obidoxime chloride has been researched along with pralidoxime chloride in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bedford, CD; Goff, DA; Harris, RN; Howd, RA; Koolpe, GA; Miller, A; Musallam, HA; Nolen, HW; Petesch, M; Pick, RO | 1 |
| Bedford, CD; Harris, RN; Howd, RA; Kenley, RA; Miller, A; Nolen, HW | 1 |
| Bielavský, J; Cabal, J; Kassa, J; Kuca, K | 1 |
| Dohnal, V; Dolezal, M; Jun, D; Kuca, K; Musilek, K | 1 |
| Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K | 1 |
| Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V | 1 |
| Dohnal, V; Dolezal, M; Gunn-Moore, F; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V | 1 |
| Cabal, J; Gunn-Moore, F; Jun, D; Kassa, J; Kuca, K; Musilek, K | 1 |
| Acharya, J; Dubey, DK; Gupta, AK; Raza, SK | 1 |
| Acharya, J; Dubey, DK; Gupta, AK; Mazumder, A | 1 |
| Dohnal, V; Jun, D; Kuca, K; Kucera, J; Musilek, K; Opletalova, V | 1 |
| Jeong, HC; Jung, YS; Kang, NS; Park, NJ; Yum, EK | 1 |
| Acharya, J; Kaushik, MP; Rana, H | 1 |
| Arboléas, M; Baati, R; Gillon, E; Jean, L; Kliachyna, M; Loiodice, M; Mercey, G; Nachon, F; Renard, PY; Renou, J; Verdelet, T | 1 |
| Acharya, J; Karade, HN; Kaushik, MP; Valiveti, AK | 1 |
| Acharya, BN; Acharya, J; Bhalerao, U; Karade, HN; Raviraju, G; Valiveti, AK | 1 |
| Alkema, DPW; de Bruijn, HM; de Koning, MC; Joosen, MJA; Klaassen, SD; Nachon, F; van Grol, M; Wille, T; Worek, F | 1 |
| Andrys, R; Fingler, S; Hofmanova, T; Hrvat, NM; Katalinić, M; Kovarik, Z; Malinak, D; Maraković, N; Musilek, K; Prchal, L; Psotka, M; Svobodova, J; Zandona, A; Zorbaz, T; Žunec, S | 1 |
18 other study(ies) available for obidoxime chloride and pralidoxime chloride
| Article | Year |
|---|---|
Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluation of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimida zolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases.
Topics: Animals; Cattle; Cholinesterase Reactivators; Eels; Humans; Imidazoles; Imines; Kinetics; Mice; Organophosphorus Compounds; Receptors, Cholinergic; Soman; Structure-Activity Relationship | 1989 |
Structure-activity relationships for reactivators of organophosphorus-inhibited acetylcholinesterase: quaternary salts of 2-[(hydroxyimino)methyl]imidazole.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Eels; Hydroxylamines; Imidazoles; Mathematics; Organophosphorus Compounds; Soman; Structure-Activity Relationship | 1984 |
Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase.
Topics: Cholinesterase Inhibitors; Enzyme Reactivators; Kinetics; Organophosphates | 2003 |
Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Hydrocarbons, Brominated; Nitrogen; Oximes; Pyridinium Compounds; Rats | 2006 |
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Cholinesterase Inhibitors; Nitriles; Organophosphates; Paraoxon; Pyridinium Compounds | 2006 |
Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Organophosphates; Oximes; Paraoxon; Pyridinium Compounds | 2007 |
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Organophosphates; Oximes; Paraoxon; Rats; Structure-Activity Relationship | 2007 |
Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).
Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Kinetics; Organophosphates; Oximes; Pyridinium Compounds; Structure-Activity Relationship | 2007 |
Synthesis and evaluation of novel bis-pyridinium oximes as reactivators of DFP-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Isoflurophate; Magnetic Resonance Spectroscopy; Oximes | 2009 |
In-vitro regeneration of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing xylene linker.
Topics: Animals; Cholinesterase Inhibitors; Electrophorus; In Vitro Techniques; Oximes; Pyridinium Compounds; Sarin; Xylenes | 2009 |
Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators; Models, Biological; Molecular Structure; Organophosphates; Paraoxon; Pyridinium Compounds; Rats; Stereoisomerism; Structure-Activity Relationship | 2008 |
Reactivation potency of fluorinated pyridinium oximes for acetylcholinesterases inhibited by paraoxon organophosphorus agent.
Topics: Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Houseflies; Molecular Structure; Organophosphorus Compounds; Oximes; Paraoxon | 2009 |
Synthesis and in vitro evaluation of xylene linked carbamoyl bis-pyridinium monooximes as reactivators of organophosphorus (OP) inhibited electric eel acetylcholinesterase (AChE).
Topics: Animals; Cholinesterase Reactivators; Electrophorus; Magnetic Resonance Spectroscopy; Pyridinium Compounds; Spectrophotometry, Infrared | 2011 |
Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Enzyme Reactivators; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Oximes; Phosphorylation | 2012 |
Synthesis and in vitro evaluation of bis-quaternary 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide derivatives as reactivators against sarin and VX inhibited human acetylcholinesterase (hAChE).
Topics: Acetamides; Acetylcholinesterase; Enzyme Assays; Humans; Kinetics; Organothiophosphorus Compounds; Oximes; Protein Binding; Pyridines; Sarin | 2014 |
Synthesis and in vitro reactivation study of isonicotinamide derivatives of 2-(hydroxyimino)-N-(pyridin-3-yl)acetamide as reactivators of Sarin and VX inhibited human acetylcholinesterase (hAChE).
Topics: Acetamides; Aminopyridines; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocyte Membrane; Humans; Kinetics; Niacinamide; Obidoxime Chloride; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Sarin | 2016 |
Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Imidazoles; Kinetics; Male; Models, Molecular; Molecular Docking Simulation; Nerve Agents; Oximes; Pralidoxime Compounds; Rats, Wistar; Sarin | 2017 |
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Halogens; Mice; Nerve Agents; Organophosphorus Compounds; Oximes; Sarin | 2022 |