ofloxacin has been researched along with levofloxacin in 2095 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.10) | 18.7374 |
| 1990's | 296 (14.13) | 18.2507 |
| 2000's | 1299 (62.00) | 29.6817 |
| 2010's | 482 (23.01) | 24.3611 |
| 2020's | 16 (0.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, DT; Mitscher, LA; Pernet, AG; Sharma, PN; Shen, LL | 1 |
| Dorff, PH; Perni, RB; Rake, JB; Wentland, MP | 1 |
| Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Arpin, C; Ba, BB; Caignard, DH; Forfar-Bares, I; Grellet, J; Guillon, J; Jarry, C; Moreau, S; Quentin, C; Vidaillac, C | 1 |
| Aubry, A; Cambau, E; Jarlier, V; Matrat, S; Petrella, S; Sougakoff, W | 1 |
| Arsène, S; Leclercq, R | 1 |
| Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chhasatia, MR; Gandhi, DS; Patel, MN | 1 |
| Caddick, JM; Gunell, M; Hakanen, AJ; Huovinen, P; Jalava, J; Kotilainen, P; Lilly, AJ; Piddock, LJ; Siitonen, A; Webber, MA | 1 |
| Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E | 1 |
| Martínez, JL; Sánchez, MB | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Blango, MG; Mulvey, MA | 1 |
| Ahn, JH; Bae, IK; Lee, JE; Lee, JJ; Lee, SH; Park, I; Park, KS; Sun, HI; Woo, GJ | 1 |
| Aytemir, MD; Ozçelik, B | 1 |
| Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Anderson, BE; Burda, WN; Cormier, R; Edlinger, J; Harrington, L; Kapolka, R; Kodigepalli, KM; Roma, G; Shaw, LN; Thomas, J; Turos, E | 1 |
| Imai, YN; Oiki, S; Ryu, S | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Zhang, B | 1 |
| Bishai, WR; Duan, G; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
| Bera, S; Mondal, D | 1 |
| Blaskovich, MAT; Pham, TDM; Ziora, ZM | 1 |
| Bishai, WR; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Wang, SS; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
| Bhagwat, S; Bhawsar, S; Deshpande, P; Joshi, S; Patel, M; Yeole, R | 1 |
| Akagashi, K; Aoki, M; Hirose, T; Kumamoto, Y; Miyake, M; Miyao, N; Nishimura, M; Tsukamoto, T; Yanase, M; Yokoo, A | 1 |
| Doi, H; Kurimura, O; Ooishi, A; Tamura, R | 1 |
| Kumazawa, J; Matsumoto, T | 1 |
| Barrett, JF; Foleno, B; Fu, KP; Isaacson, DM; Lafredo, SC; Rosenthale, ME; Tobia, AJ | 1 |
| Chida, T; Hashimoto, S; Inagaki, Y; Nakaya, R | 1 |
| Hukagawa, H; Noga, K | 1 |
| Doi, S; Fujimoto, M; Kinoshita, H; Morimoto, K; Nakatani, S; Ohmori, K; Ohno, K; Sakai, K; Ueda, T; Yamazaki, O | 1 |
| Iwata, Y; Mizuhara, H; Soyama, Y | 1 |
| Araki, H; Cho, N; Fukunaga, K; Ichikawa, K; Kimura, T; Kunii, K; Shimizu, A | 1 |
| Hirayama, H; Matsuda, S; Oh, K | 1 |
| Aoki, N; Hayashi, S; Honma, C; Koda, Y; Nitta, I; Takasawa, T; Usuda, Y; Wakabayashi, N; Watanabe, K | 1 |
| Nakamori, Y; Nakata, K; Nakatani, T; Narui, K; Sugi, H; Tsuboi, E | 1 |
| Hara, K; Iwamoto, M; Kaku, M; Koga, H; Kohno, S; Kusano, S; Maesaki, S; Sakito, O; Sugawara, K; Tanaka, K | 1 |
| Aoki, Y; Ichimiya, G; Kobayashi, Y; Ohnishi, H; Oka, S; Okamura, T; Shimada, K; Tanimura, H; Uenishi, M; Yamamoto, S | 1 |
| Ishihara, H; Ishikawa, M; Ishikawa, S; Mashita, K; Mizuno, A; Shinagawa, N; Suzui, K; Suzuki, T; Taniguchi, M; Yura, J | 1 |
| Abe, Y; Akiyama, H; Arata, J; Kanzaki, H; Katayama, H; Nishihara, O; Shimoe, K; Torigoe, R; Umemura, S; Yamada, T | 1 |
| Chimura, T; Funayama, T; Morisaki, N; Oda, T | 1 |
| Hamaya, O; Kaneko, K; Miyamura, R; Miyata, K; Ono, K; Saiko, Y; Saito, I; Suzuki, A; Yamamoto, T; Yokozawa, M | 1 |
| Ono, K; Saiko, Y; Saito, I; Suzuki, A; Yokozawa, M | 1 |
| Furuhama, K; Hayakawa, I; Osada, Y; Takayama, S | 1 |
| Akahane, K; Furuhama, K; Kato, M; Takayama, S; Yoshida, M | 1 |
| Ashby, R; Fowler, JS; Furuhama, K; Kato, M; Takayama, S; Woolley, AP | 1 |
| Fujikawa, K; Harada, S; Ohura, K; Sasaki, T; Takayama, S; Watanabe, T | 1 |
| Hattori, C; Itoh, S; Matsuura, Y; Shimada, H; Tada, S | 1 |
| Hattori, H; Takayama, S; Wagai, N; Yamaguchi, F | 1 |
| Domon, S; Kajimura, T; Kudo, G; Nomura, M; Takayama, S; Tojo, H; Yamada, M | 1 |
| Akahane, K; Inage, F; Kato, M; Takayama, S; Yoshida, M | 1 |
| Kajimura, T; Nomura, M; Takayama, S; Yamada, M; Yamamura, H | 1 |
| Takayama, S; Wagai, N; Yoshida, M | 1 |
| Akahane, K; Furuhama, K; Takayama, S; Tawara, K | 1 |
| Hirohashi, M; Kasai, Y; Takahashi, M; Takasuna, K; Takayama, S; Tamura, K; Usui, C | 1 |
| Horiba, M; Suzuki, K | 1 |
| Katsukawa, C; Makino, M; Osato, K | 1 |
| Akahane, K; Akaike, N; Imanishi, T | 1 |
| Baltch, AL; Ritz, W; Smith, RP | 1 |
| Dekio, S; Saito, H; Sato, K; Tomioka, H | 1 |
| Kato, M; Takada, S; Takayama, S | 1 |
| Bryson, HM; Davis, R | 1 |
| Geweniger, KH; Isert, D; Iyer, P; Klesel, N; Koletzki, P; Limbert, M; Markus, A; Riess, G; Schramm, H | 1 |
| Cormican, MG; Jones, RN; Runyon, BA | 1 |
| Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C | 1 |
| Citron, DM; Goldstein, EJ; Nesbit, CA | 1 |
| Kaatz, GW; Kang, SL; McGrath, BJ; Rybak, MJ; Seo, SM | 1 |
| Jones, RN; Sutton, LD | 1 |
| Cormican, MG; Jones, RN | 1 |
| Hori, R; Kagimoto, N; Nomura, H; Okumura, K; Tanigawara, Y | 1 |
| Cormican, MG; Jones, RN; Marshall, SA | 1 |
| Morissey, I; Smith, JT | 1 |
| Jin, Y; Mochizuki, K; Ohkubo, S; Okamura, Y; Tanahashi, T; Tanaka, M; Torisaki, M; Yamashita, Y | 1 |
| Akahane, K; Kimura, Y; Kitano, Y; Tsutomi, Y | 1 |
| Kato, M; Takayama, S; Yoshida, M | 1 |
| Parte, AC; Smith, JT | 2 |
| Cherubin, CE; Stratton, CW | 1 |
| Allen, S; Barry, A; Fuchs, P; Hardy, D; Jorgensen, J; McLaughlin, J; Reller, L; Tenover, F | 1 |
| Akahane, K; Kato, M; Takayama, S | 1 |
| Bale, MJ; Erwin, ME; Jones, RN | 1 |
| Cynamon, MH; Klemens, SP; Rogge, MC; Sharpe, CA | 1 |
| Houston, AK; Jones, RN | 1 |
| Irifune, K; Ishida, K; Kaku, M; Mizukane, R; Suyama, N; Takemura, H; Tanaka, H; Tomono, K; Usui, T; Yoshida, R | 1 |
| Bartlett, JA; Chow, AT; Flor, SC; Gallis, HA; Goodwin, SD; Wong, FA | 1 |
| Bodey, GP; Dholakia, N; Ho, DH; LeBlanc, B; Rolston, KV | 1 |
| Kawahara, S; Kitano, Y; Nagare, H | 1 |
| Heifets, L; Mor, N; Vanderkolk, J | 1 |
| Frei, R; Hoban, DJ; Jones, RN; Marco, F; Pignatari, AC; Yamane, N | 1 |
| Saito, A | 1 |
| Aoki, H; Fujisawa, C; Hakusui, H; Kurata, T; Ohshima, Y; Okazaki, O; Tanaka, M | 1 |
| Moroi, R; Sato, E; Yoshida, Y | 1 |
| Barry, AL; Fuchs, PC; Pfaller, MA | 1 |
| Foleno, BD; Fu, KP; Lafredo, SC | 1 |
| Allen, SD; Baker, CN; Barry, AL; Fuchs, PC; Hardy, DJ; Jorgensen, JH; Murray, PR; Tenover, FC | 1 |
| Lentino, JR; Pachucki, CT; Patel, JA | 1 |
| Kato, M; Ogawara, S; Takada, S; Takayama, S | 1 |
| Dhople, AM; Ibanez, MA | 1 |
| Hasegawa, T; Muraoka, I; Nabeshima, T; Nadai, M; Takagi, K; Yamaki, K | 1 |
| Wang, F; Zhang, JD; Zhang, YY; Zhou, L; Zhu, DM | 1 |
| Kawai, T | 1 |
| Miyashita, Y; Nakamori, Y; Nakata, K; Nakatani, I | 1 |
| Odagiri, S | 1 |
| Ida, M; Iwata, M; Nagayama, M; Ogawa, H; Ono, T; Sato, A; Shirai, M; Shirai, T; Suda, T; Yasuda, K | 1 |
| Furukawa, K; Kawakami, K; Kono, H; Nagai, H; Shishido, H | 1 |
| Hayden, MK; Matushek, MG; Trenholme, GM | 1 |
| Andrews, JM; Child, J; Chow, AT; Mortiboy, D; Wise, R | 1 |
| Edelstein, MA; Edelstein, PH; Lehr, KH; Ren, J | 1 |
| Arakawa, M; Hosaka, K; Kudou, Y; Oya, S; Takemoto, A | 1 |
| Allen, SD; Barry, AL; Brown, SD; Fuchs, PC; Jorgensen, JH; Tenover, FC | 1 |
| Barrett, JF; Bernstein, JI; Fernandez, JA; Hilliard, JJ; Krause, HM; Nguyen, V; Ohemeng, KA | 1 |
| Cormican, MG; Erwin, ME; Jones, RN; Marshall, SA | 1 |
| Akahane, K; Kato, M; Nomura, M; Ohkawara, S | 1 |
| Inotsume, N; Inui, KI; Ohtomo, T; Saito, H; Yasuhara, M | 1 |
| Fujimoto, K; Hayashi, T; Osada, T; Sakurai, T; Yamamura, K | 1 |
| Bryskier, A; Devallois, A; Goh, KS; Rastogi, N | 2 |
| Barry, AL; Brown, SD; Fuchs, PC | 4 |
| Kajimura, T; Komatsu, M; Mochizuki, K; Ogata, M; Ohkubo, S; Tanahashi, T; Torisaki, M; Yamashita, Y | 1 |
| Imai, Y; Sano, K; Tokoro, T | 1 |
| Eliopoulos, GM; Moellering, RC; Wennersten, CB | 1 |
| Plouffe, JF | 1 |
| Biedenbach, DJ; Jones, RN | 1 |
| van Ogtrop, ML | 1 |
| Hayakawa, I; Hohmura, M; Hoshino, K; Ishida, H; Kitamura, A; Nishino, T; Sato, K; Tanaka, M | 1 |
| Barry, AL; Brown, SD | 1 |
| Bermudez, LE; Kolonoski, P; Young, LS | 1 |
| Barbara-Burnham, L; Bermudez, LE; Inderlied, CB; Kolonoski, P; Wu, M; Young, LS | 1 |
| Palmer, SM; Rybak, MJ | 1 |
| Fujieda, Y; Ito, T; Nakagawa, T; Yamaoka, K | 1 |
| Peters, G; von Eiff, C | 2 |
| Citron, DM; Claros, MC; Goldstein, EJ; Hunt Gerardo, S | 1 |
| Bornstein, M; Johnson, K; Williams, NA | 1 |
| Damm, D; Lehr, KH; Malerczyk, V; Verho, M | 1 |
| Barrett, JF; Frosco, MB; Kulwich, BA; Licata, L; Melton, JL; Stewart, FP | 1 |
| Hecht, DW; Wexler, HM | 1 |
| Goldstein, EJ | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ; Salvador, J | 1 |
| Domingue, G; Johnson, AP; Speller, DC; Warner, M | 1 |
| Fowler, C; Liao, S; Nayak, RK; Palmer, M | 1 |
| Arvieux, C; Avril, JL; Cartier, F; Jacquelinet, C; Michelet, C; Vu, N | 1 |
| Flynn, CM; Johnson, DM; Jones, RN | 1 |
| Ballesta, S; García, I; Pascual, A; Perea, EJ | 2 |
| Chow, AT; Fish, DN | 1 |
| Bryskier, A; Capper, T; Klugman, KP | 1 |
| Amaratunga, DJ; Barrett, JF; Frosco, MB; Yagel, SK | 1 |
| Inui, K; Ito, T; Takano, M; Yano, I | 1 |
| Barrett, JF; Frosco, M; Goldschmidt, RM; Licata, L; Smith, CE | 1 |
| Appelbaum, PC; Bajaksouzian, S; Jacobs, MR; Visalli, MA | 1 |
| Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV | 2 |
| Barrett, JF; Foleno, BE; Frosco, MB; Smith, CE | 1 |
| Flor, SC; Juzwin, SJ; Wong, FA | 1 |
| Stewart, PS; Suci, PA; Vrany, JD | 1 |
| Ambrose, PG; Nightingale, CH; Owens, RC; Quintiliani, R | 1 |
| Kuriyama, T; Nakagawa, K; Saiki, Y; Yamamoto, E | 1 |
| Chien, SC; Chow, AT; Natarajan, J; Nayak, RK; Rogge, MC; Williams, RR; Wong, FA | 1 |
| Aikawa, N; Denno, R; Fujimoto, M; Hirata, AK; Ishibiki, K; Ishihara, R; Ishikawa, S; Iwai, S; Kinoshita, H; Koide, H; Kunimatsu, M; Manabe, T; Mashita, K; Mizuno, A; Morimoto, K; Mukaiya, M; Ohnishi, H; Ohtsuka, K; Sakaguchi, S; Shinagawa, N; Takuma, K; Tanimura, H; Umemoto, Y; Ushijima, Y; Yura, J | 1 |
| Chimura, T | 2 |
| George, J; Morrissey, I | 1 |
| Maurin, M; Raoult, D | 1 |
| Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H | 1 |
| Takazakura, E; Tsuji, H | 1 |
| Entenza, JM; Glauser, MP; Moreillon, P; Vouillamoz, J | 2 |
| Chien, SC; Chow, AT; Hendrix, CW; Rogge, MC; Williams, RR | 1 |
| Akaki, T; Sato, K; Tomioka, H | 2 |
| Inui, KI; Ito, T; Tanaka, K; Yano, I | 1 |
| Iijima, S; Otsuka, F; Saito, J | 1 |
| Akaki, T; Kawahara, S; Sato, K; Shimizu, T; Tomioka, H | 1 |
| Appelbaum, PC; Jacobs, MR; Visalli, MA | 2 |
| Dunbar, L; File, TM; Kohler, R; Kojak, C; Player, R; Rubin, A; Segreti, J; Williams, RR | 1 |
| Dix, R; Hafkin, B; Hoh, J; Lee, ID; Lee, LJ | 1 |
| Cheung, WK; Chien, SC; Chow, AT; Curtin, C; Fowler, CL; Gisclon, LG; Natarajan, J; Rogge, MC; Williams, RR; Wong, F | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE | 1 |
| Edlund, C; Nord, CE; Sjöstedt, S | 1 |
| Andrews, JM; Brenwald, NP; Cunningham, B; Honeybourne, D; Jevons, G; Wise, R | 1 |
| Curtin, CR; Fowler, CL; Gisclon, LG; Hafkin, B; Natarajan, J; Williams, RR | 1 |
| Ernst, EJ; Ernst, ME; Klepser, ME | 1 |
| Chen, C; Danziger, LH; Martin, SJ; Pendland, SL; Schreckenberger, PC | 1 |
| Jones, RN; Pfaller, MA | 3 |
| Campbell, T; Gentry, LO; Gezon, J; Nichols, RL; Smith, JW; Sokol, P; Williams, RR | 1 |
| Bauernfeind, A | 2 |
| Baltch, AL; Franke, M; Hioe, W; Michelsen, P; Ritz, W; Smith, RP | 1 |
| Fung, CP; Hu, BS; Lau, YJ; Lin, YH; Liu, PY; Shi, ZY | 1 |
| Berman, AL; Chow, AT; Corrado, M; Dornseif, B; Drusano, GL; Fowler, CL; Natarajan, J; Preston, SL; Reichl, V | 1 |
| Au, KF; Chau, CH; Lee, J; Yew, WW | 1 |
| Kahn, J; Mauriz, Y; Ogilvie, P; Thornsberry, C | 1 |
| Tuohy, M; Washington, JA | 1 |
| Arnold, B; Stout, JE; Yu, VL | 1 |
| Itoh, S; Miura, M; Shimada, H | 1 |
| Berning, SE; Huitt, GA; Iseman, MD; Peloquin, CA | 1 |
| Izumi, K; Kawazoe, K; Mikamo, H; Sato, Y; Tamaya, T | 1 |
| Adamantidis, MM; Bordet, R; Caron, JF; Dumotier, BM | 1 |
| Chuck, SK; Jung, R; Martin, SJ; Messick, CR; Meyer, JM; Pendland, SL | 1 |
| Evans, ME; Titlow, WB | 1 |
| Barrett, MS; Jones, RN | 1 |
| Domon, H; Miyazaki, S; Yamaguchi, K; Yoshizumi, S | 1 |
| Callery-D'Amico, SV; Chien, SC; Chow, AT; Fowler, CL; Nayak, R; Williams, RR; Wong, FA | 1 |
| Finegold, SM; Molitoris, D; Molitoris, E; Wexler, HM | 1 |
| Anthony, KE; Fowler, CL; Kim, SS; Kopp, EJ; LoCoco, JM; Sydnor, TA | 1 |
| Kawahara, K; Kitajima, I; Maruyama, I; Nakata, M; Yamakuchi, M | 1 |
| Brookings, E; Gray, B; Nix, S; Robinson, A; Swiatlo, E; Waites, K | 1 |
| Callery-D'Amico, S; Cox, CE; Fowler, CL; Kim, SS; King, W; Klimberg, IW | 1 |
| Berman, AL; Chow, AT; Corrado, M; Dornseif, B; Drusano, GL; Fowler, CL; Natarajan, J; Preston, SL; Reichl, V; Wong, FA | 1 |
| Appelbaum, PC; Jacobs, MR; Lin, G; Spangler, SK | 1 |
| Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE | 1 |
| Chien, SC; Doose, DR; Nayak, RK; Walker, SA; Williams, RR | 1 |
| Jasovich, A; Neto, W; Nicodemo, AC; Robledo, JA | 1 |
| Eskens, JL; Gibbs, RS; McDuffie, RS | 1 |
| Arai, M; Chimura, T; Kawagoe, S; Kunii, K; Matsuo, M; Morizaki, N; Murayama, K; Numazaki, M; Oda, T; Onuma, Y; Saito, N; Saito, T; Sato, F | 1 |
| Ishida, H; Ishida, Y; Kobayashi, H; Kurosaka, Y; Otani, T; Sato, K | 1 |
| Callery-D'Amico, S; Fowler, CL; Kim, SS; Klimberg, IN; Richard, GA | 1 |
| Andrews, JM; Wise, R | 1 |
| Bornitz, F; Hof, H; Kretschmar, M; Nichterlein, T | 1 |
| Catalan, F; Milovanovic, A; Prouteau, C; Soulignac, M | 1 |
| Lamb, HM; Langtry, HD | 1 |
| Hashimoto, Y; Inui, K; Ito, T; Matsuo, Y; Yano, I | 1 |
| Norrby, SR; Petermann, W; Salewski, E; Vetter, N; Willcox, PA | 1 |
| Appelbaum, PC; Clark, CL; Jacobs, MR | 1 |
| Alperstein, P; France, K; Isenberg, HD | 2 |
| Barrett, T; DiPersio, JR; Doern, GV; Jones, RN; Pfaller, MA | 1 |
| Giamarellos-Bourboulis, EJ; Giamarellou, H; Grecka, P; Sambatakou, H | 1 |
| Baltch, AL; Franke, MA; Michelsen, PB; Smith, RP | 1 |
| Akiyama, H; Arata, J; Kanzaki, H; Tada, J; Yamasaki, O | 1 |
| Cevenini, R; Donati, M; Marchetti, F; Rumpianesi, F; Sambri, V | 1 |
| Frick, A; Möller, H; Wirbitzki, E | 1 |
| Anjo, S; Hara, A; Nakamura, M; Sakai, M | 1 |
| Bryskier, A; Labro, MT; Vazifeh, D | 1 |
| Ferraro, MJ; Jorgensen, JH; Swenson, JM; Tenover, FC; Weigel, LM | 1 |
| Aeschlimann, JR; Dresser, LD; Kaatz, GW; Rybak, MJ | 1 |
| Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR | 1 |
| Amicosante, G; De Santis, A; Franceschini, N; Marchetti, F; Perilli, M; Segatore, B; Setacci, D | 1 |
| Amaratunga, D; Barrett, JF; Fernandez, J; Frosco, M; Licata, L | 1 |
| Lacy, MK; Lu, W; Nicolau, DP; Nightingale, CH; Quintiliani, R; Tessier, PR; Xu, X | 1 |
| Adelglass, J; Campbell, T; DeAbate, CA; Fowler, CL; LoCocco, J; McElvaine, P | 1 |
| Inui, K; Okuda, M; Saito, H; Urakami, Y | 1 |
| Sáez-Nieto, JA; Vázquez, JA | 1 |
| Benson, CA; Chirgwin, KD; El-Sadr, WM; Matts, JP; Nelson, ET; Perlman, DC; Sepkowitz, KA; Telzak, EE | 1 |
| Dabernat, H | 1 |
| Holt, HA; MacGowan, AP; Wootton, M | 1 |
| MacGowan, AP; Sunderland, J; Tobin, CM; White, LO | 1 |
| Hashimoto, Y; Inui, K; Ito, T; Masuda, S; Yano, I | 1 |
| Furuya, N; Iwata, M; Matsumoto, T; Mizuiri, S; Tateda, K; Yamaguchi, K | 1 |
| Boyer, E; Chamberland, S; Hoshino, K; Ishida, H; Lee, A; Lee, VJ; Lomovskaya, O; Mistry, A; Warren, MS | 1 |
| Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R | 1 |
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| Chamberland, S; Flamme, EM; Gannon, CL; Ishida, Y; Lee, VJ; Léger, R; Lomovskaya, O; Mathias, KM; Nakayama, K; Ohta, T; Renau, TE; She, MW | 1 |
| Benz, C; Böttcher, S; Hoppe-Tichy, T; Sonntag, HG; von Baum, H | 1 |
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| Cirioni, O; Ghiselli, R; Giacometti, A; Kamysz, W; Kasprzykowski, F; Mackiewicz, Z; Mocchegiani, F; Orlando, F; Paggi, AM; Saba, V; Scalise, G | 1 |
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| Bucsa, C; Farcas, A; Huruba, M; Leucuta, DC; Mogosan, C; Sipos, M | 1 |
| Arvieux, C; Bellissant, E; Comets, E; Fily, F; Foulquier, JB; Huten, D; Jullien, V; Laviolle, B; Lemaitre, F; Petitcollin, A; Polard, JL; Revest, M; Tattevin, P; Tron, C; Verdier, MC | 1 |
| An, D; Chen, Y; Qian, Y; Shi, Y; Tan, X; Wang, X | 1 |
| Liu, F; Qin, X; Wang, B; Wang, G; Weng, L; Zhong, X | 1 |
| Adams, KK; Clarke, LG; Shah, S | 1 |
| Chen, L; Teng, M; Zhang, W; Zhao, L | 1 |
145 review(s) available for ofloxacin and levofloxacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Quinolone antibiotics.
Topics: | 2019 |
Levofloxacin, a new quinolone antibacterial agent. An introductory overview.
Topics: Animals; Anti-Infective Agents; Bacteria; Humans; Levofloxacin; Ofloxacin | 1992 |
Levofloxacin. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacy.
Topics: Administration, Oral; Aging; Bacteria; Bacterial Infections; Biological Availability; Drug Interactions; Female Urogenital Diseases; Half-Life; Humans; Levofloxacin; Male Urogenital Diseases; Microbial Sensitivity Tests; Ofloxacin; Respiratory Tract Infections; Stereoisomerism | 1994 |
[[New antimicrobial agent series XLVII]: levofloxacin].
Topics: Absorption; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Bacterial Infections; Drug Interactions; Female; Humans; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Tissue Distribution | 1994 |
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Safety; Syndrome | 1996 |
The clinical pharmacokinetics of levofloxacin.
Topics: Anti-Infective Agents; Clinical Trials, Phase III as Topic; Drug Interactions; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Ofloxacin | 1997 |
New generations of quinolones: with particular attention to levofloxacin.
Topics: Anti-Infective Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones | 1997 |
Levofloxacin and trovafloxacin: the next generation of fluoroquinolones?
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin | 1997 |
Levofloxacin and sparfloxacin: new quinolone antibiotics.
Topics: Absorption; Anti-Infective Agents; Bronchitis; Drug Interactions; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones; Sinusitis; Skin Diseases; Urinary Tract Infections | 1998 |
Levofloxacin. Its use in infections of the respiratory tract, skin, soft tissues and urinary tract.
Topics: Animals; Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Skin Diseases, Infectious; Soft Tissue Infections; Urinary Tract Infections | 1998 |
New fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Piperazines; Respiratory Tract Infections | 1999 |
[Levofloxacin, in vitro activity].
Topics: Anti-Infective Agents; Cells, Cultured; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1999 |
[Clinical experience of levofloxacin in community acquired pneumonia].
Topics: Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Risk Factors | 1999 |
[Levofloxacin for prevalent infections in primary care medicine].
Topics: Anti-Infective Agents; Bacterial Infections; Community-Acquired Infections; Humans; Levofloxacin; Ofloxacin; Primary Health Care; Respiratory Tract Infections; Urinary Tract Infections | 1999 |
[The safety profile and tolerance of levofloxacin].
Topics: Anti-Infective Agents; Drug Interactions; Levofloxacin; Ofloxacin; Safety | 1999 |
[The present and future of levofloxacin in the treatment of respiratory infections].
Topics: Anti-Infective Agents; Clinical Trials as Topic; Humans; Levofloxacin; Models, Molecular; Ofloxacin; Respiratory Tract Infections; Streptococcus pneumoniae | 1999 |
[Usefulness of levofloxacin in sinusitis].
Topics: Anti-Infective Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Sinusitis | 1999 |
Treatment of tularemia with fluoroquinolones: two cases and review.
Topics: Adult; Anti-Infective Agents; Bacteremia; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tularemia | 1999 |
Pharmacodynamics and pharmacokinetics of levofloxacin.
Topics: Anti-Infective Agents; Area Under Curve; Cost-Benefit Analysis; Cross Infection; Drug Costs; Humans; Levofloxacin; Ofloxacin; Streptococcal Infections; Streptococcus pneumoniae | 2000 |
The use of levofloxacin in the treatment of respiratory tract infection.
Topics: Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Pneumococcal; Respiratory Tract Infections; Streptococcus pneumoniae | 2000 |
Levofloxacin.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Clinical Trials as Topic; Humans; Levofloxacin; Ofloxacin | 1999 |
[Injectable quinolones].
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Humans; Injections, Intravenous; Levofloxacin; Ofloxacin | 2001 |
A risk-benefit assessment of levofloxacin in respiratory, skin and skin structure, and urinary tract infections.
Topics: Animals; Anti-Infective Agents; Drug Resistance, Microbial; Drug-Related Side Effects and Adverse Reactions; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Risk Assessment; Skin Diseases, Bacterial; Urinary Tract Infections | 2001 |
History of quinolones and their side effects.
Topics: Anti-Infective Agents; History, 20th Century; History, 21st Century; Levofloxacin; Ofloxacin; Structure-Activity Relationship | 2001 |
Comparison of side effects of levofloxacin versus other fluoroquinolones.
Topics: Anti-Infective Agents; Cardiovascular System; Dermatitis, Phototoxic; Digestive System; Hepatocytes; Humans; Levofloxacin; Ofloxacin; Seizures; Streptococcus pneumoniae; Tendinopathy; Tendon Injuries | 2001 |
A comparison of side effects of levofloxacin to other agents concerning the ecological and microbiological effects on normal human flora.
Topics: Anti-Infective Agents; Digestive System; Drug Resistance, Microbial; Ecology; Enterococcus; Gastrointestinal Diseases; Humans; Levofloxacin; Ofloxacin; Randomized Controlled Trials as Topic | 2001 |
Latest industry information on the safety profile of levofloxacin in the US.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Clinical Trials as Topic; Drug Approval; Drug Industry; Humans; Levofloxacin; Ofloxacin; Reproducibility of Results; Treatment Outcome; United States; United States Food and Drug Administration | 2001 |
Latest industry information on the safety profile of levofloxacin in Japan.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Central Nervous System; Chemical and Drug Induced Liver Injury; Dermatitis, Phototoxic; Drug Industry; Fluoroquinolones; Heart Diseases; Humans; Japan; Levofloxacin; Naphthyridines; Ofloxacin; Seizures; Substance Withdrawal Syndrome | 2001 |
[Levofloxacin (Tavanic)--a novel quinolone of the III generation. Antimicrobial activity, pharmacokinetics, clinical significance].
Topics: Anti-Infective Agents; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Ofloxacin | 2001 |
Optimal treatment strategies for community-acquired pneumonia: high-risk patients (geriatric and with comorbidity).
Topics: Age Factors; Aged; Anti-Infective Agents; Community-Acquired Infections; Comorbidity; Drug Resistance, Microbial; Female; Health Status Indicators; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia; Practice Guidelines as Topic; Risk Factors | 2001 |
Optimal treatment strategies for acute exacerbations of chronic bronchitis: high-risk patients.
Topics: Anti-Infective Agents; Bronchitis, Chronic; Diagnosis, Differential; Humans; Levofloxacin; Ofloxacin; Randomized Controlled Trials as Topic; Risk Factors | 2001 |
Seizures associated with fluoroquinolones.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Levofloxacin; Magnesium; Ofloxacin; Seizures; Sodium | 2001 |
[The first 'respiration' fluoroquinolone--levofloxacin (Tavanic) in therapy of bacterial infections. Pharmacodynamics principles in optimization of administration regimens].
Topics: Acute Disease; Animals; Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infections; Humans; Levofloxacin; Maxillary Sinusitis; Ofloxacin; Pneumonia, Bacterial; Respiratory Tract Infections; Urinary Tract Infections | 2001 |
[Third and fourth generation fluoroquinolones].
Topics: Administration, Oral; Anti-Infective Agents; Aza Compounds; Belgium; Biological Availability; Drug Monitoring; Drug Resistance; Fluoroquinolones; Gemifloxacin; Humans; Intestinal Absorption; Levofloxacin; Moxifloxacin; Naphthyridines; Ofloxacin; Patient Selection; Pneumococcal Infections; Quinolines; Respiratory Tract Infections; Streptococcus pneumoniae; Time Factors; Treatment Outcome | 2001 |
[Role of levofloxacin in the treatment of urinary tract infections].
Topics: Anti-Infective Agents, Urinary; Female; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Urinary Tract Infections | 2001 |
[Use of levofloxacin in the antibiotic prophylaxis for diagnostic procedures in urology].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Bacteriuria; Biopsy; Comorbidity; Diagnostic Techniques, Urological; Disease Susceptibility; Drug Evaluation; Endoscopy; Equipment Contamination; Humans; Incidence; Levofloxacin; Lithotripsy; Male; Middle Aged; Ofloxacin; Premedication; Prospective Studies; Prostate; Risk Factors; Urinary Catheterization; Urinary Tract Infections | 2002 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
[Update on levofloxacin in the management of acute sinusitis with risk of complications].
Topics: Abscess; Acute Disease; Anti-Infective Agents; Cellulitis; Clinical Trials as Topic; Disease Progression; Haemophilus Infections; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Risk Factors; Sinusitis | 2002 |
[New microbiological data on the susceptibility of Pneumococci to levofloxacin].
Topics: Anti-Infective Agents; Drug Resistance, Microbial; France; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2002 |
Levofloxacin: an updated review of its use in the treatment of bacterial infections.
Topics: Bacterial Infections; Clinical Trials as Topic; Gram-Negative Bacteria; Humans; Levofloxacin; Ofloxacin | 2002 |
[Side effects of fluoroquinolones. Safety and tolerability of levofloxacin in clinical practice].
Topics: Animals; Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin | 2002 |
[Levofloxacin in the treatment of respiratory infections].
Topics: Acute Disease; Anti-Infective Agents; Bronchitis, Chronic; Clinical Trials as Topic; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Respiratory Tract Infections; Sinusitis | 2002 |
Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature.
Topics: Acute Kidney Injury; Aged; Biopsy, Needle; Cefuroxime; Diagnosis, Differential; Drug Therapy, Combination; Escherichia coli Infections; Female; Humans; Inclusion Bodies; Kidney; Kidney Diseases; Levofloxacin; Malacoplakia; Nephritis, Interstitial; Ofloxacin; Urinary Tract Infections | 2003 |
Current and future perspectives for levofloxacin in severe Pseudomonas aeruginosa infections.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2003 |
Bacteremia due to Comamonas species possibly associated with exposure to tropical fish.
Topics: Administration, Oral; Aged; Aged, 80 and over; Animals; Animals, Domestic; Anti-Infective Agents; Bacteremia; Causality; Comamonas; Diagnosis, Differential; Drug Resistance; Environmental Exposure; Fever; Fish Diseases; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pharyngitis; Tomography, X-Ray Computed; Treatment Outcome; Zoonoses | 2003 |
Levofloxacin: a review of its use in the treatment of bacterial infections in the United States.
Topics: Anti-Infective Agents; Area Under Curve; Bacterial Infections; Biological Availability; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Humans; Intestinal Absorption; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Randomized Controlled Trials as Topic; Tissue Distribution | 2003 |
Fluoroquinolone resistance in ophthalmology and the potential role for newer ophthalmic fluoroquinolones.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Drug Resistance, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmology; Quinolines | 2004 |
Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature.
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Appendicitis; Humans; Levofloxacin; Male; Ofloxacin; Rupture | 2004 |
[Antimicrobial effect of levofloxacin].
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Stereoisomerism | 2003 |
Levofloxacin, a broad spectrum anti-infective: from Streptococcus pneumoniae to Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Humans; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Sensitivity and Specificity; Streptococcus pneumoniae | 2004 |
Levofloxacin PK/PD: from sequential therapy model to high dosage for critical patients.
Topics: Administration, Oral; Anti-Infective Agents; Area Under Curve; Biological Availability; Case-Control Studies; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Maximum Tolerated Dose; Ofloxacin; Pneumonia, Bacterial; Reference Values; Respiratory Tract Infections | 2004 |
Role of levofloxacin in the treatment of lower respiratory tract infections (LRTIs).
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoroquinolones; Follow-Up Studies; Humans; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Treatment Outcome | 2004 |
Levofloxacin in the treatment of urinary tract infections and prostatitis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2004 |
Comparative antimicrobial susceptibility of respiratory tract pathogens.
Topics: Asia, Eastern; Bacterial Infections; Drug Resistance, Microbial; Humans; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Respiratory Tract Diseases; Streptococcus pneumoniae; Sulfamethoxazole; Trimethoprim | 2004 |
Clinical applications of levofloxacin for severe infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Epithelium; Humans; Infections; Levofloxacin; Lung; Ofloxacin | 2004 |
New insights in the treatment by levofloxacin.
Topics: Anti-Infective Agents; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Guidelines as Topic; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial | 2004 |
Levofloxacin: update and perspectives on one of the original 'respiratory quinolones'.
Topics: Animals; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Quinolones; Respiratory Tract Infections; Staphylococcal Skin Infections | 2003 |
[New fluoroquinolones: levofloxacin, moxifloxacin and gatifloxacin].
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Pneumonia; Quinolines; Respiratory Tract Infections | 2004 |
Acute rhabdomyolysis associated with ofloxacin/levofloxacin therapy.
Topics: Adult; Anti-Bacterial Agents; Creatine Kinase; Humans; Levofloxacin; Male; Ofloxacin; Rhabdomyolysis | 2005 |
[Efficacy and safety of levofloxacin in low respiratory tract infection].
Topics: Anti-Bacterial Agents; Central Nervous System Diseases; Clinical Trials as Topic; Dermatitis, Atopic; Gastrointestinal Diseases; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Respiratory Tract Infections; Streptococcus pneumoniae | 2004 |
[Levofloxacin (Tavanic) and therapy of urogenital infections].
Topics: Animals; Female; Humans; Levofloxacin; Male; Ofloxacin; Urinary Tract Infections | 2004 |
[Levofloxacin: role and place in the treatment of infections of the lower respiratory tracts].
Topics: Anti-Bacterial Agents; Bacterial Infections; Central Nervous System; Drug Resistance, Bacterial; Humans; Levofloxacin; Musculoskeletal System; Ofloxacin; Respiratory System; Respiratory Tract Infections | 2004 |
Quinolones for treatment of nosocomial pneumonia: a meta-analysis.
Topics: Anti-Infective Agents; Cilastatin; Ciprofloxacin; Cross Infection; Humans; Imipenem; Levofloxacin; Meta-Analysis as Topic; Ofloxacin; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic | 2005 |
[Modern fluoroquinolones (ciprofoxacin, levofloxacin) and the treatment of skin and soft tissue infections].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Central Nervous System Diseases; Ciprofloxacin; Gastrointestinal Diseases; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Skin Diseases; Skin Diseases, Bacterial; Soft Tissue Infections; Urea | 2004 |
A review of Streptococcus pneumoniae infection treatment failures associated with fluoroquinolone resistance.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Treatment Failure | 2005 |
Current management of acute bacterial rhinosinusitis and the role of moxifloxacin.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Levofloxacin; Meta-Analysis as Topic; Moxifloxacin; Ofloxacin; Practice Guidelines as Topic; Quinolines; Rhinitis; Sinusitis; Streptococcus pneumoniae | 2005 |
L. micdadei PVE successfully treated with levofloxacin/valve replacement: case report and review of the literature.
Topics: Anti-Bacterial Agents; Bioprosthesis; Device Removal; Endocarditis, Bacterial; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Legionella; Legionellosis; Levofloxacin; Male; Middle Aged; Ofloxacin; Prosthesis-Related Infections; Radiation Injuries; Reoperation; Treatment Outcome | 2005 |
Eradication of Helicobacter pylori: recent advances in treatment.
Topics: Drug Resistance, Bacterial; Furazolidone; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Patient Compliance; Rifabutin; Time Factors; Treatment Failure | 2005 |
Fluoroquinolones for treating tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2005 |
[Levofloxacin (oftaquix) a fluoroquinolone of a new generation in prevention of the postoperative endophthalmitis following uncomplicated cataract surgery--the study of the European Society of Cataract and Refractive Surgeons (ESCRS)].
Topics: Administration, Topical; Anti-Bacterial Agents; Cefuroxime; Endophthalmitis; Europe; Humans; Injections; Levofloxacin; Multicenter Studies as Topic; Ofloxacin; Phacoemulsification; Poland; Postoperative Complications; Randomized Controlled Trials as Topic; Treatment Outcome | 2005 |
Systematic review and meta-analysis: levofloxacin-based rescue regimens after Helicobacter pylori treatment failure.
Topics: Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Treatment Failure | 2006 |
Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Gastritis; Helicobacter Infections; Humans; Levofloxacin; Metronidazole; Ofloxacin; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Tetracycline | 2006 |
Value of short-course antimicrobial therapy in community-acquired pneumonia.
Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Clinical Trials, Phase III as Topic; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Microspheres; Ofloxacin; Pneumonia; Time Factors; Treatment Outcome | 2005 |
Acute exacerbation of chronic bronchitis: expanding short-course therapy.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Azithromycin; Bronchitis; Clinical Trials as Topic; Confidence Intervals; Double-Blind Method; Drug Administration Schedule; Humans; Levofloxacin; Microspheres; Middle Aged; Ofloxacin; Severity of Illness Index; Treatment Outcome | 2005 |
[Pathogenesis, diagnosis and therapy of Legionella infections].
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Antigens, Bacterial; Aza Compounds; Azithromycin; Ciprofloxacin; Diagnosis, Differential; DNA, Bacterial; Fluoroquinolones; Humans; Incidence; Legionella; Legionella pneumophila; Legionellosis; Legionnaires' Disease; Levofloxacin; Moxifloxacin; Ofloxacin; Polymerase Chain Reaction; Quinolines; Serotyping; Virulence | 2006 |
Bilateral plantar tendinitis during levofloxacin therapy.
Topics: Anti-Bacterial Agents; Female; Foot Diseases; Humans; Levofloxacin; Middle Aged; Ofloxacin; Tendinopathy | 2006 |
Clinical experience in the management of community-acquired pneumonia: lessons from the use of fluoroquinolones.
Topics: Adult; Anti-Bacterial Agents; Clinical Trials as Topic; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2006 |
Legionella: macrolides or quinolones?
Topics: Animals; Anti-Infective Agents; Azithromycin; Clinical Trials as Topic; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2006 |
Levofloxacin in the treatment of ventilator-associated pneumonia.
Topics: Anti-Infective Agents; Cross Infection; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Respiration, Artificial | 2006 |
Pneumonia due to Pseudomonas aeruginosa: the levofloxacin clinical trials experience.
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Community-Acquired Infections; Cross Infection; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Assessment; Risk Factors; Treatment Outcome | 2006 |
[Levofloxacin nowadays].
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin | 2006 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
Respiratory tract infections: at-risk patients, who are they? Implications for their management with levofloxacin.
Topics: Anti-Bacterial Agents; Bronchitis, Chronic; Community-Acquired Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Risk Factors | 2006 |
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciprofloxacin; Decision Making; Drug Resistance; Enterocolitis, Pseudomembranous; Gram-Positive Bacterial Infections; Humans; Leukemia; Levofloxacin; Lymphoma; Neoplasms; Neutropenia; Ofloxacin | 2006 |
Comparison of the adverse event profiles of levofloxacin 500 mg and 750 mg in clinical trials for the treatment of respiratory infections.
Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections | 2006 |
Research review and update: IQUIX (levofloxacin 1.5%).
Topics: Animals; Anti-Bacterial Agents; Bacteria; DNA, Bacterial; Eye Infections, Bacterial; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Tears; Treatment Outcome | 2006 |
Levofloxacin for the treatment of community-acquired pneumonia.
Topics: Community-Acquired Infections; Humans; Levofloxacin; Ofloxacin; Pneumonia | 2006 |
[Levofloxacin and other antibacterial drugs].
Topics: Anti-Bacterial Agents; Bacterial Infections; Dermatitis; Dosage Forms; Humans; Levofloxacin; Ofloxacin; Otitis Media; Respiratory Tract Infections; Sinusitis; Urinary Tract Infections | 2006 |
Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Cephalosporins; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Urinary Tract Infections | 2007 |
[Treatment for Helicobacter pylori: current criteria].
Topics: Alkylating Agents; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Helicobacter Infections; Helicobacter pylori; Humans; Italy; Levofloxacin; Metronidazole; Ofloxacin; Practice Guidelines as Topic; Proton Pump Inhibitors; Quinolones; Tinidazole; Treatment Outcome | 2007 |
Achilles tendon rupture associated with combination therapy of levofloxacin and steroid in four patients and a review of the literature.
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Casts, Surgical; Female; Follow-Up Studies; Glucocorticoids; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Physical Therapy Modalities; Prednisolone; Pulmonary Disease, Chronic Obstructive; Rupture, Spontaneous; Walkers | 2007 |
Fluoroquinolones for treating tuberculosis.
Topics: Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2008 |
Levofloxacin : a review of its use as a high-dose, short-course treatment for bacterial infection.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Community-Acquired Infections; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Pneumonia | 2008 |
Interactions between warfarin and three commonly prescribed fluoroquinolones.
Topics: Aza Compounds; Ciprofloxacin; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Fluoroquinolones; Humans; International Normalized Ratio; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Warfarin | 2008 |
Levofloxacin resistant Escherichia coli sepsis following an ultrasound-guided transrectal prostate biopsy: report of four cases and review of the literature.
Topics: Aged; Anti-Bacterial Agents; Biopsy; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate; Rectum; Sepsis; Ultrasonography | 2008 |
Levofloxacin.
Topics: Animals; Antitubercular Agents; Humans; Levofloxacin; Ofloxacin; Treatment Outcome; Tuberculosis | 2008 |
Targeted drug delivery to bone: pharmacokinetic and pharmacological properties of acidic oligopeptide-tagged drugs.
Topics: Acids; Alkaline Phosphatase; Animals; Bone and Bones; Drug Delivery Systems; Estradiol; Humans; Levofloxacin; Ofloxacin; Oligopeptides; Pharmaceutical Preparations | 2008 |
Review of third-and fourth-generation fluoroquinolones in ophthalmology: in-vitro and in-vivo efficacy.
Topics: Administration, Topical; Anti-Bacterial Agents; Aza Compounds; Endophthalmitis; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Ophthalmology; Quinolines | 2008 |
[The new aspects of the eradication of Helicobacter pylori and the importance of bacterial resistance].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Drug Administration Schedule; Drug Resistance, Bacterial; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Patient Compliance; Proton Pump Inhibitors; Risk Factors; Salvage Therapy; Treatment Failure | 2008 |
[Effectiveness and safety of proton pump inhibitor and levofloxacin based first-line triple therapy in the eradication of Helicobacter pylori: a meta-analysis].
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Proton Pump Inhibitors | 2008 |
[Present positioning of levofloxacin in chemotherapy of bacterial infections].
Topics: Anti-Bacterial Agents; Bacterial Infections; Humans; Levofloxacin; Ofloxacin | 2008 |
[Present aspects and prospects of levofloxacin use in therapy of nosocomial pneumonia].
Topics: Anti-Bacterial Agents; Cross Infection; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial | 2008 |
[Clinical positioning of levofloxacin in the treatment of nosocomial pneumonia].
Topics: Anti-Bacterial Agents; Cross Infection; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial | 2008 |
[Levofloxacin in complex therapy of patients with skin and soft tissue infections].
Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Ofloxacin; Skin Diseases, Bacterial; Soft Tissue Infections | 2008 |
Efficacy of fluoroquinolones against pathogenic oral bacteria.
Topics: Aza Compounds; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Mouth Diseases; Moxifloxacin; Ofloxacin; Oral Medicine; Quinolines | 2009 |
Levofloxacin 0.5% ophthalmic solution: a review of its use in the treatment of external ocular infections and in intraocular surgery.
Topics: Anti-Bacterial Agents; Conjunctivitis; Drug Resistance, Bacterial; Eye Infections; Humans; Levofloxacin; Ofloxacin; Ophthalmologic Surgical Procedures; Postoperative Complications; Product Surveillance, Postmarketing | 2009 |
Seizures associated with levofloxacin: case presentation and literature review.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cytochrome P-450 CYP1A2; Dopamine Antagonists; Drug Administration Schedule; Drug Synergism; Female; Humans; Klebsiella Infections; Levofloxacin; Male; Metoclopramide; Mianserin; Middle Aged; Mirtazapine; Ofloxacin; Phosphodiesterase Inhibitors; Seizures; Theophylline | 2009 |
An update on Legionella.
Topics: Anti-Bacterial Agents; Antigens, Bacterial; Azithromycin; Community-Acquired Infections; Cross Infection; Germany; Humans; Incidence; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Ofloxacin; United States | 2010 |
[Efficacy of moxifloxacin in treating bacterial conjunctivitis: a meta-analysis].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Conjunctivitis, Bacterial; Double-Blind Method; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Moxifloxacin; Odds Ratio; Ofloxacin; Ophthalmic Solutions; Patient Dropouts; Placebos; Quinolines; Randomized Controlled Trials as Topic; Remission Induction; Risk Factors; Treatment Failure; Treatment Outcome | 2010 |
Helicobacter pylori eradication therapy.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; Drug Resistance, Bacterial; Guidelines as Topic; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Proton Pump Inhibitors; Ranitidine; Tetracycline; Treatment Failure; Treatment Outcome | 2010 |
Safety profile of the fluoroquinolones: focus on levofloxacin.
Topics: Adult; Aged, 80 and over; Anti-Bacterial Agents; Cardiovascular Diseases; Central Nervous System Diseases; Child; Dermatitis, Phototoxic; Drug Hypersensitivity; Enterocolitis, Pseudomembranous; Glucose; Humans; Levofloxacin; Ofloxacin; Skin Diseases | 2010 |
[PK/PD profile and post-marketing surveillance of levofloxacin].
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cohort Studies; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Kidney; Levofloxacin; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Ofloxacin; Product Surveillance, Postmarketing; Respiratory Tract Infections; Spondylitis | 2009 |
[Therapeutic experience with levofloxacin in pneumonia and COPD].
Topics: Algorithms; Anti-Bacterial Agents; Clinical Trials as Topic; Community-Acquired Infections; Cross Infection; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Levofloxacin; Multicenter Studies as Topic; Ofloxacin; Pneumonia, Bacterial; Pulmonary Disease, Chronic Obstructive; Recurrence; Treatment Outcome | 2009 |
[From cystitis to bacterial prostatitis: experience with levofloxacin].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cystitis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Multicenter Studies as Topic; Ofloxacin; Practice Guidelines as Topic; Prostatitis; Pyelonephritis; Randomized Controlled Trials as Topic; Risk Factors; Urethritis; Urinary Tract Infections | 2009 |
Levofloxacin in the treatment of community-acquired pneumonia.
Topics: Aged; Anti-Bacterial Agents; Clinical Trials as Topic; Community-Acquired Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Bacterial; Treatment Outcome | 2010 |
Relapsing Legionella pneumophila cellulitis: a case report and review of the literature.
Topics: Aged; Anti-Bacterial Agents; Azithromycin; Cellulitis; Fatal Outcome; Female; Humans; Immunocompromised Host; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Ofloxacin; Recurrence | 2010 |
Rapid assays for fluoroquinolone resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis.
Topics: Antitubercular Agents; Aza Compounds; Bacterial Proteins; DNA Gyrase; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Genotype; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Sensitivity and Specificity; Tuberculosis, Multidrug-Resistant | 2010 |
Advantages of Moxifloxacin and Levofloxacin-based triple therapy for second-line treatments of persistent Helicobacter pylori infection: a meta analysis.
Topics: Anti-Infective Agents; Aza Compounds; Bismuth; Clarithromycin; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Proton Pump Inhibitors; Quinolines; Randomized Controlled Trials as Topic; Recurrence; Retreatment | 2010 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
Levofloxacin-induced radiation recall dermatitis: a case report and a review of the literature.
Topics: Anti-Bacterial Agents; Breast Neoplasms; Carcinoma, Lobular; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Radiodermatitis; Radiotherapy, Adjuvant; Respiratory Tract Infections | 2010 |
Fluoroquinolones in the management of community-acquired pneumonia in primary care.
Topics: Ambulatory Care; Anti-Bacterial Agents; Aza Compounds; Clinical Trials as Topic; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumonia, Bacterial; Primary Health Care; Quinolines; Streptococcus pneumoniae | 2010 |
[Pulmonary mycobacteriosis caused by Mycobacterium peregrinum in a young, healthy man].
Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2010 |
Pseudomembranous colitis complicating ulcerative colitis.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colitis, Ulcerative; Colonoscopy; Enterocolitis, Pseudomembranous; Female; Humans; Levofloxacin; Ofloxacin; Tomography, X-Ray Computed | 2010 |
[Current perspective of the resistance of Helicobacter pylori strains to antimicrobial drugs].
Topics: Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Proton Pump Inhibitors | 2010 |
Levofloxacin revisited.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Gastrointestinal Diseases; Humans; Levofloxacin; Ofloxacin; Stevens-Johnson Syndrome | 2011 |
[Current value of quinolones in Helicobacter pylori therapy].
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2011 |
A new look at anti-Helicobacter pylori therapy.
Topics: Amoxicillin; Anti-Infective Agents; Bismuth; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Tetracycline | 2011 |
Legionella micdadei prosthetic valve endocarditis complicated by brain abscess: case report and review of the literature.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteriological Techniques; Brain; Brain Abscess; Echocardiography; Endocarditis, Bacterial; Endocardium; Female; Humans; Legionella; Legionellosis; Levofloxacin; Magnetic Resonance Imaging; Male; Middle Aged; Ofloxacin; Prosthesis-Related Infections; Radiography | 2012 |
Levofloxacin for the treatment of respiratory tract infections.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Treatment Outcome | 2012 |
Severe levofloxacin-induced hypoglycaemia: a case report and literature review.
Topics: Aged; Anti-Bacterial Agents; Catheter-Related Infections; Drug Therapy, Combination; Enterococcus; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Hypoglycemia; Immunocompromised Host; Kidney Failure, Chronic; Levofloxacin; Male; Ofloxacin; Renal Dialysis; Sepsis; Stenotrophomonas maltophilia; Trimethoprim, Sulfamethoxazole Drug Combination | 2012 |
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: III. fluoroquinolones.
Topics: Administration, Oral; Anti-Bacterial Agents; Ciprofloxacin; Cystic Fibrosis; Disease Progression; Drug Administration Schedule; Humans; Injections, Intravenous; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2013 |
[Helicobacter pylori - 2012].
Topics: Algorithms; Antacids; Anti-Bacterial Agents; Bismuth; Clarithromycin; Drug Resistance, Microbial; Drug Therapy, Combination; Emigrants and Immigrants; Endoscopy, Gastrointestinal; Europe; Helicobacter Infections; Helicobacter pylori; Humans; Hungary; In Situ Hybridization, Fluorescence; Levofloxacin; Ofloxacin; Peptic Ulcer; Polymerase Chain Reaction; Stomach Neoplasms | 2012 |
Modified sequential therapy regimens for Helicobacter pylori eradication: a systematic review.
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Tetracycline; Treatment Outcome | 2013 |
Levofloxacin/amoxicillin-based schemes vs quadruple therapy for Helicobacter pylori eradication in second-line.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Chi-Square Distribution; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Odds Ratio; Ofloxacin; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome | 2012 |
MP-376 (Aeroquin) for chronic Pseudomonas aeruginosa infections.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Chronic Disease; Clinical Trials as Topic; Drug Discovery; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Treatment Outcome | 2013 |
A review of rescue regimens after clarithromycin-containing triple therapy failure (for Helicobacter pylori eradication).
Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Clarithromycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Proton Pump Inhibitors; Treatment Failure | 2013 |
Fluoroquinolones for treating tuberculosis (presumed drug-sensitive).
Topics: Antitubercular Agents; Ciprofloxacin; Drug Substitution; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2013 |
Second and third line treatment options for Helicobacter pylori eradication.
Topics: Anti-Bacterial Agents; Bismuth; Drug Resistance, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Moxifloxacin; Ofloxacin; Rifabutin; Rifamycins; Rifaximin; Salvage Therapy; Virulence Factors | 2014 |
Fluoroquinolones for the treatment of tuberculosis in children.
Topics: Age Factors; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Risk Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2015 |
Fluoroquinolone-Associated Tendinopathy: Does Levofloxacin Pose the Greatest Risk?
Topics: Animals; Anti-Bacterial Agents; Disease Management; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Risk Factors; Tendinopathy | 2016 |
Alternative pre-approved and novel therapies for the treatment of anthrax.
Topics: Alpha-Globulins; Anthrax; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Bacterial; Antitoxins; Bacillus anthracis; Bacterial Toxins; Daunorubicin; DNA Helicases; Doxorubicin; Drug Discovery; Fluoroquinolones; Humans; Interferon Inducers; Levofloxacin; Linezolid; Moxifloxacin; Ofloxacin; Polyketides; Serine Proteinase Inhibitors; Tilorone; Virulence | 2016 |
Quinolone-induced psychosis: an updated review.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Delirium; Humans; Levofloxacin; Ofloxacin; Psychoses, Substance-Induced; Quinolones | 2020 |
374 trial(s) available for ofloxacin and levofloxacin
| Article | Year |
|---|---|
[Clinical efficacy of levofloxacin (LVFX) single-dose therapy in female acute uncomplicated cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Cystitis; Escherichia coli; Female; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin | 1992 |
Pharmacokinetics and safety of levofloxacin in patients with human immunodeficiency virus infection.
Topics: Absorption; Adolescent; Adult; Chromatography, High Pressure Liquid; Double-Blind Method; Half-Life; HIV Infections; Humans; Levofloxacin; Male; Ofloxacin; Tissue Distribution | 1994 |
Effects of traditional Chinese medicines on pharmacokinetics of levofloxacin.
Topics: Adult; Anti-Infective Agents; Biological Availability; Cross-Over Studies; Drugs, Chinese Herbal; Humans; Levofloxacin; Male; Ofloxacin; Protein Binding | 1995 |
Clinical evaluation of levofloxacin 200 mg 3 times daily in the treatment of bacterial lower respiratory tract infections.
Topics: Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections; Sputum | 1995 |
Levofloxacin: penetration into sputum and once-daily treatment of respiratory tract infections.
Topics: Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections; Sputum; Treatment Outcome | 1995 |
Clinical efficacy of levofloxacin in elderly patients with respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections | 1995 |
Oral levofloxacin 600 mg and 300 mg daily doses in difficult-to-treat respiratory infections.
Topics: Adult; Aged; Anti-Infective Agents; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections | 1995 |
Open-label crossover study to determine pharmacokinetics and penetration of two dose regimens of levofloxacin into inflammatory fluid.
Topics: Adolescent; Adult; Anti-Infective Agents; Cantharidin; Cross-Over Studies; Drug Administration Schedule; Exudates and Transudates; Half-Life; Humans; Inflammation; Levofloxacin; Male; Middle Aged; Ofloxacin | 1995 |
Pharmacokinetics of levofloxacin in comparison to the racemic mixture of ofloxacin in man.
Topics: Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Levofloxacin; Male; Ofloxacin; Regression Analysis; Stereoisomerism | 1996 |
Absence of an effect of levofloxacin on warfarin pharmacokinetics and anticoagulation in male volunteers.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Anticoagulants; Blood Coagulation; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Humans; Levofloxacin; Liver; Male; Ofloxacin; Warfarin | 1996 |
Absence of age and gender effects on the pharmacokinetics of a single 500-milligram oral dose of levofloxacin in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Reference Values; Sex Characteristics | 1997 |
Pharmacokinetics and safety of oral levofloxacin in human immunodeficiency virus-infected individuals receiving concomitant zidovudine.
Topics: Adult; Anti-HIV Agents; Anti-Infective Agents; Double-Blind Method; Drug Interactions; HIV Infections; Humans; Levofloxacin; Male; Ofloxacin; Zidovudine | 1997 |
A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prodrugs; Prospective Studies; Treatment Outcome | 1997 |
Effects of food and sucralfate on a single oral dose of 500 milligrams of levofloxacin in healthy subjects.
Topics: Adolescent; Adult; Anti-Infective Agents; Anti-Ulcer Agents; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Food-Drug Interactions; Half-Life; Humans; Levofloxacin; Male; Ofloxacin; Reference Values; Spectrophotometry, Ultraviolet; Sucralfate | 1997 |
Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Double-Blind Method; Half-Life; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Spectrophotometry, Ultraviolet | 1997 |
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis | 1997 |
Absence of a pharmacokinetic interaction between intravenous theophylline and orally administered levofloxacin.
Topics: Adult; Anti-Infective Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Half-Life; Humans; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Theophylline | 1997 |
Multicenter, randomized study comparing levofloxacin and ciprofloxacin for uncomplicated skin and skin structure infections.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Skin Diseases, Infectious; Treatment Outcome | 1997 |
Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials.
Topics: Adult; Anti-Infective Agents; Area Under Curve; Bacterial Infections; Bayes Theorem; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Levofloxacin; Logistic Models; Male; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Prospective Studies; Respiratory Tract Infections; Skin Diseases, Bacterial; Urinary Tract Infections | 1998 |
Double-blind evaluation of the safety and pharmacokinetics of multiple oral once-daily 750-milligram and 1-gram doses of levofloxacin in healthy volunteers.
Topics: Adolescent; Adult; Anti-Infective Agents; Area Under Curve; Double-Blind Method; Half-Life; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 1998 |
Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Exudates and Transudates; Female; Haemophilus influenzae; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Ofloxacin; Prospective Studies; Sinusitis; Staphylococcus aureus; Streptococcus pneumoniae | 1998 |
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Urinary Tract Infections | 1998 |
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
Levofloxacin does not alter cyclosporine disposition.
Topics: Adult; Cross-Over Studies; Cyclosporine; Double-Blind Method; Drug Interactions; Female; Humans; Immunosuppressive Agents; Levofloxacin; Male; Ofloxacin | 1998 |
A multicentre, double-blind, randomised study comparing the efficacy and safety of oral levofloxacin versus ciprofloxacin in the treatment of uncomplicated skin and skin structure infections.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Skin Diseases, Bacterial; Staphylococcal Infections; Streptococcal Infections; Streptococcus pyogenes; Treatment Outcome | 1998 |
Levofloxacin versus ciprofloxacin versus lomefloxacin in acute pyelonephritis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis | 1998 |
A comparative study of levofloxacin and ceftriaxone in the treatment of hospitalized patients with pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hospitalization; Humans; International Cooperation; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Treatment Outcome | 1998 |
Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin.
Topics: Absorption; Administration, Oral; Anti-Infective Agents; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chemical Phenomena; Chemistry, Physical; Cross-Over Studies; Humans; Hypoglycemic Agents; Levofloxacin; Ofloxacin; Penicillin V; Penicillins; Solubility; Sulfonylurea Compounds | 1998 |
Comparison of the effectiveness of levofloxacin and amoxicillin-clavulanate for the treatment of acute sinusitis in adults.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Sinusitis; Treatment Outcome; Vaginitis | 1999 |
Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chronic Disease; Double-Blind Method; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Middle Aged; Ofloxacin; Treatment Outcome | 1999 |
Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Sinusitis; Treatment Outcome | 1998 |
Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: the relationship with in-vitro activity.
Topics: Aged; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chronic Disease; Double-Blind Method; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Streptococcus pneumoniae; Treatment Outcome | 1999 |
A randomized, crossover design study of the pharmacology of extended-spectrum fluoroquinolones for pneumococcal infections.
Topics: Adult; Anti-Infective Agents; Cross-Over Studies; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Prodrugs; Streptococcus pneumoniae | 1999 |
Pharmacokinetics and safety of high-dose and extended-interval regimens of levofloxacin in human immunodeficiency virus-infected patients.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; HIV Infections; Humans; Intestinal Absorption; Levofloxacin; Male; Ofloxacin | 1999 |
[Effects of levofloxacin once-a-day therapy on uterine cervicitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Chlamydia Infections; Drug Administration Schedule; Female; Humans; Interleukin-6; Interleukin-8; Levofloxacin; Middle Aged; Mucus; Ofloxacin; Uterine Cervicitis | 1999 |
Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Levofloxacin; Middle Aged; Ofloxacin; Protease Inhibitors; Sepsis; Thienamycins | 1999 |
A comparative study on the efficacy of levofloxacin and ceftazidime in acute exacerbation of bronchiectasis.
Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Bronchiectasis; Ceftazidime; Cephalosporins; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies | 1999 |
[Levofloxacin in the treatment of community-acquired pneumococcal pneumonia].
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Clavulanic Acid; Community-Acquired Infections; Drug Therapy, Combination; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal | 1999 |
Aqueous and vitreous penetration of levofloxacin after oral administration.
Topics: Administration, Oral; Anti-Infective Agents; Aqueous Humor; Bacteria; Biological Availability; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Tablets; Tissue Distribution; Vitrectomy; Vitreous Body | 1999 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones | 2000 |
Pharmacokinetics of levofloxacin in healthy Thai male volunteers.
Topics: Anti-Infective Agents; Cross-Over Studies; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin | 1999 |
A controlled trial of a critical pathway for treatment of community-acquired pneumonia. CAPITAL Study Investigators. Community-Acquired Pneumonia Intervention Trial Assessing Levofloxacin.
Topics: Aged; Anti-Infective Agents; Canada; Community-Acquired Infections; Critical Pathways; Female; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Outcome Assessment, Health Care; Pneumonia; Sickness Impact Profile; Statistics, Nonparametric | 2000 |
[Efficacy of single-dose therapy with levofloxacin for acute cystitis: comparison to three-day therapy].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Child; Cystitis; Drug Administration Schedule; Escherichia coli Infections; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Treatment Outcome | 2000 |
Economic assessment of the community-acquired pneumonia intervention trial employing levofloxacin.
Topics: Aged; Anti-Infective Agents; Canada; Cluster Analysis; Community-Acquired Infections; Critical Pathways; Delivery of Health Care; Female; Humans; Length of Stay; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Severity of Illness Index | 2000 |
Photoreaction potential of orally administered levofloxacin in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Dermatitis, Phototoxic; Double-Blind Method; Female; Humans; Levofloxacin; Male; Ofloxacin; Photochemistry; Ultraviolet Rays | 2000 |
Complicating risk factors for pyelonephritis after extracorporeal shock wave lithotripsy.
Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Humans; Kidney Calculi; Levofloxacin; Lithotripsy; Middle Aged; Multivariate Analysis; Ofloxacin; Postoperative Complications; Predictive Value of Tests; Pyelonephritis; Risk Factors; Sex Distribution | 2000 |
A population pharmacokinetic analysis of the penetration of the prostate by levofloxacin.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Demography; Humans; Levofloxacin; Male; Middle Aged; Monte Carlo Method; Ofloxacin; Prostate; Prostatitis | 2000 |
An economic evaluation of levofloxacin versus cefuroxime axetil in the outpatient treatment of adults with community-acquired pneumonia.
Topics: Adult; Aged; Ambulatory Care; Anti-Infective Agents; Cefuroxime; Cephalosporins; Drug Costs; Evaluation Studies as Topic; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies | 2000 |
Efficacy of two one-week rabeprazole/levofloxacin-based triple therapies for Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studies; Gastric Acid; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Penicillins; Prospective Studies; Rabeprazole; Tinidazole | 2000 |
Levofloxacin pharmacokinetics and serum bactericidal activities against five enterobacterial species.
