ofloxacin and eye

ofloxacin has been researched along with eye in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's8 (26.67)18.2507
2000's15 (50.00)29.6817
2010's6 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adenis, JP; Chauvin, M; Denis, F; Mounier, M; Ploy, MC1
Miyao, M; Okazaki, O; Ooishi, M1
Akers, P; Borrmann, LR; Bosso, JA; Frank, J; Jensen, HG; Osato, MS; Trousdale, MD1
Hayakawa, H; Hayashi, K; Ishikura, H; Nakafuku, K; Nakajima, Y; Oishi, M; Takano, Y1
Gatti, G; Panozzo, G1
Jin, Y; Mochizuki, K; Ohkubo, S; Okamura, Y; Tanahashi, T; Tanaka, M; Torisaki, M; Yamashita, Y1
Akkan, AG; Gök, A; Mutlu, I; Ozüner, Z; Ozyazgan, S; Pekel, H; Senses, V; Yigit, U1
Kurata, T; Yasuhara, H1
Basci, N; Bozkurt, A; Ilker, SS; Inan, UU; Kortunay, S; Kurt, E; Oztürk, F1
Burgalassi, S; Chetoni, P; Di Colo, G; Fiaschi, MP; Saettone, MF; Zambito, Y1
Amin, PD; Cardoza, RM; Srividya, B1
Roberts, C1
Baeyens, V; Buri, P; Felt, O; Gurny, R1
Chen, L; Jin, XY; Li, R; Luo, SY; Sun, XG; Wang, ZQ1
Biondi, S; Cavallaro, G; Chisari, G; Reibaldi, M1
Burgalassi, S; Di Colo, G; Nardini, I; Saettone, MF; Zambito, Y1
Boldrini, E; Campa, M; Celandroni, F; Davini, P; Ghelardi, E; Parisio, E; Salvetti, S; Senesi, S; Tavanti, A1
Bandello, F; Ferrari, E; Furlanut, M; Pavan, F; Pea, F; Roman-Pognuz, D1
Guo, H; Li, J; Liu, Z; Nie, S; Pan, W1
Blondeau, JM; Hedlin, P1
Kozai, S; Ohashi, Y; Sakaki, H; Suzuki, T; Tajika, T; Wada, T1
Bai, XQ; Deng, SJ; Li, L; Li, R; Liang, QF; Luo, SY; Sun, XG; Wang, ZQ1
Choi, JS; Joo, CK; Kim, KA; Lim, JA; Park, SH1
Abraham, S; Basavaraj, BV; Bharath, S; Deveswaran, R; Furtado, S; Madhavan, V1
Chen, H; Jiang, HR; Wu, XG; Xin, M; Yang, LN1
Ohtori, A; Tojo, K; Ueda, K1
Ohtori, A; Shikamura, Y; Tojo, K1
Chen, H; Jiang, H; Liu, T; Song, Z; Wu, X; Xu, Y; Yang, L; Yue, W1
Chen, ZJ; Han, L; Sun, ST; Wang, LY; Yue, J; Zhang, YQ1
Abdelkhalek, A; Bergstrom, BE; Hammac, GK; Seleem, MN; Townsend, WM; Younis, W1

Reviews

2 review(s) available for ofloxacin and eye

ArticleYear
[Study of intraocular diffusion of ofloxacin in humans and rabbits].
    Pathologie-biologie, 1992, Volume: 40, Issue:5

    Topics: Aged; Animals; Aqueous Humor; Cataract Extraction; Diffusion; Eye; Eye Infections, Bacterial; Humans; Injections, Intravenous; Ofloxacin; Preoperative Care; Rabbits; Staphylococcus epidermidis

1992
[Application of microdialysis for pharmacological-toxicological studies].
    The Journal of toxicological sciences, 1997, Volume: 22, Issue:3

    Topics: Animals; Eye; Humans; Intestine, Small; Kidney; Liver; Microdialysis; Muscle, Skeletal; Ofloxacin; Skin

1997

Trials

3 trial(s) available for ofloxacin and eye

ArticleYear
Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes.
    International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:5

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Eye; Female; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Tears

