ofloxacin and grepafloxacin

ofloxacin has been researched along with grepafloxacin in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	23 (44.23)	18.2507
2000's	25 (48.08)	29.6817
2010's	4 (7.69)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Sasabe, H; Sugiyama, Y; Tsuji, A	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Keserü, GM	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Jia, L; Sun, H	1
Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E	1
Sen, S; Sinha, N	1
Imai, YN; Oiki, S; Ryu, S	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Mitsuhashi, S; Wakebe, H	1
Sanders, CC; Thomson, KS	1
Bale, MJ; Erwin, ME; Jones, RN	1
Hammerschlag, MR; Montalban, G; Roblin, PM	1
Cartwright, FD; Kenny, GE	1
Neumann, T; Patton, M; Reichart, C; Zenilman, JM	1
Hecht, DW; Wexler, HM	1
Goldstein, EJ	1
Barry, AL; Fuchs, PC	1
Barry, AL; Brown, SD; Fuchs, PC	1
Goldsmith, CE; Moore, JE; Murphy, PG	1
Dencer, C; Felmingham, D; Ridgway, GL; Robbins, MJ; Salman, H	1
Deschilder, I; Liekens, K; Lontie, M	1
Hashimoto, Y; Inui, K; Ito, T; Matsuo, Y; Yano, I	1
Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR	1
North, DS	1
Hashimoto, Y; Inui, K; Ito, T; Masuda, S; Yano, I	1
Bébéar, C; Bébéar, CM; Leblanc, F; Renaudin, H; Schaeverbeke, T	1
Hashimoto, K; Minami, T; Owen, K; Takizawa, T; Yamashita, S	1
Fourche, J; Leblanc, F; Maugein, J; Pellegrin, JL; Vacher, S	1
Hooper, DC	2
Amsterdam, D; Hardy, D; Mandell, LA; Rotstein, C	1
Bjarnason, J; Blondeau, JM; Laskowski, R; Stewart, C	1
Hashimoto, Y; Inui, K; Ito, T; Yano, I	1
Hashimoto, Y; Inui, KI; Yamaguchi, H; Yano, I	1
Doern, GV; Ernst, EJ; Klepser, ME; Petzold, CR; Rhomberg, P	1
Johnson, AP; Livermore, DM; Warner, M	1
Asherov, J; Dan, M; Poch, F	1
Adachi, F; Hirota, M; Kamikawa, K; Kanegasaki, S; Nakata, K; Totsu, T; Watanabe, J	1
Ball, P	1
Inui, K; Saito, H; Yamaguchi, H; Yano, I	3
Evans, ME	1
Fujimoto, K; Hirota, M; Kaneki, T; Koizumi, T; Kubo, K; Ogasawara, H; Yamamoto, H; Yamazaki, Y	1
Baumann-Wilschke, I; Rücker, M; Shakibaei, M; Stahlmann, R	1
Fujimura, A; Hakamata, Y; Hirota, M; Hishikawa, S; Kobayashi, E; Miyamoto, G; Mizuta, K	1
Bermejo, MV; Cantón, E; Orero, A; Pemán, J; Velert, MM	1
Dalhoff, A; Shalit, I	1
Di Bonaventura, G; Picciani, C; Piccolomini, R; Spedicato, I	1
Asari, M; Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M; Osaka, Y; Yasuda, S	1

Reviews

6 review(s) available for ofloxacin and grepafloxacin

Article	Year
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23 Suppl 1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Safety; Syndrome	1996
New fluoroquinolone antibiotics. Drug and therapeutics bulletin, 1999, Volume: 37, Issue:1 Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Piperazines; Respiratory Tract Infections	1999
New uses for new and old quinolones and the challenge of resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2 Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Respiratory Tract Infections; Sensitivity and Specificity; Sexually Transmitted Diseases; Urinary Tract Infections	2000
The fluoroquinolones after ciprofloxacin and ofloxacin. Current clinical topics in infectious diseases, 2000, Volume: 20 Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Piperazines; Respiratory Tract Infections; Sexually Transmitted Diseases, Bacterial; Skin Diseases, Bacterial; Urinary Tract Infections	2000
Immunomodulatory effects of quinolones. The Lancet. Infectious diseases, 2003, Volume: 3, Issue:6 Topics: Adjuvants, Immunologic; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Clinical Trials as Topic; Cytokines; Fluoroquinolones; Humans; Immune System; Models, Animal; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2003

Trials

1 trial(s) available for ofloxacin and grepafloxacin

Article	Year
Crossover assessment of serum bactericidal activity of grepafloxacin, ofloxacin and clarithromycin against respiratory pathogens after oral administration to healthy volunteers. International journal of antimicrobial agents, 2001, Volume: 17, Issue:6 Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Blood Bactericidal Activity; Clarithromycin; Cross-Over Studies; Female; Fluoroquinolones; Haemophilus influenzae; Humans; In Vitro Techniques; Klebsiella pneumoniae; Male; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Piperazines; Respiratory Tract Infections; Streptococcus pneumoniae	2001

Article

Year

Crossover assessment of serum bactericidal activity of grepafloxacin, ofloxacin and clarithromycin against respiratory pathogens after oral administration to healthy volunteers.

