin and nalidixic acid]. Mikrobiyoloji bulteni, 1990, Volume: 24, Issue:3 Topics: Acinetobacter; Bacteria; Enterobacteriaceae; Humans; Nalidixic Acid; Ofloxacin; Pseudomonas; Staphylococcus	1990
[Antibacterial activity of norfloxacin, ofloxacin and ciprofloxacin according to resistance phenotypes to nalidixic acid and pefloxacin]. Pathologie-biologie, 1990, Volume: 38, Issue:5 Topics: Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Aerobic Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Phenotype; Staphylococcus aureus	1990
Interactions of the 4-quinolones with other antibacterials. Journal of medical microbiology, 1989, Volume: 29, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Escherichia coli; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin	1989
Serum protein binding of lomefloxacin, a new antimicrobial agent, and its related quinolones. Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:6 Topics: Animals; Anti-Infective Agents; Blood Proteins; Dogs; Fluoroquinolones; Humans; Nalidixic Acid; Ofloxacin; Protein Binding; Quinolones; Rats; Species Specificity	1989
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors	1988
Quinolones, theophylline, and diclofenac interactions with the gamma-aminobutyric acid receptor. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Animals; Ciprofloxacin; Diclofenac; Drug Synergism; GABA Antagonists; In Vitro Techniques; Male; Muscimol; Nalidixic Acid; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Theophylline	1988
The comparative in vitro activity of ofloxacin (RU 43 280) and other quinolone derivatives against 722 bacteria of clinical interest. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Bacteria; Bacteroides fragilis; Clostridium perfringens; Enterobacteriaceae; Fusobacterium; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Structure-Activity Relationship	1987
In-vitro activity of newer quinolones against aerobic bacteria. The Journal of antimicrobial chemotherapy, 1986, Volume: 17 Suppl B Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Calcium; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Magnesium Sulfate; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas; Quinolines; Sulfates; Zinc; Zinc Sulfate	1986
Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile. Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:2 Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Clostridium; Enoxacin; Fluoroquinolones; Humans; Infant, Newborn; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines	1986
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4 Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica	1985
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4 Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae	1985
Comparative in vitro studies with 4-quinolone antimicrobials. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:5 Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones	1985
Comparative antimicrobial activity of enoxacin, ciprofloxacin, amifloxacin, norfloxacin and ofloxacin against 177 bacterial isolates. The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines	1986
In vitro evaluation of A-56619 and A-56620, two new quinolones. Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Piperazines; Quinolines	1986
[In vitro activity of seven gyrase inhibitors of a group of heterocyclic carbonic acids against nonfermenting gram negative rods (nonfermenters)]. Arzneimittel-Forschung, 1985, Volume: 35, Issue:3 Topics: Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Gram-Negative Aerobic Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Pseudomonas aeruginosa; Quinolines; Topoisomerase II Inhibitors	1985
[Gyrase inhibitor]. Klinische Wochenschrift, 1985, Oct-01, Volume: 63, Issue:19 Topics: 4-Quinolones; Anti-Bacterial Agents; Bacteria; Cinoxacin; Drug Resistance, Microbial; Humans; Nalidixic Acid; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors	1985
Clinical uses of nalidixic acid analogues: the fluoroquinolones. European journal of clinical microbiology, 1986, Volume: 5, Issue:2 Topics: Administration, Oral; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Male; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Topoisomerase II Inhibitors	1986
Plasmid "curing" by some recently synthetized 4-quinolone compounds. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:5 Topics: Escherichia coli; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Pefloxacin; Plasmids	1988
