ofloxacin has been researched along with ethambutol in 111 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (2.70) | 18.7374 |
1990's | 21 (18.92) | 18.2507 |
2000's | 25 (22.52) | 29.6817 |
2010's | 55 (49.55) | 24.3611 |
2020's | 7 (6.31) | 2.80 |
Authors | Studies |
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Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Govender, K; Govender, P; Govender, T; Kruger, HG; Maguire, GE; Muthusamy, K; Onajole, OK; Pillay, M; van Helden, PD; Wiid, I | 1 |
Dempsey, S; Jack, C; Miller, CH; Nisa, S; O'Toole, R | 1 |
Banerjee, D; Bhat, P; Dinakaran, M; Gadhwal, S; Sriram, D; Yogeeswari, P | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ | 1 |
Dubey, A; Srivastava, SD; Srivastava, SK | 1 |
Bocanegra-García, V; García, A; Palma-Nicolás, JP; Rivera, G | 1 |
Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Senadeera, SP; Sureram, S | 1 |
Alexandrova, L; Andreevskaya, S; Chernousova, L; Chizhov, A; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Matyugina, E; Smirnova, T | 1 |
Alexandrova, LA; Andreevskaya, SN; Chernousova, LN; Chizhov, AO; Efremenkova, OV; Karpenko, IL; Kochetkov, SN; Shmalenyuk, ER; Smirnova, TG | 1 |
Ambady, A; Guptha, S; Hegde, N; Hosagrahara, VP; Humnabadkar, V; Kaur, P; Mahadevaswamy, J; Nagalapur, K; Narayan, A; Panda, M; Raichurkar, A; Ramachandran, S; Ramachandran, V; Rudrapatna, SS; Sambandamurthy, VK; Sharma, S; Shirude, PS | 1 |
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P | 1 |
Babu, KS; Jeankumar, VU; Reddy, KI; Renuka, J; Shravan, M; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P | 1 |
Devi, PB; Jeankumar, VU; Pedgaonkar, GS; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P | 2 |
Babu, KS; Chuppala, A; Jeankumar, VU; Reddy, KI; Renuka, J; Sree, KS; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P | 1 |
Aree, T; Ganihigama, DU; Hongmanee, P; Kittakoop, P; Mahidol, C; Ruchirawat, S; Sangher, S; Sureram, S | 1 |
Bowornwiriyapan, K; Daengrot, C; Phongpaichit, S; Rukachaisirikul, V; Sakayaroj, J; Tansakul, C; Thongpanchang, T | 1 |
Renuka, J; Samala, G; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P | 1 |
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bowornwiriyapan, K; Duangjai, A; Muanprasat, C; Phainuphong, P; Phongpaichit, S; Rukachaisirikul, V; Saithong, S; Sakayaroj, J; Srimaroeng, C | 1 |
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K | 1 |
Avalos-Alanís, FG; Carranza-Rosales, P; Guzmán-Delgado, NE; Hernández-Fernández, E; Hernández-Fernández, J; López-Cortina, S; Morales-Vargas, A; Ordóñez, M; Santiago-Mauricio, MG; Velázquez-Moreno, VM | 1 |
Mahajan, SS; Saharan, VD | 1 |
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H | 1 |
Alluri, KK; Gottapu, S; Reshma, RS; Sriram, D; Suraparaju, R | 1 |
Bishai, WR; Duan, G; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
Bera, S; Mondal, D | 1 |
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K | 1 |
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR | 1 |
Hara, K; Kaku, M; Koga, H; Kohno, S; Maesaki, S | 1 |
Tsukamura, M; Yamori, S | 1 |
Hoffner, SE; Källenius, G; Kratz, M; Olsson-Liljequist, B; Svenson, SB | 1 |
Saito, H; Tsukamura, M; Yasuda, Y; Yoshii, S | 1 |
Berning, SE; Elliott, AM; Iseman, MD; Peloquin, CA | 1 |
Bagnato, GF; Cucinotta, D; Di Cesare, E; Gulli, S | 1 |
Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H | 1 |
Graybill, JR; Moreno, F; Valero, G | 1 |
Bryskier, A; Goh, KS; Rastogi, N | 1 |
