ofloxacin has been researched along with carbostyril in 357 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (7.00) | 18.7374 |
| 1990's | 197 (55.18) | 18.2507 |
| 2000's | 99 (27.73) | 29.6817 |
| 2010's | 24 (6.72) | 24.3611 |
| 2020's | 12 (3.36) | 2.80 |
| Authors | Studies |
|---|---|
| Cobbs, CG; Smith, KR | 1 |
| Debbia, EA; Pesce, A; Schito, GC | 1 |
| García, I; Pascual, A; Perea, EJ | 1 |
| Arai, S; Gohara, Y; Kawashima, T; Kuwano, K; Matsu-Ura, I | 1 |
| Hammerschlag, MR; Hyman, CL; Roblin, PM | 1 |
| Bebear, C; Renaudin, H | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 1 |
| Citron, DM; Goldstein, EJ | 1 |
| Jones, RN | 1 |
| Erwin, ME; Jones, RN | 1 |
| Foleno, B; Fu, KP | 1 |
| Borner, E; Borner, K; Lode, H | 1 |
| Ikeda, Y; Saito, H; Sato, K; Tomioka, H | 1 |
| Aoyama, H; Fukuda, H; Hirai, K; Hosaka, M; Tomizawa, H; Yasue, T | 1 |
| Mitsuhashi, S; Wakebe, H | 1 |
| Allen, SD; Baker, CN; Barry, AL; Fuchs, PC; Hardy, DJ; Jorgensen, JH; McLaughlin, JC | 1 |
| Eirei, J; Kawahara, S | 1 |
| Bornigia, S; De Sio, G; Morbiducci, V; Piersimoni, C; Scalise, G | 1 |
| Jabarit-Aldighieri, N; Raoult, D; Torres, H | 1 |
| Kumamoto, Y | 1 |
| Bartlett, RC; Mazens-Sullivan, MF; McCarter, YS | 1 |
| Grosset, JH; Ji, B; Perani, EG; Petinon, C | 1 |
| Liu, YN; Sun, XD; Wang, R; Zhao, HZ | 1 |
| Kobayashi, M; Mashimo, T; Miki, M; Nakata, S; Okabe, K; Onuki, T; Takahashi, O; Yamanaka, H | 1 |
| Forstall, GJ; Knapp, CC; Washington, JA | 1 |
| Bethune, L; King, A; Phillips, I | 1 |
| Chin, NX; Neu, HC | 1 |
| Cserba, I; Csukás, Z; Sztankov, L | 1 |
| Hardy, DJ | 2 |
| Fuchs, PC | 1 |
| Chodosh, S | 1 |
| Grosset, J; Ji, B; Truffot-Pernot, C | 1 |
| Sato, H; Simanjuntak, MT; Tamai, I; Terasaki, T; Tsuji, A | 1 |
| Barry, AL; Fuchs, PC | 3 |
| Azoulay-Dupuis, E; Bergogne-Bérézin, E; Pocidalo, JJ; Vallée, E | 1 |
| Azoulay-Dupuis, E; Bedos, JP; Pocidalo, JJ; Vallée, E | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ | 1 |
| Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y | 1 |
| Gocke, E | 1 |
| Cartwright, FD; Kenny, GE | 4 |
| Kamisaka, K; Kawahara, S; Kibata, M; Matsuyama, T; Mishima, Y; Nagare, J; Nakada, H; Tada, A; Yoshimoto, S | 1 |
| Azoulay-Dupuis, E; Bedos, JP; Hardy, DJ; Pocidalo, JJ; Swanson, RN; Vallée, E | 1 |
| Chu, DT; Clement, JJ; Hardy, DJ; Shipkowitz, NL; Swanson, RN | 1 |
| Esteve, M; Gargallo-Viola, D; Guinea, J; Llovera, S; Roca, X | 1 |
| Heifets, LB; Lindholm-Levy, PJ | 1 |
| Allen, RA; Amyes, SG; Lewin, CS | 1 |
| Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B | 1 |
| Gemeinhardt, A; Janssen, U; Klotz, U; Unseld, E; Ziegler, G | 1 |
| Barnett, G; Carbó, M; de la Torre, R; Segura, J | 1 |
| Matsumoto, F; Morita, M; Takahashi, T | 1 |
| Glupczynski, Y; Grenier, P; Pierard, D; Van der Auwera, P | 1 |
| Chiaradia, V; Mucignat, G; Pascoli, L; Rubli, F; Santini, GF | 1 |
| Kotera, Y; Mitsuhashi, S | 1 |
| Kato, H; Nagata, O; Nakamura, M; Okezaki, E; Terasaki, T; Tsuji, A | 1 |
| Beer, C; Harder, S; Papenburg, A; Shah, PM; Staib, AH; Stille, W | 1 |
| Rehavi, M; Rubinstein, E; Segev, S | 1 |
| Benonisen, E; Dibb, WL; Digranes, A | 1 |
| Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL | 2 |
| Cremer, AW; Felmingham, D; Grüneberg, RN; O'Hare, MD; Ridgway, GL; Robbins, MJ; Wall, RA; Williams, AH | 1 |
| Forth, W | 1 |
| Chin, NX; Figueredo, VM; Neu, HC; Novelli, A | 1 |
| Andrews, JM; Ashby, JP; Matthews, RS; Wise, R | 1 |
| Bebear, C; de Barbeyrac, B; Quentin, C; Renaudin, H | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Nagayama, A; Nakao, T; Taen, H | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Kato, H; Nagata, O; Okezaki, E; Sato, H; Tsuji, A; Yamamoto, S | 1 |
| Nishino, T; Obana, Y | 1 |
| Bellotti, M; Mattina, R; Raimondi, A; Sander, K | 1 |
| Hirose, T; Inoue, M; Ito, Y; Kato, H; Mitsuhashi, S; Okezaki, E | 1 |
| Smith, JT | 2 |
| Neu, HC | 1 |
| Carlyn, CJ; Doyle, LJ; Knapp, CC; Ludwig, MD; Washington, JA | 1 |
| Iwamoto, Y; Miyake, Y; Okuda, K; Suginaka, H; Tsuruda, K | 1 |
| Grosset, J; JI, B; Lounis, N; Truffot-Pernot, C | 1 |
| Fukuyama, M; Imagawa, Y; Kawakami, K; Suda, O | 1 |
| Citron, DM; Goldstein, EJ; Nesbit, CA | 1 |
| Mancy, C; Plaisance, JJ; Weber, P | 1 |
| Jones, RN; Sutton, LD | 1 |
| Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H | 1 |
| Kaatz, GW; Larsson, AJ; Moody, JA; Rotschafer, JC; Walker, KJ; Zabinski, RA | 1 |
| Beskid, G; Prosser, BL | 2 |
| Cormican, MG; Jones, RN; Marshall, SA | 1 |
| Sanders, CC; Thomson, KS | 2 |
| Aoki, M; Goldstein, E; Kunii, O; Ono, Y | 1 |
| el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF | 1 |
| Cherubin, CE; Stratton, CW | 1 |
| Fujita, H; Matsuo, I | 1 |
| Kudo, M; Ohkubo, T; Sawada, Y; Sugawara, K | 1 |
| Bale, MJ; Erwin, ME; Jones, RN | 1 |
| Cynamon, MH; Klemens, SP; Rogge, MC; Sharpe, CA | 1 |
| Horie, M; Nakazawa, H; Nose, N; Saito, K | 1 |
| Houston, AK; Jones, RN | 1 |
| Irifune, K; Ishida, K; Kaku, M; Mizukane, R; Suyama, N; Takemura, H; Tanaka, H; Tomono, K; Usui, T; Yoshida, R | 1 |
| Blanco, MT; Gómez-García, AC; Hurtado, C; Morán, FJ; Pérez-Giraldo, C; Rodríguez-Benito, A | 1 |
| Hammerschlag, MR; Montalban, G; Roblin, PM | 1 |
| Martínez-Martínez, L; Ortega, MC; Perea, EJ; Suárez, AI | 1 |
| Borobio, MV; Conejo, M; Perea, EJ; Ramirez, E; Suarez, AI | 1 |
| Inoue, Y; Jinbo, Y; Kondo, H; Sakamoto, F; Taguchi, M; Tsukamoto, G | 1 |
| Allen, SD; Erwin, ME; Gerlach, EH; Jones, RN; Marshall, SA; Murray, PR; Washington, JA | 1 |
| Banerjee, DK; McDermott-Lancaster, RD | 1 |
| Appelbaum, PC; Jacobs, MR; Pankuch, GA | 1 |
| Croizé, J; Le Noc, D; Le Noc, P | 1 |
| Akashi, A; Arai, S; Furudera, T; Gohara, Y; Kuwano, K; Matsubara, S; Matumoto, M; Tseng, CC | 1 |
| Belliveau, P; Crowe, H; Gousee, G; Nightingale, CH; Quintiliani, R | 1 |
| Neumann, T; Patton, M; Reichart, C; Zenilman, JM | 1 |
| Ahlén, S; Malmborg, AS | 1 |
| Foleno, BD; Fu, KP; Lafredo, SC | 1 |
| Akashi, A; Arai, S; Gohara, Y; Kuwano, K; Nishimoto, M; Oizumi, K; Takeda, K; Yamaguchi, T; Yano, T | 1 |
| Froelich-Ammon, SJ; Gootz, TD; Jefson, MR; McGuirk, PR; Osheroff, N | 1 |
| Mitsuhashi, S; Yoshida, T | 1 |
| Coll, R; Esteve, M; Garcia, J; Gargallo-Viola, D; Guinea, J; Pares, M; Robert, M; Roser, R; Tudela, E; Xicota, MA | 1 |
| Chan, GP; Franzblau, SG; Parrilla, ML | 1 |
| Saito, H; Sato, K; Tomioka, H | 2 |
| Amsterdam, D; Beam, TR; Gorzynski, EA; Mandell, LA; Rotstein, C | 1 |
| Norte, V; Panchal, S; Piddock, LJ | 1 |
| Saito, H; Tomioka, H | 1 |
| Spivey, IM | 1 |
| Allen, SD; Baker, CN; Barry, AL; Fuchs, PC; Hardy, DJ; Jorgensen, JH; Murray, PR; Tenover, FC | 1 |
| Cormican, MG; Jones, RN | 1 |
| Coll, R; Mirelis, B; Miró, E; Navarro, F; Prats, G; Xicota, MA | 1 |
| Berche, P; Gaillot, O | 1 |
| Molinari, G; Schito, GC | 1 |
| Morrissey, I; Smith, JT | 2 |
| Verbist, L; Verhaegen, J | 1 |
| Hara, K; Ishida, K; Kaku, M; Koga, H; Kohno, S; Usui, T | 1 |
| Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K | 1 |
| Asaoka, T; Imamori, K; Maebashi, K; Matsuda, H; Matsumoto, M; Tahara, Y | 1 |
| Asano, T; Haruta, K; Kasuga, Y; Kurata, M; Nakamura, H; Nanba, E | 1 |
| Iakovlev, SV; Iakovlev, VP; Izotova, GN | 1 |
| Arai, T; Kinoshita, T; Nimura, N | 1 |
| Bobin, P; Grosset, J; Ji, B; Lienhardt, C; Traore, I | 1 |
| Cheung, MM; Ho, NK; Kam, KM; Wong, PW | 1 |
| May, T; Portier, H; Proust, A | 1 |
| Amyes, SG; Brown, JC; Jesudason, MV; Shanahan, PM; Thomson, CJ | 1 |
| Dubreuil, L; Houcke, I; Leroy, I | 1 |
| Akahane, K; Kato, M; Nomura, M; Shimoda, K | 1 |
| Chilima, BZ; Okazawa, Y; Tanno, K; Tosaka, M; Yamane, N | 1 |
| Hayakawa, I; Hohmura, M; Hoshino, K; Ishida, H; Kitamura, A; Nishino, T; Sato, K; Tanaka, M | 1 |
| Chambers, HF; Hackbarth, CJ; Kocagöz, T; Nikaido, H; Rosenberg, EY; Unsal, I | 1 |
| Barbara-Burnham, L; Bermudez, LE; Inderlied, CB; Kolonoski, P; Wu, M; Young, LS | 1 |
| Honmura, T; Komori, K; Matsuda, M; Nishimura, I; Nishino, T; Ozaki, M; Tomii, Y; Yamaguchi, R | 1 |
| Hecht, DW; Wexler, HM | 1 |
| Goldstein, EJ | 1 |
| Conejo, MC; García, I; Pascual, A; Perea, EJ; Salvador, J | 1 |
| Kunichan, AD; Mozhokina, GN; Shapatava, MN | 1 |
| Arvieux, C; Avril, JL; Cartier, F; Jacquelinet, C; Michelet, C; Vu, N | 1 |
| Ballesta, S; García, I; Pascual, A; Perea, EJ | 1 |
| Klecak, G; Urbach, F; Urwyler, H | 1 |
| Forbes, PD; Mäkinen, M; Stenbäck, F | 1 |
| Kubota, Y; Matsushima, T; Miyashita, N; Nakajima, M; Niki, Y | 1 |
| Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K | 1 |
| Bernard, FX; Bisch, D; Blanche, F; Cameron, B; Crouzet, J; Ferrero, L; Goniot, A; Lecoq, C; Manse, B; Maton, L; Ratet, N | 1 |
| Choi, EC; Choi, KH; Hong, JS; Kim, SK; Lee, DK; Yoon, SJ | 1 |
| Barry, AL; Brown, SD; Fuchs, PC | 1 |
| Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV | 1 |
| Arakane, K; Hirobe, M; Mashiko, S; Nagano, T; Ryu, A; Umezawa, N | 1 |
| Ambrose, PG; Nightingale, CH; Owens, RC; Quintiliani, R | 1 |
| Förster, C; Günther, T; Rücker, M; Stahlmann, R; Vormann, J | 1 |
| Morrissey, I | 1 |
| George, J; Morrissey, I | 1 |
| Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H | 1 |
| Inui, KI; Ito, T; Tanaka, K; Yano, I | 1 |
| Choi, EC; Kang, JA; Kim, BK; Kim, JH; Kim, JW; Kim, YG; Lee, JH | 1 |
| Hoogkamp-Korstanje, JA | 1 |
| Jones, RN; Pfaller, MA | 1 |
| Bauernfeind, A | 1 |
| Kim, S; Kim, SJ | 1 |
| Goldsmith, CE; Moore, JE; Murphy, PG | 1 |
| Dencer, C; Felmingham, D; Ridgway, GL; Robbins, MJ; Salman, H | 1 |
| Izumi, K; Kawazoe, K; Mikamo, H; Sato, Y; Tamaya, T | 1 |
