ofloxacin and gemifloxacin

ofloxacin has been researched along with gemifloxacin in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	32 (76.19)	29.6817
2010's	10 (23.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Amsterdam, D; Hardy, D; Mandell, LA; Rotstein, C	1
Edmond, M; Heinemann, B; Seifert, H; Wisplinghoff, H	1
Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H	1
Ferraro, MJ; Jorgensen, JH; Swenson, JM; Tenover, FC; Weigel, LM; Whitney, CG	1
Bouchillon, SK; Butler, DL; Hoban, DJ; Johnson, JL; Karlowsky, JA; Miller, LA; Poupard, JA	1
Hollauer, K; Kirchbauer, D; Naber, KG; Witte, W	1
Doyle, E; Edelstein, MA; Edelstein, PH; Shinzato, T	1
Boos, M; Fluit, AC; Hafner, D; Jagusch, H; Mayer, S; Schmitz, FJ; Verhoef, J	1
Bygate, EA; Fairless, AJ; Hammer, M; Kinzig-Schippers, M; Machka, K; Naber, CK; Naber, KG; Sauber, C; Sörgel, F	1
Rossi, C; Sternon, J	1
Bouchillon, SK; Butler, DL; Hoban, DJ; Johnson, JL; Miller, LA; Poupard, JA; Zhanel, GG	1
Evans, ME	1
Biedenbach, DJ; Jones, RN	1
Cheong, HJ; Choo, YS; Kang, MW; Kim, WJ; Kim, YS; Lee, KW; Park, YJ; Woo, JH; Yong, DE	1
Bowker, KE; MacGowan, AP	1
Firsov, AA; Lubenko, IY; Portnoy, YA; Vostrov, SN; Zinner, SH	1
Aguilar, L; García-Calvo, G; García-Olmos, M; Giménez, MJ; Parra, A; Ponte, C; Soriano, F	1
Aguilar, L; Garcia-Mendez, E; Jiménez De Anta, MT; Marco, F; Mensa, J; Ruiz, J; Sierra, JM; Vila, J	1
Leggett, J; Saravolatz, LD	1
Garrison, MW; Madaras-Kelly, KJ; Schimmels, JA	1
Martinez, FJ	1
Fogarty, C; Fulambarker, A; Sethi, S	1
Aguilar, L; Alkorta, M; Giménez, MJ; Pérez-Trallero, E; Vicente, D	1
Baltch, AL; Bopp, LH; Michelsen, PB; Ritz, WJ; Smith, RP	1
Cabeza, JG; Hernandez, J; Llagostera, M; Mensa, J; Montero, T; Ruiz Chaler, M; Sierra, JM; Vila, J	1
Bae, CS; Bae, JG; Jeong, MJ; Kim, JC; Kim, SG; Kim, SH; Kim, YS; Lim, SC; Oh, DM	1
Appelbaum, PC; Bozdogan, B; Choi, DR; Credito, K; Dewasse, B; Kosowska-Shick, K; Lin, G; McGhee, P; Pankuch, GA; Ryu, JM	1
Blondeau, JM; Blondeau, LD; Borsos, S; Hesje, C	1
Adam, HJ; Baudry, TJ; Hoban, CJ; Hoban, DJ; Laing, NM; Nichol, KA; Schurek, KN; Zhanel, GG	1
Bast, DJ; de Azavedo, JC; Dresser, L; Duncan, CL; Low, DE; Mandell, LA; Walker, SE	1
Kaatz, GW; LaPlante, KL; Lodise, TP; Rybak, MJ; Tsuji, B	1
Appelbaum, PC; Clark, CL; Ednie, LM; Kosowska-Shick, K	1
Appelbaum, PC; Credito, K; Kosowska-Shick, K; McGhee, P; Pankuch, GA	1
Hsueh, PR; Lee, PI; Yang, JC	1
Schafer, KR; Wispelwey, B	1
Chen, H; Jiang, H; Liu, T; Song, Z; Wu, X; Xu, Y; Yang, L; Yue, W	1
Hsueh, PR; Ko, WC; Liao, CH; Lu, JJ	1
Cass, QB; Denadai, M	1