Nicolau, DP; Nightingale, CH; Onyeji, CO; Quintiliani, R | 1 |
Bermudez, LE; Kolonoski, P; Young, LS | 1 |
Barbara-Burnham, L; Bermudez, LE; Inderlied, CB; Kolonoski, P; Wu, M; Young, LS | 1 |
Braun, TW; Hilton, E; Ruggiero, SL | 1 |
Bryskier, A; Devallois, A; Goh, KS; Rastogi, N | 1 |
Furukawa, T; Komachi, H; Nagai, R; Saito, Y; Takewaki, S; Uchihara, T | 1 |
Tanaka, E | 1 |
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE | 1 |
Collins, LA; Franzblau, SG; Torrero, MN | 1 |
Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE | 1 |
Fridolijn Jongevos, S; Habets, JM; Prens, EP | 1 |
Duan, L; Li, H; Liang, G | 1 |
de Jong, JJ; Endtz, HP; IJzermans, JN; van Gelder, T; Weimar, W | 1 |
Emre, S; Meyers, BR; Miller, C; Papanicolaou, GA; Sheiner, P | 1 |
Bajaksouzian, S; Jacobs, MR; Joloba, ML | 1 |
Cheon, SH; Dietze, R; Ellner, JJ; Hise, AG; Landen, K; Palaci, M; Phillips, M; Ribeiro, FC; Song, HY; Vinhas, S; Wallis, RS | 1 |
Bowersox, J | 1 |
Amthor, M; Burkhardt, U; Ernst, M; Richter, E; Rosahl, W; Rüsch-Gerdes, S; Schreiber, J; Zugehör, M | 1 |
Brade, V; Enzensberger, R; Gruschke, A | 1 |
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA | 1 |
Dailloux, M; Dauendorffer, JN; Laurain, C; Weber, M | 1 |
Janulionis, E; Sofer, C; Song, HY; Wallis, RS | 1 |
Hoeppner, VH; Jones, W; Marciniuk, DD; Ward, HA | 1 |
Avramopoulos, I; Falagas, ME; Rafailidis, PI; Sapkas, G | 1 |
Bhusal, Y; Shiohira, CM; Yamane, N | 1 |
Baum, GL; Daniele, B; Kramer, MR; Lavy, A; Priess, R; Raz, M; Shitrit, AB; Shitrit, D; Shlomi, D | 1 |
Conde, MB; Dorman, SE; Guerra, RL; Mello, FC; Muzy-de-Souza, GR; Szklo, A | 1 |
Otomo, K; Shi, R; Sugawara, I; Zhang, G; Zhang, J | 1 |
Chen, HW; Lai, CC; Tan, CK | 1 |
Martínez, E; Nam-Cha, S; Puerta, A; Salinas, A | 1 |
Chen, YC; Ho, CC; Hu, FC; Luh, KT; Yang, PC; Yu, CJ | 1 |
Agarwal, A; Arora, A; Kumar, S | 1 |
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A | 1 |
Hagiwara, E; Komatsu, S; Ogura, T; Sawahata, M; Sekine, A; Takahashi, H; Tsuchiya, N | 1 |
Campbell, PJ; Cowan, LS; Dalton, TL; Hooks, DP; Metchock, B; Morlock, GP; Plikaytis, BB; Posey, JE; Sikes, RD; Starks, AM | 1 |
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA | 1 |
Desai, VB; Fredrick, JS; Joseph, P; Mohan, NS; Ramachandran, R; Raman, B; Thomas, A; Wares, F | 1 |
Connolly, C; Friedland, G; Gandhi, N; Moodley, P; Shah, NS; Sturm, AW; Tayob, N; Zetola, N | 1 |
Hsueh, PR; Huang, YT; Lai, CC; Liao, CH; Tan, CK | 1 |
Baba, K; Ehlers, MM; Hoosen, AA; Ismail, NA; Kock, MM; Omar, SV; Osman, AG; Said, HM | 1 |
González-Martín, J; Martínez, JA; Rey-Jurado, E; Tudó, G | 1 |
Hassan, G; Kant, S; Parengal, J; Saheer, S | 1 |
Barnard, M; Bosman, M; Coetzee, G; Gey Van Pittius, N; O'Brien, R; Streicher, E; van Helden, P; Warren, R | 1 |
Diao, N; Fan, X; Jin, J; Shen, Y; Wang, F; Wang, S; Weng, X; Zhang, W | 1 |
Lu, J; Pang, Y; Song, Y; Wang, S; Wang, Y; Zhao, Y | 1 |
Choe, KH; Chung, GT; Hwang, SC; Jnawali, HN; Kim, H; Lee, YS; Park, YK; Ryoo, S | 1 |
Aboud, C; Algood, H; Boyd, AS; Braun, N; Burke, VE; Drake, WP; Isom, J; Kaminski, N; King, LE; Oswald-Richter, K; Pandit, KV; Richmond, BW; Taylor, T; Yu, C | 1 |
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A | 1 |
Cox, H; Fielding, K; Finlayson, H; Godfrey-Faussett, P; Hesseling, AC; Hughes, J; Schaaf, HS; Seddon, JA | 1 |
Liu, B; Pang, Y; Wang, Y; Zhang, D | 1 |
Chen, ST; Huang, HR; Jiang, GL; Ma, YF; Wang, GR; Yu, X | 1 |
Abbas, M; Ehtisham-Ul-Haque, S; Javed, I; Javed, MT; Mahmood, Z; Riaz, M; Shahid, M | 1 |
