ofloxacin has been researched along with lomefloxacin in 145 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (6.90) | 18.7374 |
| 1990's | 45 (31.03) | 18.2507 |
| 2000's | 49 (33.79) | 29.6817 |
| 2010's | 35 (24.14) | 24.3611 |
| 2020's | 6 (4.14) | 2.80 |
| Authors | Studies |
|---|---|
| Sasabe, H; Sugiyama, Y; Tsuji, A | 1 |
| Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
| Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW | 1 |
| Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A | 1 |
| Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Sen, S; Sinha, N | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Chen, J; Chen, X; Huang, L; Li, X; Sun, Y | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E | 1 |
| Huang, L; Li, X; Meng, F; Miao, H; Sun, Y | 1 |
| Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW | 1 |
| Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E | 1 |
| Jiang, N; Kong, LY; Lan, JS; Li, F; Wang, J; Wang, X; Wang, ZM; Wu, JJ; Xie, SS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW | 1 |
| Cai, P; Kong, L; Liu, Q; Wang, KDG; Wang, X; Wang, Z; Wu, J; Yang, X | 1 |
| Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Ding, Y; Lan, JS; Liu, J; Liu, Y; Miao, ZY; Xie, SS; Yang, J; Zhang, T | 1 |
| Cai, P; Kong, LY; Li, F; Liu, QH; Wang, J; Wang, XB; Wu, JJ; Yang, XL | 1 |
| Dong, SN; Gong, Q; Li, J; Li, XK; Liu, WW; Mao, F; Tang, Y; Wang, H; Wang, TD; Xu, YX; Zhang, HY; Zhu, J | 1 |
| Huang, Q; Jiang, N; Li, Q; Liang, N; Liu, J; Xie, SS | 1 |
| An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T | 1 |
| Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Blaskovich, MAT; Pham, TDM; Ziora, ZM | 1 |
| Chen, L; Chen, Y; Duan, Y; Feng, F; Huang, J; Jiang, X; Liu, C; Liu, W; Qu, W; Sun, H; Wang, Y; Zhou, J | 1 |
| Chen, T; Chen, Y; Feng, F; Jiang, X; Li, Q; Liu, C; Liu, W; Lyu, W; Sun, H; Wang, S; Wang, Y; Xing, C | 1 |
| Huang, M; Jiang, N; Kong, LY; Lan, JS; Wang, XB; Yin, FC | 1 |
| Ji, L; Kong, L; Li, S; Liu, X; Lu, D; Luo, H; Peng, W; Qu, L; Wang, C; Wang, X; Yin, F | 1 |
| Chen, L; Lei, Z; Sun, J; Sun, X; Wang, Y; Yue, S | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Debbia, EA; Pesce, A; Schito, GC | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Jones, RN | 1 |
| Bornigia, S; De Sio, G; Morbiducci, V; Piersimoni, C; Scalise, G | 1 |
| Bartlett, RC; Mazens-Sullivan, MF; McCarter, YS | 1 |
| Sato, H; Simanjuntak, MT; Tamai, I; Terasaki, T; Tsuji, A | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Barry, AL; Fuchs, PC | 1 |
| Cartwright, FD; Kenny, GE | 1 |
| Kamisaka, K; Kawahara, S; Kibata, M; Matsuyama, T; Mishima, Y; Nagare, J; Nakada, H; Tada, A; Yoshimoto, S | 1 |
| Allen, RA; Amyes, SG; Lewin, CS | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Matsumoto, F; Morita, M; Takahashi, T | 1 |
| Glupczynski, Y; Grenier, P; Pierard, D; Van der Auwera, P | 1 |
| Kato, H; Nagata, O; Nakamura, M; Okezaki, E; Terasaki, T; Tsuji, A | 1 |
| Andrews, JM; Ashby, JP; Matthews, RS; Wise, R | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Nagayama, A; Nakao, T; Taen, H | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Kato, H; Nagata, O; Okezaki, E; Sato, H; Tsuji, A; Yamamoto, S | 1 |
| Nishino, T; Obana, Y | 1 |
