ofloxacin and methicillin

ofloxacin has been researched along with methicillin in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.29)18.7374
1990's6 (21.43)18.2507
2000's17 (60.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cobbs, CG; Smith, KR1
Coste-Burel, M; Espaze, EP; Reynaud, AE; Richet, H1
Albrecht, LM; Barriere, SL; Kaatz, GW; Rybak, MJ; Seo, SM1
Smith, SM1
Breyer, S; Georgopoulos, A; Hirschl, AM; Rotter, ML; Stanek, G1
Konno, M1
Canić-Radojlović, M; Mraović, M1
Inoue, Y; Jinbo, Y; Kondo, H; Sakamoto, F; Taguchi, M; Tsukamoto, G1
Eliopoulos, GM; Moellering, RC; Wennersten, CB1
Chiba, A; Harada, S; Hasegawa, M; Kaneko, A; Kobayashi, I; Koyama, H; Matsuzaki, K; Omika, K; Sasaki, J; Sato, Y1
Bonfiglio, G; Cafiso, V; Campanile, F; Messina, C; Santagati, M; Stefani, S1
Calhoun, JH; Mader, JT; Shirtliff, ME1
Barrett, JF; Frosco, M; Ho, H; Lawrence, LE; Mazzucco, CE; Ryan, BM; Warr, G1
Fujita, A; Inagaki, K; Inatomi, T; Kinoshita, S; Koizumi, N; Sano, Y; Sotozono, C1
Cetin, CB; Cosar, G; Dinç, G; Ermertcan, S; Limoncu, MH1
Alfonso, EC; Marangon, FB; Miller, D; Muallem, MS; Romano, AC1
Arnold, FW; Wojda, B1
Bes, M; Etienne, J; Forey, F; Lina, G; Meugnier, H; Ramdani-Bouguessa, N; Reverdy, ME; Tazir, M; Vandenesch, F1
Bosso, JA; Mauldin, PD1
Fukaya, Y; Hirata, H; Kamata, Y; Kambara, Y; Kurasawa, N; Kurita, A; Naito, A; Nakaya, S; Ohashi, Y; Sato, M; Shirasawa, E; Toyoda, Y; Tsuruga, H; Wada, T1
Ariza, J; Cabellos, C; Doménech, A; Garcia, A; Gudiol, F; Murillo, O; Tubau, F1
Donnenfeld, ED; Ehrenhaus, M; Maloney, RK; Manche, EE; Matzkin, DC; Moshirfar, M; Mozayeni, RM; Perry, HD; Rubinfeld, RS; Solomon, KD; Solomon, R; Wittpenn, JR1
Järvinen, A; Kardén-Lilja, M; Kuusela, P; Ruotsalainen, E; Sarna, S; Valtonen, V; Virolainen-Julkunen, A; Vuopio-Varkila, J1
Fantin, B; Massias, L; Muller-Serieys, C; Saleh Mghir, A1
Barraud, O; Brakbi, Y; Cypierre, A; Dubos, M; Fedou, AL; François, B; Fredon, F; Laurent, F1

Reviews

1 review(s) available for ofloxacin and methicillin

ArticleYear
[Refractory respiratory tract infections. 6. New problems in refractory respiratory tract infections. c. Chemotherapy of methicillin-resistant Staphylococci infection].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:3

    Topics: Anti-Bacterial Agents; Cefmetazole; Cephamycins; Drug Therapy, Combination; Fosfomycin; Humans; Methicillin; Minocycline; Ofloxacin; Oxazines; Penicillin Resistance; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus epidermidis; Tetracyclines

1987

Trials

1 trial(s) available for ofloxacin and methicillin

ArticleYear
Methicillin-sensitive Staphylococcus aureus bacteraemia and endocarditis among injection drug users and nonaddicts: host factors, microbiological and serological characteristics.
    The Journal of infection, 2008, Volume: 56, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Case-Control Studies; Electrophoresis, Gel, Pulsed-Field; Endocarditis, Bacterial; Fluoroquinolones; Genotype; Humans; Methicillin; Middle Aged; Naphthyridines; Ofloxacin; Serologic Tests; Staphylococcal Infections; Staphylococcus aureus; Substance Abuse, Intravenous; Teichoic Acids

2008

Other Studies

26 other study(ies) available for ofloxacin and methicillin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:1

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis

1992
[In vitro kinetics of the activity of fusidic acid and fluoroquinolones combinations against staphylococci according to methicillin-resistance phenotype. Implications for the treatment of osteoarticular infections].
    Pathologie-biologie, 1992, Volume: 40, Issue:5

    Topics: Bone Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fusidic Acid; Humans; In Vitro Techniques; Joint Diseases; Methicillin; Methicillin Resistance; Ofloxacin; Pefloxacin; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis

1992
Efficacy of ofloxacin in experimental Staphylococcus aureus endocarditis.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:2

    Topics: Animals; Drug Resistance, Microbial; Endocarditis, Bacterial; Female; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Staphylococcal Infections; Vancomycin

1990
In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Methicillin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperazines; Quinolines; Staphylococcus aureus

1986
Efficacy of coumermycin, ofloxacin and vancomycin against methicillin-resistant Staphylococcus aureus in vitro and in experimental infections of mice.
    Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1988, Volume: 267, Issue:4

    Topics: Aminocoumarins; Animals; Anti-Bacterial Agents; Coumarins; Drug Resistance, Microbial; Male; Methicillin; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Oxazines; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