Hosmane, GB; Jain, A; Kushwaha, RA; Prasad, R; Singh, A; Srivastava, R | 1 |
Ahmad, N; Javaid, A; Khan, AH; Shaheen, Z | 1 |
Chen, YH; Huang, CH; Kuo, CY; Lu, PL; Wang, WH | 1 |
Anupurba, S; Balgam, S; Fakir, NA; Gupta, A; Nema, V; Pal, SK; Pandey, D; Periera, M; Rathod, S; Sekar, G; Sinha, D; Sinha, P; SivaKumar, S; UmaDevi, KR | 1 |
Clifton, DA; Crook, DW; Iqbal, Z; Niehaus, KE; Peto, TEA; Smith, EG; Walker, AS; Walker, TM; Wilson, DJ; Yang, Y; Zhu, T | 1 |
Antiabong, JF; Lekalakala, RM; Malinga, LA; Maningi, NE; Mbelle, NM | 1 |
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM | 1 |
Gao, R; Guo, Y; Shen, X; Tan, G; Wang, H; Wu, X; Wu, Z; Yang, J; Yu, F | 1 |
Jafari, R; Moghim, S; Nasr Esfahani, B; Safari, M; Salehi, M | 1 |
Ahmed, S; Banu, S; Khatun, R; Nasrin, R; Rahman, A; Rahman, MM; Rahman, SMM; Uddin, MKM | 1 |
Guo, Y; Liu, H; Sha, W; Shen, H; Shen, X; Tan, G; Wu, X; Wu, Z; Yang, J; Yu, F | 1 |
Guo, Y; Huang, C; Sha, W; Tan, G; Wu, X; Yang, J; Yu, F | 1 |
Adhikary, A; Biswal, S; Chatterjee, D; Ghosh, AS | 1 |
6 review(s) available for ofloxacin and ethambutol
Article | Year |
---|---|
Recent advances in antitubercular natural products.
Topics: Animals; Antitubercular Agents; Biological Products; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Mycobacterium tuberculosis; Tuberculosis | 2012 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis | 2021 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
[Pulmonary mycobacteriosis caused by Mycobacterium peregrinum in a young, healthy man].
Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2010 |
7 trial(s) available for ofloxacin and ethambutol
Article | Year |
---|---|
Prospective comparative study of ofloxacin or ethambutol for the treatment of pulmonary tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Combinations; Drug Resistance, Microbial; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Prospective Studies; Rifampin; Time Factors; Tuberculosis, Pulmonary | 1992 |
[Pilot studies on the treatment of Mycobacterium avium complex lung disease--new macrolides and new quinolones. (2) Multi-drug chemotherapy for initial cases on trial].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Humans; Kanamycin; Mycobacterium avium-intracellulare Infection; Ofloxacin; Pilot Projects; Rifampin; Tuberculosis, Pulmonary | 1996 |
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis | 1997 |
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 1998 |
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult | 2011 |
Outcome of standardized treatment for patients with MDR-TB from Tamil Nadu, India.
Topics: Adult; Antibiotics, Antitubercular; Communicable Disease Control; Cycloserine; Directly Observed Therapy; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Ethionamide; Female; Humans; India; Kanamycin; Male; Middle Aged; Ofloxacin; Prospective Studies; Pyrazinamide; Sputum; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2011 |
Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Azithromycin; CD4-Positive T-Lymphocytes; Chronic Disease; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Rifampin; Sarcoidosis; Severity of Illness Index; Single-Blind Method; Skin Diseases; Transcriptome; Treatment Outcome; Young Adult | 2013 |
98 other study(ies) available for ofloxacin and ethambutol
Article | Year |
---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Pentacyclo-undecane derived cyclic tetra-amines: synthesis and evaluation as potent anti-tuberculosis agents.