| Adamantidis, MM; Bordet, R; Caron, JF; Dumotier, BM | 1 |
| Chuck, SK; Jung, R; Martin, SJ; Messick, CR; Meyer, JM; Pendland, SL | 1 |
| Choi, EC; Choi, KH; Kim, BK; Kim, JH; Kim, JW; Lee, JH | 1 |
| Domon, H; Miyazaki, S; Yamaguchi, K; Yoshizumi, S | 1 |
| Hammerschlag, MR; Roblin, PM | 2 |
| Brookings, E; Gray, B; Nix, S; Robinson, A; Swiatlo, E; Waites, K | 1 |
| Callery-D'Amico, S; Cox, CE; Fowler, CL; Kim, SS; King, W; Klimberg, IW | 1 |
| Hoban, DJ; Karlowsky, JA; Zhanel, GG | 1 |
| Edlund, C; Nord, CE; Sabouri, S | 1 |
| Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D | 1 |
| Baumann-Wilschke, I; Förster, C; Rücker, M; Shakibaei, M; Stahlmann, R; Vormann, J | 1 |
| Dorian, M; Grellet, J; Saux, MC | 1 |
| Dorr, MB; Ellison, W; Henry, D; Magner, DJ; Mansfield, DL; Sullivan, J; Talbot, GH | 1 |
| Bébéar, C; Bébéar, CM; Charron, A; de Barbeyrac, B; Dessus-Babus, S | 1 |
| Deschilder, I; Liekens, K; Lontie, M | 1 |
| Hashimoto, Y; Inui, K; Ito, T; Matsuo, Y; Yano, I | 1 |
| Peters, G; Schumacher-Perdreau, F | 1 |
| Barbosa, J; Bergés, R; Sanz-Nebot, V | 1 |
| Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG | 1 |
| Andriukhin, MI; Avdoshin, VL; Derevianko, II; Gabliia, MIu; Khodyreva, LA | 1 |
| Albini, A; Fasani, E; Profumo, A | 1 |
| Giamarellos-Bourboulis, EJ; Giamarellou, H; Grecka, P; Sambatakou, H | 1 |
| Hirayama, F; Ikeda, Y; Kawakita, T; Kuroda, T; Moriguchi, A; Sakurai, N; Sano, M; Uemori, S; Yamamoto, K | 1 |
| Biavasco, F; Mingoia, M; Montanari, MP; Prenna, M; Ripa, S; Varaldo, PE | 1 |
| Anjo, S; Hara, A; Nakamura, M; Sakai, M | 1 |
| Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR | 1 |
| Bhaduri, AP; Chauhan, PM; Pandey, VC; Puri, SK; Shukla, A; Srivastava, S; Srivastava, SK | 1 |
| Araki, H; Minami, S; Mitsuyama, J; Narita, H; Takahata, M; Todo, Y; Watanabe, Y; Yamashiro, Y; Yonezawa, M | 1 |
| Furusawa, M; Kondo, T; Onodera, Y; Tanabe, K | 1 |
| Haraoka, M; Kobayashi, I; Naito, S; Sagiyama, K; Saika, T; Tanaka, M | 1 |
| Fukuda, M; Sasaki, K; Yoshitake, Y | 1 |
| Akaki, T; Kajitani, H; Kawahara, S; Sakatani, M; Sato, K; Tomioka, H | 1 |
| El'kun, GB | 1 |
| Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I | 1 |
| Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S | 1 |
| Akaki, T; Kajitani, H; Sato, K; Shishido, S; Tomioka, H | 1 |
| Akagi, M; Fukuishi, N; Kanoh, R; Matsui, N | 1 |
| Belousov, IuB; Efremenkova, OV; Sokolov, AV; Tishenkova, IF | 1 |
| Drusano, GL | 1 |
| Castell, JV; Morlière, P; Ouédraogo, G; Santus, R | 1 |
| Ahr, HJ; Blotz, A; Blümel, J; Dubertret, L; Michel, L; Moysan, A; Vohr, HW | 1 |
| Eda, T; Hosaka, M; Hoshino, K; Inoue, M; Kaieda, S; Kitasato, H; Kuga, A; Okamoto, R; Sato, Y; Seto, I | 1 |
| Biedenbach, DJ; Jones, RN; Pfaller, MA | 1 |
| Bonner, D; Fung-Tomc, J; Gradelski, E; Kolek, B; Valera, L | 1 |
| Bai, ZZ; Guan, DW; Zhang, QS | 1 |
| Fujie, M; Seo, N; Takigawa, M; Tokura, Y | 1 |
| Iwatsu, M; Kanai, A; Sado, K; Tian, X | 1 |
| Barrett, JF; Chaniewski, S; Frosco, M; Hooper, DC; Lawrence, LE; Ryan, B; Yang, H | 1 |
| Baumann-Wilschke, I; Rücker, M; Shakibaei, M; Stahlmann, R | 1 |
| Barrett, JF; Frosco, M; Ho, H; Lawrence, LE; Mazzucco, CE; Ryan, BM; Warr, G | 1 |
| Appelbaum, PC; Bozdogan, B; Clark, CL; Davies, TA; Dewasse, B; Jacobs, MR; Nagai, K | 1 |
| Schaeffer, AJ | 1 |
| Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y | 1 |
| Bello, A; Kappel, EM; Shakibaei, M; Stahlmann, R | 1 |
| Furuhama, K; Itoh, S; Katoh, M | 1 |
| Frisbee-Hume, S; Ho, DH; LeBlanc, BM; Rolston, KV; Streeter, H | 1 |
| Araake, M; Hara, T; Nishino, T; Watabe, H | 1 |
| Araake, M; Hara, T; Nishino, T; Shimizu, M; Tabata, M; Watabe, H | 1 |
| Araake, M; Maebashi, K; Tani, M; Watabe, H | 1 |
| Firsov, AA; Lubenko, IY; Portnoy, YA; Vostrov, SN; Zinner, SH | 1 |
| Rubinstein, E | 1 |
| Belvedere, A; Boscá, F; Catalfo, A; Cuquerella, MC; De Guidi, G; Miranda, MA | 1 |
| Chiang, SR; Chuang, YC; Ko, WC; Lee, HC; Tang, HJ; Wang, YY | 1 |
| Ameyama, S; Shinmura, Y; Takahata, M | 1 |
| Kim, IS; Kim, MR; Lee, CJ; Lee, MH; Shim, JH | 1 |
| Bachhawat, R; Bush, K; Deziel, MR; Drusano, GL; Dudley, MN; Freeman, C; Jumbe, N; Kahn, JB; Leary, R; Liu, W; Louie, A; Miller, MH; Tam, VH | 1 |
| Ono, C; Tanaka, M | 1 |
| Almer, LS; Balli, DJ; Beyer, JM; Cai, Y; Flamm, RK; Hensey-Rudloff, D; Nilius, AM; Shen, LL | 1 |
| Cars, O; Löwdin, E; Odenholt, I | 1 |
| Kawai, M; Mashima, Y; Mochizuki, H; Yamada, K; Yamada, M | 1 |
| Maĭchuk, IuF | 1 |
| Arakaki, N; Higa, F; Kawakami, K; Koide, M; Saito, A; Shinzato, T; Tateyama, M | 1 |
| Danziger, LH; Gunderson, SM; Hayes, RA; Quinn, JP | 1 |
| Hong, JW; Hu, CQ; Sheng, LS | 1 |
| Chiang, CH; Lu, DW; Tai, MC | 1 |
| Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T | 1 |
| Amin, AS; Ragab, GH | 1 |
| Daschner, F; Schmidt-Eisenlohr, E; Wenzler, S | 1 |
| Bao, L; Long, Y; Wu, YH; Xie, YX; Zeng, XW; Zhang, HD; Zhao, MC | 1 |
| Arzamastsev, AP; Firsov, AA; Lubenko, IY; Portnoy, YA; Vostrov, SN; Zinner, SH | 1 |
| Duan, GC; Xi, YL; Zhu, JY | 1 |
| Naber, KG | 1 |
| Gonoi, T; Saraya, A; Seino, S; Yokokura, M | 1 |
| Boldrini, E; Campa, M; Celandroni, F; Davini, P; Ghelardi, E; Parisio, E; Salvetti, S; Senesi, S; Tavanti, A | 1 |
| Arbogast, PG; Bansal, P; Hargrove, F; Hulgan, T; Kernodle, DS; Miller, RA; Rosenbloom, ST; Talbert, DA | 1 |
| Fish, DN | 1 |
| Hatano, K | 1 |
| Kollef, MH; Shorr, AF; Susla, GB | 1 |
| Hermsen, ED; Hovde, LB; Konstantinides, GN; Rotschafer, JC | 1 |
| Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A | 1 |
| Hasegawa, M; Kobayashi, I; Koyama, H; Matsuzaki, K; Sato, Y; Watabe, E | 1 |
| Alferova, IV; Firsov, AA; Lubenko, IY; Portnoy, YA; Smirnova, MV; Zinner, SH | 1 |
| Michot, JM; Mingeot-Leclercq, MP; Seral, C; Tulkens, PM; Van Bambeke, F | 1 |
| Paramasivan, CN; Rahman, F; Sulochana, S | 1 |
| Abba, M; Donnelly, J; Hussain, B; Shervington, LA | 1 |
| Artemenko, N; Gorelov, A; Perekalina, T; Smelov, V; Smelova, N; Ukleeva, G | 1 |
| Kassab, NM; Kedor-Hackmam, ER; Santoro, MI; Singh, AK | 1 |
| Marchese, A; Roveta, S; Schito, AM; Schito, GC | 1 |
| Hikida, M; Kariyama, R; Kato, Y; Kumon, H; Mikuniya, T; Monden, K | 1 |
| Azadian, BS; Roberts, AP; Talboys, CA | 1 |
| Depta, JP; Pichler, WJ; Schmid, DA | 1 |
| Almyroudis, NG; Segal, BH | 1 |
| Hasan, R; Jabeen, K; Khan, E | 1 |
| Wang, S; Wang, Y; Yu, K | 1 |
| Romero, IC; Saravia, NG; Walker, J | 1 |
| Hirota, K; Kayama, S; Miyake, Y; Murakami, K; Ono, T; Susilowati, H; Viducic, D | 1 |
| Ishikawa, K; Kawai, M; Mochizuki, H; Yamada, M | 1 |
| Pedro-Botet, L; Yu, VL | 1 |
| Carmeli, Y; Dodds, AE; Engemann, JJ; Kanafani, ZA; Kaye, KS; Weber, SG | 1 |
| Black, JA; Moland, ES; Thomson, KS; Wickman, PA | 1 |
| Baeyens, WR; Ouyang, J; Yang, Y; Zhao, H; Zhou, S | 1 |
| Bengoechea, JA; Campos, MA; Morey, P | 1 |
| Ni, YN; Zhang, GW | 1 |
| Andreeva, I; Rafalsky, V; Rjabkova, E | 1 |
| Li, XD; Liu, YC; Xu, WH; Zhang, G; Zou, SC | 1 |
| Black, JA; Hanson, ND; Smith Moland, E; Thomson, KS; Wickman, PA | 1 |
| Inui, K; Kimura, N; Okuda, M | 1 |
| Gualco, L; Marchese, A; Schito, AM; Schito, GC | 1 |
| Breithardt, G; Cakir, Y; Eckardt, L; Engelen, MA; Haverkamp, W; Hilker, E; Milberg, P; Mönnig, G; Osada, N; Ramtin, S; Stypmann, J | 1 |
| Esposito, S; Ianniello, F; Leone, S; Noviello, S | 1 |
| Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F | 1 |
| Cañada-Cañada, F; Espinosa-Mansilla, A; Muñoz de la Peña, A | 1 |
| Fan, Y; Gan, X; Li, S; Qin, W | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Gigliotti, F; Morini, S; Ricci, C; Vaira, D; Zullo, A | 1 |
| Jin, L; Shen, B; Wang, X; Zhao, H | 1 |
| Hatou, S; Minagawa, Y; Yamada, M; Yoshida, J; Yoshida, T | 1 |
| Kozai, S; Ohashi, Y; Sakaki, H; Suzuki, T; Tajika, T; Wada, T | 1 |
| Cochetti, I; Minardi, D; Mingoia, M; Montanari, MP; Muzzonigro, G; Tili, E; Varaldo, PE | 1 |
| Chen, XF; Li, WY; Xuan, CS | 1 |
| Qiao, FX; Sun, HW | 1 |
| Jia, YX; Liu, YM; Tian, W | 1 |
| Izumikawa, K; Kakeya, H; Kamihira, S; Kohno, S; Morinaga, Y; Nakamura, S; Seki, M; Yamamoto, Y; Yanagihara, K | 1 |
| Baeyens, WR; Fei, G; He, L; Huang, C; Ouyang, J; Wang, Y | 1 |
| Alam, MR; Garg, P; Gopinathan, U; Krishnaiah, S; Reddy, AK; Sharma, S | 1 |
| Lin, B | 1 |
| Carda-Broch, S; Esteve-Romero, J; Rambla-Alegre, M | 1 |
| Hsueh, PR; Lee, PI; Yang, JC | 1 |
| Bester, AJ; Chang, LW; Chang, YT; Chung, DT; Ho, ML; Hsu, MC; Kasumba, J; King, CH; Mitha, IH; Perng, RP; van Rensburg, DJ; Wu, RG | 1 |
| Goto, K; Jindo, T; Sanbuissho, A; Suzuki, T; Yabe, K | 1 |
| Andreu, I; Aranda, A; Ariza, A; Blanca-Lopez, N; Doña, I; Mayorga, C; Rosado, A; Torres, MJ | 1 |
| Khawcharoenporn, T; Singh, K; Vasoo, S; Ward, E | 1 |
| Alarcón, E; Audícana, MT; Lobera, T; Longo, N; Muñoz, D; Navarro, B | 1 |
| Kessissoglou, DP; Kljun, J; Polatoglou, E; Psomas, G; Tarushi, A; Turel, I | 1 |
| Arlet, G; Emond, JP; Smati, M; Tankovic, J | 1 |
| Hu, M; Ledesma, KR; Singh, R; Swick, MC; Tam, VH; Yang, Z; Zechiedrich, L | 1 |
| Cullen, IM; Fennell, JP; Flynn, RJ; Grainger, R; Manecksha, RP; McDermott, T; McEvoy, E; Nason, GJ; Thornhill, JA | 1 |
| Cheng, J; Hu, LF; Li, JB; Yang, HF; Ye, Y | 1 |
| García-León, G; Martínez, JL; Sánchez, MB | 1 |
| Hosono, M; Takayanagi, R; Yamada, Y; Yokoyama, H | 1 |
| Chen, X; Han, F; Hu, Y; Lü, Y; Qiu, J; Song, W; Zheng, P; Zhou, F; Zhou, X | 1 |
| Ma, JQ; Ni, YL; Wang, LL; Zhang, J; Zhang, ZQ | 1 |
| Kang, H; Lin, L; Luo, Y; Tu, X; Wu, W; Xie, L; Yue, Z; Zhang, Y | 1 |
