ofloxacin and fleroxacin

ofloxacin has been researched along with fleroxacin in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (24.29)	18.7374
1990's	38 (54.29)	18.2507
2000's	10 (14.29)	29.6817
2010's	4 (5.71)	24.3611
2020's	1 (1.43)	2.80

Authors

Authors	Studies
Cohen, MA; Domagala, JM; Mailloux, GB; Roland, GE; Suto, MJ	1
Domagala, JM; Hanna, LD; Heifetz, CL; Hutt, MP; Mich, TF; Sanchez, JP; Solomon, M	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Jolivette, LJ; Nagilla, R; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Hammerschlag, MR; Hyman, CL; Roblin, PM	1
Jones, RN	1
Bartlett, RC; Mazens-Sullivan, MF; McCarter, YS	1
Conejo, MC; García, I; Pascual, A; Perea, EJ	1
Barry, AL; Fuchs, PC	2
Saito, H; Sato, K; Tomioka, H	1
Gocke, E	1
Kamisaka, K; Kawahara, S; Kibata, M; Matsuyama, T; Mishima, Y; Nagare, J; Nakada, H; Tada, A; Yoshimoto, S	1
Cullmann, W; Dechène, M; Leying, H	1
Boeckk, M; Borner, K; Deppermann, N; Höffken, G; Koeppe, P; Lode, H	1
Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B	1
Daschner, F; Kropec, A	1
Aubert, G; Denis, M; Dorche, G; Loboguerrero, M; Lucht, F; Puech, C	1
Akalin, HE; Akyön, Y; Diker, S; Gür, D; Hasçelik, G	1
Aoyama, H; Hirai, K; Hosaka, M; Irikura, T; Niwata, Y; Oomori, Y; Suzue, S	1
Fass, RJ; Helsel, VL	1
Habiyaremye, I; Vandepitte, J; Verbist, L	1
Braveny, I; Machka, K	1
Verbist, L	1
Appelbaum, PC; Spangler, SK; Tamarree, T	1
Krausse, R; Ullmann, U	1
Andrews, JM; Ashby, JP; Matthews, RS; Wise, R	1
Benonisen, E; Digranes, A; Salveson, A; Zahm, F	1
Cullmann, W; Dechène, M; Stieglitz, M	1
Ritzerfeld, W	1
Fernandes, PB; Swanson, RN	1
Nagayama, A; Nakao, T; Taen, H	1
Beskid, G; Prosser, BL	2
Cormican, MG; Jones, RN; Marshall, SA	1
Arman, D; Tural, D; Willke, A	1
Haen, E; Kurz, H; Przybilla, B; Tiefenbacher, EM	1
Griffiths, NM; Hirst, BH; Simmons, NL	1
Coll, R; Esteve, M; Garcia, J; Gargallo-Viola, D; Guinea, J; Pares, M; Robert, M; Roser, R; Tudela, E; Xicota, MA	1
Norte, V; Panchal, S; Piddock, LJ	1
Naber, KG; Sigl, G	1
Cormican, MG; Jones, RN	1
Coll, R; Mirelis, B; Miró, E; Navarro, F; Prats, G; Xicota, MA	1
Kubo, S; Kumazawa, J; Matsumoto, T; Nagafuji, T; Takahashi, K	1
Dobias, J; Doupovcová, M; Ebringer, L; Krajcovic, J; Lahitová, N; Polónyi, J	1
Cheung, MM; Ho, NK; Kam, KM; Wong, PW	1
Ballesta, S; García, I; Pascual, A; Perea, EJ	1
Klecak, G; Urbach, F; Urwyler, H	1
Forbes, PD; Mäkinen, M; Stenbäck, F	1
Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K	1
Dobias, J; Ebringer, L; Krajcovic, J; Polónyi, J	1
Beil, WJ; Georgopoulos, A; Graninger, W; Griesmacher, A; Hlousek, M; Robibaro, B; Schaumann, R; Vorbach, H; Weigel, G	1
Förster, C; Günther, T; Lozo, E; Merker, HJ; Schwabe, R; Stahlmann, R; Vormann, J; Zippel, U	1
Armbruster, C; Georgopoulos, A; Graninger, W; Griesmacher, A; Hlousek, M; Reiter, M; Robibaro, B; Vorbach, H; Weigel, G	1
Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J	1
Barbosa, J; Bergés, R; Sanz-Nebot, V	1
Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I	1
Gericke, C; Metzner, S; Rahm, U; Stahlmann, R; Thiel, R	1
Chen, BY; Cheng, NN; Li, MH; Wang, YM; Zhang, LR	1
Araake, M; Hara, T; Nishino, T; Watabe, H	1
Fan, Y; Gan, X; Li, S; Qin, W	1
Baeyens, WR; Fei, G; He, L; Huang, C; Ouyang, J; Wang, Y	1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M	1
Alaboud, M; Bulatov, A; Korolev, D; Lebedinets, S; Moskvin, L; Osmolovskaya, O; Postnov, V; Vakh, C	1
Gao, M; Li, H; Li, W; Pan, X; Shan, L; Tian, H; Wang, J	1

