ofloxacin and cilastatin

ofloxacin has been researched along with cilastatin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (47.06)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Baetz, R; Borner, K; Lebahn, K; Lode, H; Olschewski, P; Reinke, M; Sievers, H; Wagner, J; Wiley, E; Wintermantel, M1
Asada, Y; Mitsuya, K; Namura, S; Nishijima, S1
Bolash, NK; Liu, HH; Lynch, RA; McAnany, ME1
Okonogi, K; Tsuchimori, N; Yamazaki, T1
Takazakura, E; Tsuji, H1
Inoue, Y; Maeda, N; Sato, S; Shimomura, Y; Tano, Y; Watanabe, H1
Geddes, A; Härkönen, M; Jacobs, F; Nowotny, I; Schonwald, S; Thaler, M1
Barberán, J; Borja, J; García-Barbal, J; Gomis, M; Khorrami, S; Sánchez, B1
Harada, H; Iwasaki, Y; Minagawa, T; Nagata, K; Nakagawa, M; Nakanishi, M; Natsuhara, A; Takemura, Y1
Boulanger, BR; Fogarty, C; Fowler, C; Kahn, JB; Morgan, N; Oross, M; Tennenberg, A; West, M; Wiesinger, B; Wu, SC1
Hata, K; Hisamori, S; Inoue, T; Ishimaru, H; Katoh, K; Maeda, Y; Maniwa, K; Minaguchi, M; Oida, K; Sakuramoto, M; Taguchi, Y; Tanaka, E; Terada, K1
Kollef, MH; Shorr, AF; Susla, GB1
Jackson, WL; Kollef, MH; Ramage, AS; Shorr, AF; Tennenberg, AM; Wu, SC; Zadeikis, N1
Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ1
Debata, NK; Jena, J; Sahoo, RK; Subudhi, E1

Reviews

1 review(s) available for ofloxacin and cilastatin

ArticleYear
Quinolones for treatment of nosocomial pneumonia: a meta-analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40 Suppl 2

    Topics: Anti-Infective Agents; Cilastatin; Ciprofloxacin; Cross Infection; Humans; Imipenem; Levofloxacin; Meta-Analysis as Topic; Ofloxacin; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic

2005

Trials

6 trial(s) available for ofloxacin and cilastatin

ArticleYear
Prospective randomized clinical trials of new quinolones versus beta-lactam antibiotics in lower respiratory tract infections.
    Scandinavian journal of infectious diseases. Supplementum, 1990, Volume: 68

    Topics: Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Clavulanic Acids; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Ofloxacin; Pneumonia; Prospective Studies; Remission Induction; Respiratory Tract Infections; Sepsis; Ticarcillin

1990
Susceptibility of bacterial isolates from complicated skin and skin structure infections to cefazolin, imipenem-cilastatin, ciprofloxacin and ofloxacin.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Adolescent; Adult; Anti-Infective Agents; Bacteria; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Ofloxacin; Skin Diseases, Bacterial; Soft Tissue Infections

1995
Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Levofloxacin; Middle Aged; Ofloxacin; Protease Inhibitors; Sepsis; Thienamycins

1999
Oral ofloxacin versus parenteral imipenem-cilastatin in the treatment of osteomyelitis.
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 1999, Volume: 12, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chronic Disease; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Ofloxacin; Osteomyelitis; Prospective Studies

1999
Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: a multicenter, prospective, randomized, open-label study.
    Clinical therapeutics, 2003, Volume: 25, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Ciprofloxacin; Cross Infection; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Staphylococcal; Prospective Studies; Pseudomonas aeruginosa

2003
Levofloxacin for treatment of ventilator-associated pneumonia: a subgroup analysis from a randomized trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40 Suppl 2

    Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Cross Infection; Double-Blind Method; Drug Combinations; Drug Resistance, Bacterial; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Thienamycins; Treatment Outcome; Ventilators, Mechanical

2005

Other Studies

10 other study(ies) available for ofloxacin and cilastatin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
The incidence of isolation of methicillin-resistant Staphylococcus aureus (MRSA) strains from skin infections during the past three years (1989-1991).
    The Journal of dermatology, 1993, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteriophage Typing; Child; Cilastatin; Coagulase; Colony Count, Microbial; Drug Resistance, Microbial; Humans; Imipenem; Impetigo; Methicillin Resistance; Middle Aged; Minocycline; Ofloxacin; Pressure Ulcer; Staphylococcal Skin Infections; Staphylococcus aureus

1993
Therapeutic effects of cefozopran against experimental mixed urinary tract infection with Enterococcus faecalis and Pseudomonas aeruginosa in mice.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:3

    Topics: Ampicillin; Animals; Cefozopran; Ceftazidime; Cephalosporins; Cilastatin; Enterococcus faecalis; Female; Gram-Positive Bacterial Infections; Imipenem; Mice; Mice, Inbred CBA; Ofloxacin; Pseudomonas Infections; Urinary Tract Infections

1997
[Legionella pneumonia successfully treated despite late diagnosis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1997, Volume: 35, Issue:5

    Topics: Administration, Oral; Aged; Anti-Infective Agents; Cilastatin; Drug Combinations; Humans; Imipenem; Legionnaires' Disease; Levofloxacin; Male; Ofloxacin; Protease Inhibitors; Thienamycins

1997
Bilateral corneal infection as a complication of laser in situ keratomileusis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:12

    Topics: Adolescent; Cilastatin; Cornea; Corneal Diseases; Corneal Transplantation; Drug Therapy, Combination; Eye Infections, Bacterial; Humans; Imipenem; Injections, Intravenous; Laser Therapy; Male; Ofloxacin; Ointments; Ophthalmic Solutions; Protease Inhibitors; Staphylococcal Infections; Staphylococcus aureus

1997
[Mycobacterium abscessus infection complicated with diabetes mellitus].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Diabetes Complications; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Ofloxacin; Tuberculosis, Pulmonary

2002
[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2003, Volume: 77, Issue:6

    Topics: Aged; Blister; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Lung Diseases, Interstitial; Minocycline; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Pulmonary Emphysema

2003
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
    Surgical infections, 2010, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin

2010
Phylogenetic study of metallo-β-lactamase producing multidrug resistant Pseudomonas aeruginosa isolates from burn patients.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8

    Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Burns; Ceftazidime; Ceftriaxone; Cilastatin; Clavulanic Acid; Colistin; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Multiple, Bacterial; Genetic Variation; Humans; Imipenem; Minocycline; Netilmicin; Ofloxacin; Phylogeny; Polymerase Chain Reaction; Pseudomonas aeruginosa; Tigecycline

2015