Topics: Adult; Anti-Infective Agents; Enterobacteriaceae; Female; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Serum Bactericidal Test | 2000 |
[Tolerability and safety of levofloxacinin long-term treatment].
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Female; Humans; Levofloxacin; Long-Term Care; Male; Middle Aged; Ofloxacin; Osteomyelitis; Prosthesis-Related Infections; Staphylococcal Infections | 2000 |
Predictors of symptom resolution in patients with community-acquired pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Female; Gastrointestinal Diseases; Humans; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Predictive Value of Tests; Treatment Outcome | 2000 |
[Oral levofloxacin versus intravenous ceftriaxone and amoxicillin/clavulanic acid in the treatment of community-acquired pneumonia that requires hospitalization].
Topics: Administration, Oral; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Analysis of Variance; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Prospective Studies | 2000 |
Single-dose pharmacokinetics of levofloxacin during continuous veno-venous haemofiltration in critically ill patients.
Topics: Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Critical Care; Female; Half-Life; Hemofiltration; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin | 2001 |
Lack of interaction between levofloxacin and oxycodone: pharmacokinetics and drug disposition.
Topics: Adult; Anti-Infective Agents; Antitussive Agents; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Interactions; Female; Humans; Levofloxacin; Male; Ofloxacin; Oxycodone; Quinolines | 2001 |
Steady-state plasma and intrapulmonary concentrations of levofloxacin and ciprofloxacin in healthy adult subjects.
Topics: Adult; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Levofloxacin; Lung; Male; Middle Aged; Ofloxacin; Reference Values | 2001 |
Effectiveness of levofloxacin for adult community-acquired pneumonia caused by macrolide-resistant Streptococcus pneumoniae: integrated results from four open-label, multicenter, phase III clinical trials.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Erythromycin; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal | 2001 |
Safety and pharmacokinetics of multiple 750-milligram doses of intravenous levofloxacin in healthy volunteers.
Topics: Adult; Anti-Infective Agents; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin | 2001 |
Pharmacokinetic evaluation of oral levofloxacin in human immunodeficiency virus-infected subjects receiving concomitant antiretroviral therapy.
Topics: Administration, Oral; Alkynes; Anti-HIV Agents; Anti-Infective Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Interactions; HIV Infections; Humans; Levofloxacin; Nelfinavir; Ofloxacin; Oxazines; Prospective Studies | 2001 |
Patient-initiated treatment of uncomplicated recurrent urinary tract infections in young women.
Topics: Adult; Algorithms; Anti-Infective Agents, Urinary; Feasibility Studies; Female; Follow-Up Studies; Humans; Levofloxacin; Middle Aged; Ofloxacin; Patient Compliance; Patient Satisfaction; Prospective Studies; Reagent Kits, Diagnostic; Recurrence; Self Administration; Self Care; Urinary Tract Infections | 2001 |
A controlled trial of a critical pathway for treating community-acquired pneumonia: the CAPITAL study. Community-Acquired Pneumonia Intervention Trial Assessing Levofloxacin.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Canada; Community-Acquired Infections; Critical Pathways; Hospitalization; Humans; Injections, Intravenous; Length of Stay; Levofloxacin; Ofloxacin; Pneumonia; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2001 |
Once-daily oral gatifloxacin versus oral levofloxacin in treatment of uncomplicated skin and soft tissue infections: double-blind, multicenter, randomized study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcus aureus; Treatment Outcome | 2001 |
Randomized, double-blind, comparative study of levofloxacin and ofloxacin in the treatment of complicated urinary tract infections.
Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Urinary Tract Infections | 1999 |
Tissue and serum concentrations of levofloxacin in orthopaedic patients.
Topics: Adult; Aged; Anti-Infective Agents; Bone and Bones; Female; Humans; Intraoperative Care; Levofloxacin; Male; Middle Aged; Muscles; Ofloxacin; Orthopedics; Tissue Distribution | 2001 |
Randomized, double-blind study comparing 5- and 7-day regimens of oral levofloxacin in patients with acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis, Chronic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome | 2001 |
Human aqueous humor levels of oral ciprofloxacin, levofloxacin, and moxifloxacin.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Aza Compounds; Biological Availability; Cataract Extraction; Ciprofloxacin; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Ofloxacin; Prospective Studies; Quinolines; Tissue Distribution | 2001 |
[Antituberculosis effect of levofloxacin].
Topics: Adolescent; Adult; Aged; Animals; Antitubercular Agents; Humans; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Tuberculosis | 2000 |
Levofloxacin penetration into epithelial lining fluid as determined by population pharmacokinetic modeling and monte carlo simulation.
Topics: Adolescent; Adult; Anti-Infective Agents; Computer Simulation; Epithelial Cells; Humans; Levofloxacin; Models, Biological; Monte Carlo Method; Ofloxacin | 2002 |
Pharmacokinetics of levofloxacin during continuous venovenous hemodiafiltration and continuous venovenous hemofiltration in critically ill patients.
Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Critical Illness; Female; Half-Life; Hemodiafiltration; Hemofiltration; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin | 2002 |
Absence of a pharmacokinetic interaction between digoxin and levofloxacin.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Kinetics; Levofloxacin; Male; Middle Aged; Ofloxacin; Placebos | 2002 |
Vitreous penetration of levofloxacin in the uninflamed phakic human eye.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retinal Perforations; Tablets; Vitrectomy; Vitreous Body | 2002 |
Pharmacokinetics of multiple intravenous instillation of levofloxacin in Chinese healthy subjects.
Topics: Adult; Anti-Infective Agents; Asian People; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin | 2002 |
Penetration of levofloxacin into skin tissue after oral administration of multiple 750 mg once-daily doses.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Skin; Skin Diseases; Tissue Distribution | 2002 |
A controlled, double-blind, multicenter study comparing clarithromycin extended-release tablets and levofloxacin tablets in the treatment of community-acquired pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Treatment Outcome | 2002 |
Levofloxacin is effective for inflammatory acne and achieves high levels in the lesions: an open study.
Topics: Acne Vulgaris; Adolescent; Adult; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Propionibacterium acnes; Treatment Outcome | 2002 |
Once-daily, high-dose levofloxacin versus ticarcillin-clavulanate alone or followed by amoxicillin-clavulanate for complicated skin and skin-structure infections: a randomized, open-label trial.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clavulanic Acids; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Skin Diseases; Ticarcillin; Treatment Outcome | 2002 |
Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk.
Topics: Administration, Oral; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Biopsy, Needle; Humans; Levofloxacin; Male; Ofloxacin; Prospective Studies; Prostate; Prostatic Neoplasms; Risk Factors; Ultrasonography, Interventional; Urinary Tract Infections | 2002 |
A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Azithromycin; Ceftriaxone; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Severity of Illness Index | 2002 |
Open-label, randomized comparison of the efficacy and tolerability of clarithromycin, levofloxacin, and cefuroxime axetil in the treatment of adults with acute bacterial exacerbations of chronic bronchitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Bronchitis, Chronic; Cefuroxime; Clarithromycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome | 2002 |
Pharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unit.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Area Under Curve; Creatinine; Critical Illness; Female; Half-Life; Humans; Injections, Intravenous; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Time Factors | 2002 |
Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bronchiolitis; Bronchitis; Drug Therapy, Combination; Erythromycin; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Sinusitis; Syndrome; Treatment Outcome | 2002 |
[Community-acquired pneumonia: usefulness of clinical presentation in the selection of antibiotic treatment].
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Community-Acquired Infections; Female; Hospitalization; Humans; Length of Stay; Levofloxacin; Male; Middle Aged; Ofloxacin; Penicillins; Pneumonia, Bacterial; Treatment Outcome | 2002 |
Levofloxacin based regimens for the eradication of Helicobacter pylori.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Patient Compliance; Prospective Studies; Treatment Outcome | 2002 |
[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactams; Drug Administration Schedule; Female; Humans; Lactams; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatic Hyperplasia; Urinary Bladder, Neurogenic; Urinary Tract Infections | 2002 |
[Ceftriaxone versus Levofloxacin for antibiotic therapy in patients with acute cholangitis].
Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bacteriological Techniques; Bile; Ceftriaxone; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Data Interpretation, Statistical; Drug Resistance, Bacterial; Humans; Infusions, Intravenous; Levofloxacin; Metronidazole; Middle Aged; Ofloxacin; Prospective Studies; Time Factors | 2003 |
Tissue and serum concentrations of levofloxacin 500 mg administered intravenously or orally for antibiotic prophylaxis in biliary surgery.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Bile; Biliary Tract Surgical Procedures; Cholecystectomy; Chromatography, High Pressure Liquid; Female; Gallbladder; Half-Life; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Spectrometry, Fluorescence | 2003 |
[Comparison of the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Sinusitis | 2000 |
[Clinical investigation of 0.3% levofloxacin eyedrops on the treatment of cases with acute bacterial conjunctivitis and bacterial keratitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Conjunctivitis, Bacterial; Eye Infections, Bacterial; Female; Humans; Keratitis; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions | 2000 |
[Levofloxacin versus beta-lactamic therapy in community acquired pneumonia that requires hospitalization].
Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Clavulanic Acid; Community-Acquired Infections; Drug Therapy, Combination; Female; Hospitalization; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 2002 |
Clostridium difficile-associated diarrhoea in patients with community-acquired lower respiratory infection being treated with levofloxacin compared with beta-lactam-based therapy.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Chi-Square Distribution; Clostridioides difficile; Community-Acquired Infections; Diarrhea; Female; Humans; Levofloxacin; Male; Ofloxacin; Prospective Studies; Respiratory Tract Infections | 2003 |
Levofloxacin for prophylaxis in breast cancer surgery compared with ofloxacin.
Topics: Aged; Antibiotic Prophylaxis; Breast Neoplasms; Female; Humans; Levofloxacin; Mastectomy; Middle Aged; Ofloxacin; Regression Analysis; Staphylococcus aureus; Surgical Wound Infection | 2002 |
Randomized controlled study of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy as second-line treatment for Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Benzimidazoles; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Rabeprazole; Rifabutin; Treatment Outcome | 2003 |
A phase III clinical trial of 0.5% levofloxacin ophthalmic solution versus 0.3% ofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Child; Child, Preschool; Conjunctiva; Conjunctivitis, Bacterial; Double-Blind Method; Female; Humans; Infant; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Prospective Studies; Safety; Treatment Outcome | 2003 |
Efficacy and safety of azithromycin vs levofloxacin in the outpatient treatment of acute bacterial exacerbations of chronic bronchitis.
Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacterial Infections; Bronchitis, Chronic; Double-Blind Method; Female; Humans; Levofloxacin; Logistic Models; Male; Middle Aged; Multivariate Analysis; Ofloxacin | 2003 |
[A prospective, controlled, non-randomized study of three cohorts to test the effectiveness of two antibiotics levofloxacin and cotrimoxazol on antibacterial prophylaxis in neutropenic patients].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Humans; Leukemia; Levofloxacin; Lymphoma; Middle Aged; Neutropenia; Ofloxacin; Opportunistic Infections; Prospective Studies; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2003 |
[Efficacy of the drug tavanik (levofloxacin) in acute and maxillary sinusitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Maxillary Sinusitis; Middle Aged; Ofloxacin | 2003 |
Effects of three fluoroquinolones on QT interval in healthy adults after single doses.
Topics: Adult; Aged; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines | 2003 |
[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections].
Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Enterobacteriaceae Infections; Follow-Up Studies; Humans; Levofloxacin; Ofloxacin; Pseudomonas Infections; Recurrence; Safety; Staphylococcal Infections; Streptococcal Infections; Superinfection; Treatment Outcome; Urinary Tract; Urinary Tract Infections | 2003 |
Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: a multicenter, prospective, randomized, open-label study.
Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Ciprofloxacin; Cross Infection; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Staphylococcal; Prospective Studies; Pseudomonas aeruginosa | 2003 |
Lack of bioequivalence when levofloxacin and calcium-fortified orange juice are coadministered to healthy volunteers.
Topics: Adult; Anti-Infective Agents; Area Under Curve; Beverages; Calcium, Dietary; Citrus sinensis; Cross-Over Studies; Female; Food-Drug Interactions; Half-Life; Humans; Levofloxacin; Male; Ofloxacin; Therapeutic Equivalency | 2003 |
Pharmacokinetics and pharmacodynamics of intravenous levofloxacin in patients with early-onset ventilator-associated pneumonia.
Topics: Aged; Anti-Infective Agents; Chromatography, High Pressure Liquid; Critical Illness; Cross Infection; Female; Humans; Injections, Intravenous; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Time Factors; Ventilators, Mechanical | 2003 |
Perioperative antibiotic prophylaxis in ureteroscopic stone removal.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antibiotic Prophylaxis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Perioperative Care; Probability; Prospective Studies; Reference Values; Risk Assessment; Treatment Outcome; Ureteral Calculi; Ureteroscopy; Urinary Tract Infections | 2003 |
Steady-state plasma and bronchopulmonary concentrations of intravenous levofloxacin and azithromycin in healthy adults.
Topics: Adult; Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Area Under Curve; Azithromycin; Blood Urea Nitrogen; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoscopy; Chromatography, High Pressure Liquid; Epithelium; Female; Humans; Injections, Intravenous; Levofloxacin; Lung; Macrophages, Alveolar; Male; Ofloxacin | 2003 |
A phase III, placebo controlled clinical trial of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Child, Preschool; Conjunctivitis, Bacterial; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2003 |
Characterization of the onset and consequences of pneumonia due to fluoroquinolone-susceptible or -resistant Pseudomonas aeruginosa.
Topics: Aged; Anti-Bacterial Agents; Area Under Curve; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Logistic Models; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome | 2003 |
Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study.
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Treatment Outcome | 2003 |
Treatment with levofloxacin does not resolve asymptomatic leucocytospermia--a randomized controlled study.
Topics: Anti-Infective Agents; Humans; Leukocytosis; Levofloxacin; Male; Ofloxacin; Prospective Studies; Spermatozoa | 2003 |
High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm.
Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumonia; Treatment Outcome | 2003 |
Levofloxacin-based triple therapy vs. quadruple therapy in second-line Helicobacter pylori treatment: a randomized trial.
Topics: Adolescent; Adult; Aged; Antacids; Anti-Infective Agents; Bismuth; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Patient Compliance; Prospective Studies; Treatment Outcome | 2003 |
Lack of bioequivalence of levofloxacin when coadministered with a mineral-fortified breakfast of juice and cereal.
Topics: Adult; Animals; Anti-Infective Agents; Beverages; Calcium, Dietary; Citrus; Cross-Over Studies; Edible Grain; Fasting; Female; Food-Drug Interactions; Food, Fortified; Humans; Levofloxacin; Male; Middle Aged; Milk; Ofloxacin; Therapeutic Equivalency | 2003 |
Randomized study of different 'second-line' therapies for Helicobacter pylori infection after failure of the standard 'Maastricht triple therapy'.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Benzimidazoles; Bismuth; Breath Tests; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Pantoprazole; Prospective Studies; Ranitidine; Sulfoxides; Tinidazole; Treatment Failure; Urea | 2003 |
Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial.
Topics: Adult; Aged; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pelvic Pain; Pilot Projects; Prostatitis; Safety; Treatment Outcome | 2003 |
Azithromycin found to be comparable to levofloxacin for the treatment of US travelers with acute diarrhea acquired in Mexico.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Diarrhea; Double-Blind Method; Female; Humans; Levofloxacin; Male; Mexico; Ofloxacin; Travel | 2003 |
Efficacy and safety of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis in pediatric patients.
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Conjunctivitis, Bacterial; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Infant; Levofloxacin; Multicenter Studies as Topic; Ofloxacin; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
[Controlled clinical study on 49 patients of SARS treated by integrative Chinese and Western medicine].
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Levofloxacin; Male; Methylprednisolone; Middle Aged; Ofloxacin; Phytotherapy; Ribavirin; Severe Acute Respiratory Syndrome | 2003 |
Corneal penetration of levofloxacin into the human aqueous humour: a comparison with ciprofloxacin.
Topics: Administration, Topical; Aged; Anti-Infective Agents; Aqueous Humor; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Ciprofloxacin; Cornea; Double-Blind Method; Female; Humans; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions | 2003 |
[Laboratory and clinical study of levofloxacin against Helicobacter pylori].
Topics: Adolescent; Adult; Aged; Drug Resistance, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin | 2003 |
A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity.
Topics: Adult; Anti-Bacterial Agents; Asian People; China; Dermatitis, Phototoxic; Dose-Response Relationship, Drug; Drug Administration Schedule; Enoxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Japan; Levofloxacin; Light; Male; Middle Aged; Ofloxacin; Scotland; Single-Blind Method; Skin Tests; Statistics, Nonparametric; White People | 2003 |
Full-course oral levofloxacin for treatment of hospitalized patients with community-acquired pneumonia.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Hospitalization; Hospitals, Teaching; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Pneumonia, Bacterial; Probability; Prospective Studies; Risk Assessment; Statistics, Nonparametric; Treatment Outcome | 2004 |
High-dose versus low-dose clarithromycin in 1-week triple therapy, including rabeprazole and levofloxacin, for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Benzimidazoles; Breath Tests; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Omeprazole; Rabeprazole; Treatment Outcome | 2004 |
Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with haematological malignancies.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Digestive System; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Levofloxacin; Male; Middle Aged; Neutropenia; Ofloxacin; Pharynx; Staphylococcus aureus | 2004 |
An in vivo study comparing the ocular absorption of levofloxacin and ciprofloxacin prior to phacoemulsification.
Topics: Absorption; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aqueous Humor; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Therapy, Combination; Female; Gas Chromatography-Mass Spectrometry; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Ophthalmic Solutions; Phacoemulsification; Single-Blind Method | 2004 |
Diffusion of levofloxacin into bone and synovial tissues.
Topics: Aged; Anti-Infective Agents; Arthroplasty, Replacement, Hip; Bacteria; Bone and Bones; Chromatography, High Pressure Liquid; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Synovial Membrane | 2004 |
Once-daily oral levofloxacin monotherapy versus piperacillin/tazobactam three times a day: a randomized controlled multicenter trial in patients with febrile neutropenia.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Bacterial Infections; Disease Susceptibility; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Fever of Unknown Origin; Humans; Immunocompromised Host; Levofloxacin; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Penicillanic Acid; Piperacillin; Prospective Studies; Safety; Tazobactam; Treatment Outcome | 2004 |
Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults.
Topics: Aged; Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Azithromycin; Bronchoalveolar Lavage Fluid; Extravascular Lung Water; Female; Fluoroquinolones; Humans; Levofloxacin; Lung; Macrophages, Alveolar; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Urea | 2004 |
An open label, randomized comparative study of levofloxacin and amoxicillin/clavulanic acid in the treatment of purulent sinusitis in adult Thai patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Maxillary Sinusitis; Middle Aged; Ofloxacin; Suppuration | 2004 |
Concentrations of levofloxacin, ofloxacin, and ciprofloxacin in human corneal stromal tissue and aqueous humor after topical administration.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Aqueous Humor; Ciprofloxacin; Corneal Stroma; Double-Blind Method; Female; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Prospective Studies | 2004 |
Measuring the effects of supratherapeutic doses of levofloxacin on healthy volunteers using four methods of QT correction and periodic and continuous ECG recordings.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Cross-Over Studies; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Levofloxacin; Linear Models; Long QT Syndrome; Male; Middle Aged; Myocardial Contraction; Ofloxacin; Syncope; Tachycardia; Time Factors | 2004 |
Relationship between fluoroquinolone area under the curve: minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Area Under Curve; Cross Infection; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Staphylococcal; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcus aureus; Treatment Outcome | 2004 |
Efficacy of 750-mg, 5-day levofloxacin in the treatment of community-acquired pneumonia caused by atypical pathogens.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydophila pneumoniae; Community-Acquired Infections; Double-Blind Method; Drug Administration Schedule; Female; Humans; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Mycoplasma | 2004 |
[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Clinical Protocols; Drug Therapy, Combination; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2004 |
Feasibility and pharmacokinetic study of infusional dexrazoxane and dose-intensive doxorubicin administered concurrently over 96 h for the treatment of advanced malignancies.
Topics: Adult; Antibiotics, Antineoplastic; Cardiovascular Agents; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Heart Failure; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Razoxane; Sarcoma; Sepsis; Treatment Outcome | 2004 |
Clinical experience with levofloxacin in the treatment of pneumonia in ICU patients.
Topics: Anti-Infective Agents; Confidence Intervals; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hospital Mortality; Humans; Infusions, Intravenous; Intensive Care Units; Levofloxacin; Male; Microbial Sensitivity Tests; Odds Ratio; Ofloxacin; Pneumonia, Bacterial; Prognosis; Risk Assessment; Spain; Treatment Outcome | 2004 |
A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Male; Middle Aged; Naphthyridines; Ofloxacin; Treatment Outcome | 2004 |
Experience with levofloxacin in a critical pathway for the treatment of community-acquired pneumonia.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Azithromycin; Cefuroxime; Community-Acquired Infections; Critical Pathways; Drug Therapy, Combination; Female; Humans; Levofloxacin; Longitudinal Studies; Male; Middle Aged; Ofloxacin; Oxygen Inhalation Therapy; Pneumococcal Infections; Pneumonia; Pneumonia, Bacterial; Treatment Outcome | 2004 |
An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae.
Topics: Adult; Amoxicillin; Analysis of Variance; Azithromycin; Blood Bactericidal Activity; Colony Count, Microbial; Cross-Over Studies; Doxycycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Probability; Sensitivity and Specificity; Serum Bactericidal Test; Single-Blind Method; Statistics, Nonparametric; Streptococcus pneumoniae; Sulbactam | 2004 |
Clinical implications of 750 mg, 5-day levofloxacin for the treatment of community-acquired pneumonia.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Community-Acquired Infections; Drug Administration Schedule; Drug Costs; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Treatment Outcome | 2004 |
Cost-effectiveness of full-course oral levofloxacin in severe community-acquired pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Cost-Benefit Analysis; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 2004 |
A 10-day levofloxacin-based therapy in patients with resistant Helicobacter pylori infection: a controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Organometallic Compounds; Pantoprazole; Prospective Studies; Sulfoxides; Treatment Outcome | 2004 |
Pharmacokinetics and pharmacodynamics of intravenous levofloxacin at 750 milligrams and various doses of metronidazole in healthy adult subjects.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Bacteria, Anaerobic; Bacteroides; Biotransformation; Chromatography, High Pressure Liquid; Creatinine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Escherichia coli; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Peptostreptococcus | 2004 |
Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free interval.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Bacterial Infections; Clarithromycin; Disease Progression; Double-Blind Method; Female; Germany; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Statistics, Nonparametric; Treatment Outcome | 2004 |
Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Azithromycin; Canada; Ceftriaxone; Community-Acquired Infections; Drug Administration Schedule; Female; Germany; Humans; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Severity of Illness Index; Treatment Outcome; United States | 2004 |
Levofloxacin versus ceftriaxone plus clarithromycin in the treatment of adults with community-acquired pneumonia requiring hospitalization.
Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Clarithromycin; Cohort Studies; Community-Acquired Infections; Drug Therapy, Combination; Female; Hospitalization; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 2005 |
Pharmacokinetics and intrapulmonary diffusion of levofloxacin in critically ill patients with severe community-acquired pneumonia.
Topics: Aged; Anti-Bacterial Agents; Capillary Permeability; Community-Acquired Infections; Creatinine; Critical Care; Diffusion; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Hospital Mortality; Humans; Infusions, Intravenous; Levofloxacin; Lung; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Pneumonia, Bacterial | 2005 |
Levofloxacin pharmacokinetics in children.
Topics: Administration, Oral; Adolescent; Age Factors; Anti-Infective Agents; Area Under Curve; Biological Availability; Body Weight; Child; Child, Preschool; Drug Administration Schedule; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Inpatients; Levofloxacin; Metabolic Clearance Rate; Ofloxacin | 2005 |
Outpatient care compared with hospitalization for community-acquired pneumonia: a randomized trial in low-risk patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Community-Acquired Infections; Female; Follow-Up Studies; Hospitalization; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Outcome Assessment, Health Care; Patient Satisfaction; Pneumonia, Bacterial; Quality of Life; Risk Factors | 2005 |
[Efficacy of levofloxacin (Tavanic) in the treatment of children with chronic pulmonary diseases].
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Bronchopneumonia; Child; Chronic Disease; Humans; Injections, Intravenous; Levofloxacin; Ofloxacin | 2004 |
Levofloxacin in the treatment of pneumonia in intensive care unit patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Critical Illness; Cross Infection; Drug Administration Schedule; Female; Humans; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Treatment Outcome | 2004 |
Levofloxacin for treatment of ventilator-associated pneumonia: a subgroup analysis from a randomized trial.
Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Cross Infection; Double-Blind Method; Drug Combinations; Drug Resistance, Bacterial; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Thienamycins; Treatment Outcome; Ventilators, Mechanical | 2005 |
Clinical outcomes for hospitalized patients with Legionella pneumonia in the antigenuria era: the influence of levofloxacin therapy.
Topics: Adult; Aged; Anti-Bacterial Agents; Antigens, Bacterial; Female; Humans; Legionnaires' Disease; Levofloxacin; Macrolides; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Time Factors | 2005 |
Antimicrobial chemotherapy for Legionnaires disease: levofloxacin versus macrolides.
Topics: Anti-Bacterial Agents; Case-Control Studies; Disease Outbreaks; Drug Therapy, Combination; Female; Humans; Legionnaires' Disease; Levofloxacin; Macrolides; Male; Middle Aged; Ofloxacin; Rifampin | 2005 |
Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate.
Topics: Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Bacteriuria; Drug Therapy, Combination; Humans; Levofloxacin; Male; Ofloxacin; Prospective Studies; Prostatectomy; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections | 2005 |
Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies.
Topics: Amyloidosis; Anemia, Aplastic; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Humans; Leukemia; Levofloxacin; Lymphoma; Middle Aged; Multiple Myeloma; Neutropenia; Ofloxacin | 2005 |
Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances.
Topics: Acecainide; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Ciprofloxacin; Cross-Over Studies; Drug Interactions; Female; Humans; Kidney; Levofloxacin; Male; Ofloxacin; Procainamide | 2005 |
Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study.
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Cefdinir; Cephalosporins; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Severity of Illness Index; Sinusitis; Treatment Outcome | 2004 |
Levofloxacin disposition over time in aqueous humor of patients undergoing cataract surgery.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Endophthalmitis; Eye; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Time Factors | 2005 |
Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchitis, Chronic; Chronic Disease; Cost-Benefit Analysis; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Haemophilus influenzae; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Nausea; Ofloxacin; Patient Selection; Streptococcus pneumoniae; Treatment Outcome | 2005 |
Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Double-Blind Method; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate-Specific Antigen; Prostatitis | 2005 |
The Early Systemic Prophylaxis of Infection After Stroke study: a randomized clinical trial.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Body Temperature; Brain; Brain Ischemia; C-Reactive Protein; Double-Blind Method; Female; Humans; Infections; Ischemia; Leukocytes; Levofloxacin; Male; Middle Aged; Odds Ratio; Ofloxacin; Placebos; Risk; Stroke; Time Factors; Treatment Outcome | 2005 |
In vitro activities of levofloxacin and comparable agents against middle ear fluid, nasopharyngeal, and oropharyngeal pathogens obtained from Costa Rican children with recurrent otitis media or failing other antibiotic therapy.
Topics: Anti-Bacterial Agents; Child, Preschool; Costa Rica; Haemophilus influenzae; Humans; Infant; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Nasopharynx; Ofloxacin; Oropharynx; Otitis Media with Effusion; Recurrence; Streptococcus pneumoniae; Streptococcus pyogenes; Treatment Failure | 2005 |
One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Azithromycin; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Patient Compliance; Treatment Outcome | 2005 |
Comparison of levofloxacin and cefotaxime combined with ofloxacin for ICU patients with community-acquired pneumonia who do not require vasopressors.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefotaxime; Chi-Square Distribution; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 2005 |
[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications].
Topics: Acute Disease; Adolescent; Adult; Africa, Southern; Aged; Bacterial Infections; Female; France; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Middle Aged; Moraxella catarrhalis; Moraxellaceae Infections; Ofloxacin; Pneumococcal Infections; Prospective Studies; Risk; Sinusitis; Staphylococcal Infections; Treatment Outcome; Tunisia | 2005 |
Levofloxacin- versus metronidazole-based rescue therapy for H. pylori infection in Japan.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Prospective Studies | 2005 |
Pharmacokinetics of levofloxacin after single intravenous and repeat oral administration to cats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Cats; Drug Administration Schedule; Female; Injections, Intravenous; Klebsiella pneumoniae; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin | 2005 |
Comparative bioavailability of two formulations of levofloxacin and effect of sex on bioequivalence analysis. Data from a randomised, 2 x 2 crossover trial in healthy volunteers.
Topics: Adult; Anti-Infective Agents; Area Under Curve; Biological Availability; Body Weight; Chemistry, Pharmaceutical; Cross-Over Studies; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Reproducibility of Results; Sex Characteristics; Therapeutic Equivalency | 2005 |
Efficacy and safety of a novel, single-dose azithromycin microsphere formulation versus 10 days of levofloxacin for the treatment of acute bacterial sinusitis in adults.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Azithromycin; Bacterial Infections; Chemistry, Pharmaceutical; Confidence Intervals; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; International Cooperation; Levofloxacin; Male; Maxillary Sinusitis; Microspheres; Middle Aged; Ofloxacin; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Corneal penetration of fluoroquinolones: aqueous humor concentrations after topical application of levofloxacin 0.5% and ofloxacin 0.3% eyedrops.
Topics: Administration, Topical; Aged; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Chromatography, High Pressure Liquid; Cornea; Female; Humans; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Phacoemulsification | 2005 |
Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacteremia; Bacterial Infections; Double-Blind Method; Female; Fever of Unknown Origin; Humans; Levofloxacin; Logistic Models; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Risk | 2005 |
Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial Infections; Double-Blind Method; Female; Fever; Hospitalization; Humans; Leukocyte Count; Levofloxacin; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Risk; Systemic Inflammatory Response Syndrome | 2005 |
Novel, single-dose microsphere formulation of azithromycin versus 7-day levofloxacin therapy for treatment of mild to moderate community-acquired Pneumonia in adults.
Topics: Adult; Aged; Anti-Bacterial Agents; Azithromycin; Chemistry, Pharmaceutical; Community-Acquired Infections; Double-Blind Method; Female; Humans; Incidence; Levofloxacin; Male; Microspheres; Middle Aged; Ofloxacin; Outpatients; Pneumonia; Serologic Tests; Time Factors; Treatment Outcome | 2005 |
A multicenter, randomized, double-blind, retrospective comparison of 5- and 10-day regimens of levofloxacin in a subgroup of patients aged > or =65 years with community-acquired pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Multicenter Studies as Topic; Ofloxacin; Pneumonia; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2005 |
Pharmacodynamics of levofloxacin in patients with acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Area Under Curve; Bronchitis; Disease Progression; Female; Forced Expiratory Volume; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Predictive Value of Tests; Smoking; Sputum | 2005 |
Efficacy of 1-day prophylaxis medication with fluoroquinolone for prostate biopsy.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy; Drug Administration Schedule; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Prostate; Time Factors | 2005 |
A cost-minimization analysis comparing azithromycin-based and levofloxacin-based protocols for the treatment of patients hospitalized with community-acquired pneumonia: results from the CAP-IN trial.
Topics: Aged; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Community-Acquired Infections; Costs and Cost Analysis; Drug Therapy, Combination; Female; Home Care Services; Hospitalization; Humans; Length of Stay; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; United States | 2005 |
A randomized trial comparing the cardiac rhythm safety of moxifloxacin vs levofloxacin in elderly patients hospitalized with community-acquired pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Community-Acquired Infections; Comorbidity; Double-Blind Method; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart Conduction System; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Quinolines | 2005 |
Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Community-Acquired Infections; Double-Blind Method; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Quinolines; Safety | 2006 |
Pharmacokinetics of ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Female; Humans; Hydrogen-Ion Concentration; Levofloxacin; Male; Middle Aged; Ofloxacin | 2006 |
A study of 4- and 7-day triple therapy with rabeprazole, high-dose levofloxacin and tinidazole rescue treatment for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Benzimidazoles; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Pilot Projects; Rabeprazole; Time Factors; Tinidazole; Treatment Outcome | 2006 |
A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis.
Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Sinusitis; Treatment Outcome | 2006 |
Levofloxacin does not decrease mortality in Staphylococcus aureus bacteraemia when added to the standard treatment: a prospective and randomized clinical trial of 381 patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Chi-Square Distribution; Drug Therapy, Combination; Female; Finland; Humans; Levofloxacin; Male; Middle Aged; Odds Ratio; Ofloxacin; Penicillins; Prospective Studies; Rifampin; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Treatment Failure | 2006 |
Lansoprazole, levofloxacin and amoxicillin triple therapy vs. quadruple therapy as second-line treatment of resistant Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Hong Kong; Humans; Lansoprazole; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Organometallic Compounds; Tetracycline; Treatment Outcome | 2006 |
7-day triple therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and high-dose esomeprazole in patients with known antimicrobial sensitivity.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome | 2006 |
Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of levofloxacin in human plasma.
Topics: Administration, Oral; Anti-Bacterial Agents; Chromatography, Liquid; Humans; Levofloxacin; Male; Ofloxacin; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2006 |
[Levofloxacin-azithromycin combined triple therapy for Helicobacter pylori eradication].
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2006 |
Third-line rescue therapy with levofloxacin after two H. pylori treatment failures.
Topics: Amoxicillin; Antacids; Anti-Bacterial Agents; Bismuth; Breath Tests; Clarithromycin; Drug Therapy, Combination; Enzyme Inhibitors; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Prospective Studies; Protein Synthesis Inhibitors; Tetracycline; Treatment Failure | 2006 |
Effects of three fluoroquinolones on QT analysis after standard treatment courses.
Topics: Analysis of Variance; Aza Compounds; Ciprofloxacin; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Levofloxacin; Long QT Syndrome; Male; Moxifloxacin; Ofloxacin; Quinolines; Statistics, Nonparametric; Torsades de Pointes | 2006 |
Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Calcium Carbonate; Cations; Cross-Over Studies; Cystic Fibrosis; Drug Administration Schedule; Drug Interactions; Female; Gastrointestinal Transit; Humans; Levofloxacin; Male; Ofloxacin; Osteoporosis; Therapeutic Equivalency | 2006 |
Moxifloxacin versus levofloxacin against acute exacerbations of chronic bronchitis: the Latin American Cohort.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Argentina; Aza Compounds; Brazil; Bronchitis, Chronic; Colombia; Double-Blind Method; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Mexico; Middle Aged; Moxifloxacin; Ofloxacin; Peru; Prospective Studies; Quinolines; Treatment Outcome | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime; Double-Blind Method; Endophthalmitis; Eye Infections, Bacterial; Humans; Injections; Levofloxacin; Ofloxacin; Postoperative Complications; Prospective Studies | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Double-Blind Method; Endophthalmitis; Eye Infections, Bacterial; Humans; Injections; Levofloxacin; Ofloxacin; Phacoemulsification; Postoperative Complications; Prospective Studies | 2006 |
Single-dose quinolone treatment in acute gastroenteritis.
Topics: Acute Disease; Adult; Analysis of Variance; Anti-Bacterial Agents; Diarrhea; Female; Gastroenteritis; Humans; Israel; Levofloxacin; Male; Middle Aged; Ofloxacin; Surveys and Questionnaires; Treatment Outcome | 2006 |
Rifaximin-based regimens for eradication of Helicobacter pylori: a pilot study.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Clarithromycin; Drug Therapy, Combination; Dyspepsia; Enzyme Inhibitors; Esomeprazole; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Rifamycins; Rifaximin; Treatment Outcome | 2006 |
Penetration of topically applied levofloxacin 0.5% and ofloxacin 0.3% into the vitreous of the non-inflamed human eye.
Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Levofloxacin; Male; Ofloxacin; Prospective Studies; Retinal Perforations; Spectrometry, Mass, Electrospray Ionization; Vitrectomy; Vitreous Body | 2006 |
Levofloxacin 750-mg for 5 days for the treatment of hospitalized Fine Risk Class III/IV community-acquired pneumonia patients.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Community-Acquired Infections; Drug Administration Schedule; Hospitalization; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Retrospective Studies; Severity of Illness Index; Streptococcus pneumoniae; Treatment Outcome | 2006 |
Open study on efficacy and safety of levofloxacin in treatment of uncomplicated typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Typhoid Fever | 2006 |
Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Single-Blind Method; Tuberculosis, Pulmonary | 2006 |
Do intensive care patients need an individualized dosing regimen for levofloxacin?
Topics: Anti-Bacterial Agents; Critical Illness; Female; Humans; Intensive Care Units; Levofloxacin; Male; Middle Aged; Models, Biological; Ofloxacin; Pancreatitis; Pneumonia, Bacterial; Sepsis | 2006 |
Can Helicobacter pylori eradication regimens be shortened in clinical practice? An open-label, randomized, pilot study of 4 and 7-day triple therapy with rabeprazole, high-dose levofloxacin, and tinidazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Benzimidazoles; Breath Tests; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Omeprazole; Pilot Projects; Rabeprazole; Tinidazole; Treatment Outcome | 2006 |
Moxifloxacin versus standard therapy in patients with pneumonia hospitalized after failure of preclinical anti-infective treatment.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; beta-Lactams; Doxycycline; Drug Therapy, Combination; Female; Fluoroquinolones; Hospitalization; Humans; Levofloxacin; Macrolides; Male; Middle Aged; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Quinolines; Treatment Failure | 2006 |
Liver tissue concentrations of levofloxacin after single intravenous administration of 500 mg for antibiotic prophylaxis in liver surgery.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chromatography, High Pressure Liquid; Female; Fluorometry; Hepatectomy; Humans; Levofloxacin; Liver; Male; Middle Aged; Ofloxacin | 2006 |
Short report: antimicrobial susceptibility and genetic characteristics of Haemophilus influenzae isolated from patients with respiratory tract infections between 1987 and 2000, including beta-lactamase-negative ampicillin-resistant strains.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; Ceftriaxone; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Respiratory Tract Infections | 2007 |
Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradication.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Biopsy; Clarithromycin; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Esomeprazole; Female; Follow-Up Studies; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome | 2006 |
Efficacy of the combination of levofloxacin plus ceftazidime in the treatment of hospital-acquired pneumonia in the intensive care unit.
Topics: Aged; Anti-Bacterial Agents; Ceftazidime; Cross Infection; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Intensive Care Units; Italy; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Treatment Outcome | 2006 |
Levofloxacin 750 mg QD for five days versus amoxicillin/clavulanate 875 mg/125 mg BID for ten days for treatment of acute bacterial exacerbation of chronic bronchitis: a post hoc analysis of data from severely ill patients.
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Ofloxacin | 2006 |
Urinary bactericidal activity of extended-release ciprofloxacin (1,000 milligrams) versus levofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Cross-Over Studies; Delayed-Action Preparations; Humans; Levofloxacin; Ofloxacin; Proteus mirabilis; Staphylococcus; Urine | 2006 |
Third-line rescue therapy with levofloxacin is more effective than rifabutin rescue regimen after two Helicobacter pylori treatment failures.
Topics: Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Rifabutin; Treatment Failure | 2006 |
Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500 mg) versus ciprofloxacin (500 mg) in healthy volunteers receiving a single oral dose.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Cross-Over Studies; Female; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Ofloxacin | 2006 |
Clinical study of complicated urinary tract infection using 'The UTI Criteria (Draft Fourth Edition)': measurement methods for pyuria.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cephalosporins; Female; Follow-Up Studies; Humans; Leukocyte Count; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyuria; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Urine | 2006 |
A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteriuria; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Enterococcus faecalis; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Placebos; Pyuria; Single-Blind Method; Treatment Outcome; Urinary Catheterization; Urinary Tract Infections | 2006 |
An open-label, double tympanocentesis study of levofloxacin therapy in children with, or at high risk for, recurrent or persistent acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child, Preschool; Exudates and Transudates; Female; Humans; Infant; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Otitis Media; Paracentesis; Treatment Outcome | 2006 |
Early discharge of hospitalised patients with community-acquired urosepsis when treated with levofloxacin in sequential therapy.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Community-Acquired Infections; Drug Administration Schedule; Female; Hospitalization; Humans; Length of Stay; Levofloxacin; Male; Middle Aged; Ofloxacin; Patient Discharge; Penicillanic Acid; Pilot Projects; Piperacillin; Piperacillin, Tazobactam Drug Combination; Urinary Tract Infections | 2006 |
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Maxillary Sinusitis; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Moraxellaceae Infections; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; Time Factors; Treatment Outcome | 2007 |
A pilot study testing whether concentrations of levofloxacin in interstitial space fluid of soft tissues may serve as a surrogate for predicting its pharmacokinetics in lung.
Topics: Adipose Tissue, White; Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Extracellular Fluid; Female; Humans; Infusions, Intravenous; Levofloxacin; Lung; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Ofloxacin; Pilot Projects; Tissue Distribution | 2007 |
Time of administration of a single dose of oral levofloxacin and its effect in infectious complications from transrectal prostate biopsy.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biopsy, Needle; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Postoperative Complications; Prospective Studies; Prostate; Prostatic Neoplasms | 2007 |
Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen.
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Campylobacter Infections; Campylobacter jejuni; Community-Acquired Infections; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Bacterial; Dysentery; Escherichia coli Infections; Female; Humans; Levofloxacin; Male; Military Personnel; Ofloxacin; Salmonella Infections; Thailand | 2007 |
Open-label, randomized comparison trial of long-term outcomes of levofloxacin versus standard antibiotic therapy in acute exacerbations of chronic obstructive pulmonary disease.
Topics: Amoxicillin; Anti-Infective Agents; Cefuroxime; Clarithromycin; Female; Follow-Up Studies; Forced Expiratory Volume; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Oximetry; Pulmonary Disease, Chronic Obstructive; Quality of Life; Recurrence; Survival Rate; Time Factors; Treatment Outcome | 2007 |
Levofloxacin- vs. ranitidine bismuth citrate-containing therapy after H. pylori treatment failure.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ranitidine; Treatment Failure; Treatment Outcome | 2007 |
Levofloxacin vs. ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with haematological malignancies.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ciprofloxacin; Cross Infection; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Fever; Hematologic Neoplasms; Humans; Levofloxacin; Male; Middle Aged; Neutropenia; Ofloxacin; Penicillin V; Treatment Outcome; Viridans Streptococci | 2007 |
The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Hematologic Neoplasms; Humans; Levofloxacin; Male; Neutropenia; Ofloxacin; Retrospective Studies; Stem Cell Transplantation; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous | 2007 |
Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Methotrexate; Middle Aged; Ofloxacin; Quality of Life; Range of Motion, Articular; Severity of Illness Index; Treatment Outcome | 2007 |
Levofloxacin pharmacokinetics in adult cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Kidney Function Tests; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum | 2007 |
Cross-over assessment of serum bactericidal activity of moxifloxacin and levofloxacin versus penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae in healthy volunteers.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Aza Compounds; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Penicillin Resistance; Quinolines; Serum Bactericidal Test; Streptococcus pneumoniae | 2007 |
Effect on carotid atherosclerosis of probucol plus levofloxacin for Chlamydia pneumoniae infection.
Topics: Aged; Anti-Bacterial Agents; Anticholesteremic Agents; Carotid Arteries; Carotid Artery Diseases; Chlamydia Infections; Chlamydophila pneumoniae; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Probucol; Ultrasonography | 2007 |
[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis].
Topics: Adult; Chronic Disease; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Phytotherapy; Prostatitis | 2007 |
Levofloxacin 500 mg once daily versus cefuroxime 250 mg twice daily in patients with acute exacerbations of chronic obstructive bronchitis: clinical efficacy and exacerbation-free interval.
Topics: Aged; Bronchitis, Chronic; Cefuroxime; Female; Heart Failure; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Risk Factors; Treatment Outcome | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; Eye Infections, Bacterial; Female; Humans; Incidence; Lens Implantation, Intraocular; Levofloxacin; Male; Odds Ratio; Ofloxacin; Phacoemulsification; Postoperative Complications; Prospective Studies; Risk Factors | 2007 |
[Clinical research of isatis root eyedrops on the acute bacterial conjunctivitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Conjunctivitis, Bacterial; Double-Blind Method; Drugs, Chinese Herbal; Humans; Isatis; Levofloxacin; Middle Aged; Ofloxacin; Ophthalmic Solutions; Phytotherapy; Plant Roots; Plants, Medicinal; Treatment Outcome | 2007 |
Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial.
Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Dioxolanes; Double-Blind Method; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Piperazines; Prospective Studies; Prostatitis; Quinolones | 2007 |
First-line triple therapy with levofloxacin for Helicobacter pylori eradication.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Ranitidine; Treatment Outcome | 2007 |
Helicobacter pylori eradication with either quadruple regimen with lactoferrin or levofloxacin-based triple therapy: a multicentre study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lactoferrin; Levofloxacin; Male; Middle Aged; Ofloxacin; Rabeprazole; Tinidazole; Treatment Outcome | 2007 |
Levofloxacin-containing triple therapy to eradicate the persistent H. pylori after a failed conventional triple therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Constipation; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Nausea; Ofloxacin; Treatment Outcome; Vomiting | 2007 |
Second-line rescue therapy with levofloxacin after H. pylori treatment failure: a Spanish multicenter study of 300 patients.
Topics: Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Follow-Up Studies; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Treatment Failure; Urea | 2008 |
Clinical trial: levofloxacin-based quadruple therapy was inferior to traditional quadruple therapy in the treatment of resistant Helicobacter pylori infection.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome | 2007 |
A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis.
Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Ciprofloxacin; Double-Blind Method; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis | 2007 |
Levofloxacin-based triple therapy for Helicobacter pylori re-treatment: role of bacterial resistance.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Retreatment | 2007 |
Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia.
Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftriaxone; Child; Child, Preschool; Clarithromycin; Community-Acquired Infections; Drug Therapy, Combination; Erythromycin; Female; Humans; Infant; Infant, Newborn; Levofloxacin; Male; Ofloxacin; Pneumonia; Treatment Outcome | 2007 |
Comparative safety profile of levofloxacin in 2523 children with a focus on four specific musculoskeletal disorders.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Female; Humans; Infant; Levofloxacin; Male; Musculoskeletal Diseases; Ofloxacin; Prospective Studies | 2007 |
The ocular penetration of levofloxacin 1.5% and gatifloxacin 0.3% ophthalmic solutions in subjects undergoing corneal transplant surgery.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Cornea; Corneal Transplantation; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions | 2007 |
Rational selection of patients for antibacterial prophylaxis after chemotherapy.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial Infections; Double-Blind Method; Female; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Neoplasms; Ofloxacin; Patient Selection; Placebos; Risk Factors | 2007 |
Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Cephalosporins; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Urinary Tract Infections | 2007 |
Impact of preemptive warfarin dose reduction on anticoagulation after initiation of trimethoprim-sulfamethoxazole or levofloxacin.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Blood Coagulation; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Female; Humans; International Normalized Ratio; Levofloxacin; Male; Middle Aged; Ofloxacin; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin | 2008 |
Disposition kinetics and dosage regimen of levofloxacin on concomitant administration with paracetamol in crossbred calves.
Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Drug Therapy, Combination; Half-Life; Hybridization, Genetic; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Time Factors | 2007 |
A prospective randomized study to determine the efficacy of preoperative topical levofloxacin in reducing conjunctival bacterial flora.
Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Bacteriological Techniques; Cataract Extraction; Colony Count, Microbial; Conjunctiva; Drug Therapy, Combination; Endophthalmitis; Female; Glaucoma; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Postoperative Complications; Povidone-Iodine; Prospective Studies; Treatment Outcome; Vitrectomy | 2008 |
Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antidiarrheals; Camptothecin; Cholestyramine Resin; Colorectal Neoplasms; Diarrhea; Female; Humans; Irinotecan; Levofloxacin; Male; Middle Aged; Ofloxacin; Time Factors | 2007 |
Identification and pretherapy susceptibility of pathogens in patients with complicated urinary tract infection or acute pyelonephritis enrolled in a clinical study in the United States from November 2004 through April 2006.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Double-Blind Method; Drug Resistance, Multiple, Bacterial; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pyelonephritis; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Urinary Tract Infections | 2007 |
Is levofloxacin necessary to prevent postoperative infections of auricular second-intention wounds?
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ear Auricle; Female; Humans; Levofloxacin; Male; Middle Aged; Mohs Surgery; Ofloxacin; Prospective Studies; Surgical Wound Infection; Wounds and Injuries | 2008 |
Population pharmacokinetics of levofloxacin, gatifloxacin, and moxifloxacin in adults with pulmonary tuberculosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Brazil; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis, Pulmonary | 2008 |
Ocular penetration of levofloxacin, ofloxacin and ciprofloxacin in eyes with functioning filtering blebs: investigator masked, randomised clinical trial.
Topics: Administration, Oral; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Ciprofloxacin; Drug Therapy, Combination; Eye Infections, Bacterial; Filtering Surgery; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Prospective Studies; Single-Blind Method; Surgical Wound Infection | 2008 |
Pharmacokinetics of antofloxacin hydrochloride, a new fluoroquinolone antibiotic, after single oral dose administration in Chinese healthy male volunteers.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Asian People; China; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Humans; Levofloxacin; Male; Ofloxacin; Tissue Distribution | 2008 |
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis; Treatment Outcome; Urinary Catheterization; Urinary Tract Infections | 2008 |
[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis].
Topics: Adult; Anti-Infective Agents, Urinary; Capsules; Chronic Disease; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Levofloxacin; Male; Medicine, Chinese Traditional; Middle Aged; Ofloxacin; Prostatitis; Treatment Outcome | 2008 |
Population pharmacokinetics of levofloxacin as prophylaxis for febrile neutropenia.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Dose-Response Relationship, Drug; Female; Fever; Humans; Japan; Leukemia; Levofloxacin; Lymphoma; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Ofloxacin; Pilot Projects | 2008 |
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis.
Topics: Adult; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Female; Humans; Levofloxacin; Male; Maxillary Sinus; Maxillary Sinusitis; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Ofloxacin; Peroxidase; Pilot Projects; Plasma; Radiography; Time Factors; United States | 2008 |
A cost-minimisation analysis comparing moxifloxacin with levofloxacin plus ceftriaxone for the treatment of patients with community-acquired pneumonia in Germany: results from the MOTIV trial.
Topics: Administration, Oral; Aza Compounds; Ceftriaxone; Community-Acquired Infections; Cost of Illness; Cost-Benefit Analysis; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Follow-Up Studies; Hospitalization; Humans; Infusions, Intravenous; Length of Stay; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Quinolines; Severity of Illness Index; Treatment Outcome | 2008 |
Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination.
Topics: Adrenergic alpha-Antagonists; Adult; Anti-Bacterial Agents; Doxazosin; Drug Therapy, Combination; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Prostatitis | 2008 |
Limited efficacy of a nonrestricted intervention on antimicrobial prescription of commonly used antibiotics in the hospital setting: results of a randomized controlled trial.
Topics: Aged; Anti-Bacterial Agents; Carbapenems; Counseling; Drug Prescriptions; Drug Utilization; Female; Guideline Adherence; Hospitals; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Organizational Policy; Vancomycin | 2008 |
Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study--a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Bacteria; Ceftriaxone; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Quinolines; Severity of Illness Index; Treatment Outcome | 2008 |
Systemic expression of cytokine production in patients with severe pneumococcal pneumonia: effects of treatment with a beta-lactam versus a fluoroquinolone.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cytokines; Female; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukins; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prospective Studies; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
A randomized comparative study of levofloxacin versus amoxicillin/clavulanate for treatment of infants and young children with recurrent or persistent acute otitis media.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Levofloxacin; Male; Ofloxacin; Otitis Media; Treatment Outcome | 2008 |
Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Cystitis; Fluoroquinolones; Humans; Levofloxacin; Male; Naphthyridines; Ofloxacin; Prospective Studies; Prostate; Prostatitis; Rectum | 2008 |
Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Female; Gram-Negative Bacterial Infections; Haemophilus Infections; Humans; Levofloxacin; Liver Function Tests; Male; Middle Aged; Minocycline; Ofloxacin; Pneumococcal Infections; Pneumonia, Bacterial; Tigecycline; Treatment Outcome | 2008 |
[Efficacy of levofloxacin-based triple therapy as second-line Helicobacter pylori eradication].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Data Interpretation, Statistical; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Organometallic Compounds; Pantoprazole; Time Factors; Treatment Outcome | 2008 |
Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Chronic Disease; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Treatment Outcome | 2008 |
Nebulized bacitracin/colimycin: a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacitracin; Chronic Disease; Colistin; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Nebulizers and Vaporizers; Ofloxacin; Pilot Projects; Rhinitis; Sinusitis; Staphylococcal Infections; Staphylococcus aureus | 2008 |
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Escherichia coli Infections; Feces; Female; Humans; Levofloxacin; Loperamide; Male; Military Personnel; Nausea; Ofloxacin; Salmonella Infections; Time Factors; Travel; Turkey; United States | 2007 |
Increased anterior chamber penetration of topical levofloxacin 0.5% after pulsed dosing in cataract patients.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anterior Chamber; Anti-Bacterial Agents; Cataract Extraction; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osmolar Concentration; Phacoemulsification; Postoperative Care; Preoperative Care; Pulse Therapy, Drug; Time Factors | 2009 |
Second-line levofloxacin-based triple schemes for Helicobacter pylori eradication.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Salvage Therapy; Young Adult | 2009 |
Safety and efficacy of intravenous tigecycline in treatment of community-acquired pneumonia: results from a double-blind randomized phase 3 comparison study with levofloxacin.
Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Female; Haemophilus influenzae; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Moraxella catarrhalis; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Streptococcus pneumoniae; Tigecycline; Treatment Outcome | 2009 |
Tigecycline versus levofloxacin for the treatment of community-acquired pneumonia: European experience.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; International Agencies; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Safety; Tigecycline; Treatment Outcome | 2008 |
A comparison of fluoroquinolone penetration into human conjunctival tissue.
Topics: Adult; Aged; Anti-Infective Agents; Aza Compounds; Conjunctiva; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines | 2008 |
Failure of Helicobacter pylori treatment after regimes containing clarithromycin: new practical therapeutic options.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Doxycycline; Female; Furazolidone; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Organometallic Compounds; Prospective Studies; Rabeprazole; Treatment Failure; Treatment Outcome; Urea | 2008 |
Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Carbapenems; Doripenem; Double-Blind Method; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies; Pyelonephritis; Urinary Tract Infections | 2009 |
Levofloxacin for the treatment of pneumonia caused by Streptococcus pneumoniae including multidrug-resistant strains: pooled analysis.
Topics: Aged; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Bacterial | 2009 |
A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis.
Topics: Administration, Topical; Anti-Bacterial Agents; Blepharitis; Chronic Disease; Colony Count, Microbial; Conjunctiva; Conjunctivitis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome | 2009 |
Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Endoscopy, Gastrointestinal; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Organometallic Compounds; Prospective Studies; Salvage Therapy; Tetracycline; Treatment Outcome; Young Adult | 2009 |
Comparative bioavailability of two oral formulations of levofloxacin in healthy Mexican volunteers.
Topics: Administration, Oral; Analysis of Variance; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Levofloxacin; Male; Mexico; Ofloxacin; Tablets; Therapeutic Equivalency; Young Adult | 2009 |
Levofloxacin versus azithromycin on the oropharyngeal carriage and selection of antibacterial- resistant streptococci in the microflora of healthy adults.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Oropharynx; Streptococcaceae; Streptococcal Infections; Young Adult | 2009 |
[Corticoid combined with an antibiotic for chronic nonbacterial prostatitis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Double-Blind Method; Drug Therapy, Combination; Glucocorticoids; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prednisone; Prostatitis; Treatment Outcome; Young Adult | 2009 |
Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Female; Humans; Levofloxacin; Metronidazole; Ofloxacin; Pelvic Inflammatory Disease; Sexually Transmitted Diseases; Vaginosis, Bacterial | 2009 |
Efficacy of a 7-day course of furazolidone, levofloxacin, and lansoprazole after failed Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Infective Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Furazolidone; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Salvage Therapy; Treatment Outcome | 2009 |
[Levofloxacin (Tavanic) in complex therapy of tuberculosis].
Topics: Adult; Animals; Antitubercular Agents; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Levofloxacin; Lung; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Radiography; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2009 |
Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Carbapenems; Doripenem; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Pyelonephritis; Urinary Tract Infections | 2009 |
Efficacy of triple therapy with a proton pump inhibitor, levofloxacin, and amoxicillin as first-line treatment to eradicate Helicobacter pylori.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Proton Pump Inhibitors; Young Adult | 2009 |
Pharmacokinetics of levofloxacin in male camels (Camelus dromedarius).
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Camelus; Cross-Over Studies; Injections, Intramuscular; Injections, Intravenous; Levofloxacin; Male; Ofloxacin | 2009 |
Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Minocycline; Nausea; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Severity of Illness Index; Tigecycline; Treatment Outcome; Vomiting; Young Adult | 2009 |
Bioavailability of two oral formulations of a single dose of levofloxacin 500 mg: an open-label, randomized, two-period crossover comparison in healthy Mexican volunteers.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Chromatography, Thin Layer; Cross-Over Studies; Densitometry; Female; Humans; Levofloxacin; Male; Mexico; Ofloxacin; Tablets; Therapeutic Equivalency; Time Factors; Young Adult | 2009 |
Population pharmacokinetics of oral levofloxacin 500 mg once-daily dosage in community-acquired lower respiratory tract infections: results of a prospective multicenter study in China.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bronchitis, Chronic; China; Community-Acquired Infections; Creatinine; Drug Administration Schedule; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prospective Studies; Recurrence | 2009 |
Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China.
Topics: Administration, Oral; Adolescent; Aged; Anti-Bacterial Agents; China; Dizziness; Drug Administration Schedule; Female; Haemophilus influenzae; Humans; Levofloxacin; Male; Middle Aged; Nausea; Ofloxacin; Prospective Studies; Respiratory Tract Infections; Sleep Initiation and Maintenance Disorders; Streptococcus pneumoniae; Treatment Outcome; Urinary Tract Infections; Withholding Treatment | 2009 |
Pharmacometrics-based dose selection of levofloxacin as a treatment for postexposure inhalational anthrax in children.
Topics: Adolescent; Aging; Anthrax; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Body Weight; Child; Child, Preschool; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Infant; Inhalation Exposure; Injections, Intravenous; Kidney Function Tests; Levofloxacin; Male; Ofloxacin; Spores, Bacterial; Tablets | 2010 |
Antibacterial prophylaxis with levofloxacin in patients after allogeneic stem cell transplantation and neutrophil reconstitution: results from a double-blinded, placebo-controlled phase III trial and overview of recent clinical practice.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Double-Blind Method; Female; Humans; Leukemia, Myeloid, Acute; Levofloxacin; Male; Middle Aged; Myelodysplastic Syndromes; Neutrophils; Ofloxacin; Placebos; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2010 |
Changes in drug susceptibility and the quinolone-resistance determining region of Staphylococcus epidermidis after administration of fluoroquinolones.
Topics: Aged; Aged, 80 and over; Bacterial Proteins; Cataract Extraction; Conjunctiva; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, MDR; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Ophthalmic Solutions; Polymerase Chain Reaction; Prospective Studies; Staphylococcus epidermidis | 2009 |
Clarithromycin-amoxycillin-containing triple therapy: a valid empirical first-line treatment for Helicobacter pylori eradication in Hong Kong?
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Hong Kong; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2009 |
The modified sequential treatment regimen containing levofloxacin for Helicobacter pylori eradication in Turkey.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Rabeprazole; Treatment Outcome; Turkey; Young Adult | 2009 |
[The clinical efficacy and safety of intravenous levofloxacin in the treatment of 4888 patients with bacterial infections: a multi-center trial].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Young Adult | 2009 |
Permeability and concentration of levofloxacin in epithelial lining fluid in patients with lower respiratory tract infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Bronchoalveolar Lavage Fluid; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies; Respiratory Mucosa; Respiratory Tract Infections | 2010 |
Efficacy of H. pylori eradication with a sequential regimen followed by rescue therapy in clinical practice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Italy; Lansoprazole; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Treatment Outcome | 2010 |
Tear concentration and safety of levofloxacin ophthalmic solution 1.5% compared with ofloxacin ophthalmic solution 0.3% after topical administration in healthy adult volunteers.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Half-Life; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Microscopy, Acoustic; Middle Aged; Ofloxacin; Ophthalmic Solutions; Ophthalmoscopy; Tears; Visual Acuity; Young Adult | 2010 |
[Human aqueous humor levels of levofloxacin 0.5%, gatifloxacin 0.3% and levofloxacin 0.3% ophthalmic solution after topical dosing].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Double-Blind Method; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions | 2009 |
[Study of different methods in reducing conjunctival bacteria before cataract surgery].
Topics: Aged; Antibiotic Prophylaxis; Cataract; Cataract Extraction; Conjunctiva; Humans; Levofloxacin; Middle Aged; Ofloxacin; Tobramycin | 2009 |
Clinical trial: clarithromycin vs. levofloxacin in first-line triple and sequential regimens for Helicobacter pylori eradication.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Treatment Outcome; Young Adult | 2010 |
[Levofloxacin-based triple therapy for first-line Helicobacter pylori eradication treatment: a multi-central, randomized, controlled clinical study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Young Adult | 2010 |
Safety and efficacy of levofloxacin 750 mg for 2 weeks or 3 weeks compared with levofloxacin 500 mg for 4 weeks in treating chronic bacterial prostatitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Treatment Outcome | 2010 |
Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers.
Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Reference Standards; Young Adult | 2010 |
Levofloxacin-based and clarithromycin-based triple therapies as first-line and second-line treatments for Helicobacter pylori infection: a randomised comparative trial with crossover design.
Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Cross-Over Studies; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Treatment Outcome; Young Adult | 2010 |
Doxycycline vs. levofloxacin in the treatment of community-acquired pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Doxycycline; Drug Costs; Female; Follow-Up Studies; Humans; Length of Stay; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 2010 |
Comparison of 7- and 14-day first-line therapies including levofloxacin in patients with Helicobacter pylori positive non-ulcer dyspepsia.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Breath Tests; Drug Therapy, Combination; Dyspepsia; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Middle Aged; Ofloxacin | 2010 |
Short-term comparative study of the effects of preserved and unpreserved topical levofloxacin on the human ocular surface.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Benzalkonium Compounds; Conjunctiva; Cornea; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Levofloxacin; Male; Middle Aged; Mucin 5AC; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Secretory Rate; Tears; Toxicity Tests, Acute | 2010 |
Antibiotic prophylaxis in transcatheter treatment of hepatocellular carcinoma: an open randomized prospective study of oral versus intravenous administration.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Carcinoma, Hepatocellular; Cefazolin; Chemoembolization, Therapeutic; Female; Humans; Inflammation Mediators; Infusions, Intra-Arterial; Infusions, Intravenous; Levofloxacin; Liver Neoplasms; Male; Middle Aged; Ofloxacin; Postoperative Complications; Prospective Studies; Treatment Outcome | 2010 |
Efficacy and safety of Levofloxacin, Clarithromycin and Esomeprazol as first line triple therapy for Helicobacter pylori eradication in Middle East. Prospective, randomized, blind, comparative, multicenter study.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Medication Adherence; Middle Aged; Ofloxacin; Omeprazole; Prospective Studies; Single-Blind Method; Young Adult | 2010 |
Efficacy and safety of nemonoxacin versus levofloxacin for community-acquired pneumonia.
Topics: Adult; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Quinolones; Treatment Outcome | 2010 |
Efficacy and safety of moxifloxacin in uncomplicated pelvic inflammatory disease: the MONALISA study.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Double-Blind Method; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Levofloxacin; Metronidazole; Middle Aged; Moxifloxacin; Ofloxacin; Pelvic Inflammatory Disease; Quinolines; Treatment Outcome; Young Adult | 2010 |
In vitro evaluation of IgE-mediated hypersensitivity reactions to quinolones.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Aza Compounds; Basophil Degranulation Test; Ciprofloxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Immediate; Immunologic Tests; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Radioimmunoassay; Sensitivity and Specificity; Young Adult | 2011 |
Comparison of the once-daily levofloxacin-containing triple therapy with the twice-daily standard triple therapy for first-line Helicobacter pylori eradication: a prospective randomised study.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome | 2010 |
Levofloxacin prophylaxis to prevent bacterial infection in chemotherapy-induced neutropenia in acute leukemia.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial Infections; Female; Humans; Leukemia; Levofloxacin; Male; Neutropenia; Ofloxacin; Single-Blind Method | 2009 |
A phase II study of antofloxacin hydrochloride, a novel fluoroquinolone, for the treatment of acute bacterial infections.
Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchitis, Chronic; Demography; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis | 2010 |
Empirical levofloxacin-containing versus clarithromycin-containing sequential therapy for Helicobacter pylori eradication: a randomised trial.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Clarithromycin; Drug Costs; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome; Young Adult | 2010 |
Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration.
Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Aqueous Humor; Drug Therapy, Combination; Endophthalmitis; Female; Humans; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Oxazolidinones; Time Factors; Tissue Distribution; Vitrectomy; Vitreous Body | 2010 |
[Comparative research of the efficacy of the gatifloxacin and levofloxacin for bacterial conjunctivitis in human eyes].
Topics: Adolescent; Adult; Conjunctivitis, Bacterial; Double-Blind Method; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Young Adult | 2010 |
Efficacy and tolerability of first-line triple therapy with levofloxacin and amoxicillin plus esomeprazole or rabeprazole for the eradication of Helicobacter pylori infection and the effect of CYP2C19 genotype: a 1-week, randomized, open-label study in Ch
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors; Rabeprazole | 2010 |
Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial.
Topics: Adult; Antitubercular Agents; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; HIV Infections; Humans; Levofloxacin; Neurologic Examination; Ofloxacin; Research Design; Rifampin; Sample Size; Time Factors; Treatment Outcome; Tuberculosis, Meningeal; Vietnam | 2011 |
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis; Treatment Outcome; Urinary Tract Infections | 2010 |
Bioequivalence study of levofloxacin tablets in healthy Indian volunteers using HPLC.
Topics: Anti-Bacterial Agents; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Half-Life; Humans; India; Indicators and Reagents; Levofloxacin; Male; Ofloxacin; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Therapeutic Equivalency | 2011 |
Pharmacokinetic study of single and multiple oral dose administration of antofloxacin hydrochloride in healthy male volunteers.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Humans; Levofloxacin; Male; Ofloxacin; Young Adult | 2011 |
Ophthalmic antibiotics and antimicrobial resistance a randomized, controlled study of patients undergoing intravitreal injections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aza Compounds; Azithromycin; Conjunctiva; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Intravitreal Injections; Levofloxacin; Middle Aged; Moxifloxacin; Nasopharynx; Ofloxacin; Prospective Studies; Quinolines; Staphylococcal Infections | 2011 |
Pharmacokinetics and safety of MP-376 (levofloxacin inhalation solution) in cystic fibrosis subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Single-Blind Method; Solutions | 2011 |
Levofloxacin inhalation solution (MP-376) in patients with cystic fibrosis with Pseudomonas aeruginosa.
Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Solutions; Sputum; Treatment Outcome | 2011 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult | 2011 |
Clinical effectiveness of once-daily levofloxacin for inflammatory acne with high concentrations in the lesions.
Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Ofloxacin; Propionibacterium acnes; Staphylococcus epidermidis; Young Adult | 2012 |
Pharmacokinetics of intravenous levofloxacin administered at 750 milligrams in obese adults.
Topics: Adult; Anti-Bacterial Agents; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Obesity; Ofloxacin; Young Adult | 2011 |
[A multi-center, randomized, controlled, double blind and double dummy clinical trial of antofloxacin hydrochloride tablet versus levofloxacin tablet for the treatment of acute bacterial infections].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Young Adult | 2011 |
Empirical modified sequential therapy containing levofloxacin and high-dose esomeprazole in second-line therapy for Helicobacter pylori infection: a multicentre clinical trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Breath Tests; Cytochrome P-450 CYP2C19; DNA Gyrase; Drug Monitoring; Esomeprazole; Female; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome; Urea | 2011 |
Efficacy of levofloxacin and rifaximin based quadruple therapy in Helicobacter pylori associated gastroduodenal disease: a double-blind, randomized controlled trial.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Peptic Ulcer; Prospective Studies; Rifamycins; Rifaximin | 2011 |
Quadruple therapy with medications containing either rufloxacin or furazolidone as a rescue regimen in the treatment of Helicobacter pylori-infected dyspepsia patients: a randomized pilot study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; China; Drug Therapy, Combination; Female; Fluoroquinolones; Furazolidone; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Organometallic Compounds; Pantoprazole; Pilot Projects; Salvage Therapy; Treatment Outcome; Young Adult | 2011 |
Randomized comparison of two nonbismuth-containing rescue therapies for Helicobacter pylori.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Treatment Outcome | 2011 |
Effectiveness of levofloxacin in enteric fever.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Ofloxacin; Treatment Outcome; Typhoid Fever; Young Adult | 2011 |
Second-line levofloxacin-based triple therapy's efficiency for Helicobacter pylori eradication in patients with peptic ulcer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Intention to Treat Analysis; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Peptic Ulcer; Treatment Outcome; Young Adult | 2011 |
A randomized study comparing levofloxacin, omeprazole, nitazoxanide, and doxycycline versus triple therapy for the eradication of Helicobacter pylori.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Doxycycline; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Intention to Treat Analysis; Lansoprazole; Levofloxacin; Male; Middle Aged; Nitro Compounds; Ofloxacin; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Recurrence; Thiazoles; Young Adult | 2011 |
Population pharmacokinetics and penetration into prostatic, seminal, and vaginal fluid for ciprofloxacin, levofloxacin, and their combination.
Topics: Adolescent; Adult; Body Fluids; Ciprofloxacin; Cross-Over Studies; Drug Combinations; Drug Interactions; Female; Humans; Levofloxacin; Male; Ofloxacin; Prostate; Semen; Seminal Vesicles; Tissue Distribution; Vagina; Young Adult | 2011 |
Randomized phase III trial of docetaxel plus carboplatin with or without levofloxacin prophylaxis in elderly patients with advanced non-small cell lung cancer: the APRONTA trial.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Docetaxel; Double-Blind Method; Dyspnea; Female; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Leukopenia; Levofloxacin; Lung Neoplasms; Male; Middle Aged; Neutropenia; Ofloxacin; Pain; Taxoids | 2011 |
[Clinical study of levofloxacin 500 mg qd in the treatment of cervicitis and intrauterine infections caused by Chlamydia trachomatis].
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Drug Administration Schedule; Endometritis; Female; Glycosuria; Guanosine Triphosphate; Humans; Levofloxacin; Ofloxacin; Product Surveillance, Postmarketing; Treatment Outcome; Uterine Cervicitis; Young Adult | 2011 |
[Prevention of peri-operative infection with sequential therapy of levofloxacin in patients undergoing laparoscopic hysterectomy, laparoscopic assisted vaginal hysterectomy and transvaginal hysterectomy].
Topics: Antibiotic Prophylaxis; Female; Humans; Hysterectomy; Intraoperative Period; Levofloxacin; Middle Aged; Ofloxacin; Surgical Wound Infection; Treatment Outcome | 2011 |
Bronchopulmonary pharmacokinetic and pharmacodynamic profiles of levofloxacin 750 mg once daily in adults undergoing treatment for acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve; Bronchitis, Chronic; Bronchoalveolar Lavage Fluid; Bronchoscopy; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Leukocyte Count; Levofloxacin; Macrophages, Alveolar; Male; Middle Aged; Ofloxacin; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Urea; Young Adult | 2012 |
Comparison of levofloxacin-containing sequential and standard triple therapies for the eradication of Helicobacter pylori.
Topics: Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Esomeprazole; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Treatment Outcome; Young Adult | 2012 |
Assessment of Helicobacter pylori eradication rate of triple combination therapy containing levofloxacin.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors | 2011 |
Assessment of pharmacokinetic proportionality of levofloxacin and cyclosporine over a 100-fold dose range in healthy human volunteers.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Cyclosporine; Dose-Response Relationship, Drug; Half-Life; Humans; Immunosuppressive Agents; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Tandem Mass Spectrometry; Young Adult | 2012 |
Efficacy of 5-day levofloxacin-containing concomitant therapy in eradication of Helicobacter pylori infection.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Tinidazole; Treatment Outcome; Young Adult | 2012 |
Randomized comparison of two non-bismuth-containing second-line rescue therapies for Helicobacter pylori.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Taiwan | 2012 |
Comparison of corneal and aqueous humor penetration of moxifloxacin, gatifloxacin and levofloxacin during keratoplasty.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Aza Compounds; Biological Availability; Cornea; Female; Fluoroquinolones; Gatifloxacin; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines | 2012 |
Levofloxacin versus clarithromycin in a 10 day triple therapy regimen for first-line Helicobacter pylori eradication: a single-blind randomized clinical trial.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors; Single-Blind Method; Spain; Time Factors; Treatment Outcome; Urea; Young Adult | 2012 |
Antibiotic prophylaxis in catheter-associated urinary infections.
Topics: Antibiotic Prophylaxis; Female; Humans; Levofloxacin; Male; Ofloxacin; Urinary Catheterization; Urinary Tract Infections | 2012 |
Efficacy and tolerability of a third-line, levofloxacin-based, 10-day sequential therapy in curing resistant Helicobacter pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies; Proton Pump Inhibitors; Tetracycline; Treatment Outcome | 2012 |
Effectiveness of 1.25 % povidone-iodine combined with topical levofloxacin against conjunctival flora in intravitreal injection.
Topics: Angiogenesis Inhibitors; Anti-Infective Agents, Local; Antibodies, Monoclonal, Humanized; Bacteria; Bevacizumab; Conjunctiva; Disinfection; Drug Therapy, Combination; Endophthalmitis; Humans; Intravitreal Injections; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Povidone-Iodine; Prospective Studies; Ranibizumab; Single-Blind Method; Treatment Outcome | 2012 |
Helicobacter pylori infection: sequential therapy followed by levofloxacin-containing triple therapy provides a good cumulative eradication rate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Treatment Outcome; Young Adult | 2012 |
High-dose levofloxacin in community-acquired pneumonia: a randomized, open-label study.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies | 2012 |
Switch therapy in hospitalized patients with community-acquired pneumonia: tigecycline vs. levofloxacin.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Tigecycline; Treatment Outcome | 2012 |
Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients.
Topics: Adult; Anti-Bacterial Agents; Asian People; Ciprofloxacin; Escherichia coli Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Staphylococcal Infections; Staphylococcus epidermidis; Treatment Outcome | 2012 |
Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dioxolanes; Disk Diffusion Antimicrobial Tests; Double-Blind Method; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Piperazines; Respiratory Tract Infections; Treatment Outcome; Urinary Tract Infections; Young Adult | 2012 |
The efficacy of second-line anti-Helicobacter pylori therapy using an extended 14-day levofloxacin/amoxicillin/proton-pump inhibitor treatment--a pilot study.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Drug Therapy, Combination; Female; Helicobacter Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Proton Pump Inhibitors; Taiwan; Time Factors; Treatment Outcome; Urea | 2012 |
Comparison of 10 day bismuth quadruple therapy with high-dose metronidazole or levofloxacin for second-line Helicobacter pylori therapy: a randomized controlled trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Organometallic Compounds; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2013 |
Levofloxacin-containing triple and sequential therapy or standard sequential therapy as the first line treatment for Helicobacter pylori eradication in China.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Breath Tests; China; Drug Therapy, Combination; Female; Helicobacter Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Urea; Young Adult | 2012 |
TNFα antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Double-Blind Method; Etanercept; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Immunoglobulin G; Levofloxacin; Male; Middle Aged; Ofloxacin; Prednisone; Pulmonary Disease, Chronic Obstructive; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
[Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction].
Topics: Adult; Capsules; Chronic Disease; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Phytotherapy; Prazosin; Prostatitis; Treatment Outcome; Young Adult | 2012 |
Pharmacokinetics of levofloxacin in Japanese quails (Coturnix japonica) following intravenous and oral administration.
Topics: Absorption; Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Coturnix; Cross-Over Studies; Escherichia coli; Female; Half-Life; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin | 2012 |
Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Community-Acquired Infections; Double-Blind Method; Female; Humans; Levofloxacin; Macrolides; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Treatment Outcome; Triazoles; Young Adult | 2013 |
Effect of fluoroquinolone resistance on 14-day levofloxacin triple and triple plus bismuth quadruple therapy.
Topics: Adult; Aged; Anti-Bacterial Agents; Bismuth; Breath Tests; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pilot Projects; Prospective Studies; Treatment Outcome; Urea; Young Adult | 2013 |
Efficacy of two levofloxacin-containing second-line therapies for Helicobacter pylori: a pilot study.
Topics: Adult; Aged; Anti-Bacterial Agents; Antigens, Bacterial; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Feces; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Medication Adherence; Middle Aged; Ofloxacin; Pilot Projects; Treatment Outcome; Turkey; Young Adult | 2013 |
Readmissions for warfarin-related bleeding in pediatric patients after hospital discharge.
Topics: Adolescent; Anti-Bacterial Agents; Anticoagulants; Asian; Cardiac Surgical Procedures; Child; Child, Preschool; Citalopram; Female; Hospital Information Systems; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Patient Readmission; Postoperative Hemorrhage; Risk Factors; Selective Serotonin Reuptake Inhibitors; Time Factors; Warfarin | 2013 |
[Infectious exacerbation of chronic obstructive pulmonary disease: prospects for high-dose levofloxacin therapy].
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2013 |
Quinolone prophylaxis for the prevention of BK virus infection in kidney transplantation: study protocol for a randomized controlled trial.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Canada; Clinical Protocols; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Humans; Kidney Failure, Chronic; Kidney Transplantation; Levofloxacin; Ofloxacin; Pilot Projects; Polyomavirus Infections; Research Design; Time Factors; Treatment Outcome; Tumor Virus Infections | 2013 |
Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Azithromycin; CD4-Positive T-Lymphocytes; Chronic Disease; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Rifampin; Sarcoidosis; Severity of Illness Index; Single-Blind Method; Skin Diseases; Transcriptome; Treatment Outcome; Young Adult | 2013 |
Efficacy of levofloxacin versus cefuroxime in treating acute exacerbations of chronic obstructive pulmonary disease.
Topics: Aged; Anti-Bacterial Agents; Bacteria; Cefuroxime; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Patient Acuity; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2013 |
Levofloxacin pharmacokinetics and tissue residue concentrations after oral administration in Bilgorajska geese.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Chickens; Geese; Levofloxacin; Ofloxacin | 2021 |
Efficacy and Safety of Antofloxacin-Based Triple Therapy for Helicobacter pylori Eradication Failure in China.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; China; Drug Therapy, Combination; Esomeprazole; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Proton Pump Inhibitors; Treatment Outcome | 2022 |
1577 other study(ies) available for ofloxacin and levofloxacin
| Article | Year |
|---|---|
Chiral DNA gyrase inhibitors. 2. Asymmetric synthesis and biological activity of the enantiomers of 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H- pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid (ofloxacin).
Topics: Anti-Bacterial Agents; Ofloxacin; Oxazines; Stereoisomerism; Topoisomerase II Inhibitors | 1987 |
Synthesis and bacterial DNA gyrase inhibitory properties of a spirocyclopropylquinolone derivative.
Topics: Animals; Bacteroides; Chemical Phenomena; Chemistry; Ciprofloxacin; Escherichia coli; Mice; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus; Topoisomerase II Inhibitors | 1988 |
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis | 1999 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Culture Media; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Indicators and Reagents; Kinetics; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Omeprazole; Staphylococcus aureus; Structure-Activity Relationship | 2007 |
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones.
Topics: Anti-Infective Agents; DNA; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Mycobacterium leprae; Quinolones; Topoisomerase II Inhibitors | 2007 |
Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Culture Media; DNA Gyrase; Drug Resistance, Bacterial; Enterococcus faecalis; Fluoroquinolones; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Interaction of drug based binuclear mixed-ligand complexes with DNA.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity | 2009 |
Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype.
Topics: Bacterial Proteins; Drug Resistance, Bacterial; Electroporation; Genotype; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Quinolones; Salmonella enterica | 2009 |
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.
Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes | 2010 |
SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Stenotrophomonas maltophilia | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium | 2010 |
Novel variants of the qnrB gene, qnrB22 and qnrB23, in Citrobacter werkmanii and Citrobacter freundii.
Topics: Animals; Bacterial Proteins; Chickens; Citrobacter; Citrobacter freundii; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Quinolones; Swine | 2010 |
A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities.
Topics: Animals; Anti-Infective Agents; Antiviral Agents; Bacteria; Cell Line; Chlorocebus aethiops; Drug Evaluation, Preclinical; Fungi; Herpesvirus 1, Human; Mannich Bases; Microbial Sensitivity Tests; Parainfluenza Virus 3, Human; Pyrones; Spectrum Analysis; Vero Cells | 2010 |
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Studies on the antimicrobial properties of N-acylated ciprofloxacins.
Topics: Acylation; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bartonella; Bartonella Infections; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections | 2012 |
The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel.
Topics: Anti-Bacterial Agents; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Models, Molecular; Potassium Channel Blockers; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Polyketide Synthases; Structure-Activity Relationship; Vero Cells | 2019 |
Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules.
Topics: Antitubercular Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Polyketide Synthases; Quinolones; Structure-Activity Relationship | 2021 |
WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Piperidines; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcus pneumoniae; Structure-Activity Relationship | 2022 |
[Efficacy of levofloxacin on typhoid fever].
Topics: Aged; Female; Humans; Levofloxacin; Ofloxacin; Typhoid Fever | 1992 |
The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI.
Topics: Bacteriuria; Esterases; Evaluation Studies as Topic; Humans; Japan; Leukocyte Count; Levofloxacin; Nitrates; Ofloxacin; Pyuria; Reagent Kits, Diagnostic; Urinary Catheterization; Urinary Tract Infections; Urine | 1992 |
In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Levofloxacin; Mice; Microbial Sensitivity Tests; Ofloxacin; Stereoisomerism | 1992 |
The effect of levofloxacin, an optically-active isomer of ofloxacin, on fecal microflora in human volunteers.
Topics: Adult; Bacteria; Feces; Humans; Levofloxacin; Male; Ofloxacin; Reference Values; Yeasts | 1992 |
[A study on the concentrations of levofloxacin in the gallbladder tissue and bile of patients].
Topics: Adipose Tissue; Administration, Oral; Adult; Aged; Aged, 80 and over; Bile; Cholelithiasis; Female; Gallbladder; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 1992 |
Efficacy of a new quinolone, levofloxacin in patients with surgical infections.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Postoperative Complications; Surgical Wound Infection | 1992 |
[Fundamental study on levofloxacin in the field of obstetrics and gynecology].
Topics: Administration, Oral; Adult; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Ovary; Uterus | 1992 |
[Pharmacokinetic and clinical evaluation of levofloxacin in obstetrics and gynecology].
Topics: Administration, Oral; Adult; Bacterial Infections; Female; Genital Diseases, Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Ovary; Uterus | 1992 |
[Pharmacokinetic and clinical evaluation of levofloxacin in obstetrical and gynecological field].
Topics: Administration, Oral; Adult; Bacterial Infections; Female; Genital Diseases, Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Ovary; Uterus | 1992 |
[Clinical pharmacology and efficacy of levofloxacin in elderly patients].
Topics: Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Kidney Diseases; Levofloxacin; Male; Ofloxacin; Respiratory Tract Infections | 1992 |
[Sputum penetration of levofloxacin and its clinical efficacy in patients with chronic lower respiratory tract infections].
Topics: Aged; Chronic Disease; Drug Evaluation; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections; Sputum | 1992 |
[Laboratory and clinical studies on levofloxacin].
Topics: Adult; Aged; Bacteria; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Respiratory Tract Infections; Sputum | 1992 |
[Chemotherapy of biliary tract infections (XXXVII). Excretion into bile and gallbladder tissue levels of levofloxacin and its clinical effect in biliary tract infections].
Topics: Adult; Aged; Bile; Cholangitis; Cholecystitis; Drug Evaluation; Female; Gallbladder; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 1992 |
[Penetration of levofloxacin in bile].
Topics: Aged; Bile; Cholangitis; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 1992 |
[Levofloxacin in the field of dermatology].
Topics: Adolescent; Adult; Animals; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Rats; Skin; Skin Diseases, Infectious; Staphylococcal Infections; Staphylococcus aureus | 1992 |
[Levofloxacin in obstetrics and gynecology].
Topics: Adult; Drug Evaluation; Endometritis; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pelvic Inflammatory Disease; Uterine Cervicitis | 1992 |
[Acute nongonococcal epididymitis--pharmacological and therapeutic aspects of levofloxacin].
Topics: Acute Disease; Administration, Oral; Adult; Chlamydia trachomatis; Epididymis; Epididymitis; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Sperm Count; Sperm Motility; Spermatozoa | 1992 |
[Bacteriological and clinical studies on levofloxacin in male gonococcal urethritis].
Topics: Administration, Oral; Adolescent; Adult; Chlamydia trachomatis; Drug Resistance, Microbial; Gonorrhea; Humans; Levofloxacin; Male; Middle Aged; Neisseria gonorrhoeae; Ofloxacin; Urethritis | 1992 |
Levofloxacin (DR 3355), a new quniolone antibacterial agent.
Topics: Animals; Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin | 1992 |
Acute oral toxicity of the new quinolone antibacterial agent levofloxacin in mice, rats and monkeys.
Topics: Animals; Anti-Infective Agents; Behavior, Animal; Female; Lethal Dose 50; Levofloxacin; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Ofloxacin; Rats; Rats, Inbred Strains | 1992 |
Twenty-six-week oral toxicity of the new quinolone antibacterial agent levofloxacin in rats and cynomolgus monkeys.
Topics: Animals; Anti-Infective Agents; Blood Cell Count; Body Weight; Eating; Electrocardiography; Female; Levofloxacin; Macaca fascicularis; Male; Ofloxacin; Organ Size; Rats; Rats, Inbred Strains | 1992 |
Reproductive toxicity of the new quinolone antibacterial agent levofloxacin in rats and rabbits.
Topics: Animals; Anti-Infective Agents; Body Weight; Female; Levofloxacin; Male; Ofloxacin; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Rats, Inbred Strains; Reproduction; Sexual Behavior, Animal; Teratogens | 1992 |
Mutagenicity of the new quinolone antibacterial agent levofloxacin.
Topics: Animals; Anti-Infective Agents; Body Weight; Cell Line; Cell Survival; CHO Cells; Chromosome Aberrations; Cricetinae; DNA; Escherichia coli; Female; Levofloxacin; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagens; Ofloxacin; Pregnancy; Rats; Rats, Inbred F344; Salmonella typhimurium; Sister Chromatid Exchange | 1992 |
Antigenicity of the new quinolone antibacterial agent levofloxacin.
Topics: Anaphylaxis; Animals; Anti-Infective Agents; Antigens; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Levofloxacin; Male; Mice; Mice, Inbred BALB C; Ofloxacin; Passive Cutaneous Anaphylaxis; Rabbits; Rats; Rats, Inbred Strains | 1992 |
Effect of the new quinolone antibacterial agent levofloxacin on multiple organ carcinogenesis initiated with wide-spectrum carcinogens in rats.
Topics: Animals; Anti-Infective Agents; Body Weight; Carcinogens; Drinking; Eating; Levofloxacin; Male; Neoplasms, Experimental; Ofloxacin; Rats; Rats, Inbred F344 | 1992 |
Lack of nephrotoxic effects of the new quinolone antibacterial agent levofloxacin in rabbits.
Topics: Animals; Anti-Infective Agents; Blood Urea Nitrogen; Body Weight; Cephaloridine; Creatinine; Kidney Diseases; Levofloxacin; Male; Ofloxacin; Organ Size; Rabbits | 1992 |
Ophthalmotoxicity and ototoxicity of the new quinolone antibacterial agent levofloxacin in Long Evans rats.
Topics: Animals; Anti-Infective Agents; Electroretinography; Eye Diseases; Female; Hearing; Hearing Disorders; Levofloxacin; Male; Ofloxacin; Rats; Rats, Inbred Strains; Retina; Vision, Ocular | 1992 |
Phototoxic potential of the new quinolone antibacterial agent levofloxacin in mice.
Topics: Animals; Anti-Infective Agents; Enoxacin; Female; Levofloxacin; Light; Mice; Mice, Inbred BALB C; Ofloxacin; Photosensitivity Disorders | 1992 |
Interaction of the new quinolone antibacterial agent levofloxacin with fenbufen in mice.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Levofloxacin; Male; Mice; Ofloxacin; Phenylbutyrates; Seizures | 1992 |
General pharmacology of the new quinolone antibacterial agent levofloxacin.
Topics: Animals; Anti-Infective Agents; Autonomic Nervous System; Behavior, Animal; Cardiovascular System; Cats; Central Nervous System; Digestive System; Dogs; Female; Guinea Pigs; In Vitro Techniques; Levofloxacin; Male; Mice; Ofloxacin; Rabbits; Rats; Rats, Inbred Strains; Respiratory System | 1992 |
[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis].
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Epididymitis; Escherichia coli; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Staphylococcus; Urinary Tract Infections | 1992 |
[Treatment of gonococcal urethritis].
Topics: Adult; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Gonorrhea; Humans; Levofloxacin; Male; Middle Aged; Neisseria gonorrhoeae; Ofloxacin; Urethritis | 1991 |
Attenuated inhibition by levofloxacin, l-isomer of ofloxacin, on GABA response in the dissociated rat hippocampal neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chlorides; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Isomerism; Levofloxacin; Neurons; Ofloxacin; Phenylacetates; Rats; Rats, Wistar | 1995 |
Inhibitory and bactericidal activities of levofloxacin, ofloxacin, erythromycin, and rifampin used singly and in combination against Legionella pneumophila.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Drug Synergism; Drug Therapy, Combination; Erythromycin; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; Time Factors | 1995 |
In vitro antimycobacterial activity of a new quinolone, levofloxacin (DR-3355).
Topics: Animals; Anti-Infective Agents; Colony Count, Microbial; Female; In Vitro Techniques; Levofloxacin; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin | 1995 |
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles.
Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors | 1994 |
Chemotherapeutic activity of levofloxacin (HR 355, DR-3355) against systemic and localized infections in laboratory animals.
Topics: Abscess; Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Female; Granuloma; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Pyelonephritis; Rats; Rats, Wistar; Sepsis; Stereoisomerism; Streptococcus pneumoniae | 1995 |
In vitro activity of levofloxacin and FK-037 against aerobic isolates from spontaneous bacterial peritonitis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria, Aerobic; Ceftizoxime; Enterobacteriaceae; Humans; Isomerism; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Peritonitis; Streptococcus | 1995 |
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis | 1995 |
Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Bites, Human; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Wound Infection | 1995 |
Pharmacodynamics of levofloxacin, ofloxacin, and ciprofloxacin, alone and in combination with rifampin, against methicillin-susceptible and -resistant Staphylococcus aureus in an in vitro infection model.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Rifampin; Staphylococcus aureus; Stereoisomerism | 1994 |
Suggested modifications for disk diffusion susceptibility testing criteria for levofloxacin and sparfloxacin following tests with a predictor panel of ciprofloxacin-resistant clinical isolates.
Topics: Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Reproducibility of Results | 1995 |
Susceptibility to levofloxacin predicted from in vitro susceptibility testing results obtained with ciprofloxacin and with ofloxacin.
Topics: Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1995 |
Premarketing population pharmacokinetic study of levofloxacin in normal subjects and patients with infectious diseases.
Topics: Age Factors; Bayes Theorem; Clinical Trials as Topic; Communicable Diseases; Humans; Levofloxacin; Marketing of Health Services; Meta-Analysis as Topic; Ofloxacin | 1995 |
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin).
Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
Activity of 4-quinolones against Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Culture Media; Gram-Negative Bacteria; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 1994 |
[Intraocular penetration of oral levofloxacin in rabbits].
Topics: Administration, Oral; Albinism, Ocular; Animals; Autoradiography; Eye; Levofloxacin; Melanins; Ofloxacin; Rabbits; Tissue Distribution | 1994 |
Levofloxacin, an optical isomer of ofloxacin, has attenuated epileptogenic activity in mice and inhibitory potency in GABA receptor binding.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cisterna Magna; GABA Antagonists; In Vitro Techniques; Injections; Isomerism; Levofloxacin; Mice; Mice, Inbred Strains; Norfloxacin; Ofloxacin; Phenylacetates; Protein Binding; Receptors, GABA; Seizures | 1994 |
Effect of levofloxacin and ciprofloxacin injection on permeability of the tail vein in mice and skin microvasculature in rats.
Topics: Animals; Anti-Infective Agents; Capillary Permeability; Ciprofloxacin; Diphenhydramine; Hydrogen-Ion Concentration; Injections, Intravenous; Levofloxacin; Male; Mast Cells; Mice; Mice, Inbred BALB C; Microcirculation; Ofloxacin; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Skin; Tail; Veins | 1994 |
Effects of temperature on the bactericidal activities of ciprofloxacin and levofloxacin against Escherichia coli and Pseudomonas aeruginosa.
Topics: Ciprofloxacin; Culture Media; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Stereoisomerism; Temperature | 1994 |
Assessment of the bactericidal activity of sparfloxacin, ofloxacin, levofloxacin, and other fluoroquinolones compared with selected agents of proven efficacy against Listeria monocytogenes.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Listeria monocytogenes; Listeriosis; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
Interpretive criteria and quality control for antimicrobial susceptibility tests of levofloxacin.
Topics: Bacteriological Techniques; Culture Media; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quality Control; Staphylococcus aureus | 1994 |
Involvement of inhibitory and excitatory neurotransmitters in levofloxacin- and ciprofloxacin-induced convulsions in mice.
Topics: Acetamides; Alcohol Oxidoreductases; Animals; Ciprofloxacin; Excitatory Amino Acid Antagonists; Injections, Intravenous; Injections, Spinal; Levofloxacin; Male; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Ofloxacin; Receptors, GABA; Seizures | 1993 |
Minimum inhibitory concentration quality-control guidelines for biapenem, DU-6859a, FK-037, levofloxacin, grepafloxacin, and ceftizoxime when using various National Committee for Clinical Laboratory Standards susceptibility test methods. Quality Control S
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ceftizoxime; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quality Control; Quinolones; Reference Values; Spiro Compounds; Thienamycins | 1994 |
Effects of temperature on the bactericidal activities of ciprofloxacin and levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Body Temperature; Ciprofloxacin; Levofloxacin; Ofloxacin; Staphylococcus aureus; Staphylococcus epidermidis; Temperature | 1994 |
Activity of levofloxacin in a murine model of tuberculosis.
Topics: Animals; Antitubercular Agents; Culture Media; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Stereoisomerism; Tuberculosis, Pulmonary | 1994 |
Postantibiotic effect of DU-6859a and levofloxacin as compared with ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Enterococcus faecalis; Escherichia coli; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1994 |
In vitro and in vivo activities of sparfloxacin against Mycoplasma pneumoniae.
Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Levofloxacin; Lung; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1994 |
Susceptibilities of bacterial isolates from patients with cancer to levofloxacin and other quinolones.
Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Neoplasms; Ofloxacin; Stereoisomerism | 1994 |
[In vitro antituberculous activity of levofloxacin].
Topics: Antitubercular Agents; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin | 1994 |
Inhibitory and bactericidal activities of levofloxacin against Mycobacterium tuberculosis in vitro and in human macrophages.
Topics: Colony Count, Microbial; Humans; In Vitro Techniques; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin | 1994 |
Levofloxacin in vitro activity: results from an international comparative study with ofloxacin and ciprofloxacin.
Topics: Asia; Ciprofloxacin; Europe; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; South America | 1994 |
Mechanistic study of inhibition of levofloxacin absorption by aluminum hydroxide.
Topics: Aluminum Hydroxide; Animals; Buffers; Chemical Phenomena; Chemistry, Physical; Chloroform; Drug Interactions; Enoxacin; Intestinal Absorption; Levofloxacin; Male; Norfloxacin; Ofloxacin; Phosphates; Rats; Rats, Sprague-Dawley | 1993 |
Photodegradation products of levofloxacin in aqueous solution.
Topics: Chromatography, High Pressure Liquid; Indicators and Reagents; Levofloxacin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Ofloxacin; Photochemistry; Spectrophotometry, Ultraviolet | 1993 |
Levofloxacin disk potency and tentative interpretive criteria for susceptibility tests.
Topics: Evaluation Studies as Topic; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1993 |
Induction of resistance of Streptococcus pneumoniae to quinolones in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1993 |
Tentative criteria for confirming the in vitro susceptibilities of Haemophilus influenzae and Neisseria gonorrhoeae to two fluoroquinolones (sparfloxacin and levofloxacin), including quality control parameters.
Topics: Anti-Infective Agents; Fluoroquinolones; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quality Control; Quinolones | 1993 |
Synergy of levofloxacin (L-ofloxacin) and oxacillin against quinolone-resistant Staphylococcus aureus, measured by the time-kill method.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Drug Synergism; Kinetics; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Oxacillin; Staphylococcus aureus | 1993 |
Effect of levofloxacin on glycosaminoglycan and DNA synthesis of cultured rabbit chondrocytes at concentrations inducing cartilage lesions in vivo.
Topics: Animals; Anti-Infective Agents; Cartilage, Articular; Cell Survival; Cells, Cultured; DNA; Glycosaminoglycans; Levofloxacin; Male; Ofloxacin; Rabbits; Sulfates; Sulfur Radioisotopes; Thymidine | 1995 |
In vitro activity of levofloxacin, singly and in combination with rifamycin analogs, against Mycobacterium leprae.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Anti-Infective Agents; Culture Media; Drug Synergism; Drug Therapy, Combination; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium leprae; Ofloxacin; Rifamycins; Thymidine | 1995 |
In vitro antibacterial activity of levofloxacin.
Topics: Anti-Infective Agents; Bacteria; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1995 |
Levofloxacin in patients with severe respiratory tract infection.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Asthma; Bronchitis; Chronic Disease; Clarithromycin; Drug Therapy, Combination; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pseudomonas aeruginosa; Respiratory Tract Infections | 1995 |
Comparison of the in vitro activity of levofloxacin and other antimicrobial agents against vancomycin-susceptible and vancomycin-resistant Enterococcus species.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Vancomycin | 1995 |
In-vitro activity of levofloxacin against clinical isolates of Legionella spp, its pharmacokinetics in guinea pigs, and use in experimental Legionella pneumophila pneumonia.
Topics: Animals; Anti-Infective Agents; Guinea Pigs; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin | 1996 |
[In vitro antimicrobial activity of a new quinolone, levofloxacin, against atypical mycobacteria].
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Nontuberculous Mycobacteria; Ofloxacin | 1995 |
In-vitro susceptibility of Streptococcus pneumoniae to the d- and l-isomers of ofloxacin: interpretive criteria and quality control limits.
Topics: Anti-Infective Agents; Data Interpretation, Statistical; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quality Control; Reproducibility of Results; Stereoisomerism; Streptococcus pneumoniae | 1996 |
A comparison of active site binding of 4-quinolones and novel flavone gyrase inhibitors to DNA gyrase.
Topics: Anti-Infective Agents; Binding Sites; DNA Topoisomerases, Type II; DNA, Superhelical; Escherichia coli; Flavonoids; Levofloxacin; Molecular Structure; Ofloxacin; Plasmids; Structure-Activity Relationship; Substrate Specificity; Topoisomerase II Inhibitors | 1995 |
Susceptibility testing interpretive criteria for levofloxacin when testing respiratory pathogens, Haemophilus influenzae and Moraxella catarrhalis.
Topics: Culture Media; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin | 1996 |
Effect of bile duct ligation and unilateral nephrectomy on brain concentration and convulsant potential of the quinolone antibacterial agent levofloxacin in rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bile Ducts; Brain; Dose-Response Relationship, Drug; Drug Synergism; Infusions, Intravenous; Injections, Intravenous; Levofloxacin; Ligation; Male; Nephrectomy; Ofloxacin; Phenylacetates; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
Transport of levofloxacin in a kidney epithelial cell line, LLC-PK1: interaction with organic cation transporters in apical and basolateral membranes.
Topics: Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Epithelium; Hydrogen-Ion Concentration; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Radioligand Assay; Swine | 1996 |
Effect of levofloxacin-albumin Dacron graft on graft infection.
Topics: Animals; Bacterial Infections; Levofloxacin; Male; Ofloxacin; Polyethylene Terephthalates; Rats; Rats, Sprague-Dawley; Tissue Transplantation | 1995 |
In vitro activities of levofloxacin used alone and in combination with first- and second-line antituberculous drugs against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Interactions; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium bovis; Mycobacterium tuberculosis; Ofloxacin; Stereoisomerism | 1996 |
Prevalence of resistance to three fluoroquinolones: assessment of levofloxacin disk test error rates and surrogate predictors of levofloxacin susceptibility. AST Surveillance Group.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Prevalence; Quality Control | 1996 |
[Effects of intravitreal levofloxacin on the rabbit retina].
Topics: Animals; Anti-Infective Agents; Electroretinography; Evoked Potentials, Visual; Injections; Levofloxacin; Ofloxacin; Rabbits; Retina; Vitreous Body | 1996 |
A new drug delivery system utilizing piggyback contact lenses.
Topics: Administration, Topical; Animals; Anterior Chamber; Anti-Infective Agents; Contact Lenses, Hydrophilic; Cornea; Drug Delivery Systems; Drug Evaluation; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Polymers; Rabbits | 1996 |
Comparative in vitro activity of levofloxacin and ofloxacin against gram-positive bacteria.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacteria; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Molecular Sequence Data; Ofloxacin; Penicillins; Staphylococcus; Streptococcus; Vancomycin | 1996 |
Levofloxacin in vitro activity against bacteremic isolates of Streptococcus pneumoniae. Franklin County Pneumonia Study Group.
Topics: Anti-Infective Agents; Bacteremia; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Penicillins; Streptococcal Infections; Streptococcus pneumoniae | 1996 |
The comparative antimicrobial activity of levofloxacin tested against 350 clinical isolates of streptococci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Erythromycin; Lactams; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Streptococcus; Streptococcus pneumoniae; Time Factors; Vancomycin | 1996 |
Insufficient evidence of synergistic effect of levofloxacin and rifampin against Legionella pneumophila.
Topics: Anti-Infective Agents; Antibiotics, Antitubercular; Drug Synergism; Legionella pneumophila; Levofloxacin; Ofloxacin; Rifampin | 1996 |
Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Media; Culture Media, Serum-Free; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Metals; Microbial Sensitivity Tests; Microscopy, Electron; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Urine | 1996 |
Anaerobic activity of levofloxacin and metronidazole separately and in combination.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Drug Therapy, Combination; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Ofloxacin | 1996 |
Roxithromycin alone and in combination with either ethambutol or levofloxacin for disseminated Mycobacterium avium infections in beige mice.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacteremia; Colony Count, Microbial; Drug Combinations; Ethambutol; Levofloxacin; Mice; Mycobacterium avium; Ofloxacin; Roxithromycin; Spleen; Tuberculosis | 1996 |
Activities of bay Y 3118, levofloxacin, and ofloxacin alone or in combination with ethambutol against Mycobacterium avium complex in vitro, in human macrophages, and in beige mice.
Topics: Animals; Anti-Infective Agents; Cell Line; Drug Combinations; Ethambutol; Female; Fluoroquinolones; Humans; Levofloxacin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rats | 1996 |
Pharmacodynamics of once- or twice-daily levofloxacin versus vancomycin, with or without rifampin, against Staphylococcus aureus in an in vitro model with infected platelet-fibrin clots.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Blood Platelets; Colony Count, Microbial; Fibrin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Rifampin; Staphylococcus aureus; Vancomycin | 1996 |
Local absorption kinetics of levofloxacin from intestinal tract into portal vein in conscious rat using portal-venous concentration difference.
Topics: Animals; Electromagnetic Fields; Intestinal Absorption; Levofloxacin; Male; Ofloxacin; Portal Vein; Rats; Rats, Wistar | 1996 |
In-vitro activity of ofloxacin, levofloxacin and D-ofloxacin against staphylococci.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus; Staphylococcus aureus; Stereoisomerism | 1996 |
Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Clarithromycin; Erythromycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Streptococcus pneumoniae | 1996 |
Stability of levofloxacin in intravenous solutions in polyvinyl chloride bags.
Topics: Anti-Infective Agents; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Glucose; Humans; Infusions, Intravenous; Levofloxacin; Ofloxacin; Pharmaceutical Vehicles; Sodium Chloride; Solutions | 1996 |
Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clofazimine; Drug Combinations; Ethambutol; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Ofloxacin; Rifampin; Roxithromycin | 1996 |
In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains.
Topics: Acute Disease; Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Female; Kidney; Levofloxacin; Methicillin Resistance; Mice; Ofloxacin; Pyelonephritis; Staphylococcal Infections | 1996 |
In vitro susceptibility of anaerobes to quinolones in the United States.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Quinolones; United States | 1996 |
Effect of paclitaxel alone or in combination on the intracellular penetration and activity of quinolones in human neutrophils.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cisplatin; Doxorubicin; Fluoroquinolones; Humans; Levofloxacin; Neutrophils; Ofloxacin; Paclitaxel; Quinolones; Staphylococcus aureus | 1996 |
In-vitro activity of levofloxacin (l-ofloxacin), ofloxacin and ciprofloxacin against clinical isolates of Streptococcus pneumoniae obtained in England and Wales.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; England; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae; Wales | 1996 |
Comparative activities of new fluoroquinolones, alone or in combination with amoxicillin, trimethoprim-sulfamethoxazole, or rifampin, against intracellular Listeria monocytogenes.
Topics: Amoxicillin; Anti-Infective Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Fluoroquinolones; HeLa Cells; Humans; Levofloxacin; Listeria monocytogenes; Ofloxacin; Quinolones; Rifampin; Sulfamethoxazole; Trimethoprim | 1997 |
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin | 1996 |
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells].
Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature | 1996 |
In vitro susceptibility of penicillin-resistant Streptococcus pneumoniae to levofloxacin, selection of resistant mutants, and time-kill synergy studies of levofloxacin combined with vancomycin, teicoplanin, fusidic acid, and rifampin.
Topics: Anti-Bacterial Agents; Drug Synergism; Drug Therapy, Combination; Fusidic Acid; Levofloxacin; Mutation; Ofloxacin; Penicillin Resistance; Rifampin; Streptococcus pneumoniae; Teicoplanin; Vancomycin | 1996 |
In vivo oral efficacy of levofloxacin for treatment of systemic Pseudomonas aeruginosa infections in a murine model of septicemia.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Female; Levofloxacin; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 1996 |
Sparfloxacin and levofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Drug Eruptions; Fluoroquinolones; Gastrointestinal Diseases; Humans; Levofloxacin; Ofloxacin; Photosensitivity Disorders; Pneumonia; Quinolones | 1997 |
Evaluation of renal tubular secretion and reabsorption of levofloxacin in rats.
Topics: Animals; Anti-Infective Agents; Glomerular Filtration Rate; Kidney Tubules; Levofloxacin; Male; Ofloxacin; Rats; Rats, Wistar | 1997 |
Comparison of the postantibiotic and postantibiotic sub-MIC effects of levofloxacin and ciprofloxacin on Staphylococcus aureus and Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus; Streptococcus pneumoniae | 1997 |
Activities of levofloxacin, ofloxacin, and ciprofloxacin, alone and in combination with amikacin, against acinetobacters as determined by checkerboard and time-kill studies.
Topics: Acinetobacter; Amikacin; Anti-Infective Agents; Ciprofloxacin; Drug Combinations; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1997 |
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates.
Topics: Animals; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Cats; Ciprofloxacin; Dogs; Fluoroquinolones; Haplorhini; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Swine; Wound Infection | 1997 |
Assessment of the synergistic interactions of levofloxacin and ampicillin against Enterococcus faecium by the checkerboard agar dilution and time-kill methods.
Topics: Ampicillin; Ampicillin Resistance; Anti-Infective Agents; beta-Lactam Resistance; Drug Therapy, Combination; Enterococcus faecium; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillins | 1997 |
Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urine.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Stability; Humans; Levofloxacin; Linear Models; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Time Factors | 1997 |
Comparison of recalcitrance to ciprofloxacin and levofloxacin exhibited by Pseudomonas aeruginosa bofilms displaying rapid-transport characteristics.
Topics: Anti-Infective Agents; Biofilms; Biological Transport; Ciprofloxacin; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Spectroscopy, Fourier Transform Infrared | 1997 |
Susceptibility of multi-resistant Streptococcus pneumoniae to ciprofloxacin, ofloxacin and levofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1997 |
[A case of severe odontogenic infection with allergic skin reaction for beta-lactam antibiotics].
Topics: Adult; Anti-Bacterial Agents; Cellulitis; Cephalosporins; Clindamycin; Drug Eruptions; Drug Therapy, Combination; Female; Fosfomycin; Humans; Levofloxacin; Ofloxacin; Periapical Abscess | 1997 |
[Isolation rate of Enterococcus spp. from surgical infections and their susceptibilities].
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Enterococcus; Humans; Imipenem; Levofloxacin; Ofloxacin; Penicillins; Surgical Wound Infection; Thienamycins; Time Factors; Vancomycin | 1997 |
[Measurement of antibody titers to chlamydial infection and effects of levofloxacin in cystic cervicitis and chlamydial infection].
Topics: Actihaemyl; Administration, Oral; Adolescent; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bacterial; Chlamydia Infections; Chlamydia trachomatis; Chloramphenicol; Clarithromycin; Drug Therapy, Combination; Female; Humans; Immunoglobulin A; Immunoglobulin G; Levofloxacin; Middle Aged; Ofloxacin; Pessaries; Pregnancy; Pregnancy Complications, Infectious; Uterine Cervicitis | 1997 |
The bactericidal activity of levofloxacin compared with ofloxacin, D-ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Cefotaxime; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1997 |
Bacteriostatic and bactericidal activity of levofloxacin against Rickettsia rickettsii, Rickettsia conorii, 'Israeli spotted fever group rickettsia' and Coxiella burnetii.
Topics: Anti-Infective Agents; Colony Count, Microbial; Coxiella burnetii; Levofloxacin; Ofloxacin; Rickettsia; Rickettsia Infections; Rickettsia rickettsii | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
[Legionella pneumonia successfully treated despite late diagnosis].
Topics: Administration, Oral; Aged; Anti-Infective Agents; Cilastatin; Drug Combinations; Humans; Imipenem; Legionnaires' Disease; Levofloxacin; Male; Ofloxacin; Protease Inhibitors; Thienamycins | 1997 |
Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-susceptible or -resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Endocarditis, Bacterial; Floxacillin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1997 |
[Anti-Mycobacterium avium complex activities of KRM-1648, clarithromycin and levofloxacin in 7HSF medium at peak or average blood concentrations after their oral administration of clinical dosages].
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Clarithromycin; Culture Media; Humans; Levofloxacin; Mycobacterium avium Complex; Ofloxacin; Rifamycins | 1997 |
Transport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Epithelial Cells; Epithelium; Fluoroquinolones; Humans; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Quinolones; Swine | 1997 |
Mycobacterium marinum skin infection successfully treated with levofloxacin.
Topics: Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Ofloxacin; Remission Induction; Skin Diseases, Bacterial | 1997 |
[In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Clarithromycin; Diclofenac; Drug Therapy, Combination; Female; Levofloxacin; Mice; Mice, Inbred BALB C; Mycobacterium avium; Ofloxacin; Rifamycins; Tuberculosis | 1997 |
Susceptibility of twenty penicillin-susceptible and -resistant pneumococci to levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin by MIC and time-kill.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteriological Techniques; Ciprofloxacin; Clarithromycin; Drug Resistance, Microbial; Erythromycin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Sensitivity and Specificity; Species Specificity; Streptococcus pneumoniae | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
Comparative effects of levofloxacin and ofloxacin on the normal oral and intestinal microflora.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Bacteria; Feces; Female; Gram-Negative Bacteria; Humans; Intestines; Levofloxacin; Male; Middle Aged; Mouth; Ofloxacin; Saliva; Yeasts | 1997 |
Concentrations of levofloxacin (HR 355) in the respiratory tract following a single oral dose in patients undergoing fibre-optic bronchoscopy.
Topics: Administration, Oral; Anti-Infective Agents; Biopsy; Bronchoscopy; Female; Fiber Optic Technology; Humans; Levofloxacin; Lung; Male; Ofloxacin; Respiratory Tract Infections | 1997 |
In vitro activity of clarithromycin alone and in combination with ciprofloxacin or levofloxacin against Legionella spp.: enhanced effect by the addition of the metabolite 14-hydroxy clarithromycin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Humans; In Vitro Techniques; Legionella; Legionella pneumophila; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1997 |
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcal Infections; Streptococcus; Streptococcus pneumoniae | 1997 |
Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus | 1997 |
Effect of levofloxacin, erythromycin or rifampicin pretreatment on growth of Legionella pneumophila in human monocytes.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Erythromycin; Humans; Legionella pneumophila; Levofloxacin; Microbial Sensitivity Tests; Monocytes; Ofloxacin; Opsonin Proteins; Rifampin | 1997 |
In vitro antimicrobial activity of levofloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1997 |
Levofloxacin in the treatment of drug-resistant tuberculosis.
Topics: Aged; Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Levofloxacin; Male; Ofloxacin; Radiography; Tuberculosis, Multidrug-Resistant | 1997 |
Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season. The Laboratory Investigator Group.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Ceftriaxone; Cefuroxime; Clarithromycin; Cohort Studies; Drug Resistance, Microbial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Respiratory Tract Infections; Streptococcus pneumoniae; United States | 1997 |
Antimicrobial susceptibility of viridans group streptococci.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Clindamycin; Drug Resistance, Microbial; Gentamicins; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Rifampin; Streptococcal Infections; Streptococcus; Thienamycins; Vancomycin; Virginiamycin | 1997 |
Comparative activity of ciprofloxacin, ofloxacin, levofloxacin, and erythromycin against Legionella species by broth microdilution and intracellular susceptibility testing in HL-60 cells.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Erythromycin; HL-60 Cells; Humans; Legionella; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Reproducibility of Results | 1998 |
Lack of mutagenicity of levofloxacin in lacZ transgenic mice.
Topics: Animals; Bone Marrow; Ethylnitrosourea; Lac Operon; Levofloxacin; Liver; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Mutagens; Ofloxacin; Spermatozoa; Testis | 1998 |
Streptococcus pneumoniae killing rate and post-antibiotic effect of levofloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae; Time Factors | 1997 |
Levofloxacin for drug-resistant Mycobacterium tuberculosis.
Topics: Adult; Anti-Infective Agents; Drug Administration Schedule; Humans; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Multidrug-Resistant | 1998 |
Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages.
Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Female; Levofloxacin; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Phagocytosis; Rifamycins; Tuberculosis | 1998 |
Therapeutic effects of a new quinolone, DU-6859a, on polymicrobial infections in a newly designed model of rat uterine endometritis.
Topics: Animals; Anti-Infective Agents; Bacteroides fragilis; Disease Models, Animal; Drug Therapy, Combination; Endometritis; Escherichia coli; Female; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Rats; Rats, Sprague-Dawley | 1998 |
Sparfloxacin but not levofloxacin or ofloxacin prolongs cardiac repolarization in rabbit Purkinje fibers.
Topics: Action Potentials; Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Male; Ofloxacin; Purkinje Fibers; Quinolones; Rabbits; Stereoisomerism | 1998 |
Levofloxacin selects fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus less frequently than ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus | 1998 |
Timed kill kinetic studies of levofloxacin, ofloxacin, and ciprofloxacin against Moraxella catarrhalis.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Levofloxacin; Moraxella catarrhalis; Neisseriaceae; Ofloxacin; Piperazines; Time Factors | 1998 |
In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Streptococcus pneumoniae | 1998 |
Determination of activities of levofloxacin, alone and combined with gentamicin, ceftazidime, cefpirome, and meropenem, against 124 strains of Pseudomonas aeruginosa by checkerboard and time-kill methodology.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Thienamycins; Time Factors | 1998 |
In vitro activity of levofloxacin against a selected group of anaerobic bacteria isolated from skin and soft tissue infections.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Colony Count, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Skin Diseases, Infectious; Soft Tissue Infections | 1998 |
New quinolones, ofloxacin and levofloxacin, inhibit telomerase activity in transitional cell carcinoma cell lines.
Topics: Anti-Infective Agents; Bromodeoxyuridine; Carcinoma, Transitional Cell; Cell Cycle; DNA, Neoplasm; Humans; Levofloxacin; Ofloxacin; Telomerase; Tumor Cells, Cultured | 1997 |
Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest.
Topics: Anti-Infective Agents; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1998 |
Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens.
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Bites and Stings; Bites, Human; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Species Specificity; Wound Infection | 1998 |
Levofloxacin population pharmacokinetics and creation of a demographic model for prediction of individual drug clearance in patients with serious community-acquired infection.
Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Female; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Ofloxacin | 1998 |
Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Erythromycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1998 |
Oral quinolone in the treatment of experimental polymicrobial puerperal infection in rabbits.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Female; Levofloxacin; Ofloxacin; Pregnancy; Puerperal Infection; Rabbits | 1998 |
Concentration of levofloxacin in cervical mucus and its clinical effects on cervicitis.
Topics: Adult; Anti-Infective Agents; Cervix Mucus; Chlamydia trachomatis; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Uterine Cervicitis | 1997 |
In vitro and in vivo activities of levofloxacin against biofilm-producing Pseudomonas aeruginosa.
Topics: Alginates; Animals; Anti-Infective Agents; Biofilms; Female; Glucuronic Acid; Guinea Pigs; Hexuronic Acids; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Permeability; Pneumonia, Bacterial; Polytetrafluoroethylene; Pseudomonas aeruginosa; Pseudomonas Infections | 1998 |
A comparison of the activity of ciprofloxacin and levofloxacin with other agents against respiratory tract pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Haemophilus influenzae; Humans; Levofloxacin; Moraxella catarrhalis; Ofloxacin; Respiratory Tract Infections; Streptococcus pneumoniae | 1998 |
Successful treatment of murine listeriosis and salmonellosis with levofloxacin.
Topics: Animals; Anti-Infective Agents; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Levofloxacin; Listeria monocytogenes; Listeriosis; Mice; Ofloxacin; Penicillins; Salmonella Infections, Animal; Salmonella typhimurium | 1998 |
[Evaluation of in vitro activity of ofloxacin against 73 strains of Chlamydia trachomatis isolated from gynecologic infections].
Topics: Anti-Infective Agents; Chlamydia trachomatis; Evaluation Studies as Topic; Female; Genital Diseases, Female; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Species Specificity | 1998 |
Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC-PK1.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Anti-Infective Agents; Cyclosporine; Epithelial Cells; Fluoroquinolones; Hydrogen-Ion Concentration; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Piperazines; Quinolones; Swine | 1998 |
Antipneumococcal activities of levofloxacin and clarithromycin as determined by agar dilution, microdilution, E-test, and disk diffusion methodologies.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Carbon Dioxide; Clarithromycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1998 |
In vitro susceptibility of recent gram-positive isolates to ciprofloxacin, levofloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin | 1998 |
Fluoroquinolone-resistant Moraxella catarrhalis in a patient with pneumonia: report from the SENTRY Antimicrobial Surveillance Program (1998).
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Immunocompromised Host; Levofloxacin; Male; Microbial Sensitivity Tests; Moraxella catarrhalis; Neisseriaceae Infections; Ofloxacin; Pneumonia, Bacterial; Population Surveillance | 1998 |
In vitro activity of quinupristin/dalfopristin and newer quinolones combined with gentamicin against resistant isolates of Enterococcus faecalis and Enterococcus faecium.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gentamicins; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Virginiamycin | 1998 |
Antibacterial effects of levofloxacin, erythromycin, and rifampin in a human monocyte system against Legionella pneumophila.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Colony Count, Microbial; Drug Therapy, Combination; Erythromycin; Humans; In Vitro Techniques; Legionella pneumophila; Levofloxacin; Monocytes; Ofloxacin; Rifampin | 1998 |
Effects of sucrose and silver on Staphylococcus aureus biofilms.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Bacterial Adhesion; Biofilms; Blood Coagulation; Colony Count, Microbial; Culture Media; Furunculosis; Humans; Impetigo; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Silver Sulfadiazine; Staphylococcal Infections; Staphylococcus aureus; Sucrose | 1998 |
Comparative in-vitro activity of levofloxacin against Chlamydia spp.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia; Chlamydia Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tetracyclines | 1998 |
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature | 1999 |
Mechanism underlying levofloxacin uptake by human polymorphonuclear neutrophils.
Topics: Anti-Infective Agents; Calcium; Chelating Agents; Humans; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Neutrophils; Ofloxacin; Probenecid; Protein Kinase Inhibitors; Temperature | 1999 |
Activities of newer fluoroquinolones against Streptococcus pneumoniae clinical isolates including those with mutations in the gyrA, parC, and parE loci.
Topics: Anti-Infective Agents; Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ofloxacin; Streptococcus pneumoniae | 1999 |
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Bacterial Proteins; Biological Transport; Ciprofloxacin; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 1999 |
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin | 1999 |
Italian survey on comparative levofloxacin susceptibility in 334 clinical isolates of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Intensive Care Units; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 1999 |
Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess.
Topics: Abscess; Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Female; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Staphylococcal Skin Infections | 1999 |
Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection.
Topics: Ampicillin; Ampicillin Resistance; Anti-Infective Agents; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Penicillins; Pneumococcal Infections | 1999 |
In vitro activity of ciprofloxacin, ofloxacin, and levofloxacin against Micrococcus species and Stomatococcus mucilaginosus isolated from healthy subjects and neutropenic patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Micrococcus; Neutropenia; Ofloxacin | 1998 |
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Buffers; Carrier Proteins; Cells, Cultured; Hydrogen-Ion Concentration; Levofloxacin; Membrane Proteins; Ofloxacin; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Potassium; Rats; Tetraethylammonium; Transfection; Xenopus laevis | 1999 |
In vitro activity of ciprofloxacin, levofloxacin, and trovafloxacin, alone and in combination with beta-lactams, against clinical isolates of Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Burkholderia cepacia.
Topics: Anti-Infective Agents; beta-Lactams; Burkholderia cepacia; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Pseudomonas aeruginosa; Xanthomonas | 1999 |
In vitro activities of ketolides HMR 3647 [correction of HRM 3647] and HMR 3004 [correction of HRM 3004], levofloxacin, and other quinolones and macrolides against Neisseria spp. and Moraxella catarrhalis.
Topics: Anti-Bacterial Agents; Humans; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Neisseria; Ofloxacin | 1999 |
Predictors for multidrug-resistant tuberculosis among HIV-infected patients and response to specific drug regimens. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Trials Group (ACTG), National Institutes for Hea
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Chi-Square Distribution; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Levofloxacin; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pilot Projects; Prospective Studies; Risk Factors; Survival Analysis; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; United States | 1999 |
The bactericidal activity of levofloxacin against ampicillin-resistant and ampicillin-susceptible Haemophilus influenzae in comparison with ofloxacin, ciprofloxacin and sparfloxacin.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 1999 |
The antibacterial efficacy of levofloxacin and ciprofloxacin against Pseudomonas aeruginosa assessed by combining antibiotic exposure and bacterial susceptibility.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 1999 |
A reverse-phase, isocratic high-performance liquid chromatography assay for levofloxacin.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Levofloxacin; Ofloxacin | 1999 |
Distribution characteristics of levofloxacin and grepafloxacin in rat kidney.
Topics: Animals; Anti-Infective Agents; Carbon Radioisotopes; Cimetidine; Dose-Response Relationship, Drug; Fluoroquinolones; In Vitro Techniques; Kidney Cortex; Kinetics; Levofloxacin; Male; Ofloxacin; p-Aminohippuric Acid; Piperazines; Rats; Rats, Wistar; Tetraethylammonium; Tissue Distribution | 1999 |
Primary Shewanella alga septicemia in a patient on hemodialysis.
Topics: Anti-Bacterial Agents; Bacteremia; Cefazolin; Drug Therapy, Combination; Escherichia coli; Female; Gentamicins; Gram-Negative Bacterial Infections; Gram-Negative Facultatively Anaerobic Rods; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Renal Dialysis | 1999 |
Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Levofloxacin; Mutation; Ofloxacin; Operon; Pseudomonas aeruginosa | 1999 |
Pharmacodynamics of levofloxacin and ciprofloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Dose-Response Relationship, Drug; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Penicillin Resistance; Streptococcus pneumoniae | 1999 |
Anti-pneumococcal activity of gatifloxacin compared with other quinolone and non-quinolone agents.
Topics: Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Streptococcus pneumoniae | 1999 |
Antibacterial activity of moxifloxacin (Bay 12-8039) against aerobic clinical isolates, and provisional criteria for disk susceptibility tests.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria, Aerobic; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 1999 |
Prophylaxis of local vascular graft infection with levofloxacin incorporated into albumin-sealed dacron graft (LVFX-ALB Graft).
Topics: Albumins; Animals; Anti-Infective Agents; Bacterial Adhesion; Blood Vessel Prosthesis Implantation; Colony Count, Microbial; Disease Models, Animal; Dogs; Humans; Levofloxacin; Ofloxacin; Polyethylene Terephthalates; Rabbits; Staphylococcal Infections | 1999 |
[Levofloxacin-induced neurological adverse effects such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients].
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Dyskinesia, Drug-Induced; Hallucinations; Humans; Levofloxacin; Male; Ofloxacin; Respiratory Tract Infections; Seizures | 1999 |
The susceptibility of Streptococcus pneumoniae to levofloxacin and other antibiotics.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1999 |
A comparative study of the in-vitro activity of levofloxacin against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 1999 |
In-vitro bacteriostatic activity of levofloxacin and three other fluoroquinolones against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Streptococcus pneumoniae | 1999 |
In-vitro activity of levofloxacin against Streptococcus pneumoniae with various levels of penicillin resistance.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Child; Humans; Lactams; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae | 1999 |
In-vitro activity of levofloxacin, a new fluoroquinolone: evaluation against Haemophilus influenzae and Moraxella catarrhalis.
Topics: Anti-Infective Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Pefloxacin | 1999 |
In-vitro activity of levofloxacin, ofloxacin and D-ofloxacin against coryneform bacteria and Listeria monocytogenes.
Topics: Anti-Infective Agents; Brevibacterium; Corynebacterium; Humans; Levofloxacin; Listeria monocytogenes; Microbial Sensitivity Tests; Ofloxacin | 1999 |
Comparative in-vitro activity of levofloxacin, other fluoroquinolones, doxycycline and erythromycin against Ureaplasma urealyticum and Mycoplasma hominis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Erythromycin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycoplasma hominis; Ofloxacin; Ureaplasma urealyticum | 1999 |
Comparative in-vitro activity of levofloxacin against isolates of bacteria from adult patients with community-acquired lower respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Bronchitis; Chronic Disease; Community-Acquired Infections; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Pneumonia, Bacterial; Pseudomonas aeruginosa; Streptococcus pneumoniae | 1999 |
In-vitro antibacterial activity of levofloxacin against hospital isolates: a multicentre study.
Topics: Acinetobacter; Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Hospitals, University; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas | 1999 |
Susceptibility to levofloxacin of clinical isolates of bacteria from intensive care and haematology/oncology patients in Switzerland: a multicentre study.
Topics: Anti-Infective Agents; Bacteria; Hematologic Diseases; Hospital Units; Humans; Intensive Care Units; Levofloxacin; Microbial Sensitivity Tests; Neoplasms; Ofloxacin; Prospective Studies; Switzerland | 1999 |
Relative potential for selection of fluoroquinolone-resistant Streptococcus pneumoniae strains by levofloxacin: comparison with ciprofloxacin, sparfloxacin and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 1999 |
Serum bactericidal activity of levofloxacin against Streptococcus pneumoniae.
Topics: Adult; Anti-Infective Agents; Cefotaxime; Cephalosporins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Serum Bactericidal Test; Streptococcus pneumoniae | 1999 |
Levofloxacin: serum bactericidal activity against methicillin-resistant Staphylococcus aureus isolates.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Serum Bactericidal Test; Staphylococcus aureus | 1999 |
Bactericidal activity of levofloxacin against Streptococcus pneumoniae in an in-vitro model simulating serum pharmacokinetic parameters.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Penicillin Resistance; Serum Bactericidal Test; Streptococcus pneumoniae | 1999 |
Pharmacodynamics of levofloxacin and ofloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 1999 |
Comparative efficacies of levofloxacin and ciprofloxacin against Streptococcus pneumoniae in a mouse model of experimental septicaemia.
Topics: Acute Kidney Injury; Administration, Cutaneous; Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Humans; Lethal Dose 50; Levofloxacin; Mice; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; Survival Analysis; Time Factors; Uranyl Nitrate | 1999 |
Selection of resistant variants of respiratory pathogens by quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Nalidixic Acid; Ofloxacin; Pneumonia, Bacterial; Streptococcus pneumoniae | 1999 |
Compatibility of levofloxacin with 34 medications during simulated Y-site administration.
Topics: Anti-Infective Agents; Drug Incompatibility; Humans; Injections, Intravenous; Levofloxacin; Ofloxacin | 1999 |
Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.
Topics: Adrenergic Uptake Inhibitors; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Reserpine; Staphylococcus aureus; Topoisomerase II Inhibitors | 1999 |
Contribution of topoisomerase IV and DNA gyrase mutations in Streptococcus pneumoniae to resistance to novel fluoroquinolones.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Phenotype; Streptococcus pneumoniae; Transformation, Bacterial | 1999 |
In vitro antibacterial activity of LJC 11,036, an active metabolite of L-084, a new oral carbapenem antibiotic with potent antipneumococcal activity.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Carrier Proteins; Cefdinir; Cephalosporins; Dipeptidases; Drug Stability; Escherichia coli Proteins; Hexosyltransferases; Imipenem; Lactams; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Ofloxacin; Penicillin-Binding Proteins; Peptidoglycan Glycosyltransferase; Peptidyl Transferases; Protein Binding; Serine-Type D-Ala-D-Ala Carboxypeptidase; Thienamycins | 1999 |
Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterat
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Enterobacter cloacae; Fluoroquinolones; Gatifloxacin; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines | 1999 |
Genotypic evolution in a quinolone-resistant Neisseria gonorrhoeae isolate from a patient with clinical failure of levofloxacin treatment.
Topics: Adult; Anti-Infective Agents; Chromosomes, Bacterial; DNA, Bacterial; Drug Resistance, Microbial; Genotype; Gonorrhea; Humans; Levofloxacin; Male; Neisseria gonorrhoeae; Ofloxacin; Polymerase Chain Reaction; Quinolones; Treatment Outcome | 1999 |
Stereoselective permeation of new fluorinated quinolone derivatives across LLC-PK1 cell monolayers.
Topics: Animals; Anti-Infective Agents; Biological Transport; Cations; Cell Membrane Permeability; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Guanidine; Kidney; Levofloxacin; LLC-PK1 Cells; Mannitol; Ofloxacin; Stereoisomerism; Swine; Tritium | 1999 |
Cultured rabbit corneal epithelium elicits levofloxacin absorption and secretion.
Topics: Absorption; Animals; Anti-Infective Agents; Cell Line; Dose-Response Relationship, Drug; Epithelium, Corneal; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Ofloxacin; Rabbits; Stereoisomerism; Temperature; Time Factors | 1999 |
Characterization of the carrier-mediated transport of levofloxacin, a fluoroquinolone antimicrobial agent, in rabbit cornea.
Topics: Animals; Anti-Infective Agents; Biological Transport; Carrier Proteins; Cornea; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Levofloxacin; Male; Ofloxacin; Permeability; Rabbits; Temperature | 1999 |
[MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins | 1999 |
Molecular cloning of the gyrA and gyrB genes of Bacteroides fragilis encoding DNA gyrase.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacteroides fragilis; Base Sequence; Cloning, Molecular; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ofloxacin; Recombinant Proteins; Sequence Homology, Amino Acid | 1999 |
Bactericidal activity and postantibiotic effect of levofloxacin against anaerobes.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacteroides; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Time Factors | 1999 |
The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Multidrug Resistance-Associated Proteins; Norfloxacin; Ofloxacin; Omeprazole; Species Specificity; Staphylococcal Infections; Staphylococcus aureus | 1999 |
Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus.
Topics: Animals; Aortic Valve; Drug Resistance, Microbial; Endocarditis, Bacterial; Heart Valve Diseases; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus sanguis | 1999 |
QTC interval prolongation and polymorphic ventricular tachycardia in association with levofloxacin.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Electrocardiography; Female; Heart Conduction System; Humans; Levofloxacin; Long QT Syndrome; Ofloxacin; Tachycardia, Ventricular | 1999 |
Stability of levofloxacin in an extemporaneously compounded oral liquid.
Topics: Anti-Infective Agents; Drug Compounding; Drug Stability; Levofloxacin; Ofloxacin | 1999 |
Comparative in vitro antimicrobial activities of the newly synthesized quinolone HSR-903, sitafloxacin (DU-6859a), gatifloxacin (AM-1155), and levofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1999 |
Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Carrier Proteins; Dipeptides; Drug Resistance, Microbial; Drug Stability; Drug Synergism; Endopeptidases; Gene Expression; Levofloxacin; Membrane Transport Proteins; Molecular Structure; Ofloxacin; Ornithine; Pseudomonas aeruginosa; Structure-Activity Relationship | 1999 |
Fatal meningitis due to levofloxacin-resistant Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Fatal Outcome; Humans; Levofloxacin; Male; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 1999 |
Efficacy of levofloxacin in the treatment of experimental endocarditis caused by viridans group streptococci.