Reviews

4 review(s) available for ofloxacin and gemifloxacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019
[Third and fourth generation fluoroquinolones]. Revue medicale de Bruxelles, 2001, Volume: 22, Issue:5 Topics: Administration, Oral; Anti-Infective Agents; Aza Compounds; Belgium; Biological Availability; Drug Monitoring; Drug Resistance; Fluoroquinolones; Gemifloxacin; Humans; Intestinal Absorption; Levofloxacin; Moxifloxacin; Naphthyridines; Ofloxacin; Patient Selection; Pneumococcal Infections; Quinolines; Respiratory Tract Infections; Streptococcus pneumoniae; Time Factors; Treatment Outcome	2001
Fluoroquinolones in the management of community-acquired pneumonia in primary care. Expert review of anti-infective therapy, 2010, Volume: 8, Issue:11 Topics: Ambulatory Care; Anti-Bacterial Agents; Aza Compounds; Clinical Trials as Topic; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumonia, Bacterial; Primary Health Care; Quinolines; Streptococcus pneumoniae	2010

Trials

2 trial(s) available for ofloxacin and gemifloxacin

Article	Year
Urinary excretion and bactericidal activities of gemifloxacin and ofloxacin after a single oral dose in healthy volunteers. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:12 Topics: Adolescent; Adult; Anti-Infective Agents; Calibration; Cross-Over Studies; Female; Fluoroquinolones; Gemifloxacin; Humans; Hydrogen-Ion Concentration; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quality Control; Urine	2001
A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. Respiratory medicine, 2004, Volume: 98, Issue:8 Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Male; Middle Aged; Naphthyridines; Ofloxacin; Treatment Outcome	2004

Article

Year

Urinary excretion and bactericidal activities of gemifloxacin and ofloxacin after a single oral dose in healthy volunteers.

Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:12

Topics: Adolescent; Adult; Anti-Infective Agents; Calibration; Cross-Over Studies; Female; Fluoroquinolones; Gemifloxacin; Humans; Hydrogen-Ion Concentration; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quality Control; Urine

2001

A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis.

Respiratory medicine, 2004, Volume: 98, Issue:8

Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Male; Middle Aged; Naphthyridines; Ofloxacin; Treatment Outcome