| Bodmer, T; Donà, V; Droz, S; Endimiani, A; Hilty, M; Schneider, SC; Tinguely, R | 1 |
| Agubata, CO; Nzekwe, IT; Obitte, NC; Okereke, C; Onoja, RI | 1 |
| Blanco, P; Corona, F; Martínez, JL; Sánchez, MB | 1 |
| De Silva, BCJ; Heo, GJ; Hossain, S; Pathirana, HNKS; Wimalasena, SHMP | 1 |
| Nisha, J; Shanthi, V | 1 |
| Awori, MS; Blazquez, T; Chouinard, L; Gargallo-Viola, D; González Borroto, JI; Smith, SY; Tarragó, C; Zsolt, I | 1 |
| Alrwisan, A; Antonelli, PJ; Wang, X; Winterstein, AG | 1 |
| Antonelli, PJ; Dirain, CO; Karnani, DN | 1 |
| Bandyopadhyay, B; Giri, N; Roy, B; Tousif Ahamed, SK | 1 |
| Andersen, CC; Axford, SB; Stark, MJ | 1 |
| Duque-Yemail, J; Grau-López, L; Palma-Alvarez, RF; Perea-Ortueta, M; Ramos-Quiroga, JA; Robles-Martínez, M; Ros-Cucurull, E | 1 |
| Bhutta, MF; Brennan-Jones, CG; Burton, MJ; Chong, LY; Daw, J; Head, K; Richmond, P; Schilder, AG; Snelling, T; Webster, KE | 1 |
| Chang, C; Chen, T; Li, J; Liu, F; Lu, X; Niwa, O; Wang, Q; Xue, Q; Zhou, T | 1 |
| Antonelli, PJ; Dirain, CO | 1 |
| Asareh Zadegan Dezfuli, A; Farajzadeh Sheikh, A; Keshavarzi, R; Khani, P; Saki, M; Seyed-Mohammadi, S; Shahin, M; Tabasi, M; Veisi, H | 1 |
| Arques, A; Escudero-Oñate, C; Micó, P; Mora, M; Oller, I; Sciscenko, I | 1 |
| Fazaludeen Koya, S; Galea, S; Hasan Farooqui, H; Mehta, A; Selvaraj, S | 1 |
| Fu, D; Geng, J; Jiang, J; Li, B; Lu, L; Ma, L; Meng, F; Qi, H; Shen, J; Sun, S; Yabo, SD | 1 |
| Chen, Y; Cheng, Z; Dai, Y; Hu, X; Li, J; Ma, K; Wang, B; Wu, T; Yang, A; Yang, Q; Yi, Q; Zhang, Y; Zhong, X | 1 |
17 review(s) available for ofloxacin and carbostyril
| Article | Year |
|---|---|
[Sensitivity of Hemophilus strains to fluoroquinolones].
Topics: Drug Resistance, Microbial; Haemophilus; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones | 1991 |
Use of quinolones for the treatment of acute exacerbations of chronic bronchitis.
Topics: Acute Disease; Anti-Infective Agents; Bronchitis; Chronic Disease; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Quinolones | 1991 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1990 |
Oral ciprofloxacin, ofloxacin, and lomefloxacin as alternatives to intravenous antimicrobial therapy.
Topics: Administration, Oral; Anti-Bacterial Agents; Ciprofloxacin; Drug Costs; Drug Tolerance; Female; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Cocci; Humans; Male; Ofloxacin; Quinolones; Treatment Outcome | 1993 |
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; Renal Insufficiency | 1995 |
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Safety; Syndrome | 1996 |
New generations of quinolones: with particular attention to levofloxacin.
Topics: Anti-Infective Agents; Community-Acquired Infections; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones | 1997 |
Levofloxacin and sparfloxacin: new quinolone antibiotics.
Topics: Absorption; Anti-Infective Agents; Bronchitis; Drug Interactions; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Pneumonia; Quinolones; Sinusitis; Skin Diseases; Urinary Tract Infections | 1998 |
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections | 2002 |
Levofloxacin in the treatment of urinary tract infections and prostatitis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections | 2004 |
Levofloxacin: update and perspectives on one of the original 'respiratory quinolones'.
Topics: Animals; Drug Resistance, Microbial; Humans; Levofloxacin; Ofloxacin; Quinolones; Respiratory Tract Infections; Staphylococcal Skin Infections | 2003 |
Quinolones for treatment of nosocomial pneumonia: a meta-analysis.
Topics: Anti-Infective Agents; Cilastatin; Ciprofloxacin; Cross Infection; Humans; Imipenem; Levofloxacin; Meta-Analysis as Topic; Ofloxacin; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic | 2005 |
Legionella: macrolides or quinolones?
Topics: Animals; Anti-Infective Agents; Azithromycin; Clinical Trials as Topic; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2006 |
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic | 2006 |
[Treatment for Helicobacter pylori: current criteria].
Topics: Alkylating Agents; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Helicobacter Infections; Helicobacter pylori; Humans; Italy; Levofloxacin; Metronidazole; Ofloxacin; Practice Guidelines as Topic; Proton Pump Inhibitors; Quinolones; Tinidazole; Treatment Outcome | 2007 |
Quinolone-induced psychosis: an updated review.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Delirium; Humans; Levofloxacin; Ofloxacin; Psychoses, Substance-Induced; Quinolones | 2020 |
Topical versus systemic antibiotics for chronic suppurative otitis media.
Topics: Administration, Topical; Adult; Aminoglycosides; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bias; Child; Chronic Disease; Humans; Ofloxacin; Otitis Media, Suppurative; Quinolones; Randomized Controlled Trials as Topic; Time Factors | 2021 |
17 trial(s) available for ofloxacin and carbostyril
| Article | Year |
|---|---|
[Evaluation of new antitubercular agents--new quinolone agents].
Topics: Antitubercular Agents; Drug Resistance, Microbial; Humans; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Tuberculosis, Pulmonary | 1992 |
Single-dose treatment of female acute uncomplicated cystitis.
Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Cefixime; Cefotaxime; Clinical Protocols; Colony Count, Microbial; Cystitis; Fluoroquinolones; Ofloxacin; Quinolones; Recurrence; Treatment Outcome; Urine | 1992 |
Comparison of serum bactericidal activity of 4 fluoroquinolones in healthy volunteers.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Female; Fluoroquinolones; Gram-Positive Cocci; Humans; Male; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Serum Bactericidal Test | 1992 |
4-quinolones inhibit biotransformation of caffeine.
Topics: Adult; Biotransformation; Caffeine; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Interactions; Enoxacin; Humans; Male; Molecular Structure; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones; Random Allocation; Theophylline | 1988 |
Experimental and clinical studies of sparfloxacin in Mycoplasma pneumoniae infection.
Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Lung; Male; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1995 |
Comparative efficacy of sparfloxacin in comparison with amoxycillin plus ofloxacin in the treatment of community-acquired pneumonia. French Study Group.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Penicillins; Pneumonia, Bacterial; Quinolones | 1996 |
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Urinary Tract Infections | 1998 |
Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chlamydia Infections; Chlamydophila pneumoniae; Chronic Disease; Cough; Double-Blind Method; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Moraxella catarrhalis; Neisseriaceae Infections; Ofloxacin; Placebos; Pneumococcal Infections; Quinolones; Sputum; Staphylococcal Infections; Treatment Outcome | 1998 |
Treatment of community-acquired acute uncomplicated urinary tract infection with sparfloxacin versus ofloxacin. The Sparfloxacin Multi Center UUTI Study Group.
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Community-Acquired Infections; Female; Fluoroquinolones; Humans; Middle Aged; Ofloxacin; Quinolones; Recurrence; Treatment Outcome; Urinary Tract Infections | 1998 |
[Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns].
Topics: Adolescent; Adult; Anti-Infective Agents; Burns; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Pseudomonas Infections; Quinolones; Staphylococcal Infections | 1998 |
[Efficacy of lomefloxacin in treatment of nonspecific inflammatory diseases and in prophylaxis of postoperative complications in urology].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Postoperative Complications; Quinolones; Urinary Tract Infections; Urologic Surgical Procedures | 1998 |
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Male; Middle Aged; Ofloxacin; Quinolones; Sinusitis; Treatment Outcome | 1999 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones | 2000 |
[The importance of fluoroquinolones in treating pneumonia in the elderly].
Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Quinolones; Sputum; Time Factors | 1999 |
Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial.
Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Dioxolanes; Double-Blind Method; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Piperazines; Prospective Studies; Prostatitis; Quinolones | 2007 |
Efficacy and safety of nemonoxacin versus levofloxacin for community-acquired pneumonia.
Topics: Adult; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia; Quinolones; Treatment Outcome | 2010 |
In vitro evaluation of IgE-mediated hypersensitivity reactions to quinolones.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Aza Compounds; Basophil Degranulation Test; Ciprofloxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Immediate; Immunologic Tests; Levofloxacin; Male; Middle Aged; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Radioimmunoassay; Sensitivity and Specificity; Young Adult | 2011 |
323 other study(ies) available for ofloxacin and carbostyril
| Article | Year |
|---|---|
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis | 1992 |
In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Time Factors | 1992 |
Comparative penetration of lomefloxacin and other quinolones into human phagocytes.
Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1992 |
[In vitro antimicrobial activities of new quinolone antibiotics against Mycoplasma pneumoniae].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Macrolides; Mycoplasma pneumoniae; Norfloxacin; Ofloxacin; Quinolones; Tetracyclines | 1992 |
In vitro activities of five quinolones against Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
[In vitro activity of sparfloxacin against mycoplasmas].
Topics: Culture Media; Dose-Response Relationship, Drug; Doxycycline; Drug Resistance, Microbial; Erythromycin; Fluoroquinolones; In Vitro Techniques; Mycoplasma; Mycoplasma fermentans; Mycoplasma pneumoniae; Ofloxacin; Quinolones; Ureaplasma urealyticum | 1992 |
Susceptibilities of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae to RP 59500, vancomycin, erythromycin, PD 131628, sparfloxacin, temafloxacin, win 57273, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Quinolones; Streptococcus pneumoniae; Vancomycin; Virginiamycin | 1992 |
Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1992 |
In vitro evaluation of E-4695, a new fluoro-naphthyridine.
Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro activity of CP-74667 compared with four other fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1992 |
In vitro activity of l-ofloxacin against norfloxacin-resistant coagulase-negative staphylococci.
Topics: Anti-Bacterial Agents; Coagulase; Drug Resistance, Microbial; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus | 1992 |
Determination of sparfloxacin in serum and urine by high-performance liquid chromatography.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Ofloxacin; Quinolones; Spectrometry, Fluorescence | 1992 |
[Antimycobacterial activity of a newly synthesized fluoroquinolone, Y-26611].
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antitubercular Agents; Female; Mice; Mice, Inbred Strains; Mycobacterium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Quinolones | 1992 |
In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Fluoroquinolones; Gatifloxacin; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Tissue Distribution | 1992 |
Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus | 1992 |
Interpretive criteria and quality control parameters for testing susceptibility of Haemophilus influenzae to enoxacin, ofloxacin, and temafloxacin.
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Mutation; Ofloxacin; Quality Control; Quinolones | 1992 |
In vitro activity of the new quinolone lomefloxacin against Mycobacterium tuberculosis.
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1992 |
Susceptibility of Rickettsia conorii, R. rickettsii, and Coxiella burnetii to PD 127,391, PD 131,628, pefloxacin, ofloxacin, and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Coxiella burnetii; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Rickettsia; Rickettsia rickettsii; Viral Plaque Assay | 1992 |
The comparative activity of fleroxacin, three other quinolones and eight unrelated antimicrobial agents.
Topics: Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1992 |
Bactericidal activities of single or multiple doses of various combinations of new antileprosy drugs and/or rifampin against M. leprae in mice.
Topics: Animals; Clarithromycin; Disease Models, Animal; Female; Fluoroquinolones; Foot; Hindlimb; Immunocompetence; Leprostatic Agents; Leprosy; Mice; Microbial Sensitivity Tests; Minocycline; Mycobacterium leprae; Ofloxacin; Quinolones; Rifampin | 1992 |
[Clinical analysis of male urethritis].
Topics: Adolescent; Adult; Child; Gonorrhea; Humans; Japan; Lymphogranuloma Venereum; Male; Middle Aged; Minocycline; Ofloxacin; Penicillins; Quinolones; Retrospective Studies; Sexually Transmitted Diseases; Urethritis | 1991 |
Activity of new quinolones against ciprofloxacin-resistant staphylococci.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus | 1991 |
The in-vitro activity of temafloxacin compared with other antimicrobial agents.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Species Specificity | 1991 |
In-vitro activity of WIN 57273 compared to the activity of other fluoroquinolones and two beta-lactam antibiotics.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1991 |
Activity of temafloxacin and other fluoroquinolones against typical and atypical community-acquired respiratory tract pathogens.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1991 |
In vitro activity of temafloxacin against gram-positive cocci including methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gram-Positive Cocci; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus | 1991 |
In vitro activity of temafloxacin against gram-negative bacteria: an overview.
Topics: Anti-Infective Agents; Campylobacter; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections; Sexually Transmitted Diseases, Bacterial | 1991 |
In vitro and in vivo activities of sparfloxacin (AT-4140) against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Tuberculosis | 1991 |
Transport of the new quinolone antibacterial agents of lomefloxacin and ofloxacin by rat erythrocytes, and its relation to the nicotinic acid transport system.
Topics: Animals; Anti-Infective Agents; Biological Transport, Active; Erythrocytes; Fluoroquinolones; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Niacin; Ofloxacin; Osmolar Concentration; Quinolones; Rats; Rats, Inbred Strains; Temperature | 1991 |
Anti-staphylococcal activity of temafloxacin, ciprofloxacin, ofloxacin and enoxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Oxacillin; Penicillin Resistance; Quinolones; Staphylococcal Infections; Staphylococcus | 1991 |
Pharmacokinetics of four fluoroquinolones in an animal model of infected lung.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Fluoroquinolones; Lung Diseases; Mice; Mice, Inbred Strains; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae | 1991 |
Comparative activity of fluorinated quinolones in acute and subacute Streptococcus pneumoniae pneumonia models: efficacy of temafloxacin.
Topics: Acute Disease; Animals; Anti-Infective Agents; Disease Models, Animal; Female; Fluoroquinolones; Mice; Mice, Inbred Strains; Ofloxacin; Pneumonia; Quinolones; Streptococcus pneumoniae | 1991 |
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones | 1991 |
Cross-resistance and cross-susceptibility between fluoroquinolone agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Predictive Value of Tests; Quinolones | 1991 |
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluation, Preclinical; Enoxacin; Female; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Prodrugs; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Urinary Tract Infections | 1991 |
Mechanism of quinolone mutagenicity in bacteria.
Topics: Anti-Infective Agents; Blotting, Southern; Ciprofloxacin; DNA Topoisomerases, Type II; Enrofloxacin; Escherichia coli; Fleroxacin; Fluoroquinolones; Genes, Bacterial; Mutation; Novobiocin; Ofloxacin; Oxolinic Acid; Quinolones; Salmonella | 1991 |
Susceptibility of Mycoplasma pneumoniae to several new quinolones, tetracycline, and erythromycin.
Topics: Anti-Infective Agents; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Quinolones; Tetracycline | 1991 |
Susceptibilities of Mycoplasma hominis and Ureaplasma urealyticum to two new quinolones, sparfloxacin and WIN 57273.
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Ofloxacin; Quinolones; Tetracycline; Ureaplasma | 1991 |
[In vitro activities of newly developed quinolones, fleroxacin, lomefloxacin and sparfloxacin against Mycobacterium tuberculosis].
Topics: Anti-Infective Agents; Antitubercular Agents; Fleroxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1991 |
Antipneumococcal activity of ciprofloxacin, ofloxacin, and temafloxacin in an experimental mouse pneumonia model at various stages of the disease.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Erythromycin; Female; Fluoroquinolones; Lung; Mice; Mice, Inbred C57BL; Ofloxacin; Pneumonia, Pneumococcal; Quinolones; Sepsis; Streptococcus pneumoniae | 1991 |
Activity of temafloxacin against respiratory pathogens.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Cells, Cultured; Ciprofloxacin; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Gerbillinae; Gram-Positive Bacteria; Guinea Pigs; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1991 |
In vitro and in vivo antibacterial activities of E-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Interactions; Fluoroquinolones; Magnesium; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1991 |
MICs and MBCs of Win 57273 against Mycobacterium avium and M. tuberculosis.
Topics: Anti-Infective Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1990 |
Antibacterial activity of fluoroquinolones in combination with zidovudine.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Salmonella; Staphylococcus; Zidovudine | 1990 |
Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex.
Topics: Adult; Animals; Brain Chemistry; Ciprofloxacin; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Humans; In Vitro Techniques; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Radioligand Assay; Random Allocation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1990 |
Pharmacokinetic determination of relative potency of quinolone inhibition of caffeine disposition.
Topics: Caffeine; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Male; Models, Biological; Norfloxacin; Ofloxacin; Pipemidic Acid; Quinolones | 1990 |
[Therapeutic drug monitoring of fluoroquinolone].
Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum | 1990 |
In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin.
Topics: Aeromonas; Anti-Infective Agents; Campylobacter; Corynebacterium; Enterobacteriaceae; Fluoroquinolones; Haemophilus; Neisseria gonorrhoeae; Ofloxacin; Pefloxacin; Quinolones; Staphylococcus aureus | 1989 |
Ofloxacin: in vitro activity against recently isolated gram-negative bacterial strains.
Topics: Acinetobacter; Anti-Bacterial Agents; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones | 1989 |
In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Phenalenes; Quinolones | 1989 |
Serum protein binding of lomefloxacin, a new antimicrobial agent, and its related quinolones.
Topics: Animals; Anti-Infective Agents; Blood Proteins; Dogs; Fluoroquinolones; Humans; Nalidixic Acid; Ofloxacin; Protein Binding; Quinolones; Rats; Species Specificity | 1989 |
Quinolones, theophylline, and diclofenac interactions with the gamma-aminobutyric acid receptor.
Topics: Animals; Ciprofloxacin; Diclofenac; Drug Synergism; GABA Antagonists; In Vitro Techniques; Male; Muscimol; Nalidixic Acid; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Theophylline | 1988 |
In vitro activities of ciprofloxacin, ofloxacin, norfloxacin and rosoxacin compared with cinoxacin and trimethoprim.
Topics: 4-Quinolones; Acinetobacter; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cinoxacin; Ciprofloxacin; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pseudomonas aeruginosa; Quinolines; Quinolones; Trimethoprim | 1985 |
The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens.
Topics: 4-Quinolones; Aeromonas; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter fetus; Cinoxacin; Ciprofloxacin; Diarrhea; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Intestines; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Salmonella; Shigella; Vibrio cholerae; Vibrio parahaemolyticus; Yersinia enterocolitica | 1985 |
The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae.
Topics: 4-Quinolones; Anti-Infective Agents; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones; Streptococcus pneumoniae | 1985 |
Comparative in vitro studies with 4-quinolone antimicrobials.
Topics: 4-Quinolones; Anti-Infective Agents; Bacteria; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pefloxacin; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1985 |
[Gyrase inhibitor].
Topics: 4-Quinolones; Anti-Bacterial Agents; Bacteria; Cinoxacin; Drug Resistance, Microbial; Humans; Nalidixic Acid; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1985 |
In vitro activity of temafloxacin, a new difluoro quinolone antimicrobial agent.
Topics: Anti-Bacterial Agents; Cefotaxime; Chemical Phenomena; Chemistry; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Hydrogen-Ion Concentration; Imipenem; Magnesium; Ofloxacin; Oxazines; Pseudomonas; Quinolines; Quinolones; Thienamycins | 1988 |
In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Blood Proteins; Cefuroxime; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Haemophilus influenzae; Humans; Ofloxacin; Oxazines; Protein Binding; Pseudomonas aeruginosa; Quinolines; Quinolones; Staphylococcus; Streptococcus; Trimethoprim | 1988 |
[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].
Topics: 4-Quinolones; Anti-Bacterial Agents; Ciprofloxacin; Enoxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Mycoplasmataceae; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Quinolones; Ureaplasma | 1988 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.
Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones | 1988 |
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones | 1988 |
Entry of the new quinolone antibacterial agents of ofloxacin and NY-198 into the central nervous system in rats.
Topics: Animals; Anti-Infective Agents; Blood-Brain Barrier; Brain; Fluoroquinolones; Male; Ofloxacin; Quinolones; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinolones; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Ofloxacin; Pyelonephritis; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1988 |
Pharmacokinetic studies in rats with ofloxacin and MF-934, a new fluorinated quinolone.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Fluoroquinolones; Klebsiella pneumoniae; Ofloxacin; Quinolones; Rats | 1987 |
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones | 1987 |
Frequency and expression of mutational resistance to the 4-quinolone antibacterials.
Topics: 4-Quinolones; Anti-Bacterial Agents; Cinoxacin; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Escherichia coli; Fluoroquinolones; Mutation; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Oxolinic Acid; Pipemidic Acid; Quinolines; Quinolizines; Quinolones | 1986 |
The in-vitro activity of EN 272, a quinolone-7-carboxylic acid, in comparison with other quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones; Structure-Activity Relationship; Urinary Tract Infections | 1985 |
Activities of three investigational fluoroquinolones (BAY y 3118, DU-6859a, and clinafloxacin) against Neisseria gonorrhoeae isolates with diminished susceptibilities to ciprofloxacin and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
In vitro activity of tetracyclines, macrolides, quinolones, clindamycin and metronidazole against periodontopathic bacteria.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Clindamycin; Erythromycin; Fluoroquinolones; Metronidazole; Microbial Sensitivity Tests; Minocycline; Miocamycin; Naphthyridines; Ofloxacin; Porphyromonas gingivalis; Prevotella intermedia; Quinolones; Tetracycline | 1995 |
In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Isomerism; Isoniazid; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Splenomegaly; Survival Rate; Tuberculosis | 1995 |
[In vitro antibacterial activity of balofloxacin (BLFX) against isolates from patients with bacterial enteritis].
