ofloxacin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ofloxacin has been researched along with 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (53.33)18.2507
2000's6 (40.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bera, S; Mondal, D1
Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H1
Akaki, T; Sato, K; Tomioka, H2
Akaki, T; Kawahara, S; Sato, K; Shimizu, T; Tomioka, H1
Maw, WW; Saito, H; Sato, K; Tomioka, H1
Duncan, K1
Sato, K; Tomioka, H1
Akaki, T; Ogasawara, K; Sato, K; Tomioka, H1
Akaki, T; Kajitani, H; Sato, K; Shishido, S; Tomioka, H1
Dhople, AM1
Akaki, T; Kawahara, S; Sato, K; Tomioka, H1
Sano, C; Sano, K; Sato, K; Shimizu, T; Tomioka, H1
Hammerschlag, MR; Kutlin, A; Reznik, T; Roblin, PM1
Murphy, CK; Osburne, MS; Rothstein, DM1

Reviews

3 review(s) available for ofloxacin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ArticleYear
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
The impact of genomics on the search for novel tuberculosis drugs.
    Novartis Foundation symposium, 1998, Volume: 217

    Topics: Acetamides; Antitubercular Agents; Drug Design; Genome, Bacterial; Mycobacterium tuberculosis; Ofloxacin; Oxazoles; Rifamycins

1998
[In vitro antimicrobial activities of quinolones, rifamycins and macrolides against Mycobacterium tuberculosis and M.avium complex: attempt to establish new assay methods which accurately reflect therapeutic effects of test agents in vivo].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Rifamycins

1999

Other Studies

12 other study(ies) available for ofloxacin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ArticleYear
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1995, Volume: 76, Issue:1

    Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin

1995
[Anti-Mycobacterium avium complex activities of KRM-1648, clarithromycin and levofloxacin in 7HSF medium at peak or average blood concentrations after their oral administration of clinical dosages].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:7

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Clarithromycin; Culture Media; Humans; Levofloxacin; Mycobacterium avium Complex; Ofloxacin; Rifamycins

1997
[In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Clarithromycin; Diclofenac; Drug Therapy, Combination; Female; Levofloxacin; Mice; Mice, Inbred BALB C; Mycobacterium avium; Ofloxacin; Rifamycins; Tuberculosis

1997
Studies on therapeutic activity of benzoxazinorifamycin KRM-1648 in combination with other antimicrobial agents and biological response modifiers interferon-gamma and granulocyte-macrophage colony-stimulating factor against M. leprae infection in athymic
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1997, Volume: 65, Issue:3

    Topics: Adoptive Transfer; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunologic Factors; Interferon-gamma; Leprostatic Agents; Leprosy; Mice; Mice, Inbred BALB C; Mice, Nude; Ofloxacin; Rifamycins

1997
Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Female; Levofloxacin; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Phagocytosis; Rifamycins; Tuberculosis

1998
[MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins

1999
Comparative antimicrobial activities of the newly synthesized quinolone WQ-3034, levofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:2

    Topics: 4-Quinolones; Aminopyridines; Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Quinolones; Rifamycins

2000
In vitro activity of KRM-1648, either singly or in combination with ofloxacin, against Mycobacterium ulcerans.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:1

    Topics: Anti-Infective Agents; Antibiotics, Antitubercular; Drug Interactions; Humans; Microbial Sensitivity Tests; Mycobacterium ulcerans; Ofloxacin; Rifamycins

2001
Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins; Tuberculosis

2000
Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Rifamycins

2002
In vitro activities of rifamycin derivatives ABI-1648 (Rifalazil, KRM-1648), ABI-1657, and ABI-1131 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rifamycins

2003
Enhanced activity of rifalazil in combination with levofloxacin, linezolid, or mupirocin against Staphylococcus aureus in vitro.
    The Journal of antibiotics, 2006, Volume: 59, Issue:5

    Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Therapy, Combination; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Mupirocin; Ofloxacin; Oxazolidinones; Rifamycins; Staphylococcus aureus

2006