Reviews

1 review(s) available for ofloxacin and fleroxacin

Article	Year
Pharmacokinetics of quinolones in renal insufficiency. The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl B Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones	1990

Trials

1 trial(s) available for ofloxacin and fleroxacin

Article	Year
Fleroxacin versus ofloxacin in patients with complicated urinary tract infection: a controlled clinical study. The American journal of medicine, 1993, Mar-22, Volume: 94, Issue:3A Topics: Adult; Aged; Aged, 80 and over; Female; Fleroxacin; Humans; Male; Middle Aged; Ofloxacin; Prospective Studies; Urinary Tract Infections	1993

Other Studies

68 other study(ies) available for ofloxacin and fleroxacin

Article	Year
Fluoroquinolones: relationships between structural variations, mammalian cell cytotoxicity, and antimicrobial activity. Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25 Topics: Animals; Anti-Infective Agents; Cricetinae; Cricetulus; Fluoroquinolones; Microbial Sensitivity Tests; Structure-Activity Relationship	1992
New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay. Journal of medicinal chemistry, 1986, Volume: 29, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; DNA, Bacterial; DNA, Superhelical; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Plasmids; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1986
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
In vitro activities of five quinolones against Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:3 Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1992
In vitro evaluation of E-4695, a new fluoro-naphthyridine. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:2 Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones	1992
The comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents. Chemotherapy, 1992, Volume: 38, Issue:5 Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1992
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:11 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones	1991
Cross-resistance and cross-susceptibility between fluoroquinolone agents. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:12 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Quinolones	1991
Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria. Tubercle, 1991, Volume: 72, Issue:3 Topics: Animals; Disease Models, Animal; Female; Fleroxacin; Leprosy; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin	1991
Mechanism of quinolone mutagenicity in bacteria. Mutation research, 1991, Volume: 248, Issue:1 Topics: Anti-Infective Agents; Blotting, Southern; Ciprofloxacin; DNA Topoisomerases, Type II; Enrofloxacin; Escherichia coli; Fleroxacin; Fluoroquinolones; Genes, Bacterial; Mutation; Novobiocin; Ofloxacin; Oxolinic Acid; Quinolones; Salmonella	1991
[In vitro activities of newly developed quinolones, fleroxacin, lomefloxacin and sparfloxacin against Mycobacterium tuberculosis]. Kekkaku : [Tuberculosis], 1991, Volume: 66, Issue:6 Topics: Anti-Infective Agents; Antitubercular Agents; Fleroxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones	1991
Role of the outer membrane for quinolone resistance in enterobacteria. Chemotherapy, 1990, Volume: 36, Issue:1 Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Escherichia coli; Fleroxacin; Lipopolysaccharides; Nalidixic Acid; Ofloxacin; Serratia marcescens; Species Specificity	1990
Quinolone pharmacokinetics and metabolism. The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl B Topics: Administration, Oral; Anti-Infective Agents; Biological Availability; Biotransformation; Ciprofloxacin; Enoxacin; Fleroxacin; Half-Life; Humans; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin	1990
In vitro activity of fleroxacin and 6 other antimicrobials against Acinetobacter anitratus. Chemotherapy, 1989, Volume: 35, Issue:5 Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Enoxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Ofloxacin; Tobramycin	1989
[Activity of 5 fluoroquinolones on hospital Gram-negative bacilli with different sensitivities to pefloxacin]. Pathologie-biologie, 1989, Volume: 37, Issue:8 Topics: Anti-Infective Agents; Ciprofloxacin; Citrobacter; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pefloxacin; Pseudomonas aeruginosa; Serratia marcescens	1989
[In vitro susceptibility of Campylobacter jejuni and Campylobacter coli to quinolone antibiotics]. Mikrobiyoloji bulteni, 1989, Volume: 23, Issue:3 Topics: Anti-Infective Agents; Campylobacter; Campylobacter jejuni; Ciprofloxacin; Feces; Fleroxacin; Humans; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin	1989
In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative. Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:6 Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Male; Mice; Mice, Inbred ICR; Norfloxacin; Ofloxacin; Oxazines; Pneumonia; Quinolines; Urinary Tract Infections	1986
In vitro activity of RO 23-6240 (AM-833): a new fluoroquinolone. Diagnostic microbiology and infectious disease, 1987, Volume: 6, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin	1987
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria]. Pathologie-biologie, 1987, Volume: 35, Issue:5 Pt 2 Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica	1987
