o-desmethylindomethacin has been researched along with probenecid in 2 studies
| Studies (o-desmethylindomethacin) | Trials (o-desmethylindomethacin) | Recent Studies (post-2010) (o-desmethylindomethacin) | Studies (probenecid) | Trials (probenecid) | Recent Studies (post-2010) (probenecid) |
|---|---|---|---|---|---|
| 27 | 0 | 4 | 3,664 | 292 | 375 |
| Protein | Taxonomy | o-desmethylindomethacin (IC50) | probenecid (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | 3.02 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 6.85 | |
| Solute carrier family 22 member 8 | Homo sapiens (human) | 6.965 | |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | 6.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van den Biggelaar-Martea, M; van Ewijk-Beneken Kolmer, EW; Verwey-van Wissen, CP; Vree, TB | 1 |
| van den Biggelaar-Martea, M; Verwey-van Wissen, CP; Vree, TB | 1 |
2 other study(ies) available for o-desmethylindomethacin and probenecid
| Article | Year |
|---|---|
Probenecid inhibits the glucuronidation of indomethacin and O-desmethylindomethacin in humans. A pilot experiment.
Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Indomethacin; Kidney; Male; Middle Aged; Pilot Projects; Probenecid | 1994 |
Determination of indomethacin, its metabolites and their glucuronides in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis. Preliminary pharmacokinetics and effect of probenecid.
Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Hydrogen-Ion Concentration; Indoleacetic Acids; Indomethacin; Isomerism; Male; Middle Aged; Pilot Projects; Probenecid | 1993 |