ofloxacin and dapsone

ofloxacin has been researched along with dapsone in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.67)18.7374
1990's10 (22.22)18.2507
2000's8 (17.78)29.6817
2010's20 (44.44)24.3611
2020's4 (8.89)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bera, S; Mondal, D1
Banerjee, DK; McDermott-Lancaster, RD1
Jidoi, J; Saito, H; Tomioka, H; Yamada, Y1
Beoletto, C; Grosset, JH; Guelpa-Lauras, CC; Perani, EG1
Grosset, JH1
Grosset, JH; Ji, B; N'Deli, L; Perani, EG; Petinom, C1
Ramachandran, A; Rao, PS; Ravi, S; Sekar, B; Subramanian, M1
Cambau, E; Guillemin, I; Jamet, P; Ji, B; Perani, E1
Grosset, JH; Jamet, P; Ji, B; Perani, EG; Sow, S; Traore, I1
Maw, WW; Saito, H; Sato, K; Tomioka, H1
Bhattacharya, SN; Jain, S; Kumar, S; Sehgal, VN1
Arra, GS; Arutla, S; Krishna, DR; Prabhakar, CM1
Chauhan, DS; Gupta, UD; Katoch, K; Katoch, VM; Natrajan, M; Sharma, RK; Sharma, VD; Singh, D; Singh, HB; Srivastava, K1
Kashiwabara, Y; Matsuoka, M; Namisato, M1
Abalos, RM; Balagon, MV; Cellona, RV; Dela Cruz, EC; Fajardo, TT; Tan, EV; Villahermosa, LG; Walsh, DS; Walsh, GP1
Maeda, S1
Biswas, SK1
Matsuoka, M; Suzuki, Y1
Arenas, R; Asz-Sigall, D; López-García, L; Neme-Yunes, Y; Vega-Memije, ME; Yuen-Palos, R1
Abalos, RM; Balagon, MF; Cellona, RV; Gelber, RH; Saunderson, PR1
Hall, JM; Kahn, MA; Moreland, AA; Moschella, SL; Torske, KR1
Carreño-Martinez, C; Fafutis-Morris, M; Fukushima, Y; Garcia, IE; Matsuoka, M; Nakajima, C; Suzuki, Y; Vargas-González, A1
Arunagiri, K; Kumar, BN; Menaka, K; Narayanan, S; Oommen, PK; Sekar, B1
Andries, K; Bantubani, N; De Marez, T; Diacon, AH; Donald, PR; Grobusch, M; Lounis, N; Mahanyele, R; McNeeley, DF; Meyvisch, P; Narasimooloo, R; Patientia, RF; Pym, A; van Heeswijk, R1
Cunha, Mda G; Lockwood, DN1
Avelleira, JC; Campos, AA; Cruz, RC; Cunha, Mda G; Filho, B; Ghuidella, C; Schettini, AP; Ura, S; Viana, Fdos R; Virmond, M1
Colorado, CL; Guerrero, MI; León, CI; Torres, JF1
Chen, M; Fu, X; Liu, D; Liu, H; Sun, Y; Wang, C; Wang, J; Yu, X; Zhang, F; Zhang, Q; Zhang, Y; Zhou, G1
Beltrán-Alzate, C; Brennan, P; Cardona-Castro, N; Kimura, M; Li, W; López Díaz, F; Romero-Montoya, M; Sakamuri, R1
Araujo, S; Fontes, AB; Goulart, IMB; Goulart, LR; Li, W; Matsuoka, M; Rosa, PS; Scollard, DM; Suffys, P; Truman, RW; Vissa, V; Williams, DL1
Boggild, AK; Bonnar, PE; Cunningham, NP; Davis, IRC; Sharma, R; Walsh, NM1
Cambau, E; Cardona-Castro, N; Cauchoix, B; Cole, ST; Cooreman, EAWD; Gillini, L; Gupta, UD; Hagge, D; Hongseng, W; Indropo, A; Johnson, RC; Kai, M; Lavania, M; Matsuoka, M; Miyamoto, Y; Pannikar, VK; Pemmaraju, VRR; Rosa, PS; Saunderson, P; Srikantam, A; Suffys, P; Vissa, V; Williams, D1
Ahuja, M; Darlong, J; Hembrom, S; Lavania, M; Pathak, VK; Sengupta, U; Singh, I; Singh, SV; Turankar, RP1
Jin, G; Li, G; Li, X; Li, Y; Shao, Y; Wei, P; Yang, J; Zhang, L1
Ahuja, M; Khurana, A; Muddebihal, A; Sachdeva, S; Sardana, K; Sharma, R; Singh, I1
Chhabra, S; Dogra, S; Jain, S; Kaur, M; Minz, RW; Nadeem, M; Narang, T; Pandey, P; Sahu, S; Sharma, A; Sharma, K; Sharma, R; Shilpa, S; Singh, I; Yadav, R1

