ofloxacin and isoniazid

ofloxacin has been researched along with isoniazid in 150 studies

Research

Studies (150)

TimeframeStudies, this research(%)All Research%
pre-19906 (4.00)18.7374
1990's22 (14.67)18.2507
2000's33 (22.00)29.6817
2010's81 (54.00)24.3611
2020's8 (5.33)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
China, A; Dinakaran, M; Nagaraja, V; Senthilkumar, P; Sriram, D; Yogeeswari, P1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M1
Govender, K; Govender, P; Govender, T; Kruger, HG; Maguire, GE; Muthusamy, K; Onajole, OK; Pillay, M; van Helden, PD; Wiid, I1
Banerjee, D; Bhat, P; Dinakaran, M; Gadhwal, S; Sriram, D; Yogeeswari, P1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ1
Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Senadeera, SP; Sureram, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chestnova, RV; Fattakhov, SG; Mingaleev, DN; Reznik, VS; Saifina, LF; Shulaeva, MM; Valijev, RSh; Voloshina, AD1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T1
Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH1
Achar, V; Arora, U; Awasthy, D; Bharath, S; Bheemarao, U; Chinnapattu, M; Coulson, M; de Sousa, SM; Ganguly, S; Gaonkar, S; Ghosh, A; Hameed P, S; Hoffner, S; Humnabadkar, V; Kaur, P; Kumar K N, M; Kumar, CN; Madhavapeddi, P; Manjrekar, P; Menasinakai, S; Mukherjee, K; Nandishaiah, R; Narayan, C; Panduga, V; Patil, V; Puttur, J; Raichurkar, A; Ramya, VK; Reddy, J; Rudrapatana, S; Sambandamurthy, VK; Shanbhag, G; Sharma, S; Sharma, U; Shinde, V; Solapure, S; Waterson, D; Werngren, J1
Ambady, A; Guptha, S; Hegde, N; Hosagrahara, VP; Humnabadkar, V; Kaur, P; Mahadevaswamy, J; Nagalapur, K; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, S; Ramachandran, V; Rudrapatna, SS; Sambandamurthy, VK; Sharma, S; Shirude, PS1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P1
Babu, KS; Jeankumar, VU; Reddy, KI; Renuka, J; Shravan, M; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P1
Devi, PB; Jeankumar, VU; Pedgaonkar, GS; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P2
Babu, KS; Chuppala, A; Jeankumar, VU; Reddy, KI; Renuka, J; Sree, KS; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P1
Aree, T; Ganihigama, DU; Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Sangher, S; Sureram, S1
Bowornwiriyapan, K; Daengrot, C; Phongpaichit, S; Rukachaisirikul, V; Sakayaroj, J; Tansakul, C; Thongpanchang, T1
Renuka, J; Samala, G; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P1
Dixit, PP; Thore, SN1
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Burgart, YV; Krasnykh, OP; Kravchenko, MA; Saloutin, VI; Shchegol'kov, EV; Shchur, IV; Solodnikov, SY1
Bekker, OB; Charushin, VN; Danilenko, VN; Gruzdev, DA; Krasnov, VP; Kravchenko, MA; Levit, GL; Matveeva, TV; Musiyak, VV; Nizova, IA; Skornyakov, SN; Vigorov, AY1
Bowornwiriyapan, K; Duangjai, A; Muanprasat, C; Phainuphong, P; Phongpaichit, S; Rukachaisirikul, V; Saithong, S; Sakayaroj, J; Srimaroeng, C1
Baskakova, SA; Charushin, VN; Chupakhin, ON; Kravchenko, MA; Rusinov, GL; Skornyakov, SN; Verbitskiy, EV1
Janupally, R; Jeankumar, VU; Reshma, RS; Saxena, S; Sriram, D; Vats, R; Yogeeswari, P1
Chaudhari, K; Jain, P; Patel, HM; Surana, S1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K1
Avalos-Alanís, FG; Carranza-Rosales, P; Guzmán-Delgado, NE; Hernández-Fernández, E; Hernández-Fernández, J; López-Cortina, S; Morales-Vargas, A; Ordóñez, M; Santiago-Mauricio, MG; Velázquez-Moreno, VM1
