ofloxacin has been researched along with acetaminophen in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Nakanishi, S; Okuno, H | 1 |
| Chinh, MT; Day, NP; Diep, TS; Farrar, JJ; Hanh, VT; House, D; Parry, CM; Tham, CT; Thao, NT; Vinh, H; Wain, J; White, NJ | 1 |
| Brain, RA; Hanson, ML; Johnson, DJ; Lam, MW; Mabury, SA; Richards, SM; Sanderson, H; Sibley, PK; Solomon, KR; Young, C | 1 |
| Hara, H; Yokoyama, A | 1 |
| Aberer, W; Arbab, E; Grims, R; Komericki, P; Kränke, B | 1 |
| Dumka, VK | 1 |
| Bleumink, R; Boon, L; Fiechter, D; Hassing, I; Kwast, LM; Ludwig, IS; Pieters, RH | 1 |
| Chen, JL; Chen, TS; Huang, KL | 1 |
| Kim, S; Koyanagi, T; Yamaura, Y; Yamazaki, H; Yano, K | 1 |
| Bleumink, R; Bol-Schoenmakers, M; Fiechter, D; Kruijssen, L; Kwast, L; Ludwig, I; Pieters, R; Smit, J | 1 |
| Clark, S; Clees, WI; Elkin, KR; Elliott, HA; Hayden, KR; Jones, M; Mashtare, ML; Preisendanz, HE; Read, AF; Richard, TL; Shreve, MJ; Silverman, J; Veith, TL; Watson, JE | 1 |
| Farias, MAS; Fatibello-Filho, O; Moraes, FC; Santos, AM; Silva, RMS; Wong, A | 1 |
| Dong, J; Ji, Y; Kong, D; Lu, J; Zhang, C; Zhang, T; Zhou, Q | 1 |
1 review(s) available for ofloxacin and acetaminophen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for ofloxacin and acetaminophen
| Article | Year |
|---|---|
Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever.
Topics: Acetaminophen; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Child; Double-Blind Method; Female; Humans; Ibuprofen; Male; Ofloxacin; Statistics, Nonparametric; Treatment Outcome; Typhoid Fever | 2004 |
Disposition kinetics and dosage regimen of levofloxacin on concomitant administration with paracetamol in crossbred calves.
Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Drug Therapy, Combination; Half-Life; Hybridization, Genetic; Injections, Intravenous; Levofloxacin; Male; Ofloxacin; Time Factors | 2007 |
23 other study(ies) available for ofloxacin and acetaminophen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of inhibitory effects of new quinolones on drug metabolizing activity in the liver.
Topics: Acetaminophen; Animals; Anti-Infective Agents; Enoxacin; Glutathione; Liver; Liver Function Tests; Male; Microsomes, Liver; Mixed Function Oxygenases; Norfloxacin; Ofloxacin; Rats; Theophylline | 1990 |
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical | 2004 |
Multiple fixed drug eruption due to drug combination.
Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caffeine; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Patch Tests; Promethazine; Salicylamides | 2005 |
Tryptase as severity marker in drug provocation tests.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Diclofenac; Drug Hypersensitivity; Female; Humans; Lidocaine; Male; Mefenamic Acid; Middle Aged; Ofloxacin; Penicillins; Prospective Studies; Serine Endopeptidases; Tryptases | 2006 |
Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA.
Topics: Acetaminophen; Acetanilides; Adjuvants, Immunologic; Administration, Oral; Animals; Antibody Formation; Carbamazepine; Drug Evaluation, Preclinical; Drug Hypersensitivity; Female; Injections, Epidural; Local Lymph Node Assay; Metformin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Ofloxacin; Ovalbumin | 2011 |
An electrochemical approach to simultaneous determination of acetaminophen and ofloxacin.
Topics: Acetaminophen; Electrochemical Techniques; Electrodes; Environmental Monitoring; Environmental Pollutants; Ofloxacin | 2012 |
Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs.
Topics: Acetaminophen; Age Factors; Aging; Albumins; Animals; Antipyrine; Blood Proteins; Diazepam; Diphenhydramine; Dogs; Gastric Juice; Hydrogen-Ion Concentration; Macaca fascicularis; Male; Models, Animal; Ofloxacin | 2014 |
Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.
Topics: Acetaminophen; Adaptive Immunity; Administration, Oral; Animals; Carbamazepine; Cells, Cultured; Diclofenac; Drug Hypersensitivity; Female; Humans; Immunity, Innate; Immunologic Factors; Immunologic Memory; Killer Cells, Natural; Liver; Mice; Mice, Inbred C3H; Ofloxacin; Spleen; T-Lymphocytes | 2016 |
Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania.
Topics: Acetaminophen; Ampicillin; Animals; Anti-Bacterial Agents; COVID-19; Dexamethasone; Doxycycline; Environmental Monitoring; Humans; Hydroxychloroquine; Naproxen; Ofloxacin; Pandemics; Pennsylvania; Pharmaceutical Preparations; Soil; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical | 2022 |
Determination of ofloxacin in the presence of dopamine, paracetamol, and caffeine using a glassy carbon electrode based on carbon nanomaterials and gold nanoparticles.
Topics: Acetaminophen; Caffeine; Carbon; Chitosan; Dopamine; Electrodes; Gold; Graphite; Metal Nanoparticles; Ofloxacin; Pharmaceutical Preparations; Water | 2022 |
Photo-transformation of acetaminophen sensitized by fluoroquinolones in the presence of bromide.
Topics: Acetaminophen; Bromides; Bromine; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Water Pollutants, Chemical | 2023 |