ofloxacin has been researched along with isoniazid in 150 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (4.00) | 18.7374 |
1990's | 22 (14.67) | 18.2507 |
2000's | 33 (22.00) | 29.6817 |
2010's | 81 (54.00) | 24.3611 |
2020's | 8 (5.33) | 2.80 |
Authors | Studies |
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Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M | 1 |
Govender, K; Govender, P; Govender, T; Kruger, HG; Maguire, GE; Muthusamy, K; Onajole, OK; Pillay, M; van Helden, PD; Wiid, I | 1 |
Banerjee, D; Bhat, P; Dinakaran, M; Gadhwal, S; Sriram, D; Yogeeswari, P | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ | 1 |
Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Senadeera, SP; Sureram, S | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Chestnova, RV; Fattakhov, SG; Mingaleev, DN; Reznik, VS; Saifina, LF; Shulaeva, MM; Valijev, RSh; Voloshina, AD | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T | 1 |
Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH | 1 |
Achar, V; Arora, U; Awasthy, D; Bharath, S; Bheemarao, U; Chinnapattu, M; Coulson, M; de Sousa, SM; Ganguly, S; Gaonkar, S; Ghosh, A; Hameed P, S; Hoffner, S; Humnabadkar, V; Kaur, P; Kumar K N, M; Kumar, CN; Madhavapeddi, P; Manjrekar, P; Menasinakai, S; Mukherjee, K; Nandishaiah, R; Narayan, C; Panduga, V; Patil, V; Puttur, J; Raichurkar, A; Ramya, VK; Reddy, J; Rudrapatana, S; Sambandamurthy, VK; Shanbhag, G; Sharma, S; Sharma, U; Shinde, V; Solapure, S; Waterson, D; Werngren, J | 1 |
Ambady, A; Guptha, S; Hegde, N; Hosagrahara, VP; Humnabadkar, V; Kaur, P; Mahadevaswamy, J; Nagalapur, K; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, S; Ramachandran, V; Rudrapatna, SS; Sambandamurthy, VK; Sharma, S; Shirude, PS | 1 |
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P | 1 |
Babu, KS; Jeankumar, VU; Reddy, KI; Renuka, J; Shravan, M; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P | 1 |
Devi, PB; Jeankumar, VU; Pedgaonkar, GS; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P | 2 |
Babu, KS; Chuppala, A; Jeankumar, VU; Reddy, KI; Renuka, J; Sree, KS; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P | 1 |
Aree, T; Ganihigama, DU; Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Sangher, S; Sureram, S | 1 |
Bowornwiriyapan, K; Daengrot, C; Phongpaichit, S; Rukachaisirikul, V; Sakayaroj, J; Tansakul, C; Thongpanchang, T | 1 |
Renuka, J; Samala, G; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P | 1 |
Dixit, PP; Thore, SN | 1 |
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Burgart, YV; Krasnykh, OP; Kravchenko, MA; Saloutin, VI; Shchegol'kov, EV; Shchur, IV; Solodnikov, SY | 1 |
Bekker, OB; Charushin, VN; Danilenko, VN; Gruzdev, DA; Krasnov, VP; Kravchenko, MA; Levit, GL; Matveeva, TV; Musiyak, VV; Nizova, IA; Skornyakov, SN; Vigorov, AY | 1 |
Bowornwiriyapan, K; Duangjai, A; Muanprasat, C; Phainuphong, P; Phongpaichit, S; Rukachaisirikul, V; Saithong, S; Sakayaroj, J; Srimaroeng, C | 1 |
Baskakova, SA; Charushin, VN; Chupakhin, ON; Kravchenko, MA; Rusinov, GL; Skornyakov, SN; Verbitskiy, EV | 1 |
Janupally, R; Jeankumar, VU; Reshma, RS; Saxena, S; Sriram, D; Vats, R; Yogeeswari, P | 1 |
Chaudhari, K; Jain, P; Patel, HM; Surana, S | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K | 1 |
Avalos-Alanís, FG; Carranza-Rosales, P; Guzmán-Delgado, NE; Hernández-Fernández, E; Hernández-Fernández, J; López-Cortina, S; Morales-Vargas, A; Ordóñez, M; Santiago-Mauricio, MG; Velázquez-Moreno, VM | 1 |
Mahajan, SS; Saharan, VD | 1 |
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H | 1 |
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ | 1 |