| Hirose, T; Inoue, M; Ito, Y; Kato, H; Mitsuhashi, S; Okezaki, E | 1 |
| Beskid, G; Prosser, BL | 2 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| Fujita, H; Matsuo, I | 1 |
| Kudo, M; Ohkubo, T; Sawada, Y; Sugawara, K | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Belliveau, P; Crowe, H; Gousee, G; Nightingale, CH; Quintiliani, R | 1 |
| Spivey, IM | 1 |
| Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Cheung, MM; Ho, NK; Kam, KM; Wong, PW | 1 |
| Kunichan, AD; Mozhokina, GN; Shapatava, MN | 1 |
| Ballesta, S; García, I; Pascual, A; Perea, EJ | 1 |
| Klecak, G; Urbach, F; Urwyler, H | 1 |
| Forbes, PD; Mäkinen, M; Stenbäck, F | 1 |
| Arakane, K; Hirobe, M; Mashiko, S; Nagano, T; Ryu, A; Umezawa, N | 1 |
| Choi, EC; Kang, JA; Kim, BK; Kim, JH; Kim, JW; Kim, YG; Lee, JH | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Choi, EC; Choi, KH; Kim, BK; Kim, JH; Kim, JW; Lee, JH | 1 |
| Callery-D'Amico, S; Cox, CE; Fowler, CL; Kim, SS; King, W; Klimberg, IW | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
| Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG | 1 |
| Andriukhin, MI; Avdoshin, VL; Derevianko, II; Gabliia, MIu; Khodyreva, LA | 1 |
| Albini, A; Fasani, E; Profumo, A | 1 |
| Anjo, S; Hara, A; Nakamura, M; Sakai, M | 1 |
| Fukuda, M; Sasaki, K; Yoshitake, Y | 1 |
| El'kun, GB | 1 |
| Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I | 1 |
| Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S | 1 |
| Belousov, IuB; Efremenkova, OV; Sokolov, AV; Tishenkova, IF | 1 |
| Drusano, GL | 1 |
| Castell, JV; Morlière, P; Ouédraogo, G; Santus, R | 1 |
| Ahr, HJ; Blotz, A; Blümel, J; Dubertret, L; Michel, L; Moysan, A; Vohr, HW | 1 |
| Bai, ZZ; Guan, DW; Zhang, QS | 1 |
| Iwatsu, M; Kanai, A; Sado, K; Tian, X | 1 |
| Baumann-Wilschke, I; Rücker, M; Shakibaei, M; Stahlmann, R | 1 |
| Schaeffer, AJ | 1 |
| Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y | 1 |
| Furuhama, K; Itoh, S; Katoh, M | 1 |
| Chiang, SR; Chuang, YC; Ko, WC; Lee, HC; Tang, HJ; Wang, YY | 1 |
| Ono, C; Tanaka, M | 1 |
| Kawai, M; Mashima, Y; Mochizuki, H; Yamada, K; Yamada, M | 1 |
| Maĭchuk, IuF | 1 |
| Hong, JW; Hu, CQ; Sheng, LS | 1 |
| Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T | 1 |
| Naber, KG | 1 |
| Hatano, K | 1 |
| Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A | 1 |
| Hasegawa, M; Kobayashi, I; Koyama, H; Matsuzaki, K; Sato, Y; Watabe, E | 1 |
| Paramasivan, CN; Rahman, F; Sulochana, S | 1 |
| Abba, M; Donnelly, J; Hussain, B; Shervington, LA | 1 |
| Artemenko, N; Gorelov, A; Perekalina, T; Smelov, V; Smelova, N; Ukleeva, G | 1 |
| Kassab, NM; Kedor-Hackmam, ER; Santoro, MI; Singh, AK | 1 |
| Azadian, BS; Roberts, AP; Talboys, CA | 1 |
| Depta, JP; Pichler, WJ; Schmid, DA | 1 |
| Romero, IC; Saravia, NG; Walker, J | 1 |
| Ishikawa, K; Kawai, M; Mochizuki, H; Yamada, M | 1 |
| Bayar, B; Bozkurt, A; Dinçel, A; Duman, S; Kaya, E; Oflu, Y; Yağci, R; Yağci, S | 1 |
| Baeyens, WR; Ouyang, J; Yang, Y; Zhao, H; Zhou, S | 1 |
| Ni, YN; Zhang, GW | 1 |
| Andreeva, I; Rafalsky, V; Rjabkova, E | 1 |
| Huang, CH; Zhang, H | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Fukumori, S; Hashimoto, Y; Murata, T; Taguchi, M; Tahara, K; Takaai, M | 1 |
| Baeyens, WR; Fei, G; He, L; Huang, C; Ouyang, J; Wang, Y | 1 |
| Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M | 1 |
| Du, S; Kokot, S; Ni, Y | 1 |
| Carda-Broch, S; Esteve-Romero, J; Rambla-Alegre, M | 1 |
| Anisimov, BI; Ryzhko, IV; Trishina, AV; Tsuraeva, RI | 1 |
| Alves, G; Falcão, A; Fortuna, A; Lino, C; Pena, A; Sousa, J | 1 |
| Du, J; Liu, B; Qin, X; Wang, H; Yan, H | 1 |
| Lv, Y; Qiao, J; Wang, H; Yan, H | 1 |
| Cui, YF; He, JT; Qiao, XC; Su, SH; Yang, L | 2 |
| Amoli-Diva, M; Hajjaran, S; Pourghazi, K | 1 |
| Dai, LL; Dai, XH; Li, N; Liu, HJ; Xue, YG; Yan, H | 1 |
| Liu, X; Miao, Q; Song, S; Sun, J; Wang, Y; Xu, M; Zhang, P; Zhao, D; Zhong, L | 1 |
| Fu, Q; Gao, D; Liu, Y; Wang, L; Xia, Z; Yang, F; Zhang, K | 1 |
8 review(s) available for ofloxacin and lomefloxacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Quinolone antibiotics.
Topics: | 2019 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Oral ciprofloxacin, ofloxacin, and lomefloxacin as alternatives to intravenous antimicrobial therapy.
Topics: Administration, Oral; Anti-Bacterial Agents; Ciprofloxacin; Drug Costs; Drug Tolerance; Female; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Cocci; Humans; Male; Ofloxacin; Quinolones; Treatment Outcome | 1993 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Levofloxacin in the treatment of urinary tract infections and prostatitis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2004 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
6 trial(s) available for ofloxacin and lomefloxacin
| Article | Year |
|---|---|
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Urinary Tract Infections | 1998 |
[Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns].
Topics: Adolescent; Adult; Anti-Infective Agents; Burns; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Pseudomonas Infections; Quinolones; Staphylococcal Infections | 1998 |
[Efficacy of lomefloxacin in treatment of nonspecific inflammatory diseases and in prophylaxis of postoperative complications in urology].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Postoperative Complications; Quinolones; Urinary Tract Infections; Urologic Surgical Procedures | 1998 |
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Quinolones; Sinusitis; Treatment Outcome | 1999 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones | 2000 |
[The importance of fluoroquinolones in treating pneumonia in the elderly].
Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Quinolones; Sputum; Time Factors | 1999 |
131 other study(ies) available for ofloxacin and lomefloxacin
| Article | Year |
|---|---|
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
Topics: Animals; Anti-Infective Agents; Bile; Biological Transport, Active; Fluoroquinolones; Glucuronates; Glutathione; Hyperbilirubinemia; Male; Piperazines; Quinolones; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley | 1998 |
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation.
Topics: Animals; Antitubercular Agents; Combinatorial Chemistry Techniques; DNA Gyrase; Enzyme Inhibitors; Fluoroquinolones; Gatifloxacin; Lung; Mice; Molecular Structure; Mycobacterium tuberculosis; Ofloxacin; Spleen; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2008 |
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli.
Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin | 2008 |
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens | 2009 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies | 2014 |
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins | 2014 |
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates | 2014 |
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship | 2014 |
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi | 2015 |
Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Cholinesterases; Coumarins; Donepezil; Dose-Response Relationship, Drug; Drug Design; Eels; Humans; Indans; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Piperidines; Structure-Activity Relationship | 2016 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2016 |
Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Parkinson Disease; Rats; Small Molecule Libraries; Structure-Activity Relationship | 2016 |
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species | 2017 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Donepezil; Drug Design; Electrophorus; Humans; Indans; Mice; Molecular Docking Simulation; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Piperidines; Protein Aggregates; Pyridinium Compounds; Rats; Structure-Activity Relationship | 2017 |
Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Binding Sites; Blood-Brain Barrier; Chromones; Copper; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; Structure-Activity Relationship | 2017 |
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imidazoles; Mice; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Propylamines; Pyrimidines; Rats; Scopolamine; Structure-Activity Relationship; Thiourea | 2018 |
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Aggregates; Range of Motion, Articular; Structure-Activity Relationship; Thiocarbamates | 2018 |
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram | 2019 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine | 2019 |
Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease.
Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Glycogen Synthase Kinase 3; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Morris Water Maze Test; Phosphorylation; Protein Conformation; tau Proteins; Thiazoles | 2020 |
Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Glycogen Synthase Kinase 3 beta; Humans; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Pyridines; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2021 |
Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease.
Topics: | 2020 |
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Azoles; Binding Sites; Blood-Brain Barrier; Cyclic S-Oxides; Drug Design; Humans; Interleukin-6; Isoindoles; Ligands; Mitochondria; Molecular Docking Simulation; Neuroprotective Agents; NF-E2-Related Factor 2; Organoselenium Compounds; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Selenium; Signal Transduction; Thiadiazines | 2021 |
Development of 5-hydroxyl-1-azabenzanthrone derivatives as dual binding site and selective acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Binding Sites; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Rats | 2022 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Time Factors | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1992 |
The comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents.
Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
Transport of the new quinolone antibacterial agents of lomefloxacin and ofloxacin by rat erythrocytes, and its relation to the nicotinic acid transport system.
Topics: Animals; Anti-Infective Agents; Biological Transport, Active; Erythrocytes; Fluoroquinolones; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Niacin; Ofloxacin; Osmolar Concentration; Quinolones; Rats; Rats, Inbred Strains; Temperature | 1991 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
Cross-resistance and cross-susceptibility between fluoroquinolone agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Quinolones | 1991 |
Susceptibility of Mycoplasma pneumoniae to several new quinolones, tetracycline, and erythromycin.
Topics: Anti-Infective Agents; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Quinolones; Tetracycline | 1991 |
[In vitro activities of newly developed quinolones, fleroxacin, lomefloxacin and sparfloxacin against Mycobacterium tuberculosis].
Topics: Anti-Infective Agents; Antitubercular Agents; Fleroxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1991 |
Antibacterial activity of fluoroquinolones in combination with zidovudine.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Salmonella; Staphylococcus; Zidovudine | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin.
Topics: Aeromonas; Anti-Infective Agents; Campylobacter; Corynebacterium; Enterobacteriaceae; Fluoroquinolones; Haemophilus; Neisseria gonorrhoeae; Ofloxacin; Pefloxacin; Quinolones; Staphylococcus aureus | 1989 |
Serum protein binding of lomefloxacin, a new antimicrobial agent, and its related quinolones.
Topics: Animals; Anti-Infective Agents; Blood Proteins; Dogs; Fluoroquinolones; Humans; Nalidixic Acid; Ofloxacin; Protein Binding; Quinolones; Rats; Species Specificity | 1989 |
In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Blood Proteins; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Ofloxacin; Oxazines; Protein Binding; Pseudomonas aeruginosa; Quinolines; Quinolones; Staphylococcus; Streptococcus; Trimethoprim | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Entry of the new quinolone antibacterial agents of ofloxacin and NY-198 into the central nervous system in rats.