1997
Comparison of the ocular comfort of ofloxacin 0.3% ophthalmic solution and lubricant eye drops.
    Clinical pediatrics, 2002, Volume: 41, Issue:3

    Topics: Adult; Anti-Infective Agents; Eye; Eye Diseases; Female; Humans; Lubrication; Male; Ofloxacin; Ophthalmic Solutions; Pain; Pain Measurement

2002
Levofloxacin disposition over time in aqueous humor of patients undergoing cataract surgery.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Endophthalmitis; Eye; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Time Factors

2005

Other Studies

25 other study(ies) available for ofloxacin and eye

ArticleYear
[Intraocular penetration of DR-3355, a new quinolone derivative].
    The Japanese journal of antibiotics, 1991, Volume: 44, Issue:9

    Topics: Administration, Oral; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Eye; Ofloxacin; Rabbits

1991
The comparative in vitro activity of ofloxacin and selected ophthalmic antimicrobial agents against ocular bacterial isolates.
    American journal of ophthalmology, 1989, Oct-15, Volume: 108, Issue:4

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Physiological Phenomena; Drug Resistance, Microbial; Eye; Humans; Ofloxacin; Ophthalmic Solutions; Osmolar Concentration

1989
[Affinity of T-3761 to ocular melanin and intraocular dynamics].
    The Japanese journal of antibiotics, 1995, Volume: 48, Issue:5

    Topics: Animals; Anti-Infective Agents; Eye; Fluoroquinolones; Melanins; Ofloxacin; Oxazines; Rabbits

1995
Effect of inflammation on intraocular penetration of intravenous ofloxacin in albino rabbits.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:2

    Topics: Animals; Bacterial Infections; Endophthalmitis; Eye; Ofloxacin; Rabbits

1995
[Intraocular penetration of oral levofloxacin in rabbits].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:11

    Topics: Administration, Oral; Albinism, Ocular; Animals; Autoradiography; Eye; Levofloxacin; Melanins; Ofloxacin; Rabbits; Tissue Distribution

1994
The effect of long-term use and inflammation on the ocular penetration of topical ofloxacin.
    Current eye research, 1999, Volume: 19, Issue:6

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Aqueous Humor; Endophthalmitis; Eye; Eye Infections, Bacterial; Female; Male; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Vitreous Body

1999
Gel-forming erodible inserts for ocular controlled delivery of ofloxacin.
    International journal of pharmaceutics, 2001, Mar-14, Volume: 215, Issue:1-2

    Topics: Animals; Anti-Infective Agents; Aqueous Humor; Biological Availability; Delayed-Action Preparations; Excipients; Eye; Male; Materials Testing; Ofloxacin; Polyethylene Glycols; Rabbits; Solubility

2001
Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Jun-15, Volume: 73, Issue:2-3

    Topics: Anti-Infective Agents; Drug Delivery Systems; Drug Stability; Eye; Gels; Hydrogen-Ion Concentration; Ofloxacin; Pharmaceutical Vehicles; Solubility; Viscosity

2001
Delivery of antibiotics to the eye using a positively charged polysaccharide as vehicle.
    AAPS pharmSci, 2001, Volume: 3, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Biological Availability; Biopolymers; Chitin; Chitosan; Dosage Forms; Drug Delivery Systems; Eye; Male; Molecular Structure; Molecular Weight; Ofloxacin; Rabbits; Solubility; Solutions; Tears; Time Factors; Tobramycin; Treatment Outcome

2001
[In vitro fluoroquinolone resistance in ocular bacterial isolates].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2003, Volume: 39, Issue:3

    Topics: Actinomyces; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Eye; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Norfloxacin; Ofloxacin

2003
Presurgical antimicrobial prophylaxis: effect on ocular flora in healthy patients.
    International journal of clinical pharmacology and therapeutics, 2004, Volume: 42, Issue:1

    Topics: Administration, Topical; Adult; Antibiotic Prophylaxis; Colony Count, Microbial; Culture Media; Drug Administration Schedule; Drug Resistance, Bacterial; Eye; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Italy; Lasers, Excimer; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Ophthalmic Solutions; Photorefractive Keratectomy; Preoperative Care