Topics: Animals; Anti-Infective Agents; Catheterization; Ceftriaxone; Ciprofloxacin; Endocarditis, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Rats; Streptococcal Infections; Streptococcus; Streptococcus sanguis; Treatment Outcome | 1999 |
Rhodococcus equi nosocomial meningitis cured by levofloxacin and shunt removal.
Topics: Actinomycetales Infections; Anti-Infective Agents; Cross Infection; Female; Humans; Levofloxacin; Meningitis, Bacterial; Middle Aged; Ofloxacin; Rhodococcus equi; Ventriculoperitoneal Shunt | 2000 |
Levofloxacin in vitro activity and time-kill evaluation of Stenotrophomonas maltophilia clinical isolates.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Stenotrophomonas maltophilia; Time Factors | 2000 |
Comparative antimicrobial activities of the newly synthesized quinolone WQ-3034, levofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: 4-Quinolones; Aminopyridines; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Rifamycins | 2000 |
[Levofloxacin concentrations in serum, sputum and lung tissue: evaluation of its efficacy according to breakpoint].
Topics: Adult; Aged; Chronic Disease; Female; Humans; Levofloxacin; Lung; Male; Middle Aged; Ofloxacin; Pneumonia; Respiratory Tract Infections; Saliva; Time Factors | 1999 |
Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model.
Topics: Anti-Infective Agents; Blood Coagulation; Ciprofloxacin; Fibrin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae | 2000 |
Comparative activities of ciprofloxacin and levofloxacin against Streptococcus pneumoniae in an In vitro dynamic model.
Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Humans; Levofloxacin; Ofloxacin; Streptococcus pneumoniae | 2000 |
Action of quinolones against Staphylococcus aureus topoisomerase IV: basis for DNA cleavage enhancement.
Topics: Anti-Infective Agents; Catalysis; Ciprofloxacin; DNA; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Naphthyridines; Ofloxacin; Staphylococcus aureus; Topoisomerase II Inhibitors | 2000 |
Outcomes of patients with multidrug-resistant pulmonary tuberculosis treated with ofloxacin/levofloxacin-containing regimens.
Topics: Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Female; Hong Kong; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Recurrence; Retrospective Studies; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2000 |
Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms.
Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines | 2000 |
Bactericidal activity of levofloxacin and ciprofloxacin on clinical isolates of different phenotypes of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2000 |
[In vitro activities of levofloxacin and other antibiotics against fresh clinical isolates].
Topics: Ampicillin; Anti-Infective Agents; Bacteria; Bacterial Infections; Cefaclor; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Humans; Levofloxacin; Methicillin; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillins | 1999 |
Levofloxacin penetrates human monocytes and enhances intracellular killing of Staphylococcus aureus and Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Blood Bactericidal Activity; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Levofloxacin; Monocytes; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus; Temperature | 2000 |
Endothelial cell compatibility of trovafloxacin and levofloxacin for intravenous use.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anti-Infective Agents; Cell Survival; Chromatography, High Pressure Liquid; Culture Media; Endothelium, Vascular; Female; Fluoroquinolones; Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Levofloxacin; Naphthyridines; Ofloxacin; Pregnancy; Umbilical Veins | 2000 |
Transepithelial transport of levofloxacin in the isolated perfused rat kidney.
Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biological Transport; Carbon Radioisotopes; Cimetidine; Coloring Agents; Enzyme Inhibitors; Epithelial Cells; Evans Blue; Fluoroquinolones; In Vitro Techniques; Inulin; Kidney; Levofloxacin; Male; Ofloxacin; p-Aminohippuric Acid; Perfusion; Piperazines; Rats; Rats, Wistar; Tetraethylammonium; Urine | 2000 |
Pharmacokinetics and pharmacodynamics of levofloxacin against Streptococcus pneumoniae and Staphylococcus aureus in human skin blister fluid.
Topics: Anti-Infective Agents; Blister; Body Fluids; Granulocytes; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Skin Diseases, Bacterial; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors | 2000 |
Mechanism of histamine release induced by levofloxacin, a fluoroquinolone antibacterial agent.
Topics: Animals; Anti-Infective Agents; Benzalkonium Compounds; Calcium; GTP-Binding Proteins; Histamine Release; Hydrogen-Ion Concentration; Levofloxacin; Male; Neuraminidase; Ofloxacin; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Temperature; Virulence Factors, Bordetella | 2000 |
[Levofloxacin-induced tendinitis].
Topics: Anti-Infective Agents, Urinary; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tendinopathy | 2000 |
Oral levofloxacin in the treatment of community-acquired pneumonia.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Community-Acquired Infections; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial | 2000 |
Effect of antibiotics, levofloxacin and fosfomycin, on a mouse model with Escherichia coli O157 infection.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Toxins; Diarrhea; Disease Models, Animal; Escherichia coli Infections; Escherichia coli O157; Feces; Fosfomycin; Germ-Free Life; Humans; Levofloxacin; Mice; Ofloxacin; Shiga Toxins; Treatment Outcome | 2000 |
Microbiological efficacy of levofloxacin for treatment of community-acquired pneumonia due to Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydia Infections; Chlamydophila pneumoniae; Community-Acquired Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Outcome Assessment, Health Care; Pneumonia, Bacterial | 2000 |
Comparative in vitro activity of vancomycin and levofloxacin in combination with rifampin against planktonic versus sessile cells of Staphylococcus epidermidis.
Topics: Drug Therapy, Combination; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; Staphylococcus epidermidis; Vancomycin | 2000 |
Macrolides and clindamycin suppress the release of Shiga-like toxins from Escherichia coli O157:H7 in vitro.
Topics: Animals; Anti-Bacterial Agents; Bacterial Toxins; Cefdinir; Cephalosporins; Chlorocebus aethiops; Clindamycin; Dose-Response Relationship, Drug; Escherichia coli O157; Fosfomycin; Humans; Latex Fixation Tests; Levofloxacin; Microbial Sensitivity Tests; Miocamycin; Ofloxacin; Roxithromycin; Shiga Toxin 1; Shiga Toxin 2; Time Factors; Vero Cells | 2000 |
Comparative activities of telithromycin (HMR 3647), levofloxacin, and other antimicrobial agents against human mycoplasmas.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma Infections; Ofloxacin | 2000 |
Characterization of histamine release induced by fluoroquinolone antibacterial agents in-vivo and in-vitro.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dogs; Female; Histamine Release; Levofloxacin; Male; Mast Cells; Ofloxacin; Rats; Rats, Sprague-Dawley; Species Specificity | 2000 |
[Fibrosing alveolitis following Legionella pneumonia].
Topics: Anti-Inflammatory Agents; Clarithromycin; Drug Therapy, Combination; Humans; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Minocycline; Ofloxacin; Pulmonary Fibrosis; Pulse Therapy, Drug; Steroids; Treatment Outcome | 2000 |
Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila.
Topics: Anti-Bacterial Agents; Erythromycin; Humans; Ketolides; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Macrolides; Monocytes; Ofloxacin | 2000 |
Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation.
Topics: Animals; Biofilms; Chronic Disease; Clarithromycin; Disease Models, Animal; Drug Therapy, Combination; Intubation; Levofloxacin; Male; Mice; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections | 2000 |
Antimycobacterial activities of novel levofloxacin analogues.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Ofloxacin; Structure-Activity Relationship | 2000 |
Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains.
Topics: Acinetobacter; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines | 2000 |
Quinolone drug rash in a patient with infectious mononucleosis.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Drug Eruptions; Female; Follow-Up Studies; Humans; Infectious Mononucleosis; Levofloxacin; Ofloxacin | 2000 |
[Levofloxacin-induced eosinophilic pneumonia complicated by bronchial asthma].
Topics: Aged; Anti-Infective Agents; Asthma; Female; Humans; Levofloxacin; Ofloxacin; Pulmonary Eosinophilia | 2000 |
Uptake and intracellular activity of ofloxacin isomers in human phagocytic and non-phagocytic cells.
Topics: Anti-Infective Agents; Cells, Cultured; Epithelial Cells; Humans; Isomerism; Levofloxacin; Macrophages, Peritoneal; Neutrophils; Ofloxacin; Staphylococcus aureus | 2000 |
Pharmacokinetics of ofloxacin enantiomers after intravenous administration for antibiotic prophylaxis in biliary surgery.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Cholecystectomy; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Stereoisomerism | 2000 |
Activities of antimicrobial agents against intracellular pneumococci.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Fluoroquinolones; Gentamicins; Humans; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Penicillin G; Quinolines; Rifampin; Streptococcus pneumoniae; Tumor Cells, Cultured | 2000 |
[Activities of antimicrobial agents against 5,180 clinical isolates obtained from 26 medical institutions during 1998 in Japan. Levofloxacin--Surveillance Group].
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Respiratory Tract Infections; Urinary Tract Infections | 2000 |
In vitro characterization of fluoroquinolone concentration/MIC antimicrobial activity and resistance while simulating clinical pharmacokinetics of levofloxacin, ofloxacin, or ciprofloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Microbial; Levofloxacin; Logistic Models; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Streptococcus pneumoniae | 2000 |
Compatibility and stability of linezolid injection admixed with three quinolone antibiotics.
Topics: Acetamides; Anti-Infective Agents; Ciprofloxacin; Drug Stability; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones | 2000 |
Bacteremic pneumonia due to multidrug-resistant pneumococci in 3 patients treated unsuccessfully with azithromycin and successfully with levofloxacin.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteremia; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2000 |
Levofloxacin-resistant pneumococcus.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 2000 |
Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line caco-2.
Topics: Anti-Infective Agents; Biological Transport; Caco-2 Cells; Cyclosporine; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Intestinal Mucosa; Levofloxacin; Metabolic Clearance Rate; Ofloxacin; Piperazines | 2000 |
[Antibacterial activity of fosfomycin against the causative bacteria isolated from bacterial enteritis].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Blood; Campylobacter; Electrolytes; Enteritis; Escherichia coli; Escherichia coli O157; Fosfomycin; Humans; Hydrogen-Ion Concentration; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Salmonella; Shigella | 2000 |
Levofloxacin use at an academic teaching institution.
Topics: Anti-Infective Agents; Drug Utilization Review; Hospitals, Teaching; Humans; Levofloxacin; Massachusetts; Ofloxacin | 2000 |
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin | 2000 |
Activities of clinafloxacin, gatifloxacin, gemifloxacin, and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Streptococcus pneumoniae | 2000 |
A comparative In vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America. The Gemifloxacin Surveillance Study Research Group.
Topics: Adolescent; Adult; Anti-Infective Agents; Drug Resistance, Microbial; Europe; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Naphthyridines; North America; Ofloxacin; South America; Streptococcus pneumoniae | 2000 |
Comparative pharmacodynamics of moxifloxacin and levofloxacin in an in vitro dynamic model: prediction of the equivalent AUC/MIC breakpoints and equiefficient doses.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Escherichia coli; Fluoroquinolones; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2000 |
Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Community-Acquired Infections; Drug Resistance, Microbial; Erythromycin; Gram-Positive Bacteria; Humans; Japan; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Respiratory Tract Infections; Staphylococcus aureus | 2000 |
In vivo activity of levofloxacin alone or in combination with imipenem or amikacin in a mouse model of Acinetobacter baumannii pneumonia.
Topics: Acinetobacter Infections; Amikacin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Drug Therapy, Combination; Female; Imipenem; Levofloxacin; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Bacterial; Thienamycins | 2000 |
The emergence of resistance to levofloxacin before clinical use in a university hospital in Singapore.
Topics: Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 2000 |
Terbium-sensitized luminescence determination of levofloxacin in tablets and human urine and serum.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Luminescence; Ofloxacin; Tablets; Terbium | 2000 |
Levofloxacin-induced allergic interstitial nephritis.
Topics: Aged; Anti-Infective Agents; Humans; Levofloxacin; Male; Nephritis, Interstitial; Ofloxacin | 2000 |
Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades.
Topics: Action Potentials; Animals; Anti-Infective Agents; Dogs; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart; Heart Block; Levofloxacin; Long QT Syndrome; Male; Models, Animal; Ofloxacin; Torsades de Pointes; Ventricular Dysfunction, Right | 2000 |
Experiences at a large teaching hospital with levofloxacin for the treatment of community-acquired pneumonia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Community-Acquired Infections; Costs and Cost Analysis; Diagnosis-Related Groups; Drug Costs; Female; Hospitalization; Humans; Injections, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia; Practice Guidelines as Topic; Retrospective Studies; Treatment Outcome | 2000 |
Use of a physician order entry system to identify opportunities for intravenous to oral levofloxacin conversion.
Topics: Administration, Oral; Anti-Infective Agents; Clinical Pharmacy Information Systems; Drug Prescriptions; Drug Therapy, Computer-Assisted; Humans; Injections, Intravenous; Levofloxacin; Medication Systems, Hospital; Ofloxacin; Practice Guidelines as Topic; Seasons | 2000 |
Approaches to drug therapy, formulary, and pathway management in a large community hospital.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Community-Acquired Infections; Cost-Benefit Analysis; Critical Pathways; Disease Management; Drug Costs; Drug Therapy, Computer-Assisted; Formularies, Hospital as Topic; Hospitals, Community; Humans; Indiana; Injections, Intravenous; Length of Stay; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pharmacy Service, Hospital; Pneumonia; Seasons; Treatment Outcome | 2000 |
Recurrent penicillin-resistant pneumococcal sepsis after matched unrelated donor (MUD) transplantation for refractory T cell lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Transplantation; Carmustine; Cefotaxime; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Idarubicin; Immunocompromised Host; Immunosuppressive Agents; Levofloxacin; Lymphoma, T-Cell; Male; Melphalan; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Prednisone; Recurrence; Rifampin; Splenectomy; Streptococcus pneumoniae; Transplantation Conditioning; Vincristine | 2000 |
The use of Monte Carlo simulation to examine pharmacodynamic variance of drugs: fluoroquinolone pharmacodynamics against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Monte Carlo Method; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2000 |
Anti-anaerobic activity of levofloxacin alone and combined with clindamycin and metronidazole.
Topics: Anti-Bacterial Agents; Bacteremia; Bacteria, Anaerobic; Clindamycin; Drug Combinations; Drug Synergism; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Ofloxacin | 2000 |
Inhibitory effects of the quinolone antibiotics trovafloxacin, ciprofloxacin, and levofloxacin on osteoblastic cells in vitro.
Topics: Animals; Anti-Infective Agents; Bromodeoxyuridine; Calcification, Physiologic; Cell Count; Cell Division; Cells, Cultured; Ciprofloxacin; Dose-Response Relationship, Drug; Extracellular Matrix; Fluoroquinolones; Levofloxacin; Mice; Naphthyridines; Ofloxacin; Osteoblasts | 2000 |
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Carrier Proteins; Cephalosporins; Dipeptides; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Levofloxacin; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Plasmids; Pseudomonas aeruginosa | 2001 |
Anaphylactoid reaction to levofloxacin.
Topics: Anaphylaxis; Anti-Infective Agents; Drug Hypersensitivity; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin | 2000 |
Efficacy of rifampin-levofloxacin as a prophylactic agent in preventing Staphylococcus epidermidis graft infection.
Topics: Animals; Blood Vessel Prosthesis; Humans; Levofloxacin; Male; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Prosthesis-Related Infections; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis | 2000 |
Choice of antibiotic and risk of colonization with vancomycin-resistant Enterococcus among patients admitted for treatment of community-acquired pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Enterococcus; Erythromycin; Female; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Risk Factors; Vancomycin Resistance | 2000 |
[Resistance and new antibiotic strategies. The other new molecules].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Lactams; Levofloxacin; Neutropenia; Ofloxacin; Peptides; Pneumococcal Infections | 2000 |
Antimicrobial resistance of Streptococcus pneumoniae isolates in 1999 and 2000 in Madrid, Spain: a multicentre surveillance study.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Spain; Streptococcus pneumoniae | 2001 |
In vivo synergy between green tea extract and levofloxacin against enterohemorrhagic Escherichia coli O157 infection.
Topics: Animals; Anti-Infective Agents; Catechin; Colony Count, Microbial; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Escherichia coli Infections; Escherichia coli O157; Feces; Female; Germ-Free Life; Levofloxacin; Male; Mice; Mice, Inbred ICR; Ofloxacin; Plant Extracts; Shiga Toxin; Tea | 2001 |
Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin: case report.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Humans; Injections, Spinal; Levofloxacin; Male; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant | 2001 |
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae; Time Factors | 2001 |
Streptococcus pneumoniae response to repeated moxifloxacin or levofloxacin exposure in a rabbit tissue cage model.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Disease Models, Animal; Female; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Rabbits; Streptococcus pneumoniae | 2001 |
Phenotypic resistance of Staphylococcus aureus, selected Enterobacteriaceae, and Pseudomonas aeruginosa after single and multiple in vitro exposures to ciprofloxacin, levofloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Phenotype; Pseudomonas aeruginosa; Regression Analysis; Reproducibility of Results; Staphylococcus aureus | 2001 |
Macrolide and fluoroquinolone (levofloxacin) resistances among Streptococcus pneumoniae strains: significant trends from the SENTRY Antimicrobial Surveillance Program (North America, 1997-1999).
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Macrolides; North America; Ofloxacin; Pneumococcal Infections; Population Surveillance; Streptococcus pneumoniae | 2000 |
Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
Topics: Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins; Tuberculosis | 2000 |
[A Shigella sonnei outbreak in Nagasaki].
Topics: Anti-Infective Agents; Disease Outbreaks; Dysentery, Bacillary; Humans; Japan; Levofloxacin; Ofloxacin; Shigella sonnei | 2000 |
[Pharma-clinics. The drug of the month. Levofloxacin (Tavanic)].
Topics: Acute Disease; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Bronchitis; Community-Acquired Infections; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Sinusitis; Urinary Tract Infections | 2000 |
[levofloxacin and behavior disorder in a patient admitted to intensive care].
Topics: Anti-Infective Agents; Critical Care; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Psychoses, Substance-Induced | 2000 |
Severe lithium toxicity induced by combined levofloxacin administration.
Topics: Bipolar Disorder; Creatinine; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Humans; Levofloxacin; Lithium; Lithium Carbonate; Male; Middle Aged; Neurotoxicity Syndromes; Ofloxacin | 2000 |
[In vitro antimycobacterial activities of a new quinolone, balofloxacin].
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Mycobacterium; Ofloxacin | 2001 |
[In vitro antibacterial activity of prulifloxacin, a new oral quinolone, and comparative susceptibility rate at clinical breakpoint MIC].
Topics: Anti-Infective Agents; Bacteria; Dioxolanes; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Piperazines; Quinolones; Respiratory Tract Infections; Sepsis | 2000 |
Antimicrobial activity of fluoroquinolone photodegradation products determined by parallel-line bioassay and high performance liquid chromatography.
Topics: Anti-Infective Agents; Aza Compounds; Biological Assay; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacter cloacae; Escherichia coli; Fluoroquinolones; Klebsiella; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Photochemistry; Quinolines | 2001 |
Workplace costs associated with acute exacerbation of chronic bronchitis: a comparison of moxifloxacin and levofloxacin.
Topics: Absenteeism; Adolescent; Adult; Anti-Infective Agents; Bronchitis; Chronic Disease; Cost of Illness; Cost-Benefit Analysis; Efficiency; Employer Health Costs; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; United States | 2001 |
Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case-control study.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Case-Control Studies; Drug Resistance, Microbial; Female; Hong Kong; Humans; Levofloxacin; Lung Diseases, Obstructive; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumococcal Infections; Retrospective Studies; Risk Factors; Streptococcus pneumoniae | 2001 |
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture].
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins | 2000 |
Pharmacodynamics of moxifloxacin and levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis in an in vitro pharmacodynamic model.
Topics: Anti-Infective Agents; Aza Compounds; Fluoroquinolones; Humans; Levofloxacin; Models, Biological; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae | 2001 |
Urothelial mucosal concentration of levofloxacin administered before transurethral resection: Is the mucosal concentration predictable?
Topics: Aged; Anti-Infective Agents, Urinary; Female; Humans; Levofloxacin; Male; Middle Aged; Mucous Membrane; Ofloxacin; Preoperative Care; Tissue Distribution; Urethra; Urothelium | 2001 |
A whole blood bactericidal assay for tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin | 2001 |
Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa.
Topics: Animals; Anti-Infective Agents; Biological Transport, Active; Dipeptides; Drug Design; Drug Stability; Drug Synergism; Levofloxacin; Mice; Microbial Sensitivity Tests; Molecular Conformation; Molecular Structure; Ofloxacin; Pseudomonas aeruginosa; Rats; Structure-Activity Relationship | 2001 |
An HPLC assay and a microbiological assay to determine levofloxacin in soft tissue, bone, bile and serum.
Topics: Anti-Infective Agents; Bile; Biological Assay; Bone and Bones; Calibration; Chromatography, High Pressure Liquid; Humans; Levofloxacin; Ofloxacin; Quality Control | 2001 |
In vitro activity of four fluoroquinolones against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain | 2001 |
Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Microbial; Fever; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Ofloxacin; Streptococcaceae | 2001 |
Treatment of tularemia with levofloxacin.
Topics: Aged; Anti-Infective Agents; Francisella tularensis; Humans; Levofloxacin; Male; Ofloxacin; Tularemia | 2001 |
In vitro susceptibilities of bacterial ocular isolates to fluoroquinolones.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Conjunctivitis, Bacterial; Drug Evaluation; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2001 |
Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice.
Topics: Analgesics; Animals; Anti-Infective Agents; Antidepressive Agents; Anxiety; Hypnotics and Sedatives; Injections, Intraperitoneal; Levofloxacin; Male; Mice; Mice, Inbred BALB C; Motor Activity; Ofloxacin; Pentobarbital; Rats; Rats, Wistar; Reaction Time | 2001 |
Cerebrospinal fluid penetration and pharmacokinetics of levofloxacin in an experimental rabbit meningitis model.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Levofloxacin; Meningitis, Pneumococcal; Ofloxacin; Rabbits; Streptococcus pneumoniae | 2001 |
Tissue penetration of a single dose of levofloxacin intravenously for antibiotic prophylaxis in lung surgery.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Humans; Levofloxacin; Lung; Ofloxacin | 2001 |
Activity of oral agents against pediatric isolates of Streptococcus pneumoniae.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Child; Child, Preschool; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Lactams; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae | 2001 |
Activity of moxifloxacin and other quinolones against pneumococci resistant to first-line agents, or with high-level ciprofloxacin resistance.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae | 2001 |
Enantioseparation of ofloxacin in urine by capillary electrokinetic chromatography using charged cyclodextrins as chiral selectors and assessment of enantioconversion.
Topics: Chromatography; Cyclodextrins; Electrophoresis, Capillary; Humans; Levofloxacin; Ofloxacin | 2001 |
Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval.
Topics: Anti-Infective Agents, Urinary; Electrocardiography; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Syncope; Tachycardia, Ventricular; Urinary Tract Infections | 2001 |
Pharmacodynamics of moxifloxacin, levofloxacin and sparfloxacin against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Quinolines; Streptococcus pneumoniae; Time Factors | 2001 |
Pharmacokinetics of levofloxacin during continuous veno-venous hemofiltration.
Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Critical Illness; Female; Hemofiltration; Humans; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Statistics, Nonparametric | 2001 |
[Comparison of in vitro antimicrobial activities of ofloxacin, levofloxacin, ciprofloxacin, and sparfloxacin against various mycobacteria].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Mycobacterium; Mycobacterium fortuitum; Mycobacterium kansasii; Mycobacterium tuberculosis; Ofloxacin | 2001 |
Can antimicrobial susceptibility testing results for ciprofloxacin or levofloxacin predict susceptibility to a newer fluoroquinolone, gatifloxacin?: Report from The SENTRY Antimicrobial Surveillance Program (1997-99).
Topics: Anti-Infective Agents; Ciprofloxacin; Databases, Factual; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Pseudomonas aeruginosa | 2001 |
Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States.
Topics: Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Europe; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; United States | 2001 |
Comparison of antimycobacterial activity of grepafloxacin against Mycobacterium avium with that of levofloxacin: accumulation of grepafloxacin in human macrophages.
Topics: Anti-Infective Agents; Antitubercular Agents; Biological Transport; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Piperazines | 2001 |
gyrA mutations associated with quinolone resistance in Bacteroides fragilis group strains.
Topics: Amino Acid Substitution; Anti-Infective Agents; Aza Compounds; Bacteroides fragilis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines | 2001 |
Fluoroquinolone resistance in anaerobic bacteria following exposure to levofloxacin, trovafloxacin, and sparfloxacin in an in vitro pharmacodynamic model.
Topics: Anti-Infective Agents; Bacteroides; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Time Factors | 2001 |
Levofloxacin failure in a patient with pneumococcal pneumonia.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure | 2001 |
Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy.
Topics: Anti-Infective Agents; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Emphysema; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Theophylline | 2001 |
Safety of the new fluoroquinolones compared with ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines | 2000 |
Activity of levofloxacin and ciprofloxacin against urinary pathogens.
Topics: Anti-Infective Agents; Bacterial Adhesion; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Urinary Tract Infections | 2001 |
Levofloxacin-resistant Streptococcus pneumoniae: second look.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Streptococcus pneumoniae | 2001 |
Levofloxacin and warfarin interaction.
Topics: Aged; Anti-Infective Agents; Anticoagulants; Blood Coagulation; Drug Interactions; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Warfarin | 2001 |
Trends in ciprofloxacin nonsusceptibility and levofloxacin resistance among Streptococcus pneumoniae isolates in North America.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Population Surveillance; Streptococcus pneumoniae | 2001 |
Intravenous-to-oral transition therapy in community-acquired pneumonia: the INOVA Health System experience.
Topics: Administration, Oral; Aged; Anti-Infective Agents; APACHE; Ciprofloxacin; Community-Acquired Infections; Cost-Benefit Analysis; Drug Utilization; Female; Hospitalization; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Virginia | 2001 |
In vitro activity of levofloxacin against coagulase-positive and -negative staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Staphylococcus | 2001 |
In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Azithromycin; Body Weight; Fluoroquinolones; Gemifloxacin; Guinea Pigs; Half-Life; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Lung; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Survival Rate | 2001 |
Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; beta-Lactams; Enterobacteriaceae; Enterococcus faecalis; Fluoroquinolones; Indoles; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus; Vancomycin | 2001 |
Comparative in vitro bacteriostatic and bactericidal activity of trovafloxacin, levofloxacin and moxifloxacin against clinical and environmental isolates of Legionella spp.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Fluoroquinolones; Humans; Legionella; Legionellosis; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Rifampin | 2001 |
Transport of levofloxacin in the OK kidney epithelial cell line: interaction with p-aminohippurate transport.
Topics: Animals; Anti-Infective Agents; Biological Transport, Active; Cell Line; Epithelial Cells; Kidney; Kinetics; Levofloxacin; Ofloxacin; p-Aminohippuric Acid | 2001 |
Association of Mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis.
Topics: Adolescent; Adult; Anti-Infective Agents, Urinary; DNA Primers; DNA, Bacterial; Humans; Levofloxacin; Male; Middle Aged; Mycoplasma; Mycoplasma Infections; Ofloxacin; Polymerase Chain Reaction; Recurrence; Urethritis | 2001 |
Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Humans; Infusions, Parenteral; Levofloxacin; Methicillin; Nafcillin; Ofloxacin; Osteomyelitis; Penicillins; Rabbits; Staphylococcal Infections; Tibia | 2001 |
Differential response of mast cells separated from various organs and basophils of dogs to the fluoroquinolone antimicrobial levofloxacin.
Topics: Animals; Anti-Infective Agents; Basophils; Calcimycin; Connective Tissue; Dogs; Female; GTP-Binding Proteins; Histamine Release; Ionophores; L-Lactate Dehydrogenase; Levofloxacin; Liver; Male; Mast Cells; Mucous Membrane; Ofloxacin; Pertussis Toxin; Skin; Virulence Factors, Bordetella | 2001 |
In vitro activity of fluoroquinolones (gatifloxacin, levofloxacin and trovafloxacin) and seven other antibiotics against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2001 |
Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Point Mutation; Streptococcus pneumoniae | 2001 |
Pharmacokinetics of levofloxacin and ciprofloxacin during continuous renal replacement therapy in critically ill patients.
Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Critical Illness; Female; Hemofiltration; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Renal Insufficiency; Renal Replacement Therapy | 2001 |
Ciprofloxacin- and methicillin-resistant staphylococcus aureus susceptible to moxifloxacin, levofloxacin, teicoplanin, vancomycin and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Base Sequence; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Oxazolidinones; Polymerase Chain Reaction; Quinolines; Sensitivity and Specificity; Staphylococcus aureus; Teicoplanin; Vancomycin | 2001 |
Therapeutic effect of anti-TNF-alpha antibody and levofloxacin (LVFX) in a mouse model of enterohemorrhagic Escherichia coli O157 infection.
Topics: Animals; Anti-Infective Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Disease Models, Animal; Escherichia coli Infections; Escherichia coli O157; Female; Germ-Free Life; Immunoglobulin G; Kidney; Levofloxacin; Male; Mice; Ofloxacin; Shiga Toxin; Survival Analysis; Time Factors; Tumor Necrosis Factor-alpha | 2001 |
Comparison of therapeutic interchange with standard educational tools for influencing fluoroquinolone prescribing.
Topics: Anti-Infective Agents; Chi-Square Distribution; Ciprofloxacin; Cost Control; Cost Savings; Drug Costs; Drug Utilization; Female; Hospital Bed Capacity; Humans; Levofloxacin; Male; Ofloxacin; Pharmacy Service, Hospital; Practice Patterns, Physicians'; Statistics, Nonparametric; Therapeutic Equivalency; Treatment Outcome; Virginia | 2001 |
Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis.
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Meningitis, Escherichia coli; Meningitis, Meningococcal; Meningitis, Pneumococcal; Middle Aged; Ofloxacin | 2001 |
Acute fatal hepatitis related to levofloxacin.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chemical and Drug Induced Liver Injury; Fatal Outcome; Humans; Levofloxacin; Liver Failure, Acute; Male; Ofloxacin; Urinary Tract Infections | 2001 |
An in vitro resistance study of levofloxacin, ciprofloxacin, and ofloxacin using keratitis isolates of Staphylococcus aureus and Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Microbial; Eye Infections, Bacterial; Humans; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus aureus; Time Factors | 2001 |
Activity of linezolid against levofloxacin-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in Hong Kong.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacterial Infections; Hong Kong; Humans; Levofloxacin; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Staphylococcus aureus; Streptococcus pneumoniae; Vancomycin Resistance | 2001 |
Levofloxacin-warfarin interaction.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Anticoagulants; Drug Interactions; Female; Follow-Up Studies; Hemorrhage; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Warfarin | 2001 |
Emergence of extremely high penicillin and cefotaxime resistance and high-level levofloxacin resistance in clinical isolates of Streptococcus pneumoniae in Hungary.
Topics: Anti-Infective Agents; Cefotaxime; Cephalosporins; Drug Resistance, Bacterial; Humans; Hungary; Levofloxacin; Ofloxacin; Penicillin Resistance; Penicillins; Streptococcus pneumoniae | 2001 |
Clinical isolates of Streptococcus pneumoniae resistant to levofloxacin contain mutations in both gyrA and parC genes.
Topics: Amino Acid Substitution; Anti-Infective Agents; Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Point Mutation; Streptococcus pneumoniae | 2001 |
Multicentre study of the in vitro evaluation of moxifloxacin and other quinolones against community acquired respiratory pathogens.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Community-Acquired Infections; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Respiratory Tract Infections; Streptococcus pneumoniae; Streptococcus pyogenes | 2001 |
[Achilles pain and functional impotence in a patient with chronic obstructive pulmonary disease with pneumonia. Tendon rupture caused by levofloxacin].
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Humans; Levofloxacin; Male; Ofloxacin; Pain; Pneumonia; Pulmonary Disease, Chronic Obstructive; Rupture | 2001 |
[Comparative study of the bacteriostatic and bactericidal activity of levofloxacin against Pasteurella strains isolated from man].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pasteurella | 2001 |
Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease.
Topics: Acute Disease; Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Infusions, Intravenous; Levofloxacin; Liver; Liver Diseases; Liver Function Tests; Ofloxacin; Pulmonary Disease, Chronic Obstructive | 2001 |
Rapid method for detection of gyrA and grlA mutations in unrelated strains of Staphylococci susceptible and resistant to levofloxacin.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Genetic Testing; Genotype; Levofloxacin; Methicillin Resistance; Mutation; Ofloxacin; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Staphylococcus aureus | 2001 |
Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2.
Topics: Adenosine Triphosphate; Anti-Infective Agents; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Chlorides; Cyclosporine; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Levofloxacin; Ofloxacin; Piperazines | 2001 |
Accumulation of five fluoroquinolones by Mycobacterium tuberculosis H37Rv.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolines | 2001 |
Spectrum and activity of three contemporary fluoroquinolones tested against Pseudomonas aeruginosa isolates from urinary tract infections in the SENTRY Antimicrobial Surveillance Program (Europe and the Americas; 2000): more alike than different!
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Resistance, Bacterial; Europe; Fluoroquinolones; Gatifloxacin; Humans; Lactams; Latin America; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Population Surveillance; Pseudomonas aeruginosa; Pseudomonas Infections; Regional Medical Programs; Urinary Tract Infections | 2001 |
Prevalence of single mutations in topoisomerase type II genes among levofloxacin-susceptible clinical strains of Streptococcus pneumoniae isolated in the United States in 1992 to 1996 and 1999 to 2000.
Topics: Anti-Infective Agents; DNA Topoisomerases, Type II; Gene Frequency; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Point Mutation; Streptococcus pneumoniae; United States | 2002 |
Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations.
Topics: Anti-Infective Agents; Aza Compounds; DNA Topoisomerases, Type I; Fluoroquinolones; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Quinolones; Staphylococcus aureus | 2002 |
Pharmacodynamics of trovafloxacin and levofloxacin against Bacteroides fragilis in an in vitro pharmacodynamic model.
Topics: Anti-Infective Agents; Area Under Curve; Bacteroides fragilis; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Time Factors | 2002 |
Therapeutic efficacy of intraperitoneal polymyxin B and polymyxin-like peptides alone or combined with levofloxacin in rat models of septic shock.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Levofloxacin; Male; Ofloxacin; Polymyxin B; Rats; Rats, Wistar; Shock, Septic | 2002 |
Pharmacodynamic profiling of levofloxacin and gatifloxacin using Monte Carlo simulation for community-acquired isolates of Streptococcus pneumoniae.
Topics: Adolescent; Adult; Anti-Infective Agents; Area Under Curve; Community-Acquired Infections; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Models, Statistical; Monte Carlo Method; Ofloxacin; Predictive Value of Tests; Streptococcus pneumoniae | 2001 |
Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Electrocardiography; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies; Torsades de Pointes | 2001 |
[Efficacy of a single-day administration of levofloxacin for the prevention of urinary tract infections after urogenital examinations and treatments for outpatients].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents, Urinary; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Outpatients; Urinary Tract Infections | 2001 |
Clinical effects and bronchoalveolar transfer of levofloxacin in patients with community-acquired pneumonia.
Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Bronchoalveolar Lavage Fluid; Community-Acquired Infections; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Time Factors; Treatment Outcome | 2001 |
Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Europe; Fluoroquinolones; Gemifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin | 2001 |
Resistance of Streptococcus pneumoniae to fluoroquinolones--United States, 1995-1999.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States | 2001 |
Susceptibilities to telithromycin and six other agents and prevalence of macrolide resistance due to L4 ribosomal protein mutation among 992 Pneumococci from 10 central and Eastern European countries.
Topics: Age Factors; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Bacterial; Europe; Gene Frequency; Humans; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Ribosomal Proteins; Serotyping; Streptococcus pneumoniae | 2002 |
Effect of prolonged treatment with azithromycin, clarithromycin, or levofloxacin on Chlamydia pneumoniae in a continuous-infection Model.
Topics: Anti-Bacterial Agents; Azithromycin; Chlamydophila pneumoniae; Clarithromycin; Cytokines; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Tumor Cells, Cultured | 2002 |
Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Rifamycins | 2002 |
Selection of Streptococcus pneumoniae mutants having reduced susceptibility to moxifloxacin and levofloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2002 |
Pharmacokinetics of antituberculosis medications delivered via percutaneous gastrojejunostomy tube.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Female; Gastrostomy; Humans; Jejunostomy; Levofloxacin; Ofloxacin; Rifampin; Saskatchewan; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2002 |
In vitro susceptibility testing of levofloxacin and ofloxacin by microtiter plate Alamar blue against multidrug and non multidrug resistant Mycobacterium tuberculosis in Thailand.
Topics: Coloring Agents; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Sensitivity and Specificity; Tuberculosis, Multidrug-Resistant; Xanthenes | 2001 |
Effect of subminimal inhibitory concentrations of three fluoroquinolones on adherence of uropathogenic strains of Escherichia coli.
Topics: Anti-Infective Agents; Bacterial Adhesion; Cell Line; Ciprofloxacin; Escherichia coli; Escherichia coli Infections; Female; Hemagglutination; Humans; Inhibitory Concentration 50; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Urinary Tract Infections | 2002 |
In vitro synergy testing of levofloxacin, ofloxacin, and ciprofloxacin in combination with aztreonam, ceftazidime, or piperacillin against Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Aztreonam; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Synergism; Humans; Lactams; Levofloxacin; Microbial Sensitivity Tests; Monobactams; Ofloxacin; Penicillins; Piperacillin; Pseudomonas aeruginosa | 2002 |
Determining the frequency of resistance of Streptococcus pneumoniae to ciprofloxacin, levofloxacin, trovafloxacin, grepafloxacin, and gemifloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Streptococcus pneumoniae | 2001 |
Comparison of Etest, agar dilution, broth microdilution and disk diffusion methods for testing in vitro activity of levofloxacin against Staphylococcus spp. isolated from neutropenic cancer patients.
Topics: Agar; Anti-Infective Agents; Culture Media; Diffusion; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Neoplasms; Neutropenia; Ofloxacin; Staphylococcus | 2002 |
[Adverse drug reaction and rational use of levofloxacin: a prospective study].
Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Anti-Infective Agents; Bacterial Infections; Drug Combinations; Female; Humans; Levofloxacin; Male; Middle Aged; Multicenter Studies as Topic; Ofloxacin | 2001 |
[Acute pancreatitis after treatment by levofloxacin and methylprednisolone].
Topics: Acute Disease; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Female; Humans; Levofloxacin; Methylprednisolone; Ofloxacin; Pancreatitis | 2001 |
Lung tissue distribution after intravenous administration of grepafloxacin: comparative study with levofloxacin.
Topics: Animals; Anti-Infective Agents; Epithelium; Fluoroquinolones; Infusions, Intravenous; Levofloxacin; Lung; Lymph; Molecular Structure; Ofloxacin; Piperazines; Pulmonary Circulation; Sheep; Time Factors | 2002 |
[In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin].
Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Drug Resistance; Drug Resistance, Multiple, Bacterial; Erythromycin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Penicillins; Quinolines; Streptococcal Infections; Streptococcus | 2001 |
Peptidomimetics of efflux pump inhibitors potentiate the activity of levofloxacin in Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Biological Transport, Active; Drug Synergism; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Mimicry; Molecular Structure; Ofloxacin; Peptide Fragments; Pseudomonas aeruginosa; Structure-Activity Relationship | 2002 |
Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Availability; Cyclosporine; Enzyme Inhibitors; Fluoroquinolones; Genes, MDR; Intestinal Mucosa; Kidney; Levofloxacin; Liver; Male; Mice; Mice, Knockout; Ofloxacin; Piperazines; Rats; Tissue Distribution | 2002 |
In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.
Topics: Animals; Anti-Infective Agents; Clindamycin; Colony Count, Microbial; DNA Topoisomerase IV; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Gene Frequency; Genes, Bacterial; Gentamicins; Levofloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mutation; Ofloxacin; Quinolines; Quinolizines; Staphylococcal Skin Infections; Staphylococcus aureus; Staphylococcus epidermidis; Topoisomerase II Inhibitors | 2002 |
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Limb Buds; Magnesium; Male; Mice; Mice, Inbred Strains; Ofloxacin; Piperazines; Pregnancy; Quinolones | 2002 |
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Drug Resistance, Bacterial; Fatal Outcome; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure | 2002 |
Clostridium difficile infection associated with levofloxacin treatment.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Feces; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Risk Factors | 2002 |
Levofloxacin treatment failure in a patient with fluoroquinolone-resistant Streptococcus pneumoniae pneumonia.
Topics: Anti-Infective Agents; Colony Count, Microbial; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance; Drug Resistance, Microbial; Humans; Levofloxacin; Male; Middle Aged; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure | 2002 |
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Sensitivity and Specificity; Staphylococcus aureus | 2002 |
[Mycobacterium abscessus infection complicated with diabetes mellitus].
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Diabetes Complications; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Ofloxacin; Tuberculosis, Pulmonary | 2002 |
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Cefazolin; Cefotaxime; Cephalosporins; Clindamycin; Corynebacterium; Drug Resistance, Bacterial; Erythromycin; Eubacterium; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Imipenem; Levofloxacin; Ofloxacin; Penicillins; Peptostreptococcus; Periodontitis; Staphylococcus; Streptococcus; Sulbactam; Thienamycins; Tooth Diseases | 2002 |
Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies | 2002 |
In vitro and in vivo activities of ciprofloxacin and levofloxacin against an SHV-5 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae strain.
Topics: Animals; Anti-Infective Agents; beta-Lactamases; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin | 2002 |
Fluoroquinolone concentrations in plasma, urine, and bile after oral administration in rats with renal failure: useful technique for long-term bile collection.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bile; Blood Urea Nitrogen; Fluoroquinolones; Levofloxacin; Male; Ofloxacin; Osmolar Concentration; Piperazines; Rats; Rats, Wistar; Reference Values; Renal Insufficiency; Specimen Handling | 2001 |
Comparison of levofloxacin, alatrofloxacin, and vancomycin for prophylaxis and treatment of experimental foreign-body-associated infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Disease Models, Animal; Fluoroquinolones; Foreign-Body Reaction; Guinea Pigs; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Rats; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2002 |
Shiga-like toxin II derived from Escherichia coli O157:H7 modifies renal handling of levofloxacin in rats.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carrier Proteins; Escherichia coli O157; Glomerular Filtration Rate; Humans; Kidney; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Rats; Rats, Wistar; Shiga Toxin 2 | 2002 |
[Antibiotic ophthalmic solutions evaluated by pharmacokinetic parameters of maximum concentration in the aqueous].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Aqueous Humor; Cefmenoxime; Chloramphenicol; Erythromycin; Gentamicins; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Rabbits; Sulbenicillin | 2002 |
Levaquin induced acute tubulointerstitial nephritis--two case reports.
Topics: Adult; Anti-Infective Agents; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Levofloxacin; Nephritis, Interstitial; Ofloxacin | 2002 |
Elimination of levofloxacin in critically ill patients with renal failure: influence of continuous veno-venous hemofiltration.
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Critical Illness; Female; Hemofiltration; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin; Renal Insufficiency | 2002 |
Investigation into the selection frequency of resistant mutants and the bacterial kill rate by levofloxacin and ciprofloxacin in non-mucoid Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Selection, Genetic; Time Factors | 2002 |
Bacteremia due to viridans group Streptococci with diminished susceptibility to Levofloxacin among neutropenic patients receiving levofloxacin prophylaxis.
Topics: Adult; Aged; Anti-Infective Agents; Bacteremia; Chemoprevention; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Ofloxacin; Streptococcus | 2002 |
Separation of levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, trovafloxacin and cinoxacin by high-performance liquid chromatography: application to levofloxacin determination in human plasma.
Topics: Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Levofloxacin; Ofloxacin; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2002 |
[Determination of levofloxacin in plasma and cerebrospinal fluid with HPLC and its pharmacokinetics in patients undergoing neurosurgical operations].
Topics: Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Female; Humans; Levofloxacin; Male; Middle Aged; Neurosurgical Procedures; Ofloxacin | 1998 |
Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV of Enterococcus faecalis.
Topics: Anti-Infective Agents; Cloning, Molecular; DNA Gyrase; DNA Topoisomerase IV; Enterococcus faecalis; Genetic Vectors; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Ofloxacin; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase II Inhibitors | 2002 |
Risk factors associated with nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection including previous use of antimicrobials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chi-Square Distribution; Confidence Intervals; Cross Infection; Female; Humans; Length of Stay; Levofloxacin; Logistic Models; Macrolides; Male; Methicillin Resistance; Middle Aged; Odds Ratio; Ofloxacin; Retrospective Studies; Risk Factors; Staphylococcal Infections; Staphylococcus aureus | 2002 |
In vitro activity of levofloxacin against contemporary clinical isolates of Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae from North America and Europe.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chlamydophila pneumoniae; Doxycycline; Drug Resistance, Bacterial; Europe; Humans; Legionella pneumophila; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Mycoplasma pneumoniae; North America; Ofloxacin | 2002 |
[Levofloxacin and acute confusional syndrome].
Topics: Acute Disease; Adult; Anti-Infective Agents; Confusion; Humans; Levofloxacin; Male; Ofloxacin | 2002 |
Limited tolerability of levofloxacin and pyrazinamide for multidrug-resistant tuberculosis prophylaxis in a solid organ transplant population.
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Organ Transplantation; Pyrazinamide; Retrospective Studies; Transplantation Immunology; Tuberculosis | 2002 |
Levofloxacin-induced toxic epidermal necrolysis in an elderly patient.
Topics: Aged; Anti-Infective Agents; Community-Acquired Infections; Female; Fluid Therapy; Humans; Levofloxacin; Ofloxacin; Pneumonia; Pulmonary Disease, Chronic Obstructive; Skin; Stevens-Johnson Syndrome | 2002 |
[Changes of antibody titers during antimicrobial therapy including levofloxacin for Chlamydia infections in the obstetrics and gynecology field].
Topics: Antibodies, Bacterial; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Clarithromycin; Drug Therapy, Combination; Female; Humans; Immunoglobulin G; Levofloxacin; Maternal-Fetal Exchange; Ofloxacin; Pregnancy; Pregnancy Complications, Infectious | 2002 |
[Vascular graft infection by Staphylococcus epidermidis: efficacy of various perioperative prophylaxis protocols in an animal model].
Topics: Animals; Blood Vessel Prosthesis Implantation; Cefazolin; Drug Evaluation, Preclinical; Drug Implants; Drug Resistance; Drug Therapy, Combination; Injections, Intraperitoneal; Levofloxacin; Male; Methicillin Resistance; Models, Animal; Ofloxacin; Oxacillin; Premedication; Prostheses and Implants; Prosthesis-Related Infections; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis; Teicoplanin | 2001 |
Single- and multistep selection study of the antipneumococcal activity of BMS-284756 compared to ciprofloxacin, levofloxacin, trovafloxacin and moxifloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2002 |
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
Topics: Aged; Anti-Infective Agents; Bacteremia; Drug Resistance, Bacterial; Fatal Outcome; Humans; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure | 2002 |
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2002 |
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2002 |
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
Topics: Anti-Infective Agents; Canada; Drug Resistance, Bacterial; Drug Utilization; Hospitals; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae | 2002 |
Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ceftriaxone; Child; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; United States | 2002 |
Rhodococcus equi: pulmonary cavitation lesion in patient infected with HIV cured by levofloxacin and rifampicin.
Topics: Actinomycetales Infections; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; HIV Infections; Humans; Levofloxacin; Lung Diseases; Male; Ofloxacin; Rhodococcus equi; Rifampin | 2002 |
Comparative in vitro activity of levofloxacin and ciprofloxacin against bacterial isolates from neutropenic patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Staphylococcus aureus; Stenotrophomonas maltophilia | 2002 |
[Update on the use of levofloxacin in the management of acute exacerbations of chronic bronchitis with risk factors].
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chronic Disease; Drug Resistance; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Patient Care Planning; Recurrence; Risk Factors | 2002 |
[Update on the role of levofloxacin in the management of acute community-acquired pneumonia].
Topics: Acute Disease; Anti-Infective Agents; Bacteremia; Community-Acquired Infections; Humans; Levofloxacin; Ofloxacin; Pneumonia; Randomized Controlled Trials as Topic; Treatment Outcome | 2002 |
Adverse events associated with pyrazinamide and levofloxacin in the treatment of latent multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Anti-Infective Agents; Antitubercular Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyrazinamide; Tuberculosis, Multidrug-Resistant | 2002 |
Clinical use of Levofloxacin in the long-term treatment of drug resistant tuberculosis.
Topics: Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Tuberculosis, Female Genital; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2002 |
Levofloxacin alone efficiently treated a cutaneous mycobacterium fortuitum infection.
Topics: Administration, Oral; Adolescent; Anti-Infective Agents; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Skin Diseases, Bacterial; Treatment Outcome | 2002 |
Pharmacokinetic study of levofloxacin in rat blood and bile by microdialysis and high-performance liquid chromatography.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Levofloxacin; Male; Microdialysis; Ofloxacin; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2002 |
Nephrotoxicity and purpura associated with levofloxacin.
Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Diuretics; Drug Eruptions; Furosemide; Humans; Kidney Function Tests; Levofloxacin; Liver Function Tests; Lung Neoplasms; Male; Myeloproliferative Disorders; Ofloxacin; Prednisone; Purpura | 2002 |
[Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].
Topics: Adult; Aged; Ampicillin; Anti-Infective Agents; beta-Lactamases; Cefaclor; Cephalosporins; Child, Preschool; Female; Haemophilus influenzae; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Respiratory System; Seasons; Sulbactam; Thienamycins | 2002 |
Side effects of levofloxacin.
Topics: Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin; Safety; Tendinopathy | 2002 |
Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Genotype; Humans; Levofloxacin; Lung; Male; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Pulmonary Edema; Rabbits; Spleen; Streptococcus pneumoniae | 2002 |
Quinupristin/dalfopristin bonding in combination with intraperitoneal antibiotics prevent infection of knitted polyester graft material in a subcutaneous rat pouch model infected with resistant Staphylococcus epidermidis.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Disease Models, Animal; Doxycycline; Drug Therapy, Combination; Injections, Intraperitoneal; Levofloxacin; Male; Ofloxacin; Polyesters; Prosthesis-Related Infections; Rats; Staphylococcal Infections; Staphylococcus epidermidis; Virginiamycin | 2002 |
Pulse polarographic determination of levofloxacin in tablets.
Topics: Anti-Infective Agents; Calibration; Hydrogen-Ion Concentration; Levofloxacin; Ofloxacin; Polarography; Spectrophotometry, Ultraviolet; Tablets | 2002 |
[Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS].
Topics: Abscess; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Immunocompromised Host; Levofloxacin; Male; Middle Aged; Mycobacterium haemophilum; Mycobacterium Infections; Ofloxacin; Osteomyelitis; Recurrence; Rifabutin; Tibia | 2002 |
Levofloxacin and warfarin interaction.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Drug Administration Schedule; Drug Synergism; Female; Humans; International Normalized Ratio; Levofloxacin; Male; Middle Aged; Ofloxacin; Prothrombin Time; Warfarin | 2002 |
In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.
Topics: Animals; Anti-Infective Agents; Chromosome Aberrations; Dose-Response Relationship, Drug; Fluoroquinolones; Levofloxacin; Light; Male; Mice; Mice, Hairless; Micronuclei, Chromosome-Defective; Micronucleus Tests; Ofloxacin; Photosensitizing Agents; Quinolones; Skin; Time Factors | 2002 |
Single and multi-step resistance selection study in Streptococcus pneumoniae comparing ceftriaxone with levofloxacin, gatifloxacin and moxifloxacin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ceftriaxone; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Selection, Genetic; Streptococcus pneumoniae | 2002 |
Phenotypic and genotypic analysis of levofloxacin-resistant clinical isolates of Streptococcus pneumoniae collected in 13 countries during 1999-2000.
Topics: Anti-Infective Agents; Asia; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Europe; Genotype; Humans; Levofloxacin; Mexico; Microbial Sensitivity Tests; Mutation; Ofloxacin; Phenotype; Pneumococcal Infections; Sequence Analysis, DNA; South Africa; Streptococcus pneumoniae | 2002 |
A study on the toxicity of intravitreal levofloxacin in rabbits.
Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Injections; Levofloxacin; Ofloxacin; Rabbits; Retina; Vitreous Body | 2002 |
The effect of levofloxacin concentration on the development and maintenance of antibiotic-resistant clones of Escherichia coli in chemostat culture.
Topics: Anti-Infective Agents; Bacterial Proteins; Culture Media; Drug Resistance, Multiple, Bacterial; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Selection, Genetic | 2002 |
AUC/MIC relationships to different endpoints of the antimicrobial effect: multiple-dose in vitro simulations with moxifloxacin and levofloxacin.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Endpoint Determination; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2002 |
The determination of levofloxacin by flow injection analysis using UV detection, potentiometry, and conductometry in pharmaceutical preparations.
Topics: Conductometry; Flow Injection Analysis; Levofloxacin; Ofloxacin; Pharmaceutical Preparations; Potentiometry; Spectrophotometry, Ultraviolet | 2002 |
Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.
Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sensitivity and Specificity; Tazobactam | 2002 |
Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae.
Topics: Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Sensitivity and Specificity; Streptococcus pneumoniae | 2002 |
Tear concentrations of levofloxacin following topical administration of a single dose of 0.5% levofloxacin ophthalmic solution in healthy volunteers.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Infective Agents; Biological Availability; Chromatography, High Pressure Liquid; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Reagent Strips; Tears; Time Factors | 2002 |
Comparative in vitro activity of penicillin G, levofloxacin, moxifloxacin, telithromycin, pristinamycin, quinupristin-dalfopristin and linezolid against ofloxacin-intermediate and -resistant Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Ketolides; Lactams; Levofloxacin; Linezolid; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Oxazolidinones; Penicillin G; Pristinamycin; Quinolines; Streptococcus pneumoniae; Virginiamycin | 2002 |
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2002 |
[Sensitivity of Mycobacterium tuberculosis to levofloxacin].
Topics: Anti-Infective Agents; Bacteriological Techniques; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin | 2002 |
[Sensitivity to levofloxacin of Mycobacterium tuberculosis strains with various phenotype isolated from patients with newly diagnosed and chronic tuberculosis].
Topics: Anti-Infective Agents; Chronic Disease; Drug Resistance, Bacterial; Genotype; Humans; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Pulmonary | 2002 |
[Sensitivity to levofloxacin of various types of non-tuberculosis Mycobacterium].
Topics: Dose-Response Relationship, Drug; Levofloxacin; Mycobacterium; Ofloxacin; Russia | 2002 |
The comparison of in the vitro effect of imipenem or meropenem combined with ciprofloxacin or levofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2002 |
Aqueous humor levels of topically applied levofloxacin in human eyes.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Infective Agents; Aqueous Humor; Female; Humans; Immunologic Techniques; Levofloxacin; Male; Middle Aged; Ofloxacin; Osmolar Concentration | 2002 |
[The use of levofloxacin for the empirical treatment of exacerbations of mild, chronic COPD: Is it justified in under-65-years-old patients with no comorbidity?].
Topics: Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Infections | 2002 |
Physical therapist management of fluoroquinolone-induced Achilles tendinopathy.
Topics: Achilles Tendon; Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Maxillary Sinusitis; Ofloxacin; Orthotic Devices; Physical Therapy Modalities; Rupture; Treatment Outcome | 2002 |
[Gene sequencing analysis of DNA gyrase and topoisomerase IV as levofloxacin resistance in Streptococcus pneumoniae].
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Levofloxacin; Ofloxacin; Streptococcus pneumoniae | 2002 |
Pharmacoeconomics of a pharmacist-managed program for automatically converting levofloxacin route from i.v. to oral.
Topics: Administration, Oral; Anti-Infective Agents; Chi-Square Distribution; Cost Control; Economics, Pharmaceutical; Humans; Injections, Intravenous; Length of Stay; Levofloxacin; Ofloxacin; Pharmacists; Prospective Studies; Statistics, Nonparametric | 2002 |
Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Sensitivity and Specificity | 2002 |
In vitro activity of moxifloxacin, levofloxacin, gatifloxacin and linezolid against Mycobacterium tuberculosis.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Quinolines; Tuberculosis | 2002 |
Bactericidal activity of levofloxacin, gatifloxacin, penicillin, meropenem and rokitamycin against Bacillus anthracis clinical isolates.
Topics: Anthrax; Anti-Bacterial Agents; Anti-Infective Agents; Bacillus anthracis; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Miocamycin; Ofloxacin; Penicillins; Thienamycins | 2002 |
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2002 |
Moxifloxacin: new preparation. A me-too with more cardiac risks.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Approval; Fluoroquinolones; France; Humans; Levofloxacin; Long QT Syndrome; Ofloxacin; Pneumonia | 2002 |
The activity of levofloxacin and comparator agents against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999 and 2000.
Topics: Africa; Americas; Anti-Bacterial Agents; Asia; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Europe; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae; Vancomycin | 2002 |
In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Haemophilus influenzae; Korea; Levofloxacin; Microbial Sensitivity Tests; Moraxella; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2002 |
Microbiologic effectiveness of time- or concentration-based dosing strategies in Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Area Under Curve; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Streptococcus pneumoniae; Time Factors | 2002 |
Pharmacokinetic aspects of levofloxacin 500 mg once daily during sequential intravenous/oral therapy in patients with lower respiratory tract infections.
Topics: Administration, Oral; Aged; Aged, 80 and over; Area Under Curve; Cohort Studies; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Respiratory Tract Infections; Statistics, Nonparametric | 2003 |
Worldwide antimicrobial susceptibility patterns and pharmacodynamic comparisons of gatifloxacin and levofloxacin against Streptococcus pneumoniae: report from the Antimicrobial Resistance Rate Epidemiology Study Team.
Topics: Anti-Infective Agents; Area Under Curve; Drug Resistance, Bacterial; Epidemiologic Methods; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 2003 |
Infective endocarditis due to Haemophilus aphrophilus treated with levofloxacin.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography, Transesophageal; Endocarditis, Bacterial; Follow-Up Studies; Haemophilus; Haemophilus Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Risk Assessment; Treatment Outcome | 2002 |
[Tenotoxic potential of fluoroquinolones in the choice of surgical antibiotic prophylaxis in ophthalmology].
Topics: Achilles Tendon; Aged; Animals; Antibiotic Prophylaxis; Cells, Cultured; Ciprofloxacin; Data Interpretation, Statistical; Fluoroquinolones; Free Radicals; Humans; Levofloxacin; Middle Aged; Ofloxacin; Ophthalmologic Surgical Procedures; Pefloxacin; Rabbits; Rupture; Tendons; Time Factors | 2002 |
[Multisystemic severe infection with Chlamydia pneumoniae].
Topics: Adult; Anti-Infective Agents; Capillary Leak Syndrome; Chlamydia Infections; Chlamydophila pneumoniae; Humans; Levofloxacin; Male; Ofloxacin; Skin; Treatment Outcome; Vasculitis | 2002 |
[Rupture of the Achilles' tendon secondary to levofloxacin].
Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans; Intestinal Perforation; Levofloxacin; Male; Methylprednisolone; Metronidazole; Ofloxacin; Rupture; Tendinopathy | 2003 |
Fluoroquinolone resistance in Streptococcus pyogenes.
Topics: Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes | 2003 |
Distinct transport activity of tetraethylammonium from L-carnitine in rat renal brush-border membranes.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport, Active; Carnitine; Hydrogen-Ion Concentration; Kidney; Levofloxacin; Male; Microvilli; Ofloxacin; Organic Cation Transport Proteins; Rats; Rats, Wistar; Sulfhydryl Reagents; Tetraethylammonium | 2003 |
Levofloxacin and ciprofloxacin in vitro activities against 4,003 clinical bacterial isolates collected in 24 Italian laboratories.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2003 |
Levofloxacin-induced granulomatous interstitial nephritis.
Topics: Female; Granuloma; Humans; Levofloxacin; Middle Aged; Nephritis, Interstitial; Ofloxacin; Urinary Tract Infections | 2003 |
[Levofloxacin and bilateral spontaneous Achilles tendon rupture].
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Confusion; Humans; Levofloxacin; Male; Ofloxacin; Rupture, Spontaneous | 2003 |
[Achilles tendinitis associated to levofloxacin: report of 4 cases].
Topics: Achilles Tendon; Adult; Aged; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tendinopathy | 2002 |
Inhibition by fluoroquinolones of K(+) currents in rat dissociated hippocampal neurons.
Topics: Animals; Dose-Response Relationship, Drug; Fleroxacin; Fluoroquinolones; Hippocampus; Levofloxacin; Membrane Potentials; Neurons; Ofloxacin; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley | 2003 |
Tendon abnormalities and hypersensitivity of levofloxacin.
Topics: Anti-Infective Agents; Humans; Hypersensitivity; Levofloxacin; Ofloxacin; Rupture; Tendons | 2003 |
Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model.
Topics: Anti-Infective Agents; Area Under Curve; Colony Count, Microbial; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Half-Life; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Mutation; Naphthyridines; Ofloxacin; Streptococcus pneumoniae | 2003 |
In vitro activities of rifamycin derivatives ABI-1648 (Rifalazil, KRM-1648), ABI-1657, and ABI-1131 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rifamycins | 2003 |
Spontaneous Achilles tendon rupture in patients treated with levofloxacin.
Topics: Achilles Tendon; Aged; Female; Humans; Levofloxacin; Male; Ofloxacin; Rupture, Spontaneous | 2003 |
[Comparative in vitro activities of several antimicrobial agents against Helicobacter pylori].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Gastric Mucosa; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Stomach Ulcer | 2002 |
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones | 2002 |
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Time Factors | 2002 |
[Antibacterial activity of gatifloxacin against various fresh clinical isolates in 2002].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cefdinir; Cephalosporins; Ciprofloxacin; Dosage Forms; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Macrolides; Ofloxacin; Otorhinolaryngologic Diseases; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors; Urinary Tract Infections | 2002 |
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Topoisomerase II Inhibitors | 2002 |
Ultrasonography of non-traumatic rupture of the Achilles tendon secondary to levofloxacin.
Topics: Achilles Tendon; Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Muscular Diseases; Ofloxacin; Rupture, Spontaneous; Ultrasonography | 2003 |
Effect of levofloxacin coadministration on the international normalized ratios during warfarin therapy.
Topics: Aged; Aged, 80 and over; Drug Interactions; Drug Therapy, Combination; Female; Hospitals, Veterans; Humans; International Normalized Ratio; Levofloxacin; Male; Middle Aged; Ofloxacin; Warfarin | 2003 |
AUC(0-t)/MIC is a continuous index of fluoroquinolone exposure and predictive of antibacterial response for Streptococcus pneumoniae in an in vitro infection model.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Culture Media; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Predictive Value of Tests; Quinolines; Streptococcus pneumoniae | 2003 |
Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient.
Topics: Acute Disease; Aged; Anti-Infective Agents; Cellulitis; Chemical and Drug Induced Liver Injury; Humans; Kidney Failure, Chronic; Levofloxacin; Male; Ofloxacin; Renal Dialysis | 2003 |
Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters.
Topics: Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Time Factors | 2002 |
Antibiotic therapy for ambulatory patients with community-acquired pneumonia in an emergency department setting.
Topics: Adolescent; Adult; Aged; Alberta; Ambulatory Care; Analysis of Variance; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Community-Acquired Infections; Emergency Service, Hospital; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2003 |
Reply to: Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Disease Models, Animal; Levofloxacin; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Rabbits; Streptococcus pneumoniae | 2003 |
[Comparative in vitro bacteriostatic and bactericidal activity of levofloxacin and ciprofloxacin against urinary tract pathogens determined by MIC, MBC, Time-Kill curves and bactericidal index analysis].
Topics: Anti-Infective Agents; Ciprofloxacin; Gram-Negative Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Urinary Tract Infections | 2002 |
Levofloxacin kills Chlamydia pneumoniae and modulates interleukin 6 production by HEp-2 cells.
Topics: Anti-Infective Agents; Carcinoma; Chlamydia Infections; Chlamydophila pneumoniae; Hepatocytes; Humans; Interleukin-6; Levofloxacin; Liver Neoplasms; Ofloxacin; Tumor Cells, Cultured | 2003 |
Comparison of the bactericidal activity of moxifloxacin and levofloxacin against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Aza Compounds; Colony-Forming Units Assay; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Serum Bactericidal Test; Species Specificity; Staphylococcus aureus; Staphylococcus epidermidis | 2003 |
Emergence of phenotypic resistance to ciprofloxacin and levofloxacin in methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains.
Topics: Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Phenotype; Serial Passage; Staphylococcus aureus | 2003 |
Treatment with rokitamycin suppresses the lethality in a murine model of Escherichia coli O157:H7 infection.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Colony Count, Microbial; Disease Models, Animal; Escherichia coli Infections; Escherichia coli O157; Feces; Levofloxacin; Male; Mice; Mice, Inbred C3H; Miocamycin; Ofloxacin; Survival Analysis | 2003 |
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide | 2002 |
[Susceptibility of Streptococcus pyogenes to macrolides and quinolones in Guadalajara, Spain].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Levofloxacin; Ofloxacin; Penicillins; Retrospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes | 2003 |
Reoccurrence of levofloxacin-induced tendinitis by phenoxymethylpenicillin therapy after 6 months: a rare complication of fluoroquinolone therapy?
Topics: Achilles Tendon; Adverse Drug Reaction Reporting Systems; Aged; Anti-Bacterial Agents; Arthritis; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Penicillin V; Recurrence; Tendinopathy | 2003 |
Levofloxacin elimination during albumin dialysis.
Topics: Adult; Albumins; Anti-Infective Agents; Crigler-Najjar Syndrome; Dialysis; Female; Humans; Levofloxacin; Ofloxacin; Pneumonia | 2003 |
Acute urethritis caused by Neisseria meningitidis.
Topics: Acute Disease; Anti-Infective Agents, Urinary; Humans; Levofloxacin; Male; Meningococcal Infections; Middle Aged; Neisseria meningitidis; Ofloxacin; Sexually Transmitted Diseases, Bacterial; Urethritis | 2003 |
Susceptibilities to levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children: results from 2000-2001 and 2001-2002 TRUST studies in the United States.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Azithromycin; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Lactams; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Ofloxacin; Pneumococcal Infections; Prospective Studies; Respiratory Tract Infections; Streptococcus pneumoniae; Trimethoprim, Sulfamethoxazole Drug Combination; United States | 2003 |
The influence of comorbidity on the effect of levofloxacin treatment success of ambulatory respiratory tract infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Child, Preschool; Chlamydophila Infections; Chlamydophila pneumoniae; Cluster Analysis; Cohort Studies; Community-Acquired Infections; Comorbidity; Female; Haemophilus Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Respiratory Tract Infections; Treatment Outcome | 2003 |
Efficacy and pharmacodynamics of gemifloxacin versus levofloxacin in guinea pig pneumococcal pneumonia induced by strains with decreased ciprofloxacin susceptibility.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Guinea Pigs; Levofloxacin; Lung; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis | 2003 |
In vitro activity of new fluoroquinolones and linezolid against non-tuberculous mycobacteria.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Oxazolidinones; Quinolines; Spain | 2003 |
Genetic relatedness of levofloxacin-nonsusceptible Streptococcus pneumoniae isolates from North America.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Capsules; Bacterial Typing Techniques; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; Streptococcus pneumoniae | 2003 |
A third-line levofloxacin-based rescue therapy for Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agents; Benzimidazoles; Breath Tests; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Endoscopy, Digestive System; Female; Glossitis; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Penicillins; Prospective Studies; Rabeprazole; Treatment Outcome; Urea | 2003 |
In vitro evaluation of the activity of two doses of Levofloxacin alone and in combination with other agents against Pseudomonas aeruginosa.
