octoclothepine and octoclothepine, (s)-isomer

octoclothepine has been researched along with octoclothepine, (s)-isomer in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnt, J; Bøgesø, KP; Hyttel, J; Liljefors, T; Pedersen, H1
Bøgesø, KP; Liljefors, T1
Butini, S; Cagnotto, A; Campiani, G; Carminati, P; Castorina, M; Catalanotti, B; Di Cesare, MA; Fattorusso, C; Galletti, B; Gemma, S; Ghirardi, O; Giorgi, G; Goegan, M; Mastroianni, D; Mennini, T; Minetti, P; Nacci, V; Pacifici, L; Scafetta, N; Stasi, MA; Tinti, O1
Balle, T; Bang-Andersen, B; Christoffersen, CT; Jensen, M; Kristensen, JL; Püschl, A; Risgaard, R1

Other Studies

4 other study(ies) available for octoclothepine and octoclothepine, (s)-isomer

ArticleYear
Octoclothepin enantiomers. A reinvestigation of their biochemical and pharmacological activity in relation to a new receptor-interaction model for dopamine D-2 receptor antagonists.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Antipsychotic Agents; Chemical Phenomena; Chemistry; Computer Simulation; Corpus Striatum; Dibenzothiepins; Dopamine Antagonists; Mice; Rats; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1991
Conformational analysis and structural comparisons of (1R,3S)-(+)- and (1S,3R)-(-)-tefludazine, (S)-(+)- and (R)-(-)-octoclothepin, and (+)-dexclamol in relation to dopamine receptor antagonism and amine-uptake inhibition.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Antipsychotic Agents; Dibenzocycloheptenes; Dibenzothiepins; Dopamine; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship

1988
Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Catalepsy; Crystallography, X-Ray; Dopamine; Dopamine Antagonists; Homovanillic Acid; In Vitro Techniques; Male; Mice; Microdialysis; Models, Molecular; Molecular Conformation; Molecular Structure; Prolactin; Pyrroles; Radioligand Assay; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship; Thiazepines

2002
Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for α(1)-adrenoceptors.
    Journal of medicinal chemistry, 2010, Oct-14, Volume: 53, Issue:19

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Cattle; Cell Line; Cell Membrane Permeability; Cerebral Cortex; Cricetinae; Crystallography, X-Ray; Dibenzothiepins; Humans; Ligands; Models, Molecular; Piperazines; Positron-Emission Tomography; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Stereoisomerism; Structure-Activity Relationship

2010