ofloxacin and clavulanic acid

ofloxacin has been researched along with clavulanic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (34.78)18.2507
2000's10 (43.48)29.6817
2010's4 (17.39)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aparicio, P; Cabronero, MJ; Lurueña, S; Mínguez, F; Prieto, J1
Mancy, C; Plaisance, JJ; Weber, P1
Beaugrand, M; Blaise, M; Levacher, S; Pateron, D; Pourriat, JL; Trinchet, JC1
Boulanger, JC; Fernandez, H; Henry-Suchet, J; Orfila, J; Verhoest, P1
Baker, PD; Fernau, R; Landon, GC; Lipsky, BA1
Martínek, J; Melenovsky, V; Morávek, J; Spicák, J; Závada, F1
Abalos, RM; dela Cruz, EC; Fajardo, TT; Veerasubramanian, P; Villahermosa, LG; Walsh, DS; Walsh, GP1
Léophonte, P; Veyssier, P1
Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H1
Díaz de Tuesta Chow-Quan, AM; Dimas Nuñez, JF; Geijo Martínez, MP; Gómez Criado, C; Herranz, CR; Saiz García, F1
Shmelev, EI1
Berry, V; Hoover, J; Singley, C; Woodnutt, G1
Bory, AM; Chevalier-Evain, V; Mubiayi, N; Orazi, G; Therby, D1
Appelbaum, PC; Clark, CL; Ednie, LM; Kosowska-Shick, K1
Aguilar, L; Alou, L; Echeverría, O; Giménez, MJ; González, N; Martín, JE; Prieto, J; Sevillano, D; Torrico, M; Valdés, L1
Aguilar, L; Alió, JJ; Alou, L; Cafini, F; Giménez, MJ; González, N; Manso, F; Prieto, J; Sevillano, D; Torrico, M1
Debata, NK; Jena, J; Sahoo, RK; Subudhi, E1
Alfandari, S; Bajolet, O; Blanchard, H; Colomb-Cotinat, M; Daniau, C; Dumartin, C; Lecuru, M; Simon, L1

Reviews

1 review(s) available for ofloxacin and clavulanic acid

ArticleYear
[Respiratory fluoroquinolones in the treatment of exacerbations of chronic obstructive lung disease].
    Problemy tuberkuleza i boleznei legkikh, 2004, Issue:12

    Topics: Administration, Oral; Age Factors; Aged; Amoxicillin; Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Fluoroquinolones; Humans; Injections, Intravenous; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Risk Factors; Time Factors

2004

Trials

5 trial(s) available for ofloxacin and clavulanic acid

ArticleYear
Systemic antibiotic therapy prevents bacterial infection in cirrhotic patients with gastrointestinal hemorrhage.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:1 Pt 1

    Topics: Adult; Amoxicillin; Bacterial Infections; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Endoscopy; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male; Middle Aged; Ofloxacin; Prospective Studies

1994
[A new therapeutic strategy using a ofloxacin-amoxicillin-clavulanic acid combination in the treatment of upper gynecologic infections. Apropos of 123 cases].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; Chlamydia Infections; Chlamydia trachomatis; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Drug Tolerance; Endometritis; Female; Follow-Up Studies; Genital Diseases, Female; Humans; Middle Aged; Ofloxacin; Pelvic Inflammatory Disease; Remission Induction; Salpingitis

1994
Antibiotic therapy for diabetic foot infections: comparison of two parenteral-to-oral regimens.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clavulanic Acid; Clavulanic Acids; Diabetic Foot; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Injections, Intravenous; Male; Middle Aged; Ofloxacin; Penicillins; Prospective Studies; Sulbactam; Treatment Outcome

1997
[Levofloxacin in the treatment of community-acquired pneumococcal pneumonia].
    Presse medicale (Paris, France : 1983), 1999, Nov-20, Volume: 28, Issue:36

    Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Clavulanic Acid; Community-Acquired Infections; Drug Therapy, Combination; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pneumonia, Pneumococcal