Inhibition of plasmid conjugation by some recently synthetized 4-quinolone compounds. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:5 Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Conjugation, Genetic; Escherichia coli; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; R Factors	1988
[Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987]. Mikrobiyoloji bulteni, 1988, Volume: 22, Issue:2 Topics: Ampicillin Resistance; Anti-Bacterial Agents; Ceftriaxone; Chloramphenicol Resistance; Drug Resistance, Microbial; Dysentery, Bacillary; Humans; Nalidixic Acid; Ofloxacin; Prospective Studies; Serotyping; Shigella; Shigella boydii; Shigella flexneri; Shigella sonnei; Streptomycin; Tetracycline Resistance; Trimethoprim, Sulfamethoxazole Drug Combination; Turkey	1988
Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis. The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:6 Topics: Adult; Anti-Infective Agents; DNA; Humans; In Vitro Techniques; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Piromidic Acid	1986
Membrane permeability of Pseudomonas aeruginosa to 4-quinolones. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1987, Volume: 265, Issue:1-2 Topics: Anti-Bacterial Agents; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Polymyxin B; Pseudomonas aeruginosa; Quinolines	1987
In vitro activity of PD 127,391, an enhanced-spectrum quinolone. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Anti-Infective Agents; Bacteria; Cefuroxime; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gentamicins; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Ofloxacin	1988
Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8 Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus	1988
Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants. Chemotherapy, 1985, Volume: 31, Issue:1 Topics: Acinetobacter; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Gentamicins; Haemophilus influenzae; Mezlocillin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus	1985
Comparative in vitro activity of three new quinolone antibiotics against recent clinical isolates. Scandinavian journal of infectious diseases, 1985, Volume: 17, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus	1985
Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens. Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; Cefpirome; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Leucomycins; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines	1985
Antichlamydial activity of quinolone carboxylic acids. The Journal of antimicrobial chemotherapy, 1985, Volume: 15, Issue:5 Topics: Chlamydia trachomatis; Ciprofloxacin; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines	1985
[Effect ofloxacin on Haemophilus influenza, Streptococcus pneumoniae and Neisseria meningitidis. Comparison with similar molecules]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Haemophilus influenzae; Microbial Sensitivity Tests; Nalidixic Acid; Neisseria meningitidis; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Streptococcus pneumoniae	1985
[Comparison of the in vitro activity of 6 quinolones on Pseudomonas sp]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Pseudomonas; Pseudomonas aeruginosa; Quinolines	1985
[Comparative in vitro study of the activity of 5 quinolones against Acinetobacter calcoaceticus]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Topics: Acinetobacter; Ciprofloxacin; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines	1985
[Sensitivity of obligate anaerobes to ofloxacin, pefloxacin, enoxacin and norfloxacin]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Topics: Bacteria, Anaerobic; Bacteroides; Clostridium; Enoxacin; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin	1985
[Comparison of the antibacterial effects of ofloxacin, oxolinic acid and nalidixic acid]. Ceskoslovenska epidemiologie, mikrobiologie, imunologie, 1988, Volume: 37, Issue:5 Topics: Anti-Bacterial Agents; Bacteriuria; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Oxolinic Acid; Pseudomonas	1988
Morphological investigation of osteochondrosis induced by ofloxacin in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1988, Volume: 11, Issue:1 Topics: Animals; Anti-Infective Agents; Bone and Bones; Male; Nalidixic Acid; Ofloxacin; Osteochondritis; Rats; Rats, Inbred Strains	1988
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Pefloxacin; Pipemidic Acid; Proteus; Providencia; Urinary Tract Infections	1988