Topics: Anti-Infective Agents; Drug Resistance, Microbial; Enteritis; Enterobacteriaceae Infections; Escherichia coli; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Salmonella; Shigella | 1995 |
Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Bites, Human; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Wound Infection | 1995 |
[Comparative epidemiology of the resistance of enterobacteriaceae, Staphylococcus and Pseudomonas aeruginosa to fluoroquinolones in an outpatient study].
Topics: Adolescent; Adult; Aged; Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Female; France; Humans; In Vitro Techniques; Male; Middle Aged; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus; Trimethoprim, Sulfamethoxazole Drug Combination | 1995 |
Suggested modifications for disk diffusion susceptibility testing criteria for levofloxacin and sparfloxacin following tests with a predictor panel of ciprofloxacin-resistant clinical isolates.
Topics: Ciprofloxacin; Diffusion; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Reproducibility of Results | 1995 |
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin | 1995 |
Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones.
Topics: Anaerobiosis; Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus aureus | 1995 |
Multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates.
Topics: Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Cross-resistance analysis for DU-6859a, a new fluoroquinolone, compared to six structurally similar compounds (ciprofloxacin, clinafloxacin, fleroxacin, levofloxacin, ofloxacin, and sparfloxacin).
Topics: Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fleroxacin; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
Dissociated resistance among fluoroquinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones | 1994 |
Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leucocytes.
Topics: Anti-Infective Agents; Ciprofloxacin; Extracellular Space; Fluoroquinolones; Humans; Luminescent Measurements; Neutrophils; Ofloxacin; Quinolones; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease | 1995 |
Assessment of the bactericidal activity of sparfloxacin, ofloxacin, levofloxacin, and other fluoroquinolones compared with selected agents of proven efficacy against Listeria monocytogenes.
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Listeria monocytogenes; Listeriosis; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays | 1994 |
The determination of ofloxacin in human skin tissue by high-performance liquid chromatography and correlation between skin tissue concentration and serum level of ofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Ofloxacin; Quinolones; Skin | 1994 |
Minimum inhibitory concentration quality-control guidelines for biapenem, DU-6859a, FK-037, levofloxacin, grepafloxacin, and ceftizoxime when using various National Committee for Clinical Laboratory Standards susceptibility test methods. Quality Control S
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ceftizoxime; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quality Control; Quinolones; Reference Values; Spiro Compounds; Thienamycins | 1994 |
Activity of levofloxacin in a murine model of tuberculosis.
Topics: Animals; Antitubercular Agents; Culture Media; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Levofloxacin; Lung; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Spleen; Stereoisomerism; Tuberculosis, Pulmonary | 1994 |
Simultaneous determination of benofloxacin, danofloxacin, enrofloxacin and ofloxacin in chicken tissue by high-performance liquid chromatography.
Topics: Animals; Anti-Infective Agents; Bacteria; Biological Assay; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Enrofloxacin; Fluoroquinolones; Liver; Muscles; Ofloxacin; Quinolizines; Quinolones; Spectrometry, Fluorescence | 1994 |
Postantibiotic effect of DU-6859a and levofloxacin as compared with ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Enterococcus faecalis; Escherichia coli; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1994 |
In vitro and in vivo activities of sparfloxacin against Mycoplasma pneumoniae.
Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Levofloxacin; Lung; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1994 |
In-vitro slime production by Staphylococcus epidermidis in presence of subinhibitory concentrations of ciprofloxacin, ofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcus epidermidis | 1994 |
In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones | 1994 |
Comparative in vitro activities of new quinolones against coryneform bacteria.
Topics: Anti-Infective Agents; Ciprofloxacin; Corynebacterium; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Comparative activities of eight quinolones against members of the Bacteroides fragilis group.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterials.
Topics: Animals; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicillin; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcal Infections; Thiazoles; Topoisomerase II Inhibitors | 1994 |
In-vitro comparison of DU-6859a, a novel fluoroquinolone, with other quinolones and oral cephalosporins tested against 5086 recent clinical isolates.
Topics: Anti-Infective Agents; Bacteria, Aerobic; Cefixime; Cefotaxime; Cefuroxime; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Activity of sparfloxacin against Mycobacterium leprae measured by the proportional bactericidal test.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Fluoroquinolones; Leprosy; Mice; Mice, Nude; Microbial Sensitivity Tests; Mycobacterium leprae; Ofloxacin; Quinolones | 1993 |
Susceptibilities of 123 Xanthomonas maltophilia strains to clinafloxacin, PD 131628, PD 138312, PD 140248, ciprofloxacin, and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Xanthomonas | 1994 |
Susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to a new quinolone, OPC 17116.
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum | 1993 |
[Compared antibacterial activity of a new fluoroquinolone, sparfloxacin (AT 4140, RP 64206) and four other fluoroquinolones against 332 strains of enteropathogen bacteria].
Topics: Anti-Infective Agents; Campylobacter jejuni; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Helicobacter pylori; Humans; In Vitro Techniques; Ofloxacin; Pefloxacin; Quinolones; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1993 |
In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Drug Resistance, Microbial; Erythromycin; Female; Fluoroquinolones; Humans; Lung; Mesocricetus; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1993 |
Antibacterial activities of OPC-17116, ofloxacin, and ciprofloxacin against 200 isolates of Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Penicillin Resistance; Piperazines; Quinolones; Tetracycline Resistance | 1993 |
In vitro activity of sparfloxacin compared with ciprofloxacin and ofloxacin against respiratory tract pathogens.
Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections | 1993 |
Induction of resistance of Streptococcus pneumoniae to quinolones in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1993 |
A multicenter study on the comparative in vitro activity of fleroxacin and three other quinolones: an interim report from 27 centers.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Effects of new quinolones on Mycoplasma pneumoniae-infected hamsters.
Topics: Animals; Anti-Infective Agents; Antibodies, Bacterial; Ciprofloxacin; Cricetinae; Female; Fluoroquinolones; Half-Life; Humans; Lung; Mesocricetus; Mycoplasma pneumoniae; Ofloxacin; Pneumonia, Mycoplasma; Quinolones | 1993 |
Novel 1-8-bridged chiral quinolones with activity against topoisomerase II: stereospecificity of the eukaryotic enzyme.
Topics: Animals; Cell Survival; Cells, Cultured; DNA; Drosophila melanogaster; Escherichia coli; Eukaryotic Cells; Ofloxacin; Quinolones; Stereoisomerism; Topoisomerase II Inhibitors | 1993 |
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Dioxolanes; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Topoisomerase II Inhibitors | 1993 |
In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent.
Topics: Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Culture Media; Fleroxacin; Fluoroquinolones; Horses; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Sparfloxacin is more bactericidal than ofloxacin against Mycobacterium leprae in mice.
Topics: Animals; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Ofloxacin; Quinolones | 1993 |
Comparative antimycobacterial activities of the newly synthesized quinolone AM-1155, sparfloxacin, and ofloxacin.
Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Intracellular Fluid; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium chelonae; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Ofloxacin; Piperazines; Quinolones | 1993 |
In vitro activity of sparfloxacin, ciprofloxacin, ofloxacin, and other antibiotics against bloodstream isolates of gram-positive cocci.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1993 |
Comparison of the mechanism of action and resistance of two new fluoroquinolones, rufloxacin and MF961 with those of ofloxacin and fleroxacin in gram-negative and gram-positive bacteria.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Mutation; Ofloxacin; Quinolones; Rec A Recombinases | 1993 |
Therapeutic efficacy of some new quinolones and a combination of ofloxacin with rifampin against Mycobacterium leprae infection induced in athymic nude mice.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Leprosy; Mice; Mice, Inbred BALB C; Mice, Nude; Ofloxacin; Quinolones; Rifampin | 1993 |
[In vitro antimycobacterial activity of a new quinolone, NM394].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Ofloxacin; Piperazines; Quinolones | 1993 |
Criteria for use of ofloxacin and lomefloxacin in adult inpatients and outpatients.
Topics: Adult; Anti-Infective Agents; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Infections; Ofloxacin; Pseudomonas Infections; Quinolones; Respiratory Tract Infections; Urinary Tract Infections | 1993 |
Tentative criteria for confirming the in vitro susceptibilities of Haemophilus influenzae and Neisseria gonorrhoeae to two fluoroquinolones (sparfloxacin and levofloxacin), including quality control parameters.
Topics: Anti-Infective Agents; Fluoroquinolones; Haemophilus influenzae; Levofloxacin; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quality Control; Quinolones | 1993 |
Cross-resistance analysis for clinafloxacin compared with ciprofloxacin, fleroxacin, ofloxacin, and sparfloxacin using a predictor panel of ciprofloxacin-resistant bacteria.
Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro activity of E-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Otitis Media; Quinolones; Sinusitis | 1995 |
Comparative in vitro activity of BAY Y 3118 with other fluoroquinolones.
Topics: Aminoglycosides; Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Quinolones; Spiro Compounds; Streptococcus pneumoniae; Tetracycline | 1995 |
The new 4-quinolones DU-6859a and DV-7751a show enhanced activity against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Culture Media; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds; Streptococcus pneumoniae | 1995 |
Comparative in vitro activity of BAY Y 3118 against selected species.
Topics: Anti-Infective Agents; Bacteria; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones | 1995 |
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones | 1995 |
Flush induced by fluoroquinolones in canine skin.
Topics: Animals; Anti-Infective Agents; Dogs; Female; Fluoroquinolones; Flushing; Histamine Antagonists; Male; Ofloxacin; p-Methoxy-N-methylphenethylamine; Quinolones; Skin | 1995 |
Investigation of enantioselective separation of quinolonecarboxylic acids by capillary zone electrophoresis using vancomycin as a chiral selector.
Topics: Anti-Infective Agents; Electrophoresis, Capillary; Fluoroquinolones; Ofloxacin; Quinolones; Stereoisomerism; Vancomycin | 1996 |
Determination of the minimal effective dosages of ofloxacin and sparfloxacin against M. leprae in the mouse foot pad system.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Foot; Mice; Mycobacterium leprae; Ofloxacin; Quinolones | 1996 |
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluoroquinolones; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Reference Standards | 1996 |
Mutations responsible for reduced susceptibility to 4-quinolones in clinical isolates of multi-resistant Salmonella typhi in India.
Topics: Amino Acid Sequence; Base Sequence; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nalidixic Acid; Ofloxacin; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Quinolones; Salmonella typhi | 1996 |
[In vitro activity of a new fluoroquinolone, marbofloxacin (RO 09-1168) against strictly anaerobic bacteria and some bacteria from human fecal flora].
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Dose-Response Relationship, Drug; Enterococcus; Escherichia coli; Feces; Fluoroquinolones; Humans; In Vitro Techniques; Lactobacillus; Ofloxacin; Proteus; Quinolones; Topoisomerase II Inhibitors | 1996 |
LD50 value, phototoxicity and convulsion induction test of the new quinolone antibacterial agent (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxyl ic acid hemihydrate in la
Topics: Administration, Oral; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Convulsants; Dermatitis, Phototoxic; Female; Fluoroquinolones; Injections, Intravenous; Lethal Dose 50; Macaca fascicularis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Ofloxacin; Phenylacetates; Quinolones; Rats; Rats, Sprague-Dawley | 1996 |
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media].
Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones | 1996 |
Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.
Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Media; Culture Media, Serum-Free; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Kinetics; Levofloxacin; Metals; Microbial Sensitivity Tests; Microscopy, Electron; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Urine | 1996 |
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.
Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones | 1996 |
Susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to a new quinolone, trovafloxacin (CP-99,219).
Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Naphthyridines; Ofloxacin; Quinolones; Ureaplasma urealyticum | 1996 |
Activities of bay Y 3118, levofloxacin, and ofloxacin alone or in combination with ethambutol against Mycobacterium avium complex in vitro, in human macrophages, and in beige mice.
Topics: Animals; Anti-Infective Agents; Cell Line; Drug Combinations; Ethambutol; Female; Fluoroquinolones; Humans; Levofloxacin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rats | 1996 |
Uptake and intracellular activity of NM394, a new quinolone, in human polymorphonuclear leukocytes.
Topics: Amino Acids; Anti-Infective Agents; Antimetabolites; Ciprofloxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Neutrophils; Nucleic Acids; Ofloxacin; Phagocytosis; Piperazines; Pseudomonas aeruginosa; Quinolones | 1996 |
In vitro susceptibility of anaerobes to quinolones in the United States.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Quinolones; United States | 1996 |
Effect of paclitaxel alone or in combination on the intracellular penetration and activity of quinolones in human neutrophils.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cisplatin; Doxorubicin; Fluoroquinolones; Humans; Levofloxacin; Neutrophils; Ofloxacin; Paclitaxel; Quinolones; Staphylococcus aureus | 1996 |
[Effect of drugs of the fluoroquinolone series on morphokinetic parameters of the cellular elements of lung tissue].
Topics: Animals; Anti-Infective Agents; Cell Division; Ciprofloxacin; Culture Techniques; Dogs; Fluoroquinolones; Guinea Pigs; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ofloxacin; Quinolones | 1996 |
Comparative activities of new fluoroquinolones, alone or in combination with amoxicillin, trimethoprim-sulfamethoxazole, or rifampin, against intracellular Listeria monocytogenes.