International journal of antimicrobial agents, 2001, Volume: 17, Issue:6

Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Blood Bactericidal Activity; Clarithromycin; Cross-Over Studies; Female; Fluoroquinolones; Haemophilus influenzae; Humans; In Vitro Techniques; Klebsiella pneumoniae; Male; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Piperazines; Respiratory Tract Infections; Streptococcus pneumoniae

2001

Other Studies

45 other study(ies) available for ofloxacin and grepafloxacin

Article	Year
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:3 Topics: Animals; Anti-Infective Agents; Bile; Biological Transport, Active; Fluoroquinolones; Glucuronates; Glutathione; Hyperbilirubinemia; Male; Piperazines; Quinolones; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley	1998
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel. Bioorganic & medicinal chemistry letters, 2013, Jul-01, Volume: 23, Issue:13 Topics: Anti-Bacterial Agents; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Models, Molecular; Potassium Channel Blockers; Structure-Activity Relationship	2013
Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:10 Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus	1992
Dissociated resistance among fluoroquinolones. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:9 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones	1994
Minimum inhibitory concentration quality-control guidelines for biapenem, DU-6859a, FK-037, levofloxacin, grepafloxacin, and ceftizoxime when using various National Committee for Clinical Laboratory Standards susceptibility test methods. Quality Control S Diagnostic microbiology and infectious disease, 1994, Volume: 19, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ceftizoxime; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quality Control; Quinolones; Reference Values; Spiro Compounds; Thienamycins	1994
In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6 Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones	1994
Susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to a new quinolone, OPC 17116. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:8 Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum	1993
Antibacterial activities of OPC-17116, ofloxacin, and ciprofloxacin against 200 isolates of Neisseria gonorrhoeae. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:10 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Penicillin Resistance; Piperazines; Quinolones; Tetracycline Resistance	1993
In vitro susceptibility of anaerobes to quinolones in the United States. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23 Suppl 1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Quinolones; United States	1996
Antibacterial activities of grepafloxacin, ciprofloxacin, ofloxacin and fleroxacin. Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones	1997
Is Escherichia coli ATCC 25922 useful for monitoring broth microdilution tests of fluoroquinolones? The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:4 Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Reproducibility of Results	1997
Pneumococcal resistance in the UK. The Journal of antimicrobial chemotherapy, 1997, Volume: 40 Suppl A Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Macrolides; Microbial Sensitivity Tests; Northern Ireland; Ofloxacin; Oxacillin; Penicillin Resistance; Penicillins; Piperazines; Pneumococcal Infections; Quinolones; Retrospective Studies; Streptococcus pneumoniae; Tetracycline	1997
The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp. The Journal of antimicrobial chemotherapy, 1997, Volume: 40 Suppl A Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia; Clarithromycin; Dose-Response Relationship, Drug; Doxycycline; Fluoroquinolones; Gram-Negative Bacteria; Legionella; Mycoplasma; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum	1997
In vitro activity of newer quinolones on Streptococcus pneumoniae isolated from outpatients. Acta clinica Belgica, 1998, Volume: 53, Issue:4 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Cephalosporins; Doxycycline; Drug Therapy, Combination; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Outpatients; Penicillin G; Penicillins; Piperazines; Pneumococcal Infections; Quinolones; Roxithromycin; Streptococcus pneumoniae	1998
Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC-PK1. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2 Topics: 4-Chloromercuribenzenesulfonate; Animals; Anti-Infective Agents; Cyclosporine; Epithelial Cells; Fluoroquinolones; Hydrogen-Ion Concentration; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Piperazines; Quinolones; Swine	1998
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin	1999
Common questions about the newer fluoroquinolone antibiotics. The Nurse practitioner, 1999, Volume: 24, Issue:3 Topics: Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Patient Selection; Piperazines; United States; United States Food and Drug Administration	1999
Distribution characteristics of levofloxacin and grepafloxacin in rat kidney. Pharmaceutical research, 1999, Volume: 16, Issue:4 Topics: Animals; Anti-Infective Agents; Carbon Radioisotopes; Cimetidine; Dose-Response Relationship, Drug; Fluoroquinolones; In Vitro Techniques; Kidney Cortex; Kinetics; Levofloxacin; Male; Ofloxacin; p-Aminohippuric Acid; Piperazines; Rats; Rats, Wistar; Tetraethylammonium; Tissue Distribution	1999
In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Doxycycline; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Ofloxacin; Piperazines; Ureaplasma urealyticum	1999
The comparative arthropathy of fluoroquinolones in dogs. Human & experimental toxicology, 1999, Volume: 18, Issue:6 Topics: Animals; Anti-Infective Agents; Body Weight; Ciprofloxacin; Dogs; Eating; Fluoroquinolones; Joint Diseases; Male; Ofloxacin; Piperazines; Synovial Fluid	1999
Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin. The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Macrophages; Microbial Sensitivity Tests; Monocytes; Mycobacterium; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Piperazines; Tuberculosis	1999
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2000
Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms. International journal of antimicrobial agents, 2000, Volume: 14, Issue:1 Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2000
Transepithelial transport of levofloxacin in the isolated perfused rat kidney. Pharmaceutical research, 2000, Volume: 17, Issue:2 Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biological Transport; Carbon Radioisotopes; Cimetidine; Coloring Agents; Enzyme Inhibitors; Epithelial Cells; Evans Blue; Fluoroquinolones; In Vitro Techniques; Inulin; Kidney; Levofloxacin; Male; Ofloxacin; p-Aminohippuric Acid; Perfusion; Piperazines; Rats; Rats, Wistar; Tetraethylammonium; Urine	2000
Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line caco-2. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Anti-Infective Agents; Biological Transport; Caco-2 Cells; Cyclosporine; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Intestinal Mucosa; Levofloxacin; Metabolic Clearance Rate; Ofloxacin; Piperazines	2000
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae; Time Factors	2001
Activity of moxifloxacin and other quinolones against pneumococci resistant to first-line agents, or with high-level ciprofloxacin resistance. International journal of antimicrobial agents, 2001, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae	2001
Comparison of antimycobacterial activity of grepafloxacin against Mycobacterium avium with that of levofloxacin: accumulation of grepafloxacin in human macrophages. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2001, Volume: 7, Issue:1 Topics: Anti-Infective Agents; Antitubercular Agents; Biological Transport; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Piperazines	2001
Safety of the new fluoroquinolones compared with ciprofloxacin. Journal of chemotherapy (Florence, Italy), 2000, Volume: 12 Suppl 1 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines	2000
Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. European journal of pharmacology, 2001, Nov-23, Volume: 431, Issue:3 Topics: Adenosine Triphosphate; Anti-Infective Agents; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Chlorides; Cyclosporine; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Levofloxacin; Ofloxacin; Piperazines	2001
Determining the frequency of resistance of Streptococcus pneumoniae to ciprofloxacin, levofloxacin, trovafloxacin, grepafloxacin, and gemifloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:12 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Streptococcus pneumoniae	2001
Lung tissue distribution after intravenous administration of grepafloxacin: comparative study with levofloxacin. Japanese journal of pharmacology, 2002, Volume: 88, Issue:1 Topics: Animals; Anti-Infective Agents; Epithelium; Fluoroquinolones; Infusions, Intravenous; Levofloxacin; Lung; Lymph; Molecular Structure; Ofloxacin; Piperazines; Pulmonary Circulation; Sheep; Time Factors	2002
Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3 Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Availability; Cyclosporine; Enzyme Inhibitors; Fluoroquinolones; Genes, MDR; Intestinal Mucosa; Kidney; Levofloxacin; Liver; Male; Mice; Mice, Knockout; Ofloxacin; Piperazines; Rats; Tissue Distribution	2002
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones. Archives of toxicology, 2002, Volume: 75, Issue:11-12 Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Limb Buds; Magnesium; Male; Mice; Mice, Inbred Strains; Ofloxacin; Piperazines; Pregnancy; Quinolones	2002
Fluoroquinolone concentrations in plasma, urine, and bile after oral administration in rats with renal failure: useful technique for long-term bile collection. Journal of medicine, 2001, Volume: 32, Issue:5-6 Topics: Administration, Oral; Animals; Anti-Infective Agents; Bile; Blood Urea Nitrogen; Fluoroquinolones; Levofloxacin; Male; Ofloxacin; Osmolar Concentration; Piperazines; Rats; Rats, Wistar; Reference Values; Renal Insufficiency; Specimen Handling	2001
[Influence of ion pump-inhibiting drugs on the accumulation of ofloxacin and grepafloxacin in human polymorphonuclear leukocytes]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2002, Volume: 15, Issue:4 Topics: Anti-Infective Agents; Calcium Channel Blockers; Digoxin; Enzyme Inhibitors; Fluoroquinolones; Humans; Ion Pumps; Neutrophils; Ofloxacin; Omeprazole; Piperazines; Verapamil	2002
Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rats. Pharmaceutical research, 2004, Volume: 21, Issue:2 Topics: Acute Kidney Injury; Animals; Anti-Infective Agents; Antineoplastic Agents; Bile Ducts; Biological Availability; Blotting, Western; Caco-2 Cells; Ciprofloxacin; Cisplatin; Duodenum; Fluoroquinolones; Humans; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Piperazines; Rats; Rats, Wistar; Time Factors	2004
E-test method for detecting antibiotic synergy against Pseudomonas aeruginosa from neutropenic patients: a cost-effective approach. The new microbiologica, 2004, Volume: 27, Issue:3 Topics: Anemia; Anti-Bacterial Agents; Cefotaxime; Ceftriaxone; Cost-Benefit Analysis; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Hematologic Neoplasms; Humans; Levofloxacin; Microbial Sensitivity Tests; Neutropenia; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections	2004
The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo. International journal of pharmaceutics, 2008, Mar-03, Volume: 351, Issue:1-2 Topics: Biological Transport; Carnitine; Cell Line, Tumor; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Ofloxacin; Organic Cation Transport Proteins; Piperazines; Placenta; Sodium; Solute Carrier Family 22 Member 5	2008