1988
The activity of ofloxacin against methicillin-resistant Staphylococcus aureus.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Bacterial Agents; Humans; Methicillin; Ofloxacin; Oxazines; Penicillin Resistance; Staphylococcus aureus

1986
Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterials.
    Journal of medicinal chemistry, 1994, Mar-04, Volume: 37, Issue:5

    Topics: Animals; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicillin; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcal Infections; Thiazoles; Topoisomerase II Inhibitors

1994
Comparative in vitro activity of levofloxacin and ofloxacin against gram-positive bacteria.
    Diagnostic microbiology and infectious disease, 1996, Volume: 25, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacteria; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Molecular Sequence Data; Ofloxacin; Penicillins; Staphylococcus; Streptococcus; Vancomycin

1996
[In vitro activities of levofloxacin and other antibiotics against fresh clinical isolates].
    The Japanese journal of antibiotics, 1999, Volume: 52, Issue:9

    Topics: Ampicillin; Anti-Infective Agents; Bacteria; Bacterial Infections; Cefaclor; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Humans; Levofloxacin; Methicillin; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillins

1999
In vitro activity of levofloxacin against coagulase-positive and -negative staphylococci.
    Drugs under experimental and clinical research, 2001, Volume: 27, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Staphylococcus

2001
Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:2

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Humans; Infusions, Parenteral; Levofloxacin; Methicillin; Nafcillin; Ofloxacin; Osteomyelitis; Penicillins; Rabbits; Staphylococcal Infections; Tibia

2001
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2002, Volume: 21, Issue:1

    Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Sensitivity and Specificity; Staphylococcus aureus

2002
Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis infections in the cornea.
    Cornea, 2002, Volume: 21, Issue:7 Suppl

    Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Child; Dibekacin; Eye Infections, Bacterial; Female; Humans; Incidence; Keratitis; Male; Methicillin; Methicillin Resistance; Middle Aged; Ofloxacin; Prevalence; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Vancomycin

2002
Emergence of phenotypic resistance to ciprofloxacin and levofloxacin in methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains.
    International journal of antimicrobial agents, 2003, Volume: 21, Issue:5

    Topics: Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Phenotype; Serial Passage; Staphylococcus aureus

2003
Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis.
    American journal of ophthalmology, 2004, Volume: 137, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Keratitis; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus

2004
An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureus.
    The Journal of the Kentucky Medical Association, 2005, Volume: 103, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Cefazolin; Clindamycin; Community-Acquired Infections; Erythromycin; Female; Humans; Kentucky; Levofloxacin; Male; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Oxacillin; Rifampin; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Sulfamethoxazole; Tetracycline; Trimethoprim; Vancomycin

2005
Detection of methicillin-resistant Staphylococcus aureus strains resistant to multiple antibiotics and carrying the Panton-Valentine leukocidin genes in an Algiers hospital.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:3

    Topics: Algeria; Alleles; Anti-Bacterial Agents; Bacterial Toxins; Community-Acquired Infections; Drug Resistance, Multiple; Exotoxins; Genes, Bacterial; Gentamicins; Hospitals; Humans; Leukocidins; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus

2006
Using interrupted time series analysis to assess associations of fluoroquinolone formulary changes with susceptibility of gram-negative pathogens and isolation rates of methicillin-resistant Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Escherichia coli; Fluoroquinolones; Formularies as Topic; Gatifloxacin; Gram-Negative Bacteria; Humans; Levofloxacin; Methicillin; Methicillin Resistance; Ofloxacin; Pseudomonas aeruginosa; Regression Analysis; Retrospective Studies; Staphylococcus aureus

2006
Antibiotic effects of WP-0405, a thermo-setting ofloxacin gel, on methicillin-resistant Staphylococcus aureus keratitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Ciliary Body; Colony Count, Microbial; Conjunctiva; Cornea; Disease Models, Animal; Eye Infections, Bacterial; Gels; Keratitis; Male; Methicillin; Methicillin Resistance; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tissue Distribution

2006
[Otitis externa: which antibiotics are first choice?].
    MMW Fortschritte der Medizin, 2006, Aug-17, Volume: 148, Issue:33-34

    Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Clindamycin; Drug Therapy, Combination; Humans; Methicillin; Ofloxacin; Ointments; Otitis Externa; Trimethoprim, Sulfamethoxazole Drug Combination

2006
Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:12

    Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cloxacillin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Foreign-Body Reaction; Humans; Levofloxacin; Linezolid; Male; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin

2006
Methicillin-resistant Staphylococcus aureus infectious keratitis following refractive surgery.
    American journal of ophthalmology, 2007, Volume: 143, Issue:4

    Topics: Adult; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Health Personnel; Humans; Keratomileusis, Laser In Situ; Lasers, Excimer; Male; Methicillin; Methicillin Resistance; Middle Aged; Ofloxacin; Photorefractive Keratectomy; Postoperative Complications; Refractive Surgical Procedures; Retrospective Studies; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Surgical Flaps; Vancomycin

2007
Bactericidal activity of the combination of levofloxacin with rifampin in experimental prosthetic knee infection in rabbits due to methicillin-susceptible Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Humans; Knee Prosthesis; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Prosthesis-Related Infections; Rabbits; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome

2009
Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidin.
    BMC infectious diseases, 2014, Aug-27, Volume: 14

    Topics: Abscess; Bacterial Toxins; Exotoxins; Humans; Leukocidins; Magnetic Resonance Imaging; Male; Methicillin; Ofloxacin; Sepsis; Soft Tissue Infections; Staphylococcal Infections; Tomography, X-Ray Computed; Ultrasonography; Young Adult

2014