[Modulation by quinolones of the in vitro proliferative response of splenic cells of the mouse and IL 1 production]. Pathologie-biologie, 1987, Volume: 35, Issue:5 Pt 2 Topics: Animals; Anti-Infective Agents; Cell Division; Cells, Cultured; Ciprofloxacin; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred DBA; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Spleen	1987
Comparative activity of ofloxacin and seven other antimicrobials against urea-splitting microorganisms. Infection, 1986, Volume: 14 Suppl 4 Topics: Anti-Bacterial Agents; Corynebacterium; Enterobacteriaceae; Humans; Hydrogen-Ion Concentration; Nalidixic Acid; Ofloxacin; Oxazines; Staphylococcus; Urea	1986
The sensitivity of gram-negative and gram-positive bacteria to ofloxacin. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperacillin	1987
[Therapeutic contribution of the new quinolones]. La Revue du praticien, 1987, Apr-11, Volume: 37, Issue:21 Topics: Anti-Infective Agents; Bacterial Infections; Biotransformation; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Therapy, Combination; Humans; Kinetics; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin	1987
Influence of antibiotics on intestinal mucin in healthy subjects. European journal of clinical microbiology, 1986, Volume: 5, Issue:6 Topics: Administration, Oral; Adult; Ampicillin; Anti-Bacterial Agents; Bacitracin; Clindamycin; Doxycycline; Drug Combinations; Electrophoresis, Agar Gel; Erythromycin; Feces; Germ-Free Life; Humans; Intestinal Mucosa; Intestines; Metronidazole; Mucins; Nalidixic Acid; Ofloxacin; Oxazines; Random Allocation; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	1986
[Multicenter study of ofloxacin activity on bacteria isolated from a hospital environment]. Pathologie-biologie, 1986, Volume: 34, Issue:5 Topics: Bacteria; Hospitals; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Oxazines	1986
Frequency and expression of mutational resistance to the 4-quinolone antibacterials. Scandinavian journal of infectious diseases. Supplementum, 1986, Volume: 49 Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones	1986
The in-vitro activity of EN 272, a quinolone-7-carboxylic acid, in comparison with other quinolones. The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones; Structure-Activity Relationship; Urinary Tract Infections	1985
Ofloxacin: antibacterial activity, induction of resistance and killing curves. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:4 Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid	1985
Antibacterial activity of ofloxacin and other 4-quinolone derivatives: in-vitro and in-vivo comparison. The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:4 Topics: Animals; Anti-Bacterial Agents; Bacteria; Blood Proteins; Drug Resistance, Microbial; Male; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Protein Binding	1985
[Comparative bacteriologic activity of norfloxacin, ofloxacin and pefloxacin against 320 Gram-negative bacilli resistant and non-resistant to nalidixic acid and cephalosporins]. Pathologie-biologie, 1985, Volume: 33, Issue:5 Pt 2 Topics: Acinetobacter; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pseudomonas aeruginosa	1985
Comparison of the antibacterial in vitro and in vivo activity of ofloxacin (HOE 280 DL 8280) and nalidixic acid analogues. European journal of clinical microbiology, 1983, Volume: 2, Issue:6 Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Drug Resistance, Microbial; Lactams; Mice; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid	1983
Mutational resistance to 4-quinolone antibacterial agents. European journal of clinical microbiology, 1984, Volume: 3, Issue:4 Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Humans; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Species Specificity	1984
In-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid. The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl C Topics: Bacteria; Bacterial Infections; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines	1984
In vitro activity of ciprofloxacin against clinical isolates of Chlamydia trachomatis. European journal of clinical microbiology, 1984, Volume: 3, Issue:4 Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Oxazines; Pefloxacin; Quinolines	1984