Mahajan, SS; Saharan, VD1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H1
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ1
Alluri, KK; Gottapu, S; Reshma, RS; Sriram, D; Suraparaju, R1
Gao, YM; Liang, J; Liu, ZY; Qian, L; Tang, YX; Yan, M; Zhang, NN; Zhang, TY1
Bishai, WR; Duan, G; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Xiao, S; Yang, F; Yu, LF; Zhang, W1
Bera, S; Mondal, D1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K1
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR1
Bishai, WR; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Wang, SS; Xiao, S; Yang, F; Yu, LF; Zhang, W1
Kwan, SY; Lee, J; Wong, PC; Yew, WW1
Hara, K; Kaku, M; Koga, H; Kohno, S; Maesaki, S1
Alberte, A; Estébanez, MJ; Martínez-Sagarra, JM; Pascual, PP1
Chau, PY; Khin, MA; Kwan, SY; Ma, WK; Yew, WW1
Tsukamura, M; Yamori, S1
Heap, BJ1
Berlin, OG; Bruckner, DA; Young, LS1
Casal, M; González, J; Gutierrez, J; Ruiz, P1
Arai, R; Furuse, K; Kawahara, M; Kita, N; Sakatani, M1
Saito, H; Tsukamura, M; Yasuda, Y; Yoshii, S1
Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C1
Mühlberger, F; Nasbimana, J; Nturanye, F; Portaels, F1
Aleksandrova, AE; Vinogradova, TI1
Herbert, D; Kubendiran, G; Mitchison, DA; Paramasivan, CN; Prabhakar, R; Venkatesan, P1
Hadiarto, M; Hudoyo, A; Tjandra, YA1
Furukawa, T; Komachi, H; Nagai, R; Saito, Y; Takewaki, S; Uchihara, T1
Hirose, T; Ikeda, T; Iwanaga, T; Kishikawa, R; Nishima, S; Tsurutani, H; Yokota, K1
Kumar, D; Srivastava, BS; Srivastava, R; Subramaniam, P1
Padeĭskaia, EN1
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE1
Collins, LA; Franzblau, SG; Torrero, MN1
Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE1
Liu, HX; Yu, CL; Yuan, ZB; Zhang, SS1
Donald, PR; Githui, W; Kam, KM; Lam, CW; Mitchison, DA; Odhiambo, J; Paramasivan, CN; Sirgel, FA; Sole, KM; Tam, CM; Umapathy, KC1
Bajaksouzian, S; Jacobs, MR; Joloba, ML1
Mitchison, D; Sirgel, F; Venter, A1
Cheon, SH; Dietze, R; Ellner, JJ; Hise, AG; Landen, K; Palaci, M; Phillips, M; Ribeiro, FC; Song, HY; Vinhas, S; Wallis, RS1
Liu, HX; Wu, YJ; Yu, CL; Zhang, SS1
Bowersox, J1
Ataç, G; Kapakli, N; Karasulu, L; Kir, A; Ozmen, I; Sevim, T; Tahaoğlu, K; Törün, T1
Duan, L; Lin, Y; Wu, Q1
Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE1
Bogadel'nikova, IV; Kunichan, AD; Semenova, OV; Sokolova, GB1
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA1
Kunichan, AD; Litovchenko, KV; Sokolova, GB; Tsybanev, AA1
Li, SM; Xing, BC; Zheng, XM1
Gurumurthy, P; Kumar, AK1
Boibieux, A; Chidiac, C; Issartel, B; Petiot, P; Peyramond, D; Rabar, D1
Bose, M; Dam, T; Isa, M1
Hoeppner, VH; Jones, W; Marciniuk, DD; Ward, HA1
Bhusal, Y; Shiohira, CM; Yamane, N1
Farnia, P; Khoshnood, K; Mansoori, SD; Masjedi, H; Masjedi, MR; Mirsaeidi, SM; Mohammadi, F; Pooramiri, MV; Rowhani-Rahbar, A; Tabarsi, P; Velayati, AA; Zahirifard, S1
Cappelletty, DM1
Otomo, K; Shi, R; Sugawara, I; Zhang, G; Zhang, J1
Allen, J; Coleman, DJ; Davies, GR; Fourie, B; Kanyok, T; Levin, J; Lienhardt, C; Mitchison, DA; Mthiyane, T; Reddy, C; Rustomjee, R; Sirgel, FA; Sturm, AW1
Martínez, E; Nam-Cha, S; Puerta, A; Salinas, A1
Chen, YH; Eng, HL; Huang, CK; Lai, CH; Lin, HF; Lin, HH; Lin, JN1
Chadha, S; Chandrasekar, V; Chauhan, LS; Dave, PV; Dewan, P; Nalini, S; Narayanan, PR; Paramasivan, CN; Parmar, M; Ramachandran, R; Sahu, S; Sanghvi, AS; Wares, F1