Alluri, KK; Gottapu, S; Reshma, RS; Sriram, D; Suraparaju, R | 1 |
Gao, YM; Liang, J; Liu, ZY; Qian, L; Tang, YX; Yan, M; Zhang, NN; Zhang, TY | 1 |
Bishai, WR; Duan, G; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
Bera, S; Mondal, D | 1 |
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K | 1 |
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR | 1 |
Bishai, WR; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Wang, SS; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
Kwan, SY; Lee, J; Wong, PC; Yew, WW | 1 |
Hara, K; Kaku, M; Koga, H; Kohno, S; Maesaki, S | 1 |
Alberte, A; Estébanez, MJ; Martínez-Sagarra, JM; Pascual, PP | 1 |
Chau, PY; Khin, MA; Kwan, SY; Ma, WK; Yew, WW | 1 |
Tsukamura, M; Yamori, S | 1 |
Heap, BJ | 1 |
Berlin, OG; Bruckner, DA; Young, LS | 1 |
Casal, M; González, J; Gutierrez, J; Ruiz, P | 1 |
Arai, R; Furuse, K; Kawahara, M; Kita, N; Sakatani, M | 1 |
Saito, H; Tsukamura, M; Yasuda, Y; Yoshii, S | 1 |
Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C | 1 |
Mühlberger, F; Nasbimana, J; Nturanye, F; Portaels, F | 1 |
Aleksandrova, AE; Vinogradova, TI | 1 |
Herbert, D; Kubendiran, G; Mitchison, DA; Paramasivan, CN; Prabhakar, R; Venkatesan, P | 1 |
Hadiarto, M; Hudoyo, A; Tjandra, YA | 1 |
Furukawa, T; Komachi, H; Nagai, R; Saito, Y; Takewaki, S; Uchihara, T | 1 |
Hirose, T; Ikeda, T; Iwanaga, T; Kishikawa, R; Nishima, S; Tsurutani, H; Yokota, K | 1 |
Kumar, D; Srivastava, BS; Srivastava, R; Subramaniam, P | 1 |
Padeĭskaia, EN | 1 |
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE | 1 |
Collins, LA; Franzblau, SG; Torrero, MN | 1 |
Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE | 1 |
Liu, HX; Yu, CL; Yuan, ZB; Zhang, SS | 1 |
Donald, PR; Githui, W; Kam, KM; Lam, CW; Mitchison, DA; Odhiambo, J; Paramasivan, CN; Sirgel, FA; Sole, KM; Tam, CM; Umapathy, KC | 1 |
Bajaksouzian, S; Jacobs, MR; Joloba, ML | 1 |
Mitchison, D; Sirgel, F; Venter, A | 1 |
Cheon, SH; Dietze, R; Ellner, JJ; Hise, AG; Landen, K; Palaci, M; Phillips, M; Ribeiro, FC; Song, HY; Vinhas, S; Wallis, RS | 1 |
Liu, HX; Wu, YJ; Yu, CL; Zhang, SS | 1 |
Bowersox, J | 1 |
Ataç, G; Kapakli, N; Karasulu, L; Kir, A; Ozmen, I; Sevim, T; Tahaoğlu, K; Törün, T | 1 |
Duan, L; Lin, Y; Wu, Q | 1 |
Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE | 1 |
Bogadel'nikova, IV; Kunichan, AD; Semenova, OV; Sokolova, GB | 1 |
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA | 1 |
Kunichan, AD; Litovchenko, KV; Sokolova, GB; Tsybanev, AA | 1 |
Li, SM; Xing, BC; Zheng, XM | 1 |
Gurumurthy, P; Kumar, AK | 1 |
Boibieux, A; Chidiac, C; Issartel, B; Petiot, P; Peyramond, D; Rabar, D | 1 |
Bose, M; Dam, T; Isa, M | 1 |
Hoeppner, VH; Jones, W; Marciniuk, DD; Ward, HA | 1 |
Bhusal, Y; Shiohira, CM; Yamane, N | 1 |
Farnia, P; Khoshnood, K; Mansoori, SD; Masjedi, H; Masjedi, MR; Mirsaeidi, SM; Mohammadi, F; Pooramiri, MV; Rowhani-Rahbar, A; Tabarsi, P; Velayati, AA; Zahirifard, S | 1 |
Cappelletty, DM | 1 |
Otomo, K; Shi, R; Sugawara, I; Zhang, G; Zhang, J | 1 |
Allen, J; Coleman, DJ; Davies, GR; Fourie, B; Kanyok, T; Levin, J; Lienhardt, C; Mitchison, DA; Mthiyane, T; Reddy, C; Rustomjee, R; Sirgel, FA; Sturm, AW | 1 |
Martínez, E; Nam-Cha, S; Puerta, A; Salinas, A | 1 |
Chen, YH; Eng, HL; Huang, CK; Lai, CH; Lin, HF; Lin, HH; Lin, JN | 1 |
Chadha, S; Chandrasekar, V; Chauhan, LS; Dave, PV; Dewan, P; Nalini, S; Narayanan, PR; Paramasivan, CN; Parmar, M; Ramachandran, R; Sahu, S; Sanghvi, AS; Wares, F | 1 |
Ang, C; Bravo, LT; Destura, RV; Gordon, SM; Hall, GS; Mendoza, M; Procop, GW; Shrestha, NK; Tuohy, MJ | 1 |
Agarwal, A; Arora, A; Kumar, S | 1 |
Cai, HL; Chen, YC; Fang, PF; Gao, W; Li, HD; Liu, YP; Tan, QY; Xu, P; Zhang, F; Zhang, WY; Zhu, RH | 1 |