Comparative in vitro activity of RO 23-6240 (fleroxacin), a new 4-quinolone derivative. European journal of clinical microbiology, 1987, Volume: 6, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Enterobacteriaceae; Enterococcus faecalis; Fleroxacin; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Staphylococcus	1987
Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone. The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines	1987
Susceptibility of 310 nonfermentative gram-negative bacteria to aztreonam, carumonam, ciprofloxacin, ofloxacin and fleroxacin. Chemotherapy, 1988, Volume: 34, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Ofloxacin; Oxazines	1988
Comparative in vitro activity of fleroxacin (RO 23-6240) against Ureaplasma urealyticum and Mycoplasma hominis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1988, Volume: 7, Issue:1 Topics: Anti-Bacterial Agents; Ciprofloxacin; Doxycycline; Fleroxacin; Humans; Leucomycins; Mycoplasma; Ofloxacin; Oxazines; Ureaplasma	1988
In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5 Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Blood Proteins; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Ofloxacin; Oxazines; Protein Binding; Pseudomonas aeruginosa; Quinolines; Quinolones; Staphylococcus; Streptococcus; Trimethoprim	1988
In vitro studies of fleroxacin (Ro 23-6240), a new trifluorinated quinolone derivative. Chemotherapy, 1988, Volume: 34, Issue:5 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fleroxacin; Hydrogen-Ion Concentration; Ofloxacin	1988
[Comparative antibacterial activity of fleroxacin: selection frequencies and outer membrane proteins of resistant mutants]. Immunitat und Infektion, 1988, Volume: 16, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Outer Membrane Proteins; Ciprofloxacin; Drug Combinations; Drug Resistance, Microbial; Escherichia coli; Fleroxacin; Humans; Mutation; Ofloxacin; Serratia marcescens; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
Comparative studies of fleroxacin and ofloxacin in experimental pyelonephritis. The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl D Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Fleroxacin; Half-Life; Klebsiella; Ofloxacin; Pseudomonas aeruginosa; Pyelonephritis; Rats; Rats, Inbred Strains	1988
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:6 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones	1988
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones	1988
Multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1995
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin). Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds	1995
In vitro activity of eight antibiotics against Salmonella and Shigella species. European journal of epidemiology, 1994, Volume: 10, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fleroxacin; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Salmonella; Shigella; Trimethoprim, Sulfamethoxazole Drug Combination	1994
Photodegradation of some quinolones used as antimicrobial therapeutics. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:4 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Light; Mass Spectrometry; Ofloxacin; Photochemistry; Spectrophotometry, Ultraviolet; Ultraviolet Rays	1994
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway? The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2 Topics: Biological Transport; Carbon Radioisotopes; Cells, Cultured; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Humans; Intestinal Mucosa; Norfloxacin; Ofloxacin; Pefloxacin; Quinolizines	1994
A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers. The American journal of medicine, 1993, Mar-22, Volume: 94, Issue:3A Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1993
In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:4 Topics: Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fleroxacin; Fluoroquinolones; Horses; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1993
Comparison of the mechanism of action and resistance of two new fluoroquinolones, rufloxacin and MF961 with those of ofloxacin and fleroxacin in gram-negative and gram-positive bacteria. The Journal of antimicrobial chemotherapy, 1993, Volume: 31, Issue:6 Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mutation; Ofloxacin; Quinolones; Rec A Recombinases	1993
Cross-resistance analysis for clinafloxacin compared with ciprofloxacin, fleroxacin, ofloxacin, and sparfloxacin using a predictor panel of ciprofloxacin-resistant bacteria. The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:2 Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1995
In vitro activity of E-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin. Drugs under experimental and clinical research, 1995, Volume: 21, Issue:4 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Ofloxacin; Quinolones	1995
Effect of inhibitors of protein kinase C on enhanced superoxide production of human leucocytes by ofloxacin and fleroxacin. Drugs, 1995, Volume: 49 Suppl 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Anti-Infective Agents; Enzyme Inhibitors; Fleroxacin; Humans; In Vitro Techniques; Isoquinolines; Luminescent Measurements; Neutrophils; Ofloxacin; Piperazines; Protein Kinase C; Staurosporine; Superoxides	1995
Tetracycline reduces fluoroquinolones-induced bleaching of Euglena gracilis. Mutation research, 1996, Volume: 340, Issue:2-3 Topics: Animals; Darkness; Euglena gracilis; Fleroxacin; Light; Ofloxacin; Salmonella typhimurium; Spectrophotometry; Tetracycline	1996