Ang, C; Bravo, LT; Destura, RV; Gordon, SM; Hall, GS; Mendoza, M; Procop, GW; Shrestha, NK; Tuohy, MJ1
Agarwal, A; Arora, A; Kumar, S1
Cai, HL; Chen, YC; Fang, PF; Gao, W; Li, HD; Liu, YP; Tan, QY; Xu, P; Zhang, F; Zhang, WY; Zhu, RH1
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A1
Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA1
Connolly, C; Friedland, G; Gandhi, N; Moodley, P; Shah, NS; Sturm, AW; Tayob, N; Zetola, N1
Cremades, R; Galiana, A; García-Pachón, E; López, P; Rodríguez, JC; Royo, G; Ruiz-García, M1
Hsueh, PR; Huang, YT; Lai, CC; Liao, CH; Tan, CK1
Cho, EH; Jeon, CY; Kang, H; Kim, H; Kim, M; Murray, MB; Park, YK1
Chen, X; Gilbert, GL; Kong, F; Li, C; Wang, Q; Zhang, J1
Badri, T; Belghith, I; Benmously, R; Mokhtar, I; Zaiem, A1
de Rijk, P; Fissette, K; Martin, A; Palomino, JC; Ramos, E1
Eisenberg, N; Govender, K; Hartman, TE; Hatfull, GF; Jacobs, WR; Jain, P; Kriakov, J; Larsen, MH; Makume, M; Moodley, P; O'Donnell, MR; Sturm, AW; Thaler, DS1
González-Martín, J; Martínez, JA; Rey-Jurado, E; Tudó, G1
Hassan, G; Kant, S; Parengal, J; Saheer, S1
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y1
Bergmann, JF; Cambau, E; Evans, J; Hoang-Nguyen, DT; Lloret-Linares, C; Lopes, A; Mouly, S; Raskine, L; Sellier, P1
Banavaliker, JN; Behera, D; Bhatnagar, AK; Hanif, M; Kaushik, A; Makkar, N; Pande, JN; Porwal, C; Singh, UB; Singla, R1
Choe, KH; Chung, GT; Hwang, SC; Jnawali, HN; Kim, H; Lee, YS; Park, YK; Ryoo, S1
Chikamatsu, K; Fujita, A; Matsumoto, T; Mitarai, S; Mizuno, K; Ogata, H; Saito, T; Suetake, T; Suzuki, K; Toyota, E1
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A1
Cox, H; Fielding, K; Finlayson, H; Godfrey-Faussett, P; Hesseling, AC; Hughes, J; Schaaf, HS; Seddon, JA1
Chen, Y; Li, GL; Liu, HC; Liu, ZG; Sun, Q; Wan, KL; Wu, XC; Xia, Q; Zhao, LL; Zhao, XQ1
Alkhovik, OI; Cherednichenko, AG; Dymova, MA; Filipenko, ML; Khrapov, EA; Petrenko, TI1
Choi, SB; Jo, KW; Jung, H; Kang, MR; Lee, YS; Shim, TS1
Augustynowicz-Kopeć, E; Bakuła, Z; Bielecki, J; Jagielski, T; Kamiński, M; Napiórkowska, A; Zwolska, Z1
Balagaddé, FK; Luthuli, BB; Purdy, GE1
Chen, Y; Liu, HC; Liu, ZG; Sun, Q; Wan, KL; Zhao, B; Zhao, LL; Zhao, XQ1
Ardizzoni, E; Aspindzelashvili, R; Bastard, M; de Jong, BC; Goginashvili, L; Kotrikadze, T; Mulders, W; Pangtey, H; Rigouts, L; Varaine, F1
Deng, YT; Huang, ZK; Li, JM; Luo, Q; Qing, C; Xiong, GL1
Chen, ST; Huang, HR; Jiang, GL; Ma, YF; Wang, GR; Yu, X1
Abbas, M; Ehtisham-Ul-Haque, S; Javed, I; Javed, MT; Mahmood, Z; Riaz, M; Shahid, M1
Dixit, P; Jain, A; Jaiswal, I; Singh, M; Singh, P; Singhal, P1
Campanerut-Sá, PAZ; Cardoso, RF; Ghiraldi-Lopes, LD; Meneguello, JE; Pavan, FR; Scodro, RBL; Siqueira, VLD; Svidzinski, TIE; Teixeira, JJV1
Alene, KA; Bai, L; Clements, ACA; Gray, DJ; McBryde, ES; Viney, K; Xu, Z; Yang, K; Yi, H1
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR1
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T1
Antiabong, JF; Lekalakala, RM; Malinga, LA; Maningi, NE; Mbelle, NM1
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM1
Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G1
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F1
Jafari, R; Moghim, S; Nasr Esfahani, B; Safari, M; Salehi, M1
Ji, Y; Li, Z; Liu, Q; Martinez, L; Qiu, B; Song, H; Wang, J; Yang, D1
Guo, Y; Liu, H; Sha, W; Shen, H; Shen, X; Tan, G; Wu, X; Wu, Z; Yang, J; Yu, F1
Guo, Y; Huang, C; Sha, W; Tan, G; Wu, X; Yang, J; Yu, F1
Adhikary, A; Biswal, S; Chatterjee, D; Ghosh, AS1