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A | 1 |
Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM | 1 |
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA | 1 |
Connolly, C; Friedland, G; Gandhi, N; Moodley, P; Shah, NS; Sturm, AW; Tayob, N; Zetola, N | 1 |
Cremades, R; Galiana, A; García-Pachón, E; López, P; Rodríguez, JC; Royo, G; Ruiz-García, M | 1 |
Hsueh, PR; Huang, YT; Lai, CC; Liao, CH; Tan, CK | 1 |
Cho, EH; Jeon, CY; Kang, H; Kim, H; Kim, M; Murray, MB; Park, YK | 1 |
Chen, X; Gilbert, GL; Kong, F; Li, C; Wang, Q; Zhang, J | 1 |
Badri, T; Belghith, I; Benmously, R; Mokhtar, I; Zaiem, A | 1 |
de Rijk, P; Fissette, K; Martin, A; Palomino, JC; Ramos, E | 1 |
Eisenberg, N; Govender, K; Hartman, TE; Hatfull, GF; Jacobs, WR; Jain, P; Kriakov, J; Larsen, MH; Makume, M; Moodley, P; O'Donnell, MR; Sturm, AW; Thaler, DS | 1 |
González-Martín, J; Martínez, JA; Rey-Jurado, E; Tudó, G | 1 |
Hassan, G; Kant, S; Parengal, J; Saheer, S | 1 |
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y | 1 |
Bergmann, JF; Cambau, E; Evans, J; Hoang-Nguyen, DT; Lloret-Linares, C; Lopes, A; Mouly, S; Raskine, L; Sellier, P | 1 |
Banavaliker, JN; Behera, D; Bhatnagar, AK; Hanif, M; Kaushik, A; Makkar, N; Pande, JN; Porwal, C; Singh, UB; Singla, R | 1 |
Choe, KH; Chung, GT; Hwang, SC; Jnawali, HN; Kim, H; Lee, YS; Park, YK; Ryoo, S | 1 |
Chikamatsu, K; Fujita, A; Matsumoto, T; Mitarai, S; Mizuno, K; Ogata, H; Saito, T; Suetake, T; Suzuki, K; Toyota, E | 1 |
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A | 1 |
Cox, H; Fielding, K; Finlayson, H; Godfrey-Faussett, P; Hesseling, AC; Hughes, J; Schaaf, HS; Seddon, JA | 1 |
Chen, Y; Li, GL; Liu, HC; Liu, ZG; Sun, Q; Wan, KL; Wu, XC; Xia, Q; Zhao, LL; Zhao, XQ | 1 |
Alkhovik, OI; Cherednichenko, AG; Dymova, MA; Filipenko, ML; Khrapov, EA; Petrenko, TI | 1 |
Choi, SB; Jo, KW; Jung, H; Kang, MR; Lee, YS; Shim, TS | 1 |
Augustynowicz-Kopeć, E; Bakuła, Z; Bielecki, J; Jagielski, T; Kamiński, M; Napiórkowska, A; Zwolska, Z | 1 |
Balagaddé, FK; Luthuli, BB; Purdy, GE | 1 |
Chen, Y; Liu, HC; Liu, ZG; Sun, Q; Wan, KL; Zhao, B; Zhao, LL; Zhao, XQ | 1 |
Ardizzoni, E; Aspindzelashvili, R; Bastard, M; de Jong, BC; Goginashvili, L; Kotrikadze, T; Mulders, W; Pangtey, H; Rigouts, L; Varaine, F | 1 |
Deng, YT; Huang, ZK; Li, JM; Luo, Q; Qing, C; Xiong, GL | 1 |
Chen, ST; Huang, HR; Jiang, GL; Ma, YF; Wang, GR; Yu, X | 1 |
Abbas, M; Ehtisham-Ul-Haque, S; Javed, I; Javed, MT; Mahmood, Z; Riaz, M; Shahid, M | 1 |
Dixit, P; Jain, A; Jaiswal, I; Singh, M; Singh, P; Singhal, P | 1 |
Campanerut-Sá, PAZ; Cardoso, RF; Ghiraldi-Lopes, LD; Meneguello, JE; Pavan, FR; Scodro, RBL; Siqueira, VLD; Svidzinski, TIE; Teixeira, JJV | 1 |
Alene, KA; Bai, L; Clements, ACA; Gray, DJ; McBryde, ES; Viney, K; Xu, Z; Yang, K; Yi, H | 1 |
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR | 1 |
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T | 1 |
Antiabong, JF; Lekalakala, RM; Malinga, LA; Maningi, NE; Mbelle, NM | 1 |
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM | 1 |
Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G | 1 |
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F | 1 |
Jafari, R; Moghim, S; Nasr Esfahani, B; Safari, M; Salehi, M | 1 |
Ji, Y; Li, Z; Liu, Q; Martinez, L; Qiu, B; Song, H; Wang, J; Yang, D | 1 |
Guo, Y; Liu, H; Sha, W; Shen, H; Shen, X; Tan, G; Wu, X; Wu, Z; Yang, J; Yu, F | 1 |
Guo, Y; Huang, C; Sha, W; Tan, G; Wu, X; Yang, J; Yu, F | 1 |
Adhikary, A; Biswal, S; Chatterjee, D; Ghosh, AS | 1 |
8 review(s) available for ofloxacin and isoniazid