Reviews

5 review(s) available for ofloxacin and dapsone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Pharmacokinetics in drug screening.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1987, Volume: 55, Issue:4 Suppl

    Topics: Animals; Biological Availability; Body Weight; Dapsone; Drug Evaluation, Preclinical; Humans; Leprostatic Agents; Leprosy; Ofloxacin; Oxazines; Rifampin; Species Specificity

1987
[DNA microarray based rapid drug susceptibility test for Mycobacterium leprae].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2006, Volume: 75, Issue:3

    Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mice; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae; Ofloxacin; Oligonucleotide Array Sequence Analysis; Rifampin

2006
Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis.
    International journal of molecular sciences, 2022, Oct-18, Volume: 23, Issue:20

    Topics: Amino Acids; Dapsone; Drug Resistance, Bacterial; Humans; Leprostatic Agents; Leprosy; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae; Ofloxacin; Rifampin

2022

Trials

7 trial(s) available for ofloxacin and dapsone

ArticleYear
Clinical trial of ofloxacin alone and in combination with dapsone plus clofazimine for treatment of lepromatous leprosy.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Foot; Humans; Leprosy, Lepromatous; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Mycobacterium leprae; Ofloxacin; Skin

1994
Ofloxacin-containing combined drug regimens in the treatment of lepromatous leprosy.
    Leprosy review, 1994, Volume: 65, Issue:3

    Topics: Adult; Animals; Anti-Infective Agents; Biopsy, Needle; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Leprosy, Lepromatous; Male; Mice; Ofloxacin; Treatment Outcome

1994
High relapse rate among lepromatous leprosy patients treated with rifampin plus ofloxacin daily for 4 weeks.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:9

    Topics: Adult; Anti-Infective Agents; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy, Lepromatous; Male; Middle Aged; Ofloxacin; Recurrence; Rifampin

1997
Parallel assessment of 24 monthly doses of rifampin, ofloxacin, and minocycline versus two years of World Health Organization multi-drug therapy for multi-bacillary leprosy.
    The American journal of tropical medicine and hygiene, 2004, Volume: 70, Issue:2

    Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Leprosy; Male; Middle Aged; Minocycline; Ofloxacin; Rifampin

2004
The efficacy of a four-week, ofloxacin-containing regimen compared with standard WHO-MDT in PB leprosy.
    Leprosy review, 2010, Volume: 81, Issue:1

    Topics: Adult; Dapsone; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy, Paucibacillary; Male; Middle Aged; Ofloxacin; Recurrence; Rifampin; Skin; Time Factors; Treatment Outcome; World Health Organization

2010
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Antitubercular Agents; Clarithromycin; Cycloserine; Dapsone; Diarylquinolines; Erythromycin; Female; Humans; Isoxazoles; Male; Ofloxacin; Oxazolidinones; Quinolines; Tuberculosis, Multidrug-Resistant

2012
OFLOXACIN multicentre trial in MB leprosy FUAM-Manaus and ILSL-Bauru, Brazil.
    Leprosy review, 2012, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Animals; Brazil; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy, Multibacillary; Male; Mice; Middle Aged; Mycobacterium leprae; Ofloxacin; Prevalence; Rifampin; Secondary Prevention; Skin; Time Factors; Treatment Outcome; World Health Organization; Young Adult

2012

Other Studies

33 other study(ies) available for ofloxacin and dapsone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
An experimental study to evaluate the bactericidal activity of ofloxacin against an established Mycobacterium leprae infection.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:3

    Topics: Animals; Dapsone; Disease Models, Animal; Drug Therapy, Combination; Leprosy; Mice; Mice, Nude; Mycobacterium leprae; Ofloxacin; Rifampin; Serum Bactericidal Test

1992
Susceptibilities of Mycobacterium leprae and M. avium complex to the H2O2-Fe-mediated halogenation system supplemented with antimicrobial agents.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1989, Volume: 57, Issue:3