Function of the SOS process in repair of DNA damage induced by modern 4-quinolones. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:7 Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Mutation; Nalidixic Acid; Norfloxacin; Ofloxacin; RNA, Bacterial; SOS Response, Genetics	1993
Lack of increase in resistance to quinolones in general practice isolates of Escherichia coli. The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:1 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections	1994
Effects of fluoroquinolones on cultured articular chondrocytes flow cytometric analysis of free radical production. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Animals; Anti-Infective Agents; Cartilage; Cell Survival; Cells, Cultured; Ciprofloxacin; Flow Cytometry; Free Radicals; Macrophages, Alveolar; Nalidixic Acid; Ofloxacin; Pefloxacin; Rabbits	1994
Interference of ofloxacin with determination of urinary porphyrins. Clinical chemistry, 1994, Volume: 40, Issue:3 Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; False Positive Reactions; Humans; Nalidixic Acid; Norfloxacin; Ofloxacin; Porphyrins; Spectrometry, Fluorescence	1994
Comparative study of permeability into rat cerebrospinal fluid of the quinolones: dependency on their lipophilicities. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Injections, Intravenous; Male; Nalidixic Acid; Norfloxacin; Ofloxacin; Rats; Rats, Wistar	1994
Antagonism between bactericidal activities of 4-quinolones and coumarins gives insight into 4-quinolone killing mechanisms. Microbios, 1994, Volume: 77, Issue:311 Topics: Aminocoumarins; Anti-Infective Agents; Ciprofloxacin; Coumarins; DNA Topoisomerases, Type II; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Rifampin	1994
Mathematical model for comparison of time-killing curves. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:8 Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cell Cycle; Cephalothin; Escherichia coli; Kinetics; Mathematical Computing; Microbial Sensitivity Tests; Models, Biological; Nalidixic Acid; Ofloxacin; Pefloxacin; Time Factors	1993
Determination of MICs for staphylococci using the API ATB quinolone and API ATB macrolide systems. Pathologie-biologie, 1993, Volume: 41, Issue:4 Topics: Ciprofloxacin; Clindamycin; Dose-Response Relationship, Drug; Erythromycin; Humans; In Vitro Techniques; Lincomycin; Microbiological Techniques; Nalidixic Acid; Ofloxacin; Pefloxacin; Staphylococcus; Virginiamycin	1993
Mutations responsible for reduced susceptibility to 4-quinolones in clinical isolates of multi-resistant Salmonella typhi in India. The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:5 Topics: Amino Acid Sequence; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinolones; Salmonella typhi	1996
gyrA mutations in high-level fluoroquinolone-resistant clinical isolates of Escherichia coli. The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:3 Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Escherichia coli; Europe; Genetic Variation; Humans; Microbial Sensitivity Tests; Middle East; Mutation; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Sequence Analysis, DNA	1996
False-positive EMIT II opiates from ofloxacin. Therapeutic drug monitoring, 1997, Volume: 19, Issue:1 Topics: Anti-Infective Agents; Antibodies; Ciprofloxacin; Cross Reactions; Enzyme Multiplied Immunoassay Technique; False Positive Reactions; Humans; Morphine; Nalidixic Acid; Norfloxacin; Ofloxacin	1997
Fluoroquinolone antibacterials enhance UVA-induced skin tumors. Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays	1997
Quinolone antibacterials: a new class of photochemical carcinogens. Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3 Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms	1997
Determination of DNA sequences required for regulated Mycobacterium tuberculosis RecA expression in response to DNA-damaging agents suggests that two modes of regulation exist. Journal of bacteriology, 1997, Volume: 179, Issue:11 Topics: Amino Acid Sequence; Base Sequence; DNA Damage; DNA, Bacterial; Gene Expression Regulation, Bacterial; Mitomycins; Molecular Sequence Data; Mycobacterium tuberculosis; Nalidixic Acid; Ofloxacin; Rec A Recombinases; Sequence Analysis, DNA	1997
Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections. Journal of clinical microbiology, 1997, Volume: 35, Issue:9 Topics: Anti-Infective Agents; Asparagine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Humans; Incidence; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Serine; Urinary Tract Infections	1997