1999
[Levofloxacin versus beta-lactamic therapy in community acquired pneumonia that requires hospitalization].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:12

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Clavulanic Acid; Community-Acquired Infections; Drug Therapy, Combination; Female; Hospitalization; Humans; Levofloxacin; Male; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome

2002

Other Studies

17 other study(ies) available for ofloxacin and clavulanic acid

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[Influence of bacterial combinations on the post-antibiotic effect].
    Enfermedades infecciosas y microbiologia clinica, 1990, Volume: 8, Issue:4

    Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Microbial Sensitivity Tests; Netilmicin; Ofloxacin; Staphylococcus aureus

1990
[Comparative epidemiology of the resistance of enterobacteriaceae, Staphylococcus and Pseudomonas aeruginosa to fluoroquinolones in an outpatient study].
    Presse medicale (Paris, France : 1983), 1995, Jun-10, Volume: 24, Issue:21

    Topics: Adolescent; Adult; Aged; Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Female; France; Humans; In Vitro Techniques; Male; Middle Aged; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus; Trimethoprim, Sulfamethoxazole Drug Combination

1995
Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:1

    Topics: Amikacin; Amoxicillin; Animals; Anti-Bacterial Agents; Cefoperazone; Clavulanic Acid; Female; Ofloxacin; Pancreas; Pancreatic Juice; Pancreatitis, Acute Necrotizing; Piperacillin; Rats; Rats, Wistar; Taurocholic Acid; Tissue Distribution

1999
Resolution of lepromatous leprosy after a short course of amoxicillin/clavulanic acid, followed by ofloxacin and clofazimine.
    International journal of dermatology, 1999, Volume: 38, Issue:7

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clofazimine; Drug Therapy, Combination; Female; Humans; Leprosy, Lepromatous; Mycobacterium leprae; Ofloxacin; Skin; Treatment Outcome

1999
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
    Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:2

    Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin

2000
Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:3

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Azithromycin; Clavulanic Acid; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae

2005
[Pelvic and abdominal actinomycosis presenting as a parietal mass].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:3 Pt 1

    Topics: Abdominal Abscess; Abdominal Wall; Actinomycosis; Amikacin; Amoxicillin; Anti-Bacterial Agents; Biopsy; Clavulanic Acid; Diagnosis, Differential; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intrauterine Devices; Middle Aged; Ofloxacin; Pelvic Infection; Pelvic Inflammatory Disease; Radiography, Abdominal; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography

2007
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae

2007
Levofloxacin vs. azithromycin pharmacodynamic activity against S. pneumoniae and H. influenzae with decreased susceptibility to amoxicillin/clavulanic acid.
    Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Clavulanic Acid; Computer Simulation; Drug Resistance, Bacterial; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Streptococcus pneumoniae

2007
In vitro killing activity of crevicular concentrations of tinidazole plus common oral antibiotics against high-density mixed inocula of periodontal pathogens in strict anaerobic conditions.
    Journal of periodontology, 2010, Volume: 81, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Clavulanic Acid; Clindamycin; Drug Synergism; Drug Therapy, Combination; Gingival Crevicular Fluid; Humans; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Periodontal Diseases; Tinidazole

2010
Phylogenetic study of metallo-β-lactamase producing multidrug resistant Pseudomonas aeruginosa isolates from burn patients.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8

    Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Burns; Ceftazidime; Ceftriaxone; Cilastatin; Clavulanic Acid; Colistin; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Multiple, Bacterial; Genetic Variation; Humans; Imipenem; Minocycline; Netilmicin; Ofloxacin; Phylogeny; Polymerase Chain Reaction; Pseudomonas aeruginosa; Tigecycline

2015
Evolution of antibiotic treatments for healthcare-associated infections caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae in France.
    Infectious diseases now, 2022, Volume: 52, Issue:7

    Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Cross Infection; Delivery of Health Care; Enterobacteriaceae; Enterobacteriaceae Infections; France; Humans; Nitrofurantoin; Ofloxacin; Penicillins; Urinary Tract Infections

2022