    Topics: Animals; Clofazimine; Dapsone; Ethidium; Ferrous Compounds; Fluoresceins; Humans; Hydrogen Peroxide; Iodides; Mice; Mycobacterium avium Complex; Mycobacterium leprae; Ofloxacin; Rifampin; Sodium Iodide; Staining and Labeling

1989
Activity of ofloxacin against Mycobacterium leprae in the mouse.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1988, Volume: 56, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Dapsone; Female; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Prothionamide

1988
Multidrug-resistance to dapsone, rifampicin, and ofloxacin in Mycobacterium leprae.
    Lancet (London, England), 1997, Jan-11, Volume: 349, Issue:9045

    Topics: Adult; Anti-Infective Agents; Dapsone; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy, Lepromatous; Male; Mycobacterium leprae; Ofloxacin; Rifampin

1997
Studies on therapeutic activity of benzoxazinorifamycin KRM-1648 in combination with other antimicrobial agents and biological response modifiers interferon-gamma and granulocyte-macrophage colony-stimulating factor against M. leprae infection in athymic
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1997, Volume: 65, Issue:3

    Topics: Adoptive Transfer; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunologic Factors; Interferon-gamma; Leprostatic Agents; Leprosy; Mice; Mice, Inbred BALB C; Mice, Nude; Ofloxacin; Rifamycins

1997
Relapse (reactivation) in borderline tuberculoid (BT) leprosy.
    The Journal of dermatology, 1998, Volume: 25, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Monitoring; Granuloma; Histiocytes; Humans; Leprostatic Agents; Leprosy, Borderline; Leprosy, Tuberculoid; Lymphocytes; Male; Minocycline; Ofloxacin; Recurrence; Rifampin

1998
[New WHO recommendations for the treatment of leprosy].
    Acta leprologica, 1997, Volume: 10, Issue:4

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Minocycline; Mycobacterium leprae; Ofloxacin; Rifampin; Skin

1997
Pro- and anti-oxidant effects of some antileprotic drugs in vitro and their influence on super oxide dismutase activity.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:10

    Topics: Antioxidants; Clofazimine; Dapsone; Dianisidine; Leprostatic Agents; Ofloxacin; Reactive Oxygen Species; Riboflavin; Rifampin; Superoxide Dismutase; Superoxides

1998
Effect of treatment on PCR positivity in multibacillary leprosy patients treated with conventional and newer drugs ofloxacin and minocycline.
    Acta leprologica, 1999, Volume: 11, Issue:4

    Topics: Adenosine Triphosphate; Biopsy; Clofazimine; Dapsone; DNA, Bacterial; Drug Evaluation; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Minocycline; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Rifampin; Sensitivity and Specificity; Treatment Outcome

1999
A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:4

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Colony Count, Microbial; Dapsone; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Leprostatic Agents; Leprosy; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mycobacterium leprae; Ofloxacin; Rifampin

2000
[Multi-drug resistant Mycobacterium leprae from patients with leprosy].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2004, Volume: 73, Issue:3

    Topics: Animals; Base Sequence; Dapsone; DNA Gyrase; DNA-Directed RNA Polymerases; Drug Resistance, Multiple; Humans; Leprostatic Agents; Leprosy; Mutation; Mycobacterium leprae; Ofloxacin; Rifampin

2004
Chemotherapy of leprosy.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Hypersensitivity; India; Leprosy; Minocycline; Nausea; Ofloxacin; Rifampin; Secondary Prevention; Tuberculosis; World Health Organization

2004
Type I reaction in a borderline leprosy case successfully treated with multidrug therapy and ofloxacin.
    International journal of dermatology, 2008, Volume: 47, Issue:10

    Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Drug Therapy, Combination; Glucocorticoids; Humans; Leprostatic Agents; Leprosy, Borderline; Male; Middle Aged; Ofloxacin; Prednisone; Rifampin

2008
Clinical-pathological conference: case 3.
    Head and neck pathology, 2010, Volume: 4, Issue:3

    Topics: Adult; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Immunologic Deficiency Syndromes; Infections; Leishmaniasis; Leprostatic Agents; Leprosy, Multibacillary; Male; Minocycline; Mycobacterium leprae; Ofloxacin; Palate; Prednisone; Rifampin; Strongyloidiasis; Treatment Outcome