Topics: Alkanes; Animals; Antitubercular Agents; Cattle; Cell Line; Cell Survival; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Prenylation | 2009 |
Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Topics: Antitubercular Agents; Cysteine; Drug Evaluation, Preclinical; Mycobacterium; Mycobacterium smegmatis; Organoselenium Compounds; Selenocysteine; Small Molecule Libraries | 2009 |
Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno[3,2-c]pyridin-3-yl derivatives.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Microbial Sensitivity Tests; Pyridines; Vero Cells | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin | 2010 |
Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: a new class of biological compounds.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Azetidines; Microbial Sensitivity Tests; Microwaves; Mycobacterium tuberculosis; Triazoles | 2011 |
Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis.
Topics: Alkaloids; Antitubercular Agents; Benzylisoquinolines; Drug Resistance, Multiple, Bacterial; Humans; Magnetic Resonance Spectroscopy; Menispermaceae; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Plant Extracts; Plant Roots; Tuberculosis, Multidrug-Resistant | 2012 |
The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism; Uracil; Vero Cells | 2012 |
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Humans; Jurkat Cells; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidine Nucleosides; Structure-Activity Relationship; Vero Cells | 2013 |
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Oxidoreductases; Pyrazoles; Pyridones; Structure-Activity Relationship | 2014 |
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2014 |
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Benzofurans; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Drug Design; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2014 |
Development of 2-(4-oxoquinazolin-3(4H)-yl)acetamide derivatives as novel enoyl-acyl carrier protein reductase (InhA) inhibitors for the treatment of tuberculosis.
Topics: Acetamides; Animals; Bacterial Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Oxidoreductases; Quinazolines; Structure-Activity Relationship; Tuberculosis | 2014 |
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Cell Line; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Structure-Activity Relationship; Tuberculosis | 2014 |
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.
Topics: Animals; Antitubercular Agents; Benzofurans; Benzothiazoles; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2014 |
Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Biological Products; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Quinolines; Structure-Activity Relationship | 2015 |
Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138.
Topics: Animals; Antimalarials; Antineoplastic Agents; Biphenyl Compounds; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Penicillium; Plasmodium falciparum; Sesquiterpenes; Soil Microbiology; Sulfides; Thailand; Vero Cells | 2015 |
Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.
Topics: Antitubercular Agents; DNA Gyrase; Drug Discovery; Humans; Mycobacterium smegmatis; Mycobacterium tuberculosis | 2015 |
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles | 2016 |
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.
Topics: Animals; Aspergillus; Chlorocebus aethiops; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; KB Cells; Lovastatin; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium scrofulaceum; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Soil Microbiology; Thailand; Vero Cells | 2016 |
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles | 2017 |
Synthesis, antimycobacterial and cytotoxic activity of α,β-unsaturated amides and 2,4-disubstituted oxazoline derivatives.
Topics: Amides; Animals; Antitubercular Agents; Liver; Microbial Sensitivity Tests; Microscopy; Mycobacterium tuberculosis; Oxazoles; Rats; Structure-Activity Relationship | 2017 |
Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Formazans; Gallic Acid; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; RAW 264.7 Cells; Tuberculosis | 2017 |
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water | 2017 |
Synthesis and evaluation of 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] analogues against both active and dormant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrans; Spiro Compounds; Structure-Activity Relationship; Thiophenes | 2018 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Polyketide Synthases; Structure-Activity Relationship; Vero Cells | 2019 |
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2019 |
[Chemotherapeutic regimens for nontuberculous mycobacterial infection based on in-vitro susceptibility test results].
Topics: Drug Resistance, Microbial; Drug Therapy, Combination; Enviomycin; Ethambutol; Humans; Isoniazid; Mycobacterium; Mycobacterium Infections; Ofloxacin; Rifampin; Viomycin | 1990 |
[Rifabutine in the treatment of mycobacterial infections resistant to rifampicin. Preliminary results. Group for the Study and Treatment of Resistant Mycobacterial Infections (GETIM)].