Topics: Animals; Anti-Infective Agents; Blood-Brain Barrier; Brain; Fluoroquinolones; Male; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinolones; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Pyelonephritis; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1988 |
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones | 1987 |
Multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
The determination of ofloxacin in human skin tissue by high-performance liquid chromatography and correlation between skin tissue concentration and serum level of ofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Ofloxacin; Quinolones; Skin | 1994 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Criteria for use of ofloxacin and lomefloxacin in adult inpatients and outpatients.
Topics: Adult; Anti-Infective Agents; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Infections; Ofloxacin; Pseudomonas Infections; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1993 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Reference Standards | 1996 |
[Effect of drugs of the fluoroquinolone series on morphokinetic parameters of the cellular elements of lung tissue].
Topics: Animals; Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Techniques; Dogs; Fluoroquinolones; Guinea Pigs; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ofloxacin; Quinolones | 1996 |
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells].
Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature | 1996 |
Fluoroquinolone antibacterials enhance UVA-induced skin tumors.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays | 1997 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms | 1997 |
Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA; DNA Damage; Enoxacin; Fluoroquinolones; Free Radical Scavengers; Hematoporphyrins; Molecular Structure; Ofloxacin; Oxygen; Photosensitizing Agents; Quinolones; Reactive Oxygen Species; Spectroscopy, Near-Infrared; Superoxides | 1997 |
In vitro and in vivo antibacterial efficacies of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Culture Media; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
Structure and medium-dependent photodecomposition of fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Enoxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Photosensitizing Agents; Quantum Theory; Quinolones; Structure-Activity Relationship | 1998 |
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature | 1999 |
[The uptake of fluoroquinolone agent drugs by cultured human conjunctival epithelial cells and cultured SIRC rabbit corneal cells].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Conjunctiva; Cornea; Epithelial Cells; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Rabbits | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
Fluoroquinolone pharmacodynamics: prospective determination of relationships between exposure and outcome.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Models, Biological; Mutation; Neutropenia; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Rats; Treatment Outcome | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Analyses of cutaneous fluoroquinolones photoreactivity using the integrated model for the differentiation of skin reactions.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents; Biomarkers; Cell Membrane; Enoxacin; Female; Fluoroquinolones; Irritants; Mice; Models, Biological; Ofloxacin; Phenotype; Photosensitizing Agents; Quinolones; Skin | 2000 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Studies on the uptake and release of fluoroquinolones by disposable contact lenses.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Contact Lenses, Hydrophilic; Disposable Equipment; Drug Delivery Systems; Fluoroquinolones; Norfloxacin; Ofloxacin; Quinolones | 2001 |
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Limb Buds; Magnesium; Male; Mice; Mice, Inbred Strains; Ofloxacin; Piperazines; Pregnancy; Quinolones | 2002 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2002 |
In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.
Topics: Animals; Anti-Infective Agents; Chromosome Aberrations; Dose-Response Relationship, Drug; Fluoroquinolones; Levofloxacin; Light; Male; Mice; Mice, Hairless; Micronuclei, Chromosome-Defective; Micronucleus Tests; Ofloxacin; Photosensitizing Agents; Quinolones; Skin; Time Factors | 2002 |
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones | 2003 |
[Levofloxacin (Tavanic) in the treatment of corneal ulcers].
Topics: Administration, Oral; Anti-Infective Agents; Corneal Ulcer; Drug Administration Schedule; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Quinolones; Treatment Outcome | 2003 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones | 2003 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
[Simultaneous determination of quinolones in foods by LC/MS/MS].