Topics: Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Synergism; Evaluation Studies as Topic; Humans; Lactams; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Sensitivity and Specificity | 2003 |
Detection of mutations in quinolone resistance-determining regions in levofloxacin- and methicillin-resistant Staphylococcus aureus: effects of the mutations on fluoroquinolone MICs.
Topics: Anti-Infective Agents; Bacterial Proteins; Base Sequence; DNA Gyrase; Drug Resistance, Multiple; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ofloxacin; Pharmacogenetics; Polymerase Chain Reaction; Sensitivity and Specificity; Staphylococcus aureus | 2003 |
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Inhibitory activities of quinolones against DNA gyrase of Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Chlamydophila pneumoniae; DNA Gyrase; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Indoles; Levofloxacin; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Topoisomerase II Inhibitors | 2003 |
Synthesis and biological testing of non-fluorinated analogues of levofloxacin.
Topics: Animals; Anti-Infective Agents; Bacteria; Enzyme Inhibitors; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Molecular Conformation; Ofloxacin; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2003 |
Fluoroquinolone therapy in multiple-drug resistant staphylococcal keratitis after lamellar keratectomy in a rabbit model.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Keratitis; Keratomileusis, Laser In Situ; Levofloxacin; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Surgical Flaps | 2003 |
Antimicrobial susceptibilities of 40 isolates of Bacillus anthracis isolated in Turkey.
Topics: Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Ciprofloxacin; Doxycycline; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin G; Penicillins; Turkey | 2003 |
In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Genes, Bacterial; Gonorrhea; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Nalidixic Acid; Naphthyridines; Neisseria gonorrhoeae; Ofloxacin; Quinolines | 2003 |
Comparative antimicrobial activities of gatifloxacin, sitafloxacin and levofloxacin against Mycobacterium tuberculosis replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
Topics: Anti-Infective Agents; Antibiotics, Antitubercular; Cell Line; Epithelial Cells; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Macrophages; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli | 2003 |
[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
Topics: Aged; Blister; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Lung Diseases, Interstitial; Minocycline; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Pulmonary Emphysema | 2003 |
Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa.
Topics: Aminobutyrates; Aminoquinolines; Animals; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Drug Synergism; Lethal Dose 50; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Ofloxacin; Ornithine; Pseudomonas aeruginosa; Structure-Activity Relationship | 2003 |
Cefotaxime acts synergistically with levofloxacin in experimental meningitis due to penicillin-resistant pneumococci and prevents selection of levofloxacin-resistant mutants in vitro.
Topics: Animals; Anti-Infective Agents; Cefotaxime; Cephalosporins; DNA, Bacterial; Drug Resistance, Bacterial; Drug Synergism; Levofloxacin; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillin Resistance; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae | 2003 |
Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Culture Media; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae | 2003 |
Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia.
Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Humans; Immunocompromised Host; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2003 |
A novel method of estimating cost of therapy by using patient population characteristics: analysis of fluoroquinolones in various populations with different distributions of renal function.
Topics: Administration, Oral; Anti-Bacterial Agents; Aza Compounds; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoroquinolones; Formularies, Hospital as Topic; Gatifloxacin; Humans; Infusions, Intravenous; Kidney; Kidney Function Tests; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines | 2003 |
Comparative in vitro activity of three fluoroquinolones against clinical isolates by E test.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2003 |
Bactericidal activity of levofloxacin against Mycoplasma pneumoniae.
Topics: Anti-Bacterial Agents; Humans; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma | 2003 |
Antimicrobial susceptibility breakpoints and first-step parC mutations in Streptococcus pneumoniae: redefining fluoroquinolone resistance.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Streptococcus pneumoniae | 2003 |
Levofloxacin pharmacokinetics in ESRD and removal by the cellulose acetate high performance-210 hemodialyzer.
Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Cellulose; Chromatography, High Pressure Liquid; Female; Humans; Injections, Intravenous; Kidney Failure, Chronic; Levofloxacin; Male; Membranes, Artificial; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Renal Dialysis; Respiratory Tract Infections | 2003 |
Bronchoscopic microsampling method for measuring drug concentration in epithelial lining fluid.
Topics: Adult; Anti-Infective Agents; Area Under Curve; Bronchi; Bronchoscopy; Feasibility Studies; Humans; Levofloxacin; Male; Ofloxacin; Reference Values; Reproducibility of Results; Respiratory Mucosa | 2003 |
Effects of disruption of heat shock genes on susceptibility of Escherichia coli to fluoroquinolones.
Topics: Anti-Infective Agents; ATP-Dependent Proteases; Chaperonin 60; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Protease La; Rec A Recombinases; Serine Endopeptidases | 2003 |
Comparative antimicrobial activity of levofloxacin and ciprofloxacin against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Humans; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2003 |
Effect of levofloxacin coadministration on the international normalized ratios during warfarin therapy--a comment.
Topics: Anticoagulants; Drug Interactions; Drug Therapy, Combination; Humans; International Normalized Ratio; Levofloxacin; Ofloxacin; Warfarin | 2003 |
Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Carrier Proteins; Clarithromycin; Drug Resistance, Bacterial; Genes, Bacterial; Hexosyltransferases; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Mutation; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Peptidyl Transferases; Pneumococcal Infections; Streptococcus pneumoniae; Thienamycins | 2003 |
[Detection of bacterial 16S rRAN gene in EPS of men with chronic pelvic pain syndrome and its clinical significance].
Topics: Anti-Bacterial Agents; Azithromycin; Chronic Disease; Humans; Levofloxacin; Male; Ofloxacin; Pelvic Pain; Polymerase Chain Reaction; Prostatitis; RNA, Bacterial; RNA, Ribosomal, 16S | 2003 |
[Helicobacter pylori eradication based upon a drug sensitivity test effectively increased platelet count in a patient with refractory idiopathic thrombocytopenic purpura].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Ofloxacin; Omeprazole; Platelet Count; Purpura, Thrombocytopenic, Idiopathic | 2003 |
Pharmacodynamics of levofloxacin and ciprofloxacin in a murine pneumonia model: peak concentration/MIC versus area under the curve/MIC ratios.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Levofloxacin; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Protein Binding; Streptococcus pneumoniae; Survival Analysis | 2003 |
Effects of androgen deprivation on chronic bacterial prostatitis in a rat model.
Topics: Androgen Antagonists; Animals; Anti-Infective Agents, Urinary; Castration; Chronic Disease; Enzyme Inhibitors; Escherichia coli Infections; Estradiol; Estrogens; Finasteride; Levofloxacin; Male; Models, Animal; Ofloxacin; Prostatitis; Random Allocation; Rats; Rats, Wistar; Testosterone | 2003 |
[Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs].
Topics: Acute Disease; Ampicillin; Anti-Infective Agents; Azithromycin; Cefdinir; Cefpodoxime; Ceftizoxime; Cephalosporins; Clarithromycin; Enterobacteriaceae; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Penicillin G; Pharyngitis; Streptococcus pneumoniae; Streptococcus pyogenes; Tonsillitis | 2003 |
Bisacodyl rectal preparation can decrease infectious complications of transrectal ultrasound-guided prostate biopsy.
Topics: Adenocarcinoma; Administration, Oral; Administration, Rectal; Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Bacterial Infections; Biomarkers, Tumor; Biopsy, Needle; Bisacodyl; Cefixime; Epididymitis; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatitis; Retrospective Studies; Risk Factors; Ultrasonography, Interventional | 2003 |
Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones.
Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2003 |
Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides.
Topics: Acetamides; Animals; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Drug Therapy, Combination; Glycopeptides; Graft Rejection; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin | 2003 |
["Switch prophylaxis one a day" with levofloxacin in laparoscopic cholecystectomy].
Topics: Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Cholecystectomy, Laparoscopic; Drug Administration Schedule; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
Levofloxacin and trovafloxacin inhibition of experimental fracture-healing.
Topics: Animals; Anti-Infective Agents; Biomechanical Phenomena; Femoral Fractures; Fluoroquinolones; Fracture Healing; Levofloxacin; Male; Naphthyridines; Ofloxacin; Radiography; Random Allocation; Rats; Rats, Wistar | 2003 |
Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2003 |
[Use of levofloxacin in the hospital].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Drug Utilization; Female; Guideline Adherence; Hospitals, University; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Spain | 2003 |
[A study on the clinical efficacy of a combination regimen with levofloxacin and capreomycin in the treatment of multi-drug resistant pulmonary tuberculosis].
Topics: Adolescent; Adult; Antitubercular Agents; Capreomycin; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
Levofloxacin disposition in cerebrospinal fluid in patients with external ventriculostomy.
Topics: Adult; Aged; Area Under Curve; Cohort Studies; Drug Therapy, Combination; Female; Glucose; Half-Life; Humans; Hydrocephalus; Infusions, Intravenous; Leukocyte Count; Levofloxacin; Male; Middle Aged; Nervous System Diseases; Ofloxacin; Ventriculostomy | 2003 |
In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Blood Proteins; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Protein Binding; Quinolones; Rats | 2003 |
Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae | 2003 |
The effect of pharmacokinetic/pharmacodynamic (PK/PD) parameters of gatifloxacin on its bactericidal activity and resistance selectivity against clinical isolates of Streptococcus pneumoniae.
Topics: Administration, Oral; Area Under Curve; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Theoretical; Ofloxacin; Streptococcus pneumoniae | 2003 |
Polymicrobial keratitis secondary to Burkholderia ambifaria, enterococcus, and staphylococcus aureus in a patient with herpetic stromal keratitis.
Topics: Amikacin; Burkholderia; Burkholderia Infections; Corneal Stroma; Drug Therapy, Combination; Enterococcus; Eye Infections, Bacterial; Gram-Positive Bacterial Infections; Humans; Keratitis, Herpetic; Levofloxacin; Male; Middle Aged; Ofloxacin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2003 |
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones | 2003 |
[Comparative in vitro activity of garenoxacin (BMS-284756). Sentry program, Spain (1999-2000)].
Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Species Specificity; Staphylococcus aureus; Streptococcus pneumoniae | 2003 |
Effect of topical fluoroquinolones on the expression of matrix metalloproteinases in the cornea.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Blotting, Western; Ciprofloxacin; Cornea; Debridement; Female; Immunoenzyme Techniques; Levofloxacin; Matrix Metalloproteinases; Ofloxacin; Ophthalmic Solutions; Rats; Rats, Inbred Lew | 2003 |
Effect of fluoroquinolone expenditures on susceptibility of Pseudomonas aeruginosa to ciprofloxacin in U.S. hospitals.
Topics: Anti-Bacterial Agents; Benchmarking; Ciprofloxacin; Drug Costs; Drug Resistance, Bacterial; Economics, Hospital; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; United States | 2003 |
Comparative roles of levofloxacin and ofloxacin in the treatment of multidrug-resistant tuberculosis: preliminary results of a retrospective study from Hong Kong.
Topics: Anti-Infective Agents; Female; Hong Kong; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2003 |
High level of resistance to levofloxacin of Streptococcus pneumoniae following fluoroquinolone therapy.
Topics: Aged; Cefotaxime; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Follow-Up Studies; Humans; Infusions, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Risk Assessment; Severity of Illness Index; Streptococcus pneumoniae; Treatment Outcome | 2003 |
Acute hepatitis associated with levofloxacin in a patient with renal insufficiency.
Topics: Acute Disease; Alkaline Phosphatase; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Epistaxis; Female; Humans; Kidney Failure, Chronic; Levofloxacin; Middle Aged; Ofloxacin | 2003 |
Meropenem prevents levofloxacin-induced resistance in penicillin-resistant pneumococci and acts synergistically with levofloxacin in experimental meningitis.
Topics: Animals; Disease Models, Animal; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Female; Levofloxacin; Male; Meningitis, Pneumococcal; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Polymerase Chain Reaction; Rabbits; Reference Values; Sensitivity and Specificity; Streptococcus pneumoniae; Thienamycins | 2003 |
Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones.
Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2003 |
[Levofloxacin (Tavanic) in the treatment of corneal ulcers].
Topics: Administration, Oral; Anti-Infective Agents; Corneal Ulcer; Drug Administration Schedule; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Quinolones; Treatment Outcome | 2003 |
Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis.
Topics: Aged; Anti-Infective Agents; Area Under Curve; Blood Proteins; Drug Delivery Systems; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Protein Binding; Pseudomonas Infections; Sepsis; Staphylococcal Infections | 2003 |
A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin.
Topics: Aged; Anti-Infective Agents; Fatal Outcome; Female; Humans; Levofloxacin; Ofloxacin; Rhabdomyolysis | 2003 |
Bilateral Achilles tendinitis with spontaneous rupture induced by levofloxacin in a patient with systemic sclerosis.
Topics: Achilles Tendon; Cyclophosphamide; Drug Therapy, Combination; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prednisone; Risk Assessment; Rupture, Spontaneous; Scleroderma, Systemic; Severity of Illness Index; Tendinopathy | 2003 |
Levofloxacin-associated Achilles tendon rupture and tendinopathy.
Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Rupture; Tendon Injuries | 2003 |
In vitro and in vivo activity of olamufloxacin (HSR-903) against Legionella spp.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cell Line; Erythromycin; Fluoroquinolones; Guinea Pigs; Half-Life; Legionella; Legionnaires' Disease; Levofloxacin; Macrophages; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2003 |
Levofloxacin based triple therapy as a second-line treatment after failure of helicobacter pylori eradication with standard triple therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Treatment Failure | 2003 |
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Biological Transport, Active; Carrier Proteins; Drug Resistance, Microbial; Fluoroquinolones; Gene Expression Regulation, Bacterial; Lactams; Levofloxacin; Membrane Transport Proteins; Mice; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Protein Binding; Pseudomonas aeruginosa; Rats; Sepsis; Serum Albumin; Structure-Activity Relationship | 2003 |
Conversion from intravenous to oral medications: assessment of a computerized intervention for hospitalized patients.
Topics: Administration, Oral; Amiodarone; Drug Therapy, Computer-Assisted; Fluconazole; Humans; Infusions, Intravenous; Levofloxacin; Medication Systems, Hospital; Metronidazole; Ofloxacin; Practice Patterns, Physicians'; Ranitidine; Reminder Systems | 2003 |
Efficacy of vancomycin plus levofloxacin combination therapy for refractory pericarditis due to multiresistant Streptococcus pneumoniae.
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Levofloxacin; Male; Ofloxacin; Pericarditis; Pneumococcal Infections; Streptococcus pneumoniae; Vancomycin | 2003 |
[Hepatitis related to amoxicillin or levofloxacin: a case report].
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Levofloxacin; Ofloxacin | 2003 |
Determination of levofloxacin in plasma, bronchoalveolar lavage and bone tissues by high-performance liquid chromatography with ultraviolet detection using a fully automated extraction method.
Topics: Anti-Infective Agents; Automation; Bone and Bones; Bronchoalveolar Lavage Fluid; Calibration; Chromatography, High Pressure Liquid; Levofloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2004 |
Fluconazole- and levofloxacin-induced torsades de pointes in an intensive care unit patient.
Topics: Anti-Infective Agents; Antifungal Agents; Fluconazole; Humans; Intensive Care Units; Levofloxacin; Male; Middle Aged; Monitoring, Physiologic; Ofloxacin; Torsades de Pointes; United States | 2003 |
Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gonorrhea; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Ofloxacin; Prevalence; Spectinomycin; Tokyo; Urethritis | 2003 |
Efficacy of garenoxacin in treatment of experimental endocarditis due to Staphylococcus aureus or viridans group streptococci.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Endocarditis, Bacterial; Floxacillin; Fluoroquinolones; Infusions, Intravenous; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Rats; Staphylococcal Infections; Streptococcal Infections; Vancomycin; Viridans Streptococci | 2004 |
In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Topics: Anti-Infective Agents; beta-Lactamases; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Quinolones; Streptococcus pneumoniae | 2004 |
Linezolid, levofloxacin, and vancomycin against vancomycin-tolerant and fluoroquinolone-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Streptococcus pneumoniae; Vancomycin | 2003 |
The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Global Health; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Sensitivity and Specificity; Streptococcus pneumoniae | 2003 |
In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV.
Topics: Analysis of Variance; Aza Compounds; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Pharmacogenetics; Pneumococcal Infections; Probability; Quinolines; Reference Values; Regression Analysis; Sensitivity and Specificity; Streptococcus pneumoniae | 2003 |
Levofloxacin treatment failure in Haemophilus influenzae pneumonia.
Topics: Aged; Anti-Infective Agents; Community-Acquired Infections; DNA Gyrase; Electrophoresis, Gel, Pulsed-Field; Fatal Outcome; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Molecular Sequence Data; Ofloxacin; Pneumonia; Treatment Failure | 2003 |
Ceftriaxone acts synergistically with levofloxacin in experimental meningitis and reduces levofloxacin-induced resistance in penicillin-resistant pneumococci.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Drug Synergism; Levofloxacin; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae | 2004 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones | 2003 |
In vitro effect of levofloxacin and vancomycin combination against high level aminoglycoside-resistant enterococci.
Topics: Aminoglycosides; beta-Lactam Resistance; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; In Vitro Techniques; Levofloxacin; Ofloxacin; Vancomycin | 2004 |
Multiplex PCR amplimer conformation analysis for rapid detection of gyrA mutations in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; Tuberculosis | 2004 |
Immediate hypersensitivity to levofloxacin diagnosed through skin prick test.
Topics: Adult; Anti-Infective Agents; Delayed-Action Preparations; Drug Hypersensitivity; Humans; Levofloxacin; Male; Ofloxacin; Skin Tests | 2004 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
Outbreak of Clostridium difficile infection in a long-term care facility: association with gatifloxacin use.
Topics: Case-Control Studies; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; Disease Outbreaks; Drug Resistance, Bacterial; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; Humans; Levofloxacin; Long-Term Care; Microbial Sensitivity Tests; Ofloxacin | 2004 |
[Resistance of Pseudomonas aeruginosa to ciprofloxacin and levofloxacin: 1998-2002].
Topics: Body Fluids; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies | 2003 |
[A preliminary study on the definition of resistant breakpoints of ofloxacin and levofloxacin for Mycobacterium tuberculosis].
Topics: Adolescent; Adult; Aged; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Pulmonary | 2004 |
Urinary pharmacokinetics and theoretical pharmacodynamics of intravenous levofloxacin in intensive care unit patients treated with 500 mg b.i.d. for ventilator-associated pneumonia.
Topics: Adult; Aged; Biological Availability; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Probability; Respiration, Artificial; Risk Assessment; Sampling Studies; Sensitivity and Specificity; Treatment Outcome | 2003 |
Comparison of the in vitro efficacy of telithromycin (HMR 3647) and levofloxacin with 22 antibiotic compounds against Bosea and Afipia species.
Topics: Afipia; Alphaproteobacteria; Anti-Bacterial Agents; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin | 2004 |
Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors.
Topics: Aged; Cardiovascular Diseases; Female; Fluoroquinolones; Humans; Levofloxacin; Lupus Erythematosus, Systemic; Ofloxacin; Osteomyelitis; Risk Factors; Torsades de Pointes | 2004 |
Laboratory detection of Haemophilus influenzae with decreased susceptibility to nalidixic acid, ciprofloxacin, levofloxacin, and moxifloxacin due to GyrA and ParC mutations.
Topics: Aza Compounds; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Primers; DNA Topoisomerase IV; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Quinolines | 2004 |
[Use of the antibacterial agent levofloxacin for acute upper respiratory tract infection accompanied by fever (> or = 38 degrees C)].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Bacterial Agents; Body Temperature; Drug Administration Schedule; Fever; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Quality of Life; Referral and Consultation; Respiratory Tract Infections; Retrospective Studies; Treatment Outcome | 2003 |
In vitro effects of some antibiotics on glutathione reductase from sheep liver.
Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Cephalosporins; Gentamicins; Glutathione Reductase; In Vitro Techniques; Levofloxacin; Liver; Ofloxacin; Sheep; Thiamphenicol | 2003 |
Efficacy of oral levofloxacin and dirithromycin alone and in combination with rifampicin in the treatment of experimental murine Brucella abortus infection.
Topics: Animals; Anti-Bacterial Agents; Brucella abortus; Brucellosis; Drug Therapy, Combination; Erythromycin; Levofloxacin; Male; Mice; Ofloxacin; Rifampin; Treatment Outcome | 2004 |
Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis.
Topics: Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Keratitis; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus | 2004 |
[A case of pseudothrombocytopenia during antibiotic administration].
Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Fatal Outcome; Female; Humans; Levofloxacin; Lung Diseases, Interstitial; Ofloxacin; Thrombocytopenia | 2004 |
[Sporotrichoid atypical mycobacterial infections. Antibiotic monotherapy].
Topics: Adult; Biopsy; Clarithromycin; Diagnosis, Differential; Drug Resistance, Multiple, Bacterial; Female; Forearm; Hand Dermatoses; Humans; Levofloxacin; Lymphadenitis; Male; Middle Aged; Minocycline; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Ofloxacin; Skin; Skin Diseases, Bacterial; Sporotrichosis; Treatment Outcome | 2004 |
Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rats.
Topics: Acute Kidney Injury; Animals; Anti-Infective Agents; Antineoplastic Agents; Bile Ducts; Biological Availability; Blotting, Western; Caco-2 Cells; Ciprofloxacin; Cisplatin; Duodenum; Fluoroquinolones; Humans; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Piperazines; Rats; Rats, Wistar; Time Factors | 2004 |
Apparent failure of moxifloxacin to prevent ciprofloxacin- and levofloxacin-susceptible Pseudomonas aeruginosa bacteremia in neutropenic patients undergoing peripheral blood stem cell transplantation.
Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Female; Fluoroquinolones; Hematopoietic Stem Cell Transplantation; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Neutropenia; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Treatment Failure | 2004 |
[Guideline for the treatment of leprosy by new quinolones].
Topics: Anti-Infective Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Levofloxacin; Ofloxacin | 2004 |
[Achilles bilateral tendonitis and levofloxacin].
Topics: Achilles Tendon; Anti-Infective Agents; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Tendinopathy; Treatment Outcome | 2004 |
Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Body Fluids; Cells, Cultured; Colony Count, Microbial; Culture Media; DNA Topoisomerase IV; DNA, Bacterial; Epithelium; Fluoroquinolones; Genotype; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Phenotype; Quinolines; Streptococcus pneumoniae | 2004 |
[Observational study investigating the use of levofloxacin in ICU patients].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Arrhythmias, Cardiac; Bacterial Infections; Chemical and Drug Induced Liver Injury; Community-Acquired Infections; Comorbidity; Critical Care; Cross Infection; Diarrhea; Drug Resistance; Drug Therapy, Combination; Drug Utilization; Female; Humans; Infusions, Parenteral; Intensive Care Units; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Respiration, Artificial; Respiratory Tract Infections; Spain | 2004 |
Abnormal coagulation studies associated with levofloxacin. Report of three cases.
Topics: Aged; Anti-Infective Agents; Blood Coagulation Disorders; Humans; Levofloxacin; Male; Ofloxacin; Spinal Diseases | 2004 |
Mutations in the gyrA and parC genes and in vitro activities of fluoroquinolones in 91 clinical isolates of Neisseria gonorrhoeae in Japan.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gonorrhea; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Ofloxacin | 2004 |
A multidrug efflux pump inhibitor reduces fluoroquinolone resistance in Pseudomonas aeruginosa isolates.
Topics: Bacterial Outer Membrane Proteins; Ciprofloxacin; Dipeptides; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Membrane Transport Modulators; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2004 |
Comparative in vitro activities of three new quinolones and azithromycin against aerobic pathogens causing respiratory tract and abdominal wound infections.
Topics: Abdominal Injuries; Anti-Bacterial Agents; Aza Compounds; Azithromycin; Bacteria, Aerobic; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Respiratory Tract Infections; Wound Infection | 2004 |
Comparative in vitro activity of levofloxacin, ofloxacin, and ciprofloxacin against ocular streptococcal isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Endophthalmitis; Humans; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae; Viridans Streptococci | 2004 |
Tissue pharmacokinetics of levofloxacin in human soft tissue infections.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chromatography, High Pressure Liquid; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Microdialysis; Middle Aged; Ofloxacin; Soft Tissue Infections; Tissue Distribution | 2004 |
Absorption, distribution and excretion of 14C-levofloxacin after single oral administration in albino and pigmented rats: binding characteristics of levofloxacin-related radioactivity to melanin in vivo.
Topics: Albinism; Animals; Anti-Infective Agents; Area Under Curve; Carbon Radioisotopes; Chloroquine; Levofloxacin; Male; Melanins; Metabolic Clearance Rate; Ofloxacin; Pigmentation; Rats; Tissue Distribution; Uvea | 2004 |
Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Lung; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Streptococcus pneumoniae | 2004 |
In vitro activity of a novel diaminopyrimidine compound, iclaprim, against Chlamydia trachomatis and C. pneumoniae.
Topics: Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Folic Acid Antagonists; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pyrimidines | 2004 |
[Isolation-frequency and antibiotic susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa isolated in regional core hospitals in the Nagaoka district of Niigata Prefecture (changes for 3 years)].
Topics: Anti-Infective Agents; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Haemophilus influenzae; Hospitals, Urban; Humans; Japan; Levofloxacin; Ofloxacin; Penicillin G; Pseudomonas aeruginosa; Streptococcus pneumoniae; Time Factors | 2004 |
Drug costs and bacterial susceptibility after implementing a single-fluoroquinolone use policy at a university hospital.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Cost Savings; Drug Costs; Fluoroquinolones; Formularies, Hospital as Topic; Hospital Costs; Hospitals, University; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Organizational Policy | 2004 |
Monotherapy versus dual therapy for community-acquired pneumonia in hospitalized patients.
Topics: Anti-Infective Agents; Aza Compounds; Community-Acquired Infections; Doxycycline; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Hospitalization; Humans; Levofloxacin; Macrolides; Moxifloxacin; Naphthyridines; Ofloxacin; Outcome Assessment, Health Care; Pneumonia, Bacterial; Quinolines; Retrospective Studies | 2004 |
Quinolone resistance among pneumococci: therapeutic and diagnostic implications.
Topics: Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2004 |
[Resistance surveillance of common community respiratory pathogens isolated in China, 2002 - 2003].
Topics: Anti-Bacterial Agents; Cefprozil; Cephalosporins; Child, Preschool; China; Community-Acquired Infections; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Multicenter Studies as Topic; Ofloxacin; Penicillins; Respiratory Tract Infections; Streptococcus pneumoniae | 2004 |
Effectiveness of ciprofloxacin, levofloxacin, or moxifloxacin for treatment of experimental Staphylococcus aureus keratitis.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Cornea; Drug Resistance, Bacterial; Fluoroquinolones; Keratitis; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Rabbits; Staphylococcal Infections | 2004 |
In vitro activities of garenoxacin and levofloxacin against Chlamydia pneumoniae are not affected by presence of Mycoplasma DNA.
Topics: Anti-Infective Agents; Chlamydia Infections; Chlamydophila pneumoniae; Databases, Genetic; DNA, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycoplasma; Ofloxacin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal, 16S | 2004 |
Quinolone-resistant Haemophilus influenzae in a long-term care facility: clinical and molecular epidemiology.
Topics: Age Factors; Anti-Infective Agents; Case-Control Studies; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infection Control; Inhibitory Concentration 50; Levofloxacin; Long-Term Care; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Multivariate Analysis; Ofloxacin; Sex Factors | 2004 |
Levofloxacin efficacy in the treatment of community-acquired legionellosis.
Topics: Clinical Trials as Topic; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Male; Ofloxacin; Risk Assessment; Treatment Outcome | 2004 |
ABT492 and levofloxacin: comparison of their pharmacodynamics and their abilities to prevent the selection of resistant Staphylococcus aureus in an in vitro dynamic model.
Topics: Algorithms; Anti-Infective Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Half-Life; Humans; Levofloxacin; Models, Biological; Ofloxacin; Protein Binding; Quinolones; Staphylococcus aureus | 2004 |
Antimicrobial susceptibility to levofloxacin and other antibacterial agents among common respiratory pathogens-a Brazilian perspective from the GLOBAL Surveillance Initiative 2001-2002.
Topics: Anti-Bacterial Agents; Brazil; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Population Surveillance; Respiratory Tract Infections; Streptococcus pneumoniae | 2004 |
Recurrent tendinitis after treatment with two different fluoroquinolones.
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Asthma; Aza Compounds; Female; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Recurrence; Tendinopathy; Ultrasonography | 2004 |
[Levofloxacin in patients in the ICU. Factors influencing the choice of dose and its use in combined therapy].
Topics: Anti-Infective Agents; Critical Care; Drug Therapy, Combination; Humans; Infections; Intensive Care Units; Levofloxacin; Middle Aged; Ofloxacin | 2004 |
Therapeutic efficacy of moxifloxacin, a new quinolone, in the treatment of experimental intra-abdominal abscesses induced by Bacteroides fragilis in mice.
Topics: Abdominal Abscess; Animals; Anti-Bacterial Agents; Aza Compounds; Bacteroides fragilis; Bacteroides Infections; Clindamycin; Disease Models, Animal; Fluoroquinolones; Injections, Subcutaneous; Levofloxacin; Male; Metronidazole; Mice; Moxifloxacin; Ofloxacin; Quinolines | 2004 |
High-level fluoroquinolone resistance in a clinical Streptoccoccus pyogenes isolate in Germany.
Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Mutation; Ofloxacin; Polymerase Chain Reaction; Population Surveillance; Streptococcal Infections; Streptococcus pyogenes; Wound Infection | 2004 |
Effects of fluoroquinolones on the migration of human phagocytes through Chlamydia pneumoniae-infected and tumor necrosis factor alpha-stimulated endothelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Movement; Chemokines; Chlamydia; Endothelial Cells; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Monocytes; Moxifloxacin; Neutrophils; Ofloxacin; Phagocytes; Pneumonia, Bacterial; Quinolines; Stimulation, Chemical; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
In vitro activity of parenteral Beta-lactams, levofloxacin and tobramycin alone or in combination against extended-spectrum Beta-lactamase producing Klebsiella pneumoniae.
Topics: beta-Lactamases; beta-Lactams; Drug Therapy, Combination; Infusions, Parenteral; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tobramycin | 2004 |
[Mitigated erysipelas after implantation of foreign material].
Topics: Aged; Anti-Infective Agents; Arthroplasty, Replacement; Arthroplasty, Replacement, Hip; Disease Progression; Erysipelas; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteoarthritis; Osteoarthritis, Hip; Postoperative Complications; Prostheses and Implants; Prosthesis Implantation; Prosthesis-Related Infections; Reoperation; Shoulder Joint; Topoisomerase II Inhibitors | 2004 |
Levofloxacin: a suitable option for the infectious disease consultant.
Topics: Anti-Bacterial Agents; Communicable Diseases; Critical Illness; Cross Infection; Humans; Intensive Care Units; Levofloxacin; Ofloxacin; Referral and Consultation; Sensitivity and Specificity | 2004 |
Aqueous penetration of gatifloxacin and levofloxacin into the rabbit aqueous humor following topical dosing.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Chromatography, High Pressure Liquid; Fluoroquinolones; Gatifloxacin; Instillation, Drug; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Reference Standards | 2004 |
Pharmacodynamics and bactericidal activity of gatifloxacin in experimental pneumonia caused by penicillin-resistant Streptococcus pneumoniae.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Levofloxacin; Lung; Mice; Mice, Inbred CBA; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Survival Rate | 2004 |
Comparative assessment of ocular tissue distribution of drug-related radioactivity after chronic oral administration of 14C-levofloxacin and 14C-chloroquine in pigmented rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Antimalarials; Chemistry, Pharmaceutical; Chloroquine; Levofloxacin; Male; Ofloxacin; Rats; Tissue Distribution; Uvea | 2004 |
Quantitative comparison of fluoroquinolone therapies of experimental gram-negative bacterial keratitis.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Cornea; Eye Infections, Bacterial; Fluoroquinolones; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Rabbits; Serratia Infections; Serratia marcescens | 2004 |
Streptococcus pneumoniae in vitro development of resistance to amoxicillin/clavulanic acid, cefaclor, levofloxacin and azithromycin.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Azithromycin; Cefaclor; Culture Media; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 2004 |
Urinary concentrations and bactericidal activities of newer fluoroquinolones in healthy volunteers.
Topics: Adult; Anti-Infective Agents; Aza Compounds; Enterobacteriaceae; Enterococcus faecalis; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines | 2004 |
Short Communication: Yersinia pseudotuberculosis septicemia in an HIV-infected patient failed HAART.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Ceftriaxone; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Sepsis; Treatment Failure; Yersinia pseudotuberculosis; Yersinia pseudotuberculosis Infections | 2004 |
Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Cells, Cultured; Fluoroquinolones; Gatifloxacin; Insulin; Insulin Secretion; Islets of Langerhans; Levofloxacin; Mice; Ofloxacin; Patch-Clamp Techniques; Potassium Channels; Quinolones | 2004 |
Novel murine model of pneumococcal pneumonia: use of temperature as a measure of disease severity to compare the efficacies of moxifloxacin and levofloxacin.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Body Temperature; Colony Count, Microbial; Disease Models, Animal; Female; Fluoroquinolones; Levofloxacin; Lung; Mice; Moxifloxacin; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Skin Temperature | 2004 |
Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Mutation; Ofloxacin; Pneumococcal Infections; Pneumococcal Vaccines; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Serotyping; Streptococcus pneumoniae; United States; Vaccines, Conjugate | 2004 |
Designing fluoroquinolone breakpoints for Streptococcus pneumoniae by using genetics instead of pharmacokinetics-pharmacodynamics.
Topics: Anti-Bacterial Agents; Aza Compounds; DNA Topoisomerases, Type II; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Monte Carlo Method; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pneumoniae | 2004 |
The incidence of Clostridium difficile-associated and non-C. difficile-associated diarrhea after use of gatifloxacin and levofloxacin in an acute-care facility.
Topics: Clostridioides difficile; Clostridium Infections; Diarrhea; Emergency Medical Services; Fluoroquinolones; Gatifloxacin; Humans; Incidence; Levofloxacin; Ofloxacin | 2004 |
Simultaneous determination of levofloxacin, gatifloxacin and moxifloxacin in serum by liquid chromatography with column switching.
Topics: Anti-Infective Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Fluoroquinolones; Gatifloxacin; Humans; Hydrogen-Ion Concentration; Levofloxacin; Moxifloxacin; Ofloxacin; Quality Control; Quinolines; Reference Standards; Reproducibility of Results | 2004 |
Penetration of newer quinolones in the empyema fluid.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Empyema, Pleural; Escherichia coli Infections; Fluoroquinolones; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Pleural Effusion; Quinolines; Rabbits | 2004 |
Tissue and serum levofloxacin concentrations in diabetic foot infection patients.
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Chromatography, High Pressure Liquid; Diabetic Foot; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tissue Distribution | 2004 |
Bactericidal activity of moxifloxacin against multidrug-resistant Streptoccocus pneumoniae at clinically achievable serum and epithelial lining fluid concentrations compared with three other antimicrobials.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2004 |
Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Bacterial Agents; Arrhythmias, Cardiac; Case-Control Studies; Ciprofloxacin; Clarithromycin; Cohort Studies; Community Health Planning; Databases, Factual; Drug Monitoring; Erythromycin; Humans; Italy; Levofloxacin; Miocamycin; Norfloxacin; Ofloxacin; Pharmacoepidemiology; Risk Factors | 2005 |
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical | 2004 |
E-test method for detecting antibiotic synergy against Pseudomonas aeruginosa from neutropenic patients: a cost-effective approach.
Topics: Anemia; Anti-Bacterial Agents; Cefotaxime; Ceftriaxone; Cost-Benefit Analysis; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Hematologic Neoplasms; Humans; Levofloxacin; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections | 2004 |
Spectrophotometric determination of some fluoroquinolone antibacterials by binary complex formation with xanthene dyes.
Topics: Anti-Infective Agents; Ciprofloxacin; Eosine Yellowish-(YS); Levofloxacin; Merbromin; Norfloxacin; Ofloxacin; Spectrophotometry, Ultraviolet; Tablets | 2004 |
Regression of rectal mucosa-associated lymphoid tissue lymphoma but persistence of Helicobacter pylori infection of gastric mucosa after administration of levofloxacin: report of a case.
Topics: Anti-Infective Agents; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Intestinal Mucosa; Levofloxacin; Lymphoma; Middle Aged; Ofloxacin; Rectal Neoplasms; Treatment Outcome | 2004 |
Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Urinary tract infection caused by Aerococcus viridans, a case report.
Topics: Aged; Aged, 80 and over; Bacteremia; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Ofloxacin; Streptococcaceae; Urinary Tract Infections | 2004 |
High levels of dual resistance to clarithromycin and metronidazole and in vitro activity of levofloxacin against Helicobacter pylori isolates from patients after failure of therapy.
Topics: Clarithromycin; Drug Resistance; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Nitroimidazoles; Ofloxacin; Proton Pump Inhibitors; Treatment Failure | 2004 |
The effect of adsorption, filter material and point of dilution on antibiotic elimination by haemofiltration an in vitro study of levofloxacin.
Topics: Hemodiafiltration; Hemofiltration; Humans; In Vitro Techniques; Levofloxacin; Membranes, Artificial; Ofloxacin; Renal Replacement Therapy | 2004 |
Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000 mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP).
Topics: Adolescent; Adult; Aged; Area Under Curve; Community-Acquired Infections; Drug Administration Routes; Female; Hospitalization; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Ofloxacin; Streptococcus pneumoniae | 2004 |
Action of fluoroquinolones and Linezolid on logarithmic- and stationary-phase culture of Mycobacterium tuberculosis.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Culture Media; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Quinolines; Rifampin; Structure-Activity Relationship; Time Factors | 2004 |
Prevalence and molecular analysis of macrolide and fluoroquinolone resistance among isolates of Streptococcus pneumoniae collected during the 2000-2001 PROTEKT US Study.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Community-Acquired Infections; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Humans; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prevalence; Respiratory Tract Infections; Streptococcus pneumoniae; United States | 2004 |
Validation of the use of Middlebrook 7H10 agar, BACTEC MGIT 960, and BACTEC 460 12B media for testing the susceptibility of Mycobacterium tuberculosis to levofloxacin.
Topics: Agar; Anti-Bacterial Agents; Bacteriological Techniques; Culture Media; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Pulmonary | 2004 |
Effect of levofloxacin on the viability of intracellular Chlamydia pneumoniae and modulation of proinflammatory cytokine production by human monocytes.
Topics: Anti-Bacterial Agents; Cell Line; Chlamydophila pneumoniae; Cytokines; Hepatocytes; Humans; Levofloxacin; Monocytes; Ofloxacin | 2004 |
Decreased levofloxacin susceptibility in Haemophilus influenzae in children, Hong Kong.
Topics: Anti-Bacterial Agents; Carrier State; Child; Child, Preschool; Drug Resistance, Bacterial; Haemophilus influenzae; Hong Kong; Humans; Infant; Levofloxacin; Nalidixic Acid; Nasopharynx; Ofloxacin | 2004 |
[Clinical observation on treatment of retreated positive tubercle bacillus pneumoconio-tuberculosis with levofloxacin].
Topics: Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumoconiosis; Tuberculosis, Pulmonary | 2004 |
Glucocorticoids increase in vitro and in vivo activities of antibiotics against Chlamydophila pneumoniae.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromycin; Cell Line; Chlamydophila Infections; Chlamydophila pneumoniae; Dexamethasone; Drug Synergism; Glucocorticoids; Humans; Ketolides; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Ofloxacin | 2004 |
Fatal hypoglycemia associated with levofloxacin.
Topics: Aged; Fatal Outcome; Humans; Hypoglycemia; Levofloxacin; Male; Ofloxacin | 2004 |
Rupture of multiple tendons after levofloxacin therapy.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Ofloxacin; Risk Factors; Rupture; Tendon Injuries | 2004 |
Bacteriostatic and bactericidal activity of levofloxacin against clinical isolates from cystic fibrosis patients.
Topics: Anti-Bacterial Agents; Burkholderia cepacia; Cystic Fibrosis; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus | 2004 |
Relationship between increased levofloxacin use and decreased susceptibility of Streptococcus pneumoniae in the United States.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2005 |
Mycoplasma hominis septic arthritis in a pediatric renal transplant recipient: case report and review of the literature.
Topics: Adolescent; Arthritis, Infectious; Doxycycline; Edema; Female; Graft Survival; Hip; Humans; Immunocompromised Host; Immunosuppressive Agents; Inflammation; Kidney Transplantation; Levofloxacin; Magnetic Resonance Imaging; Mycophenolic Acid; Mycoplasma hominis; Ofloxacin; Pelvis; Prednisone; Radiography; Tacrolimus; Treatment Outcome | 2005 |
Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended-spectrum beta-lactamases.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Klebsiella pneumoniae; Lactams; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Ofloxacin; Thienamycins | 2004 |
Missed Achilles tendon rupture due to oral levofloxacin: surgical treatment and result.
Topics: Achilles Tendon; Administration, Oral; Anti-Bacterial Agents; Diagnostic Errors; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Orthopedic Procedures; Pneumonia, Bacterial; Rupture; Treatment Outcome | 2005 |
The interaction between levofloxacine hydrochloride and DNA mediated by Cu2+.
Topics: Animals; Anti-Bacterial Agents; Cattle; Copper; DNA; In Vitro Techniques; Levofloxacin; Nucleic Acid Denaturation; Ofloxacin; Osmolar Concentration; Spectrometry, Fluorescence; Temperature | 2004 |
The molecular epidemiology of Streptococcus pneumoniae with quinolone resistance mutations.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Population Surveillance; Serotyping; Streptococcus pneumoniae; Time Factors; United States | 2005 |
Stability and compatibility of levofloxacin and metronidazole during simulated and actual Y-site administration.
Topics: Chemistry, Pharmaceutical; Dosage Forms; Drug Incompatibility; Drug Stability; Humans; Infusions, Intravenous; Levofloxacin; Metronidazole; Ofloxacin; Temperature; Time Factors | 2005 |
In vivo activity of gemifloxacin, moxifloxacin and levofloxacin against pneumococci with gyrA and parC point mutations in a sepsis mouse model measured with the all or nothing mortality end-point.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Levofloxacin; Mice; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Point Mutation; Quinolines; Sepsis; Streptococcus pneumoniae; Treatment Outcome | 2005 |
Use of an efflux pump inhibitor to determine the prevalence of efflux pump-mediated fluoroquinolone resistance and multidrug resistance in Pseudomonas aeruginosa.
Topics: Adult; Anti-Bacterial Agents; Child; Dipeptides; Drug Resistance, Multiple, Bacterial; Drug Synergism; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Phenotype; Pseudomonas aeruginosa; Quinolines; Terminology as Topic | 2005 |
Levofloxacin plus metronidazole administered once daily versus moxifloxacin monotherapy against a mixed infection of Escherichia coli and Bacteroides fragilis in an in vitro pharmacodynamic model.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacteroides fragilis; Bacteroides Infections; Chromatography, High Pressure Liquid; Colony Count, Microbial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Half-Life; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Quinolines | 2005 |
Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States.
Topics: Anti-Bacterial Agents; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gene Transfer, Horizontal; Levofloxacin; Ofloxacin; Pneumococcal Infections; Recombination, Genetic; Streptococcus pneumoniae; United States; Viridans Streptococci | 2005 |
Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Structure-Activity Relationship | 2005 |
QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine.
Topics: Anti-Infective Agents, Urinary; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Drug Synergism; Female; Fluoxetine; Humans; Imipramine; Levofloxacin; Long QT Syndrome; Middle Aged; Ofloxacin | 2005 |
[Efficacy of levofloxacin in the treatment of acute exacerbation of chronic bronchitis in patients with risk factors].
Topics: Acute Disease; Anti-Bacterial Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Humans; Levofloxacin; Ofloxacin; Risk Factors | 2004 |
Effects of selected antibiotics on pancreatitis induced liver and pulmonary injury.
Topics: Acute Disease; Alanine Transaminase; Amylases; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Imipenem; L-Lactate Dehydrogenase; Levofloxacin; Liver; Liver Diseases; Lung; Lung Diseases; Male; Nitric Oxide; Ofloxacin; Pancreatitis; Rats; Rats, Wistar | 2005 |
High rate of coadministration of di- or tri-valent cation-containing compounds with oral fluoroquinolones: risk factors and potential implications.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cations; Cations, Divalent; Drug Antagonism; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pharmaceutical Preparations; Polypharmacy; Risk Factors; Treatment Failure | 2005 |
PSA decrease after levofloxacin therapy in patients with histological prostatitis.
Topics: Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate-Specific Antigen; Prostatitis; Retrospective Studies | 2004 |
Levofloxacin-induced delirium.
Topics: Aged; Anti-Bacterial Agents; Delirium; Humans; Levofloxacin; Male; Ofloxacin | 2005 |
[Evaluation of levofloxacin susceptibility against strains isolated from lower urinary tract infections in the community].
Topics: Anti-Infective Agents, Urinary; Bacterial Infections; Community-Acquired Infections; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Staphylococcus aureus; Urinary Tract Infections | 2005 |
Levofloxacin-imipenem combination prevents the emergence of resistance among clinical isolates of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2005 |
Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Azithromycin; Clavulanic Acid; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae | 2005 |
Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cell Line, Tumor; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Listeria monocytogenes; Macrophages; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus; Time Factors | 2005 |
[Clinical study of male urethritis in Oogaki Municipal Hospital].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Chlamydia Infections; Fluoroquinolones; Gonorrhea; Hospitals, Municipal; Humans; Japan; Levofloxacin; Male; Middle Aged; Minocycline; Naphthyridines; Ofloxacin; Sexual Partners; Sexually Transmitted Diseases, Bacterial; Spectinomycin; Urethritis | 2005 |
Influence of flow rate on the disposition of levofloxacin and netilmicin in the isolated rat lung.
Topics: Animals; In Vitro Techniques; Levofloxacin; Lung; Male; Netilmicin; Ofloxacin; Perfusion; Rats; Rats, Wistar | 2005 |
[Determination of Levofloxacin by chemiluminescence method].
Topics: Calibration; Flow Injection Analysis; Hydrogen Peroxide; Levofloxacin; Limit of Detection; Luminescence; Luminescent Measurements; Luminol; Ofloxacin; Pharmaceutical Preparations | 2004 |
Retrospective evaluation of a possible interaction between warfarin and levofloxacin.
Topics: Aged; Body Temperature; Data Collection; Drug Administration Schedule; Drug Interactions; Drug Prescriptions; Drug Therapy, Combination; Felodipine; Female; Humans; International Normalized Ratio; Levofloxacin; Male; Medical Records; Middle Aged; Ofloxacin; Outpatients; Randomized Controlled Trials as Topic; Retrospective Studies; Time Factors; Treatment Outcome; Warfarin | 2005 |
Levofloxacin secretion in breast milk: a case report.
Topics: Administration, Oral; Adult; Breast Feeding; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Levofloxacin; Milk, Human; Ofloxacin; Risk Assessment | 2005 |
In vitro activity of levofloxacin against recent Gram-negative nosocomial pathogens.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2005 |
New once-daily, highly effective rescue triple therapy after multiple Helicobacter pylori treatment failures: a pilot study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Benzimidazoles; Drug Combinations; Female; Furazolidone; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Pilot Projects; Rabeprazole; Treatment Outcome | 2005 |
[Partial bilateral rupture of the Achilles tendon associated to levofloxacin].
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Ofloxacin; Rupture, Spontaneous | 2005 |
Mutant prevention concentrations of ABT-492, levofloxacin, moxifloxacin, and gatifloxacin against three common respiratory pathogens.
Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 2005 |
A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use.
Topics: Anti-Bacterial Agents; Case-Control Studies; Cause of Death; Clindamycin; Clostridioides difficile; Cross Infection; Diarrhea; Disease Outbreaks; Enterocolitis, Pseudomembranous; Female; Fluoroquinolones; Hospitals, Teaching; Humans; Levofloxacin; Logistic Models; Male; Ofloxacin; Pennsylvania; Retrospective Studies; Risk Factors | 2005 |
An economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed care.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Community-Acquired Infections; Databases as Topic; Erythromycin; Female; Health Care Costs; Humans; Levofloxacin; Male; Managed Care Programs; Middle Aged; Models, Econometric; Ofloxacin; Pneumonia, Bacterial; Retrospective Studies; Risk Assessment; Treatment Outcome | 2005 |
Comparison of in vitro susceptibilities to levofloxacin and ciprofloxacin with Pseudomonas aeruginosa and Stenotrophomonas maltophilia isolated from cystic fibrosis patients in Northern Ireland.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Child; Ciprofloxacin; Cystic Fibrosis; Female; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Stenotrophomonas maltophilia | 2005 |
Generalized seizure and toxic epidermal necrolysis following levofloxacin exposure.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Female; Humans; Levofloxacin; Ofloxacin; Seizures; Stevens-Johnson Syndrome | 2005 |
[The clinical study on efficacy of clarithromycin, levofloxacin, and streptomycin for pulmonary Mycobacterium avium-intracellulare complex infection].
Topics: Aged; Anti-Bacterial Agents; Blood Sedimentation; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Ofloxacin; Radiography, Thoracic; Retrospective Studies; Streptomycin | 2005 |
[Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Quinolones | 2005 |
Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Streptococcus pneumoniae; Time Factors | 2005 |
[In vitro susceptibilites to levofloxacin and various antibacterial agents of 11,475 clinical isolates obtained from 52 centers in 2002].
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus | 2005 |
Characterization of fluoroquinolone and carbapenem susceptibilities in clinical isolates of levofloxacin-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Carbapenems; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Porins; Pseudomonas aeruginosa; Pseudomonas Infections | 2005 |
Rahnella aquatilis bacteremia from a suspected urinary source.
Topics: Aged; Anti-Bacterial Agents; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Prostatic Hyperplasia; Pyelonephritis; Rahnella | 2005 |
Levofloxacin-related seizure activity in a patient with Alzheimer's disease: assessment of potential risk factors.
Topics: Aged; Alzheimer Disease; Humans; Levofloxacin; Male; Ofloxacin; Risk Factors; Seizures; Urologic Diseases | 2005 |
Levofloxacin-induced fatal toxic epidermal necrolysis.
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Fatal Outcome; Humans; Levofloxacin; Male; Ofloxacin; Stevens-Johnson Syndrome; Time Factors | 2005 |
Acute localized exanthematous pustulosis secondary to levofloxacin.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Drug Eruptions; Exanthema; Humans; Levofloxacin; Male; Ofloxacin; Skin Diseases, Vesiculobullous | 2005 |
[Failure of levofloxacin therapy in two cases of community-acquired pneumonia caused by fluoroquinolone-resistant Streptococcus pneumoniae and complicated with empyema].
Topics: Aged; Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2005 |
Pharmacokinetics and pharmacodynamics of levofloxacin in intensive care patients.
Topics: Aged; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Computer Simulation; Critical Care; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Monte Carlo Method; Ofloxacin; Prospective Studies; Regression Analysis | 2005 |
Pharmacodynamic modeling of the evolution of levofloxacin resistance in Staphylococcus aureus.
Topics: Anti-Infective Agents; DNA Gyrase; Drug Resistance, Bacterial; Evolution, Molecular; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Models, Biological; Mutation; Ofloxacin; Staphylococcus aureus | 2005 |
Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages.
Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Ciprofloxacin; Fluoroquinolones; Heat-Shock Response; Humans; Kinetics; Levofloxacin; Macrophages; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2005 |
An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureus.
Topics: Adult; Anti-Bacterial Agents; Cefazolin; Clindamycin; Community-Acquired Infections; Erythromycin; Female; Humans; Kentucky; Levofloxacin; Male; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Oxacillin; Rifampin; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Sulfamethoxazole; Tetracycline; Trimethoprim; Vancomycin | 2005 |
In vitro selection of resistance to clarithromycin in Streptococcus pneumoniae clinical isolates.
Topics: Amoxicillin; Aza Compounds; Azithromycin; Clarithromycin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Sampling Studies; Sensitivity and Specificity; Streptococcus pneumoniae | 2005 |
Multiple fixed drug eruption due to drug combination.
Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caffeine; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Patch Tests; Promethazine; Salicylamides | 2005 |
Antibacterial activities of gemifloxacin, levofloxacin, gatifloxacin, moxifloxacin and erythromycin against intracellular Legionella pneumophila and Legionella micdadei in human monocytes.
Topics: Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Drug; Erythromycin; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Legionella; Legionella pneumophila; Levofloxacin; Microbial Sensitivity Tests; Monocytes; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines | 2005 |
A 10-day levofloxacin-based triple therapy in patients who have failed two eradication courses.
Topics: Amoxicillin; Anti-Bacterial Agents; Drug Evaluation; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Prospective Studies; Treatment Outcome | 2005 |
Therapeutic options among broad-spectrum beta-lactams for infections caused by levofloxacin-nonsusceptible Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactams; Community-Acquired Infections; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Pneumococcal; Polymerase Chain Reaction; Respiratory Tract Infections; Streptococcus pneumoniae | 2005 |
In vitro selection of resistance in Pseudomonas aeruginosa and Acinetobacter spp. by levofloxacin and ciprofloxacin alone and in combination with beta-lactams and amikacin.
Topics: Acinetobacter; Amikacin; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa | 2005 |
Comparative study of the disposition of levofloxacin, netilmicin and cefepime in the isolated rat lung.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Kinetics; Levofloxacin; Lung; Male; Netilmicin; Ofloxacin; Organ Culture Techniques; Rats; Rats, Wistar; Respiration, Artificial; Tissue Distribution | 2005 |
Specific antibodies, levofloxacin, and modulation of capsule-associated virulence in Streptococcus pneumoniae.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Area Under Curve; Bacterial Capsules; Female; Humans; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; Virulence | 2005 |
Levofloxacin for treatment of ventilator-associated pneumonia: putting the cart before the horse.
Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Ventilators, Mechanical | 2005 |
Levofloxacin and macrolides for treatment of Legionnaires disease: multiple comparisons give few answers.
Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Legionnaires' Disease; Levofloxacin; Macrolides; Ofloxacin | 2005 |
Simple extractive colorimetric determination of levofloxacin by acid-dye complexation methods in pharmaceutical preparations.
Topics: Acids; Anti-Bacterial Agents; Colorimetry; Coloring Agents; Levofloxacin; Ofloxacin; Pharmaceutical Preparations; Reproducibility of Results; Tablets | 2005 |
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Quinolones | 2005 |
In vivo development of high-level fluoroquinolone resistance in Streptococcus pneumoniae in chronic obstructive pulmonary disease.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Pulmonary Disease, Chronic Obstructive; Serotyping; Streptococcus pneumoniae | 2005 |
Kocuria kristinae infection associated with acute cholecystitis.
Topics: Acute Disease; Anti-Bacterial Agents; Cholecystitis; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Micrococcaceae; Middle Aged; Ofloxacin | 2005 |
[Uroinfections and the possibilities of therapy with levofloxacin].
Topics: Anti-Infective Agents, Urinary; Drug Administration Schedule; Genital Diseases, Male; Humans; Levofloxacin; Male; Ofloxacin; Treatment Outcome; Urinary Tract Infections; Urine | 2004 |
Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae.
Topics: Adult; Aged; Community-Acquired Infections; Drug Administration Schedule; Epidemiologic Methods; Fluoroquinolones; Gatifloxacin; Hospitalization; Humans; Levofloxacin; Middle Aged; Monte Carlo Method; Ofloxacin; Pneumococcal Infections; Predictive Value of Tests; Streptococcus pneumoniae | 2005 |
Preincubation of pneumococci with beta-lactams alone or combined with levofloxacin prevents quinolone-induced resistance without increasing intracellular levels of levofloxacin.
Topics: Anti-Infective Agents; beta-Lactams; Colony Count, Microbial; Culture Media; Drug Interactions; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Streptococcus pneumoniae | 2005 |
The risk of overanticoagulation with antibiotic use in outpatients on stable warfarin regimens.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Anticoagulants; Azithromycin; Cohort Studies; Drug Interactions; Female; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Platelet Aggregation Inhibitors; Prazosin; Retrospective Studies; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin | 2005 |
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Models, Chemical; Models, Statistical; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Quinolones; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Temperature; Time Factors | 2006 |
The selection of resistance to and the mutagenicity of different fluoroquinolones in Staphylococcus aureus and Streptococcus pneumoniae.
Topics: Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Moxifloxacin; Mutagenicity Tests; Naphthyridines; Ofloxacin; Quinolines; Selection, Genetic; Staphylococcus aureus; Streptococcus pneumoniae | 2005 |
Characterisation of fluoroquinolone-resistant clinical isolates of Streptococcus pyogenes in Barcelona, Spain.
Topics: Amino Acid Substitution; Anti-Infective Agents; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Carrier Proteins; Ciprofloxacin; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Molecular Epidemiology; Molecular Sequence Data; Ofloxacin; Spain; Streptococcal Infections; Streptococcus pyogenes | 2005 |
Fluoroquinolone therapy in Mycobacterium chelonae keratitis after lamellar keratectomy.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Transplantation; Disease Models, Animal; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Keratitis; Levofloxacin; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Ofloxacin; Rabbits | 2005 |
Levofloxacin-induced acute fulminant hepatic failure in a patient with chronic hepatitis B infection.
Topics: Anti-Bacterial Agents; Fatal Outcome; Female; Hepatic Encephalopathy; Hepatitis B, Chronic; Humans; Levofloxacin; Liver; Middle Aged; Ofloxacin; Respiratory Tract Infections | 2005 |
[In vitro activity of linezolid, moxifloxacin, levofloxacin, clindamycin and rifampin, alone and in combination, against Staphylococcus aureus and Staphylococcus epidermidis].
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Clindamycin; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Oxazolidinones; Quinolines; Rifampin; Staphylococcus aureus; Staphylococcus epidermidis | 2005 |
Anaphylaxis due to levofloxacin.
Topics: Adult; Anaphylaxis; Animals; Brachyura; Food Hypersensitivity; Humans; Intradermal Tests; Levofloxacin; Male; Meat; Ofloxacin; Patch Tests | 2005 |
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2005 |
Transfer of ciprofloxacin, ofloxacin and levofloxacin across the perfused human placenta in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Female; Fetus; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Placenta; Pregnancy; Pregnancy Complications, Infectious | 2005 |
Coadministration of oral levofloxacin with agents that impair its absorption: potential impact on emergence of resistance.
Topics: Administration, Oral; Adsorption; Aged; Anti-Bacterial Agents; Case-Control Studies; Cations, Divalent; Drug Interactions; Drug Resistance, Bacterial; Drug Therapy, Combination; Elements; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Staphylococcal Infections; Staphylococcus; Time Factors | 2005 |
Evaluation of moxifloxacin, ciprofloxacin, gatifloxacin, ofloxacin, and levofloxacin concentrations in human conjunctival tissue.
Topics: Anti-Bacterial Agents; Aza Compounds; Biopsy; Ciprofloxacin; Conjunctiva; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tissue Distribution | 2005 |
Distribution of fluoroquinolone MICs in Helicobacter pylori strains from Korean patients.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Korea; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Point Mutation; Quinolines; Sequence Analysis, DNA | 2005 |
Levofloxacin treatment of active tuberculosis and the risk of adverse events.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antitubercular Agents; Case-Control Studies; Child; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis | 2005 |
Uncommon occurrence of fluoroquinolone resistance-associated alterations in GyrA and ParC in clinical strains of Chlamydia trachomatis.
Topics: Amino Acid Sequence; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Ofloxacin; Urethritis | 2004 |
Pharmacodynamic analysis of ceftriaxone, gatifloxacin,and levofloxacin against Streptococcus pneumoniae with the use of Monte Carlo simulation.
Topics: Anti-Bacterial Agents; Area Under Curve; Ceftriaxone; Computer Simulation; Databases, Factual; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intravenous; Levofloxacin; Microbial Sensitivity Tests; Monte Carlo Method; Ofloxacin; Streptococcus pneumoniae | 2005 |
In vitro and in vivo synergy of levofloxacin or amikacin both in combination with ceftazidime against clinical isolates of Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Ceftazidime; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Sensitivity and Specificity | 2005 |
Synergistic potential of ceftazidime plus amikacin or levofloxacin against Pseudomonas aeruginosa as determined using a checkerboard and a disk diffusion technique.
Topics: Amikacin; Anti-Infective Agents; Ceftazidime; Drug Synergism; Drug Therapy, Combination; Immunodiffusion; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2005 |
Ciprofloxacin, but not levofloxacin, affects cyclosporine blood levels in a patient with pure red blood cell aplasia.
Topics: Adult; Ciprofloxacin; Cyclosporine; Humans; Levofloxacin; Male; Ofloxacin; Red-Cell Aplasia, Pure | 2005 |
Rescue therapy with levofloxacin after multiple H. pylori treatment failures.
Topics: Anti-Bacterial Agents; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Treatment Failure | 2005 |
Hypoglycemia in inpatients after gatifloxacin or levofloxacin therapy: nested case-control study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Case-Control Studies; Female; Fluoroquinolones; Gatifloxacin; Humans; Hypoglycemia; Levofloxacin; Male; Middle Aged; Ofloxacin; Risk Factors | 2005 |
A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Ceftriaxone; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Male; Middle Aged; Ofloxacin; Product Surveillance, Postmarketing; Retrospective Studies | 2005 |
Pharmacokinetics of intravenously administered levofloxacin in men and women.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Prospective Studies; Regression Analysis; Sex Characteristics | 2005 |
In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactams; Carbapenems; Doripenem; Ertapenem; Humans; Imipenem; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Thienamycins | 2005 |
[Tendinitis associated with levofloxacin].
Topics: Achilles Tendon; Anti-Bacterial Agents; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tendinopathy; Time Factors | 2005 |
Glucose homeostasis abnormalities associated with use of gatifloxacin.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Child; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Glucose; Homeostasis; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines | 2005 |
Use of a three-dimensional microarray system for detection of levofloxacin resistance and the mec A gene in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Oligonucleotide Array Sequence Analysis; Penicillin-Binding Proteins; Polymerase Chain Reaction; Sequence Analysis, DNA; Staphylococcus aureus | 2005 |
Reduced levofloxacin susceptibility and tetracycline resistance in a clinical isolate of Haemophilus quentini identified by 16S rRNA sequencing.
Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Typing Techniques; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Haemophilus; Haemophilus Infections; Humans; Infant, Newborn; Levofloxacin; Nalidixic Acid; Ofloxacin; Phenotype; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Tetracycline Resistance | 2005 |
Microbiological rationale for the utilisation of prulifloxacin, a new fluoroquinolone, in the eradication of serious infections caused by Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cystic Fibrosis; Dioxolanes; Drug Resistance, Bacterial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Opportunistic Infections; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Quinolones | 2005 |
Systemic and local antibiotic prophylaxis in the prevention of Staphylococcus epidermidis graft infection.
Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Levofloxacin; Male; Methicillin Resistance; Ofloxacin; Polyethylene Terephthalates; Polytetrafluoroethylene; Prosthesis-Related Infections; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus epidermidis; Teicoplanin | 2005 |
Quantitative determinations of levofloxacin and rifampicin in pharmaceutical and urine samples using nuclear magnetic resonance spectroscopy.
Topics: Calibration; Dimethyl Sulfoxide; Dosage Forms; Humans; Levofloxacin; Magnetic Resonance Spectroscopy; Maleates; Models, Molecular; Molecular Conformation; Ofloxacin; Rifampin; Sensitivity and Specificity | 2005 |
An unusual cause of sepsis during pregnancy: recognizing infection with chlamydophila abortus.
Topics: Abortion, Spontaneous; Adult; Animals; Chlamydophila psittaci; Female; Goat Diseases; Goats; Humans; Levofloxacin; Macrolides; Ofloxacin; Pregnancy; Pregnancy Complications, Infectious; Psittacosis; Risk Factors; Sepsis; Zoonoses | 2005 |
Hypoglycemia-induced anoxic brain injury possibly associated with levofloxacin.
Topics: Aged; Anti-Bacterial Agents; Blood Glucose; Glasgow Coma Scale; Humans; Hypoglycemia; Hypoxia, Brain; Levofloxacin; Male; Neurologic Examination; Ofloxacin; Time Factors | 2006 |
Relationships between antimicrobial use and antimicrobial resistance in Gram-negative bacteria causing nosocomial infections from 1991-2003 at a university hospital in Taiwan.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, University; Humans; Incidence; Length of Stay; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Taiwan | 2005 |
Life-threatening meningitis resulting from transrectal prostate biopsy.
Topics: Adenocarcinoma; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biopsy; Escherichia coli Infections; Humans; Levofloxacin; Male; Meningitis; Metronidazole; Ofloxacin; Prostatic Neoplasms; Ultrasound, High-Intensity Focused, Transrectal | 2005 |
Synergistic effect of fosfomycin and fluoroquinolones against Pseudomonas aeruginosa growing in a biofilm.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Drug Synergism; Fluoroquinolones; Fosfomycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones | 2005 |
The in vitro effects of quinupristin/dalfopristin, erythromycin and levofloxacin at low concentrations on the expression of different cell adhesion molecules on the surface of endothelial cells (Eahy926).
Topics: Anti-Bacterial Agents; Cell Adhesion Molecules; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Erythromycin; Flow Cytometry; Humans; Levofloxacin; Ofloxacin; Phlebitis; Virginiamycin | 2006 |
[Results of the study on antibiotic resistance emergence among pathogens of community-acquired urinary tract infections in Moscow. Phase I].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacterial Infections; Cephalosporins; Community-Acquired Infections; Drug Resistance; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Middle Aged; Moscow; Ofloxacin; Urinary Tract Infections | 2005 |
Effective antimicrobial regimens for use in humans for therapy of Bacillus anthracis infections and postexposure prophylaxis.
Topics: Animals; Anthrax; Anti-Infective Agents; Bacillus anthracis; Humans; Levofloxacin; Macaca mulatta; Mice; Ofloxacin; Preventive Medicine | 2005 |
In vivo measurement of levofloxacin penetration into lung tissue after cardiac surgery.
Topics: Aged; Anti-Infective Agents; Area Under Curve; Coronary Artery Bypass; Dose-Response Relationship, Drug; Humans; Levofloxacin; Lung; Middle Aged; Ofloxacin; Pneumonia; Pseudomonas Infections | 2005 |
Levofloxacin and moxifloxacin increase human gut colonization by Candida species.
Topics: Anti-Infective Agents; Aza Compounds; Candida; Drug Resistance, Microbial; Fluoroquinolones; Humans; Intestines; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines | 2005 |
Failure of levofloxacin treatment in community-acquired pneumococcal pneumonia.
Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; Community-Acquired Infections; DNA Topoisomerases, Type II; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Streptolysins; Treatment Failure | 2005 |
Comparison of the minimum inhibitory, mutant prevention and minimum bactericidal concentrations of ciprofloxacin, levofloxacin and garenoxacin against enteric Gram-negative urinary tract infection pathogens.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Urinary Tract Infections | 2005 |
Safety and efficacy of levofloxacin 1.5% eyedrops in nonhuman primates having penetrating keratoplasty: clinical and laboratory findings.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Biopsy; Cornea; Dose-Response Relationship, Drug; Drug Administration Schedule; Keratoplasty, Penetrating; Levofloxacin; Macaca mulatta; Microscopy, Confocal; Ofloxacin; Ophthalmic Solutions; Photography; Postoperative Care; Preoperative Care | 2005 |
Levofloxacin in enteric fever--a study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Typhoid Fever | 2005 |
Pharmacodynamic assessment of the activity of high-dose (750 mg) levofloxacin, ciprofloxacin, and gatifloxacin against clinical strains of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; DNA, Bacterial; Evaluation Studies as Topic; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2006 |
[Pharmacokinetic/pharmacodynamic analysis to optimize antibacterial treatments: prediction of efficacy by using Montecarlo simulation techniques].
Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin | 2005 |
Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Biological Availability; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Polycystic Kidney, Autosomal Dominant; Pyelonephritis; Streptococcal Infections; Streptococcus agalactiae | 2006 |
The safety of levofloxacin in elderly patients on warfarin.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticoagulants; Case-Control Studies; Drug Interactions; Female; Hemorrhage; Humans; Levofloxacin; Male; Odds Ratio; Ofloxacin; Ontario; Thrombosis; Warfarin | 2005 |
[Fluorescence spectroscopy study of humen serum albumin quenched by levofloxacin].
Topics: Algorithms; Binding Sites; Energy Transfer; Humans; Kinetics; Levofloxacin; Models, Chemical; Ofloxacin; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Tryptophan | 2005 |
Invasive Haemophilus influenzae isolates with decreased levofloxacin susceptibility in Hong Kong.
Topics: Anti-Bacterial Agents; Haemophilus Infections; Haemophilus influenzae; Hong Kong; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies | 2006 |
Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes.
Topics: 1-Octanol; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cornea; Drug Carriers; Enoxacin; Ethylene Glycols; Eye; Fluoroquinolones; Gatifloxacin; In Vitro Techniques; Irritants; Levofloxacin; Ofloxacin; Oxaprozin; Permeability; Propionates; Rabbits; Ribavirin; Water | 2006 |
Effectiveness of fluoroquinolones against Mycobacterium abscessus in vivo.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Corneal Ulcer; Disease Models, Animal; Eye Infections, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Ofloxacin; Ophthalmic Solutions; Quinolines; Rabbits | 2006 |
Mutant prevention concentration for ciprofloxacin and levofloxacin with Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa | 2006 |
Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003).
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States | 2006 |
[Assessment of the management of community-acquired pneumonia in adults outpatients].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Amoxicillin; Anti-Bacterial Agents; Chi-Square Distribution; Clarithromycin; Community-Acquired Infections; Emergencies; Female; Frail Elderly; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Prospective Studies; Treatment Failure | 2005 |
Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?
Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Studies; Humans; Levofloxacin; Long QT Syndrome; Male; Ofloxacin; Prognosis; Prospective Studies; Prostatitis; Respiratory Tract Infections; Severity of Illness Index; Urinary Tract Infections | 2006 |
Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: a retrospective database analysis of treatment duration, outcomes, and charges.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Aza Compounds; Database Management Systems; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies; Sinusitis; Treatment Outcome; United States | 2006 |
Comparative study of antimicrobial release kinetics from polymethylmethacrylate.
Topics: Acetamides; Anti-Bacterial Agents; Area Under Curve; Cefazolin; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones; Polymethyl Methacrylate; Rifampin | 2006 |
Pharmacokinetic interaction between levofloxacin and ciclosporin or tacrolimus in kidney transplant recipients: ciclosporin, tacrolimus and levofloxacin in renal transplantation.
Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Clinical Trials as Topic; Cyclosporine; Drug Interactions; Female; Graft Rejection; Half-Life; Humans; Immunosuppressive Agents; Kidney Transplantation; Levofloxacin; Male; Ofloxacin; Tacrolimus; Transplantation Immunology | 2006 |
In vitro activity of levofloxacin against Helicobacter pylori isolates from patients after treatment failure.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Drug Utilization; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Treatment Failure | 2006 |
Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration.
Topics: Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Mutation; Naphthyridines; Ofloxacin; Pneumococcal Infections; Serum Bactericidal Test; Streptococcus pneumoniae; Treatment Outcome | 2006 |
Outpatient gatifloxacin therapy and dysglycemia in older adults.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Case-Control Studies; Cephalosporins; Diabetes Complications; Female; Fluoroquinolones; Gatifloxacin; Hospitalization; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Macrolides; Male; Ofloxacin; Ontario; Risk | 2006 |
Levofloxacin/imipenem prevents the emergence of high-level resistance among Pseudomonas aeruginosa strains already lacking susceptibility to one or both drugs.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Synergism; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2006 |
Pharmacodynamics of moxifloxacin and levofloxacin simulating human serum and lung concentrations.
Topics: Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Humans; Klebsiella pneumoniae; Levofloxacin; Lung; Models, Biological; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus; Streptococcus pneumoniae | 2005 |
Correlation between in vitro and in vivo activity of levofloxacin and moxifloxacin against pneumococcal strains with different susceptibilities to fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Colony Count, Microbial; Disease Models, Animal; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Mice; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae; Survival Analysis | 2006 |
Factors influencing the intracellular activity of fluoroquinolones: a study using levofloxacin in a Staphylococcus aureus THP-1 monocyte model.
Topics: Anti-Bacterial Agents; Cell Line; Culture Media; Humans; Levofloxacin; Microbial Sensitivity Tests; Monocytes; Ofloxacin; Staphylococcus aureus | 2006 |
Validation of a levofloxacin HPLC assay in plasma and dialysate for pharmacokinetic studies.
Topics: Anti-Bacterial Agents; Aza Compounds; Chromatography, High Pressure Liquid; Dialysis Solutions; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Renal Dialysis; Reproducibility of Results | 2006 |
Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States.
Topics: Adult; Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Long-Term Care; Microbial Sensitivity Tests; Middle Aged; Mutation; Ofloxacin; Streptococcus pneumoniae | 2006 |
In-vitro activity of quinupristin/dalfopristin, levofloxacin and moxifloxacin against fusidic acid and rifampicin-resistant strains of methicillin-resistant Staphylococcus aureus (MRSA) from Malaysian hospitals.
Topics: Anti-Bacterial Agents; Aza Compounds; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Fusidic Acid; Humans; In Vitro Techniques; Levofloxacin; Malaysia; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Rifampin; Staphylococcus aureus; Virginiamycin | 2005 |
Clinical efficacy and tolerability of levofloxacin in patients with liver disease: a prospective, non comparative, observational study.
Topics: Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Drug Tolerance; Female; Humans; Levofloxacin; Liver Diseases; Male; Middle Aged; Ofloxacin; Peritonitis; Pneumonia; Prospective Studies; Urinary Tract Infections | 2006 |
Levofloxacin-based rescue regimens after Helicobacter pylori treatment failure: how strong is the evidence?
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Treatment Failure | 2006 |
Determination of the newer quinolones levofloxacin and moxifloxacin in plasma by high-performance liquid chromatography with fluorescence detection.
Topics: Anti-Bacterial Agents; Aza Compounds; Chromatography, High Pressure Liquid; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2006 |
[A case of takotsubo cardiomyopathy provoked by taking a new quinolone antibiotic drug and a non-steroidal anti-inflammatory drug].
Topics: Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiomyopathies; Electrocardiography; Fatty Acids; Female; Fluorodeoxyglucose F18; Humans; Iodine Radioisotopes; Iodobenzenes; Levofloxacin; Ofloxacin; Phenylpropionates; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2006 |
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution | 2006 |
Pharmacodynamics of levofloxacin against Pseudomonas aeruginosa with reduced susceptibility due to different efflux pumps: do elevated MICs always predict reduced in vivo efficacy?
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Outer Membrane Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gene Deletion; Genes, Bacterial; Levofloxacin; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Pseudomonas aeruginosa; Sepsis | 2006 |
[Prevalence and treatment of pharyngeal Chlamydia trachomatis infections].
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Clarithromycin; Female; Humans; Japan; Levofloxacin; Ofloxacin; Pharyngitis; Prevalence; Sex Work; Sexual Behavior; Uterine Diseases | 2006 |
[Levofloxacin-induced tendon rupture with fatal outcome].
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Comorbidity; Fatal Outcome; Humans; Levofloxacin; Male; Ofloxacin; Pneumothorax; Pulmonary Disease, Chronic Obstructive; Rib Fractures; Rupture, Spontaneous; Subcutaneous Emphysema; Tendinopathy | 2006 |
Re: treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Humans; Levofloxacin; Male; Ofloxacin; Prostate-Specific Antigen; Prostatitis | 2006 |
[In vitro antituberculous activity of ofloxacin and levofloxacin against multidrug-resistant tuberculosis and clinical outcomes].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Drug Resistance, Multiple, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2006 |
Detection of live and antibiotic-killed bacteria by quantitative real-time PCR of specific fragments of rRNA.
Topics: Anti-Bacterial Agents; Colony Count, Microbial; DNA, Bacterial; Genes, Bacterial; Genetic Markers; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillins; Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal; RNA, Ribosomal, 16S; Streptococcus | 2006 |
Levofloxacin pharmacokinetics and pharmacodynamics in patients with severe burn injury.
Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Burns; Computer Simulation; Female; Half-Life; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Ofloxacin; Treatment Outcome | 2006 |
Antipneumococcal activity of DW-224a, a new quinolone, compared to those of eight other agents.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Azithromycin; Cefuroxime; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genes, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2006 |
Using interrupted time series analysis to assess associations of fluoroquinolone formulary changes with susceptibility of gram-negative pathogens and isolation rates of methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Escherichia coli; Fluoroquinolones; Formularies as Topic; Gatifloxacin; Gram-Negative Bacteria; Humans; Levofloxacin; Methicillin; Methicillin Resistance; Ofloxacin; Pseudomonas aeruginosa; Regression Analysis; Retrospective Studies; Staphylococcus aureus | 2006 |
Differential effects of levofloxacin and ciprofloxacin on the risk for isolation of quinolone-resistant Pseudomonas aeruginosa.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Case-Control Studies; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Levofloxacin; Male; Middle Aged; Ofloxacin; Pseudomonas Infections; Quinolones; Regression Analysis; Retrospective Studies; Risk Factors | 2006 |
Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Azithromycin; Ceftazidime; Colistin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins; Tobramycin | 2006 |
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Rabbits; Staphylococcal Infections; Vitreous Body | 2007 |
Phenotypic and genotypic characterization of fecal Escherichia coli isolates with decreased susceptibility to fluoroquinolones: results from a large hospital-based surveillance initiative.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Feces; Fluoroquinolones; Genotype; Hospitals; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Phenotype; Population Surveillance; Solvents | 2006 |
In vitro activity of fluoroquinolones against common respiratory pathogens.
Topics: Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2006 |
Levofloxacin-induced hypoglycemia in a nondiabetic patient.
Topics: Aged; Anti-Bacterial Agents; Coronary Artery Bypass; Female; Glucagon; Glucose; Humans; Hypoglycemia; Infusions, Intravenous; Insulin; Insulin Secretion; Insulin-Secreting Cells; Levofloxacin; Ofloxacin; Pneumonia | 2006 |
A pharmacodynamic approach to antimicrobial activity in serum and epithelial lining fluid against in vivo-selected Streptococcus pneumoniae mutants and association with clinical failure in pneumonia.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Quinolines; Serum Bactericidal Test; Streptococcus pneumoniae | 2006 |
Quinolones sensitize gram-negative bacteria to antimicrobial peptides.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2006 |
A Rare but serious side effect of Levofloxacin: hypoglycemia in a geriatric patient.
Topics: Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemia; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia; Urinary Tract Infections | 2006 |
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].
Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood | 2006 |
Intrapulmonary pharmacokinetics and pharmacodynamics of high-dose levofloxacin in healthy volunteer subjects.
Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Bacteria; Bronchoalveolar Lavage Fluid; Bronchoscopy; Female; Humans; Levofloxacin; Lung; Male; Microbial Sensitivity Tests; Ofloxacin | 2006 |
[Clinical efficacy and cost benefit of oral antimicrobial prophylaxis with levofloxacin on neurological surgery].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cost-Benefit Analysis; Female; Humans; Levofloxacin; Male; Middle Aged; Neurosurgical Procedures; Ofloxacin; Postoperative Complications; Surgical Wound Infection | 2006 |
Superantigen gene profile, emm type and antibiotic resistance genes among group A streptococcal isolates from Barcelona, Spain.
Topics: Alleles; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance; Erythromycin; Genes, Bacterial; Genetic Variation; Hospitals; Humans; Levofloxacin; Medical Records; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Ofloxacin; Pneumococcal Infections; Retrospective Studies; Spain; Species Specificity; Streptococcus pyogenes; Superantigens; Tetracycline; Urban Population | 2006 |
Effect of drug concentration on adsorption of levofloxacin by polyacrylonitrile haemofilters.
Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Hemofiltration; Humans; Levofloxacin; Models, Biological; Ofloxacin; Renal Insufficiency | 2006 |
Continuous versus intermittent levofloxacin treatment in complicated urinary tract infections caused by urinary obstruction temporarily relieved by foreign body insertion.
Topics: Anti-Infective Agents, Urinary; Biofilms; Drug Administration Schedule; Female; Foreign Bodies; Humans; Levofloxacin; Male; Ofloxacin; Stents; Urethral Obstruction; Urinary Tract Infections | 2006 |
Evaluation of bacterial kill when modelling the bronchopulmonary pharmacokinetic profile of moxifloxacin and levofloxacin against parC-containing isolates of Streptococcus pneumoniae.
Topics: Adult; Area Under Curve; Aza Compounds; Bronchi; Computer Simulation; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Genotype; Humans; Levofloxacin; Lung; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2006 |
Levofloxacin induced myasthenia crisis.
Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Male; Middle Aged; Myasthenia Gravis; Ofloxacin; Respiratory Insufficiency; Thymoma; Tomography, X-Ray Computed; Treatment Outcome | 2006 |
[The efficacy of levofloxacin based triple therapy for Helicobacter pylori eradication].
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2006 |
Effects of antibacterial agents, levofloxacin and clarithromycin, on aquatic organisms.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Clarithromycin; Crustacea; Daphnia; Dose-Response Relationship, Drug; Environmental Pollutants; Levofloxacin; Models, Chemical; Ofloxacin; Risk; Toxicity Tests, Acute; Water Pollutants, Chemical; Water Purification | 2006 |
Occurrence of levofloxacin, clarithromycin and azithromycin in wastewater treatment plant in Japan.
Topics: Anti-Bacterial Agents; Azithromycin; Chromatography, Liquid; Clarithromycin; Conservation of Natural Resources; Japan; Levofloxacin; Mass Spectrometry; Ofloxacin; Sewage; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2006 |
Pharmacokinetics, metabolism, excretion and plasma protein binding of 14C-levofloxacin after a single oral administration in the Rhesus monkey.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Blood Proteins; Carbon Radioisotopes; Female; Levofloxacin; Macaca mulatta; Male; Ofloxacin; Protein Binding | 2006 |
Moxifloxacin prophylaxis in neutropenic patients.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Bacteremia; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Moxifloxacin; Neutropenia; Ofloxacin; Quinolines | 2006 |
Treatment of acute post-surgical infection of joint arthroplasty.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bacterial Infections; Debridement; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Male; Ofloxacin; Prosthesis-Related Infections; Rifampin; Treatment Outcome | 2006 |
Role of the preliminary susceptibility testing for initial and after failed therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and esomeprazole.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Bacterial Proteins; Breath Tests; Drug Resistance, Bacterial; Drug Therapy, Combination; Endoscopy, Digestive System; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Treatment Outcome; Urease | 2006 |
Primary levofloxacin resistance and gyrA/B mutations among Helicobacter pylori in Japan.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Ofloxacin; Sequence Analysis, DNA | 2006 |
Enhanced activity of rifalazil in combination with levofloxacin, linezolid, or mupirocin against Staphylococcus aureus in vitro.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Mupirocin; Ofloxacin; Oxazolidinones; Rifamycins; Staphylococcus aureus | 2006 |
Pancytopenia with levofloxacin therapy for pelvic inflammatory disease in an otherwise healthy young patient.
Topics: Adult; Female; Humans; Levofloxacin; Ofloxacin; Pancytopenia; Pelvic Inflammatory Disease | 2006 |
Flow-injection chemiluminescence determination of ofloxacin and levofloxacin in pharmaceutical preparations and biological fluids.
Topics: Anti-Infective Agents, Urinary; Cerium; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Flow Injection Analysis; Humans; Levofloxacin; Luminescence; Models, Chemical; Ofloxacin; Pharmaceutical Preparations; Sensitivity and Specificity; Urinalysis | 2006 |
Call for the international adoption of microbiological breakpoints for fluoroquinolones and Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Point Mutation; Streptococcus pneumoniae | 2006 |
Respiratory tract infections: at-risk patients, who are they? Implications for their management with levofloxacin.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Risk Factors | 2006 |
Levofloxacin-induced delirium: Diagnostic considerations.
Topics: Anti-Bacterial Agents; Delirium; Electroencephalography; Humans; Levofloxacin; Ofloxacin; Status Epilepticus | 2006 |
Triple levofloxacin-based rescue therapy is an accepted empirical third-line treatment.
Topics: Amoxicillin; Ampicillin; Antacids; Anti-Bacterial Agents; Bismuth; Breath Tests; Clarithromycin; Drug Therapy, Combination; Enzyme Inhibitors; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Ofloxacin; Omeprazole; Protein Synthesis Inhibitors; Tetracycline; Treatment Failure | 2006 |
X-Ray crystallographic, NMR and antimicrobial activity studies of magnesium complexes of fluoroquinolones - racemic ofloxacin and its S-form, levofloxacin.
Topics: Anti-Infective Agents; Bacteria; Crystallography, X-Ray; Fluoroquinolones; Levofloxacin; Magnesium; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Ofloxacin; Stereoisomerism | 2006 |
Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Horses; Humans; Injections, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae | 2006 |
Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease?
Topics: Aged; Aged, 80 and over; Aza Compounds; Case-Control Studies; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines | 2006 |
Fluoroquinolone resistance in Salmonella typhi and S. paratyphi A in Bangalore, India.
Topics: Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Salmonella paratyphi A; Salmonella typhi | 2007 |
Successful treatment of a widespread cutaneous Mycobacterium fortuitum infection with levofloxacin.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Mycobacterium; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Skin Diseases, Bacterial; Treatment Outcome | 2006 |
A community-based study of Helicobacter pylori therapy using the strategy of test, treat, retest, and re-treat initial treatment failures.
Topics: Anti-Bacterial Agents; Delivery of Health Care; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Failure; Treatment Outcome | 2006 |
Levofloxacin and rhabdomyolysis in a renal transplant patient.
Topics: Aged; Anti-Bacterial Agents; Humans; Kidney Transplantation; Levofloxacin; Male; Ofloxacin; Rhabdomyolysis | 2006 |
Susceptibility testing of clinical isolates of pseudomonas aeruginosa to levofloxacin, moxifloxacin, and gatifloxacin as a guide to treating pseudomonas ocular infections.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines | 2006 |
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: exploration of aromatic substituents.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Outer Membrane Proteins; Levofloxacin; Lung; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pyrimidines; Rats; Rats, Sprague-Dawley | 2006 |
In vivo selection during ofloxacin therapy of Escherichia coli with combined topoisomerase mutations that confer high resistance to ofloxacin but susceptibility to nalidixic acid.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; DNA Topoisomerases; Drug Resistance; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Male; Nalidixic Acid; Ofloxacin | 2006 |
Anticoagulation-related outcomes in patients receiving warfarin after starting levofloxacin or gatifloxacin.
Topics: Aged; Anticoagulants; Databases as Topic; Drug Monitoring; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Hospitals, Veterans; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome; United States; Warfarin | 2006 |
Computational and experimental approaches for assessing the interactions between the model calycin beta-lactoglobulin and two antibacterial fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Binding Sites; Cattle; Computational Biology; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Levofloxacin; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Norfloxacin; Ofloxacin; Thermodynamics | 2006 |
[Antibiotic resistance in Streptococcus pneumoniae strains isolated from sterile body sites].
Topics: Anti-Bacterial Agents; Bacteremia; Cerebrospinal Fluid; Dacryocystitis; Drug Resistance, Bacterial; Ear, Middle; Erythromycin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pleural Effusion; Pneumococcal Infections; Streptococcus pneumoniae; Synovial Fluid; Wound Infection | 2006 |
Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cloxacillin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Foreign-Body Reaction; Humans; Levofloxacin; Linezolid; Male; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
Prevalence and natural history of colonization with fluoroquinolone-resistant gram-negative bacilli in community-dwelling people with spinal cord dysfunction.
Topics: Anti-Bacterial Agents; Carrier State; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Gram-Negative Aerobic Bacteria; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Perineum; Prevalence; Prospective Studies; Spinal Cord Diseases; Urinary Catheterization; Urinary Incontinence; Urinary Tract Infections | 2006 |
Application of two methods to determine killing of Streptococcus pneumoniae by various fluoroquinolones.
Topics: Anti-Bacterial Agents; Aza Compounds; Cells, Cultured; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2006 |
Effect of levofloxacin on serum glucose concentration in rats.
Topics: Adrenal Medulla; Animals; Anti-Bacterial Agents; Blood Glucose; Diphenhydramine; Dose-Response Relationship, Drug; Epinephrine; Histamine; Histamine H1 Antagonists; Histamine Release; Hyperglycemia; Hypoglycemia; In Vitro Techniques; Insulin; Levofloxacin; Male; Ofloxacin; Rats; Rats, Wistar; Time Factors | 2006 |
Synthesis and antibacterial activity of nitroaryl thiadiazole-levofloxacin hybrids.
Topics: Anti-Bacterial Agents; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Structure-Activity Relationship; Thiadiazoles | 2006 |
Clinical application of levofloxacin for severe infections.
Topics: Anti-Infective Agents; Humans; Infections; Levofloxacin; Ofloxacin; Severity of Illness Index | 2006 |
In vitro activity of sitafloxacin against clinical strains of Streptococcus pneumoniae with defined amino acid substitutions in QRDRs of gyrase A and topoisomerase IV.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Sequence Analysis, DNA; Streptococcus pneumoniae | 2006 |
[A case of Mycobacterium fortuitum meningitis following surgery for meningioma].
Topics: Clarithromycin; Female; Humans; Levofloxacin; Meningeal Neoplasms; Meningioma; Meningitis, Bacterial; Middle Aged; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Postoperative Complications | 2006 |
In vitro development of resistance to DX-619 and other quinolones in enterococci.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Polymerase Chain Reaction; Pyrrolidines; Quinolines; Quinolones; Sequence Analysis, DNA | 2006 |
Altered spectrum of multidrug resistance associated with a single point mutation in the Escherichia coli RND-type MDR efflux pump YhiV (MdtF).
Topics: Acetamides; Alleles; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; DNA, Bacterial; DNA, Complementary; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Levofloxacin; Linezolid; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Ofloxacin; Oxazolidinones; Phenotype; Phenylalanine; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial | 2007 |
Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model.
Topics: Aerosols; Animals; Anthrax; Anti-Bacterial Agents; Area Under Curve; Bacillus anthracis; Computer Simulation; Dose-Response Relationship, Drug; Drug Compounding; Female; Humans; Inhalation Exposure; Levofloxacin; Macaca mulatta; Male; Microbial Sensitivity Tests; Ofloxacin; Spores, Bacterial | 2006 |
Conservative treatment of staphylococcal prosthetic joint infections in elderly patients.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Chi-Square Distribution; Debridement; Drug Administration Schedule; Female; Hip Prosthesis; Humans; Joint Prosthesis; Knee Prosthesis; Levofloxacin; Male; Methicillin Resistance; Ofloxacin; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Treatment Failure; Treatment Outcome | 2006 |
Interactions of fluoroquinolone antibacterials, DX-619 and levofloxacin, with creatinine transport by renal organic cation transporter hOCT2.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Cell Line; Creatinine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Levofloxacin; Molecular Structure; Ofloxacin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrrolidines; Quinolones; Transfection | 2006 |
The mutant selection window in rabbits infected with Staphylococcus aureus.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Colony Count, Microbial; Diffusion Chambers, Culture; Drug Resistance, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Selection, Genetic; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 2006 |
Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aza Compounds; Bacterial Proteins; Canada; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Serotyping; Streptococcus pneumoniae | 2007 |
Penetration of levofloxacin into paranasal sinuses mucosa of patients with chronic rhinosinusitis after a single 500 mg oral dose.
Topics: Adult; Aged; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Levofloxacin; Male; Middle Aged; Mucous Membrane; Ofloxacin; Paranasal Sinuses; Rhinitis; Sinusitis | 2007 |
In vitro activity of linezolid in combination with doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin against methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Enzyme Inhibitors; Fosfomycin; Humans; In Vitro Techniques; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
[Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium].
Topics: Aged; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Female; Gentamicins; Gram-Positive Bacterial Infections; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Teicoplanin; Virginiamycin | 2006 |
Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Cattle; Half-Life; Injections, Intramuscular; Levofloxacin; Male; Ofloxacin | 2006 |
Effect of quinupristin/dalfopristin on 3T3 and Eahy926 cells in vitro in comparison to other antimicrobial agents with the potential to induce infusion phlebitis.
Topics: Animals; Anti-Bacterial Agents; BALB 3T3 Cells; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Erythromycin; Fibroblasts; Humans; Infusions, Intravenous; Inhibitory Concentration 50; Levofloxacin; Mice; No-Observed-Adverse-Effect Level; Ofloxacin; Phlebitis; Reproducibility of Results; Toxicity Tests; Virginiamycin | 2007 |
Screening and its potential application of lipolytic activity from a marine environment: characterization of a novel esterase from Yarrowia lipolytica CL180.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA, Fungal; Enzyme Stability; Escherichia coli; Esterases; Genomic Library; Hydrogen-Ion Concentration; Levofloxacin; Lipolysis; Molecular Sequence Data; Molecular Weight; Ofloxacin; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Stereoisomerism; Substrate Specificity; Temperature; Water Microbiology; Yarrowia | 2007 |
Levofloxacin-induced interstitial nephritis and vasculitis in an elderly woman.
Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Bacterial Agents; Fatal Outcome; Female; Humans; Levofloxacin; Myelodysplastic Syndromes; Nephritis, Interstitial; Ofloxacin; Purpura; Urinary Tract Infections; Vasculitis | 2006 |
Severe Legionnaires' disease successfully treated with levofloxacin and azithromycin.
Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Azithromycin; Drug Therapy, Combination; Female; Humans; Legionnaires' Disease; Levofloxacin; Lung; Middle Aged; Ofloxacin; Radiography; Remission Induction | 2006 |
Biofilm formation on hydrophilic intraocular lens material.
Topics: Acrylic Resins; Animals; Bacterial Adhesion; Biofilms; Colony Count, Microbial; Drug Carriers; Enterococcus faecalis; Fluoroquinolones; Gatifloxacin; Hydrogel, Polyethylene Glycol Dimethacrylate; Lenses, Intraocular; Levofloxacin; Microscopy, Electron, Scanning; Ofloxacin; Polymethyl Methacrylate; Rabbits; Staphylococcus epidermidis | 2006 |
The relationship between previous fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin | 2007 |
Establishment of an animal model with side effects induced by mycophenolate mofetil and pharmacohistological analysis of them.
Topics: Animals; Body Weight; Diarrhea; Energy Intake; Feeding Behavior; Immunosuppressive Agents; Levofloxacin; Male; Mice; Mice, Inbred BALB C; Models, Animal; Mycophenolic Acid; Ofloxacin; Weight Loss | 2006 |
[Efficacy and safety of levofloxacin treatment of community--acquired pneumonia in hospitalized patients].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Female; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Radiography; Treatment Outcome | 2006 |
Effectiveness of an aggressive antibiotic regimen for chemoembolization in patients with previous biliary intervention.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biliary Tract Diseases; Case-Control Studies; Chemoembolization, Therapeutic; Drainage; Drug Therapy, Combination; Erythromycin; Humans; Levofloxacin; Liver Abscess; Liver Function Tests; Metronidazole; Neomycin; Ofloxacin; Retrospective Studies; Risk Factors; Stents | 2006 |
Dissociation between inhibition and killing by levofloxacin in human granulocytic anaplasmosis.
Topics: Aged; Anaplasma phagocytophilum; Anaplasmosis; Animals; Anti-Bacterial Agents; Disease Models, Animal; Female; Humans; Levofloxacin; Male; Mice; Mice, SCID; Ofloxacin; Recurrence; Treatment Outcome | 2006 |
Photophysical and phototoxic properties of the antibacterial fluoroquinolones levofloxacin and moxifloxacin.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Radiation; Erythrocytes; Fluoroquinolones; Humans; Levofloxacin; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Photolysis; Photosensitizing Agents; Quinolines; Ultraviolet Rays | 2004 |
Successful treatment of Klebsiella rhinoscleromatis bacteremia with levofloxacin.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Ofloxacin | 2007 |
[Study investigating the activity of several fluoroquinolones against Pseudomonas aeruginosa using the mutant prevention concentration].
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutagenicity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines | 2006 |
Evaluation of an intracellular pharmacokinetic in vitro infection model as a tool to assess tuberculosis therapy.
Topics: Antitubercular Agents; Cell Line; Half-Life; Humans; Isoniazid; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin | 2007 |
Penetration of levofloxacin into the anterior chamber (aqueous humour) of the human eye after intravenous administration.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Female; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Ofloxacin | 2007 |
[A case of drug-induced pneumonitis due to levofloxacin and kampo medicine].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Female; Humans; Levofloxacin; Medicine, Kampo; Middle Aged; Ofloxacin; Pneumonia; Sinusitis | 2006 |
[Musculoskeletal adverse effects of levofloxacin].
Topics: Anti-Bacterial Agents; Arthralgia; Arthritis; Arthritis, Infectious; Arthroplasty, Replacement, Knee; Atorvastatin; Combined Modality Therapy; Debridement; Diagnosis, Differential; Doxycycline; Drug Interactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Levofloxacin; Middle Aged; Ofloxacin; Postoperative Complications; Prosthesis-Related Infections; Pyrroles; Recurrence; Reoperation; Rifampin; Thyroiditis, Autoimmune; Thyroxine; Trimethoprim, Sulfamethoxazole Drug Combination | 2006 |
Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant Streptococcus pneumoniae by time-kill methodology.
Topics: Anti-Bacterial Agents; Humans; In Vitro Techniques; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae | 2007 |
Post-marketing surveillance of the safety of levofloxacin in Japan.
Topics: Achilles Tendon; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Chemical and Drug Induced Liver Injury; Female; Humans; Hypoglycemia; Japan; Levofloxacin; Liver Diseases; Long QT Syndrome; Male; Middle Aged; Ofloxacin; Photosensitivity Disorders; Product Surveillance, Postmarketing; Seizures; Torsades de Pointes | 2007 |
Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: attempts to control a new epidemic strain.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Clostridioides difficile; Cross Infection; Disease Outbreaks; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Risk Factors | 2007 |
Short-course therapy of gemifloxacin effective against pneumococcal pneumonia in mice.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Body Temperature; Colony Count, Microbial; Disease Models, Animal; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Lung; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Mutation, Missense; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome | 2006 |
Detection of parC mutations in Streptococcus pneumoniae by Real-time PCR and Taqman-MGB probes.
Topics: Anti-Infective Agents; Aspartic Acid; Codon; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Bacterial; Levofloxacin; Mutation; Ofloxacin; Oligonucleotide Probes; Pneumococcal Infections; Polymerase Chain Reaction; Serine; Streptococcus pneumoniae; Taq Polymerase | 2007 |
Disposition kinetics, urinary excretion and dosage regimen of levofloxacin formulation following single intravenous administration in crossbred calves.
Topics: Animals; Anti-Bacterial Agents; Cattle; Drug Administration Schedule; Injections, Intravenous; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Time Factors | 2007 |
Fluoroquinolone resistance in Streptococcus pneumoniae: area under the concentration-time curve/MIC ratio and resistance development with gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin.
Topics: Area Under Curve; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae | 2007 |
Biphasic regulation of levofloxacin on lipopolysaccharide-induced IL-1beta production.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Gene Expression Regulation; Immunologic Factors; Interleukin-1beta; Levofloxacin; Lipopolysaccharides; Macrophages; Mice; Ofloxacin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
[In-vitro and in-vivo activities of moxifloxacin and garenoxacin against Mycobacterium leprae].
Topics: Animals; Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Leprostatic Agents; Levofloxacin; Mice; Mice, Inbred BALB C; Mice, Nude; Moxifloxacin; Mycobacterium leprae; Ofloxacin; Quinolines; Rifampin | 2007 |
Synthesis and antibacterial activity of levofloxacin derivatives with certain bulky residues on piperazine ring.
Topics: Anti-Bacterial Agents; Levofloxacin; Molecular Structure; Ofloxacin; Structure-Activity Relationship | 2007 |
Antimicrobial resistance trends among sinus isolates of Streptococcus pneumoniae in the United States (2001-2005).
Topics: Acetamides; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactam Resistance; Cefuroxime; Cephalosporin Resistance; Clindamycin; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Levofloxacin; Linezolid; Ofloxacin; Oxazolidinones; Paranasal Sinuses; Penicillin Resistance; Population Surveillance; Streptococcus pneumoniae; Trimethoprim Resistance; Trimethoprim, Sulfamethoxazole Drug Combination; United States | 2007 |
Antibacterial effects of moxifloxacin and levofloxacin simulating epithelial lining fluid concentrations against community-acquired methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Aza Compounds; Community-Acquired Infections; Culture Media; Epithelium; Fluoroquinolones; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2007 |
Delayed intraocular foreign body removal without endophthalmitis during Operations Iraqi Freedom and Enduring Freedom.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Combined Modality Therapy; Endophthalmitis; Eye Enucleation; Eye Foreign Bodies; Eye Injuries, Penetrating; Female; Fluoroquinolones; Follow-Up Studies; Humans; Iraq; Levofloxacin; Male; Middle Aged; Military Medicine; Military Personnel; Moxifloxacin; Ofloxacin; Postoperative Complications; Prognosis; Quinolines; Retrospective Studies; Risk Factors; Time Factors; Visual Acuity; Vitrectomy; Vitreoretinopathy, Proliferative; Warfare | 2007 |
Penetration of topically applied levofloxacin into eyes with thin-wall filtering bleb after trabeculectomy.
Topics: Adult; Aged; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Eye Infections, Bacterial; Female; Filtering Surgery; Humans; Intraocular Pressure; Levofloxacin; Male; Middle Aged; Ofloxacin; Trabeculectomy | 2008 |
[Bilophila wadsworthia isolated from surgical specimens].
Topics: Anti-Bacterial Agents; beta-Lactams; Bilophila; Ciprofloxacin; Clindamycin; Digestive System Surgical Procedures; Drug Resistance, Bacterial; Humans; Japan; Levofloxacin; Minocycline; Ofloxacin; Peritonitis; Postoperative Complications; Specimen Handling; Surgical Wound Infection | 2006 |
Factors compromising the activity of moxifloxacin against intracellular Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Aza Compounds; Cell Line; Extracellular Space; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Lysosomes; Monocytes; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcal Infections; Staphylococcus aureus | 2007 |
In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance.
Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Ciprofloxacin; Dioxolanes; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Hemolysin Proteins; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Ultraviolet Rays; Urinary Tract Infections | 2007 |
Major role of levofloxacin in the treatment of a case of Listeria monocytogenes meningitis.
Topics: Aged; Anti-Bacterial Agents; Cerebrospinal Fluid; Female; Humans; Levofloxacin; Listeria monocytogenes; Listeriosis; Meningitis, Listeria; Ofloxacin; Treatment Outcome | 2007 |
Longitudinally tracking fluoroquinolone resistance and its determinants in penicillin-susceptible and -nonsusceptible Streptococcus pneumoniae isolates in Hong Kong, 2000 to 2005.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fluoroquinolones; Hong Kong; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae | 2007 |
Rapid chiral separation and impurity determination of levofloxacin by ligand-exchange chromatography.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Levofloxacin; Ligands; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Tablets | 2007 |
Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Fluoroquinolones; Heart Conduction System; In Vitro Techniques; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Rabbits; Torsades de Pointes | 2007 |
The safety of levofloxacin in patients on warfarin.
Topics: Anti-Bacterial Agents; Anticoagulants; Drug Interactions; Hemorrhage; Humans; International Normalized Ratio; Levofloxacin; Ofloxacin; Thrombosis; Warfarin | 2007 |
[Changes in intestinal microflora following levofloxacin administration in laboratory animals].
Topics: Animals; Anti-Bacterial Agents; Gram-Negative Aerobic Bacteria; Intestines; Levofloxacin; Mice; Models, Animal; Ofloxacin; Rats; Rats, Sprague-Dawley | 2005 |
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus; Urinary Tract Infections | 2006 |
Effects of acute renal failure and ganciclovir on the pharmacodynamics of levofloxacin-induced seizures in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antiviral Agents; Dose-Response Relationship, Drug; Ganciclovir; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Rats; Rats, Wistar; Seizures | 2007 |
Levofloxacin implants with predefined microstructure fabricated by three-dimensional printing technique.
Topics: Drug Implants; Levofloxacin; Microscopy, Electron, Scanning; Ofloxacin; Solubility; Technology, Pharmaceutical | 2007 |
Optimization of levofloxacin analysis by RP-HPLC using multivariate calibration technique.
Topics: Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Dosage Forms; Humans; Levofloxacin; Ofloxacin; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2007 |
Effect of recombinant human activated protein C on the bactericidal activity of human monocytes and modulation of pro-inflammatory cytokines in the presence of antimicrobial agents.
Topics: Ampicillin; Anti-Bacterial Agents; Blood Bactericidal Activity; Cytokines; Escherichia coli; Humans; In Vitro Techniques; Inflammation; Interleukin-1beta; Interleukin-8; Kinetics; Levofloxacin; Monocytes; Ofloxacin; Protein C; Recombinant Proteins; Tumor Necrosis Factor-alpha | 2007 |
Modeling of microbial population responses to time-periodic concentrations of antimicrobial agents.
Topics: Anti-Infective Agents; Klebsiella pneumoniae; Levofloxacin; Microbial Viability; Models, Biological; Models, Theoretical; Ofloxacin; Pseudomonas aeruginosa | 2007 |
Antimicrobial efficacy of gatifloxacin and moxifloxacin with and without benzalkonium chloride compared with ciprofloxacin and levofloxacin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Aza Compounds; Benzalkonium Compounds; Cells, Cultured; Ciprofloxacin; Drug Combinations; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Preservatives, Pharmaceutical; Quinolines; Staphylococcus aureus | 2007 |
In vitro activity of ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and gatifloxacin against multidrug-resistant Mycobacterium tuberculosis in Rio de Janeiro Brazil.
Topics: AIDS-Related Opportunistic Infections; Brazil; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 2007 |
Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Ciprofloxacin; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Female; Fluoroquinolones; Gatifloxacin; Injections, Intraperitoneal; Leptospira interrogans; Leptospirosis; Levofloxacin; Mesocricetus; Ofloxacin; Serotyping; Survival Analysis | 2007 |
Role of interleukin-6 in the pathogenesis of an avian model of Staphylococcus aureus arthritis.
Topics: Animals; Anti-Bacterial Agents; Arthritis, Infectious; Chickens; Disease Models, Animal; Interleukin-6; Levofloxacin; Ofloxacin; Staphylococcal Infections; Staphylococcus aureus | 2007 |
Efficacy of a novel rifamycin derivative, ABI-0043, against Staphylococcus aureus in an experimental model of foreign-body infection.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Drug Therapy, Combination; Foreign-Body Reaction; Guinea Pigs; Injections, Intraperitoneal; Levofloxacin; Male; Microbial Sensitivity Tests; Molecular Structure; Ofloxacin; Rifampin; Rifamycins; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 2007 |
Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; DNA, Bacterial; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Genes, Bacterial; Hospitals; Humans; Korea; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Molecular Epidemiology; Mutation; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Prevalence; Reserpine; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae | 2007 |
Inhibition of Simian virus 40 large T antigen helicase activity by fluoroquinolones.
Topics: Antigens, Polyomavirus Transforming; Antiviral Agents; Cell Line, Tumor; Ciprofloxacin; Cytopathogenic Effect, Viral; DNA Helicases; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Reproducibility of Results; Simian virus 40; Time Factors; Viral Plaque Assay; Virus Replication | 2007 |
Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Drug Resistance, Bacterial; Humans; Immunocompetence; Levofloxacin; Mice; Microbial Sensitivity Tests; Mutation; Neutropenia; Ofloxacin; Plague; Selection, Genetic; Streptomycin; Thigh; Treatment Outcome; Yersinia pestis | 2007 |
Primary antibiotic resistance in Helicobacter pylori strains isolated in northern and central Italy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Drug Resistance; Drug Resistance, Multiple, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Treatment Outcome | 2007 |
Antibacterial activity of contact lenses bearing surface-immobilized layers of intact liposomes loaded with levofloxacin.
Topics: Agar; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Colony Count, Microbial; Contact Lenses; Culture Media; Kinetics; Levofloxacin; Liposomes; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus; Surface Properties | 2007 |
Characterisation of levofloxacin-resistant clinical isolates of Streptococcus pyogenes in Bilbao, Spain.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Humans; Levofloxacin; Male; Ofloxacin; Spain; Streptococcal Infections; Streptococcus pyogenes | 2007 |
A rapid and simple high-performance liquid chromatography method for the determination of human plasma levofloxacin concentration and its application to bioequivalence studies.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Levofloxacin; Male; Ofloxacin; Prazosin; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Spectrometry, Fluorescence; Therapeutic Equivalency | 2007 |
Pharmacokinetics and pharmacodynamics of levofloxacin in critically ill patients with ventilator-associated pneumonia.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Ventilator-Associated; Prospective Studies | 2007 |
[Reduction of endotoxin may protect lung from injury in rats with hepatopulmonary syndrome].
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Endotoxins; Hepatopulmonary Syndrome; Levofloxacin; Lung; Male; Malondialdehyde; Ofloxacin; Portal Pressure; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
[Drug-resistant bacteria isolated from pharyngeal swab cultures and urine in acutely or chronically febrile elderly nursing home inmates].
Topics: Acute Disease; Aged; Chronic Disease; Drug Resistance, Bacterial; Escherichia coli; Fever; Fluoroquinolones; Humans; Levofloxacin; Nursing Homes; Ofloxacin; Penicillin Resistance; Pharynx; Staphylococcus aureus; Streptococcus pneumoniae; Urinary Tract Infections; Urine | 2007 |
Multidrug-induced erythema multiforme.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Ceftriaxone; Ciprofloxacin; Drug Hypersensitivity; Erythema Multiforme; Female; Humans; Levofloxacin; Methenamine; Ofloxacin; Piroxicam; Skin Tests; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2007 |
Comparison of antibiotic effect and corneal epithelial toxicity of levofloxacin and moxifloxacin in vitro.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacteriological Techniques; Cell Count; Cell Survival; Cells, Cultured; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Epithelium, Corneal; Fluoroquinolones; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pseudomonas aeruginosa; Quinolines; Serratia marcescens; Staphylococcus aureus | 2007 |
Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Merkel Cell; Clostridioides difficile; Cytotoxins; Diarrhea; Ear Neoplasms; Enterocolitis, Pseudomembranous; Esomeprazole; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Levofloxacin; Male; Metronidazole; Ofloxacin; Skin Neoplasms; Thyroxine; Vancomycin | 2007 |
[Antibacterial activity of tosufloxacin against major organisms detected from patients with respiratory infections].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Klebsiella pneumoniae; Levofloxacin; Moraxella catarrhalis; Naphthyridines; Ofloxacin; Pseudomonas aeruginosa; Respiratory Tract Infections; Streptococcus | 2007 |
Chromobacterium violaceum infection in Taiwan: a case report and literature review.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Chromobacterium; Female; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Ofloxacin; Taiwan; Wound Infection | 2007 |
Interaction between warfarin and levofloxacin: case series.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticoagulants; Drug Interactions; Female; Hemorrhage; Humans; Levofloxacin; Male; Ofloxacin; Pericardial Effusion; Retroperitoneal Space; Warfarin | 2007 |
Methicillin-sensitive Staphylococcus aureus tricuspid valve endocarditis with annular abscess cured with oral levofloxacin and rifampicin.
Topics: Abscess; Adult; Anti-Bacterial Agents; Cloxacillin; Endocarditis, Bacterial; Fever; Humans; Levofloxacin; Male; Methicillin Resistance; Ofloxacin; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Tricuspid Valve | 2007 |
An in vitro investigation of levofloxacin and ciprofloxacin against clinical isolates of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Humans; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates. Synthesis of levofloxacin.
Topics: Anti-Infective Agents; Benzoxazines; Levofloxacin; Ofloxacin; Stereoisomerism; Sulfonamides | 2007 |
Pharmacodynamic assessment based on mutant prevention concentrations of fluoroquinolones to prevent the emergence of resistant mutants of Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2007 |
Levofloxacin in first-line treatment of Helicobacter pylori infection.
Topics: Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Treatment Outcome | 2007 |
Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague.
Topics: Aerosols; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Doxycycline; Female; Gentamicins; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Plague; Protein Biosynthesis; Time Factors; Yersinia pestis | 2007 |
Pharmacokinetics of moxifloxacin and levofloxacin in intensive care unit patients who have acute renal failure and undergo extended daily dialysis.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Anuria; Aza Compounds; Critical Care; Critical Illness; Female; Fluoroquinolones; Humans; Intensive Care Units; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Moxifloxacin; Multiple Organ Failure; Ofloxacin; Quinolines; Renal Dialysis; Sepsis | 2006 |
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Etanercept; Fluoroquinolones; Immunoglobulin G; Inflammation; Levofloxacin; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Naphthyridines; Ofloxacin; Pentoxifylline; Receptors, Tumor Necrosis Factor; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2007 |
In vitro and in vivo activities of novel fluoroquinolones alone and in combination with clarithromycin against clinically isolated Mycobacterium avium complex strains in Japan.
Topics: Animals; Aza Compounds; Clarithromycin; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Humans; Japan; Levofloxacin; Liver; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Microbial Viability; Moxifloxacin; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolines; Spleen | 2007 |
Outbreak of Legionnaires' disease in immunosuppressed patients at a cancer centre: usefulness of universal urine antigen testing and early levofloxacin therapy.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Bacterial; Cancer Care Facilities; Cross Infection; Female; Humans; Immunocompromised Host; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Ofloxacin; Spain | 2007 |
Is it Clostridium difficile infection or something else? A case-control study of 352 hospitalized patients with new-onset diarrhea.
Topics: Aged; Analysis of Variance; Case-Control Studies; Cefazolin; Ceftriaxone; Clostridioides difficile; Confidence Intervals; Cross Infection; Diarrhea; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Hospitalization; Humans; Incidence; Levofloxacin; Male; Missouri; Multivariate Analysis; Odds Ratio; Ofloxacin; Regression Analysis; Retrospective Studies; Risk Factors | 2007 |
Effects of levofloxacin and doxycycline on interleukin-6 production of Chlamydia trachomatis-infected human synovial fibroblasts.
Topics: Cell Line; Chlamydia trachomatis; Doxycycline; Fibroblasts; Humans; Interleukin-6; Levofloxacin; Microbial Viability; Ofloxacin; Synovial Fluid | 2007 |
Intrapulmonary pharmacodynamics of high-dose levofloxacin in subjects with chronic bronchitis or chronic obstructive pulmonary disease.
Topics: Adult; Aged; Area Under Curve; Blood Chemical Analysis; Bronchitis, Chronic; Bronchoalveolar Lavage Fluid; Bronchoscopy; Chlamydophila pneumoniae; Chromatography, High Pressure Liquid; Female; Haemophilus influenzae; Humans; Levofloxacin; Male; Mass Spectrometry; Microbial Sensitivity Tests; Middle Aged; Mycoplasma pneumoniae; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Streptococcus pneumoniae; Time Factors | 2007 |
Determination of acid base balance and oil water partition coefficient of an atopy patch test of levofloxacin.
Topics: Acid-Base Equilibrium; Anti-Bacterial Agents; Drug Hypersensitivity; Humans; Levofloxacin; Ofloxacin; Patch Tests; Potentiometry; Predictive Value of Tests; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Time Factors | 2008 |
Simulated comparison of the pharmacodynamics of ciprofloxacin and levofloxacin against Pseudomonas aeruginosa using pharmacokinetic data from healthy volunteers and 2002 minimum inhibitory concentration data.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Monte Carlo Method; Ofloxacin; Pseudomonas aeruginosa | 2007 |
In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple; Ethidium; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Reserpine; Streptococcus pneumoniae | 2007 |
Pulmonary versus systemic delivery of levofloxacin. The isolated lung of the rat as experimental approach for assessing pulmonary inhalation.
Topics: Administration, Inhalation; Animals; Anti-Bacterial Agents; Body Fluids; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; In Vitro Techniques; Levofloxacin; Lung; Male; Ofloxacin; Pulmonary Alveoli; Rats; Rats, Wistar; Tissue Distribution | 2008 |
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2007 |
In vitro evaluation of antibiotics' combinations for empirical therapy of suspected methicillin resistant Staphylococcus aureus severe respiratory infections.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumonia; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin | 2007 |
[Fluoroquinolone-induced tendon diseases].
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Female; Humans; Levofloxacin; Magnetic Resonance Imaging; Male; Middle Aged; Ofloxacin; Rupture; Tendinopathy; Ultrasonography | 2007 |
In vitro pharmacodynamics of moxifloxacin versus levofloxacin against 4 strains of Streptococcus pneumoniae: 1 wild type, 2 first-step parC mutants, and 1 pump mutant.
Topics: Anti-Bacterial Agents; Aza Compounds; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Moxifloxacin; Mutation; Ofloxacin; Polymerase Chain Reaction; Quinolines; Streptococcus pneumoniae | 2008 |
[In vitro activity of levofloxacin against Escherichia coli strains in acute pyelonephritis, in France in 2005].
Topics: Acute Disease; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; France; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pyelonephritis | 2007 |
Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cohort Studies; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Gatifloxacin; Hospitals, Veterans; Humans; Hyperglycemia; Hypoglycemia; Kidney Diseases; Levofloxacin; Logistic Models; Male; Medication Errors; Ofloxacin; Retrospective Studies | 2007 |
An alternative salvage regimen for Helicobacter pylori-resistant patients with heart failure.
Topics: Amoxicillin; Anti-Bacterial Agents; Comorbidity; Drug Therapy, Combination; Heart Failure; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Proton Pump Inhibitors | 2008 |
The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo.
Topics: Biological Transport; Carnitine; Cell Line, Tumor; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Ofloxacin; Organic Cation Transport Proteins; Piperazines; Placenta; Sodium; Solute Carrier Family 22 Member 5 | 2008 |
Pharmacokinetic analysis of transcellular transport of levofloxacin across LLC-PK1 and Caco-2 cell monolayers.
Topics: Animals; Anti-Bacterial Agents; Biological Transport, Active; Caco-2 Cells; Humans; Hydrogen-Ion Concentration; Levofloxacin; LLC-PK1 Cells; Metabolic Clearance Rate; Models, Theoretical; Ofloxacin; Swine | 2007 |
Serum bactericidal activities of moxifloxacin and levofloxacin against aerobic and anaerobic intra-abdominal pathogens.
Topics: Abdominal Cavity; Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria, Aerobic; Bacteria, Anaerobic; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Serum Bactericidal Test | 2008 |
Clearance of levofloxacin by an in vitro model of continuous venovenous hemodialysis (CVVHD).
Topics: Anti-Infective Agents, Urinary; Humans; Levofloxacin; Materials Testing; Membranes, Artificial; Ofloxacin; Renal Dialysis | 2007 |
Characterization and dynamics of middle ear fluid and nasopharyngeal isolates of Streptococcus pneumoniae from 12 children treated with levofloxacin.
Topics: Acute Disease; Anti-Bacterial Agents; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Levofloxacin; Nasopharynx; Ofloxacin; Otitis Media with Effusion; Pneumococcal Infections; Streptococcus pneumoniae | 2008 |
Validated HPTLC method for simultaneous estimation of levofloxacin hemihydrate and ornidazole in pharmaceutical dosage form.
Topics: Amebicides; Anti-Bacterial Agents; Calibration; Chromatography, Thin Layer; Dosage Forms; Levofloxacin; Ofloxacin; Ornidazole; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2007 |
[Bilateral achilles tendon disorders secondary to levofloxacin].
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Muscular Diseases; Ofloxacin | 2007 |
[A case of tuberculous pleurisy with a rapid decrease in pleural effusion].
Topics: Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Ofloxacin; Pleural Effusion; Tuberculosis, Pleural | 2007 |
Frequency of 1st- and 2nd-step topoisomerase mutations in Streptococcus pneumoniae following levofloxacin and moxifloxacin exposure.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Colony Count, Microbial; DNA Topoisomerases; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Moxifloxacin; Mutation, Missense; Ofloxacin; Polymerase Chain Reaction; Quinolines; Sequence Analysis, DNA; Streptococcus pneumoniae | 2008 |
[Renal parencymal malacoplakia successfully treated with conservative therapy; a case report].
Topics: Administration, Oral; Aged; Biopsy, Needle; Female; Humans; Kidney Diseases; Levofloxacin; Malacoplakia; Ofloxacin; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
Levofloxacin-resistant Helicobacter pylori in Hong Kong.
Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Helicobacter Infections; Helicobacter pylori; Hong Kong; Humans; Ketolides; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Ofloxacin; Point Mutation; Tetracycline | 2008 |
Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Creatinine; Diabetes Complications; Female; Fluoroquinolones; Gatifloxacin; Hospitals, Veterans; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Male; Medical Records; Middle Aged; Multivariate Analysis; Ofloxacin; Prevalence; Retrospective Studies; Rhode Island; Risk Factors | 2008 |
Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in young women with acute uncomplicated pyelonephritis.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Escherichia coli Infections; Female; Humans; Levofloxacin; Ofloxacin; Pyelonephritis; Serum; Time Factors; Urine | 2008 |
Intrinsic cytotoxic effects of fluoroquinolones on human corneal keratocytes and endothelial cells.
Topics: Anti-Bacterial Agents; Aza Compounds; Biological Assay; Ciprofloxacin; Cornea; Corneal Stroma; Endothelial Cells; Endothelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines | 2008 |
Fatal hypoglycemia with levofloxacin use in an elderly patient in the post-operative period.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Duodenal Ulcer; Fatal Outcome; Humans; Hyperinsulinism; Hypoglycemia; Infusions, Intravenous; Levofloxacin; Male; Ofloxacin; Peptic Ulcer Perforation; Peritonitis; Postoperative Care; Postoperative Complications; Recurrence | 2008 |
Simultaneous determination of rifampicin and levofloxacin concentrations in catheter segments from a mouse model of a device-related infection by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Animals; Anti-Bacterial Agents; Catheters, Indwelling; Chromatography, High Pressure Liquid; Disease Models, Animal; Levofloxacin; Mice; Mice, Inbred BALB C; Ofloxacin; Rifampin; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Staphylococcus aureus | 2008 |
Comparing the protective effects of ciprofloxacin, moxifloxacin and levofloxacin in mice with lipopolysaccharide-induced acute lung injuries.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Cytokines; Disease Models, Animal; Fluoroquinolones; Levofloxacin; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Quinolines; Respiratory Distress Syndrome | 2008 |
Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Randomized Controlled Trials as Topic; Retrospective Studies; Rhinitis; Sinusitis; Treatment Outcome | 2007 |
Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Endophthalmitis; Female; Levofloxacin; Male; Microbial Sensitivity Tests; Models, Animal; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcal Infections; Staphylococcus epidermidis; Treatment Outcome; Vancomycin; Vitreous Body | 2008 |
Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis.
Topics: Animals; Anti-Inflammatory Agents; Aza Compounds; Cells, Cultured; Conjunctivitis; Endotoxins; Fluoroquinolones; Gatifloxacin; Immunologic Factors; Keratitis; Levofloxacin; Lipopolysaccharides; Macrophages, Peritoneal; Male; Methicillin Resistance; Mice; Mice, Inbred C3H; Moxifloxacin; Ofloxacin; Quinolines; Rabbits; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Tumor Necrosis Factor-alpha | 2008 |
Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague.
Topics: Animals; Anti-Bacterial Agents; Cytokines; Disease Models, Animal; Female; Levofloxacin; Lipoproteins; Macrophages; Mice; Mice, Inbred BALB C; Mutation; Ofloxacin; Plague; Virulence; Virulence Factors; Yersinia pestis; Yersinia pseudotuberculosis | 2008 |
Levofloxacin vs. azithromycin pharmacodynamic activity against S. pneumoniae and H. influenzae with decreased susceptibility to amoxicillin/clavulanic acid.
Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Clavulanic Acid; Computer Simulation; Drug Resistance, Bacterial; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae | 2007 |
Penetration of moxifloxacin and levofloxacin into cancellous and cortical bone in patients undergoing total hip arthroplasty.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Aza Compounds; Bone and Bones; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Injections, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Ofloxacin; Osteomyelitis; Quinolines | 2007 |
Safety of prolonged high-dose levofloxacin therapy for bone infections.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Humans; Levofloxacin; Middle Aged; Muscles; Ofloxacin; Osteomyelitis; Pain; Retrospective Studies; Tendinopathy | 2007 |
[Fluoroquinolone-induced Achilles tendon rupture].
Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Bronchitis; Diabetes Mellitus, Type 1; Female; Humans; Levofloxacin; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Risk Factors; Rupture; Tendinopathy; Tendon Injuries; Ultrasonography | 2008 |
Radiation recall reaction induced by levofloxacin.
Topics: Breast Neoplasms; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Radiodermatitis; Skin; Time Factors | 2008 |
Fluoroquinolones in community-acquired pneumonia when tuberculosis is around: an instructive case.
Topics: Adult; Anti-Bacterial Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Levofloxacin; Male; Mycobacterium tuberculosis; Ofloxacin; Pneumonia, Bacterial; Radiography; Tuberculosis, Pulmonary | 2008 |
Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fatal Outcome; Humans; Levofloxacin; Male; Mutation; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure | 2008 |
Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Escherichia coli; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis | 2008 |
Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis.
Topics: Aged; Anti-Bacterial Agents; Biopsy, Needle; Blood; Carbapenems; Cephalosporins; Drug Resistance, Bacterial; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostate; Prostatitis; Ultrasound, High-Intensity Focused, Transrectal; Urinary Tract Infections; Urine | 2008 |
Emergence of fluoroquinolone resistance in group B streptococcal isolates in Taiwan.
Topics: Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Streptococcus agalactiae; Taiwan | 2008 |
In vitro susceptibilities of bacterial isolates from conjunctival flora to gatifloxacin, levofloxacin, tosufloxacin, and moxifloxacin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aza Compounds; Bacteria; Child; Conjunctiva; Drug Resistance, Microbial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines | 2008 |
Treatment failure rates and health care utilization and costs among patients with community-acquired pneumonia treated with levofloxacin or macrolides in an outpatient setting: a retrospective claims database analysis.
Topics: Adult; Aged; Ambulatory Care; Anti-Bacterial Agents; Community-Acquired Infections; Cost-Benefit Analysis; Databases as Topic; Drug Costs; Drug Utilization; Emergency Service, Hospital; Female; Health Care Costs; Health Resources; Hospital Costs; Humans; Insurance Claim Reporting; Levofloxacin; Logistic Models; Macrolides; Male; Managed Care Programs; Middle Aged; Odds Ratio; Ofloxacin; Pneumonia, Bacterial; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Failure | 2008 |
Antimicrobial susceptibility profile of contemporary clinical strains of Stenotrophomonas maltophilia isolates: can moxifloxacin activity be predicted by levofloxacin MIC results?
Topics: Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Predictive Value of Tests; Quinolines; Stenotrophomonas maltophilia | 2008 |
A pharmacodynamic simulation to assess tigecycline efficacy for hospital-acquired pneumonia compared with other common intravenous antibiotics.
Topics: Anti-Bacterial Agents; Cross Infection; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Models, Biological; Monte Carlo Method; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Tigecycline | 2008 |
Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study.
Topics: Adolescent; Anti-Bacterial Agents; Antitubercular Agents; Child; Child, Preschool; Cross Infection; Cross-Sectional Studies; Drug Resistance, Bacterial; Female; Humans; Infant; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Population Surveillance; Rifampin; Risk Factors; South Africa; Statistics, Nonparametric; Streptococcus pneumoniae; Tuberculosis, Multidrug-Resistant; World Health Organization | 2008 |
Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al.
Topics: Anti-Bacterial Agents; Bacterial Infections; Humans; Levofloxacin; Maxillary Sinusitis; Ofloxacin | 2008 |
Recall urticaria related to levofloxacin.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Ofloxacin; Respiratory Tract Infections; Urticaria | 2008 |
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira.
Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Egypt; Hawaii; Humans; Leptospira; Leptospirosis; Levofloxacin; Microbial Sensitivity Tests; Nicaragua; Ofloxacin; Tetracycline; Thailand | 2008 |
[Case of pneumothorax associated with pulmonary Mycobacterium fortuitum infection].
Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Combined Modality Therapy; Drainage; Drug Resistance, Bacterial; Humans; Levofloxacin; Male; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Pneumonectomy; Pneumothorax; Recurrence; Treatment Outcome; Tuberculosis, Pulmonary | 2008 |
A comparison of levofloxacin and moxifloxacin use in hospitalized community-acquired pneumonia (CAP) patients in the US: focus on length of stay.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Community-Acquired Infections; Comorbidity; Female; Fluoroquinolones; Health Care Costs; Hospitalization; Humans; Infusions, Intravenous; Insurance Claim Review; Length of Stay; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Quinolines; Research Design; Retrospective Studies; Treatment Outcome; United States | 2008 |
Treatment of pulmonary actinomycosis with levofloxacin.
Topics: Actinomycosis; Anti-Bacterial Agents; Diagnosis, Differential; Female; Humans; Levofloxacin; Lung Diseases; Lung Neoplasms; Middle Aged; Ofloxacin; Tomography, X-Ray Computed | 2008 |
Quadruple rescue therapy for Helicobacter pylori infection after two treatment failures.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cytochrome P-450 CYP2C19; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Organometallic Compounds; Patient Selection; Polymorphism, Genetic; Prospective Studies; Rabeprazole; Salvage Therapy; Treatment Outcome | 2008 |
Hypoglycemia and levofloxacin: a case report.
Topics: Aged, 80 and over; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemia; Levofloxacin; Ofloxacin; Respiratory Tract Infections | 2008 |
Levofloxacin and hypoglycemia.
Topics: Clinical Competence; Fluoroquinolones; Gatifloxacin; Health Services Research; Hospitals, University; Humans; Hypoglycemia; Levofloxacin; Ofloxacin; Surveys and Questionnaires | 2008 |
Mutations in the quinolone resistance determining region in Staphylococcus epidermidis recovered from conjunctiva and their association with susceptibility to various fluoroquinolones.
Topics: Aza Compounds; Conjunctiva; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, MDR; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Staphylococcus epidermidis | 2008 |
Effects of fluoroquinolones on bacterial adhesion and on preformed biofilm of strains isolated from urinary double J stents.
Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Biofilms; Dose-Response Relationship, Drug; Enterococcus; Escherichia coli; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones; Staphylococcus; Stenotrophomonas maltophilia; Stents; Ureteral Calculi | 2008 |
Chryseobacterium meningosepticum infection: antibiotic susceptibility and risk factors for mortality.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Chryseobacterium; Ciprofloxacin; Female; Flavobacteriaceae Infections; Humans; Infant; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Retrospective Studies; Risk Factors; Taiwan; Treatment Outcome | 2008 |
Further evidence of a clinically significant levofloxacin-warfarin interaction.
Topics: Anti-Bacterial Agents; Anticoagulants; Drug Interactions; Hemorrhage; Humans; International Normalized Ratio; Levofloxacin; Ofloxacin; Risk Factors; Warfarin | 2008 |
The impact of perioperative atelectasis on antibiotic penetration into lung tissue: an in vivo microdialysis study.
Topics: Adult; Aged; Anti-Bacterial Agents; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Humans; Infusions, Intravenous; Intensive Care Units; Levofloxacin; Microdialysis; Middle Aged; Ofloxacin; Pneumonia; Postoperative Care; Pulmonary Atelectasis | 2008 |
Postantibiotic effects and bactericidal activities of levofloxacin and gatifloxacin at concentrations simulating those of topical ophthalmic administration against fluoroquinolone-resistant and fluoroquinolone-sensitive methicillin-resistant Staphylococcu
Topics: Administration, Topical; Anti-Bacterial Agents; Drug Administration Routes; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Staphylococcus aureus | 2008 |
Quantitative assessment of combination antimicrobial therapy against multidrug-resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Antagonism; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2008 |
[Levofloxacin in the treatment of nosocomial infection in critically ill patients].
Topics: Anti-Bacterial Agents; Critical Illness; Cross Infection; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies | 2008 |
Pharmacokinetics of levofloxacin after single and multiple oral doses in patients undergoing intermittent haemodialysis.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Half-Life; Humans; Kidney Failure, Chronic; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Renal Dialysis; Time Factors | 2008 |
Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes.
Topics: Anti-Bacterial Agents; Aza Compounds; Cell Line, Tumor; Colony Count, Microbial; Cytoplasm; Fluoroquinolones; Humans; Levofloxacin; Listeria monocytogenes; Microbial Viability; Monocytes; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2008 |
Activity of ciprofloxacin and levofloxacin in experimental pneumonia caused by Klebsiella pneumoniae deficient in porins, expressing active efflux and producing QnrA1.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Female; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Bacterial; Porins | 2008 |
Levofloxacin plus rifampicin conservative treatment of 25 early staphylococcal infections of osteosynthetic devices for rigid internal fixation.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Coagulase; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Orthopedic Fixation Devices; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2008 |
Lung microdialysis study of levofloxacin in rats following intravenous infusion at steady state.
Topics: Animals; Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Infusions, Intravenous; Levofloxacin; Lung; Male; Microdialysis; Muscle, Skeletal; Ofloxacin; Rats; Rats, Sprague-Dawley | 2008 |
[A case of phlegmonous gastritis which resolved with medical treatment].
Topics: Aged; Anti-Bacterial Agents; Cellulitis; Drug Therapy, Combination; Female; Gastritis; Humans; Levofloxacin; Male; Ofloxacin; Vancomycin | 2008 |
Determination of levofloxacin and norfloxacin by capillary electrophoresis with electrochemiluminescence detection and applications in human urine.
Topics: Electrophoresis, Capillary; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Levofloxacin; Luminescent Measurements; Male; Norfloxacin; Ofloxacin; Osmolar Concentration; Sodium Hydroxide; Solvents | 2008 |
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia.