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Mycobacterium Tuberculosis (MTB) GyrB inhibitors: An attractive approach for developing novel drugs against TB.
Topics: Antitubercular Agents; Clinical Trials as Topic; DNA Gyrase; Drug Discovery; Humans; Mycobacterium tuberculosis; Topoisomerase II Inhibitors | 2016 |
Fluoroquinolone derivatives and their anti-tubercular activities.
Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis | 2021 |
[Value of ciprofloxacin in the therapy of tuberculosis and other mycobacterioses].
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections; Ofloxacin; Rifampin | 1997 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
Systematic review on the proteomic profile of Mycobacterium tuberculosis exposed to drugs.
Topics: Anti-Bacterial Agents; Electrophoresis, Gel, Two-Dimensional; Fluoroquinolones; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Proteome; Proteomics; Streptomycin | 2017 |
11 trial(s) available for ofloxacin and isoniazid
Article | Year |
---|---|
A controlled study of rifabutin and an uncontrolled study of ofloxacin in the retreatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin and rifampicin. Hong Kong Chest Service/British Medical Research Council.
Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Sputum; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary | 1992 |
Prospective comparative study of ofloxacin or ethambutol for the treatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Combinations; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Prospective Studies; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1992 |
Treatment of multidrug-resistant tuberculosis in Indonesia.
Topics: Adult; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nausea; Ofloxacin; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant | 1996 |
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis | 1997 |
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
A multicentre study of the early bactericidal activity of anti-tuberculosis drugs.
Topics: Adult; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Hong Kong; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; South Africa; Sputum; Tuberculosis, Pulmonary | 2000 |
[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Clinical Protocols; Drug Therapy, Combination; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2004 |
Disposition of uric acid upon administration of ofloxacin alone and in combination with other anti-tuberculosis drugs.
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Humans; Isoniazid; Male; Ofloxacin; Pyrazinamide; Rifampin; Uric Acid | 2004 |
Treatment of multiple drug-resistant tuberculosis (MDR-TB) in Iran.
Topics: Adolescent; Adult; Aged; Amikacin; Antitubercular Agents; Cycloserine; Drug Therapy, Combination; Female; Humans; Iran; Isoniazid; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2005 |
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Nonlinear Dynamics; Ofloxacin; Pyrazinamide; Quinolines; Rifampin; Sputum | 2008 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult | 2011 |
131 other study(ies) available for ofloxacin and isoniazid
Article | Year |
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Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation.
Topics: Animals; Antitubercular Agents; Combinatorial Chemistry Techniques; DNA Gyrase; Enzyme Inhibitors; Fluoroquinolones; Gatifloxacin; Lung; Mice; Molecular Structure; Mycobacterium tuberculosis; Ofloxacin; Spleen; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis | 2009 |
Pentacyclo-undecane derived cyclic tetra-amines: synthesis and evaluation as potent anti-tuberculosis agents.