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Ofloxacin; Rifabutin; Rifampin; Rifamycins; Tuberculosis, Pulmonary | 1989 |
In-vitro synergistic activity between ethambutol and fluorinated quinolones against Mycobacterium avium complex.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Norfloxacin; Ofloxacin | 1989 |
[Antituberculosis chemotherapy including ofloxacin in patients with pulmonary tuberculosis not treated previously].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Ofloxacin; Oxazines; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1986 |
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema.
Topics: Aged; Antitubercular Agents; Chronic Disease; Empyema, Tuberculous; Ethambutol; Humans; Male; Ofloxacin; Pleural Effusion; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 1995 |
Long-term treatment of pulmonary tuberculosis with ofloxacin in a subject with liver cirrhosis.
Topics: Administration, Oral; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Follow-Up Studies; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Ofloxacin; Tuberculosis, Pulmonary; Uric Acid | 1995 |
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin | 1995 |
Activities of clarithromycin, ofloxacin, and clarithromycin plus ethambutol against Mycobacterium simiae in murine model of disseminated infection.
Topics: Animals; Clarithromycin; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Skin Diseases, Bacterial; Splenic Diseases | 1994 |
Activities of roxithromycin used alone and in combination with ethambutol, rifampin, amikacin, ofloxacin, and clofazimine against Mycobacterium avium complex.
Topics: Amikacin; Clofazimine; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Ofloxacin; Rifampin; Roxithromycin | 1994 |
Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages.
Topics: Clarithromycin; Colony Count, Microbial; Drug Carriers; Ethambutol; Humans; In Vitro Techniques; Liposomes; Macrophages; Mycobacterium avium Complex; Ofloxacin | 1994 |
Roxithromycin alone and in combination with either ethambutol or levofloxacin for disseminated Mycobacterium avium infections in beige mice.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacteremia; Colony Count, Microbial; Drug Combinations; Ethambutol; Levofloxacin; Mice; Mycobacterium avium; Ofloxacin; Roxithromycin; Spleen; Tuberculosis | 1996 |
Activities of bay Y 3118, levofloxacin, and ofloxacin alone or in combination with ethambutol against Mycobacterium avium complex in vitro, in human macrophages, and in beige mice.
Topics: Animals; Anti-Infective Agents; Cell Line; Drug Combinations; Ethambutol; Female; Fluoroquinolones; Humans; Levofloxacin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rats | 1996 |
Trismus and preauricular swelling in a 20-year-old black woman.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Capreomycin; Diagnosis, Differential; Edema; Ethambutol; Female; Haiti; Humans; Ofloxacin; Temporomandibular Joint Disorders; Trismus; Tuberculosis, Multidrug-Resistant; Tuberculosis, Oral; Tuberculosis, Osteoarticular | 1996 |
Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clofazimine; Drug Combinations; Ethambutol; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Ofloxacin; Rifampin; Roxithromycin | 1996 |
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Cycloserine; Ethambutol; Humans; Injections, Spinal; Isoniazid; Male; Meningitis; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Ofloxacin; Polymerase Chain Reaction; Rifampin; Streptomycin | 1996 |
Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Cell Division; Drug Evaluation, Preclinical; Electroporation; Ethambutol; Green Fluorescent Proteins; Indicators and Reagents; Isoniazid; Luminescent Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Transformation, Bacterial | 1998 |
Successful triple-antibiotic therapy for cutaneous infection due to Mycobacterium chelonae.
Topics: Aged; Doxycycline; Drug Therapy, Combination; Ethambutol; Female; Humans; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Ofloxacin; Skin; Skin Diseases, Bacterial | 1999 |
[Experimental study on the antituberculous activity of ofloxacins].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Female; Male; Mice; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis | 1997 |
Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient.
Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Foot; Humans; Kidney Transplantation; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Postoperative Complications; Rifampin; Skin Diseases, Bacterial | 1999 |
Tuberculosis in orthotopic liver transplant patients: increased toxicity of recommended agents; cure of disseminated infection with nonconventional regimens.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Ethambutol; Female; Humans; Liver; Liver Transplantation; Male; Middle Aged; Ofloxacin; Postoperative Complications; Retreatment; Treatment Outcome; Tuberculosis | 2000 |
Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis.
Topics: Agar; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin | 2000 |
A whole blood bactericidal assay for tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin | 2001 |
CPCRA researchers present OI studies at Vancouver.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis | 1996 |
[Non-tubercular mycobacterial infection of the lungs due to Mycobacterium smegmatis].