The effects of increasing levels of quinolone resistance on in-vitro activity of four quinolones. The Journal of antimicrobial chemotherapy, 1998, Volume: 42, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Quinolones	1998
Cholera in children in Karachi from 1990 through 1995: a study of cases admitted to a tertiary care hospital. JPMA. The Journal of the Pakistan Medical Association, 1998, Volume: 48, Issue:6 Topics: Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Child; Child, Preschool; Cholera; Disease Outbreaks; Drug Resistance, Microbial; Erythromycin; Female; Gastroenteritis; Humans; Infant; Infant, Newborn; Male; Nalidixic Acid; Ofloxacin; Pakistan; Prevalence; Sanitation; Tetracycline Resistance; Vibrio cholerae; Water Supply	1998
Selection of resistant variants of respiratory pathogens by quinolones. International journal of antimicrobial agents, 1999, Volume: 12, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Nalidixic Acid; Ofloxacin; Pneumonia, Bacterial; Streptococcus pneumoniae	1999
Novel action of quinolones on osteoclast-like cells. The Journal of toxicological sciences, 1999, Volume: 24, Issue:5 Topics: Animals; Cells, Cultured; Dinoprostone; Histocytochemistry; Male; Mice; Nalidixic Acid; Norfloxacin; Ofloxacin; Osteoclasts; Quinolones; Spleen; Tumor Necrosis Factor-alpha	1999
Antimicrobial susceptibilities of Campylobacter strains isolated from broilers in the southern part of Japan from 1995 to 1999. The Journal of veterinary medical science, 2001, Volume: 63, Issue:9 Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Cecum; Chickens; Drug Resistance, Microbial; Erythromycin; Japan; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Penicillins; Poultry Diseases; Tetracycline	2001
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4 Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins	2001
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays	2002
In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene. International journal of antimicrobial agents, 2003, Volume: 22, Issue:1 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Genes, Bacterial; Gonorrhea; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Nalidixic Acid; Naphthyridines; Neisseria gonorrhoeae; Ofloxacin; Quinolines	2003
Simultaneous detection of mutations associated with resistance to macrolides and quinolones in Campylobacter jejuni and C. coli using a PCR-line probe assay. International journal of antimicrobial agents, 2003, Volume: 22, Issue:4 Topics: Campylobacter coli; Campylobacter jejuni; Drug Resistance, Bacterial; Erythromycin; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction	2003
Corneal and scleral permeability of quinolones--a pharmacokinetics study. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:6 Topics: Administration, Topical; Animals; Aqueous Humor; Cell Membrane Permeability; Cinoxacin; Ciprofloxacin; Conjunctiva; Cornea; Enoxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Rabbits; Sclera; Time Factors; Water	2003
Laboratory detection of Haemophilus influenzae with decreased susceptibility to nalidixic acid, ciprofloxacin, levofloxacin, and moxifloxacin due to GyrA and ParC mutations. Journal of clinical microbiology, 2004, Volume: 42, Issue:3 Topics: Aza Compounds; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Primers; DNA Topoisomerase IV; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Quinolines	2004
Acquisition of quinolone resistance and point mutation of the gyrA gene in Campylobacter jejuni isolated from broilers and in vitro-induced resistant strains. The Journal of veterinary medical science, 2004, Volume: 66, Issue:2 Topics: Animals; Base Sequence; Campylobacter jejuni; Chickens; DNA Gyrase; DNA Primers; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Norfloxacin; Ofloxacin; Point Mutation; Quinolines; Sequence Analysis, DNA	2004
Decreased levofloxacin susceptibility in Haemophilus influenzae in children, Hong Kong. Emerging infectious diseases, 2004, Volume: 10, Issue:11 Topics: Anti-Bacterial Agents; Carrier State; Child; Child, Preschool; Drug Resistance, Bacterial; Haemophilus influenzae; Hong Kong; Humans; Infant; Levofloxacin; Nalidixic Acid; Nasopharynx; Ofloxacin	2004
Vibrational spectroscopic characterization of fluoroquinolones. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:7 Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water	2005
Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi. BMC infectious diseases, 2005, May-18, Volume: 5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefixime; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; India; Infant; Male; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Salmonella typhi; Treatment Outcome; Typhoid Fever	2005
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation. Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4 Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors	2005
Reduced levofloxacin susceptibility and tetracycline resistance in a clinical isolate of Haemophilus quentini identified by 16S rRNA sequencing. Journal of clinical microbiology, 2005, Volume: 43, Issue:10 Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Typing Techniques; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Haemophilus; Haemophilus Infections; Humans; Infant, Newborn; Levofloxacin; Nalidixic Acid; Ofloxacin; Phenotype; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Tetracycline Resistance	2005
Typhoid and paratyphoid fever. Lancet (London, England), 2005, Nov-05, Volume: 366, Issue:9497 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Nepal; Ofloxacin; Salmonella enterica	2005
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes	2006
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro. The Journal of parasitology, 2005, Volume: 91, Issue:6 Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones	2005
Age-dependent effects on redox status, oxidative stress, mitochondrial activity and toxicity induced by fluoroquinolones on primary cultures of rabbit tendon cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2006, Volume: 143, Issue:2 Topics: Achilles Tendon; Age Factors; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fluoroquinolones; Glutathione; Mitochondria; Nalidixic Acid; Ofloxacin; Oxidation-Reduction; Oxidative Stress; Pefloxacin; Rabbits; Reactive Oxygen Species	2006
Phenotypic and genotypic characterization of fecal Escherichia coli isolates with decreased susceptibility to fluoroquinolones: results from a large hospital-based surveillance initiative. The Journal of infectious diseases, 2006, Jul-01, Volume: 194, Issue:1 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Feces; Fluoroquinolones; Genotype; Hospitals; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Phenotype; Population Surveillance; Solvents	2006
In vivo selection during ofloxacin therapy of Escherichia coli with combined topoisomerase mutations that confer high resistance to ofloxacin but susceptibility to nalidixic acid. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:5 Topics: Aged; Anti-Bacterial Agents; Bacteremia; DNA Topoisomerases; Drug Resistance; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Male; Nalidixic Acid; Ofloxacin	2006
Evaluation of the extent of protein binding by means of NMR diffusion and relaxation experiments, and automated continuous ultrafiltration. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Jun-28, Volume: 37, Issue:3-4 Topics: Algorithms; Anti-Bacterial Agents; Diffusion; Fluoroquinolones; Gatifloxacin; Magnetic Resonance Spectroscopy; Nalidixic Acid; Ofloxacin; Protein Binding; Serum Albumin, Bovine; Solutions; Ultrafiltration	2009
Trends in antimicrobial resistance in Shigella species in Karachi, Pakistan. Journal of infection in developing countries, 2009, Dec-15, Volume: 3, Issue:10 Topics: Adolescent; Adult; Age Factors; Ampicillin; Anti-Infective Agents; Ceftriaxone; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Dysentery, Bacillary; Humans; Infant; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Pakistan; Shigella; Trimethoprim, Sulfamethoxazole Drug Combination	2009
[A case of Salmonella enterica serovar typhi with decreased susceptibility to ciprofloxacin]. Medecine et maladies infectieuses, 2010, Volume: 40, Issue:12 Topics: Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; India; Male; Microbial Sensitivity Tests; Middle Aged; Nalidixic Acid; Ofloxacin; Randomized Controlled Trials as Topic; Recurrence; Salmonella paratyphi A; Salmonella typhi; Travel; Typhoid Fever	2010
Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Salmonella typhi	2010
[Lack of levofloxacin and moxyfloxacin efficacy in experimental plague of albino mice infected with nalidixic acid resistant pathogen (Nal(r))]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2010, Volume: 55, Issue:11-12 Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Lethal Dose 50; Levofloxacin; Mice; Models, Animal; Nalidixic Acid; Ofloxacin; Plague; Virulence; Yersinia pestis	2010