2010
Possible mode of emergence for drug-resistant leprosy is revealed by an analysis of samples from Mexico.
    Japanese journal of infectious diseases, 2010, Volume: 63, Issue:6

    Topics: Bacterial Proteins; Dapsone; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Drug Therapy, Combination; Ear, External; Humans; Leprostatic Agents; Leprosy; Mexico; Mutation; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Prevalence; Rifampin; Sequence Analysis, DNA

2010
Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.
    Leprosy review, 2011, Volume: 82, Issue:1

    Topics: Animals; Bacterial Proteins; Biopsy; Clofazimine; Cross-Sectional Studies; Dapsone; Dihydropteroate Synthase; DNA Gyrase; Drug Resistance, Bacterial; Genetic Predisposition to Disease; Humans; Leprostatic Agents; Leprosy; Mice; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Rifampin

2011
Developing new MDT regimens for MB patients; time to test ROM 12 month regimens globally.
    Leprosy review, 2012, Volume: 83, Issue:3

    Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Minocycline; Mycobacterium leprae; Ofloxacin; Patient Compliance; Rifampin; World Health Organization

2012
Is drug-resistant Mycobacterium leprae a real cause for concern?: First approach to molecular monitoring of multibacillary Colombian patients with and without previous leprosy treatment.
    Biomedica : revista del Instituto Nacional de Salud, 2014, Volume: 34 Suppl 1

    Topics: Adolescent; Adult; Bacterial Proteins; Biopsy; Child; Colombia; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Genotype; Humans; Leprostatic Agents; Leprosy, Multibacillary; Male; Middle Aged; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Retrospective Studies; Rifampin; Young Adult

2014
Drug resistance in Mycobacterium leprae from patients with leprosy in China.
    Clinical and experimental dermatology, 2015, Volume: 40, Issue:8

    Topics: Adult; Bacterial Proteins; China; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Female; Humans; Leprostatic Agents; Leprosy; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Prevalence; Rifampin

2015
Leprosy Drug Resistance Surveillance in Colombia: The Experience of a Sentinel Country.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Proteins; Child; Colombia; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Humans; Leprostatic Agents; Leprosy; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Recurrence; Rifampin; Sentinel Surveillance; Skin; Young Adult

2016
qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Bacterial Proteins; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Leprostatic Agents; Leprosy; Microbial Sensitivity Tests; Mycobacterium leprae; Ofloxacin; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Rifampin; Sensitivity and Specificity; Sequence Analysis, DNA; Skin

2017
Leprosy in Nonimmigrant Canadian Man without Travel outside North America, 2014.
    Emerging infectious diseases, 2018, Volume: 24, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Canada; Dapsone; Drug Therapy, Combination; Florida; Humans; Leprostatic Agents; Leprosy; Male; Mycobacterium leprae; Ofloxacin; Rifampin; Travel

2018
Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018, Volume: 24, Issue:12

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Biopsy, Needle; Brazil; Colombia; Dapsone; DNA Gyrase; Drug Resistance, Bacterial; Endemic Diseases; Epidemiological Monitoring; Global Health; Humans; India; Leprosy; Microbial Sensitivity Tests; Mutation; Mycobacterium leprae; Ofloxacin; Polymerase Chain Reaction; Prospective Studies; Recurrence; Rifampin; Sentinel Surveillance; Skin; Surveys and Questionnaires; World Health Organization

2018
Ofloxacin resistance in multibacillary new leprosy cases from Purulia, West Bengal: a threat to effective secondary line treatment for rifampicin-resistant leprosy cases.
    Journal of global antimicrobial resistance, 2022, Volume: 30

    Topics: Animals; Dapsone; Drug Resistance, Bacterial; Leprostatic Agents; Leprosy; Mice; Mycobacterium leprae; Ofloxacin; Rifampin

2022
A prospective case control study of resistance to rifampicin, dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2023, Volume: 37, Issue:2

    Topics: Case-Control Studies; Dapsone; Drug Therapy, Combination; Humans; Hypersensitivity; Leprostatic Agents; Leprosy; Ofloxacin; Rifampin

2023
High frequency of ofloxacin resistance patterns of Mycobacterium leprae from India: An indication to revisit second line anti-leprosy treatment regimen.
    Journal of global antimicrobial resistance, 2023, Volume: 35

    Topics: Cross-Sectional Studies; Dapsone; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; India; Leprostatic Agents; Leprosy; Mycobacterium leprae; Ofloxacin; Rifampin

2023