Topics: Alkanes; Animals; Antitubercular Agents; Cattle; Cell Line; Cell Survival; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Prenylation | 2009 |
Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno[3,2-c]pyridin-3-yl derivatives.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Microbial Sensitivity Tests; Pyridines; Vero Cells | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin | 2010 |
Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis.
Topics: Alkaloids; Antitubercular Agents; Benzylisoquinolines; Drug Resistance, Multiple, Bacterial; Humans; Magnetic Resonance Spectroscopy; Menispermaceae; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Plant Extracts; Plant Roots; Tuberculosis, Multidrug-Resistant | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and antimycobacterial activity of novel 1,3-dimethylisocyanurate derivatives.
Topics: Amides; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rats; Structure-Activity Relationship; Sulfonic Acids; Triazines | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells | 2012 |
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells | 2013 |
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
Topics: Acute Disease; Administration, Oral; Animals; Antitubercular Agents; Bacterial Proteins; Biological Availability; Chronic Disease; DNA Gyrase; Drug Resistance, Bacterial; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Macrophages; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Piperidines; Protein Subunits; Rats; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tuberculosis, Pulmonary | 2014 |
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pyrazoles; Pyridones; Structure-Activity Relationship | 2014 |
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2014 |
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Benzofurans; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2014 |
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis.
Topics: Acetamides; Animals; Bacterial Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Quinazolines; Structure-Activity Relationship; Tuberculosis | 2014 |
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Cell Line; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Structure-Activity Relationship; Tuberculosis | 2014 |
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.
Topics: Animals; Antitubercular Agents; Benzofurans; Benzothiazoles; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2014 |
Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Biological Products; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Quinolines; Structure-Activity Relationship | 2015 |
Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138.
Topics: Animals; Antimalarials; Antineoplastic Agents; Biphenyl Compounds; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Penicillium; Plasmodium falciparum; Sesquiterpenes; Soil Microbiology; Sulfides; Thailand; Vero Cells | 2015 |
Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.
Topics: Antitubercular Agents; DNA Gyrase; Drug Discovery; Humans; Mycobacterium smegmatis; Mycobacterium tuberculosis | 2015 |
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis.
Topics: Antitubercular Agents; Cells, Cultured; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Triazoles | 2016 |
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles | 2016 |
A convenient and efficient approach to polyfluorosalicylic acids and their tuberculostatic activity.
Topics: Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Fluorine; Magnesium Compounds; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Salicylic Acid | 2016 |
Synthesis and antimycobacterial activity of N-(2-aminopurin-6-yl) and N-(purin-6-yl) amino acids and dipeptides.
Topics: Amino Acids; Anti-Bacterial Agents; Dipeptides; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship | 2016 |
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.
Topics: Animals; Aspergillus; Chlorocebus aethiops; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; KB Cells; Lovastatin; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium scrofulaceum; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Soil Microbiology; Thailand; Vero Cells | 2016 |
Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines.
Topics: Antitubercular Agents; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium; Pyrimidines | 2016 |
Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors.
Topics: Adenosine Triphosphatases; Antitubercular Agents; DNA Gyrase; Drug Discovery; Engineering; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Protein Conformation | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles | 2017 |
Synthesis, antimycobacterial and cytotoxic activity of α,β-unsaturated amides and 2,4-disubstituted oxazoline derivatives.
Topics: Amides; Animals; Antitubercular Agents; Liver; Microbial Sensitivity Tests; Microscopy; Mycobacterium tuberculosis; Oxazoles; Rats; Structure-Activity Relationship | 2017 |
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis | 2017 |
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water | 2017 |
Synthesis and evaluation of 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] analogues against both active and dormant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrans; Spiro Compounds; Structure-Activity Relationship; Thiophenes | 2018 |
Design, synthesis, and biological evaluation of
Topics: | 2018 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Polyketide Synthases; Structure-Activity Relationship; Vero Cells | 2019 |
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2019 |
Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules.
Topics: Antitubercular Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Polyketide Synthases; Quinolones; Structure-Activity Relationship | 2021 |
Tolerance of ofloxacin in the treatment of pulmonary tuberculosis in presence of hepatic dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1992 |
[Renal tuberculosis treated with rifampicin, isoniazid and ofloxacin].
Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Rifampin; Tuberculosis, Renal | 1992 |
[Management of INH and RFP-resistant refractory tuberculosis].
Topics: Drug Resistance; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifamycins; Tuberculosis, Pulmonary | 1991 |
In-vitro activity of ofloxacin against Mycobacterium tuberculosis and its clinical efficacy in multiply resistant pulmonary tuberculosis.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary | 1990 |
[Chemotherapeutic regimens for nontuberculous mycobacterial infection based on in-vitro susceptibility test results].