In vivo sequential selection of Escherichia coli with topoisomerase- and efflux-mediated misleading quinolone resistance phenotypes. Microbial drug resistance (Larchmont, N.Y.), 2012, Volume: 18, Issue:1 Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type I; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Phenotype; Quinolones; Selection, Genetic; Sequence Analysis, DNA	2012
[Prevalence of plasmid-mediated quinolone resistance determinant aac(6')-Ib-cr among ESBL producing enterobacteria isolates from Chilean hospitals]. Enfermedades infecciosas y microbiologia clinica, 2012, Volume: 30, Issue:8 Topics: Acetylation; Anti-Bacterial Agents; Bacterial Proteins; Chile; Ciprofloxacin; Cross Infection; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Fluoroquinolones; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Nalidixic Acid; Ofloxacin; Polymorphism, Restriction Fragment Length; R Factors; Sequence Analysis, DNA; Substrate Specificity	2012
Antibiotic resistance in adult female patients hospitalized for acute pyelonephritis: rates and predicting factors. Medecine et maladies infectieuses, 2014, Volume: 44, Issue:5 Topics: Acute Disease; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Catchment Area, Health; Cephalosporins; Cohort Studies; Comorbidity; Cross Infection; Drug Resistance, Multiple, Bacterial; Emergency Service, Hospital; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; France; Hospitalization; Hospitals, Teaching; Hospitals, Urban; Humans; Institutionalization; Long-Term Care; Middle Aged; Nalidixic Acid; Ofloxacin; Pyelonephritis; Retrospective Studies; Risk Factors	2014
Risk factors for quinolone-resistance in women presenting with Escherichia coli acute pyelonephritis. Medecine et maladies infectieuses, 2014, Volume: 44, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catchment Area, Health; Cohort Studies; Community-Acquired Infections; Comorbidity; Drug Resistance, Multiple, Bacterial; Emergency Service, Hospital; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; France; Hospitalization; Hospitals, Teaching; Hospitals, Urban; Humans; Institutionalization; Long-Term Care; Middle Aged; Nalidixic Acid; Ofloxacin; Pyelonephritis; Retrospective Studies; Risk Factors; Young Adult	2014
Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica. Journal of clinical microbiology, 2015, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Bacteremia; Base Sequence; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Nalidixic Acid; Ofloxacin; Pefloxacin; Salmonella enterica; Salmonella Infections; Sequence Analysis, DNA	2015
Prevalence and characterisation of quinolone resistance genes in Aeromonas spp. isolated from pet turtles in South Korea. Journal of global antimicrobial resistance, 2017, Volume: 11 Topics: Aeromonas; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Plasmids; Polymerase Chain Reaction; Quinolones; Republic of Korea; Turtles	2017
Multidrug resistance, prevalence and phylogenetic analysis of genes encoding class II and III integrons in clinically isolated Escherichia coli. Cellular and molecular biology (Noisy-le-Grand, France), 2018, Apr-30, Volume: 64, Issue:5 Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Base Sequence; Cefotaxime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation, Bacterial; Gentamicins; Hospitals; Humans; Imipenem; Integrons; Microbial Sensitivity Tests; Nalidixic Acid; Ofloxacin; Phylogeny; Polymerase Chain Reaction; Prevalence; Saudi Arabia; Sequence Alignment	2018
A new probiotic Lactobacillus plantarum strain isolated from traditional dairy together with nanochitosan particles shows the synergistic effect on aflatoxin B1 detoxification. Archives of microbiology, 2022, Sep-16, Volume: 204, Issue:10 Topics: Aflatoxin B1; Anti-Bacterial Agents; Chitosan; Erythromycin; Fusidic Acid; Gentamicins; Kanamycin; Lactobacillales; Lactobacillus plantarum; Nalidixic Acid; Neomycin; Ofloxacin; Probiotics; Vancomycin	2022
A NiCoT family metal transporter of Microbiology (Reading, England), 2022, Volume: 168, Issue:10 Topics: Anti-Bacterial Agents; Bacterial Proteins; Cobalt; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Ethambutol; Gentamicins; Isoleucine; Isoniazid; Kanamycin; Leucine; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Neomycin; Nickel; Norfloxacin; Ofloxacin	2022