2004

Other Studies

36 other study(ies) available for ofloxacin and gemifloxacin

Article	Year
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2000
Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8 Topics: Acinetobacter; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines	2000
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates. Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:2 Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin	2000
Activities of clinafloxacin, gatifloxacin, gemifloxacin, and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Streptococcus pneumoniae	2000
A comparative In vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America. The Gemifloxacin Surveillance Study Research Group. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Adolescent; Adult; Anti-Infective Agents; Drug Resistance, Microbial; Europe; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Naphthyridines; North America; Ofloxacin; South America; Streptococcus pneumoniae	2000
In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections. International journal of antimicrobial agents, 2000, Volume: 16, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Klebsiella; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Urinary Tract Infections	2000
In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:8 Topics: Animals; Anti-Infective Agents; Area Under Curve; Azithromycin; Body Weight; Fluoroquinolones; Gemifloxacin; Guinea Pigs; Half-Life; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Lung; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Survival Rate	2001
Propensity of fluoroquinolones with different moieties at position 8 to cause resistance development in clinical isolates of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Streptococcus pneumoniae	2001
Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:11 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Europe; Fluoroquinolones; Gemifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin	2001
Determining the frequency of resistance of Streptococcus pneumoniae to ciprofloxacin, levofloxacin, trovafloxacin, grepafloxacin, and gemifloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:12 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Streptococcus pneumoniae	2001
Evaluation of in vitro susceptibility testing criteria for gemifloxacin when tested against Haemophilus influenzae strains with reduced susceptibility to ciprofloxacin and ofloxacin. Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:4 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin	2002
In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea. Journal of Korean medical science, 2002, Volume: 17, Issue:6 Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Haemophilus influenzae; Korea; Levofloxacin; Microbial Sensitivity Tests; Moraxella; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2002
Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Anti-Infective Agents; Area Under Curve; Colony Count, Microbial; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Half-Life; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Mutation; Naphthyridines; Ofloxacin; Streptococcus pneumoniae	2003
Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters. Chemotherapy, 2002, Volume: 48, Issue:6 Topics: Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Time Factors	2002
Efficacy and pharmacodynamics of gemifloxacin versus levofloxacin in guinea pig pneumococcal pneumonia induced by strains with decreased ciprofloxacin susceptibility. International journal of antimicrobial agents, 2003, Volume: 21, Issue:6 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Guinea Pigs; Levofloxacin; Lung; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis	2003
In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene. International journal of antimicrobial agents, 2003, Volume: 22, Issue:1 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Genes, Bacterial; Gonorrhea; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Nalidixic Acid; Naphthyridines; Neisseria gonorrhoeae; Ofloxacin; Quinolines	2003
Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Nov-01, Volume: 37, Issue:9 Topics: Aza Compounds; Bacteroides fragilis; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2003
In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4 Topics: Analysis of Variance; Aza Compounds; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Pharmacogenetics; Pneumococcal Infections; Probability; Quinolines; Reference Values; Regression Analysis; Sensitivity and Specificity; Streptococcus pneumoniae	2003
Monotherapy versus dual therapy for community-acquired pneumonia in hospitalized patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, May-15, Volume: 38 Suppl 4 Topics: Anti-Infective Agents; Aza Compounds; Community-Acquired Infections; Doxycycline; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Hospitalization; Humans; Levofloxacin; Macrolides; Moxifloxacin; Naphthyridines; Ofloxacin; Outcome Assessment, Health Care; Pneumonia, Bacterial; Quinolines; Retrospective Studies	2004
In vivo activity of gemifloxacin, moxifloxacin and levofloxacin against pneumococci with gyrA and parC point mutations in a sepsis mouse model measured with the all or nothing mortality end-point. International journal of antimicrobial agents, 2005, Volume: 25, Issue:2 Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Levofloxacin; Mice; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Point Mutation; Quinolines; Sepsis; Streptococcus pneumoniae; Treatment Outcome	2005
Antibacterial activities of gemifloxacin, levofloxacin, gatifloxacin, moxifloxacin and erythromycin against intracellular Legionella pneumophila and Legionella micdadei in human monocytes. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:1 Topics: Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Drug; Erythromycin; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Legionella; Legionella pneumophila; Levofloxacin; Microbial Sensitivity Tests; Monocytes; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines	2005
The selection of resistance to and the mutagenicity of different fluoroquinolones in Staphylococcus aureus and Streptococcus pneumoniae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:9 Topics: Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Moxifloxacin; Mutagenicity Tests; Naphthyridines; Ofloxacin; Quinolines; Selection, Genetic; Staphylococcus aureus; Streptococcus pneumoniae	2005
Ultrastructural changes of the gemifloxacin on Achilles tendon in immature rats: comparison with those of ciproxacin and ofloxacin. Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:4 Topics: Achilles Tendon; Animals; Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Male; Microscopy, Electron, Transmission; Naphthyridines; Ofloxacin; Rats; Rats, Sprague-Dawley	2006
Antipneumococcal activity of DW-224a, a new quinolone, compared to those of eight other agents. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Azithromycin; Cefuroxime; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genes, Bacterial; Levofloxacin; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2006
Application of two methods to determine killing of Streptococcus pneumoniae by various fluoroquinolones. Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:4 Topics: Anti-Bacterial Agents; Aza Compounds; Cells, Cultured; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2006
Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aza Compounds; Bacterial Proteins; Canada; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Serotyping; Streptococcus pneumoniae	2007
Short-course therapy of gemifloxacin effective against pneumococcal pneumonia in mice. Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:6 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Body Temperature; Colony Count, Microbial; Disease Models, Animal; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Lung; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Mutation, Missense; Naphthyridines; Ofloxacin; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Analysis; Survival Rate; Time Factors; Treatment Outcome	2006
Fluoroquinolone resistance in Streptococcus pneumoniae: area under the concentration-time curve/MIC ratio and resistance development with gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Area Under Curve; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae	2007
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2007
Comparative study of the mutant prevention concentrations of moxifloxacin, levofloxacin, and gemifloxacin against pneumococci. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Anti-Bacterial Agents; Aza Compounds; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Polymerase Chain Reaction; Quinolines; Streptococcus pneumoniae	2010
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010, Volume: 29, Issue:11 Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline	2010
Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4 Topics: Animals; Anti-Infective Agents, Local; Colony Count, Microbial; Conjunctival Diseases; Cornea; Eye; Female; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Keratitis; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus	2012
Characterizations of clinical isolates of clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin (OPT-80) and rifaximin: a multicenter study in Taiwan. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:7 Topics: Anti-Infective Agents; Aza Compounds; Bacterial Proteins; Clostridioides difficile; Fluoroquinolones; Gemifloxacin; Glycosides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Rifamycins; Rifaximin; Taiwan; Vancomycin	2012
Simultaneous determination of fluoroquinolones in environmental water by liquid chromatography-tandem mass spectrometry with direct injection: A green approach. Journal of chromatography. A, 2015, Oct-30, Volume: 1418 Topics: Anti-Bacterial Agents; Brazil; Chromatography, Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Fresh Water; Gemifloxacin; Green Chemistry Technology; Moxifloxacin; Naphthyridines; Norfloxacin; Ofloxacin; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical	2015