2004
Effect of chitosan and of N-carboxymethylchitosan on intraocular penetration of topically applied ofloxacin.
    International journal of pharmaceutics, 2004, Apr-01, Volume: 273, Issue:1-2

    Topics: Animals; Anti-Infective Agents; Aqueous Humor; Biological Availability; Chitin; Chitosan; Eye; Instillation, Drug; Male; Ofloxacin; Ophthalmic Solutions; Permeability; Rabbits; Tears

2004
A mucoadhesive polymer extracted from tamarind seed improves the intraocular penetration and efficacy of rufloxacin in topical treatment of experimental bacterial keratitis.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9

    Topics: Adhesives; Administration, Topical; Animals; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Colony Count, Microbial; Excipients; Eye; Fluoroquinolones; Keratitis; Mucous Membrane; Ofloxacin; Plant Extracts; Pseudomonas Infections; Quinolones; Rabbits; Seeds; Staphylococcal Infections; Tamarindus

2004
Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: 1-Octanol; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cornea; Drug Carriers; Enoxacin; Ethylene Glycols; Eye; Fluoroquinolones; Gatifloxacin; In Vitro Techniques; Irritants; Levofloxacin; Ofloxacin; Oxaprozin; Permeability; Propionates; Rabbits; Ribavirin; Water

2006
Comparative minimal inhibitory and mutant prevention drug concentrations of four fluoroquinolones against ocular isolates of Haemophilus influenzae.
    Eye & contact lens, 2007, Volume: 33, Issue:3

    Topics: Anti-Infective Agents; Antimutagenic Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Eye; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Osmolar Concentration; Quinolines

2007
Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2008, Volume: 24, Issue:3

    Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Biological Availability; Disease Progression; Endophthalmitis; Enterococcus faecalis; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Male; Ofloxacin; Ointments; Ophthalmic Solutions; Quinolones; Rabbits

2008
[Analysis on susceptibility of ocular bacterial pathogens to four kinds of fluoroquinolone].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2008, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Eye; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin

2008
The resistance patterns of normal ocular bacterial flora to 4 fluoroquinolone antibiotics.
    Cornea, 2009, Volume: 28, Issue:1

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Bacteria, Aerobic; Ciprofloxacin; Conjunctiva; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2009
Sustained ophthalmic delivery of ofloxacin from an ion-activated in situ gelling system.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:2

    Topics: Administration, Topical; Alginates; Animals; Anti-Bacterial Agents; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Eye; Gels; Glucuronic Acid; Hexuronic Acids; Kinetics; Male; Ofloxacin; Ophthalmic Solutions; Rabbits; Solubility; Viscosity

2009
Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:9

    Topics: Absorption; Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Bacterial Load; Biological Availability; Cell Line; Cell Proliferation; Cornea; Disease Models, Animal; Endothelial Cells; Eye; Female; Humans; Keratitis; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Orchidaceae; Plant Extracts; Polysaccharides; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tears; Treatment Outcome

2010
Effects of pathological conditions on ocular pharmacokinetics of antimicrobial drugs.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:10

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Ciprofloxacin; Cornea; Diffusion; Eye; Ofloxacin; Rabbits; Retina; Sclera; Time Factors; Vitreous Body

2010
Drug penetration of the posterior eye tissues after topical instillation: in vivo and in silico simulation.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:10

    Topics: Administration, Topical; Animals; Anterior Eye Segment; Anti-Bacterial Agents; Aqueous Humor; Computer Simulation; Cornea; Diffusion; Eye; Ofloxacin; Rabbits; Sclera; Vitreous Body

2011
Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Animals; Anti-Infective Agents, Local; Colony Count, Microbial; Conjunctival Diseases; Cornea; Eye; Female; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Keratitis; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus

2012
[The changes of ocular bacterial isolates and in vitro antimicrobial susceptibility in the past six years].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:6

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Eye; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus epidermidis; Tobramycin

2012
Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Cations; Cell Line; Dog Diseases; Dogs; Drug Resistance, Microbial; Eye; Eye Infections, Bacterial; Gentamicins; Humans; Hydrogen Peroxide; Mice; Microbial Sensitivity Tests; Ofloxacin; Ophthalmic Solutions; Steroids; Tobramycin; Veterinary Drugs

2018