Page last updated: 2024-09-04

o-desmethylindomethacin and naltrexone

o-desmethylindomethacin has been researched along with naltrexone in 2 studies

Compound Research Comparison

Studies
(o-desmethylindomethacin)
Trials
(o-desmethylindomethacin)
Recent Studies (post-2010)
(o-desmethylindomethacin)
Studies
(naltrexone)
Trials
(naltrexone)
Recent Studies (post-2010) (naltrexone)
27048,7451,2282,642

Protein Interaction Comparison

ProteinTaxonomyo-desmethylindomethacin (IC50)naltrexone (IC50)
Cytochrome P450 2D6Homo sapiens (human)1
Delta-type opioid receptorMus musculus (house mouse)0.0051
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0063
Kappa-type opioid receptorMus musculus (house mouse)0.006
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0005
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0005
Mu-type opioid receptorHomo sapiens (human)0.006
Delta-type opioid receptorHomo sapiens (human)0.0319
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.0093
Kappa-type opioid receptorHomo sapiens (human)0.0377
Mu-type opioid receptorMus musculus (house mouse)0.0076
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0004

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gallo, RV; Zhen, S1
Kowalczyk, M; Lapo, I; Massi, M; Panocka, I; Sadowski, B; Swiderski, T1

Other Studies

2 other study(ies) available for o-desmethylindomethacin and naltrexone

ArticleYear
The role of norepinephrine in mediating luteinizing hormone release in response to blockade of kappa-opioid receptors in the medial preoptic area.
    Brain research, 1995, Nov-06, Volume: 698, Issue:1-2

    Topics: Animals; Basal Metabolism; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Female; Indomethacin; Luteinizing Hormone; Naltrexone; Norepinephrine; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Secretory Rate

1995
Antidepressant-type effect of the NK3 tachykinin receptor agonist aminosenktide in mouse lines differing in endogenous opioid system activity.
    Peptides, 2001, Volume: 22, Issue:7

    Topics: Analgesia; Animals; Antidepressive Agents; Behavior, Animal; Cell Line; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Mice; Naltrexone; Narcotics; Peptide Fragments; Receptors, Tachykinin; Substance P; Swimming

2001