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fishes; Fluoroquinolones; Food Analysis; Meat; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization | 2004 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
[Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Quinolones | 2005 |
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Quinolones | 2005 |
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Models, Chemical; Models, Statistical; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Quinolones; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Temperature; Time Factors | 2006 |
In vitro activity of lomefloxacin, a new difluorinated quinolone, against urinary bacterial isolates: comparison with enoxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Urinary Tract Infections | 1989 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution | 2006 |
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Rabbits; Staphylococcal Infections; Vitreous Body | 2007 |
Chiral separation of four fluoroquinolone compounds using capillary electrophoresis with hydroxypropyl-beta-cyclodextrin as chiral selector.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Electrophoresis, Capillary; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Molecular Structure; Ofloxacin; Oxazines; Quinolones; Stereoisomerism | 2006 |
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].
Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood | 2006 |
Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.
Topics: Absorption; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Iron Compounds; Kinetics; Minerals; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.
Topics: Biological Transport; Caco-2 Cells; Cell Compartmentation; Dipeptides; Fluoroquinolones; Humans; Intestinal Absorption; Levofloxacin; Membrane Transport Proteins; Ofloxacin; Peptide Transporter 1; Symporters | 2008 |
Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive.
Topics: Buffers; Electrophoresis, Capillary; Fleroxacin; Fluoroquinolones; Gatifloxacin; Nanoparticles; Ofloxacin; Oxazines; Quinolones; Silicon Dioxide | 2009 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures | 2009 |
Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA.
Topics: DNA; Drug Interactions; Drug Synergism; Fluoroquinolones; Norfloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2009 |
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results | 2009 |
[Efficacy of levofloxacin, lomefloxacin and moxifloxacin vs. other fluoroquinolones in experimental plague due to FI+ and FI- strains of Yersinia pestis in Albino mice].
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Mice; Moxifloxacin; Ofloxacin; Plague; Quinolines; Species Specificity; Time Factors; Yersinia pestis | 2009 |
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater.
Topics: Chemical Fractionation; Chemistry, Pharmaceutical; Chromatography, Liquid; Emulsions; Enrofloxacin; Ethane; Fluoroquinolones; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Methanol; Norfloxacin; Ofloxacin; Ultrasonics; Water Pollutants, Chemical; Water Purification | 2011 |
Determination of ofloxacin and lomefloxacin in chicken muscle using molecularly imprinted solid-phase extraction coupled with liquid chromatography.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Fluoroquinolones; Food Contamination; Meat; Molecular Imprinting; Muscles; Ofloxacin; Polymers; Solid Phase Extraction | 2011 |
[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing].
Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Cities; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Soil; Soil Pollutants | 2014 |
Dispersive micro-solid phase extraction using magnetic nanoparticle modified multi-walled carbon nanotubes coupled with surfactant-enhanced spectrofluorimetry for sensitive determination of lomefloxacin and ofloxacin from biological samples.
Topics: Fluoroquinolones; Magnetite Nanoparticles; Nanotubes, Carbon; Ofloxacin; Solid Phase Extraction | 2016 |
[Distribution Characteristics of Fluoroquinolones Antibiotics in Surface Water and Groundwater from Typical Areas in A City].
Topics: Anti-Bacterial Agents; Cities; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Groundwater; Norfloxacin; Ofloxacin; Rivers; Sewage; Water; Water Pollutants, Chemical | 2015 |
[Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis].
Topics: Adsorption; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Norfloxacin; Ofloxacin; Sewage; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Development of a UPLC-MS/MS method for the determination of lomefloxacin in rabbit aqueous humor and its application to a pharmacokinetic study.
Topics: Animals; Aqueous Humor; Calibration; Chromatography, High Pressure Liquid; Fluoroquinolones; Male; Ofloxacin; Ophthalmic Solutions; Rabbits; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors | 2016 |
Escherichia coli adhesive coating as a chiral stationary phase for open tubular capillary electrochromatography enantioseparation.
Topics: Bacterial Adhesion; Buffers; Capillary Electrochromatography; Escherichia coli; Fluoroquinolones; Ofloxacin; Stereoisomerism | 2017 |