Reviews

8 review(s) available for ofloxacin and isoniazid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Mycobacterium Tuberculosis (MTB) GyrB inhibitors: An attractive approach for developing novel drugs against TB.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Antitubercular Agents; Clinical Trials as Topic; DNA Gyrase; Drug Discovery; Humans; Mycobacterium tuberculosis; Topoisomerase II Inhibitors

2016
Fluoroquinolone derivatives and their anti-tubercular activities.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis

2018
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis

2021
[Value of ciprofloxacin in the therapy of tuberculosis and other mycobacterioses].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1997, Volume: 42, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections; Ofloxacin; Rifampin

1997
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
    The Lancet. Infectious diseases, 2010, Volume: 10, Issue:9

    Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis

2010
Systematic review on the proteomic profile of Mycobacterium tuberculosis exposed to drugs.
    Proteomics. Clinical applications, 2017, Volume: 11, Issue:11-12

    Topics: Anti-Bacterial Agents; Electrophoresis, Gel, Two-Dimensional; Fluoroquinolones; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Proteome; Proteomics; Streptomycin

2017

Trials

11 trial(s) available for ofloxacin and isoniazid

ArticleYear
A controlled study of rifabutin and an uncontrolled study of ofloxacin in the retreatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin and rifampicin. Hong Kong Chest Service/British Medical Research Council.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1992, Volume: 73, Issue:1

    Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Sputum; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary

1992
Prospective comparative study of ofloxacin or ethambutol for the treatment of pulmonary tuberculosis.
    Chest, 1992, Volume: 102, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Combinations; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Prospective Studies; Rifampin; Time Factors; Tuberculosis, Pulmonary

1992
Treatment of multidrug-resistant tuberculosis in Indonesia.
    Chemotherapy, 1996, Volume: 42 Suppl 3

    Topics: Adult; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nausea; Ofloxacin; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant

1996
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
    AIDS (London, England), 1997, Volume: 11, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis

1997
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary

1998
A multicentre study of the early bactericidal activity of anti-tuberculosis drugs.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:6

    Topics: Adult; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Hong Kong; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; South Africa; Sputum; Tuberculosis, Pulmonary

2000
[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2004, Volume: 24, Issue:5

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Clinical Protocols; Drug Therapy, Combination; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Ofloxacin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2004
Disposition of uric acid upon administration of ofloxacin alone and in combination with other anti-tuberculosis drugs.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:3

    Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Humans; Isoniazid; Male; Ofloxacin; Pyrazinamide; Rifampin; Uric Acid

2004
Treatment of multiple drug-resistant tuberculosis (MDR-TB) in Iran.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2005, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Aged; Amikacin; Antitubercular Agents; Cycloserine; Drug Therapy, Combination; Female; Humans; Iran; Isoniazid; Male; Middle Aged; Ofloxacin; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2005
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2008, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Nonlinear Dynamics; Ofloxacin; Pyrazinamide; Quinolines; Rifampin; Sputum

2008
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult

2011

Other Studies

131 other study(ies) available for ofloxacin and isoniazid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Animals; Antitubercular Agents; Combinatorial Chemistry Techniques; DNA Gyrase; Enzyme Inhibitors; Fluoroquinolones; Gatifloxacin; Lung; Mice; Molecular Structure; Mycobacterium tuberculosis; Ofloxacin; Spleen; Structure-Activity Relationship; Topoisomerase II Inhibitors

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis

2009
Pentacyclo-undecane derived cyclic tetra-amines: synthesis and evaluation as potent anti-tuberculosis agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Alkanes; Animals; Antitubercular Agents; Cattle; Cell Line; Cell Survival; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Prenylation

2009
Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno[3,2-c]pyridin-3-yl derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Microbial Sensitivity Tests; Pyridines; Vero Cells

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin

2010
Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Alkaloids; Antitubercular Agents; Benzylisoquinolines; Drug Resistance, Multiple, Bacterial; Humans; Magnetic Resonance Spectroscopy; Menispermaceae; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Plant Extracts; Plant Roots; Tuberculosis, Multidrug-Resistant

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Synthesis and antimycobacterial activity of novel 1,3-dimethylisocyanurate derivatives.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Amides; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rats; Structure-Activity Relationship; Sulfonic Acids; Triazines

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells

2012
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
    Journal of natural products, 2013, Nov-22, Volume: 76, Issue:11

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells

2013
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Acute Disease; Administration, Oral; Animals; Antitubercular Agents; Bacterial Proteins; Biological Availability; Chronic Disease; DNA Gyrase; Drug Resistance, Bacterial; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Macrophages; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Piperidines; Protein Subunits; Rats; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tuberculosis, Pulmonary

2014
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pyrazoles; Pyridones; Structure-Activity Relationship

2014
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17

    Topics: Animals; Antitubercular Agents; Benzofurans; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Acetamides; Animals; Bacterial Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Quinazolines; Structure-Activity Relationship; Tuberculosis

2014
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
    Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Cell Line; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Structure-Activity Relationship; Tuberculosis

2014
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.
    Bioorganic & medicinal chemistry, 2014, Dec-01, Volume: 22, Issue:23

    Topics: Animals; Antitubercular Agents; Benzofurans; Benzothiazoles; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Structure-Activity Relationship; Topoisomerase II Inhibitors

2014
Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Antitubercular Agents; Biological Products; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Quinolines; Structure-Activity Relationship

2015
Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138.
    Journal of natural products, 2015, Apr-24, Volume: 78, Issue:4

    Topics: Animals; Antimalarials; Antineoplastic Agents; Biphenyl Compounds; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Penicillium; Plasmodium falciparum; Sesquiterpenes; Soil Microbiology; Sulfides; Thailand; Vero Cells

2015
Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.
    Bioorganic & medicinal chemistry, 2015, Apr-01, Volume: 23, Issue:7

    Topics: Antitubercular Agents; DNA Gyrase; Drug Discovery; Humans; Mycobacterium smegmatis; Mycobacterium tuberculosis