Topics: Amoxicillin; Anti-Infective Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Fluoroquinolones; HeLa Cells; Humans; Levofloxacin; Listeria monocytogenes; Ofloxacin; Quinolones; Rifampin; Sulfamethoxazole; Trimethoprim | 1997 |
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells].
Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature | 1996 |
Fluoroquinolone antibacterials enhance UVA-induced skin tumors.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Female; Fleroxacin; Fluoroquinolones; Mice; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Quinolones; Skin Neoplasms; Ultraviolet Rays | 1997 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fleroxacin; Fluoroquinolones; Methoxsalen; Mice; Mice, Hairless; Nalidixic Acid; Neoplasms, Radiation-Induced; Ofloxacin; Papilloma; Quinolones; Skin Neoplasms | 1997 |
In vitro and in vivo antichlamydial activities of HSR-903, a new fluoroquinolone antibiotic.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia; Chlamydophila psittaci; Fluoroquinolones; HeLa Cells; Humans; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Minocycline; Ofloxacin; Psittacosis; Quinolones | 1997 |
Antibacterial activities of grepafloxacin, ciprofloxacin, ofloxacin and fleroxacin.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mutation; Ofloxacin; Piperazines; Quinolones | 1997 |
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones.
Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation | 1997 |
Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; DNA Topoisomerase IV; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Fluoroquinolones; Novobiocin; Ofloxacin; Quinolones; Staphylococcus aureus; Substrate Specificity; Topoisomerase II Inhibitors | 1996 |
Sparfloxacin and levofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Drug Eruptions; Fluoroquinolones; Gastrointestinal Diseases; Humans; Levofloxacin; Ofloxacin; Photosensitivity Disorders; Pneumonia; Quinolones | 1997 |
In-vitro and in-vivo activities of DW-116, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Dose-Response Relationship, Drug; Enterococcus faecalis; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicillin Resistance; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus | 1997 |
Is Escherichia coli ATCC 25922 useful for monitoring broth microdilution tests of fluoroquinolones?
Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Reproducibility of Results | 1997 |
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates.
Topics: Animals; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Cats; Ciprofloxacin; Dogs; Fluoroquinolones; Haplorhini; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Swine; Wound Infection | 1997 |
Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA; DNA Damage; Enoxacin; Fluoroquinolones; Free Radical Scavengers; Hematoporphyrins; Molecular Structure; Ofloxacin; Oxygen; Photosensitizing Agents; Quinolones; Reactive Oxygen Species; Spectroscopy, Near-Infrared; Superoxides | 1997 |
In vitro evidence for a Donnan distribution of Mg2+ and Ca2+ by chondroitin sulphate in cartilage.
Topics: Animals; Calcium; Cartilage; Cattle; Chondroitin Sulfates; Dialysis; Diffusion; Magnesium; Ofloxacin; Osmolar Concentration; Quinolones; Sharks; Spectrophotometry, Atomic | 1997 |
Bactericidal index: a new way to assess quinolone bactericidal activity in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Enterococcus faecalis; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones | 1997 |
The bactericidal activity of levofloxacin compared with ofloxacin, D-ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Cefotaxime; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1997 |
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Transport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Epithelial Cells; Epithelium; Fluoroquinolones; Humans; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Quinolones; Swine | 1997 |
In vitro and in vivo antibacterial efficacies of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Culture Media; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1997 |
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections | 1997 |
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcal Infections; Streptococcus; Streptococcus pneumoniae | 1997 |
Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus | 1997 |
Abnormal proteins enhance stress-induced cell death.
Topics: Anti-Infective Agents; Bacterial Proteins; Chaperonins; Enzyme Stability; Escherichia coli; Fluoroquinolones; Methionine-tRNA Ligase; Models, Molecular; Mutation; Ofloxacin; Peptide Fragments; Protein Conformation; Quinolones | 1998 |
Pneumococcal resistance in the UK.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Macrolides; Microbial Sensitivity Tests; Northern Ireland; Ofloxacin; Oxacillin; Penicillin Resistance; Penicillins; Piperazines; Pneumococcal Infections; Quinolones; Retrospective Studies; Streptococcus pneumoniae; Tetracycline | 1997 |
The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia; Clarithromycin; Dose-Response Relationship, Drug; Doxycycline; Fluoroquinolones; Gram-Negative Bacteria; Legionella; Mycoplasma; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum | 1997 |
Therapeutic effects of a new quinolone, DU-6859a, on polymicrobial infections in a newly designed model of rat uterine endometritis.
Topics: Animals; Anti-Infective Agents; Bacteroides fragilis; Disease Models, Animal; Drug Therapy, Combination; Endometritis; Escherichia coli; Female; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Rats; Rats, Sprague-Dawley | 1998 |
Sparfloxacin but not levofloxacin or ofloxacin prolongs cardiac repolarization in rabbit Purkinje fibers.
Topics: Action Potentials; Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Male; Ofloxacin; Purkinje Fibers; Quinolones; Rabbits; Stereoisomerism | 1998 |
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1998 |
In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Respiratory Tract Infections; Streptococcal Infections; Streptococcus pneumoniae | 1998 |
In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Chlamydia Infections; Chlamydophila pneumoniae; Doxycycline; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 1998 |
Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest.
Topics: Anti-Infective Agents; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Streptococcus pneumoniae | 1998 |
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Vancomycin | 1998 |
Comparative in vitro activity of BAY 12-8039 and five other antimicrobial agents against anaerobic bacteria.
Topics: Anti-Infective Agents; Aza Compounds; Bacteria, Anaerobic; Cefoxitin; Cephamycins; Clindamycin; Fluoroquinolones; Imipenem; Metronidazole; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Thienamycins | 1998 |
Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Extremities; Fleroxacin; Fluoroquinolones; Magnesium Deficiency; Mice; Microscopy, Electron; Ofloxacin; Pefloxacin; Quinolones | 1998 |
Uptake of fluoroquinolones in human monocytes isolated from peripheral blood.
Topics: Anti-Infective Agents; Cell Adhesion; Cell Separation; Ciprofloxacin; Flow Cytometry; Fluoroquinolones; Humans; Monocytes; Ofloxacin; Quinolones | 1998 |
The effects of increasing levels of quinolone resistance on in-vitro activity of four quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Quinolones | 1998 |
Sequencing of gyrase and topoisomerase IV quinolone-resistance-determining regions of Chlamydia trachomatis and characterization of quinolone-resistant mutants obtained In vitro.
Topics: Amino Acid Sequence; Anti-Infective Agents; Base Sequence; Chlamydia trachomatis; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Molecular Sequence Data; Mutation; Ofloxacin; Quinolones | 1998 |
In vitro activity of newer quinolones on Streptococcus pneumoniae isolated from outpatients.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Cephalosporins; Doxycycline; Drug Therapy, Combination; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Outpatients; Penicillin G; Penicillins; Piperazines; Pneumococcal Infections; Quinolones; Roxithromycin; Streptococcus pneumoniae | 1998 |
Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC-PK1.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Anti-Infective Agents; Cyclosporine; Epithelial Cells; Fluoroquinolones; Hydrogen-Ion Concentration; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Piperazines; Quinolones; Swine | 1998 |
In-vitro activity of three fluoroquinolones, cefotaxime and clindamycin against staphylococci.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Cephalosporins; Ciprofloxacin; Clindamycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Staphylococcal Infections; Staphylococcus | 1995 |
Retention behaviour of quinolone derivatives in high-performance liquid chromatography. Effect of pH and evaluation of ionization constants.
Topics: Acetonitriles; Anti-Infective Agents; Chromatography, High Pressure Liquid; Enoxacin; Fleroxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Norfloxacin; Ofloxacin; Osmolar Concentration; Potentiometry; Quinolizines; Quinolones; Thermodynamics; Water | 1998 |
Structure and medium-dependent photodecomposition of fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Enoxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Photosensitizing Agents; Quantum Theory; Quinolones; Structure-Activity Relationship | 1998 |
In vitro activity of quinupristin/dalfopristin and newer quinolones combined with gentamicin against resistant isolates of Enterococcus faecalis and Enterococcus faecium.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gentamicins; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Virginiamycin | 1998 |
Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Drug Stability; Fluoroquinolones; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Indicators and Reagents; Microbial Sensitivity Tests; Molecular Structure; Naphthyridines; Ofloxacin; Quinolones; Solutions; Structure-Activity Relationship; Ultraviolet Rays | 1998 |
Antistaphylococcal and antistreptococcal killing kinetics of ciprofloxacin, ofloxacin, sparfloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pneumoniae; Streptococcus pyogenes | 1998 |
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature | 1999 |
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin | 1999 |
Synthesis and methemoglobin toxicity of the amides of 6/7 mono or disubstituted quinolone.
Topics: Amides; Animals; Anti-Infective Agents; Ciprofloxacin; Cytochrome-B(5) Reductase; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Methemoglobin; Methemoglobinemia; Norfloxacin; Ofloxacin; Quinolones; Structure-Activity Relationship | 1999 |
In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Indoles; Injections, Subcutaneous; Isoindoles; Male; Mice; Naphthyridines; Ofloxacin; Quinolones | 1999 |
A conspicuous adaptability to antibiotics in the Escherichia coli mutator strain, dnaQ49.
Topics: Amino Acid Sequence; Ampicillin Resistance; DNA Gyrase; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Escherichia coli; Molecular Sequence Data; Mutation; Ofloxacin; Quinolones; Streptomycin | 1999 |
Genotypic evolution in a quinolone-resistant Neisseria gonorrhoeae isolate from a patient with clinical failure of levofloxacin treatment.
Topics: Adult; Anti-Infective Agents; Chromosomes, Bacterial; DNA, Bacterial; Drug Resistance, Microbial; Genotype; Gonorrhea; Humans; Levofloxacin; Male; Neisseria gonorrhoeae; Ofloxacin; Polymerase Chain Reaction; Quinolones; Treatment Outcome | 1999 |
[The uptake of fluoroquinolone agent drugs by cultured human conjunctival epithelial cells and cultured SIRC rabbit corneal cells].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Conjunctiva; Cornea; Epithelial Cells; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Rabbits | 1999 |
Comparative in vitro antimicrobial activities of the newly synthesized quinolone HSR-903, sitafloxacin (DU-6859a), gatifloxacin (AM-1155), and levofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones | 1999 |
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays | 1999 |
Comparative antimicrobial activities of the newly synthesized quinolone WQ-3034, levofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: 4-Quinolones; Aminopyridines; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Rifamycins | 2000 |
Novel action of quinolones on osteoclast-like cells.
Topics: Animals; Cells, Cultured; Dinoprostone; Histocytochemistry; Male; Mice; Nalidixic Acid; Norfloxacin; Ofloxacin; Osteoclasts; Quinolones; Spleen; Tumor Necrosis Factor-alpha | 1999 |
Fluoroquinolone pharmacodynamics: prospective determination of relationships between exposure and outcome.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Models, Biological; Mutation; Neutropenia; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Rats; Treatment Outcome | 2000 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |
Analyses of cutaneous fluoroquinolones photoreactivity using the integrated model for the differentiation of skin reactions.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents; Biomarkers; Cell Membrane; Enoxacin; Female; Fluoroquinolones; Irritants; Mice; Models, Biological; Ofloxacin; Phenotype; Photosensitizing Agents; Quinolones; Skin | 2000 |
[In vitro antibacterial activity of prulifloxacin, a new oral quinolone, and comparative susceptibility rate at clinical breakpoint MIC].
Topics: Anti-Infective Agents; Bacteria; Dioxolanes; Drug Resistance, Microbial; Fluoroquinolones; Humans; Levofloxacin; Ofloxacin; Piperazines; Quinolones; Respiratory Tract Infections; Sepsis | 2000 |
Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States.
Topics: Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Europe; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; United States | 2001 |
Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; beta-Lactams; Enterobacteriaceae; Enterococcus faecalis; Fluoroquinolones; Indoles; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus; Vancomycin | 2001 |
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ].
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones | 1997 |
Quinolone-photoconjugated major histocompatibility complex class II-binding peptides with lysine are antigenic for T cells mediating murine quinolone photoallergy.
Topics: Amino Acid Sequence; Animals; Antigens; Carrier Proteins; CD4-Positive T-Lymphocytes; Dermatitis, Photoallergic; Histocompatibility Antigens Class II; Immunization; Lysine; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Ofloxacin; Quinolones; T-Lymphocytes | 2001 |
Studies on the uptake and release of fluoroquinolones by disposable contact lenses.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Contact Lenses, Hydrophilic; Disposable Equipment; Drug Delivery Systems; Fluoroquinolones; Norfloxacin; Ofloxacin; Quinolones | 2001 |
Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations.