Topics: Cardiopulmonary Resuscitation; CD4-Positive T-Lymphocytes; Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Lung Diseases; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Ofloxacin; Radiography; Rifabutin | 2001 |
[Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS].
Topics: Abscess; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Immunocompromised Host; Levofloxacin; Male; Middle Aged; Mycobacterium haemophilum; Mycobacterium Infections; Ofloxacin; Osteomyelitis; Recurrence; Rifabutin; Tibia | 2002 |
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci).
Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis | 2002 |
In vitro sensitivity of Mycobacterium xenopi to five antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Clarithromycin; Ethambutol; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium xenopi; Ofloxacin; Rifampin | 2002 |
Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture.
Topics: Anti-Infective Agents; Antitubercular Agents; Area Under Curve; Blood; Cells, Cultured; Clofazimine; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Serum Bactericidal Test | 2004 |
Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.
Topics: Capreomycin; Cycloserine; Drug Therapy, Combination; Emigration and Immigration; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Male; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam | 2005 |
Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates.
Topics: Anti-Bacterial Agents; Biopsy, Fine-Needle; Bone Transplantation; Cycloserine; Discitis; Drug Therapy, Combination; Ethambutol; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Thoracic Vertebrae; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Osteoarticular; Vitamin B 6; Vitamin B Complex | 2006 |
Determination of in vitro synergy when three antimicrobial agents are combined against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Drug Synergism; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2005 |
Pulmonary Mycobacterium kansasii infection in Israel, 1999-2004: clinical features, drug susceptibility, and outcome.
Topics: Adult; Antibiotics, Antitubercular; Ciprofloxacin; Clarithromycin; Cycloserine; Ethambutol; Ethionamide; Female; Humans; Israel; Lung Diseases; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Ofloxacin; Prognosis; Rifampin | 2006 |
Alternative anti-tuberculosis regimen including ofloxacin for the treatment of patients with hepatic injury.
Topics: Antitubercular Agents; Brazil; Cohort Studies; Comorbidity; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Hospitals, Public; Humans; Liver Diseases; Liver Function Tests; Male; Mycobacterium tuberculosis; Odds Ratio; Ofloxacin; Recurrence; Retrospective Studies; Risk Assessment; Severity of Illness Index; Streptomycin; Survival Rate; Treatment Failure; Treatment Outcome; Tuberculosis, Pulmonary; Urban Population | 2007 |
Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.
Topics: Antitubercular Agents; Bacterial Proteins; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Tuberculosis | 2007 |
Arthritis caused by Mycobacterium terrae in a patient with rheumatoid arthritis.
Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Azithromycin; Drug Therapy, Combination; Ethambutol; Humans; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Ofloxacin; Treatment Outcome | 2009 |
[Renal mass in an HIV-positive elderly patient].
Topics: Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Nephrectomy; Ofloxacin; Pyrazinamide; Tomography, X-Ray Computed; Tuberculosis, Renal | 2009 |
Safety of fluoroquinolone use in patients with hepatotoxicity induced by anti-tuberculosis regimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Bacterial Agents; Antitubercular Agents; Aspartate Aminotransferases; Aza Compounds; Ethambutol; Female; Fluoroquinolones; Hepatic Insufficiency; Humans; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Streptomycin; Treatment Outcome; Tuberculosis; Young Adult | 2009 |
A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective.
Topics: Antitubercular Agents; Congresses as Topic; Ethambutol; Humans; Infectious Disease Medicine; Isoniazid; Ofloxacin; Orthopedics; Practice Patterns, Physicians'; Pyrazinamide; Rifampin; Streptomycin; Surveys and Questionnaires; Tuberculosis, Osteoarticular | 2009 |
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2011 |
Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa.
Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Ofloxacin; Rifampin; South Africa; Streptomycin | 2011 |
Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.
Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Female; Fluoroquinolones; Humans; Isoniazid; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifabutin; Rifampin; Streptomycin; Taiwan; Tuberculosis, Multidrug-Resistant | 2011 |
Evaluation of the GenoType® MTBDRsl assay for susceptibility testing of second-line anti-tuberculosis drugs.
Topics: Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Ethambutol; Genotype; Humans; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Phenotype; Polymerase Chain Reaction; Predictive Value of Tests; RNA, Bacterial; RNA, Ribosomal, 16S; Sensitivity and Specificity; Tuberculosis, Multidrug-Resistant | 2012 |
Synergistic effect of two combinations of antituberculous drugs against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin | 2012 |
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant | 2012 |
Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory.