2015
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Antitubercular Agents; Cells, Cultured; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Triazoles

2016
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles

2016
A convenient and efficient approach to polyfluorosalicylic acids and their tuberculostatic activity.
    Bioorganic & medicinal chemistry letters, 2016, 05-15, Volume: 26, Issue:10

    Topics: Antitubercular Agents; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Fluorine; Magnesium Compounds; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Salicylic Acid

2016
Synthesis and antimycobacterial activity of N-(2-aminopurin-6-yl) and N-(purin-6-yl) amino acids and dipeptides.
    Bioorganic & medicinal chemistry letters, 2016, 06-01, Volume: 26, Issue:11

    Topics: Amino Acids; Anti-Bacterial Agents; Dipeptides; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Structure-Activity Relationship

2016
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.
    Journal of natural products, 2016, 06-24, Volume: 79, Issue:6

    Topics: Animals; Aspergillus; Chlorocebus aethiops; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; KB Cells; Lovastatin; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium scrofulaceum; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Soil Microbiology; Thailand; Vero Cells

2016
Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines.
    Bioorganic & medicinal chemistry, 2016, 08-15, Volume: 24, Issue:16

    Topics: Antitubercular Agents; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium; Pyrimidines

2016
Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Adenosine Triphosphatases; Antitubercular Agents; DNA Gyrase; Drug Discovery; Engineering; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Protein Conformation

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles

2017
Synthesis, antimycobacterial and cytotoxic activity of α,β-unsaturated amides and 2,4-disubstituted oxazoline derivatives.
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Amides; Animals; Antitubercular Agents; Liver; Microbial Sensitivity Tests; Microscopy; Mycobacterium tuberculosis; Oxazoles; Rats; Structure-Activity Relationship

2017
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis

2017
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water

2017
Synthesis and evaluation of 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] analogues against both active and dormant Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8

    Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrans; Spiro Compounds; Structure-Activity Relationship; Thiophenes

2018
Design, synthesis, and biological evaluation of
    MedChemComm, 2018, Aug-01, Volume: 9, Issue:8

    Topics:

2018
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
    Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Polyketide Synthases; Structure-Activity Relationship; Vero Cells

2019
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles

2019
Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Antitubercular Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Polyketide Synthases; Quinolones; Structure-Activity Relationship

2021
Tolerance of ofloxacin in the treatment of pulmonary tuberculosis in presence of hepatic dysfunction.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Liver Function Tests; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Pulmonary

1992
[Renal tuberculosis treated with rifampicin, isoniazid and ofloxacin].
    Enfermedades infecciosas y microbiologia clinica, 1992, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Rifampin; Tuberculosis, Renal

1992
[Management of INH and RFP-resistant refractory tuberculosis].
    Kekkaku : [Tuberculosis], 1991, Volume: 66, Issue:10

    Topics: Drug Resistance; Female; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifamycins; Tuberculosis, Pulmonary

1991
In-vitro activity of ofloxacin against Mycobacterium tuberculosis and its clinical efficacy in multiply resistant pulmonary tuberculosis.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Microbial; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sputum; Streptomycin; Tuberculosis, Pulmonary

1990
[Chemotherapeutic regimens for nontuberculous mycobacterial infection based on in-vitro susceptibility test results].
    Kekkaku : [Tuberculosis], 1990, Volume: 65, Issue:5

    Topics: Drug Resistance, Microbial; Drug Therapy, Combination; Enviomycin; Ethambutol; Humans; Isoniazid; Mycobacterium; Mycobacterium Infections; Ofloxacin; Rifampin; Viomycin

1990
[Rifabutine in the treatment of mycobacterial infections resistant to rifampicin. Preliminary results. Group for the Study and Treatment of Resistant Mycobacterial Infections (GETIM)].
    Revue des maladies respiratoires, 1989, Volume: 6, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Tuberculosis, Pulmonary

1989
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
    Tubercle, 1989, Volume: 70, Issue:3

    Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Pyrazinamide; Rifampin

1989
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 19, Issue:5

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines

1987
In vitro susceptibility of Mycobacterium tuberculosis to ofloxacin and ciprofloxacin in combination with rifampin and isoniazid.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:6

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Synergism; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Oxazines; Rifampin

1987
[Exacerbation of pulmonary tuberculosis after diagnostic bronchoscopy and its preventive medication].
    Kekkaku : [Tuberculosis], 1988, Volume: 63, Issue:12

    Topics: Adult; Aged; Bronchoscopy; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Retrospective Studies; Tuberculosis, Pulmonary

1988
[Antituberculosis chemotherapy including ofloxacin in patients with pulmonary tuberculosis not treated previously].
    Kekkaku : [Tuberculosis], 1986, Volume: 61, Issue:1

    Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Ofloxacin; Oxazines; Rifampin; Streptomycin; Tuberculosis, Pulmonary

1986
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis

1995
[Ofloxacin-cycloserine-protionamide-INH combination against treatment refractory lung tuberculosis].
    Pneumologie (Stuttgart, Germany), 1995, Volume: 49, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cycloserine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Prothionamide; Recurrence; Sputum; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