Topics: Anti-Infective Agents; Aza Compounds; DNA Topoisomerases, Type I; Fluoroquinolones; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Quinolones; Staphylococcus aureus | 2002 |
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Limb Buds; Magnesium; Male; Mice; Mice, Inbred Strains; Ofloxacin; Piperazines; Pregnancy; Quinolones | 2002 |
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Sensitivity and Specificity; Staphylococcus aureus | 2002 |
Single- and multistep selection study of the antipneumococcal activity of BMS-284756 compared to ciprofloxacin, levofloxacin, trovafloxacin and moxifloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Streptococcus pneumoniae | 2002 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Female; Fluoroquinolones; Guinea Pigs; Nalidixic Acid; Ofloxacin; Oxazines; Quinolones; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 2002 |
Effects of the Des-F(6)-quinolone garenoxacin (BMS-284756), in comparison to those of ciprofloxacin and ofloxacin, on joint cartilage in immature rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage Diseases; Cartilage, Articular; Ciprofloxacin; Fluoroquinolones; Indoles; Knee Joint; Ofloxacin; Quinolones; Rats; Rats, Wistar | 2002 |
In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.
Topics: Animals; Anti-Infective Agents; Chromosome Aberrations; Dose-Response Relationship, Drug; Fluoroquinolones; Levofloxacin; Light; Male; Mice; Mice, Hairless; Micronuclei, Chromosome-Defective; Micronucleus Tests; Ofloxacin; Photosensitizing Agents; Quinolones; Skin; Time Factors | 2002 |
Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Sensitivity and Specificity | 2002 |
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dosage Forms; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fleroxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Prodrugs; Quinolones | 2002 |
[In vitro short-term bactericidal activity and accumulation of NM394, the active metabolite of prulifloxacin, for Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa: comparison with ciprofloxacin, levofloxacin, and gatifloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Time Factors | 2002 |
[Inhibitory activity of NM394, the active form of prodrug prulifloxacin against type II topoisomerase from Pseudomonas aeruginosa].
Topics: Anti-Infective Agents; Ciprofloxacin; Dioxolanes; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Fluoroquinolones; Gatifloxacin; Levofloxacin; Ofloxacin; Piperazines; Prodrugs; Pseudomonas aeruginosa; Quinolones; Topoisomerase II Inhibitors | 2002 |
Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters.
Topics: Anti-Bacterial Agents; Area Under Curve; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Time Factors | 2002 |
Reply to: Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Disease Models, Animal; Levofloxacin; Ofloxacin; Penicillin Resistance; Pneumonia, Pneumococcal; Quinolones; Rabbits; Streptococcus pneumoniae | 2003 |
Photochemical properties of ofloxacin involved in oxidative DNA damage: a comparison with rufloxacin.
Topics: Anti-Bacterial Agents; DNA Damage; Fluorescence; Fluoroquinolones; Hydrogen Peroxide; Lasers; Ofloxacin; Oxidation-Reduction; Photochemistry; Quinolones; Time Factors | 2003 |
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2003 |
Inhibitory activities of quinolones against DNA gyrase of Chlamydia pneumoniae.
Topics: Anti-Infective Agents; Aza Compounds; Chlamydophila pneumoniae; DNA Gyrase; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Indoles; Levofloxacin; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Topoisomerase II Inhibitors | 2003 |
Simultaneous measurement of fluoroquinolones in eggs by a combination of supercritical fluid extraction and high pressure liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Ofloxacin; Quinolones; Solvents | 2003 |
Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy.
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Kinetics; Mice; Mice, Inbred ICR; Models, Theoretical; Monte Carlo Method; Mutation; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Time Factors | 2003 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol | 2003 |
In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Blood Proteins; Ciprofloxacin; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Protein Binding; Quinolones; Rats | 2003 |
Postantibiotic, postantibiotic sub-MIC, and subinhibitory effects of PGE-9509924, ciprofloxacin, and levofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae | 2003 |
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones | 2003 |
[Levofloxacin (Tavanic) in the treatment of corneal ulcers].
Topics: Administration, Oral; Anti-Infective Agents; Corneal Ulcer; Drug Administration Schedule; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Quinolones; Treatment Outcome | 2003 |
In vitro and in vivo activity of olamufloxacin (HSR-903) against Legionella spp.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cell Line; Erythromycin; Fluoroquinolones; Guinea Pigs; Half-Life; Legionella; Legionnaires' Disease; Levofloxacin; Macrophages; Male; Mice; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2003 |
In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Topics: Anti-Infective Agents; beta-Lactamases; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Quinolones; Streptococcus pneumoniae | 2004 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones | 2003 |
Corneal and scleral permeability of quinolones--a pharmacokinetics study.
Topics: Administration, Topical; Animals; Aqueous Humor; Cell Membrane Permeability; Cinoxacin; Ciprofloxacin; Conjunctiva; Cornea; Enoxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Rabbits; Sclera; Time Factors; Water | 2003 |
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays | 2004 |
Atomic absorption spectroscopic, conductometric and colorimetric methods for determination of fluoroquinolone antibiotics using ammonium reineckate ion-pair complex formation.
Topics: Absorption; Acetone; Anti-Bacterial Agents; Ciprofloxacin; Colorimetry; Dose-Response Relationship, Drug; Electric Conductivity; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Linear Models; Norfloxacin; Ofloxacin; Quaternary Ammonium Compounds; Quinolones; Salts; Solvents; Spectrophotometry, Atomic; Thiocyanates | 2004 |
Comparative in vitro activities of three new quinolones and azithromycin against aerobic pathogens causing respiratory tract and abdominal wound infections.
Topics: Abdominal Injuries; Anti-Bacterial Agents; Aza Compounds; Azithromycin; Bacteria, Aerobic; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Respiratory Tract Infections; Wound Infection | 2004 |
[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].
Topics: Antibiotics, Antitubercular; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Mutation; Mycobacterium tuberculosis; Ofloxacin; Polymorphism, Single-Stranded Conformational; Quinolones | 2004 |
The in vitro activity of a new fluoroquinolone, ABT-492, against recent clinical isolates of Chlamydia pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Chlamydia Infections; Chlamydophila pneumoniae; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2004 |
ABT492 and levofloxacin: comparison of their pharmacodynamics and their abilities to prevent the selection of resistant Staphylococcus aureus in an in vitro dynamic model.
Topics: Algorithms; Anti-Infective Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Half-Life; Humans; Levofloxacin; Models, Biological; Ofloxacin; Protein Binding; Quinolones; Staphylococcus aureus | 2004 |
[Study on the molecular mechanism of quinolone resistance in Shigellae spp].
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pipemidic Acid; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Quinolones; Shigella | 2004 |
Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Cells, Cultured; Fluoroquinolones; Gatifloxacin; Insulin; Insulin Secretion; Islets of Langerhans; Levofloxacin; Mice; Ofloxacin; Patch-Clamp Techniques; Potassium Channels; Quinolones | 2004 |
A mucoadhesive polymer extracted from tamarind seed improves the intraocular penetration and efficacy of rufloxacin in topical treatment of experimental bacterial keratitis.
Topics: Adhesives; Administration, Topical; Animals; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Colony Count, Microbial; Excipients; Eye; Fluoroquinolones; Keratitis; Mucous Membrane; Ofloxacin; Plant Extracts; Pseudomonas Infections; Quinolones; Rabbits; Seeds; Staphylococcal Infections; Tamarindus | 2004 |
Oral quinolones in hospitalized patients: an evaluation of a computerized decision support intervention.
Topics: Administration, Oral; Ciprofloxacin; Costs and Cost Analysis; Decision Support Systems, Clinical; Fluoroquinolones; Hospital Units; Hospitalization; Humans; Injections, Intravenous; Ofloxacin; Prospective Studies; Quinolones | 2004 |
[Simultaneous determination of quinolones in foods by LC/MS/MS].
Topics: Animals; Chromatography, Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fishes; Fluoroquinolones; Food Analysis; Meat; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization | 2004 |
Mutant prevention concentrations of ABT-492, levofloxacin, moxifloxacin, and gatifloxacin against three common respiratory pathogens.
Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae | 2005 |
Vibrational spectroscopic characterization of fluoroquinolones.
Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water | 2005 |
[Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].
Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Quinolones | 2005 |
Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model.
Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Streptococcus pneumoniae; Time Factors | 2005 |
Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages.
Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Ciprofloxacin; Fluoroquinolones; Heat-Shock Response; Humans; Kinetics; Levofloxacin; Macrophages; Moxifloxacin; Ofloxacin; Quinolines; Quinolones | 2005 |
In vitro activity of fluoroquinolones against Mycobacterium tuberculosis.
Topics: Aza Compounds; Ciprofloxacin; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Quinolines; Quinolones; Sampling Studies; Sensitivity and Specificity | 2005 |
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation.
Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors | 2005 |
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Quinolones | 2005 |
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Models, Chemical; Models, Statistical; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Quinolones; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Temperature; Time Factors | 2006 |
Microbiological rationale for the utilisation of prulifloxacin, a new fluoroquinolone, in the eradication of serious infections caused by Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cystic Fibrosis; Dioxolanes; Drug Resistance, Bacterial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Opportunistic Infections; Piperazines; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Quinolones | 2005 |
Synergistic effect of fosfomycin and fluoroquinolones against Pseudomonas aeruginosa growing in a biofilm.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Drug Synergism; Fluoroquinolones; Fosfomycin; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones | 2005 |
Interactions between 4-quinolone antibacterials and multivalent metal ions.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Metals; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones | 1989 |
In vitro activity of lomefloxacin, a new difluorinated quinolone, against urinary bacterial isolates: comparison with enoxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Urinary Tract Infections | 1989 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes | 2006 |
Antibacterial prophylaxis in patients with cancer and neutropenia.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Drug Resistance, Bacterial; Fever; Humans; Neoplasms; Neutropenia; Ofloxacin; Pseudomonas Infections; Quinolones | 2006 |
Emergence of quinolone-resistant Neisseria gonorrhoeae in Pakistan.
Topics: Adult; Anti-Infective Agents; Communicable Diseases, Emerging; Drug Resistance, Bacterial; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neisseria gonorrhoeae; Ofloxacin; Pakistan; Quinolones; Treatment Outcome | 2006 |
Vibrational spectra study on quinolones antibiotics.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Molecular Structure; Ofloxacin; Quinolones; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vibration | 2006 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro.
Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones | 2005 |
Functional analysis of spoT, relA and dksA genes on quinolone tolerance in Pseudomonas aeruginosa under nongrowing condition.
Topics: Ciprofloxacin; Drug Resistance; Guanosine Tetraphosphate; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones | 2006 |
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution | 2006 |
Differential effects of levofloxacin and ciprofloxacin on the risk for isolation of quinolone-resistant Pseudomonas aeruginosa.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Case-Control Studies; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Levofloxacin; Male; Middle Aged; Ofloxacin; Pseudomonas Infections; Quinolones; Regression Analysis; Retrospective Studies; Risk Factors | 2006 |
In vitro activities of DX-619 and comparison quinolones against gram-positive cocci.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Enterococcus; Fluoroquinolones; Gatifloxacin; Gram-Positive Cocci; In Vitro Techniques; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pyrrolidines; Quinolines; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes | 2006 |
Chiral separation of four fluoroquinolone compounds using capillary electrophoresis with hydroxypropyl-beta-cyclodextrin as chiral selector.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Electrophoresis, Capillary; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Molecular Structure; Ofloxacin; Oxazines; Quinolones; Stereoisomerism | 2006 |
Quinolones sensitize gram-negative bacteria to antimicrobial peptides.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Membrane Permeability; Ciprofloxacin; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 2006 |
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].
Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood | 2006 |
Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Amoxicillin; Anti-Bacterial Agents; China; Chloramphenicol; Chromatography, High Pressure Liquid; Climate; Erythromycin; Hong Kong; Macrolides; Norfloxacin; Ofloxacin; Quinolones; Rivers; Seasons; Seawater; Spectrometry, Mass, Electrospray Ionization; Sulfanilamides; Time Factors; Waste Management; Water Pollutants, Chemical | 2007 |
In vitro development of resistance to DX-619 and other quinolones in enterococci.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gatifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Polymerase Chain Reaction; Pyrrolidines; Quinolines; Quinolones; Sequence Analysis, DNA | 2006 |
Interactions of fluoroquinolone antibacterials, DX-619 and levofloxacin, with creatinine transport by renal organic cation transporter hOCT2.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Cell Line; Creatinine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Levofloxacin; Molecular Structure; Ofloxacin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrrolidines; Quinolones; Transfection | 2006 |
In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance.
Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Ciprofloxacin; Dioxolanes; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Hemolysin Proteins; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Ultraviolet Rays; Urinary Tract Infections | 2007 |
Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Fluoroquinolones; Heart Conduction System; In Vitro Techniques; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Rabbits; Torsades de Pointes | 2007 |
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Staphylococcus aureus; Urinary Tract Infections | 2006 |
Separation of fifteen quinolones by high performance liquid chromatography: application to pharmaceuticals and ofloxacin determination in urine.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Ofloxacin; Pharmaceutical Preparations; Quinolones | 2007 |
A rapid CE-potential gradient detection method for determination of quinolones.