Detection of quinolone-resistant Neisseria gonorrhoeae. Journal of clinical microbiology, 1996, Volume: 34, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Reference Standards	1996
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells]. Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14, Issue:8 Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature	1996
Fluoroquinolone antibacterials enhance UVA-induced skin tumors. Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays	1997
Quinolone antibacterials: a new class of photochemical carcinogens. Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3 Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms	1997
Antibacterial activities of grepafloxacin, ciprofloxacin, ofloxacin and fleroxacin. Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones	1997
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones. European journal of haematology, 1997, Volume: 58, Issue:2 Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation	1997
Influence of tetracyclines or cetylpyridinium bromide on activity of fluoroquinolones in Euglena gracilis. Arzneimittel-Forschung, 1997, Volume: 47, Issue:5 Topics: Animals; Anti-Infective Agents; Cetylpyridinium; Doxycycline; Euglena gracilis; Fleroxacin; Ofloxacin; Spectrophotometry, Ultraviolet; Tetracycline; Tetracyclines	1997
Endothelial cell compatibility of fluoroquinolone solutions for intravenous use. International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Anti-Infective Agents; Cell Survival; Cells, Cultured; Ciprofloxacin; Endothelium, Vascular; Epoprostenol; Firefly Luciferin; Fleroxacin; Humans; Injections, Intravenous; Luciferases; Ofloxacin; Radioimmunoassay; Thromboxane A2; Umbilical Veins	1997
Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics. Archives of toxicology, 1997, Volume: 72, Issue:1 Topics: Age Factors; Animals; Anti-Infective Agents; Calcium; Cartilage; Ciprofloxacin; Contraindications; Female; Fleroxacin; Joint Diseases; Knee Joint; Magnesium; Magnesium Deficiency; Male; Ofloxacin; Rats; Rats, Wistar	1997
Endothelial purine content. An alternative model for testing antibiotic solutions for intravenous use. Advances in experimental medicine and biology, 1998, Volume: 431 Topics: Adenosine Triphosphate; Anti-Infective Agents; Cell Survival; Cells, Cultured; Ciprofloxacin; Drug Evaluation, Preclinical; Endothelium, Vascular; Epoprostenol; Fleroxacin; Humans; Ofloxacin; Solutions; Thromboxane A2; Umbilical Veins	1998
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures. Archives of toxicology, 1998, Volume: 72, Issue:7 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones	1998
Retention behaviour of quinolone derivatives in high-performance liquid chromatography. Effect of pH and evaluation of ionization constants. Journal of chromatography. A, 1998, Oct-09, Volume: 823, Issue:1-2 Topics: Acetonitriles; Anti-Infective Agents; Chromatography, High Pressure Liquid; Enoxacin; Fleroxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Osmolar Concentration; Potentiometry; Quinolizines; Quinolones; Thermodynamics; Water	1998
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation. Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays	1999
Effects of fluoroquinolones on the locomotor activity in rats. Archives of toxicology, 2001, Volume: 75, Issue:1 Topics: Administration, Oral; Age Factors; Animals; Anti-Infective Agents; Body Weight; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Fleroxacin; Fluoroquinolones; Locomotion; Male; Naphthyridines; Ofloxacin; Photic Stimulation; Rats; Rats, Wistar; Time Factors	2001
Inhibition by fluoroquinolones of K(+) currents in rat dissociated hippocampal neurons. European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3 Topics: Animals; Dose-Response Relationship, Drug; Fleroxacin; Fluoroquinolones; Hippocampus; Levofloxacin; Membrane Potentials; Neurons; Ofloxacin; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley	2003
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones	2002
A rapid CE-potential gradient detection method for determination of quinolones. Electrophoresis, 2007, Volume: 28, Issue:22 Topics: Animals; Electrophoresis, Capillary; Enoxacin; Fleroxacin; Fluoroquinolones; Methods; Milk; Ofloxacin; Oxazines; Quinolones	2007
Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive. Talanta, 2009, Mar-15, Volume: 77, Issue:5 Topics: Buffers; Electrophoresis, Capillary; Fleroxacin; Fluoroquinolones; Gatifloxacin; Nanoparticles; Ofloxacin; Oxazines; Quinolones; Silicon Dioxide	2009
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures	2009
An automated magnetic dispersive micro-solid phase extraction in a fluidized reactor for the determination of fluoroquinolones in baby food samples. Analytica chimica acta, 2018, Feb-25, Volume: 1001 Topics: Animals; Anti-Bacterial Agents; Cattle; Chickens; Chromatography, High Pressure Liquid; Equipment Design; Fleroxacin; Flow Injection Analysis; Fluoroquinolones; Food Contamination; Humans; Infant; Infant Food; Limit of Detection; Magnetics; Meat; Norfloxacin; Ofloxacin; Solid Phase Microextraction; Turkey	2018
Association between fluoroquinolone exposure and children's growth and development: A multisite biomonitoring-based study in northern China. Environmental research, 2022, Volume: 214, Issue:Pt 2 Topics: Animals; Anti-Bacterial Agents; Biological Monitoring; Child; China; Ciprofloxacin; Enrofloxacin; Fleroxacin; Fluoroquinolones; Humans; Obesity; Ofloxacin; Overweight	2022