1995
[Immunotropic activity of antimicrobial agents used in tuberculosis].
    Problemy tuberkuleza, 1996, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cefotaxime; Cephalosporins; Erythromycin; Isoniazid; Macrophages; Mice; Ofloxacin; Time Factors; Tuberculosis

1996
Bactericidal action of ofloxacin, sulbactam-ampicillin, rifampin, and isoniazid on logarithmic- and stationary-phase cultures of Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:10

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Drug Therapy, Combination; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Penicillins; Rifampin; Sulbactam

1996
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
    Journal of the neurological sciences, 1996, Volume: 143, Issue:1-2

    Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cycloserine; Ethambutol; Humans; Injections, Spinal; Isoniazid; Male; Meningitis; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Ofloxacin; Polymerase Chain Reaction; Rifampin; Streptomycin

1996
[The combination of amoxicillin-clavulanic acid and ofloxacin in the treatment of multidrug-resistant Mycobacterium tuberculosis].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:1

    Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Clavulanic Acids; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoniazid; Male; Ofloxacin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

1997
beta-Galactosidase reporter system in mycobacteria and its application in rapid antimycobacterial drug screening.
    Biochemical and biophysical research communications, 1997, Jun-27, Volume: 235, Issue:3

    Topics: Anti-Bacterial Agents; Antitubercular Agents; beta-Galactosidase; Escherichia coli; Genes, Reporter; Isoniazid; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Plasmids; Pyrazinamide; Recombinant Proteins; Rifampin; Streptomycin

1997
Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:2

    Topics: Anti-Infective Agents; Antitubercular Agents; Cell Division; Drug Evaluation, Preclinical; Electroporation; Ethambutol; Green Fluorescent Proteins; Indicators and Reagents; Isoniazid; Luminescent Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Transformation, Bacterial

1998
A reproducible, simple, and sensitive high-performance capillary electrophoresis method for simultaneous determination of capreomycin, ofloxacin and pasiniazide in urine.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:4-5

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Capreomycin; Electrophoresis, Capillary; Humans; Isoniazid; Ofloxacin; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1998
Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis.
    Journal of clinical microbiology, 2000, Volume: 38, Issue:10

    Topics: Agar; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin

2000
Sources of variation in studies of the early bactericidal activity of antituberculosis drugs.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:2

    Topics: Anti-Infective Agents; Antitubercular Agents; Hong Kong; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; South Africa; Sputum; Tuberculosis

2001
A whole blood bactericidal assay for tuberculosis.
    The Journal of infectious diseases, 2001, Apr-15, Volume: 183, Issue:8

    Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin

2001
On-column amperometric detection of ofloxacin and pasiniazid in urine by capillary electrophoresis with an improved fractured joint and small detection cell.
    The Analyst, 2001, Volume: 126, Issue:4

    Topics: Aminosalicylic Acid; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Combinations; Electrochemistry; Electrophoresis, Capillary; Humans; Isoniazid; Ofloxacin

2001
CPCRA researchers present OI studies at Vancouver.
    NIAID AIDS agenda, 1996

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis

1996
The treatment of multidrug-resistant tuberculosis in Turkey.
    The New England journal of medicine, 2001, Jul-19, Volume: 345, Issue:3

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Isoniazid; Logistic Models; Male; Middle Aged; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Turkey

2001
[Comparison of three antituberculous drugs in serum and cold abscesses of patients with spinal tuberculosis].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1998, Volume: 21, Issue:10

    Topics: Abscess; Adult; Anti-Infective Agents; Antitubercular Agents; Female; Humans; Isoniazid; Male; Ofloxacin; Rifampin; Tuberculosis, Spinal

1998
Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study.
    International microbiology : the official journal of the Spanish Society for Microbiology, 2002, Volume: 5, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Treatment Outcome; Tuberculosis; Urinary Tract Infections

2002
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:6

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin

2002
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:3

    Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis

2002
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:12

    Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide

2002
[Tuberculoma and tuberculous meningeal-radiculitis with paradoxical progression during treatment].
    Presse medicale (Paris, France : 1983), 2005, Jan-15, Volume: 34, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Antitubercular Agents; Confusion; Disease Progression; Drug Therapy, Combination; Female; Fever; Humans; Immunocompetence; Isoniazid; Magnetic Resonance Imaging; Ofloxacin; Prednisone; Radiculopathy; Rifampin; Spinal Puncture; Tomography, X-Ray Computed; Treatment Outcome; Tuberculoma; Tuberculoma, Intracranial; Tuberculosis, Meningeal

2005
Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates--a retrospective study from a chest-disease institute in India.
    Journal of medical microbiology, 2005, Volume: 54, Issue:Pt 3

    Topics: Adult; Aged; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Humans; India; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Retrospective Studies; Rifampin; Sputum; Treatment Failure; Tuberculosis, Pulmonary

2005
Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2005, Volume: 9, Issue:2

    Topics: Capreomycin; Cycloserine; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam

2005
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
    International journal of antimicrobial agents, 2005, Volume: 26, Issue:4