Topics: Drug Resistance, Microbial; Drug Therapy, Combination; Enviomycin; Ethambutol; Humans; Isoniazid; Mycobacterium; Mycobacterium Infections; Ofloxacin; Rifampin; Viomycin | 1990 |
[Rifabutine in the treatment of mycobacterial infections resistant to rifampicin. Preliminary results. Group for the Study and Treatment of Resistant Mycobacterial Infections (GETIM)].
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Tuberculosis, Pulmonary | 1989 |
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Pyrazinamide; Rifampin | 1989 |
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines | 1987 |
In vitro susceptibility of Mycobacterium tuberculosis to ofloxacin and ciprofloxacin in combination with rifampin and isoniazid.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Rifampin | 1987 |
[Exacerbation of pulmonary tuberculosis after diagnostic bronchoscopy and its preventive medication].
Topics: Adult; Aged; Bronchoscopy; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Retrospective Studies; Tuberculosis, Pulmonary | 1988 |
[Antituberculosis chemotherapy including ofloxacin in patients with pulmonary tuberculosis not treated previously].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Ofloxacin; Oxazines; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis | 1995 |
[Ofloxacin-cycloserine-protionamide-INH combination against treatment refractory lung tuberculosis].
Topics: Adult; AIDS-Related Opportunistic Infections; Cycloserine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Prothionamide; Recurrence; Sputum; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1995 |
[Immunotropic activity of antimicrobial agents used in tuberculosis].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cefotaxime; Cephalosporins; Erythromycin; Isoniazid; Macrophages; Mice; Ofloxacin; Time Factors; Tuberculosis | 1996 |
Bactericidal action of ofloxacin, sulbactam-ampicillin, rifampin, and isoniazid on logarithmic- and stationary-phase cultures of Mycobacterium tuberculosis.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Drug Therapy, Combination; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Penicillins; Rifampin; Sulbactam | 1996 |
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cycloserine; Ethambutol; Humans; Injections, Spinal; Isoniazid; Male; Meningitis; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Ofloxacin; Polymerase Chain Reaction; Rifampin; Streptomycin | 1996 |
[The combination of amoxicillin-clavulanic acid and ofloxacin in the treatment of multidrug-resistant Mycobacterium tuberculosis].
Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Clavulanic Acids; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Male; Ofloxacin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 1997 |
beta-Galactosidase reporter system in mycobacteria and its application in rapid antimycobacterial drug screening.
Topics: Anti-Bacterial Agents; Antitubercular Agents; beta-Galactosidase; Escherichia coli; Genes, Reporter; Isoniazid; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Plasmids; Pyrazinamide; Recombinant Proteins; Rifampin; Streptomycin | 1997 |
Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Cell Division; Drug Evaluation, Preclinical; Electroporation; Ethambutol; Green Fluorescent Proteins; Indicators and Reagents; Isoniazid; Luminescent Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Transformation, Bacterial | 1998 |
A reproducible, simple, and sensitive high-performance capillary electrophoresis method for simultaneous determination of capreomycin, ofloxacin and pasiniazide in urine.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Capreomycin; Electrophoresis, Capillary; Humans; Isoniazid; Ofloxacin; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1998 |
Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis.
Topics: Agar; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin | 2000 |
Sources of variation in studies of the early bactericidal activity of antituberculosis drugs.
Topics: Anti-Infective Agents; Antitubercular Agents; Hong Kong; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; South Africa; Sputum; Tuberculosis | 2001 |
A whole blood bactericidal assay for tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin | 2001 |
On-column amperometric detection of ofloxacin and pasiniazid in urine by capillary electrophoresis with an improved fractured joint and small detection cell.
Topics: Aminosalicylic Acid; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Combinations; Electrochemistry; Electrophoresis, Capillary; Humans; Isoniazid; Ofloxacin | 2001 |
CPCRA researchers present OI studies at Vancouver.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis | 1996 |
The treatment of multidrug-resistant tuberculosis in Turkey.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Turkey | 2001 |
[Comparison of three antituberculous drugs in serum and cold abscesses of patients with spinal tuberculosis].
Topics: Abscess; Adult; Anti-Infective Agents; Antitubercular Agents; Female; Humans; Isoniazid; Male; Ofloxacin; Rifampin; Tuberculosis, Spinal | 1998 |
Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study.
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis; Urinary Tract Infections | 2002 |
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2002 |
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2002 |
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].
Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide | 2002 |
[Tuberculoma and tuberculous meningeal-radiculitis with paradoxical progression during treatment].
Topics: Aged; Anti-Inflammatory Agents; Antitubercular Agents; Confusion; Disease Progression; Drug Therapy, Combination; Female; Fever; Humans; Immunocompetence; Isoniazid; Magnetic Resonance Imaging; Ofloxacin; Prednisone; Radiculopathy; Rifampin; Spinal Puncture; Tomography, X-Ray Computed; Treatment Outcome; Tuberculoma; Tuberculoma, Intracranial; Tuberculosis, Meningeal | 2005 |
Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates--a retrospective study from a chest-disease institute in India.
Topics: Adult; Aged; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; India; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Retrospective Studies; Rifampin; Sputum; Treatment Failure; Tuberculosis, Pulmonary | 2005 |
Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.
Topics: Capreomycin; Cycloserine; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam | 2005 |
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2005 |
Evaluation of an intracellular pharmacokinetic in vitro infection model as a tool to assess tuberculosis therapy.
Topics: Antitubercular Agents; Cell Line; Half-Life; Humans; Isoniazid; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin | 2007 |
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.
Topics: Antitubercular Agents; Bacterial Proteins; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Tuberculosis | 2007 |
[Renal mass in an HIV-positive elderly patient].
Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Nephrectomy; Ofloxacin; Pyrazinamide; Tomography, X-Ray Computed; Tuberculosis, Renal | 2009 |
Urinary Mycobacterium szulgai infection in an immunocompetent patient.
Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Immunocompetence; Isoniazid; Levofloxacin; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Rifampin; Urinary Tract Infections | 2009 |
Surveillance of drug-resistant tuberculosis in the state of Gujarat, India.
Topics: Antitubercular Agents; Bacteriological Techniques; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; India; Isoniazid; Kanamycin; Male; Microscopy, Fluorescence; Mycobacterium tuberculosis; Ofloxacin; Population Surveillance; Prevalence; Rifampin; Sputum; Tuberculosis, Multidrug-Resistant | 2009 |
Pyrosequencing for rapid detection of Mycobacterium tuberculosis resistance to rifampin, isoniazid, and fluoroquinolones.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fluoroquinolones; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Rifampin; Sequence Analysis, DNA; Time Factors | 2009 |
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective.
Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular | 2009 |
Simultaneous determination of isoniazid, rifampicin, levofloxacin in mouse tissues and plasma by high performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antibiotics, Antitubercular; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Gatifloxacin; Intestine, Small; Isoniazid; Kidney; Least-Squares Analysis; Levofloxacin; Liver; Lung; Male; Methanol; Mice; Ofloxacin; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tissue Distribution | 2010 |
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2011 |
Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa.
Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; South Africa; Streptomycin | 2011 |
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis | 2011 |
Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.
Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Streptomycin; Taiwan; Tuberculosis, Multidrug-Resistant | 2011 |
Clustering of Mycobacterium tuberculosis strains from foreign-born patients in Korea.
Topics: Antitubercular Agents; Cluster Analysis; DNA Transposable Elements; Emigrants and Immigrants; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Mycobacterium tuberculosis; Ofloxacin; Republic of Korea; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2011 |
Rapid detection of isoniazid, rifampin, and ofloxacin resistance in Mycobacterium tuberculosis clinical isolates using high-resolution melting analysis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; Molecular Diagnostic Techniques; Mycobacterium tuberculosis; Ofloxacin; Polymerase Chain Reaction; Rifampin; Sensitivity and Specificity; Transition Temperature; Tuberculosis, Multidrug-Resistant | 2011 |
[Scrofuloderma with hypersensitivity to rifampicin and pyrazinamide, treated with a combination therapy including ofloxacin].
Topics: Adult; Antibiotics, Antitubercular; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous | 2012 |
Integrated detection of multi- and extensively drug-resistant tuberculosis using the nitrate reductase assay.
Topics: Antitubercular Agents; Colorimetry; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitrate Reductase; Ofloxacin; Predictive Value of Tests; Rifampin; Sensitivity and Specificity; Time Factors; Tuberculosis, Multidrug-Resistant | 2012 |
φ(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.
Topics: Antitubercular Agents; Bacteriophages; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Promoter Regions, Genetic; Recombinant Proteins; Rifampin; Signal-To-Noise Ratio; Sputum; Tuberculosis, Pulmonary | 2012 |
Synergistic effect of two combinations of antituberculous drugs against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin | 2012 |
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant | 2012 |
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis | 2013 |
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection.
Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node | 2013 |
Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi region.
Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; Incidence; India; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Rifampin; Risk Factors; Sputum; Tuberculosis, Pulmonary | 2013 |
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2013 |
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2013 |
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis | 2013 |
Preventive therapy for child contacts of multidrug-resistant tuberculosis: a prospective cohort study.
Topics: Antitubercular Agents; Child, Preschool; Ethambutol; Female; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Male; Ofloxacin; Prospective Studies; Risk Factors; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2013 |
Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolates from China.
Topics: Antitubercular Agents; Bacterial Proteins; Capreomycin; Genotype; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis, Multidrug-Resistant | 2014 |
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Mutation; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Siberia; Tuberculosis; Young Adult | 2014 |
Performance of REBA MTB-XDR to detect extensively drug-resistant tuberculosis in an intermediate-burden country.
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genes, MDR; Humans; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Predictive Value of Tests; Republic of Korea; Rifampin; Sputum; Streptomycin | 2015 |
Second-line anti-tuberculosis drug resistance and its genetic determinants in multidrug-resistant Mycobacterium tuberculosis clinical isolates.
Topics: Adult; Aged; Amikacin; Antitubercular Agents; Base Sequence; Capreomycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Ethionamide; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2016 |
Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism.
Topics: Antitubercular Agents; Bacterial Load; Biological Transport; Cinnamates; Diffusion; Dimethylpolysiloxanes; Drug Tolerance; Epigenesis, Genetic; Humans; Hygromycin B; Isoniazid; Lab-On-A-Chip Devices; Macrophages; Microdialysis; Models, Biological; Mycobacterium smegmatis; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Rifampin | 2015 |
Prevalence of mutations conferring resistance among multi- and extensively drug-resistant Mycobacterium tuberculosis isolates in China.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; China; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genes, Bacterial; Genetic Loci; Humans; Isoniazid; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Rifampin; Sequence Analysis, DNA | 2016 |
The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sensitivity and Specificity; Sputum | 2015 |
Evaluation of the direct nitrate reductase assay for rapid detection of extensively drug-resistant tuberculosis.
Topics: Adult; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Nitrate Reductase; Ofloxacin; Prospective Studies; Rifampin; Sensitivity and Specificity; Sputum | 2016 |
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2016 |
Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Streptomycin | 2016 |
A study on pre-XDR & XDR tuberculosis & their prevalent genotypes in clinical isolates of Mycobacterium tuberculosis in north India.
Topics: Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis, Multidrug-Resistant | 2016 |
Treatment outcomes of patients with multidrug-resistant and extensively drug resistant tuberculosis in Hunan Province, China.
Topics: Adult; Antitubercular Agents; China; Cohort Studies; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Ofloxacin; Retrospective Studies; Rifampin; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2017 |
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
Comparison of line probe assay to BACTEC MGIT 960 system for susceptibility testing of first and second-line anti-tuberculosis drugs in a referral laboratory in South Africa.
Topics: Antitubercular Agents; DNA, Bacterial; Ethambutol; Female; Genotype; Humans; Isoniazid; Kanamycin; Laboratories; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Referral and Consultation; Rifampin; South Africa | 2017 |
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling.
Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant | 2018 |
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriological Techniques; Chromatography, Thin Layer; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Sensitivity and Specificity; Sputum; Tuberculosis; Young Adult | 2019 |
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing | 2020 |
Sequence-based detection of first-line and second-line drugs resistance-associated mutations in Mycobacterium tuberculosis isolates in Isfahan, Iran.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Capreomycin; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Genetic Variation; Genotype; Humans; Iran; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2020 |
Drug resistance gene mutations and treatment outcomes in MDR-TB: A prospective study in Eastern China.
Topics: Acetyltransferases; Adult; Amidohydrolases; Antitubercular Agents; Bacterial Proteins; Catalase; China; DNA Gyrase; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Multivariate Analysis; Mutation; Mutation Rate; Mycobacterium tuberculosis; Odds Ratio; Ofloxacin; Prospective Studies; Rifampin; Sequence Analysis, DNA; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2021 |
Use of Whole-Genome Sequencing to Predict
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2022 |
Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
Topics: Amikacin; Antitubercular Agents; China; Drug Resistance; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nucleotides; Ofloxacin; Rifampin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomycin; Tuberculosis, Lymph Node | 2022 |
A NiCoT family metal transporter of
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cobalt; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Ethambutol; Gentamicins; Isoleucine; Isoniazid; Kanamycin; Leucine; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Neomycin; Nickel; Norfloxacin; Ofloxacin | 2022 |