Topics: Anti-Bacterial Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hypoglycemia; Kidney Neoplasms; Levofloxacin; Liposarcoma; Male; Middle Aged; Myelinolysis, Central Pontine; Ofloxacin; Peritonitis; Postoperative Complications; Quadriplegia | 2008 |
Intracranial hypertension and levofloxacin: a case report.
Topics: Adolescent; Anti-Bacterial Agents; Diplopia; Headache; Humans; Intracranial Hypertension; Levofloxacin; Male; Ofloxacin; Orbital Fractures | 2009 |
Development and validation of a HPLC method for simultaneous quantitation of gatifloxacin, sparfloxacin and moxifloxacin using levofloxacin as internal standard in human plasma: application to a clinical pharmacokinetic study.
Topics: Administration, Oral; Analytic Sample Preparation Methods; Aza Compounds; Chromatography, High Pressure Liquid; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Reference Standards; Sensitivity and Specificity | 2008 |
Antagonistic effect of rifampin on the efficacy of high-dose levofloxacin in staphylococcal experimental foreign-body infection.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Interactions; Foreign Bodies; Levofloxacin; Male; Ofloxacin; Prosthesis-Related Infections; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 2008 |
[A rare cause of catheter-related bacteremia: Rhizobium radiobacter].
Topics: Adult; Agrobacterium tumefaciens; Anti-Bacterial Agents; Bacteremia; Bone Neoplasms; Catheterization, Central Venous; Catheters, Indwelling; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Osteosarcoma | 2008 |
Comparison of the effect of intracameral moxifloxacin, levofloxacin and cefazolin on rabbit corneal endothelial cells.
Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Aza Compounds; Cefazolin; Cell Count; Cornea; Endothelium, Corneal; Fluoroquinolones; Injections; Levofloxacin; Microscopy, Electron, Scanning; Moxifloxacin; Ofloxacin; Quinolines; Rabbits | 2008 |
Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; Chi-Square Distribution; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Levofloxacin; Meningococcal Vaccines; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumococcal Vaccines; Regression Analysis; Serotyping; Streptococcus pneumoniae; United States | 2008 |
Effects of exposure of Clostridium difficile PCR ribotypes 027 and 001 to fluoroquinolones in a human gut model.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clostridioides difficile; Colony Count, Microbial; Cytotoxins; DNA Gyrase; Feces; Fluoroquinolones; Gastrointestinal Tract; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Ribotyping | 2009 |
Urinary bactericidal activity of single doses (250, 500, 750 and 1000 mg) of levofloxacin against fluoroquinolone-resistant strains of Escherichia coli.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Young Adult | 2008 |
Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Cell Survival; Ciprofloxacin; Conjunctiva; Drug Evaluation, Preclinical; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tetrazolium Salts; Thiazoles | 2008 |
Failure of first-line eradication treatment significantly increases prevalence of antimicrobial-resistant Helicobacter pylori clinical isolates.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Case-Control Studies; Chi-Square Distribution; Clarithromycin; Colony Count, Microbial; Drug Resistance, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Tetracycline Resistance; Treatment Failure | 2008 |
[Analysis on susceptibility of ocular bacterial pathogens to four kinds of fluoroquinolone].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Eye; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2008 |
Coadministration of oral levofloxacin with agents that impair absorption: impact on antibiotic resistance.
Topics: Absorption; Administration, Oral; Anti-Bacterial Agents; Cations; Cations, Divalent; Drug Interactions; Drug Resistance, Bacterial; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Risk Factors | 2008 |
Prevalence and risk factor analysis of trimethoprim-sulfamethoxazole- and fluoroquinolone-resistant Escherichia coli infection among emergency department patients with pyelonephritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance, Bacterial; Emergencies; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pyelonephritis; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination; United States | 2008 |
NIR spectroscopic investigation of two fluoroquinolones, levofloxacin and ofloxacin, and their tablets for qualitative identification of commercial products on the market.
Topics: Anti-Bacterial Agents; Levofloxacin; Ofloxacin; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Tablets | 2008 |
Emergence of fluoroquinolone resistance in outpatient urinary Escherichia coli isolates.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Levofloxacin; Middle Aged; Ofloxacin; Urinary Tract Infections | 2008 |
Mechanisms accounting for fluoroquinolone resistance in Escherichia coli clinical isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Norfloxacin; Ofloxacin | 2009 |
Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.
Topics: Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; United States | 2009 |
Sepsis caused by Elizabethkingia miricola successfully treated with tigecycline and levofloxacin.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Lymphoma, Mantle-Cell; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Sepsis; Stem Cell Transplantation; Tigecycline | 2008 |
[Investigation of interaction between levofloxacin and bovine serum albumin by fluorescence analysis based on liquid drop].
Topics: Fluorescence; Levofloxacin; Ofloxacin; Protein Binding; Serum Albumin, Bovine; Thermodynamics | 2008 |
Preventive effect against post-cataract endophthalmitis: drug delivery intraocular lens versus intracameral antibiotics.
Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Colony Count, Microbial; Drug Delivery Systems; Endophthalmitis; Enterococcus faecalis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Lens Implantation, Intraocular; Lenses, Intraocular; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Postoperative Complications; Rabbits | 2008 |
Distribution of emm type and antibiotic susceptibility of group A streptococci causing invasive and noninvasive disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Carrier Proteins; Child; Child, Preschool; Humans; Infant; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Mutation; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes | 2008 |
Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody.
Topics: Administration, Intranasal; Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Formation; Colony Count, Microbial; Enzyme-Linked Immunosorbent Assay; Female; Francisella tularensis; Levofloxacin; Mice; Mice, Inbred BALB C; Ofloxacin; Survival Analysis; Tularemia; Virulence; Zoonoses | 2008 |
Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury.
Topics: Analysis of Variance; Animals; Chemical and Drug Induced Liver Injury; Female; Fluoroquinolones; Gene Expression; Hepatocytes; Inflammation; Interferon-gamma; Interleukin-18; Janus Kinases; Levofloxacin; Lipopolysaccharides; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Naphthyridines; Necrosis; Ofloxacin; Oligonucleotide Array Sequence Analysis; STAT Transcription Factors; Transcriptional Activation | 2009 |
Decline in the prevalence of pandemic clones Spain23F-1 and Spain9V-3 among US fluoroquinolone-resistant Streptococcus pneumoniae TRUST Surveillance isolates since 2001.
Topics: Clone Cells; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prevalence; Streptococcus pneumoniae; United States | 2008 |
Pharmacodynamics of levofloxacin against characterized ciprofloxacin-resistant Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States | 2008 |
[Prevention of peri-operative infection with levofloxacin in female patients undergoing surgery for stress urinary incontinence].
Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Levofloxacin; Middle Aged; Ofloxacin; Tablets; Treatment Outcome; Urinary Incontinence, Stress; Urinary Tract Infections | 2008 |
Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations.
Topics: Adult; Anti-Bacterial Agents; Asthma; Conjunctivitis; Humans; Immunoglobulin G; Immunoglobulin M; Levofloxacin; Lung; Male; Mucositis; Mycoplasma Infections; Mycoplasma pneumoniae; Ofloxacin; Prednisolone; Radiography, Thoracic; Skin Ulcer | 2008 |
The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.
Topics: Biological Transport; Caco-2 Cells; Cell Compartmentation; Dipeptides; Fluoroquinolones; Humans; Intestinal Absorption; Levofloxacin; Membrane Transport Proteins; Ofloxacin; Peptide Transporter 1; Symporters | 2008 |
[Levofloxacin and macrolides in chronic bronchitis exacerbation: comparative analysis of the treatment efficacy and nonrelapsing periods].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Bronchitis, Chronic; Clarithromycin; Female; Humans; Levofloxacin; Macrolides; Male; Middle Aged; Ofloxacin; Treatment Outcome; Young Adult | 2007 |
Characterization of the pharmacokinetic disposition of levofloxacin in stallions after intravenous and intramuscular administration.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Half-Life; Horses; Injections, Intramuscular; Injections, Intravenous; Levofloxacin; Male; Metabolic Clearance Rate; Ofloxacin; Protein Binding | 2008 |
Activity of levofloxacin alone and in combination with a DnaK inhibitor against gram-negative rods, including levofloxacin-resistant strains.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Colony Count, Microbial; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli Proteins; Gram-Negative Bacteria; HSP70 Heat-Shock Proteins; Insect Proteins; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2009 |
[Large kidney due to levofloxacin].
Topics: Aged; Anti-Infective Agents, Urinary; Humans; Kidney; Levofloxacin; Male; Nephritis, Interstitial; Ofloxacin | 2008 |
Levofloxacin, Amoxicillin, and Omeprazole as first-line triple therapy for Helicobacter pylori eradication.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Therapy, Combination; Female; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Patient Compliance; Treatment Outcome | 2009 |
Disturbance of cellular glucose transport by two prevalently used fluoroquinolone antibiotics ciprofloxacin and levofloxacin involves glucose transporter type 1.
Topics: Anti-Bacterial Agents; Biological Transport; Cell Line, Tumor; Ciprofloxacin; Glucose; Glucose Transporter Type 1; Humans; Levofloxacin; Ofloxacin; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.
Topics: Animals; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Aza Compounds; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Fluoroquinolones; Gatifloxacin; Humans; Isoenzymes; Levofloxacin; Microsomes, Liver; Molecular Structure; Moxifloxacin; Ofloxacin; Quinolines; Reproducibility of Results | 2008 |
Monitoring of Mycoplasma genitalium growth and evaluation of antibacterial activity of antibiotics tetracycline and levofloxacin using a wireless magnetoelastic sensor.
Topics: Anti-Bacterial Agents; Biosensing Techniques; Cell Proliferation; Colony Count, Microbial; Drug Evaluation, Preclinical; Elastic Modulus; Equipment Design; Equipment Failure Analysis; Levofloxacin; Magnetics; Mycoplasma genitalium; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Telemetry; Tetracycline | 2009 |
Sequential determination of norfloxaxin and levofloxacin in the presence of other fluorquinolones using synchronous scanning room-temperature phosphorimetry and Th (IV) as the selective signal inducer.
Topics: Animals; Anti-Infective Agents, Urinary; Humans; Levofloxacin; Luminescent Measurements; Norfloxacin; Ofloxacin; Thallium | 2009 |
A new twist on an old problem: a case of pediatric meningitis caused by multidrug-resistant Streptococcus pneumoniae serotype 19A.
Topics: Anti-Bacterial Agents; Cefuroxime; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Infant; Levofloxacin; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae; Vancomycin | 2008 |
Retrospective assessment of potential interaction between levofloxacin and warfarin.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticoagulants; Biomarkers; Drug Interactions; Female; Humans; Inpatients; International Normalized Ratio; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Time Factors; Warfarin | 2009 |
Pathotype and susceptibility profile of a community-acquired methicillin-resistant Staphylococcus aureus strain responsible for a case of severe pneumonia.
Topics: Adult; Bacterial Proteins; Bacterial Toxins; Community-Acquired Infections; DNA Primers; Exotoxins; Humans; Italy; Leukocidins; Levofloxacin; Male; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Staphylococcal; Polymerase Chain Reaction; Serotyping | 2009 |
Effect of differences in MIC values on clinical outcomes in patients with bloodstream infections caused by gram-negative organisms treated with levofloxacin.
Topics: Adult; Aged; Anti-Bacterial Agents; Cohort Studies; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Length of Stay; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Retrospective Studies; Treatment Outcome | 2009 |
Simultaneous quantification of linezolid, rifampicin, levofloxacin, and moxifloxacin in human plasma using high-performance liquid chromatography with UV.
Topics: Acetamides; Anti-Bacterial Agents; Antibiotics, Antitubercular; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Moxifloxacin; Ofloxacin; Oxazolidinones; Quality Control; Quinolines; Reference Standards; Reproducibility of Results; Rifampin; Solutions; Solvents; Spectrophotometry, Ultraviolet | 2009 |
The resistance patterns of normal ocular bacterial flora to 4 fluoroquinolone antibiotics.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Bacteria, Aerobic; Ciprofloxacin; Conjunctiva; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2009 |
Treatment of pyogenic (non-tuberculous) spondylodiscitis with tailored high-dose levofloxacin plus rifampicin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Discitis; Drug Monitoring; Female; Follow-Up Studies; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Rifampin; Treatment Outcome; Young Adult | 2009 |
Comparative pharmacodynamic interaction analysis between ciprofloxacin, moxifloxacin and levofloxacin and antifungal agents against Candida albicans and Aspergillus fumigatus.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus fumigatus; Aza Compounds; Candida albicans; Ciprofloxacin; Drug Antagonism; Drug Synergism; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines | 2009 |
[Levofloxacin susceptibility of Mycobacterium tuberculosis].
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Drug Resistance, Multiple, Bacterial; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin | 2005 |
Comparative mutant prevention concentration and mutant selection window of sitafloxacin versus other quinolones using strains of Haemophilus influenzae with decreasing susceptibility to levofloxacin.
Topics: Adaptation, Biological; Anti-Bacterial Agents; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Mutation; Ofloxacin; Quinolones; Selection, Genetic | 2009 |
Pharmacokinetics, urinary excretion and milk penetration of levofloxacin in lactating goats.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Female; Goats; Injections, Intramuscular; Injections, Intravenous; Lactation; Levofloxacin; Milk; Ofloxacin; Random Allocation; Species Specificity; Urinalysis | 2009 |
Levofloxacin-induced delirium.
Topics: Age Factors; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Brain; Clarithromycin; Confusion; Delirium; Ertapenem; Hallucinations; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia; Risk Factors; Sex Factors; Time Factors; Withholding Treatment | 2009 |
High doses of levofloxacin vs moxifloxacin against staphylococcal experimental foreign-body infection: the effect of higher MIC-related pharmacokinetic parameters on efficacy.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Foreign Bodies; Levofloxacin; Male; Microbial Sensitivity Tests; Microbial Viability; Models, Animal; Moxifloxacin; Ofloxacin; Quinolines; Rats; Rats, Wistar; Staphylococcal Infections; Time Factors | 2009 |
Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Resistance, Bacterial; Hong Kong; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal; Prevalence; Streptococcus pneumoniae; Young Adult | 2009 |
Rapid and sensitive spectrofluorimetric determination of enrofloxacin, levofloxacin and ofloxacin with 2,3,5,6-tetrachloro-p-benzoquinone.
Topics: Anti-Bacterial Agents; Chloranil; Enrofloxacin; Fluoroquinolones; Fungicides, Industrial; Levofloxacin; Molecular Structure; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2009 |
Medical resource utilization among community-acquired pneumonia patients initially treated with levofloxacin 750 mg daily versus ceftriaxone 1000 mg plus azithromycin 500 mg daily: a US-based study.
Topics: Adult; Aged; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Community-Acquired Infections; Drug Therapy, Combination; Female; Health Resources; Humans; Least-Squares Analysis; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Practice Guidelines as Topic; Societies, Medical; United States | 2009 |
Antimicrobial susceptibility of Streptococcus pyogenes in Central, Eastern, and Baltic European Countries, 2005 to 2006: the cefditoren surveillance program.
Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Child; Drug Resistance, Bacterial; Europe; Female; Humans; Levofloxacin; Macrolides; Male; Microbial Sensitivity Tests; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes; Young Adult | 2009 |
Fluoroquinolone-resistant Brucella melitensis mutants obtained in vitro.
Topics: Anti-Bacterial Agents; Aza Compounds; Brucella melitensis; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Norfloxacin; Ofloxacin; Quinolines; Sequence Analysis, DNA | 2009 |
Susceptibility comparisons of normal preoperative conjunctival bacteria to fluoroquinolones.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Bacteria; Conjunctiva; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Ofloxacin; Preoperative Care; Quinolines | 2009 |
Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Carrier State; Child; Child, Preschool; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Mutation, Missense; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; South Africa; Streptococcus pneumoniae; Tuberculosis | 2009 |
Targeted delivery of levofloxacin-liposomes for the treatment of pulmonary inflammation.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Chemistry, Pharmaceutical; Female; Levofloxacin; Liposomes; Mice; Ofloxacin; Pneumonia; Rabbits; Solubility; Tissue Distribution | 2009 |
Levofloxacin-induced hypoglycemia: a rare but life-threatening side effect of a widely used antibiotic.
Topics: Aged; Anti-Bacterial Agents; Female; Humans; Hypoglycemia; Levofloxacin; Ofloxacin | 2009 |
Bactericidal activity of the combination of levofloxacin with rifampin in experimental prosthetic knee infection in rabbits due to methicillin-susceptible Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Humans; Knee Prosthesis; Levofloxacin; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Prosthesis-Related Infections; Rabbits; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2009 |
[Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents].
Topics: Adolescent; Amoxicillin; Anti-Infective Agents; Child; Clarithromycin; Drug Resistance, Bacterial; Female; Gastroscopy; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Ofloxacin | 2009 |
Seven-day PPI-triple therapy with levofloxacin is very effective for Helicobacter pylori eradication.
Topics: Amoxicillin; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors | 2009 |
[Resistant mutant prevention concentration of fluoroquinolones in clinical isolates of extended spectrum beta-lactamase (ESBL) producing and non-producing strains of Escherichia coli].
Topics: Anti-Infective Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin | 2009 |
Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia.
Topics: Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Blood; Cefotaxime; Community-Acquired Infections; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Oxacillin; Pneumococcal Infections; Serotyping; Spain; Sputum; Streptococcus pneumoniae | 2009 |
Levofloxacin-induced catatonia.
Topics: Anti-Infective Agents, Urinary; Catatonia; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin | 2009 |
Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections.
Topics: Adolescent; Adult; Aged; Bacterial Capsules; Child; Child, Preschool; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Polymerase Chain Reaction; Streptococcus agalactiae | 2009 |
Loss of erythromycin resistance genes from strains of Streptococcus pyogenes that have developed resistance to levofloxacin.
Topics: Anti-Bacterial Agents; Conjugation, Genetic; Drug Resistance, Bacterial; Erythromycin; Gene Deletion; Gene Transfer, Horizontal; Genes, Bacterial; Genotype; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pyogenes | 2009 |
Mechanism-based inhibition of CYP1A2 by antofloxacin, an 8-NH2 derivative of levofloxacin in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Kinetics; Levofloxacin; Male; Microsomes, Liver; Models, Biological; Ofloxacin; Phenacetin; Rats; Rats, Sprague-Dawley | 2009 |
Activity of levofloxacin and ciprofloxacin on biofilms and planktonic cells of Stenotrophomonas maltophilia isolates from patients with device-associated infections.
Topics: Anti-Infective Agents; Argentina; Biofilms; Ciprofloxacin; Cross Infection; Drug Resistance, Multiple, Bacterial; Equipment Contamination; Gram-Negative Bacterial Infections; Hospitals, University; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Stenotrophomonas maltophilia | 2009 |
[Epidemiological study of levofloxacin-resistant Streptococcus pneumoniae isolated from 2003 through 2006 in Japan].
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Epidemiologic Methods; Humans; Japan; Levofloxacin; Middle Aged; Ofloxacin; Pneumococcal Infections; Software; Streptococcus pneumoniae | 2009 |
Pharmacodynamics of levofloxacin in a murine pneumonia model of Pseudomonas aeruginosa infection: determination of epithelial lining fluid targets.
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelium; Female; Levofloxacin; Mice; Ofloxacin; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections | 2009 |
Molecular analysis of the gyrA and gyrB quinolone resistance-determining regions of fluoroquinolone-resistant Clostridium difficile mutants selected in vitro.
Topics: Aza Compounds; Clostridioides difficile; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines | 2009 |
Subinhibitory fluoroquinolone exposure selects for reduced beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus and alterations in the SOS-mediated response.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Ciprofloxacin; Community-Acquired Infections; DNA Gyrase; DNA Mutational Analysis; DNA Transposable Elements; Fluoroquinolones; Gene Expression Profiling; Humans; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nafcillin; Ofloxacin; Penicillin-Binding Proteins; Selection, Genetic; SOS Response, Genetics; Staphylococcal Infections; Transcription Factors; Up-Regulation | 2009 |
[Acute pancreatitis associated with levofloxacin].
Topics: Acute Disease; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pancreatitis | 2009 |
Sitafloxacin activity against Helicobacter pylori isolates, including those with gyrA mutations.
Topics: Anti-Bacterial Agents; DNA Gyrase; Fluoroquinolones; Helicobacter pylori; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin | 2009 |
Bilateral acanthamoeba keratitis after orthokeratology.
Topics: Acanthamoeba Keratitis; Biguanides; Contact Lenses, Extended-Wear; Drug Therapy, Combination; Female; Functional Laterality; Humans; Levofloxacin; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult | 2009 |
Levofloxacin ozonation in water: rate determining process parameters and reaction pathway elucidation.
Topics: Environmental Pollutants; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Models, Chemical; Models, Molecular; Molecular Conformation; Ofloxacin; Ozone; Quantum Theory; tert-Butyl Alcohol; Water | 2009 |
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercular Agents; Aspartate Aminotransferases; Aza Compounds; Ethambutol; Female; Fluoroquinolones; Hepatic Insufficiency; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Streptomycin; Treatment Outcome; Tuberculosis; Young Adult | 2009 |
An atypical case of microcysts associated with silicone hydrogel contact lens: findings on in vivo confocal laser microscopy.
Topics: Adult; Betamethasone; Contact Lenses, Hydrophilic; Corneal Diseases; Cysts; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Levofloxacin; Microscopy, Confocal; Ofloxacin; Ophthalmic Solutions; Silicones; Treatment Outcome; Visual Acuity | 2009 |
Microbiological appraisal of levofloxacin activity against Pseudomonas aeruginosa biofilm in combination with different calcium chanel blockers in vitro.
Topics: Anti-Bacterial Agents; Biofilms; Calcium Channel Blockers; Drug Therapy, Combination; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2009 |
A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Cefepime; Cefotaxime; Cephalosporins; Drug Resistance, Bacterial; Enterococcus; Escherichia coli Infections; Female; Humans; Infusions, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Leukocyte Count; Levofloxacin; Liver Cirrhosis; Male; Microbial Sensitivity Tests; Middle Aged; Neutrophils; Ofloxacin; Peritonitis; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections | 2010 |
Comparison of the in vitro and in vivo susceptibilities of Burkholderia mallei to Ceftazidime and Levofloxacin.
Topics: Animals; Anti-Bacterial Agents; Burkholderia mallei; Ceftazidime; Cell Line; Drug Resistance, Bacterial; Female; Glanders; Levofloxacin; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Ofloxacin | 2009 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures | 2009 |
Inhibitory effects on bacterial growth and beta-ketoacyl-ACP reductase by different species of maple leaf extracts and tannic acid.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Acer; Alcohol Oxidoreductases; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Fatty Acids; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Plant Extracts; Plant Leaves; Tannins | 2010 |
Hypoglycemia associated with the use of levofloxacin.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Diabetes Mellitus, Type 2; Drug Interactions; Glipizide; Humans; Hypoglycemia; Hypoglycemic Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia | 2009 |
Evaluation of the mutant selection window for fluoroquinolones against Neisseria gonorrhoeae.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Neisseria gonorrhoeae; Ofloxacin; Quinolines; Selection, Genetic | 2009 |
Resistance to metronidazole, clarithromycin and levofloxacin of Helicobacter pylori before and after clarithromycin-based therapy in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Asian People; Child; Clarithromycin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Patient Selection; Prevalence; Taiwan; Time Factors; Treatment Failure; Young Adult | 2009 |
Toxic epidermal necrolysis induced by levofloxacin.
Topics: Fatal Outcome; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pyelonephritis; Stevens-Johnson Syndrome | 2009 |
Levofloxacin versus tetracycline antibiotics for the treatment of scrub typhus.
Topics: Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Scrub Typhus; Taiwan; Tetracycline; Treatment Outcome | 2010 |
In vitro bactericidal activity of the N-terminal fragment of the frog peptide esculentin-1b (Esc 1-18) in combination with conventional antibiotics against Stenotrophomonas maltophilia.
Topics: Amikacin; Amphibian Proteins; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Ceftazidime; Colistin; Drug Synergism; Humans; Kinetics; Levofloxacin; Microbial Viability; Ofloxacin; Peptide Fragments; Rana esculenta; Serum; Stenotrophomonas maltophilia | 2009 |
[Voice on the treatment of ureaplasmas infections].
Topics: Anti-Infective Agents; Azithromycin; Dose-Response Relationship, Drug; Doxycycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Ureaplasma; Ureaplasma Infections; Ureaplasma urealyticum | 2009 |
Efficacy of aerosol MP-376, a levofloxacin inhalation solution, in models of mouse lung infection due to Pseudomonas aeruginosa.
Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Aztreonam; Disease Models, Animal; Female; Levofloxacin; Lung Diseases; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2009 |
Levofloxacin and glycaemic disorders. Diabetic patients: beware.
Topics: Canada; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Ofloxacin | 2008 |
Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Doxycycline; Fatal Outcome; Hepatitis; Humans; Levofloxacin; Liver Failure, Acute; Male; Middle Aged; Naproxen; Ofloxacin; Pericarditis; Pneumonia, Mycoplasma | 2009 |
Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis.
Topics: Aged; Aged, 80 and over; Drug Resistance, Bacterial; Echocardiography; Endocarditis, Subacute Bacterial; Endophthalmitis; Humans; Levofloxacin; Male; Ofloxacin; Streptococcal Infections; Streptococcus mitis | 2009 |
Quantitative determination of levofloxacin hemihydrate in bulk and tablets by UV-spectrophotometry and first order derivative methods.
Topics: Anti-Bacterial Agents; Calibration; Levofloxacin; Ofloxacin; Quality Control; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets | 2009 |
Activity of amikacin, ertapenem, ciprofloxacin and levofloxacin alone and in combination against resistant nosocomial pathogens by time-kill.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Cross Infection; Drug Synergism; Drug Therapy, Combination; Ertapenem; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2008 |
A biodegradable filament for controlled drug delivery.
Topics: Absorbable Implants; Administration, Topical; Animals; Chemistry, Pharmaceutical; Conjunctiva; Delayed-Action Preparations; Dexamethasone; Dimethyl Sulfoxide; Drug Carriers; Drug Compounding; Lactic Acid; Levofloxacin; Ofloxacin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Solubility; Solvents; Surface Properties; Tears; Tensile Strength; Transition Temperature | 2009 |
Pharmacokinetic studies of levofloxacin after oral administration in healthy and febrile cow calves.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Female; Fever; Levofloxacin; Ofloxacin | 2009 |
[Etiological analysis of ocular non-viral microbial isolates in children and their antibiotics susceptibility in vitro].
Topics: Adolescent; Anti-Infective Agents; Bacteria; Child; Child, Preschool; Drug Resistance, Microbial; Eye Infections; Female; Fluconazole; Humans; Infant; Infant, Newborn; Levofloxacin; Male; Microbial Sensitivity Tests; Mitosporic Fungi; Ofloxacin; Retrospective Studies; Rifampin | 2009 |
Acquired perforating calcific collagenosis after topical calcium chloride exposure.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Betamethasone; Calcinosis; Calcium Chloride; Cicatrix; Collagen Diseases; Drug Therapy, Combination; Elastic Tissue; Humans; Levofloxacin; Male; Neutrophil Infiltration; Ofloxacin; Skin; Skin Diseases; Thigh; Treatment Outcome; Young Adult | 2010 |
Characterization of clinical blood isolates of Streptococcus agalactiae with reduced susceptibility to levofloxacin.
Topics: Agglutination Tests; Anti-Bacterial Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Retrospective Studies; Streptococcal Infections; Streptococcus agalactiae | 2009 |
Carrier-mediated uptake of Levofloxacin by BeWo cells, a human trophoblast cell line.
Topics: Anti-Bacterial Agents; Cell Line, Tumor; Humans; Ion Pumps; Levofloxacin; Ofloxacin; Trophoblasts | 2010 |
Helicobacter pylori first-line treatment and rescue option containing levofloxacin in patients allergic to penicillin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Clarithromycin; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Omeprazole; Penicillins; Prospective Studies; Treatment Outcome | 2010 |
A validated stability-indicating RP-HPLC method for levofloxacin in the presence of degradation products, its process related impurities and identification of oxidative degradant.
Topics: Buffers; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Stability; Hydrolysis; Levofloxacin; Mass Spectrometry; Models, Chemical; Ofloxacin; Oxidative Stress; Oxygen; Reproducibility of Results; Technology, Pharmaceutical | 2009 |
Prophylactic use of isepamicin and levofloxacin for transrectal prostate biopsy: a retrospective single center study.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Drug Therapy, Combination; Gentamicins; Humans; Levofloxacin; Male; Ofloxacin; Prostate; Prostatitis; Rectum; Retrospective Studies; Risk Factors; Ultrasound, High-Intensity Focused, Transrectal | 2009 |
Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Survival; Cells, Cultured; Ciprofloxacin; Electric Impedance; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines | 2010 |
Benzalkonium chloride enhances antibacterial activity of gatifloxacin and reduces its propensity to select for fluoroquinolone-resistant strains.
Topics: Anti-Bacterial Agents; Aza Compounds; Benzalkonium Compounds; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2009 |
Effects of levofloxacin hydrochloride on photosystem II activity and heterogeneity of Synechocystis sp.
Topics: Anti-Bacterial Agents; Chlorophyll; Levofloxacin; Ofloxacin; Photosynthesis; Photosystem II Protein Complex; Synechocystis | 2009 |
Clinical and economic outcomes in respiratory tract infections: The impact of bacterial resistance.
Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Community-Acquired Infections; Doxycycline; Drug Resistance, Multiple, Bacterial; Humans; Kentucky; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Respiratory Tract Infections; Streptococcus pneumoniae; Treatment Outcome; United States | 2002 |
Urinary Mycobacterium szulgai infection in an immunocompetent patient.
Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Immunocompetence; Isoniazid; Levofloxacin; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Rifampin; Urinary Tract Infections | 2009 |
Convulsant activity of sitafloxacin and its interactions with anti-inflammatory drugs in mice.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Interactions; Fluoroquinolones; Injections, Intraventricular; Levofloxacin; Mice; Ofloxacin; Seizures | 2009 |
Levofloxacin-induced severe thrombocytopenia.
Topics: Aged; Anti-Bacterial Agents; Hemoptysis; Humans; Levofloxacin; Male; Ofloxacin; Thrombocytopenia | 2009 |
Compatibility of levofloxacin injection and magnesium sulfate.
Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Drug Incompatibility; Infusions, Parenteral; Levofloxacin; Magnesium Sulfate; Metals; Ofloxacin; Pharmaceutical Solutions | 2009 |
The impact of a change in antibacterial prophylaxis from ceftazidime to levofloxacin in allogeneic hematopoietic cell transplantation.
Topics: Adult; Aged; Antibiotic Prophylaxis; Bacteremia; Ceftazidime; Disease-Free Survival; Drug Resistance, Bacterial; Female; Hematopoietic Stem Cell Transplantation; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Transplantation Conditioning; Young Adult | 2010 |
Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells.
Topics: Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Carnitine; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Levofloxacin; Ofloxacin; Temperature; Time Factors | 2009 |
Multicenter evaluation of Bactec MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Tuberculosis | 2009 |
Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Cloxacillin; Colony Count, Microbial; Cytoplasm; Disease Models, Animal; Foreign Bodies; Levofloxacin; Ofloxacin; Rats; Staphylococcal Infections; Staphylococcus aureus | 2009 |
Evaluation of a new test, genotype HelicoDR, for molecular detection of antibiotic resistance in Helicobacter pylori.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Clarithromycin; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Molecular Diagnostic Techniques; Nucleic Acid Hybridization; Ofloxacin; Point Mutation; Predictive Value of Tests; Sensitivity and Specificity; Sequence Deletion | 2009 |
Bilateral acanthamoeba keratitis after orthokeratology.
Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Biguanides; Drug Therapy, Combination; Escherichia coli Infections; Female; Functional Laterality; Humans; Levofloxacin; Microscopy, Phase-Contrast; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult | 2010 |
Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; Child; Child, Preschool; Community-Acquired Infections; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Polymerase Chain Reaction; Risk Factors; Sequence Analysis, Protein; Serotyping; Streptococcus pneumoniae; Taiwan; Young Adult | 2010 |
[Collagen hydroxyapatite (Healos) saturated with gentamicin or levofloxacin. In vitro antimicrobial effectiveness - a pilot study].
Topics: Anti-Bacterial Agents; Bone Substitutes; Collagen; Dose-Response Relationship, Drug; Durapatite; Escherichia coli; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pilot Projects; Staphylococcus aureus; Streptococcus pyogenes | 2010 |
Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis.
Topics: Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Comorbidity; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Outpatients; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Rhinitis; Sinusitis; Surgical Wound Infection | 2009 |
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis.
Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Cystic Fibrosis; Humans; Levofloxacin; Lung Diseases; Microbial Sensitivity Tests; Ofloxacin; Sputum | 2010 |
Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients.
Topics: Aerobiosis; Aerosols; Anaerobiosis; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Oxygen; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors | 2010 |
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results | 2009 |
Safety of intracameral injection of gatifloxacin, levofloxacin on corneal endothelial structure and viability.
Topics: Animals; Anterior Chamber; Anti-Infective Agents; Cell Survival; Endophthalmitis; Endothelium, Corneal; Female; Fluoroquinolones; Gatifloxacin; Injections; Levofloxacin; Male; Microscopy, Electron, Scanning; Ofloxacin; Rabbits | 2009 |
[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007].
Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Gastrointestinal Diseases; Humans; Japan; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Time Factors; Urinary Tract Infections | 2009 |
Hospital visits and costs following outpatient treatment of CAP with levofloxacin or moxifloxacin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Ambulatory Care; Anti-Infective Agents; Aza Compounds; Community-Acquired Infections; Costs and Cost Analysis; Female; Fluoroquinolones; Hospitalization; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Outpatients; Pneumonia; Quinolines; Young Adult | 2010 |
Post-antibiotic effect of levofloxacin and tobramycin alone or in combination with cefepime against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Time Factors; Tobramycin | 2009 |
Comparative study of the mutant prevention concentrations of moxifloxacin, levofloxacin, and gemifloxacin against pneumococci.
Topics: Anti-Bacterial Agents; Aza Compounds; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Polymerase Chain Reaction; Quinolines; Streptococcus pneumoniae | 2010 |
Microbiological analysis of epidermal growth factor receptor inhibitor therapy-associated paronychia.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cephalosporins; Cetuximab; Ciprofloxacin; ErbB Receptors; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Ofloxacin; Paronychia; Retrospective Studies; Skin | 2010 |
Incidence and epidemiology of levofloxacin resistance in Streptococcus pneumoniae: experience from a tertiary referral hospital in England.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; beta-Lactam Resistance; DNA Fingerprinting; DNA Gyrase; DNA Topoisomerase IV; England; Female; Genotype; Hospitals, Teaching; Humans; Incidence; Infant; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Sequence Analysis, DNA; Serotyping; Streptococcal Infections; Streptococcus pneumoniae; Young Adult | 2010 |
Fluoroquinolone resistance of Pseudomonas aeruginosa isolates causing nosocomial infection is correlated with levofloxacin but not ciprofloxacin use.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Cross Infection; Drug Resistance, Bacterial; Drug Utilization; Fluoroquinolones; Hospitals; Humans; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Taiwan | 2010 |
[Efficacy of levofloxacin, lomefloxacin and moxifloxacin vs. other fluoroquinolones in experimental plague due to FI+ and FI- strains of Yersinia pestis in Albino mice].
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Mice; Moxifloxacin; Ofloxacin; Plague; Quinolines; Species Specificity; Time Factors; Yersinia pestis | 2009 |
[Therapeutic efficacy of levofloxacin against a model of replicable Legionella pneumophila lung infection in DBA/2 mice].
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Bacterial; Female; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Mice; Mice, Inbred DBA; Microbial Sensitivity Tests; Ofloxacin; Treatment Outcome | 2009 |
In vitro killing activity of crevicular concentrations of tinidazole plus common oral antibiotics against high-density mixed inocula of periodontal pathogens in strict anaerobic conditions.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Clavulanic Acid; Clindamycin; Drug Synergism; Drug Therapy, Combination; Gingival Crevicular Fluid; Humans; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Periodontal Diseases; Tinidazole | 2010 |
[The effect of CD4+ CD25+ regulatory T cell inactivation combined with levofloxacin on murine tuberculosis].
Topics: Animals; Anti-Bacterial Agents; Female; Levofloxacin; Mice; Mice, Inbred C57BL; Ofloxacin; T-Lymphocytes, Regulatory; Tuberculosis, Pulmonary | 2009 |
Helicobacter pylori antibiotic resistance and [13C]urea breath test values.
Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; Female; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Statistics as Topic; Urea; Urease | 2010 |
Intensification of sonochemical degradation of antibiotics levofloxacin using carbon tetrachloride.
Topics: Anti-Bacterial Agents; Carbon Tetrachloride; Hydrogen-Ion Concentration; Hydroxyl Radical; Levofloxacin; Ofloxacin; Solutions; tert-Butyl Alcohol; Ultrasonics; Water | 2010 |
Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection.
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cells, Cultured; Colony Count, Microbial; Cytokines; Female; Francisella tularensis; Humans; Immunologic Factors; Levofloxacin; Lung; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Ofloxacin; Poly I-C; Respiratory Tract Infections; Survival Analysis; Toll-Like Receptor 3; Tularemia | 2010 |
Fluoroquinolone resistance in Streptococcus dysgalactiae subsp. equisimilis and evidence for a shared global gene pool with Streptococcus pyogenes.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gene Pool; Humans; Levofloxacin; Molecular Sequence Data; Ofloxacin; Phylogeny; Point Mutation; Streptococcal Infections; Streptococcus; Streptococcus pyogenes | 2010 |
Rapidly fatal bacteremic pneumonia caused by Klebsiella pneumoniae with K1 hypermucoviscosity phenotype in a previously healthy young man receiving levofloxacin treatment.
Topics: Anti-Bacterial Agents; Antigens, Bacterial; Bacteremia; Bacterial Capsules; Bacterial Typing Techniques; Fatal Outcome; Humans; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Multiple Organ Failure; Ofloxacin; Phenotype; Pneumonia, Bacterial; Polysaccharides, Bacterial; Serotyping; Shock, Septic; Young Adult | 2009 |
The effect of human cord blood therapy on the intestinal tract of lethally irradiated mice: possible use for mass casualties.
Topics: Animals; Anti-Bacterial Agents; Cord Blood Stem Cell Transplantation; DNA; Female; Fetal Blood; Gastrointestinal Tract; Humans; Levofloxacin; Mass Casualty Incidents; Mice; Ofloxacin; Survival Rate; Time Factors | 2010 |
Antibiotic resistance of Helicobacter pylori in Israeli children.
Topics: Adolescent; Amoxicillin; Analysis of Variance; Anti-Bacterial Agents; Biopsy; Chi-Square Distribution; Child; Child, Preschool; Clarithromycin; Drug Resistance, Multiple, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Infant; Israel; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Ofloxacin; Prospective Studies; Surveys and Questionnaires; Tetracycline; Treatment Failure | 2010 |
Macrolides versus quinolones in Legionella pneumonia: results from the Community-Acquired Pneumonia Organization international study.
Topics: Administration, Oral; Anti-Bacterial Agents; Azithromycin; Chi-Square Distribution; Clarithromycin; Community-Acquired Infections; Female; Humans; Kaplan-Meier Estimate; Legionella pneumophila; Legionnaires' Disease; Length of Stay; Levofloxacin; Male; Ofloxacin; Retrospective Studies; Time Factors; Treatment Outcome | 2010 |
Microbiological outcome of complicated urinary tract infections treated with levofloxacin: a pharmacokinetic/pharmacodynamic analysis.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Computer Simulation; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Serum; Treatment Outcome; Urinary Tract Infections; Urine | 2010 |
Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Female; Foreign Bodies; Humans; Levofloxacin; Mice; Mice, Inbred BALB C; Ofloxacin; Polymers; Prosthesis-Related Infections; Staphylococcal Infections; Staphylococcus aureus | 2010 |
N-heterocycle construction via cyclic sulfamidates. Applications in synthesis.
Topics: Anti-Bacterial Agents; Bridged-Ring Compounds; Cyclization; Lactams; Levofloxacin; Ofloxacin; Paroxetine; Pyrroles; Sulfonamides | 2010 |
First report of treatment of Anaerobiospirillum succiniciproducens bloodstream infection with levofloxacin.
Topics: Aged, 80 and over; Anaerobiospirillum; Anti-Bacterial Agents; Bacteremia; DNA, Bacterial; DNA, Ribosomal; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microscopy; Microscopy, Electron, Transmission; Ofloxacin; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2010 |
Colonisation of fluoroquinolone-resistant Haemophilus influenzae among nursing home residents in southern Taiwan.
Topics: Aged; Aza Compounds; beta-Lactamases; Colony Count, Microbial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Male; Moxifloxacin; Nursing Homes; Ofloxacin; Prospective Studies; Quinolines; Risk Factors; Serotyping; Taiwan | 2010 |
Spectrometric studies on the sonodynamic damage of protein in the presence of levofloxacin.
Topics: Animals; Cattle; Fluorescence; Hydrogen-Ion Concentration; Hydroxyl Radical; Levofloxacin; Ofloxacin; Osmolar Concentration; Oxidation-Reduction; Reactive Oxygen Species; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis; Superoxides; Temperature; Ultrasonics | 2010 |
Interaction study between levofloxacin and omeprazole using urinary pharmacokinetic data.
Topics: Adolescent; Adult; Drug Interactions; Female; Humans; Levofloxacin; Male; Ofloxacin; Omeprazole; Time Factors | 2010 |
The combination of meropenem and levofloxacin is synergistic with respect to both Pseudomonas aeruginosa kill rate and resistance suppression.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Genes, Bacterial; Humans; In Vitro Techniques; Levofloxacin; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2010 |
In vitro activities of DC-159a, a novel fluoroquinolone, against Mycobacterium species.
Topics: Aminopyridines; Antitubercular Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium; Mycobacterium avium Complex; Mycobacterium chelonae; Mycobacterium fortuitum; Mycobacterium Infections; Mycobacterium kansasii; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Quinolines; Rifampin; Species Specificity | 2010 |
Levofloxacin-induced Achilles tendinitis in a young adult in the absence of predisposing conditions.
Topics: Achilles Tendon; Adult; Anti-Bacterial Agents; Community-Acquired Infections; Disease Susceptibility; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia; Tendinopathy; Young Adult | 2010 |
[Study on the interaction of ofloxacin and levofloxacin with DNA].
Topics: Animals; Cattle; DNA; Fluorescence Polarization; Levofloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2010 |
A new second-line sequential regimen for Helicobacter pylori eradication based on levofloxacin: a pilot study.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pilot Projects; Young Adult | 2010 |
Levofloxacin-induced torsades de pointes.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Coronary Angiography; Diagnosis, Differential; Electrocardiography; Female; Heart Rate; Humans; Levofloxacin; Myocardial Infarction; Ofloxacin; Torsades de Pointes | 2010 |
Antibacterial efficacy of inhalable levofloxacin-loaded polymeric nanoparticles against E. coli biofilm cells: the effect of antibiotic release profile.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Biofilms; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Nanoparticles; Ofloxacin; Time Factors | 2010 |
In vitro selection of resistance in Escherichia coli and Klebsiella spp. at in vivo fluoroquinolone concentrations.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Dioxolanes; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Klebsiella; Klebsiella Infections; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Respiratory Tract Infections; Selection, Genetic; Urinary Tract Infections | 2010 |
Maternal and fetal blood levels of moxifloxacin, levofloxacin, cefepime and cefoperazone.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Cefepime; Cefoperazone; Cephalosporins; Female; Fetal Blood; Fluoroquinolones; Humans; Infant, Newborn; Injections, Intravenous; Levofloxacin; Maternal-Fetal Exchange; Moxifloxacin; Ofloxacin; Pregnancy; Pregnancy Complications, Infectious; Quinolines | 2010 |
[Experience accumulated in hospital setting with levofloxacin, in monotherapy and in association therapy].
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Community-Acquired Infections; Cross Infection; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Hospital Departments; Humans; Levofloxacin; Multicenter Studies as Topic; Neoplasms; Neutropenia; Ofloxacin; Practice Guidelines as Topic; Risk Factors; Treatment Outcome | 2009 |
Effect of levofloxacin and pefloxacin on humoral immune response elicited by bovine serum albumin docked in gelatin microparticles and nanoparticles.
Topics: Animals; Anti-Bacterial Agents; Drug Compounding; Drug Stability; Electrochemistry; Enzyme-Linked Immunosorbent Assay; Excipients; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gelatin; Glutaral; Immunity, Humoral; Immunoglobulin E; Immunologic Factors; Indicators and Reagents; Levofloxacin; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Ofloxacin; Particle Size; Pefloxacin; Rats; Rats, Wistar; Serum Albumin, Bovine | 2010 |
Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Least-Squares Analysis; Levofloxacin; Ofloxacin; Oxazines; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2010 |
Mutation characterization of gyrA and gyrB genes in levofloxacin-resistant Mycobacterium tuberculosis clinical isolates from Guangdong Province in China.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; China; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Mycobacterium tuberculosis; Ofloxacin; Sequence Analysis, DNA; Tuberculosis, Pulmonary; Young Adult | 2010 |
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Corneal Ulcer; Disease Models, Animal; Drug Resistance, Bacterial; Eye Infections, Bacterial; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin; Vancomycin | 2010 |
Clarithromycin or levofloxacin in the sequential therapy for H. pylori eradication?
Topics: Adolescent; Adult; Aged; Clarithromycin; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Tinidazole; Young Adult | 2010 |
In vitro synergistic/additive activity of levofloxacin with meropenem against Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Drug Synergism; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Stenotrophomonas maltophilia; Thienamycins | 2010 |
In vitro and in vivo evaluation of levofloxacin sustained-release capsules.
Topics: Animals; Biological Availability; Capsules; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dogs; Drug Administration Schedule; Drug Implants; Excipients; Levofloxacin; Male; Ofloxacin; Solubility; Technology, Pharmaceutical | 2011 |
A case of Campylobacter jejuni bacteremia in a renal transplant patient.
Topics: Anti-Bacterial Agents; Bacteremia; Campylobacter Infections; Campylobacter jejuni; Diarrhea; Female; Humans; Immunocompromised Host; Kidney Transplantation; Levofloxacin; Middle Aged; Ofloxacin; Treatment Outcome | 2010 |
Antimicrobial susceptibility testing of newer quinolones against gram positive and gram negative clinical isolates.
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2010 |
A province-level risk factor analysis of fluoroquinolone consumption patterns in Canada (2000-06).
Topics: Anti-Bacterial Agents; Canada; Ciprofloxacin; Drug Utilization; Fluoroquinolones; Humans; Influenza, Human; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Risk Factors; Socioeconomic Factors | 2010 |
[Safety of floracid (levofloxacin), a Russian antimicrobial, in the treatment of outpatients].
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Drugs, Generic; Female; Humans; Infections; Levofloxacin; Male; Middle Aged; Moscow; Ofloxacin | 2009 |
Second-line and rescue therapies for Helicobacter pylori eradication in clinical practice.
Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Helicobacter Infections; Helicobacter pylori; Humans; Italy; Levofloxacin; Male; Medication Adherence; Middle Aged; Ofloxacin; Omeprazole; Practice Guidelines as Topic; Proton Pump Inhibitors; Rifabutin; Time Factors; Treatment Failure | 2010 |
Maternal blood and amniotic fluid levels of moxifloxacin, levofloxacin and cefixime.
Topics: Adult; Amniocentesis; Amniotic Fluid; Anti-Bacterial Agents; Aza Compounds; Cefixime; Female; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Pregnancy; Quinolines; Statistics, Nonparametric | 2010 |
Bioavailability and efficacy of levofloxacin against Francisella tularensis in the common marmoset (Callithrix jacchus).
Topics: Animals; Anti-Bacterial Agents; Callithrix; Chromatography, Liquid; Drug Administration Schedule; Female; Francisella tularensis; Levofloxacin; Male; Ofloxacin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Treatment Outcome; Tularemia | 2010 |
Catheter-associated urinary tract infection IDSA guidelines: why the levofloxacin?
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Catheter-Related Infections; Humans; Levofloxacin; Ofloxacin; Practice Guidelines as Topic; Treatment Outcome; Urinary Tract Infections | 2010 |
Biofilm formation by Streptococcus pneumoniae strains and effects of human serum albumin, ibuprofen, N-acetyl-l-cysteine, amoxicillin, erythromycin, and levofloxacin.
Topics: Acetylcysteine; Amoxicillin; Anti-Bacterial Agents; Biofilms; Erythromycin; Humans; Ibuprofen; Levofloxacin; Ofloxacin; Serum Albumin; Streptococcus pneumoniae | 2010 |
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity | 2011 |
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline | 2010 |
Impact of recA on levofloxacin exposure-related resistance development.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromatography, High Pressure Liquid; Escherichia coli; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Rec A Recombinases; Staphylococcus aureus | 2010 |
The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel.
Topics: Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gene Expression Regulation; Humans; Kidney; Levofloxacin; Ofloxacin; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Transport; Structure-Activity Relationship; Transfection | 2010 |
Simultaneous determination of isoniazid, rifampicin, levofloxacin in mouse tissues and plasma by high performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antibiotics, Antitubercular; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Gatifloxacin; Intestine, Small; Isoniazid; Kidney; Least-Squares Analysis; Levofloxacin; Liver; Lung; Male; Methanol; Mice; Ofloxacin; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tissue Distribution | 2010 |
Characterization of bacterial infections in allogeneic hematopoietic stem cell transplant recipients who received prophylactic levofloxacin with either penicillin or doxycycline.
Topics: Antibiotic Prophylaxis; Bacterial Infections; Cohort Studies; Doxycycline; Drug Resistance, Bacterial; Hematopoietic Stem Cell Transplantation; Humans; Levofloxacin; Ofloxacin; Penicillins; Retrospective Studies; Transplantation, Homologous | 2010 |
Biodegradable levofloxacin nanoparticles for sustained ocular drug delivery.
Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Chickens; Chorioallantoic Membrane; Cornea; Drug Carriers; Drug Stability; Goats; Lactic Acid; Levofloxacin; Microbial Sensitivity Tests; Nanoparticles; Ofloxacin; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spectrophotometry, Infrared; Staphylococcus aureus; Surface Properties; X-Ray Diffraction | 2011 |
Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis.
Topics: Absorption; Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Bacterial Load; Biological Availability; Cell Line; Cell Proliferation; Cornea; Disease Models, Animal; Endothelial Cells; Eye; Female; Humans; Keratitis; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Orchidaceae; Plant Extracts; Polysaccharides; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tears; Treatment Outcome | 2010 |
Comparative antibiotic failure rates in the treatment of community-acquired pneumonia: Results from a claims analysis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cohort Studies; Community-Acquired Infections; Female; Humans; Insurance Claim Review; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Retrospective Studies; Risk Factors; Treatment Failure | 2010 |
[Septic shock due to fluoroquinolone-resistant Escherichia coli after trans-rectal prostate needle biopsy].
Topics: Biopsy, Needle; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Postoperative Complications; Rectum; Shock, Septic | 2010 |
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin | 2010 |
A single reversed-phase UPLC method for quantification of levofloxacin in aqueous humour and pharmaceutical dosage forms.
Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Levofloxacin; Linear Models; Ofloxacin; Ophthalmic Solutions; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Tablets; Time Factors | 2010 |
[Levofloxacin in children].
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Child; Community-Acquired Infections; Humans; Levofloxacin; Mycoplasma pneumoniae; Ofloxacin; Otitis Media; Pneumococcal Infections; Pneumonia; Sinusitis; Staphylococcus aureus; Streptococcus pneumoniae | 2010 |
Levofloxacin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin.
Topics: Anti-Bacterial Agents; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Levofloxacin; Ofloxacin; Stevens-Johnson Syndrome | 2010 |
Community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction. Role of antibiotic combination of linezolid plus levofloxacin.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Cerebral Infarction; Community-Acquired Infections; Drug Therapy, Combination; Humans; Levofloxacin; Linezolid; Male; Meningitis, Bacterial; Methicillin-Resistant Staphylococcus aureus; Ofloxacin; Oxazolidinones; Staphylococcal Infections | 2010 |
Outpatient treatment with intravenous antimicrobial therapy and oral levofloxacin in patients with febrile neutropenia and hematological malignancies.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Fever; Hematologic Neoplasms; Home Infusion Therapy; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Neutropenia; Ofloxacin; Retrospective Studies; Teicoplanin; Treatment Outcome | 2011 |
Sonochemical decomposition of levofloxacin in aqueous solution.
Topics: Anti-Bacterial Agents; Carbon Tetrachloride; Hydrogen-Ion Concentration; Levofloxacin; Ofloxacin; tert-Butyl Alcohol; Ultrasonics; Waste Disposal, Fluid | 2010 |
Effect of N-1/c-8 ring fusion and C-7 ring structure on fluoroquinolone lethality.
Topics: Anti-Infective Agents; Chloramphenicol; Escherichia coli; Fluoroquinolones; Levofloxacin; Ofloxacin; Oxazines; Structure-Activity Relationship | 2010 |
In vitro activities of several antimicrobial agents against recently isolated and genotyped Chlamydia trachomatis urogenital serovars D through K.
Topics: Anti-Infective Agents; Azithromycin; Chlamydia trachomatis; Clarithromycin; Doxycycline; Erythromycin; Genotype; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2010 |
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Clarithromycin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lebanon; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Vancomycin | 2010 |
Urine opiate screening: false-positive result with levofloxacin.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cross Reactions; Elder Abuse; False Positive Reactions; Female; Humans; Immunoenzyme Techniques; Levofloxacin; Narcotics; Ofloxacin; Substance Abuse Detection | 2010 |
Independent behavior of commensal flora for carriage of fluoroquinolone-resistant bacteria in patients at admission.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Cohort Studies; Drug Resistance, Bacterial; Escherichia coli; Feces; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Nasal Cavity; Ofloxacin; Pharynx; Prospective Studies; Risk Factors; Staphylococcus; Streptococcus; Young Adult | 2010 |
Lymphomatoid hypersensitivity reaction to levofloxacin during autologous stem cell transplantation: a potential diagnostic pitfall in patients treated for lymphoma or leukemia.
Topics: Anti-Bacterial Agents; Biomarkers, Tumor; Diagnosis, Differential; Drug Eruptions; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunohistochemistry; Leukemia; Levofloxacin; Lymphoma; Lymphoma, Mantle-Cell; Middle Aged; Ofloxacin; T-Lymphocytes; Transplantation, Autologous | 2011 |
[Clinical features and delayed aftereffects of Legionellosis pneumonia during an epidemic outbreak].
Topics: Anti-Bacterial Agents; Azithromycin; Disease Outbreaks; Female; Humans; Legionellosis; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Russia; Treatment Outcome; Water Supply | 2010 |
Risk factors and mechanisms of fluoroquinolone resistance in 156 Escherichia coli strains clinically isolated from urinary tract infections.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Ofloxacin; Risk Factors; Sequence Analysis, DNA; Urinary Tract Infections | 2011 |
Tsukamurella tyrosinosolvens and Rhizobium radiobacter sepsis presenting with septic pulmonary emboli.
Topics: Actinomycetales; Actinomycetales Infections; Aged; Agrobacterium tumefaciens; Anti-Bacterial Agents; Catheter-Related Infections; Catheterization, Central Venous; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pulmonary Embolism; Radiography, Thoracic; Sepsis; Tomography, X-Ray Computed | 2011 |
[A case of mucosa-associated lymphoid tissue lymphoma with penicillin allergy successfully treated with levofloxacin, minomycin and rabeprazole].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biopsy; Drug Hypersensitivity; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Lymphoma, B-Cell, Marginal Zone; Middle Aged; Minocycline; Ofloxacin; Penicillins; Rabeprazole | 2010 |
Resistance of Helicobacter pylori to antibiotics from 2000 to 2009 in Shanghai.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; China; Clarithromycin; Drug Resistance, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Middle Aged; Ofloxacin; Retrospective Studies; Young Adult | 2010 |
[Epidemiological analysis of Streptococcus pneumoniae in Gifu prefecture].
Topics: Humans; Japan; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillin Resistance; Penicillin-Binding Proteins; Streptococcus pneumoniae | 2010 |
Liver abscess and empyema due to Lactococcus lactis cremoris.
Topics: Adult; Anti-Bacterial Agents; Cefotaxime; Drainage; Empyema; Gram-Positive Bacterial Infections; Humans; Lactococcus lactis; Levofloxacin; Liver Abscess; Male; Microbial Sensitivity Tests; Ofloxacin; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed | 2010 |
Novel lipophilic 7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid derivatives as potential antitumor agents: improved synthesis and in vitro evaluation.
Topics: Amides; Antineoplastic Agents; Benzene Derivatives; Carboxylic Acids; Cell Line, Tumor; Cell Proliferation; Esters; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Levofloxacin; Ofloxacin | 2010 |
Identification of potentially involved proteins in levofloxacin resistance mechanisms in Coxiella burnetii.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Chlorocebus aethiops; Coxiella burnetii; Drug Resistance, Bacterial; Levofloxacin; Mass Spectrometry; Ofloxacin; Proteome; Proteomics; Up-Regulation; Vero Cells | 2011 |
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections.
Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Epithelial Cells; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Levofloxacin; Ofloxacin; Pneumonia; Tobramycin | 2011 |
High rates of quinolone resistance among urinary tract infections in the ED.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Bacterial; Emergency Service, Hospital; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Quinolones; Retrospective Studies; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections; Young Adult | 2012 |
Postantibiotic effects of tigecycline, colistin sulfate, and levofloxacin alone or tigecycline-colistin sulfate and tigecycline-levofloxacin combinations against Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Thienamycins; Tigecycline | 2010 |
Eradication of Chlamydia trachomatis parallels symptom regression in chronic bacterial prostatitis patients treated with a fluoroquinolone-macrolide combination.
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, Combination; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate-Specific Antigen; Prostatitis; Semen; Urethra | 2010 |
Effects of levofloxacin, moxifloxacin and prulifloxacin on murine gut colonization by Candida albicans.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Candida albicans; Dioxolanes; Feces; Fluoroquinolones; Gastrointestinal Tract; Levofloxacin; Male; Mice; Mice, Inbred ICR; Models, Animal; Moxifloxacin; Ofloxacin; Piperazines; Quinolines; Sodium Chloride | 2011 |
Impact of bloodstream infections on outcome and the influence of prophylactic oral antibiotic regimens in allogeneic hematopoietic SCT recipients.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cohort Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Levofloxacin; Male; Ofloxacin; Retrospective Studies; Transplantation, Homologous; Treatment Outcome; Young Adult | 2011 |
Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages.
Topics: Anti-Bacterial Agents; Bacterial Load; Bacterial Typing Techniques; Erythromycin; Humans; Legionella; Legionellosis; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Microbial Viability; Minocycline; Ofloxacin; Serotyping; Tigecycline; Time Factors | 2011 |
Reduced levofloxacin susceptibility in clinical respiratory isolates of Haemophilus influenzae is not yet associated with mutations in the DNA gyrase and topoisomerase II genes in Korea.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerases, Type II; Haemophilus influenzae; Korea; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin | 2011 |
Possible case of levofloxacin-induced thrombocytopenia.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Female; Humans; Levofloxacin; Mouth Neoplasms; Ofloxacin; Platelet Count; Pneumonia, Bacterial; Thrombocytopenia | 2011 |
Significant ecological impact on the progression of fluoroquinolone resistance in Escherichia coli with increased community use of moxifloxacin, levofloxacin and amoxicillin/clavulanic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Aza Compounds; Bacteremia; Drug Resistance, Bacterial; Drug Utilization; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; Hospitals; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Spain; Young Adult | 2011 |
Clinical efficacy of levofloxacin 500 mg once daily for 7 days for patients with non-gonococcal urethritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Humans; Leukocyte Count; Levofloxacin; Male; Middle Aged; Mycoplasma genitalium; Mycoplasma Infections; Ofloxacin; Treatment Outcome; Ureaplasma Infections; Ureaplasma urealyticum; Urethritis; Young Adult | 2011 |
[Electrophysiological effect of levofloxacin on ventricular myocytes in guinea pig].
Topics: Animals; Guinea Pigs; Levofloxacin; Membrane Potentials; Myocytes, Cardiac; Ofloxacin; Patch-Clamp Techniques | 2007 |
Case of Legionella pneumonia complicated with pulmonary thromboembolism.
Topics: Anti-Bacterial Agents; Anticoagulants; Community-Acquired Infections; Heparin; Humans; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Ofloxacin; Pulmonary Embolism; Thrombophilia | 2010 |
Genotypic resistance in Helicobacter pylori strains correlates with susceptibility test and treatment outcomes after levofloxacin- and clarithromycin-based therapies.
Topics: Adult; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Female; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Randomized Controlled Trials as Topic; RNA, Ribosomal, 23S; Treatment Outcome | 2011 |
Levofloxacin in first-line eradication regimens for Helicobacter pylori: better test antibiotic susceptibility before treating.
Topics: Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Ofloxacin | 2011 |
Sequential therapy for Helicobacter pylori eradication: is levofloxacin better?
Topics: Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Ofloxacin | 2011 |
Acute hepatitis associated with the use of levofloxacin.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Humans; Levofloxacin; Liver Function Tests; Male; Ofloxacin; Pneumonia; Treatment Outcome | 2010 |
In vitro intracellular activity and in vivo efficacy of modithromycin, a novel bicyclolide, against Legionella pneumophila.
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bridged-Ring Compounds; Cell Line; Cells, Cultured; Clarithromycin; Disease Models, Animal; Humans; Ketolides; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Macrolides; Mice; Microbial Sensitivity Tests; Ofloxacin | 2011 |
Antibiotics and observation have a similar impact on asymptomatic patients with a raised PSA.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Biopsy, Needle; Epidemiologic Methods; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 2011 |
Aerosolized Bacillus anthracis infection in New Zealand white rabbits: natural history and intravenous levofloxacin treatment.
Topics: Aerosols; Animals; Anthrax; Anti-Bacterial Agents; Antigens, Bacterial; Bacillus anthracis; Bacteremia; Biomarkers; Female; Levofloxacin; Male; Ofloxacin; Rabbits; Spores, Bacterial; Time Factors | 2010 |
Ternary copper(II) complexes of levofloxacin and phenanthroline derivatives: in-vitro antibacterial, DNA interactions, and SOD-like activity.
Topics: Anti-Bacterial Agents; Bacteria; Copper; DNA; DNA Cleavage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Levofloxacin; Ofloxacin; Organometallic Compounds; Phenanthrolines; Structure-Activity Relationship; Superoxide Dismutase | 2011 |
[Mutant prevention concentrations of garenoxacin against Streptococcus pneumoniae isolates from otorhinolaryngological infections].
Topics: Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Mutation; Ofloxacin; Otorhinolaryngologic Diseases; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae | 2010 |
Allergy to quinolones: low cross-reactivity to levofloxacin.
Topics: Adult; Aged, 80 and over; Basophils; Cross Reactions; Drug Hypersensitivity; Female; Flow Cytometry; Humans; Hypersensitivity, Immediate; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Skin Tests; Young Adult | 2010 |
Levofloxacin-associated Achilles tendinitis in a patient with chronic kidney disease stage 5.
Topics: Achilles Tendon; Bronchitis; Female; Humans; Kidney Failure, Chronic; Levofloxacin; Magnetic Resonance Imaging; Middle Aged; Ofloxacin; Tendinopathy | 2011 |
Mutant prevention concentration-based pharmacokinetic/pharmacodynamic indices as dosing targets for suppressing the enrichment of levofloxacin-resistant subpopulations of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus | 2011 |
Levofloxacin cures experimental pneumonic plague in African green monkeys.
Topics: Animals; Anti-Bacterial Agents; Bacteremia; Chlorocebus aethiops; Disease Models, Animal; Infusions, Intravenous; Levofloxacin; Lung; Ofloxacin; Plague; Primate Diseases; Radiography, Thoracic; Survival Analysis | 2011 |
Biowaiver monographs for immediate release solid oral dosage forms: levofloxacin.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Drug and Narcotic Control; Excipients; Humans; Levofloxacin; Ofloxacin; Solubility; Tablets | 2011 |
Levofloxacin for the treatment of Mycoplasma pneumoniae-associated meningoencephalitis in childhood.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Female; Humans; Injections, Intravenous; Levofloxacin; Male; Meningoencephalitis; Mycoplasma Infections; Mycoplasma pneumoniae; Ofloxacin | 2011 |
Clonal spread of levofloxacin-resistant streptococcus pneumoniae invasive isolates in Madrid, Spain, 2007 to 2009.
Topics: DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Levofloxacin; Ofloxacin; Phylogeny; Sequence Analysis, DNA; Serotyping; Spain; Streptococcus pneumoniae | 2011 |
Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Models, Biological; Models, Theoretical; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Staphylococcus aureus; Time Factors | 2011 |
Evaluation by Monte Carlo simulation of levofloxacin dosing for complicated urinary tract infections caused by Escherichia coli or Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Area Under Curve; Computer Simulation; Databases, Factual; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Statistical; Monte Carlo Method; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Urinary Tract Infections | 2011 |
Evidence for persisters in Staphylococcus epidermidis RP62a planktonic cultures and biofilms.
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Biofilms; Drug Resistance, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Microscopy, Confocal; Ofloxacin; Staphylococcus epidermidis; Surface Properties; Time Factors; Vancomycin | 2011 |
In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp.
Topics: Anti-Bacterial Agents; Drug Combinations; Drug Therapy, Combination; Erythromycin; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Tetracycline; Ureaplasma; Ureaplasma Infections | 2011 |
Levofloxacin susceptibility testing for Helicobacter pylori in China: comparison of E-test and disk diffusion method.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin | 2011 |
Primary resistance of Helicobacter pylori to levofloxacin and moxifloxacine in Iran.
Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Iran; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Young Adult | 2012 |
Factors affecting drug encapsulation and stability of lipid-polymer hybrid nanoparticles.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Compounding; Drug Delivery Systems; Drug Stability; Lactic Acid; Levofloxacin; Lipids; Microscopy, Electron, Scanning; Nanoparticles; Ofloxacin; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Surface-Active Agents; Vitamin E; Water | 2011 |
[Practice management of chronic bacterial prostatitis with levofloxacin].
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Chronic Disease; Escherichia coli Infections; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prospective Studies; Prostatitis; Recurrence; Staphylococcal Infections | 2011 |
Consumption patterns and in vitro resistance of Streptococcus pneumoniae to fluoroquinolones.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2011 |
Erythema nodosum in kidney transplant recipient: a rare complication of pneumonia treatment.
Topics: Adult; Anti-Bacterial Agents; Erythema Nodosum; Female; Humans; Kidney Transplantation; Leg; Levofloxacin; Ofloxacin; Pneumonia, Bacterial; Skin | 2012 |
Antibacterial and synergy of a flavanonol rhamnoside with antibiotics against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Ceftazidime; Drug Synergism; Flavonols; Glycosides; Humans; Hypericum; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Ofloxacin; Quercetin; Sputum | 2011 |
Levofloxacin weight-adjusted dosing and pharmacokinetic disposition in a morbidly obese patient.