Topics: Amikacin; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Genetic Markers; Genotype; Humans; Microbial Sensitivity Tests; Molecular Diagnostic Techniques; Mycobacterium tuberculosis; Ofloxacin; Pentosyltransferases; Rifampin; Sensitivity and Specificity; South Africa; Sputum; Time Factors | 2012 |
Underestimation of the resistance of Mycobacterium tuberculosis to second-line drugs by the new GenoType MTBDRsl test.
Topics: Antitubercular Agents; China; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity; Sequence Analysis, DNA | 2013 |
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Biological Transport; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Escherichia coli; Ethambutol; Genotype; Isoniazid; Kanamycin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Protein Structure, Secondary; Protein Structure, Tertiary; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis | 2013 |
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2013 |
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India.
Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis | 2013 |
Preventive therapy for child contacts of multidrug-resistant tuberculosis: a prospective cohort study.
Topics: Antitubercular Agents; Child, Preschool; Ethambutol; Female; HIV Infections; Humans; Infant; Infant, Newborn; Isoniazid; Male; Ofloxacin; Prospective Studies; Risk Factors; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2013 |
Rapid molecular screening for multidrug-resistant tuberculosis in a resource-limited region of China.
Topics: Antitubercular Agents; Bacterial Proteins; China; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genes, Bacterial; Humans; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2014 |
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2016 |
Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Streptomycin | 2016 |
Frequency of adverse events observed with second-line drugs among patients treated for multidrug-resistant tuberculosis.
Topics: Adult; Antitubercular Agents; Cohort Studies; Cycloserine; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Humans; Kanamycin; Male; Ofloxacin; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Young Adult | 2016 |
Applicability of the World Health Organization recommended new shorter regimen in a multidrug-resistant tuberculosis high burden country.
Topics: Adult; Antitubercular Agents; Communicable Disease Control; Drug Administration Schedule; Ethambutol; Female; Humans; Infectious Disease Medicine; Male; Mycobacterium tuberculosis; Ofloxacin; Pakistan; Pyrazinamide; Streptomycin; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult | 2017 |
Resistance to first- and second-line antituberculosis drugs in Southern Taiwan: Implications for empirical treatment.
Topics: Aminosalicylic Acid; Antitubercular Agents; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Streptomycin; Taiwan | 2018 |
PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.
Topics: Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Genetic Variation; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mitoxantrone; Molecular Docking Simulation; Mutation; Mycobacterium tuberculosis; Ofloxacin; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rifampin; Sequence Analysis; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
Machine learning for classifying tuberculosis drug-resistance from DNA sequencing data.
Topics: Antitubercular Agents; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Machine Learning; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2018 |
Comparison of line probe assay to BACTEC MGIT 960 system for susceptibility testing of first and second-line anti-tuberculosis drugs in a referral laboratory in South Africa.
Topics: Antitubercular Agents; DNA, Bacterial; Ethambutol; Female; Genotype; Humans; Isoniazid; Kanamycin; Laboratories; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Referral and Consultation; Rifampin; South Africa | 2017 |
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling.
Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant | 2018 |
Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
Topics: Adult; Amikacin; Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Male; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis; Whole Genome Sequencing | 2020 |
Sequence-based detection of first-line and second-line drugs resistance-associated mutations in Mycobacterium tuberculosis isolates in Isfahan, Iran.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Capreomycin; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Genetic Variation; Genotype; Humans; Iran; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2020 |
Performance of GenoType MTBDRsl assay for detection of second-line drugs and ethambutol resistance directly from sputum specimens of MDR-TB patients in Bangladesh.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bangladesh; DNA, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Genotyping Techniques; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Sensitivity and Specificity; Sputum; Tuberculosis, Multidrug-Resistant | 2021 |
Use of Whole-Genome Sequencing to Predict
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2022 |
Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
Topics: Amikacin; Antitubercular Agents; China; Drug Resistance; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nucleotides; Ofloxacin; Rifampin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomycin; Tuberculosis, Lymph Node | 2022 |
A NiCoT family metal transporter of
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cobalt; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Ethambutol; Gentamicins; Isoleucine; Isoniazid; Kanamycin; Leucine; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nalidixic Acid; Neomycin; Nickel; Norfloxacin; Ofloxacin | 2022 |