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis

2005
Evaluation of an intracellular pharmacokinetic in vitro infection model as a tool to assess tuberculosis therapy.
    International journal of antimicrobial agents, 2007, Volume: 29, Issue:2

    Topics: Antitubercular Agents; Cell Line; Half-Life; Humans; Isoniazid; Levofloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin

2007
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Antitubercular Agents; Bacterial Proteins; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Tuberculosis

2007
[Renal mass in an HIV-positive elderly patient].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2

    Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Nephrectomy; Ofloxacin; Pyrazinamide; Tomography, X-Ray Computed; Tuberculosis, Renal

2009
Urinary Mycobacterium szulgai infection in an immunocompetent patient.
    Southern medical journal, 2009, Volume: 102, Issue:9

    Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Immunocompetence; Isoniazid; Levofloxacin; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Rifampin; Urinary Tract Infections

2009
Surveillance of drug-resistant tuberculosis in the state of Gujarat, India.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2009, Volume: 13, Issue:9

    Topics: Antitubercular Agents; Bacteriological Techniques; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; India; Isoniazid; Kanamycin; Male; Microscopy, Fluorescence; Mycobacterium tuberculosis; Ofloxacin; Population Surveillance; Prevalence; Rifampin; Sputum; Tuberculosis, Multidrug-Resistant

2009
Pyrosequencing for rapid detection of Mycobacterium tuberculosis resistance to rifampin, isoniazid, and fluoroquinolones.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:12

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fluoroquinolones; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Rifampin; Sequence Analysis, DNA; Time Factors

2009
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective.
    The Indian journal of tuberculosis, 2009, Volume: 56, Issue:4

    Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular

2009
Simultaneous determination of isoniazid, rifampicin, levofloxacin in mouse tissues and plasma by high performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Aug-15, Volume: 878, Issue:24

    Topics: Animals; Antibiotics, Antitubercular; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Gatifloxacin; Intestine, Small; Isoniazid; Kidney; Least-Squares Analysis; Levofloxacin; Liver; Lung; Male; Methanol; Mice; Ofloxacin; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tissue Distribution

2010
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5

    Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin

2011
Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; South Africa; Streptomycin

2011
Comparison of the bactericidal activity of various fluoroquinolones against Mycobacterium tuberculosis in an in vitro experimental model.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10

    Topics: Antitubercular Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Spain; Tuberculosis

2011
Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Streptomycin; Taiwan; Tuberculosis, Multidrug-Resistant

2011
Clustering of Mycobacterium tuberculosis strains from foreign-born patients in Korea.
    Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 12

    Topics: Antitubercular Agents; Cluster Analysis; DNA Transposable Elements; Emigrants and Immigrants; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Mycobacterium tuberculosis; Ofloxacin; Republic of Korea; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant

2011
Rapid detection of isoniazid, rifampin, and ofloxacin resistance in Mycobacterium tuberculosis clinical isolates using high-resolution melting analysis.
    Journal of clinical microbiology, 2011, Volume: 49, Issue:10

    Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; Molecular Diagnostic Techniques; Mycobacterium tuberculosis; Ofloxacin; Polymerase Chain Reaction; Rifampin; Sensitivity and Specificity; Transition Temperature; Tuberculosis, Multidrug-Resistant

2011
[Scrofuloderma with hypersensitivity to rifampicin and pyrazinamide, treated with a combination therapy including ofloxacin].
    Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:4

    Topics: Adult; Antibiotics, Antitubercular; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Cutaneous

2012
Integrated detection of multi- and extensively drug-resistant tuberculosis using the nitrate reductase assay.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Colorimetry; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitrate Reductase; Ofloxacin; Predictive Value of Tests; Rifampin; Sensitivity and Specificity; Time Factors; Tuberculosis, Multidrug-Resistant

2012
φ(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.
    Journal of clinical microbiology, 2012, Volume: 50, Issue:4

    Topics: Antitubercular Agents; Bacteriophages; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Promoter Regions, Genetic; Recombinant Proteins; Rifampin; Signal-To-Noise Ratio; Sputum; Tuberculosis, Pulmonary

2012
Synergistic effect of two combinations of antituberculous drugs against Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2012, Volume: 92, Issue:3

    Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin

2012
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
    BMJ case reports, 2012, May-08, Volume: 2012

    Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant

2012
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis

2013
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:1

    Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node

2013
Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi region.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; Incidence; India; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Rifampin; Risk Factors; Sputum; Tuberculosis, Pulmonary

2013
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
    Diagnostic microbiology and infectious disease, 2013, Volume: 76, Issue:2

    Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant

2013
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis].
    Kekkaku : [Tuberculosis], 2013, Volume: 88, Issue:3

    Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin

2013
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:9

    Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis

2013
Preventive therapy for child contacts of multidrug-resistant tuberculosis: a prospective cohort study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 57, Issue:12

    Topics: Antitubercular Agents; Child, Preschool; Ethambutol; Female; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Male; Ofloxacin; Prospective Studies; Risk Factors; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2013
Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolates from China.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:4

    Topics: Antitubercular Agents; Bacterial Proteins; Capreomycin; Genotype; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis, Multidrug-Resistant