Topics: Anti-Bacterial Agents; Body Weight; Humans; Infusions, Intravenous; Levofloxacin; Middle Aged; Obesity, Morbid; Ofloxacin; Pneumococcal Infections | 2011 |
[Acute cholestatic hepatitis associated with levofloxacin].
Topics: Acute Disease; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin | 2011 |
Susceptibility of hamsters to infection by historic and epidemic BI Clostridium difficile strains during daily administration of three fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clostridioides difficile; Clostridium Infections; Cricetinae; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Mesocricetus; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Prohibitins; Quinolines | 2011 |
In vitro activities of ceftobiprole combined with amikacin or levofloxacin against Pseudomonas aeruginosa: evidence of a synergistic effect using time-kill methodology.
Topics: Amikacin; Anti-Bacterial Agents; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Stem Cells; Time Factors | 2011 |
[Regional difference of antibiotic resistance of helicobacter pylori strains in Korea].
Topics: Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Female; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Republic of Korea; Tetracycline | 2011 |
[Levofloxacin and other fluoroquinolones in therapy of respiratory tract infections].
Topics: Administration, Oral; Anti-Bacterial Agents; Biological Availability; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections | 2011 |
Efficient penetration into aqueous humor by administration of oral and topical levofloxacin.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cataract Extraction; Chromatography, High Pressure Liquid; Endophthalmitis; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Postoperative Complications; Reproducibility of Results; Tissue Distribution; Vitreous Body | 2011 |
JNJ-Q2, a new fluoroquinolone with potent in vitro activity against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcus aureus | 2011 |
Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Dose-Response Relationship, Drug; Doxycycline; Erythromycin; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Reproducibility of Results; Roxithromycin; Tetracycline; Time Factors; Ureaplasma Infections; Ureaplasma urealyticum | 2011 |
[Lack of levofloxacin and moxyfloxacin efficacy in experimental plague of albino mice infected with nalidixic acid resistant pathogen (Nal(r))].
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Lethal Dose 50; Levofloxacin; Mice; Models, Animal; Nalidixic Acid; Ofloxacin; Plague; Virulence; Yersinia pestis | 2010 |
High Helicobacter pylori resistance to metronidazole but zero or low resistance to clarithromycin, levofloxacin, and other antibiotics in Malaysia.
Topics: Adult; Aged; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Multiple, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prospective Studies | 2011 |
Comparison of drug sensitivity and genotypes of clinically isolated strains of levofloxacin-resistant Streptococcus pneumoniae obtained from Okinawa Island, the Japanese main island and Hong Kong.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cluster Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genotype; Hong Kong; Humans; Japan; Levofloxacin; Microbial Sensitivity Tests; Molecular Typing; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Sequence Analysis, DNA; Streptococcus pneumoniae | 2011 |
Application of levofloxacine in the second phase of sequential therapy regimen for Helicobacter pylori eradication: is it a good choice?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Dyspepsia; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Levofloxacin; Male; Ofloxacin; Prospective Studies; Treatment Outcome | 2011 |
Blood stream infections after allogeneic stem cell transplantation: a single-center experience with the use of levofloxacin prophylaxis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Candida; Candida albicans; Candidemia; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Levofloxacin; Male; Middle Aged; Ofloxacin; Transplantation, Homologous; Young Adult | 2012 |
Fluoroquinolones influence the intracellular calcium handling in individuals susceptible to malignant hyperthermia.
Topics: Animals; Calcium; Ciprofloxacin; Disease Susceptibility; Fluoroquinolones; Levofloxacin; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Nucleic Acid Synthesis Inhibitors; Ofloxacin; Swine | 2011 |
[Validity of using imipenem as a representative carbapenems and levofloxacin as a representative fluoroquinolones in antibiotics susceptibility test for enterobacteriaceae].
Topics: Anti-Bacterial Agents; Carbapenems; Drug Resistance, Bacterial; Enterobacteriaceae; Fluoroquinolones; Imipenem; Levofloxacin; Ofloxacin | 2011 |
Comparison of the chromatographic behavior of levofloxacin, ciprofloxacin and moxifloxacin on various HPLC phases.
Topics: Anti-Bacterial Agents; Aza Compounds; Calixarenes; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Indicators and Reagents; Ions; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Reference Standards; Solutions | 2011 |
Susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada.
Topics: Anti-Bacterial Agents; Aza Compounds; Binding Sites; Canada; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae | 2011 |
First case of Legionella pneumophila native valve endocarditis.
Topics: Adult; Aortic Valve; Community-Acquired Infections; Endocarditis, Bacterial; Female; Humans; Immunosuppression Therapy; Legionella pneumophila; Levofloxacin; Ofloxacin; Rifampin | 2011 |
[Antibioprophylaxis in ocular surgery: AFSSAPS recommendations].
Topics: Administration, Oral; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime; Contraindications; Drug Resistance, Bacterial; Endophthalmitis; Fluoroquinolones; Humans; Injections, Intraocular; Intravitreal Injections; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Practice Guidelines as Topic; Tablets | 2011 |
Long-term fluoroquinolone use before the prostate biopsy may increase the risk of sepsis caused by resistant microorganisms.
Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Biopsy, Needle; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Risk Factors; Sepsis; Time Factors | 2011 |
Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009.
Topics: Acetamides; Bacterial Toxins; Ceftaroline; Cephalosporins; Clindamycin; Daptomycin; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Exotoxins; Leukocidins; Levofloxacin; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mupirocin; Ofloxacin; Oxacillin; Oxazolidinones; Polymerase Chain Reaction; Staphylococcus aureus; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Vancomycin | 2011 |
Pharmacokinetics of multiple-dose levofloxacin in hemodialysis patients.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Half-Life; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pyelonephritis; Renal Dialysis | 2011 |
Retrospective comparison of levofloxacin and moxifloxacin on multidrug-resistant tuberculosis treatment outcomes.
Topics: Adult; Antitubercular Agents; Aza Compounds; Case-Control Studies; Chi-Square Distribution; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Humans; Levofloxacin; Logistic Models; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Odds Ratio; Ofloxacin; Quinolines; Recurrence; Remission Induction; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2011 |
Epidemiological features and resistance pattern in uropathogens isolated from chronic bacterial prostatitis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enterococcus faecalis; Escherichia coli; Escherichia coli Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Prostatitis; Young Adult | 2011 |
Helicobacter pylori eradication by sitafloxacin-lansoprazole combination and sitafloxacin pharmacokinetics in Mongolian gerbils and its in vitro activity and resistance development.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Bacterial Agents; Drug Combinations; Fluoroquinolones; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Lansoprazole; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin | 2011 |
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis | 2011 |
Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice.
Topics: Actins; Analysis of Variance; Animals; Anti-Infective Agents; Cecum; Colitis; Colon; Cytokines; Female; Fibrosis; Levofloxacin; Mice; Mice, Inbred CBA; Ofloxacin; Salmonella Infections, Animal; Salmonella typhimurium; Time Factors | 2012 |
Concurrent postpartum uterine and abdominal wall dehiscence and Streptococcus anginosus infection.
Topics: Abdominal Wall; Acute Disease; Adolescent; Anti-Bacterial Agents; Ascitic Fluid; Cefazolin; Cesarean Section; Chorioamnionitis; Female; Humans; Levofloxacin; Metronidazole; Ofloxacin; Postoperative Complications; Postpartum Period; Pregnancy; Streptococcal Infections; Streptococcus anginosus; Surgical Wound Dehiscence; Uterus; Vasculitis | 2011 |
Pharmacokinetic/pharmacodynamic modelling of the bactericidal activity of free lung concentrations of levofloxacin and gatifloxacin against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Area Under Curve; Culture Media; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Lung; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae | 2011 |
Prevalence of plasmid-mediated quinolone resistance determinants in Citrobacter freundii isolates from Anhui province, PR China.
Topics: China; Ciprofloxacin; Citrobacter freundii; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Ofloxacin; Plasmids | 2011 |
Can oral levofloxacin cause of flexor digitorum profundus rupture?
Topics: Administration, Oral; Anti-Bacterial Agents; Finger Injuries; Humans; Levofloxacin; Ofloxacin; Rupture; Tendon Injuries | 2011 |
Interaction of Zn(II) with quinolone drugs: structure and biological evaluation.
Topics: Animals; Anti-Bacterial Agents; Cattle; Coordination Complexes; Crystallography, X-Ray; DNA; Fluoroquinolones; Humans; Levofloxacin; Models, Molecular; Ofloxacin; Protein Binding; Quinolones; Serum Albumin; Serum Albumin, Bovine; Zinc | 2011 |
Sacroiliitis caused by Salmonella typhi: a case report.
Topics: Anti-Bacterial Agents; Blood Sedimentation; C-Reactive Protein; Diarrhea; Humans; Levofloxacin; Magnetic Resonance Imaging; Male; Ofloxacin; Pelvic Bones; Radiography; Sacroiliac Joint; Sacroiliitis; Salmonella typhi; Typhoid Fever; Vancomycin; Young Adult | 2011 |
Primary and secondary clarithromycin, metronidazole, amoxicillin and levofloxacin resistance to Helicobacter pylori in southern Poland.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Multiple, Bacterial; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Ofloxacin; Poland | 2011 |
Cethromycin-mediated protection against the plague pathogen Yersinia pestis in a rat model of infection and comparison with levofloxacin.
Topics: Animals; Anti-Bacterial Agents; Female; Ketolides; Levofloxacin; Ofloxacin; Plague; Rats; Yersinia pestis | 2011 |
Risk factors for bacteraemia attributable to Pseudomonas aeruginosa resistant to imipenem, levofloxacin, or gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Gentamicins; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Middle Aged; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Young Adult | 2011 |
Hereditary neuropathy unmasked by levofloxacin.
Topics: Anti-Bacterial Agents; Charcot-Marie-Tooth Disease; Diagnosis, Differential; Family Health; Humans; Hypesthesia; Levofloxacin; Male; Middle Aged; Mobility Limitation; Muscle Weakness; Ofloxacin; Pain; Prostatitis; Severity of Illness Index | 2011 |
[A case of legionellesis pneumonia verified by isolation of Legionella pneumophila serogroup 1 from bronchoalveolar lavage fluid treated with levofloxacine and tigecycline].
Topics: Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Drug Therapy, Combination; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Male; Middle Aged; Minocycline; Ofloxacin; Pneumonia, Bacterial; Tigecycline; Treatment Outcome | 2011 |
The effects of levofloxacin on rabbit anterior cruciate ligament cells in vitro.
Topics: Animals; Anterior Cruciate Ligament; Anti-Bacterial Agents; Cells, Cultured; Dose-Response Relationship, Drug; In Vitro Techniques; Levofloxacin; Microscopy, Electron, Transmission; Ofloxacin; Rabbits; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Prevalence of fluoroquinolone-resistant Escherichia coli before and incidence of acute bacterial prostatitis after prostate biopsy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy, Needle; Carbapenems; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Feces; Fluoroquinolones; Humans; Incidence; Levofloxacin; Male; Middle Aged; Ofloxacin; Prevalence; Prostate; Prostatitis; Rectum | 2011 |
[Levofloxacin. expediency of high-dose regimens in therapy of lower respiratory tract infections].
Topics: Community-Acquired Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Pneumonia; Pulmonary Disease, Chronic Obstructive | 2011 |
Mechanisms of and risk factors for fluoroquinolone resistance in clinical Enterococcus faecalis isolates from patients with urinary tract infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resistance, Bacterial; Enterococcus faecalis; Female; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Ofloxacin; Risk Factors; Urinary Tract Infections; Young Adult | 2011 |
Prevalence of Corynebacterium ulcerans in dogs in Osaka, Japan.
Topics: Animals; Anti-Bacterial Agents; Carrier State; Clindamycin; Corynebacterium; Corynebacterium Infections; DNA, Bacterial; Dog Diseases; Dogs; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Japan; Levofloxacin; Male; Molecular Sequence Data; Molecular Typing; Ofloxacin; Prevalence; Sequence Analysis, DNA | 2012 |
Antimicrobial therapy for asymptomatic patients with elevated prostate-specific antigen: can the change in prostate-specific antigen reliably guide prostate biopsy decisions?
Topics: Aged; Anti-Bacterial Agents; Asymptomatic Diseases; Biopsy; Diagnostic Errors; Drug Administration Schedule; Egypt; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatitis; Sensitivity and Specificity; Time Factors; Treatment Outcome; Up-Regulation | 2011 |
[The effectiveness of intraocular delivery of 5-fluoroquinolones for prophylaxis of intraocular infection].
Topics: Anti-Bacterial Agents; Aza Compounds; Eye Infections, Bacterial; Eye Injuries; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intraocular; Levofloxacin; Male; Military Medicine; Moxifloxacin; Ofloxacin; Quinolines; Warfare | 2011 |
Optimizing biliary stent patency by coating with hydrophobin alone or hydrophobin and antibiotics or heparin: an in vitro proof of principle study.
Topics: Anti-Bacterial Agents; Bile; Bile Ducts; Biliary Tract; Coated Materials, Biocompatible; Cost-Benefit Analysis; Fungal Proteins; Heparin; Humans; In Vitro Techniques; Levofloxacin; Microscopy, Electron, Scanning; Ofloxacin; Plastics; Stents | 2011 |
Spondylodiscitis due to Sallmonela in an immunocompetent patient.
Topics: Adult; Anti-Bacterial Agents; Discitis; Humans; Immunocompetence; Levofloxacin; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Ofloxacin; Salmonella Infections | 2011 |
Fixed drug eruption: levofloxacin, another culprit drug.
Topics: Aged; Anti-Infective Agents; Drug Eruptions; Female; Humans; Levofloxacin; Ofloxacin; Skin; Skin Tests | 2012 |
Prevalence of efflux-mediated ciprofloxacin and levofloxacin resistance in recent clinical isolates of Pseudomonas aeruginosa and its reversal by the efflux pump inhibitors 1-(1-naphthylmethyl)-piperazine and phenylalanine-arginine-β-naphthylamide.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dipeptides; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Piperazine; Piperazines; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections | 2012 |
Antipneumococcal activity of ulifloxacin compared to levofloxacin and ciprofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pneumococcal Infections; Streptococcus pneumoniae | 2011 |
Evaluation of levofloxacin release characteristics from a human foldable capsular vitreous body in vitro.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Delivery Systems; Endophthalmitis; Humans; Levofloxacin; Microscopy, Electron, Scanning; Ofloxacin; Tandem Mass Spectrometry; Time Factors; Vitreous Body | 2012 |
Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacte
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Cell Line, Tumor; Ciprofloxacin; Dimerization; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Neoplasms; Ofloxacin | 2011 |
Empirical therapy with ceftazidime combined with levofloxacin or once-daily amikacin for febrile neutropenia in patients with neoplasia: a prospective comparative study.
Topics: Aged; Amikacin; Anti-Bacterial Agents; Ceftazidime; Drug Therapy, Combination; Female; Fever of Unknown Origin; Humans; Kidney Diseases; Levofloxacin; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Prospective Studies; Survival Analysis; Treatment Outcome | 2012 |
In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin.
Topics: Animals; Cell Line, Tumor; Chi-Square Distribution; Chromosome Aberrations; Computer Simulation; Cricetinae; Drug Contamination; Levofloxacin; Lymphoma; Mice; Molecular Structure; Mutagenicity Tests; Mutation; Ofloxacin; Oxides; Risk Assessment; Software; Structure-Activity Relationship | 2012 |
Levofloxacin-induced rhabdomyolysis in a hemodialysis patient.
Topics: Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Ofloxacin; Renal Dialysis; Rhabdomyolysis | 2012 |
Controlled release of levofloxacin sandwiched between two plasma polymerized layers on a solid carrier.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Ofloxacin; Polymerization | 2011 |
[Evaluation of tuberculosis treatment including levofloxacin (LVFX) in cases who could not continue standard regimen].
Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis; Tuberculosis, Pulmonary | 2011 |
In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods.
Topics: Anti-Bacterial Agents; Benzofurans; Clindamycin; Culture Media; Drug Resistance, Multiple, Bacterial; Drug Synergism; Erythromycin; Gentamicins; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Oxacillin | 2012 |
Oral Levofloxacin brings better results in treating endogenous Klebsiella pneumoniae endophthalmitis.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Ofloxacin; Oxazolidinones | 2012 |
Successful treatment of septic shock and respiratory failure due to leptospirosis and scrub typhus coinfection with penicillin, levofloxacin, and activated protein C.
Topics: Anti-Infective Agents; Antibodies, Bacterial; Humans; Leptospira; Leptospirosis; Levofloxacin; Male; Middle Aged; Ofloxacin; Orientia tsutsugamushi; Penicillins; Protein C; Respiratory Insufficiency; Scrub Typhus; Shock, Septic | 2012 |
Rapidly fatal community-acquired pneumonia due to Klebsiella pneumoniae complicated with acute myocarditis and accelerated idioventricular rhythm.
Topics: Accelerated Idioventricular Rhythm; Acidosis, Lactic; Acute Disease; Community-Acquired Infections; Electrocardiography; Fatal Outcome; Humans; Intensive Care Units; Klebsiella pneumoniae; Levofloxacin; Male; Middle Aged; Myocarditis; Ofloxacin; Pneumonia, Bacterial; Shock, Septic | 2012 |
Green preparation of antibiotic nanoparticle complex as potential anti-biofilm therapeutics via self-assembly amphiphile-polyelectrolyte complexation with dextran sulfate.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Calorimetry, Differential Scanning; Dextran Sulfate; Electrolytes; Green Chemistry Technology; Levofloxacin; Microbial Sensitivity Tests; Nanoparticles; Ofloxacin; Particle Size; Powders; Pseudomonas aeruginosa; Sodium Chloride; Surface-Active Agents; Thermogravimetry; X-Ray Diffraction | 2012 |
Effective antibiotics in combination against extreme drug-resistant Pseudomonas aeruginosa with decreased susceptibility to polymyxin B.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Phylogeny; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Thienamycins; Time Factors | 2011 |
Preparation and in vitro release of spray-dried chitosan microspheres for levofloxacin delivery.
Topics: Anti-Infective Agents, Local; Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Desiccation; Drug Carriers; Drug Compounding; Glutaral; Kinetics; Levofloxacin; Microscopy, Electron, Scanning; Microspheres; Ofloxacin; Particle Size; Solubility; Technology, Pharmaceutical | 2011 |
Polyelectrolyte complex materials consisting of antibacterial and cell-supporting layers.
Topics: Anti-Bacterial Agents; Biocompatible Materials; Cell Proliferation; Cell Survival; Chitosan; Drug Compounding; Escherichia coli; Fibroblasts; Levofloxacin; Microbial Viability; Ofloxacin; Polysaccharides, Bacterial; Titanium | 2012 |
A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid-polymer hybrid nanoparticles.
Topics: Desiccation; Drug Compounding; Dry Powder Inhalers; Excipients; Freeze Drying; Lactic Acid; Lecithins; Leucine; Levofloxacin; Mannitol; Microscopy, Electron, Scanning; Nanoparticles; Ofloxacin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol | 2012 |
Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli.
Topics: Anti-Bacterial Agents; Area Under Curve; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Gene Deletion; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Polymerase Chain Reaction; Quinolones; Real-Time Polymerase Chain Reaction | 2012 |
Relationship between urinary tract infection categorization and pathogens' antimicrobial susceptibilities.
Topics: Anti-Infective Agents; Catheter-Related Infections; Ceftazidime; Enterococcus faecalis; Escherichia coli; Humans; Inpatients; Japan; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Outpatients; Pseudomonas aeruginosa; Time Factors; Urinary Catheterization; Urinary Tract Infections; Urology Department, Hospital | 2012 |
Clinical and economic impact of a pharmacist-managed i.v.-to-p.o. conversion service for levofloxacin in Taiwan.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Costs; Female; Hospital Costs; Humans; Infusions, Intravenous; Length of Stay; Levofloxacin; Male; Middle Aged; Ofloxacin; Pharmacists; Pharmacy Service, Hospital; Retrospective Studies; Taiwan; Treatment Outcome | 2012 |
Method validation and determinations of levofloxacin, metronidazole and sulfamethoxazole in an aqueous pharmaceutical, urine and blood plasma samples using quantitative nuclear magnetic resonance spectrometry.
Topics: Humans; Levofloxacin; Magnetic Resonance Spectroscopy; Maleates; Metronidazole; Ofloxacin; Sensitivity and Specificity; Sulfamethoxazole; Temperature | 2012 |
Evaluation of the levofloxacin release characters from a rabbit foldable capsular vitreous body.
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Delivery Systems; Implants, Experimental; Levofloxacin; Linear Models; Ofloxacin; Rabbits; Tandem Mass Spectrometry; Vitreous Body | 2012 |
Comparison of moxifloxacin and levofloxacin in an epithelial disorder model using cultured rabbit corneal epithelial cell sheets.
Topics: Amnion; Animals; Anti-Bacterial Agents; Aza Compounds; Cells, Cultured; Corneal Diseases; Epithelium, Corneal; Female; Fluoroquinolones; Levofloxacin; Models, Biological; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines; Rabbits; Swine; Wound Healing | 2012 |
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA, Bacterial; DNA, Superhelical; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Ofloxacin; Plasmids; Tuberculosis | 2012 |
Activity of JNJ-Q2, a new fluoroquinolone, tested against contemporary pathogens isolated from patients with community-acquired bacterial pneumonia.
Topics: Anti-Bacterial Agents; Aza Compounds; Community-Acquired Infections; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Geography; Haemophilus influenzae; Humans; Inhibitory Concentration 50; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Pneumonia, Bacterial; Quinolines; Streptococcus pneumoniae | 2012 |
Antimicrobial susceptibility of Stenotrophomonas maltophilia isolates from a Korean tertiary care hospital.
Topics: Anti-Infective Agents; Hospitals; Korea; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Stenotrophomonas maltophilia; Trimethoprim, Sulfamethoxazole Drug Combination | 2012 |
Activity of sitafloxacin against extracellular and intracellular Staphylococcus aureus in vitro and in vivo: comparison with levofloxacin and moxifloxacin.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cell Line; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Space; Fluoroquinolones; Intracellular Space; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Peritonitis; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 2012 |
Prevalence of fluoroquinolone-resistant Escherichia coli O25:H4-ST131 (CTX-M-15-nonproducing) strains isolated in Japan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Child; Child, Preschool; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; Humans; Infant; Infant, Newborn; Japan; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prevalence; Young Adult | 2012 |
[Efficacy and tolerance of rezonizate in complex with fluoroquinolones or mycobutin on a model of experimental murine tuberculosis].
Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug Therapy, Combination; Drug Tolerance; Fluoroquinolones; Gatifloxacin; Isoxazoles; Levofloxacin; Mice; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Rifabutin; Tuberculosis | 2011 |
Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.
Topics: Animals; Anti-Infective Agents, Local; Colony Count, Microbial; Conjunctival Diseases; Cornea; Eye; Female; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Keratitis; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 2012 |
Molecular epidemiology of fluoroquinolone resistance in invasive clinical isolates of Streptococcus pneumoniae in Seville.
Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Fluoroquinolones; Humans; Infant; Job Syndrome; Levofloxacin; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pneumococcal Infections; Reserpine; Serotyping; Spain; Streptococcus pneumoniae | 2012 |
Chromosomal mutations responsible for fluoroquinolone resistance in Ureaplasma species in the United States.
Topics: Anti-Bacterial Agents; Chromosomes, Bacterial; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Isoenzymes; Levofloxacin; Longitudinal Studies; Microbial Sensitivity Tests; Mutation; Ofloxacin; Sequence Analysis, DNA; United States; Ureaplasma; Ureaplasma Infections | 2012 |
Critical appraisal of air pouch infection model in rats.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Exudates and Transudates; Female; Gentamicins; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rats; Rats, Wistar; Staphylococcus aureus; Vancomycin | 2012 |
Oral levofloxacin-induced optic neuritis progressing in loss of vision.
Topics: Administration, Oral; Anti-Bacterial Agents; Ethmoid Sinusitis; Humans; Levofloxacin; Male; Maxillary Sinusitis; Middle Aged; Ofloxacin; Optic Neuritis; Vision Disorders | 2012 |
Levofloxacin-induced delirium: is it a dangerous drug in patients with renal dysfunction?
Topics: Anti-Bacterial Agents; Delirium; Follow-Up Studies; Humans; Levofloxacin; Magnetic Resonance Imaging; Male; Middle Aged; Ofloxacin; Pneumonia; Renal Insufficiency; Tomography, X-Ray Computed | 2012 |
Optimization, in vitro-in vivo evaluation, and short-term tolerability of novel levofloxacin-loaded PLGA nanoparticle formulation.
Topics: Animals; Antitubercular Agents; Area Under Curve; In Vitro Techniques; Lactic Acid; Levofloxacin; Mice; Microscopy, Electron, Scanning; Nanoparticles; Ofloxacin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared; Tissue Distribution | 2012 |
Safety profile of enantiomers vs. racemic mixtures: it's the same?
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Cetirizine; Citalopram; Databases, Factual; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Omeprazole; Stereoisomerism; Young Adult | 2012 |
Photolocalized purpura during levofloxacin therapy.
Topics: Aged; Cystitis; Female; Humans; Levofloxacin; Ofloxacin; Purpura; Sunlight | 2012 |
[In vitro antibiotic susceptibility to fluoroquinolones].
Topics: Acanthamoeba Keratitis; Anti-Bacterial Agents; Aza Compounds; Body Fluids; Ciprofloxacin; Colombia; Conjunctivitis, Bacterial; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacterial; Eye Infections, Fungal; Eye Infections, Parasitic; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies | 2012 |
Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (pages.
Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Asian People; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Regression Analysis; Retrospective Studies; White People; Young Adult | 2012 |
[Bilateral Achilles tendon rupture following levofloxacin and glucocorticoid use].
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Casts, Surgical; Female; Glucocorticoids; Humans; Levofloxacin; Ofloxacin; Pneumonia; Rupture | 2012 |
Severe hypoglycemia associated with levofloxacin in Type 2 diabetic patients receiving polytherapy: two case reports.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Polypharmacy; Risk Assessment; Severity of Illness Index | 2012 |
Is Helicobacter pylori antibiotic resistance surveillance needed and how can it be delivered?
Topics: Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Microbial; Dyspepsia; Endoscopy; England; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Ofloxacin; Risk Factors; Wales | 2012 |
Synthesis, characterization and antibacterial studies of a copper(II) levofloxacin ternary complex.
Topics: Anti-Bacterial Agents; Copper; Escherichia coli; Escherichia coli Infections; Levofloxacin; Ofloxacin | 2012 |
[Localized inflammatory alopecia of the scalp: an unusual presentation of tularemia].
Topics: Alopecia; Anti-Bacterial Agents; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Lymphatic Diseases; Middle Aged; Ofloxacin; Scalp; Skin Diseases, Papulosquamous; Tularemia | 2012 |
Ex vivo models to evaluate the role of ocular melanin in trans-scleral drug delivery.
Topics: Administration, Ophthalmic; Animals; Binding Sites; Bruch Membrane; Choroid; Diffusion; Eye Color; In Vitro Techniques; Levofloxacin; Melanins; Methylene Blue; Methylprednisolone Hemisuccinate; Ofloxacin; Permeability; Pharmaceutical Preparations; Propranolol; Sclera; Swine | 2012 |
Characterizations of clinical isolates of clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin (OPT-80) and rifaximin: a multicenter study in Taiwan.
Topics: Anti-Infective Agents; Aza Compounds; Bacterial Proteins; Clostridioides difficile; Fluoroquinolones; Gemifloxacin; Glycosides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Rifamycins; Rifaximin; Taiwan; Vancomycin | 2012 |
gyrA/B fluoroquinolone resistance allele profiles amongst Mycobacterium tuberculosis isolates from mainland China.
Topics: Alleles; China; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 2012 |
Levofloxacin-induced tendinopathy of the hip.
Topics: Anti-Bacterial Agents; Hip; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tendinopathy | 2012 |
Improvement of apathy after levofloxacin treatment: an N-of-1 study.
Topics: Aged; Apathy; Behavioral Symptoms; Drug Administration Schedule; Humans; Hydrocephalus, Normal Pressure; Levofloxacin; Male; Nucleic Acid Synthesis Inhibitors; Ofloxacin; Psychiatric Status Rating Scales | 2012 |
Levofloxacin neurotoxicity and non-convulsive status epilepticus (NCSE): a case report.
Topics: Electroencephalography; Female; Humans; Levofloxacin; Magnetic Resonance Imaging; Middle Aged; Neurotoxicity Syndromes; Ofloxacin; Spinal Puncture; Status Epilepticus | 2012 |
Induction of mycobacterial resistance to quinolone class antimicrobials.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines | 2012 |
[Efficacy of levofloxacin 500 mg for middle ear diseases].
Topics: Adult; Anti-Bacterial Agents; Ear Diseases; Ear, Middle; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Otitis Media | 2012 |
Comparative in vitro activity of sitafloxacin against bacteria isolated from Thai patients with urinary tract infections and lower respiratory tract infections.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Respiratory Tract Infections; Thailand; Urinary Tract Infections | 2012 |
Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Child; Child, Preschool; Clarithromycin; Drug Resistance, Bacterial; Drug Utilization; Europe; Female; Helicobacter pylori; Humans; Infant; Infant, Newborn; Levofloxacin; Linear Models; Logistic Models; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Ofloxacin; Prospective Studies; Risk Factors; Surveys and Questionnaires; Young Adult | 2013 |
Comparative in vitro efficacies of ethanol-, EDTA- and levofloxacin-based catheter lock solutions on eradication of Stenotrophomonas maltophilia biofilms.
Topics: Anti-Bacterial Agents; Argentina; Bacteremia; Biofilms; Catheter-Related Infections; Catheters, Indwelling; Chelating Agents; Colony Count, Microbial; Edetic Acid; Ethanol; Hospitals, University; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Solutions; Stenotrophomonas maltophilia | 2012 |
Letter: third-line rescue therapy with levofloxacin after failure of two treatments to eradicate Helicobacter pylori infection.
Topics: Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin; Proton Pump Inhibitors; Time Factors; Treatment Outcome | 2012 |
Levofloxacin inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells.
Topics: Anti-Bacterial Agents; Cells, Cultured; Cytokines; Epithelial Cells; Humans; Intercellular Adhesion Molecule-1; Levofloxacin; NF-kappa B; Ofloxacin; Picornaviridae Infections; Receptors, Virus; Respiratory Mucosa; Rhinovirus; RNA, Viral; Trachea | 2012 |
Development of an LC-MS method for determination of three active constituents of Shuang-huang-lian injection in rat plasma and its application to the drug interaction study of Shuang-huang-lian freeze-dried powder combined with levofloxacin injection.
Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Herb-Drug Interactions; Levofloxacin; Male; Mass Spectrometry; Ofloxacin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Rutin | 2012 |
Understanding the dehydration of levofloxacin hemihydrate.
Topics: Anti-Bacterial Agents; Calorimetry, Differential Scanning; Crystallography, X-Ray; Desiccation; Levofloxacin; Magnetic Resonance Spectroscopy; Models, Molecular; Ofloxacin; Powder Diffraction; Spectrum Analysis, Raman; Technology, Pharmaceutical; Temperature; Thermogravimetry; Water | 2012 |
The effect of levofloxacin and moxifloxacin on cardiovascular functions of rats with streptozotocin-induced diabetes.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Biological Factors; Blood Glucose; Bradycardia; Cardiovascular System; Diabetes Mellitus, Experimental; Electrocardiography; Endothelium, Vascular; Fluoroquinolones; Heart; Heart Rate; Hypoglycemia; Intermediate-Conductance Calcium-Activated Potassium Channels; Levofloxacin; Male; Mesenteric Arteries; Moxifloxacin; Ofloxacin; Quinolines; Rats; Rats, Wistar; Small-Conductance Calcium-Activated Potassium Channels; Streptozocin | 2013 |
Forehead abscess caused by Klebsiella oxytoca with undiagnosed type 2 diabetes.
Topics: Abscess; Anti-Bacterial Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Drainage; Forehead; Humans; Klebsiella Infections; Klebsiella oxytoca; Levofloxacin; Male; Middle Aged; Ofloxacin | 2012 |
A peptide based on homologous sequences of the β-barrel assembly machinery component BamD potentiates antibiotic susceptibility of Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Bacterial Outer Membrane Proteins; Blotting, Western; Colistin; Disease Models, Animal; Drug Therapy, Combination; Electrophoresis, Polyacrylamide Gel; Female; Levofloxacin; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Ofloxacin; Peptides; Pneumonia, Bacterial; Protein Binding; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome | 2012 |
Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Logistic Models; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Ofloxacin; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Remission Induction; Spain; Surveys and Questionnaires; Time Factors; Treatment Failure | 2013 |
Evaluation of antimicrobial activity of certain combinations of antibiotics against in vitro Staphylococcus epidermidis biofilms.
Topics: Biofilms; Clindamycin; Drug Combinations; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis | 2012 |
Copper(II)-fluoroquinolone complexes with anti-Trypanosoma cruzi activity and DNA binding ability.
Topics: Animals; Cattle; Copper; DNA; Electron Spin Resonance Spectroscopy; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Ofloxacin; Organometallic Compounds; Spectrophotometry, Ultraviolet; Trypanocidal Agents; Trypanosoma cruzi | 2012 |
Recombinant protective antigen anthrax vaccine improves survival when administered as a postexposure prophylaxis countermeasure with antibiotic in the New Zealand white rabbit model of inhalation anthrax.
Topics: Animals; Anthrax; Anthrax Vaccines; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antigens, Bacterial; Bacterial Toxins; Disease Models, Animal; Drug Therapy, Combination; Humans; Immunoglobulin G; Levofloxacin; Ofloxacin; Post-Exposure Prophylaxis; Rabbits; Recombinant Proteins; Respiratory Tract Infections; Survival Analysis; Treatment Outcome; Vaccination | 2012 |
In vitro prevention of Pseudomonas aeruginosa early biofilm formation with antibiotics used in cystic fibrosis patients.
Topics: Bacterial Typing Techniques; Biofilms; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Levofloxacin; Lung Diseases; Male; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2012 |
[Comparison of rifabutin- and levofloxacin-based third-line rescue therapies for Helicobacter pylori].
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors; Rifabutin; Salvage Therapy | 2012 |
Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan: results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2006-2010.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Gallbladder Diseases; Hospitalization; Humans; Levofloxacin; Liver Diseases; Microbial Sensitivity Tests; Ofloxacin; Population Surveillance; Practice Guidelines as Topic; Prevalence; Prospective Studies; Pseudomonas aeruginosa; Taiwan; Time Factors | 2012 |
Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Levofloxacin; Ofloxacin; Penicillins; Pneumococcal Vaccines; Pneumonia, Pneumococcal; Serotyping; Spain; Streptococcus pneumoniae; Vaccines, Conjugate | 2012 |
Validation studies on blood collection from the jugular vein of conscious mice.
Topics: Administration, Oral; Animal Welfare; Animals; Anti-Bacterial Agents; Blood Chemical Analysis; Blood Glucose; Exenatide; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hypoglycemic Agents; Jugular Veins; Levofloxacin; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Ofloxacin; Peptides; Phlebotomy; Venoms | 2012 |
Anaphylaxis due to intravenous levofloxacin with tolerance to garenoxacin.
Topics: Adult; Anaphylaxis; Anti-Bacterial Agents; Cross Reactions; Drug Hypersensitivity; Fluoroquinolones; Humans; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Pneumonia, Mycoplasma; Skin Tests | 2012 |
In vitro assessment of the cytotoxicity of six topical antibiotics to four cultured ocular surface cell lines.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cefmenoxime; Cell Line; Cell Survival; Conjunctiva; Cornea; Dibekacin; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Quinolines; Rabbits | 2012 |
[HPLC-MS identification of degradation products of levofloxacin].
Topics: Chromatography, High Pressure Liquid; Drug Stability; Levofloxacin; Mass Spectrometry; Ofloxacin; Photolysis | 2012 |
Treatment of tuberculosis with levofloxacin or moxifloxacin: report of 6 pediatric cases.
Topics: Adolescent; Antitubercular Agents; Aza Compounds; Child; Child, Preschool; Female; Fluoroquinolones; France; Hospitals, University; Humans; Infant; Levofloxacin; Male; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2012 |
Activity of JNJ-Q2 against Staphylococcus aureus isolated from patients with acute bacterial skin and skin-structure infection obtained during a Phase 2 clinical trial.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Staphylococcal Skin Infections; Staphylococcus aureus | 2012 |
Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin.
Topics: Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Tuberculosis, Pulmonary | 2012 |
Association of levofloxacin resistance with mortality in adult patients with invasive pneumococcal diseases: a post hoc analysis of a prospective cohort.
Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prospective Studies; Risk Factors; Streptococcus pneumoniae; Treatment Outcome | 2013 |
[Levofloxacin hepatotoxicity. Higher risk in diabetics?].
Topics: Aged, 80 and over; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Female; Humans; Levofloxacin; Liver; Male; Ofloxacin | 2011 |
Mutant prevention concentration of colistin alone and in combination with levofloxacin or tobramycin against multidrug-resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Colistin; Drug Interactions; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Selection, Genetic; Tobramycin | 2012 |
Acute renal failure caused by severe coagulopathy induced by the interaction between warfarin potassium and levofloxacin: a case report.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation Disorders; Cardiomyopathy, Dilated; Drug Interactions; Hematuria; Humans; International Normalized Ratio; Levofloxacin; Male; Ofloxacin; Shock; Urinary Tract Infections; Warfarin | 2012 |
Photodegradation of fluoroquinolones in surface water and antimicrobial activity of the photoproducts.
Topics: Anti-Infective Agents; Aza Compounds; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Photolysis; Quinolines; Tandem Mass Spectrometry | 2012 |
Evidence of in vivo prophage induction during Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Aza Compounds; Base Sequence; Ciprofloxacin; Clostridioides difficile; Clostridium Infections; DNA, Viral; Feces; Fluoroquinolones; Genetic Variation; Genome, Viral; Humans; Levofloxacin; Lysogeny; Microbial Sensitivity Tests; Mitomycin; Molecular Sequence Data; Moxifloxacin; Myoviridae; Ofloxacin; Prophages; Quinolines; Sequence Analysis, DNA; Virus Activation | 2012 |
Antibacterial and synergy of berberines with antibacterial agents against clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Berberine; Cefazolin; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Synergism; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Ofloxacin | 2012 |
[The changes of ocular bacterial isolates and in vitro antimicrobial susceptibility in the past six years].
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Eye; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus epidermidis; Tobramycin | 2012 |
Pharmacokinetic and dynamic study of levofloxacin and rifampicin in bone and joint infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Arthritis, Infectious; Body Mass Index; Discitis; Dose-Response Relationship, Drug; Female; Fracture Fixation, Internal; Gastrointestinal Diseases; Humans; Levofloxacin; Male; Middle Aged; Musculoskeletal Diseases; Ofloxacin; Osteitis; Prospective Studies; Prosthesis-Related Infections; Rifampin; Sacroiliitis; Staphylococcal Infections; Surgical Wound Infection | 2012 |
Efficacy of a therapeutic strategy for eradication of Helicobacter pylori infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Breath Tests; Clarithromycin; Comorbidity; Disease Eradication; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Proton Pump Inhibitors; Retrospective Studies; Tinidazole; Treatment Outcome; Ulcer; Young Adult | 2012 |
[Levofloxacin hepatotoxicity].
Topics: Adult; Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Bronchiectasis; Bronchitis; Ceftriaxone; Chemical and Drug Induced Liver Injury; Drug Substitution; gamma-Glutamyltransferase; Hepatomegaly; Humans; Hyperbilirubinemia; Levofloxacin; Male; Ofloxacin | 2013 |
Does levofloxacin induce hemolytic uremic syndrome in patients infected with verotoxin-producing Escherichia coli O157 infections?
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Colitis; Escherichia coli Infections; Escherichia coli O157; Female; Hemolytic-Uremic Syndrome; Humans; Japan; Levofloxacin; Male; Middle Aged; Ofloxacin; Retrospective Studies; Risk Factors; Shiga Toxins | 2012 |
A phytoanticipin derivative, sodium houttuyfonate, induces in vitro synergistic effects with levofloxacin against biofilm formation by Pseudomonas aeruginosa.
Topics: Alkanes; Anti-Bacterial Agents; Biofilms; Drug Combinations; Drug Synergism; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Sulfites | 2012 |
The effectiveness of single-dose fosfomycin as antimicrobial prophylaxis for patients undergoing transrectal ultrasound-guided biopsy of the prostate.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy, Needle; Fosfomycin; Humans; Image-Guided Biopsy; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate; Retrospective Studies; Ultrasonography, Interventional | 2012 |
Analysis of mutations in the gyrA and gyrB genes and their association with the resistance of Mycobacterium tuberculosis to levofloxacin, moxifloxacin and gatifloxacin.
Topics: Antitubercular Agents; Aza Compounds; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gene Expression Regulation, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Russia; Tuberculosis, Pulmonary | 2013 |
[Protection and mechanism of Fagopyrum cymosum on lung injury in rats with Klebsiella pneumonia].
Topics: Animals; Chemokine CXCL2; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Fagopyrum; Immunohistochemistry; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Lung; Male; Ofloxacin; Pneumonia, Bacterial; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Levofloxacin-associated panuveitis with chorioretinal lesions.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Bites and Stings; Female; Fluorescein Angiography; Glucocorticoids; Humans; Levofloxacin; Ofloxacin; Panuveitis; Prednisone; Retinal Diseases; Tomography, Optical Coherence; Visual Acuity | 2012 |
Cumulative Helicobacter pylori eradication therapy in obese patients undergoing gastric bypass surgery.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Gastric Bypass; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Middle Aged; Obesity, Morbid; Ofloxacin; Portugal; Practice Guidelines as Topic; Proton Pump Inhibitors; Risk Factors; Stomach Neoplasms; Surgical Wound Infection; Treatment Failure; Young Adult | 2013 |
A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague.
Topics: Animals; Animals, Outbred Strains; Anti-Bacterial Agents; Disease Models, Animal; Female; Flow Cytometry; Genes, Reporter; Humans; Levofloxacin; Luciferases; Mice; Microscopy, Fluorescence; Molecular Imaging; Ofloxacin; Plague; Virulence; Yersinia pestis | 2013 |
Persistence of ultrasound alterations after antibiotic treatment with levofloxacin in patients with male accessory gland infection.
Topics: Adult; Anti-Bacterial Agents; Epididymis; Epididymitis; Genital Diseases, Male; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Retrospective Studies; Seminal Vesicles; Superinfection; Ultrasonography | 2012 |
Comparison of contamination rates between preserved and preservative-free fluoroquinolone eyedrops.
Topics: Anti-Bacterial Agents; Aspergillus niger; Bacteria; Bacteriological Techniques; Benzalkonium Compounds; Candida albicans; Colony Count, Microbial; Drug Contamination; Eye Diseases; Female; Fluoroquinolones; Fungi; Gatifloxacin; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Pseudomonas aeruginosa; Staphylococcus aureus | 2013 |
The effects of levofloxacin on rabbit fibroblast-like synoviocytes in vitro.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Cell Survival; Fibroblasts; Glucuronosyltransferase; Hyaluronan Synthases; Hyaluronic Acid; Immunohistochemistry; Interleukin-1; Interleukin-6; Levofloxacin; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Microscopy, Electron, Transmission; Ofloxacin; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA; Synovial Membrane | 2012 |
Post-marketing surveillance of levofloxacin 0.5% ophthalmic solution for external ocular infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Eye Infections; Eye Infections, Bacterial; Female; Humans; Infant; Infant, Newborn; Japan; Levofloxacin; Male; Middle Aged; Ofloxacin; Ophthalmic Solutions; Product Surveillance, Postmarketing; Treatment Outcome; Young Adult | 2012 |
Aqueous chlorination of levofloxacin: kinetic and mechanistic study, transformation product identification and toxicity.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Halogenation; Kinetics; Levofloxacin; Molecular Structure; Ofloxacin; Water; Water Pollutants, Chemical; Water Purification | 2013 |
Four consecutive cases of Achilles tendon disorders associated with levofloxacin treatment in hemodialysis patients.
Topics: Achilles Tendon; Administration, Oral; Aged; Anti-Infective Agents, Urinary; Dose-Response Relationship, Drug; Humans; Kidney Failure, Chronic; Levofloxacin; Male; Middle Aged; Ofloxacin; Renal Dialysis; Retrospective Studies; Tendinopathy; Treatment Outcome; Urinary Tract Infections | 2012 |
In vitro activity and durability of a combination of an antibiofilm and an antibiotic against vascular catheter colonization.
Topics: Acetylcysteine; Anti-Infective Agents; Biofilms; Colony Count, Microbial; Drug Combinations; Equipment Contamination; Gram-Negative Bacteria; Gram-Positive Bacteria; Levofloxacin; Ofloxacin; Vascular Access Devices | 2013 |
Simultaneous determination of the combined drugs of ceftriaxone sodium, metronidazole, and levofloxacin in human urine by high-performance liquid chromatography.
Topics: Ceftriaxone; Chromatography, High Pressure Liquid; Ethylamines; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Levofloxacin; Methanol; Metronidazole; Ofloxacin; Phosphates; Potassium Compounds; Reproducibility of Results; Sensitivity and Specificity | 2012 |
Coordinate hyperproduction of SmeZ and SmeJK efflux pumps extends drug resistance in Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Ciprofloxacin; Gene Expression; Genes, MDR; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Membrane Transport Proteins; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Stenotrophomonas maltophilia; Tetracycline | 2013 |
[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical isolates obtained from 72 centers in 2010].
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterobacteriaceae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2012 |
Resonance light scattering determination of metallothioneins using levofloxacin-palladium complex as a light scattering probe.
Topics: Coordination Complexes; Humans; Hydrogen-Ion Concentration; Levofloxacin; Light; Limit of Detection; Metallothionein; Ofloxacin; Palladium; Scattering, Radiation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2013 |
[Correction of psychoemotional status in patients with chronic bacterial prostatitis].
Topics: Adult; Anti-Anxiety Agents; Anti-Infective Agents, Urinary; Biureas; Drug Therapy, Combination; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatitis; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult | 2012 |
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Hematologic Neoplasms; Humans; Hypokalemia; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Mycoses; Ofloxacin; Pyrimidines; Risk Factors; Torsades de Pointes; Triazoles; Ventricular Dysfunction, Left; Voriconazole | 2013 |
Visual compatibility of micafungin sodium and levofloxacin injections.
Topics: Anti-Bacterial Agents; Antifungal Agents; Drug Combinations; Drug Compounding; Drug Incompatibility; Drug Stability; Echinocandins; Glucose; Humans; Levofloxacin; Lipopeptides; Micafungin; Ofloxacin; Sodium Chloride | 2012 |
Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine.
Topics: Animals; Antibodies, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Immune Sera; Immunization; Immunization, Passive; Levofloxacin; Mice; Ofloxacin; Plague; Plague Vaccine; Plasminogen Activators; Rats; Recombinant Proteins; Vaccines, Synthetic; Virulence Factors; Yersinia pestis | 2013 |
Moxifloxacin as postoperative prophylaxis for Enterococcus faecalis-induced endophthalmitis after cataract surgery in aphakic rabbits.
Topics: Administration, Ophthalmic; Animals; Anti-Bacterial Agents; Aphakia, Postcataract; Aza Compounds; Disease Models, Animal; Electroretinography; Endophthalmitis; Enterococcus faecalis; Eye Infections, Bacterial; Fluoroquinolones; Gram-Positive Bacterial Infections; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Phacoemulsification; Quinolines; Rabbits; Time Factors | 2013 |
A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits.
Topics: Animals; Anti-Bacterial Agents; Ciliary Body; Colony Count, Microbial; Cytokines; Drug Delivery Systems; Drug Implants; Endophthalmitis; Eye Infections, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Real-Time Polymerase Chain Reaction; RNA, Messenger; Staphylococcal Infections; Staphylococcus epidermidis; Vitreous Body | 2013 |
Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods.
Topics: Ampicillin; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Erythromycin; Fermentation; Food Contamination; Food Microbiology; Genes, Bacterial; Gentamicins; Levofloxacin; Microbial Sensitivity Tests; Nitrofurantoin; Ofloxacin; Penicillins; Phenotype; Vancomycin | 2013 |
Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines.
Topics: Acetic Acid; Acetylation; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Chalcones; Fluconazole; Hydrazines; Levofloxacin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Ofloxacin; Pyrazoles; Spectroscopy, Fourier Transform Infrared | 2013 |
Relationship and susceptibility profile of Staphylococcus aureus infection diabetic foot ulcers with Staphylococcus aureus nasal carriage.
Topics: Adult; Aged; Anti-Bacterial Agents; Carrier State; Diabetic Foot; Female; Humans; Levofloxacin; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Nose; Ofloxacin; Rifampin; Risk Factors; Staphylococcal Infections | 2013 |
Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli.
Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Escherichia coli; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin | 2013 |
High prevalence of fluoroquinolone-resistant group B streptococci among clinical isolates in China and predominance of sequence type 19 with serotype III.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; China; Clindamycin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Humans; Levofloxacin; Middle Aged; Mutation; Ofloxacin; Prevalence; Serotyping; Streptococcal Infections; Streptococcus agalactiae; Tetracycline | 2013 |
Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Clarithromycin; DNA Gyrase; Drug Resistance, Bacterial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Mutation; Ofloxacin; RNA, Ribosomal, 23S; Senegal; Tetracycline; Young Adult | 2013 |
The mechanisms of insulin secretion and calcium signaling in pancreatic β-cells exposed to fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Calcium Signaling; Cell Line; Cricetinae; Fluoroquinolones; Gatifloxacin; Insulin; Insulin Secretion; Insulin-Secreting Cells; Levofloxacin; Ofloxacin; Tolbutamide | 2013 |
Synthesis and antibacterial evaluation of typharin analog: 6,8-dihydroxy-7-methyl-3-styryl-3,4-dihydroisocoumarin.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Isocoumarins; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Ofloxacin; Rhizome; Typhaceae | 2013 |
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node | 2013 |
CD30+ lymphomatoid drug reactions.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amines; Amlodipine; Anti-Bacterial Agents; Anticonvulsants; Biomarkers; Biopsy; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Eruptions; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Ki-1 Antigen; Levofloxacin; Lymphocytes; Lymphoproliferative Disorders; Male; Metoprolol; Middle Aged; Ofloxacin; Predictive Value of Tests; Pseudolymphoma; Selective Serotonin Reuptake Inhibitors; Sertraline; Skin | 2013 |
Antimicrobial susceptibility of stenotrophomonas maltophilia isolates from Korea, and the activity of antimicrobial combinations against the isolates.
Topics: Anti-Infective Agents; Gram-Negative Bacterial Infections; Hospitals, University; Humans; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Republic of Korea; Stenotrophomonas maltophilia; Trimethoprim, Sulfamethoxazole Drug Combination | 2013 |
Bacillus anthracis protective antigen kinetics in inhalation spore-challenged untreated or levofloxacin/ raxibacumab-treated New Zealand white rabbits.
Topics: Adjuvants, Immunologic; Administration, Inhalation; Animals; Anthrax; Anthrax Vaccines; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Disease Models, Animal; Female; Kinetics; Levofloxacin; Male; Ofloxacin; Rabbits; Spores, Bacterial; Survival Analysis | 2013 |
Tamsulosin alters levofloxacin pharmacokinetics in prostates derived from rats with acute bacterial prostatitis.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Anti-Bacterial Agents; Drug Interactions; Escherichia coli Infections; Kidney; Levofloxacin; Liver; Male; Ofloxacin; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamsulosin | 2013 |
Comparative antibacterial effects of moxifloxacin and levofloxacin on Streptococcus pneumoniae strains with defined mechanisms of resistance: impact of bacterial inoculum.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Load; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Models, Theoretical; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Selection, Genetic; Streptococcus pneumoniae | 2013 |
[The outcome of a survey on the use of levofloxacin for the treatment of tuberculosis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Data Collection; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis | 2012 |
Rapid preparation of molecularly imprinted polymer by frontal polymerization.
Topics: Adsorption; Chemistry Techniques, Synthetic; Levofloxacin; Molecular Imprinting; Ofloxacin; Polymers; Porosity; Thermogravimetry | 2013 |
[Bifocal Buruli ulcer: multiple cephalic lesions after initiation of medical treatment].
Topics: Anti-Bacterial Agents; Buruli Ulcer; Child, Preschool; Chin; Cicatrix; Cote d'Ivoire; Drug Therapy, Combination; Endemic Diseases; Facial Dermatoses; Female; Humans; Leg; Levofloxacin; Mycobacterium ulcerans; Ofloxacin; Rifampin; Scalp Dermatoses; Time Factors | 2013 |
Antimicrobial susceptibilities of clinical isolates of HACEK organisms.
Topics: Anti-Bacterial Agents; Ceftriaxone; Gram-Negative Bacteria; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2013 |
Interactions between new quinolone antibacterials and diagnostic drug containing manganese.
Topics: Algorithms; Anti-Bacterial Agents; Chelating Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Interactions; Levofloxacin; Manganese Compounds; Ofloxacin; Quinolones | 2013 |
Comparative study on resistant pattern of clinical isolates against levofloxacin and cefepime.
Topics: Bacteria; Cefepime; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Ofloxacin | 2013 |
Susceptibility testing of extensively drug-resistant and pre-extensively drug-resistant Mycobacterium tuberculosis against levofloxacin, linezolid, and amoxicillin-clavulanate.
Topics: Acetamides; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Pakistan; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2013 |
Education and imaging. Gastrointestinal: colonic mucosa-associated lymphoid tissue lymphoma regressed by levofloxacin.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Colonic Neoplasms; Colonoscopy; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Endosonography; Female; Helicobacter Infections; Helicobacter pylori; Humans; Intestinal Mucosa; Lansoprazole; Levofloxacin; Lymphoma, B-Cell, Marginal Zone; Multimodal Imaging; Occult Blood; Ofloxacin; Polymerase Chain Reaction; Positron-Emission Tomography; Tomography, X-Ray Computed | 2013 |
Synthesis, in vitro antimycobacterial and antibacterial evaluation of IMB-070593 derivatives containing a substituted benzyloxime moiety.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Levofloxacin; Magnetic Resonance Spectroscopy; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oximes; Piperidines; Staphylococcus aureus | 2013 |
[Bactericidal effect of levofloxacin injection in combination with meropenem against Pseudomonas aeruginosa using an in vitro simulation model with a hollow fiber system].
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Thienamycins | 2012 |
[Efficacy and safety of levofloxacin to non-gonorrheal urethritis].
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Humans; Levofloxacin; Male; Middle Aged; Mycoplasma genitalium; Mycoplasma Infections; Ofloxacin; Urethritis | 2012 |
Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Levofloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Treatment Outcome; Tuberculosis | 2013 |
Levofloxacin-induced seizures in a patient without predisposing risk factors: the impact of pharmacogenetics.
Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Humans; Levofloxacin; Neoplasm Proteins; Ofloxacin; Polymorphism, Single Nucleotide; Risk Factors; Seizures | 2013 |
Treatment of tularemia in patient with chronic graft-versus-host disease.
Topics: Anti-Bacterial Agents; Chronic Disease; Doxycycline; Francisella tularensis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Tularemia | 2013 |
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2013 |
Pelvic inflammatory disease in the adolescent: understanding diagnosis and treatment as a health care provider.
Topics: Adolescent; Anti-Bacterial Agents; Arkansas; Ceftriaxone; Centers for Disease Control and Prevention, U.S.; Child; Diagnosis, Differential; Diagnostic Errors; Doxycycline; Ethnicity; Female; Guideline Adherence; Humans; International Classification of Diseases; Levofloxacin; Metronidazole; Ofloxacin; Outpatient Clinics, Hospital; Pain; Pelvic Inflammatory Disease; Practice Guidelines as Topic; Recurrence; Retrospective Studies; Sexually Transmitted Diseases; Symptom Assessment; United States; Uterine Cervicitis; Young Adult | 2013 |
Effectiveness of single-dose fosfomycin as antimicrobial prophylaxis in transrectal ultrasound-guided biopsy of the prostate.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Fosfomycin; Humans; Levofloxacin; Male; Ofloxacin; Prostate; Ultrasonography | 2013 |
Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Microscopy, Confocal; Microscopy, Electron, Scanning; Norfloxacin; Ofloxacin; Streptococcal Infections; Streptococcus pyogenes; Virulence | 2013 |
Assessment of the combination of doripenem plus a fluoroquinolone against non-susceptible Acinetobacter baumannii isolates from nosocomial pneumonia patients.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Carbapenems; Ciprofloxacin; Doripenem; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Female; Levofloxacin; Mice; Ofloxacin; Pneumonia, Ventilator-Associated; Random Allocation; Survival Analysis | 2013 |
Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.
Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Case-Control Studies; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Tuberculosis | 2013 |
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis | 2013 |
Severe hypoglycemia associated with levofloxacin in a healthy older woman.
Topics: Administration, Oral; Aged, 80 and over; Anti-Bacterial Agents; Blood Glucose; Female; Humans; Hypoglycemia; Levofloxacin; Ofloxacin; Phlebitis | 2013 |
Prevalence and molecular characterization of fluoroquinolone-resistant Mycobacterium tuberculosis isolates in China.
Topics: Antitubercular Agents; China; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prevalence | 2014 |
Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Amikacin; Antitubercular Agents; Cycloserine; Ethionamide; Female; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Sputum; Tanzania; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Novel agent for Helicobacter pylori infection management.
Topics: Animals; Anti-Bacterial Agents; Escherichia coli; Female; Galactosylceramides; Gastric Mucosa; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation; Intestines; Levofloxacin; Lymphocyte Activation; Male; Natural Killer T-Cells; Ofloxacin; Sphingomonas; Stomach | 2013 |
Co-infection with Orientia tsutsugamushi and Mycoplasma pneumoniae in a traveler.
Topics: Humans; Leptospirosis; Levofloxacin; Male; Ofloxacin; Penicillins; Protein C; Respiratory Insufficiency; Scrub Typhus; Shock, Septic | 2015 |
Fluoroquinolone susceptibility testing of Salmonella enterica: detection of acquired resistance and selection of zone diameter breakpoints for levofloxacin and ofloxacin.
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Salmonella enterica; Salmonella Infections | 2014 |
Re: the effectiveness of single-dose fosfomycin as antimicrobial prophylaxis for patients undergoing transrectal ultrasound-guided biopsy of the prostate.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Fosfomycin; Humans; Levofloxacin; Male; Ofloxacin; Prostate; Ultrasonography | 2014 |
Pharmacokinetics of ofloxacin and levofloxacin for prevention and treatment of multidrug-resistant tuberculosis in children.
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Female; Humans; Infant; Levofloxacin; Male; Ofloxacin; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2014 |
Inhibitory effect of ciprofloxacin on β-glucuronidase-mediated deconjugation of mycophenolic acid glucuronide.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Enterohepatic Circulation; Glucuronidase; Glucuronides; Immunosuppressive Agents; In Vitro Techniques; Inhibitory Concentration 50; Levofloxacin; Mycophenolic Acid; Ofloxacin; Phenolphthaleins; Time Factors | 2014 |
[Efficacy and safety of levofloxacin in patients with nursing and healthcare-associated pneumonia].
Topics: Anti-Bacterial Agents; Cross Infection; Female; Humans; Japan; Levofloxacin; Male; Ofloxacin; Pneumonia; Prospective Studies | 2014 |
Molecular modeling application on hapten epitope prediction: an enantioselective immunoassay for ofloxacin optical isomers.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibody Specificity; Epitopes; Female; Haptens; Immunoassay; Isomerism; Levofloxacin; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Ofloxacin; Quantitative Structure-Activity Relationship; Stereoisomerism | 2014 |
The effect of some fluoroquinolone family members on biospeciation of copper(II), nickel(II) and zinc(II) ions in human plasma.
Topics: Ciprofloxacin; Coordination Complexes; Copper; Fluoroquinolones; Humans; Ions; Levofloxacin; Moxifloxacin; Nickel; Ofloxacin; Zinc | 2014 |
Fluoroquinolone use delays tuberculosis treatment despite immediate mycobacteriology study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Community-Acquired Infections; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Linear Models; Longitudinal Studies; Male; Middle Aged; Moxifloxacin; Multivariate Analysis; Mycobacterium tuberculosis; Ofloxacin; Pneumonia, Bacterial; Taiwan; Tuberculosis, Pulmonary; Young Adult | 2015 |
Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica.
Topics: Anti-Bacterial Agents; Bacteremia; Base Sequence; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Nalidixic Acid; Ofloxacin; Pefloxacin; Salmonella enterica; Salmonella Infections; Sequence Analysis, DNA | 2015 |
Effect of C-5 position on the photochemical properties and phototoxicity of antofloxacin and levofloxacin: A stable and transient study.
Topics: Electron Transport; Electrophoresis, Polyacrylamide Gel; Energy Transfer; Fluoroquinolones; Lasers, Solid-State; Levofloxacin; Ofloxacin; Photolysis; Quantum Theory | 2016 |
Role of gyrB Mutations in Pre-extensively and Extensively Drug-Resistant Tuberculosis in Thai Clinical Isolates.
Topics: Aminopyridines; Antitubercular Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Gatifloxacin; Gene Expression; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Thailand; Tuberculosis, Pulmonary | 2016 |
Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin.
Topics: Antitubercular Agents; China; DNA Gyrase; Drug Dosage Calculations; Drug Resistance, Bacterial; Fluoroquinolones; Gene Expression; Genotype; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Pulmonary | 2016 |
Letter: levofloxacin resistance - a challenge for the treatment of Helicobacter pylori infection.
Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Ofloxacin | 2017 |
Kounis Syndrome After Intake of Levofloxacin: Increasing Incidence of Hypersensitivity to Fluoroquinolones.
Topics: Anaphylaxis; Anti-Bacterial Agents; Fluoroquinolones; Humans; Incidence; Levofloxacin; Ofloxacin | 2017 |
Baseline resistance and cross-resistance among fluoroquinolones in multidrug-resistant Mycobacterium tuberculosis isolates at a national reference laboratory in India.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Humans; India; Levofloxacin; Male; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Prospective Studies; Tuberculosis, Multidrug-Resistant; Young Adult | 2018 |
Enantioselective degradation of ofloxacin and levofloxacin by the bacterial strains Labrys portucalensis F11 and Rhodococcus sp. FP1.
Topics: Alphaproteobacteria; Anti-Bacterial Agents; Biodegradation, Environmental; Chromatography, Liquid; Levofloxacin; Ofloxacin; Rhodococcus; Stereoisomerism; Tandem Mass Spectrometry | 2018 |
STUDY OF OFLOXACIN ENANTIOMERS DISSOLUTION FROM SELECTED SOLID DOSAGE FORMS USING HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS METHOD.
Topics: Anti-Infective Agents; Calibration; Drug Compounding; Drug Liberation; Electrophoresis, Capillary; Isomerism; Kinetics; Levofloxacin; Limit of Detection; Models, Chemical; Models, Statistical; Ofloxacin; Reference Standards; Solubility; Tablets; Technology, Pharmaceutical | 2017 |
When antibiotics turn toxic.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antioxidants; Ciprofloxacin; Female; Fluoroquinolones; Genetic Testing; Humans; Inactivation, Metabolic; Levofloxacin; Male; Mice; Mitochondria; Naphthyridines; Ofloxacin; Oxidative Stress; Syndrome; Topoisomerase II Inhibitors; United States; United States Food and Drug Administration | 2018 |
Anaphylactic shock secondary to oral ofloxacin administration with cross-reactivity to levofloxacin and ciprofloxacin.
Topics: Administration, Oral; Adolescent; Anaphylaxis; Ciprofloxacin; Cross Reactions; Drug Hypersensitivity; Escherichia coli Infections; Female; Humans; Levofloxacin; Ofloxacin; Skin Tests; Urinary Tract Infections | 2018 |
Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Case-Control Studies; Ciprofloxacin; Female; Fluoroquinolones; Humans; Incidence; Levofloxacin; Male; Middle Aged; Moxifloxacin; Norfloxacin; Ofloxacin; Peripheral Nervous System Diseases; Risk Factors; Sex Factors; United Kingdom | 2019 |
Fluoroquinolones in Drug-Resistant Tuberculosis: Culture Conversion and Pharmacokinetic/Pharmacodynamic Target Attainment To Guide Dose Selection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Moxifloxacin; Ofloxacin; Retrospective Studies; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2019 |
Using Mycobacterium tuberculosis Single-Nucleotide Polymorphisms To Predict Fluoroquinolone Treatment Response.
Topics: Antitubercular Agents; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Single Nucleotide | 2019 |
Levofloxacin-Associated Mania: A Case Report.
Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Mania; Ofloxacin | 2020 |
Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran.
Topics: Antitubercular Agents; Codon; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Genotype; Humans; Iran; Levofloxacin; Male; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Multidrug-Resistant | 2020 |
Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.
Topics: Antitubercular Agents; China; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pharmaceutical Preparations; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2021 |
Acceptability of levofloxacin, moxifloxacin and linezolid among children and adolescents treated for TB.
Topics: Adolescent; Anti-Bacterial Agents; Aza Compounds; Child; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Tuberculosis | 2020 |
Quantification of persister formation of Escherichia coli leveraging electronic cell counting and semi-mechanistic pharmacokinetic/pharmacodynamic modelling.
Topics: Anti-Bacterial Agents; Electronics; Escherichia coli; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2021 |
A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Adverse Drug Reaction Reporting Systems; Arthralgia; Ciprofloxacin; Connective Tissue Diseases; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Musculoskeletal Diseases; Myalgia; Norfloxacin; Ofloxacin; Pain; Risk Factors; Tendinopathy; Tendons; Young Adult | 2021 |
Development of a dosing-adjustment tool for fluoroquinolones in osteoarticular infections: The Fluo-pop study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Diseases, Infectious; Female; Fluoroquinolones; Humans; Joint Diseases; Levofloxacin; Male; Middle Aged; Models, Biological; Monte Carlo Method; Ofloxacin; Prospective Studies; Staphylococcus; Young Adult | 2021 |
Accumulation of chiral pharmaceuticals (ofloxacin or levofloxacin) onto polyethylene microplastics from aqueous solutions.
Topics: Adsorption; Levofloxacin; Microplastics; Ofloxacin; Pharmaceutical Preparations; Plastics; Polyethylene; Water Pollutants, Chemical | 2022 |
Fractionation of levofloxacin and ofloxacin during their transport in NOM-goethite: Batch and column studies.
Topics: Adsorption; Humic Substances; Iron Compounds; Levofloxacin; Ofloxacin | 2023 |
In-Class Cross-Reactivity among Hospitalized Patients with Hypersensitivity Reactions to Fluoroquinolones.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Hypersensitivity; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines | 2023 |
Study effect and mechanism of ofloxacin and levofloxacin on development of Rana nigromaculata tadpoles based on the hypothalamus-pituitary-thyroid axis.
Topics: Animals; Anti-Bacterial Agents; Hypothalamus; Larva; Levofloxacin; Molecular Docking Simulation; Ofloxacin; Ranidae; Thyroid Gland; Thyrotropin | 2023 |