Topics: Animals; Electrophoresis, Capillary; Enoxacin; Fleroxacin; Fluoroquinolones; Methods; Milk; Ofloxacin; Oxazines; Quinolones | 2007 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Determination of ulifloxacin by terbium-sensitized fluorescence with second-order scattering and its applications.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Humans; Indicators and Reagents; Luminescence; Norfloxacin; Ofloxacin; Piperazines; Quinolones; Scattering, Radiation; Spectrometry, Fluorescence; Terbium | 2007 |
Mutations in the quinolone resistance determining region in Staphylococcus epidermidis recovered from conjunctiva and their association with susceptibility to various fluoroquinolones.
Topics: Aza Compounds; Conjunctiva; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gatifloxacin; Genes, MDR; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Staphylococcus epidermidis | 2008 |
Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits.
Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Biological Availability; Disease Progression; Endophthalmitis; Enterococcus faecalis; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Male; Ofloxacin; Ointments; Ophthalmic Solutions; Quinolones; Rabbits | 2008 |
Effects of fluoroquinolones on bacterial adhesion and on preformed biofilm of strains isolated from urinary double J stents.
Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Biofilms; Dose-Response Relationship, Drug; Enterococcus; Escherichia coli; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pseudomonas aeruginosa; Quinolones; Staphylococcus; Stenotrophomonas maltophilia; Stents; Ureteral Calculi | 2008 |
Study of fluorescence characteristics of the charge-transfer reaction of quinolone agents with bromanil.
Topics: Anti-Bacterial Agents; Benzoquinones; Catalysis; Ciprofloxacin; Electrons; Energy Transfer; Models, Biological; Norfloxacin; Ofloxacin; Osmolar Concentration; Quinolones; Solvents; Spectrometry, Fluorescence; Technology, Pharmaceutical; Temperature; Time Factors | 2009 |
Recognition mechanism of water-compatible molecularly imprinted solid-phase extraction and determination of nine quinolones in urine by high performance liquid chromatography.
Topics: Binding Sites; Chromatography, High Pressure Liquid; Computer Simulation; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Methacrylates; Models, Molecular; Ofloxacin; Polymers; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solvents; Water | 2008 |
Determination of quinolone antibiotics in urine by capillary electrophoresis with chemiluminescence detection.
Topics: Anti-Infective Agents; Ciprofloxacin; Electrophoresis, Capillary; Humans; Luminescent Measurements; Molecular Structure; Norfloxacin; Ofloxacin; Quinolones; Sensitivity and Specificity; Solvents | 2008 |
Comparative mutant prevention concentration and mutant selection window of sitafloxacin versus other quinolones using strains of Haemophilus influenzae with decreasing susceptibility to levofloxacin.
Topics: Adaptation, Biological; Anti-Bacterial Agents; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Humans; Levofloxacin; Mutation; Ofloxacin; Quinolones; Selection, Genetic | 2009 |
Enhanced separation of seven quinolones by capillary electrophoresis with silica nanoparticles as additive.
Topics: Buffers; Electrophoresis, Capillary; Fleroxacin; Fluoroquinolones; Gatifloxacin; Nanoparticles; Ofloxacin; Oxazines; Quinolones; Silicon Dioxide | 2009 |
Comparison of in vitro susceptibilities of Gram-positive cocci isolated from ocular infections against the second and fourth generation quinolones at a tertiary eye care centre in South India.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Eye Infections, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacterial Infections; Humans; India; Male; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Retrospective Studies; Staphylococcus; Streptococcus | 2010 |
[Multi-residue determination of 11 quinolones in chicken muscle by high performance liquid chromatography with fluorescence detection].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Residues; Fluorescence; Norfloxacin; Ofloxacin; Poultry Products; Quinolones | 2009 |
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results | 2009 |
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline | 2010 |
Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats.
Topics: Administration, Oral; Aminopyridines; Animals; Anti-Bacterial Agents; Area Under Curve; Cartilage, Articular; Dose-Response Relationship, Drug; Fluoroquinolones; Gene Expression Regulation; Male; Ofloxacin; Pyrrolidines; Quinolones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tissue Distribution | 2010 |
High rates of quinolone resistance among urinary tract infections in the ED.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Bacterial; Emergency Service, Hospital; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Quinolones; Retrospective Studies; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections; Young Adult | 2012 |
Allergy to quinolones: low cross-reactivity to levofloxacin.
Topics: Adult; Aged, 80 and over; Basophils; Cross Reactions; Drug Hypersensitivity; Female; Flow Cytometry; Humans; Hypersensitivity, Immediate; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Skin Tests; Young Adult | 2010 |
Interaction of Zn(II) with quinolone drugs: structure and biological evaluation.
Topics: Animals; Anti-Bacterial Agents; Cattle; Coordination Complexes; Crystallography, X-Ray; DNA; Fluoroquinolones; Humans; Levofloxacin; Models, Molecular; Ofloxacin; Protein Binding; Quinolones; Serum Albumin; Serum Albumin, Bovine; Zinc | 2011 |
In vivo sequential selection of Escherichia coli with topoisomerase- and efflux-mediated misleading quinolone resistance phenotypes.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type I; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Phenotype; Quinolones; Selection, Genetic; Sequence Analysis, DNA | 2012 |
Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli.
Topics: Anti-Bacterial Agents; Area Under Curve; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Gene Deletion; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Polymerase Chain Reaction; Quinolones; Real-Time Polymerase Chain Reaction | 2012 |
Prospective study of antibiotic prophylaxis for prostate biopsy involving >1100 men.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy; Cephalosporins; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fever; Humans; Male; Meropenem; Middle Aged; Ofloxacin; Prospective Studies; Prostate; Prostatic Neoplasms; Quinolones; Sepsis; Thienamycins; Treatment Outcome | 2012 |
Plasmid-mediated quinolone resistance in extended-spectrum-β-lactamase- and AmpC β-lactamase-producing Serratia marcescens in China.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; China; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Ofloxacin; Plasmids; Quinolones; Serratia Infections; Serratia marcescens | 2012 |
The Inactivation of intrinsic antibiotic resistance determinants widens the mutant selection window for quinolones in Stenotrophomonas maltophilia.
Topics: Drug Resistance, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Ofloxacin; Quinolones; Stenotrophomonas maltophilia | 2012 |
Interactions between new quinolone antibacterials and diagnostic drug containing manganese.
Topics: Algorithms; Anti-Bacterial Agents; Chelating Agents; Chemistry, Pharmaceutical; Ciprofloxacin; Drug Interactions; Levofloxacin; Manganese Compounds; Ofloxacin; Quinolones | 2013 |
[Simultaneous determination of clopidol, sulfonamide and quinolone residues in chickens by ultra performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Clopidol; Drug Residues; Enrofloxacin; Fluoroquinolones; Food Contamination; Hexanes; Meat; Norfloxacin; Ofloxacin; Quinolones; Sulfanilamide; Sulfanilamides; Sulfonamides; Tandem Mass Spectrometry | 2013 |
Selective solid-phase extraction of artificial chemicals from milk samples using multiple-template surface molecularly imprinted polymers.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Food Contamination; Milk; Molecular Imprinting; Ofloxacin; Quinolones; Reproducibility of Results; Solid Phase Extraction | 2015 |
[Determination of 25 quinolones in cosmetics by liquid chromatography-tandem mass spectrometry].
Topics: Chromatography, Liquid; Ciprofloxacin; Cosmetics; Drug Residues; Enrofloxacin; Fluoroquinolones; Hexanes; Norfloxacin; Ofloxacin; Quinolones; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland.
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Genitalia, Female; Genitalia, Male; Genotype; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Mycoplasma hominis; Mycoplasma Infections; Ofloxacin; Polymerase Chain Reaction; Quinolones; Ribosomal Proteins; RNA, Ribosomal, 16S; RNA, Ribosomal, 23S; Switzerland; Ureaplasma; Ureaplasma Infections; Ureaplasma urealyticum | 2015 |
Development and evaluation of wound healing hydrogels based on a quinolone, hydroxypropyl methylcellulose and biodegradable microfibres.
Topics: Animals; Biodegradable Plastics; Chemistry, Pharmaceutical; Collagen; Excipients; Hydrogels; Hypromellose Derivatives; Male; Ofloxacin; Particle Size; Quinolones; Rats; Rats, Wistar; Wound Healing | 2016 |
Vitamin K
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biological Transport, Active; Biosensing Techniques; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Humans; Luminescent Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Stenotrophomonas maltophilia; Tetracycline; Vitamin K 3 | 2017 |
Prevalence and characterisation of quinolone resistance genes in Aeromonas spp. isolated from pet turtles in South Korea.
Topics: Aeromonas; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Ofloxacin; Plasmids; Polymerase Chain Reaction; Quinolones; Republic of Korea; Turtles | 2017 |
Characterization of Ofloxacin Interaction with Mutated (A91V) Quinolone Resistance Determining Region of DNA Gyrase in Mycobacterium Leprae through Computational Simulation.
Topics: Algorithms; Bacterial Proteins; Binding Sites; Catalytic Domain; DNA; DNA Gyrase; Drug Resistance, Bacterial; Hydrogen Bonding; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Mycobacterium leprae; Ofloxacin; Quinolones | 2018 |
Studies on articular and general toxicity of orally administered ozenoxacin in juvenile rats and dogs.
Topics: Administration, Oral; Aminopyridines; Animals; Anti-Bacterial Agents; Biomarkers; Cartilage, Articular; Dogs; Female; Humans; Joint Diseases; Male; Ofloxacin; Quinolones; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2018 |
Risk for Tympanic Membrane Perforation After Quinolone Ear Drops for Acute Otitis Externa.
Topics: Adult; Anti-Bacterial Agents; Child; Humans; Ofloxacin; Otitis Externa; Quinolones; Retrospective Studies; Tympanic Membrane; Tympanic Membrane Perforation | 2020 |
Commercial Quinolone Ear Drops Cause Perforations in Intact Rat Tympanic Membranes.
Topics: Animals; Ciprofloxacin; Dexamethasone; Female; Hydrocortisone; Male; Methylprednisolone Hemisuccinate; Middle Ear Ventilation; Neomycin; Ofloxacin; Prostheses and Implants; Quinolones; Random Allocation; Rats; Rats, Sprague-Dawley; Tympanic Membrane; Tympanic Membrane Perforation | 2019 |
Development of quinolone resistance and prevalence of different virulence genes among Shigella flexneri and Shigella dysenteriae in environmental water samples.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; India; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Plasmids; Prevalence; Quinolones; Shigella dysenteriae; Shigella flexneri; Virulence | 2020 |
Standardised antenatal antibiotic regimens and neonatal sepsis-Are we certain we have it right?
Topics: Anti-Bacterial Agents; Female; Humans; Neonatal Sepsis; Ofloxacin; Pregnancy; Quinolones; Urinary Tract Infections | 2020 |
The influence mechanism of the molecular structure on the peak current and peak potential in electrochemical detection of typical quinolone antibiotics.
Topics: Anti-Bacterial Agents; Catalysis; Electrochemical Techniques; Enoxacin; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction; Quinolones; Water; Water Pollutants, Chemical | 2021 |
Effects of quinolone and poloxamer otic suspension on rat tympanic membranes.
Topics: Animals; Anti-Bacterial Agents; Ofloxacin; Poloxamer; Quinolones; Rats; Tympanic Membrane | 2021 |
Occurrence of plasmid-mediated quinolone resistance genes in Pseudomonas aeruginosa strains isolated from clinical specimens in southwest Iran: a multicentral study.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Iran; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Quinolones | 2022 |
EEM-PARAFAC as a convenient methodology to study fluorescent emerging pollutants degradation: (fluoro)quinolones oxidation in different water matrices.
Topics: Anti-Bacterial Agents; Chlorides; Ciprofloxacin; Coloring Agents; Enrofloxacin; Environmental Pollutants; Ferric Compounds; Humic Substances; Hydrogen Peroxide; Iron; Ofloxacin; Oxolinic Acid; Quinolones; Thiabendazole; Wastewater; Water; Water Pollutants, Chemical | 2022 |
Quantifying antibiotic use in typhoid fever in India: a cross-sectional analysis of private sector medical audit data, 2013-2015.
Topics: Anti-Bacterial Agents; Cefixime; Cephalosporins; Child; Cross-Sectional Studies; Drug Prescriptions; Female; Humans; India; Male; Medical Audit; Ofloxacin; Practice Patterns, Physicians'; Private Sector; Quinolones; Typhoid Fever; Young Adult | 2022 |
Occurrence, distribution, and risk assessment of quinolone antibiotics in municipal sewage sludges throughout China.
Topics: Anti-Bacterial Agents; China; Environmental Monitoring; Humans; Moxifloxacin; Ofloxacin; Quinolones; Risk Assessment; Sewage; Water Pollutants, Chemical | 2023 |
Characteristics of antibiotic resistance genes and microbial community distribution in Wanfeng Lake, upper Pearl River, China.
Topics: Animals; Anti-Bacterial Agents; China; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Lakes; Macrolides; Microbiota; Ofloxacin; Quinolones; Rivers; Sulfonamides; Water | 2023 |