ofloxacin and aztreonam

ofloxacin has been researched along with aztreonam in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.50)18.7374
1990's8 (25.00)18.2507
2000's15 (46.88)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhutta, ZA; Farooqui, BJ; Naqvi, SH1
Chan, CY; Cheng, IK; Wong, WT1
Hayran, M; Kocagöz, T; Sener, B; Ustaçelebi, S1
Lingaas, E; Teigen, K1
Appelbaum, PC; Spangler, SK; Tamarree, T1
Butzler, JP; Coignau, H; De Mol, P; Ghysels, G; Goossens, H; Grados, O; Innocent, H; Levy, J1
Bauer, D; Spohr, M; Traub, WH1
Neu, HC1
Flynn, CM; Johnson, DM; Jones, RN1
Blahová, J; Králiková, K; Krcméry, V; Torsová, V1
Ho, SW; Hsueh, PR; Jan, IS; Luh, KT; Teng, LJ1
Aoki, K; Hayashi, M; Kawano, Y; Noma, T; Shikishima, Y; Yoshizawa, I1
Jung, R; Messick, CR; Pendland, SL1
Izumi, S; Maseda, H; Nakae, T; Yamabayashi Ta, TA; Yoneyama, H1
Agraharkar, ML; Gupta, R; Rauf, SJ; Singh, S; Smith, J1
Akama, H; Nakae, T; Saito, K; Yoshihara, E1
Hoshino, K; Kanda, H; Lee, VJ; Nakayama, K; Namba, K; Nitanai, H; Ohtsuka, M; Takemura, M; Watkins, WJ; Yokomizo, Y; Yoshida, K; Zhang, JZ1
Dudley, MN; Griffith, DC; Miller, CE; Nolan, TG; Sabet, M; Senekeo-Effenberger, K1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N1
Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L1
Cattoir, V; Nordmann, P; Poirel, L1
Hanaki, H; Maseda, H; Nakae, T; Sugimura, M1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Girlich, D; Nordmann, P; Poirel, L1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

2 review(s) available for ofloxacin and aztreonam

ArticleYear
New antibiotics: areas of appropriate use.
    The Journal of infectious diseases, 1987, Volume: 155, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Infections; beta-Lactamase Inhibitors; Cephalosporins; Ciprofloxacin; Enoxacin; Humans; Imipenem; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Thienamycins

1987
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for ofloxacin and aztreonam

ArticleYear
A randomised prospective comparison of oral ofloxacin and intraperitoneal vancomycin plus aztreonam in the treatment of bacterial peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD).
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1991, Volume: 11, Issue:1

    Topics: Administration, Oral; Aztreonam; Bacterial Infections; Drug Therapy, Combination; Humans; Ofloxacin; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Vancomycin

1991

Other Studies

29 other study(ies) available for ofloxacin and aztreonam

ArticleYear
Therapy of multidrug resistant typhoid in 58 children.
    Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:2

    Topics: Adolescent; Ampicillin Resistance; Aztreonam; Cefotaxime; Ceftriaxone; Child; Child, Preschool; Chloramphenicol Resistance; Drug Resistance, Microbial; Humans; Infant; Infant, Newborn; Ofloxacin; Salmonella typhi; Trimethoprim, Sulfamethoxazole Drug Combination; Typhoid Fever

1992
[The in vitro activity of ciprofloxacin against clinically-isolated strains of Pseudomonas aeruginosa and comparison with some other antibiotics].
    Mikrobiyoloji bulteni, 1990, Volume: 24, Issue:2

    Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Aztreonam; Ceftriaxone; Ciprofloxacin; Gentamicins; Humans; Ofloxacin; Pseudomonas aeruginosa

1990
In vitro activity of 9 antimicrobial agents against 177 strains of Haemophilus influenzae isolated from hospitalized patients.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1990, Volume: 98, Issue:8

    Topics: Aztreonam; beta-Lactamases; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Norway; Ofloxacin; Time Factors

1990
Susceptibility of 310 nonfermentative gram-negative bacteria to aztreonam, carumonam, ciprofloxacin, ofloxacin and fleroxacin.
    Chemotherapy, 1988, Volume: 34, Issue:1

    Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Fleroxacin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Ofloxacin; Oxazines

1988
Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; Cefpirome; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Leucomycins; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxazines; Quinolines

1985
Intraphagocytic bactericidal activity of ofloxacin compared with that of aztreonam and ceftriaxone against Serratia marcescens.
    Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1986, Volume: 261, Issue:1

    Topics: Aztreonam; Ceftriaxone; Escherichia coli; Humans; Ofloxacin; Oxazines; Phagocytes; Phagocytosis; Rifampin; Serratia marcescens

1986
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains.
    Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin

1996
Transfer of antibiotic resistance and production of extended-spectrum beta-lactamase (ESBL) in nosocomial Klebsiella pneumoniae strains from two hospitals in Czech Republic.
    Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1997, Volume: 286, Issue:4

    Topics: Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Cephalothin; Czech Republic; Hospitals; Humans; Klebsiella Infections; Klebsiella pneumoniae; Ofloxacin

1997
Antimicrobial susceptibility testing for Klebsiella pneumoniae isolates resistant to extended-spectrum beta-lactam antibiotics.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1998, Volume: 97, Issue:10

    Topics: Anti-Infective Agents; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Ciprofloxacin; Imipenem; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Monobactams; Ofloxacin; Thienamycins

1998
A comparative investigation of the restorative effects of roxithromycin on neutrophil activities.
    International journal of immunopharmacology, 1998, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Blood Bactericidal Activity; Cefaclor; Cephalosporins; Child; Disabled Persons; Drug Interactions; Female; Flow Cytometry; Humans; Hydrogen Peroxide; Macrophage-1 Antigen; Male; Monobactams; Neutrophils; Ofloxacin; Phagocytosis; Roxithromycin

1998
In vitro synergy testing of levofloxacin, ofloxacin, and ciprofloxacin in combination with aztreonam, ceftazidime, or piperacillin against Pseudomonas aeruginosa.
    Diagnostic microbiology and infectious disease, 2002, Volume: 42, Issue:1

    Topics: Anti-Infective Agents; Aztreonam; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Synergism; Humans; Lactams; Levofloxacin; Microbial Sensitivity Tests; Monobactams; Ofloxacin; Penicillins; Piperacillin; Pseudomonas aeruginosa

2002
Secondary-site mutation restores the transport defect caused by the transmembrane domain mutation of the xenobiotic transporter MexB in Pseudomonas aeruginosa.
    Biochemical and biophysical research communications, 2002, Mar-29, Volume: 292, Issue:2

    Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Outer Membrane Proteins; Biological Transport; Carrier Proteins; Chloramphenicol; Drug Resistance, Bacterial; Kinetics; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Mutation; Ofloxacin; Protein Structure, Tertiary; Pseudomonas aeruginosa; Transformation, Bacterial; Xenobiotics

2002
Sepsis in a renal transplant recipient due to Citrobacter braakii.
    Southern medical journal, 2003, Volume: 96, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Bacteremia; Cellulitis; Citrobacter freundii; Diabetes Mellitus, Type 1; Drug Resistance; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Transplantation; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Opportunistic Infections; Serotyping; Transplantation Immunology; Treatment Outcome

2003
Mutations affecting DNA-binding activity of the MexR repressor of mexR-mexA-mexB-oprM operon expression.
    Journal of bacteriology, 2003, Volume: 185, Issue:20

    Topics: Aztreonam; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; DNA, Bacterial; Drug Resistance, Multiple; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Mutation; Ofloxacin; Operon; Pseudomonas aeruginosa; Repressor Proteins

2003
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: exploration of aromatic substituents.
    Bioorganic & medicinal chemistry, 2006, Dec-15, Volume: 14, Issue:24

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Outer Membrane Proteins; Levofloxacin; Lung; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pyrimidines; Rats; Rats, Sprague-Dawley

2006
Efficacy of aerosol MP-376, a levofloxacin inhalation solution, in models of mouse lung infection due to Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Aztreonam; Disease Models, Animal; Female; Levofloxacin; Lung Diseases; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2009
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal

2007
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey

2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids

2008
Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Outer Membrane Proteins; Down-Regulation; Humans; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2008
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012