2014
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
    BMC infectious diseases, 2014, Sep-03, Volume: 14

    Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Mutation; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Siberia; Tuberculosis; Young Adult

2014
Performance of REBA MTB-XDR to detect extensively drug-resistant tuberculosis in an intermediate-burden country.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2015, Volume: 21, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Genes, MDR; Humans; Isoniazid; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Predictive Value of Tests; Republic of Korea; Rifampin; Sputum; Streptomycin

2015
Second-line anti-tuberculosis drug resistance and its genetic determinants in multidrug-resistant Mycobacterium tuberculosis clinical isolates.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2016, Volume: 49, Issue:3

    Topics: Adult; Aged; Amikacin; Antitubercular Agents; Base Sequence; Capreomycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Ethionamide; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant

2016
Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Antitubercular Agents; Bacterial Load; Biological Transport; Cinnamates; Diffusion; Dimethylpolysiloxanes; Drug Tolerance; Epigenesis, Genetic; Humans; Hygromycin B; Isoniazid; Lab-On-A-Chip Devices; Macrophages; Microdialysis; Models, Biological; Mycobacterium smegmatis; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Rifampin

2015
Prevalence of mutations conferring resistance among multi- and extensively drug-resistant Mycobacterium tuberculosis isolates in China.
    The Journal of antibiotics, 2016, Volume: 69, Issue:3

    Topics: Antitubercular Agents; Bacterial Proteins; Catalase; China; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genes, Bacterial; Genetic Loci; Humans; Isoniazid; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Rifampin; Sequence Analysis, DNA

2016
The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:12

    Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sensitivity and Specificity; Sputum

2015
Evaluation of the direct nitrate reductase assay for rapid detection of extensively drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:4

    Topics: Adult; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Nitrate Reductase; Ofloxacin; Prospective Studies; Rifampin; Sensitivity and Specificity; Sputum

2016
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:3

    Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis

2016
Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.
    International journal of immunopathology and pharmacology, 2016, Volume: 29, Issue:3

    Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Streptomycin

2016
A study on pre-XDR & XDR tuberculosis & their prevalent genotypes in clinical isolates of Mycobacterium tuberculosis in north India.
    The Indian journal of medical research, 2016, Volume: 143, Issue:3

    Topics: Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis, Multidrug-Resistant

2016
Treatment outcomes of patients with multidrug-resistant and extensively drug resistant tuberculosis in Hunan Province, China.
    BMC infectious diseases, 2017, 08-16, Volume: 17, Issue:1

    Topics: Adult; Antitubercular Agents; China; Cohort Studies; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Ofloxacin; Retrospective Studies; Rifampin; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2017
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
    Annals of clinical microbiology and antimicrobials, 2017, Aug-18, Volume: 16, Issue:1

    Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant

2017
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
    Bioinformatics (Oxford, England), 2018, 05-15, Volume: 34, Issue:10

    Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant

2018
Comparison of line probe assay to BACTEC MGIT 960 system for susceptibility testing of first and second-line anti-tuberculosis drugs in a referral laboratory in South Africa.
    BMC infectious diseases, 2017, 12-28, Volume: 17, Issue:1

    Topics: Antitubercular Agents; DNA, Bacterial; Ethambutol; Female; Genotype; Humans; Isoniazid; Kanamycin; Laboratories; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Referral and Consultation; Rifampin; South Africa

2017
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12

    Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant

2018
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriological Techniques; Chromatography, Thin Layer; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Sensitivity and Specificity; Sputum; Tuberculosis; Young Adult

2019
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 96

    Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing

2020
Sequence-based detection of first-line and second-line drugs resistance-associated mutations in Mycobacterium tuberculosis isolates in Isfahan, Iran.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2020, Volume: 85

    Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Capreomycin; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Genetic Variation; Genotype; Humans; Iran; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant

2020
Drug resistance gene mutations and treatment outcomes in MDR-TB: A prospective study in Eastern China.
    PLoS neglected tropical diseases, 2021, Volume: 15, Issue:1

    Topics: Acetyltransferases; Adult; Amidohydrolases; Antitubercular Agents; Bacterial Proteins; Catalase; China; DNA Gyrase; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Kanamycin; Male; Middle Aged; Multivariate Analysis; Mutation; Mutation Rate; Mycobacterium tuberculosis; Odds Ratio; Ofloxacin; Prospective Studies; Rifampin; Sequence Analysis, DNA; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2021
Use of Whole-Genome Sequencing to Predict
    Microbiology spectrum, 2022, 04-27, Volume: 10, Issue:2

    Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant

2022
Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 121

    Topics: Amikacin; Antitubercular Agents; China; Drug Resistance; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nucleotides; Ofloxacin; Rifampin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomycin; Tuberculosis, Lymph Node

2022
A NiCoT family metal transporter of
    Microbiology (Reading, England), 2022, Volume: 168, Issue:10

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cobalt; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Ethambutol; Gentamicins; Isoleucine; Isoniazid; Kanamycin; Leucine; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Neomycin; Nickel; Norfloxacin; Ofloxacin

2022